locus-tag	class	description
CP983_RS00005	COG2409	Drug exporters of the RND superfamily
CP983_RS00010	COG4585	Histidine kinase
CP983_RS00015	COG2197	response regulator
CP983_RS00060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP983_RS00065	COG3284	Transcriptional regulator
CP983_RS00085	COG0395	ABC-type sugar transport system, permease component
CP983_RS00090	COG3842	ATPase activity
CP983_RS00095	COG3842	ATPase activity
CP983_RS00120	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS00145	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS00160	COG2860	membrane
CP983_RS00320	COG2197	response regulator
CP983_RS00330	COG1132	(ABC) transporter
CP983_RS00335	COG1132	(ABC) transporter
CP983_RS00345	COG0515	serine threonine protein kinase
CP983_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS00360	COG0583	DNA-binding transcription factor activity
CP983_RS00395	COG0604	alcohol dehydrogenase
CP983_RS00405	COG0789	Transcriptional regulator
CP983_RS00410	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS00465	COG2223	nitrite transmembrane transporter activity
CP983_RS00475	COG0019	diaminopimelate decarboxylase activity
CP983_RS00490	COG2188	Transcriptional regulator
CP983_RS00525	COG0477	Major facilitator Superfamily
CP983_RS00535	COG0483	inositol monophosphate 1-phosphatase activity
CP983_RS00540	COG0583	DNA-binding transcription factor activity
CP983_RS00545	COG4221	oxidoreductase activity
CP983_RS00580	COG2409	Drug exporters of the RND superfamily
CP983_RS00590	COG0745	RESPONSE REGULATOR receiver
CP983_RS00595	COG5002	protein histidine kinase activity
CP983_RS00650	COG0702	epimerase
CP983_RS00660	COG1295	ribonuclease BN
CP983_RS00665	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CP983_RS00715	COG2197	response regulator
CP983_RS00715	COG3903	Transcriptional regulator
CP983_RS00760	COG3250	beta-galactosidase activity
CP983_RS00780	COG4191	Histidine kinase
CP983_RS00795	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP983_RS00850	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS00870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP983_RS00880	COG3345	alpha-galactosidase
CP983_RS00905	COG0187	DNA topoisomerase II activity
CP983_RS00910	COG3835	regulator
CP983_RS00930	COG4552	Acetyltransferase involved in intracellular survival and related
CP983_RS00945	COG4977	sequence-specific DNA binding
CP983_RS00955	COG4221	oxidoreductase activity
CP983_RS00965	COG1609	Transcriptional regulator
CP983_RS00980	COG0395	ABC-type sugar transport system, permease component
CP983_RS01010	COG1175	transmembrane transport
CP983_RS01025	COG1063	alcohol dehydrogenase
CP983_RS01035	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS01075	COG2267	carboxylic ester hydrolase activity
CP983_RS01100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP983_RS01105	COG4521	taurine ABC transporter
CP983_RS01115	COG2175	clavaminate synthase activity
CP983_RS01120	COG0028	Belongs to the TPP enzyme family
CP983_RS01140	COG0667	Aldo Keto reductase
CP983_RS01160	COG2130	NADP-dependent
CP983_RS01165	COG1063	alcohol dehydrogenase
CP983_RS01195	COG2080	2 iron, 2 sulfur cluster binding
CP983_RS01195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP983_RS01205	COG1733	regulation of RNA biosynthetic process
CP983_RS01230	COG0659	secondary active sulfate transmembrane transporter activity
CP983_RS01250	COG2824	Alkylphosphonate utilization operon protein PhnA
CP983_RS01275	COG0589	response to stress
CP983_RS01285	COG0574	Belongs to the PEP-utilizing enzyme family
CP983_RS01285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP983_RS01335	COG1140	nitrate reductase beta subunit
CP983_RS01380	COG0475	glutathione-regulated potassium exporter activity
CP983_RS01395	COG2205	protein histidine kinase activity
CP983_RS01400	COG0745	RESPONSE REGULATOR receiver
CP983_RS01415	COG0577	efflux transmembrane transporter activity
CP983_RS01415	COG1136	(ABC) transporter
CP983_RS01420	COG0577	efflux transmembrane transporter activity
CP983_RS01420	COG1136	(ABC) transporter
CP983_RS01425	COG0287	Prephenate dehydrogenase
CP983_RS01450	COG2124	cytochrome p450
CP983_RS01455	COG2124	cytochrome p450
CP983_RS01465	COG0475	glutathione-regulated potassium exporter activity
CP983_RS01475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP983_RS01495	COG1132	(ABC) transporter
CP983_RS01510	COG1349	DNA-binding transcription factor activity
CP983_RS01515	COG2223	nitrite transmembrane transporter activity
CP983_RS01555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS01565	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP983_RS01580	COG1136	(ABC) transporter
CP983_RS01580	COG0577	efflux transmembrane transporter activity
CP983_RS01590	COG0596	Alpha beta hydrolase
CP983_RS01625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP983_RS01670	COG3387	PFAM Glycoside hydrolase 15-related
CP983_RS01675	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CP983_RS01680	COG3265	gluconokinase activity
CP983_RS01695	COG4221	oxidoreductase activity
CP983_RS01790	COG0590	tRNA wobble adenosine to inosine editing
CP983_RS01795	COG1309	transcriptional regulator
CP983_RS01810	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS01905	COG0129	dihydroxy-acid dehydratase activity
CP983_RS01915	COG1063	alcohol dehydrogenase
CP983_RS01935	COG2172	sigma factor antagonist activity
CP983_RS01940	COG1366	Belongs to the anti-sigma-factor antagonist family
CP983_RS01945	COG1366	Belongs to the anti-sigma-factor antagonist family
CP983_RS01970	COG1191	sigma factor activity
CP983_RS02000	COG2226	methyltransferase
CP983_RS02050	COG1120	ATPase activity
CP983_RS02070	COG2197	response regulator
CP983_RS02075	COG2084	Dehydrogenase
CP983_RS02085	COG0477	Major facilitator Superfamily
CP983_RS02105	COG2124	cytochrome p450
CP983_RS02125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS02145	COG3386	PFAM SMP-30 Gluconolaconase
CP983_RS02150	COG0800	Aldolase
CP983_RS02160	COG4948	Mandelate Racemase Muconate Lactonizing
CP983_RS02165	COG2186	Transcriptional regulator
CP983_RS02180	COG0395	ABC-type sugar transport system, permease component
CP983_RS02185	COG1175	transmembrane transport
CP983_RS02195	COG0667	Aldo Keto reductase
CP983_RS02210	COG3739	integral membrane protein
CP983_RS02240	COG1132	(ABC) transporter
CP983_RS02245	COG1228	amidohydrolase
CP983_RS02305	COG2267	carboxylic ester hydrolase activity
CP983_RS02325	COG0477	Major facilitator Superfamily
CP983_RS02335	COG2208	phosphoserine phosphatase activity
CP983_RS02335	COG2172	sigma factor antagonist activity
CP983_RS02335	COG1366	Belongs to the anti-sigma-factor antagonist family
CP983_RS02350	COG3290	protein histidine kinase activity
CP983_RS02365	COG1595	DNA-templated transcription, initiation
CP983_RS02440	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS02465	COG0702	epimerase
CP983_RS02475	COG0438	transferase activity, transferring glycosyl groups
CP983_RS02485	COG1609	Transcriptional regulator
CP983_RS02490	COG3250	beta-galactosidase activity
CP983_RS02495	COG1132	(ABC) transporter
CP983_RS02500	COG0667	Aldo Keto reductase
CP983_RS02505	COG0673	inositol 2-dehydrogenase activity
CP983_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS02570	COG1072	(Pantothenic acid kinase))
CP983_RS02585	COG0395	ABC-type sugar transport system, permease component
CP983_RS02590	COG1175	transmembrane transport
CP983_RS02600	COG1940	carbohydrate kinase activity
CP983_RS02650	COG0673	inositol 2-dehydrogenase activity
CP983_RS02680	COG1846	Transcriptional regulator
CP983_RS02680	COG1940	carbohydrate kinase activity
CP983_RS02685	COG1175	transmembrane transport
CP983_RS02690	COG0395	ABC-type sugar transport system, permease component
CP983_RS02710	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS02720	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS02735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP983_RS02735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP983_RS02745	COG1937	Protein conserved in bacteria
CP983_RS02755	COG1132	(ABC) transporter
CP983_RS02770	COG4264	IucA IucC family
CP983_RS02780	COG0019	diaminopimelate decarboxylase activity
CP983_RS02805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP983_RS02815	COG3345	alpha-galactosidase
CP983_RS02840	COG0789	Transcriptional regulator
CP983_RS02920	COG0515	serine threonine protein kinase
CP983_RS02945	COG2197	response regulator
CP983_RS02980	COG2274	protein secretion by the type I secretion system
CP983_RS02985	COG3832	glyoxalase III activity
CP983_RS03025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP983_RS03050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP983_RS03065	COG3250	beta-galactosidase activity
CP983_RS03095	COG0667	Aldo Keto reductase
CP983_RS03120	COG2124	cytochrome p450
CP983_RS03145	COG0435	Glutathione S-transferase
CP983_RS03170	COG0531	amino acid
CP983_RS03195	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS03210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP983_RS03220	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP983_RS03225	COG1006	Multisubunit Na H antiporter MnhC subunit
CP983_RS03270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP983_RS03270	COG1796	DNA polymerase
CP983_RS03325	COG2706	6-phosphogluconolactonase activity
CP983_RS03335	COG1309	transcriptional regulator
CP983_RS03345	COG1357	PFAM Pentapeptide repeats (8 copies)
CP983_RS03355	COG1595	DNA-templated transcription, initiation
CP983_RS03370	COG1609	Transcriptional regulator
CP983_RS03395	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP983_RS03400	COG1129	ABC transporter
CP983_RS03410	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS03410	COG3347	Dehydrogenase
CP983_RS03415	COG1070	Carbohydrate kinase
CP983_RS03420	COG0247	lactate metabolic process
CP983_RS03425	COG1139	Iron-sulfur cluster binding protein
CP983_RS03430	COG1556	Lactate utilization protein
CP983_RS03435	COG3250	beta-galactosidase activity
CP983_RS03450	COG0577	efflux transmembrane transporter activity
CP983_RS03450	COG1136	(ABC) transporter
CP983_RS03465	COG0542	response to heat
CP983_RS03480	COG0604	alcohol dehydrogenase
CP983_RS03480	COG3321	synthase
CP983_RS03515	COG1609	Transcriptional regulator
CP983_RS03530	COG1121	(ABC) transporter
CP983_RS03540	COG2135	peptidase activity
CP983_RS03565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP983_RS03605	COG1088	dTDP-glucose 4,6-dehydratase activity
CP983_RS03635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP983_RS03640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP983_RS03645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP983_RS03675	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CP983_RS03680	COG0463	Glycosyl transferase, family 2
CP983_RS03685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP983_RS03705	COG1063	alcohol dehydrogenase
CP983_RS03715	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CP983_RS03740	COG0516	GMP reductase activity
CP983_RS03740	COG0517	IMP dehydrogenase activity
CP983_RS03755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP983_RS03765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP983_RS03765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP983_RS03795	COG3409	Peptidoglycan-binding domain 1 protein
CP983_RS03835	COG0242	peptide deformylase activity
CP983_RS03845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP983_RS03860	COG1609	Transcriptional regulator
CP983_RS03875	COG0583	DNA-binding transcription factor activity
CP983_RS03895	COG2814	Major facilitator Superfamily
CP983_RS03930	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS03960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP983_RS03970	COG3284	Transcriptional regulator
CP983_RS03980	COG3485	protocatechuate 3,4-dioxygenase
CP983_RS03990	COG2353	YceI-like domain
CP983_RS04000	COG2326	polyphosphate kinase activity
CP983_RS04010	COG1846	Transcriptional regulator
CP983_RS04020	COG4948	Mandelate Racemase Muconate Lactonizing
CP983_RS04025	COG2610	gluconate transmembrane transporter activity
CP983_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS04085	COG1252	NADH dehydrogenase
CP983_RS04140	COG2197	response regulator
CP983_RS04150	COG2197	response regulator
CP983_RS04230	COG0604	alcohol dehydrogenase
CP983_RS04230	COG3321	synthase
CP983_RS04235	COG0604	alcohol dehydrogenase
CP983_RS04235	COG3321	synthase
CP983_RS04240	COG3321	synthase
CP983_RS04240	COG0604	alcohol dehydrogenase
CP983_RS04245	COG0604	alcohol dehydrogenase
CP983_RS04245	COG3321	synthase
CP983_RS04295	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP983_RS04320	COG1819	glycosyl
CP983_RS04330	COG1131	(ABC) transporter
CP983_RS04405	COG0604	alcohol dehydrogenase
CP983_RS04405	COG3321	synthase
CP983_RS04410	COG3321	synthase
CP983_RS04410	COG3321	synthase
CP983_RS04410	COG0604	alcohol dehydrogenase
CP983_RS04410	COG0604	alcohol dehydrogenase
CP983_RS04430	COG3321	synthase
CP983_RS04430	COG0604	alcohol dehydrogenase
CP983_RS04435	COG0604	alcohol dehydrogenase
CP983_RS04435	COG3321	synthase
CP983_RS04450	COG1819	glycosyl
CP983_RS04465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP983_RS04475	COG1595	DNA-templated transcription, initiation
CP983_RS04480	COG1764	response to oxidative stress
CP983_RS04490	COG1053	succinate dehydrogenase
CP983_RS04500	COG1595	DNA-templated transcription, initiation
CP983_RS04515	COG0438	transferase activity, transferring glycosyl groups
CP983_RS04520	COG0438	transferase activity, transferring glycosyl groups
CP983_RS04525	COG0300	oxidoreductase activity
CP983_RS04550	COG2268	Band 7 protein
CP983_RS04570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP983_RS04575	COG0121	glutamine amidotransferase
CP983_RS04580	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CP983_RS04585	COG3360	Dodecin
CP983_RS04610	COG1366	Belongs to the anti-sigma-factor antagonist family
CP983_RS04625	COG2226	methyltransferase
CP983_RS04640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP983_RS04655	COG0277	FAD linked oxidase domain protein
CP983_RS04660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS04685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP983_RS04690	COG1053	succinate dehydrogenase
CP983_RS04700	COG0583	DNA-binding transcription factor activity
CP983_RS04705	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS04715	COG0583	DNA-binding transcription factor activity
CP983_RS04760	COG0726	polysaccharide deacetylase
CP983_RS04765	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP983_RS04765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP983_RS04775	COG0596	Alpha beta hydrolase
CP983_RS04805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP983_RS04845	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS04850	COG4948	Mandelate Racemase Muconate Lactonizing
CP983_RS04860	COG1129	ABC transporter
CP983_RS04865	COG1879	ABC-type sugar transport system periplasmic component
CP983_RS04870	COG2186	Transcriptional regulator
CP983_RS04895	COG0395	ABC-type sugar transport system, permease component
CP983_RS04900	COG1175	transmembrane transport
CP983_RS04910	COG1609	Transcriptional regulator
CP983_RS04915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP983_RS04960	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS04980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP983_RS04985	COG0297	glycogen (starch) synthase activity
CP983_RS05005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CP983_RS05010	COG2267	carboxylic ester hydrolase activity
CP983_RS05015	COG0596	Alpha beta hydrolase
CP983_RS05025	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP983_RS05040	COG1132	(ABC) transporter
CP983_RS05055	COG0668	transmembrane transport
CP983_RS05065	COG2838	Isocitrate dehydrogenase
CP983_RS05115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS05120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS05130	COG1126	abc transporter atp-binding protein
CP983_RS05135	COG0765	amino acid transport
CP983_RS05145	COG1846	Transcriptional regulator
CP983_RS05150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP983_RS05155	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS05180	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS05185	COG4689	acetoacetate decarboxylase
CP983_RS05200	COG0174	glutamine synthetase
CP983_RS05225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS05230	COG0431	NADPH-dependent FMN reductase
CP983_RS05240	COG1126	abc transporter atp-binding protein
CP983_RS05245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP983_RS05255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS05260	COG0765	amino acid transport
CP983_RS05280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP983_RS05285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP983_RS05290	COG1414	Transcriptional regulator
CP983_RS05315	COG2814	Major facilitator Superfamily
CP983_RS05330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CP983_RS05335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP983_RS05340	COG2186	Transcriptional regulator
CP983_RS05350	COG1609	Transcriptional regulator
CP983_RS05355	COG0673	inositol 2-dehydrogenase activity
CP983_RS05360	COG0673	inositol 2-dehydrogenase activity
CP983_RS05365	COG1609	Transcriptional regulator
CP983_RS05375	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS05380	COG0673	inositol 2-dehydrogenase activity
CP983_RS05390	COG0673	inositol 2-dehydrogenase activity
CP983_RS05415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS05425	COG3718	enzyme involved in inositol metabolism
CP983_RS05430	COG3962	Belongs to the TPP enzyme family
CP983_RS05440	COG2188	Transcriptional regulator
CP983_RS05455	COG0494	nUDIX hydrolase
CP983_RS05460	COG0537	adenosine 5'-monophosphoramidase activity
CP983_RS05510	COG2267	carboxylic ester hydrolase activity
CP983_RS05535	COG0402	S-adenosylhomocysteine deaminase activity
CP983_RS05540	COG0022	dehydrogenase e1 component
CP983_RS05570	COG2188	Transcriptional regulator
CP983_RS05665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP983_RS05675	COG0438	transferase activity, transferring glycosyl groups
CP983_RS05680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP983_RS05870	COG1660	Displays ATPase and GTPase activities
CP983_RS06135	COG4974	Belongs to the 'phage' integrase family
CP983_RS06145	COG0006	proline dipeptidase activity
CP983_RS06165	COG0174	glutamine synthetase
CP983_RS06180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP983_RS06185	COG3548	integral membrane protein
CP983_RS06190	COG3469	chitinase activity
CP983_RS06210	COG0477	Major facilitator Superfamily
CP983_RS06225	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
CP983_RS06230	COG4948	Mandelate Racemase Muconate Lactonizing
CP983_RS06235	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS06245	COG1454	alcohol dehydrogenase
CP983_RS06275	COG0583	DNA-binding transcription factor activity
CP983_RS06280	COG0156	8-amino-7-oxononanoate synthase activity
CP983_RS06285	COG1063	alcohol dehydrogenase
CP983_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS06300	COG0583	DNA-binding transcription factor activity
CP983_RS06360	COG2755	lipolytic protein G-D-S-L family
CP983_RS06375	COG2365	Tyrosine phosphatase family
CP983_RS06395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP983_RS06400	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP983_RS06415	COG1657	PFAM Prenyltransferase squalene oxidase
CP983_RS06425	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP983_RS06435	COG1562	ergosterol biosynthetic process
CP983_RS06440	COG1134	teichoic acid transport
CP983_RS06485	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP983_RS06500	COG1024	Enoyl-CoA hydratase
CP983_RS06520	COG2183	response to ionizing radiation
CP983_RS06525	COG0488	(ABC) transporter
CP983_RS06535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP983_RS06545	COG2936	dipeptidyl-peptidase activity
CP983_RS06555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS06565	COG1113	amino acid transport
CP983_RS06575	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS06580	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP983_RS06590	COG1129	ABC transporter
CP983_RS06600	COG1414	Transcriptional regulator
CP983_RS06610	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP983_RS06610	COG1024	Enoyl-CoA hydratase
CP983_RS06615	COG0183	Belongs to the thiolase family
CP983_RS06625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP983_RS06635	COG3268	Saccharopine dehydrogenase
CP983_RS06640	COG1515	deoxyribonuclease V activity
CP983_RS06665	COG0488	(ABC) transporter
CP983_RS06670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP983_RS06675	COG1834	amidinotransferase
CP983_RS06765	COG1793	dna ligase
CP983_RS06800	COG3485	protocatechuate 3,4-dioxygenase
CP983_RS06805	COG3485	protocatechuate 3,4-dioxygenase
CP983_RS06810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP983_RS06815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP983_RS06825	COG1672	PFAM Archaeal ATPase
CP983_RS06825	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP983_RS06835	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CP983_RS06860	COG3511	phospholipase C
CP983_RS06865	COG0202	RNA polymerase activity
CP983_RS06895	COG0028	Belongs to the TPP enzyme family
CP983_RS06930	COG1414	Transcriptional regulator
CP983_RS06940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP983_RS06945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP983_RS06960	COG0366	Alpha amylase catalytic
CP983_RS06965	COG0395	ABC-type sugar transport system, permease component
CP983_RS06970	COG1175	transmembrane transport
CP983_RS06990	COG3938	Belongs to the proline racemase family
CP983_RS06995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP983_RS07010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP983_RS07045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP983_RS07065	COG3469	chitinase activity
CP983_RS07080	COG1486	melibiose metabolic process
CP983_RS07090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS07100	COG1175	transmembrane transport
CP983_RS07105	COG0395	ABC-type sugar transport system, permease component
CP983_RS07110	COG3250	beta-galactosidase activity
CP983_RS07115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP983_RS07130	COG3903	Transcriptional regulator
CP983_RS07130	COG3629	intracellular signal transduction
CP983_RS07165	COG4585	Histidine kinase
CP983_RS07170	COG2197	response regulator
CP983_RS07175	COG2409	Drug exporters of the RND superfamily
CP983_RS07195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP983_RS07220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP983_RS07235	COG0166	Belongs to the GPI family
CP983_RS07240	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP983_RS07265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP983_RS07275	COG0477	Major facilitator Superfamily
CP983_RS07290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP983_RS07300	COG0438	transferase activity, transferring glycosyl groups
CP983_RS07315	COG0346	lactoylglutathione lyase activity
CP983_RS07320	COG3467	pyridoxamine 5'-phosphate
CP983_RS07330	COG0477	Major facilitator Superfamily
CP983_RS07360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP983_RS07380	COG0438	transferase activity, transferring glycosyl groups
CP983_RS07405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP983_RS07410	COG0747	negative chemotaxis
CP983_RS07470	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP983_RS07475	COG0714	Associated with various cellular activities
CP983_RS07490	COG2723	6-phospho-beta-galactosidase activity
CP983_RS07495	COG0395	ABC-type sugar transport system, permease component
CP983_RS07500	COG1175	transmembrane transport
CP983_RS07505	COG2182	Extracellular solute-binding protein
CP983_RS07515	COG0574	Belongs to the PEP-utilizing enzyme family
CP983_RS07515	COG3848	Pyruvate phosphate dikinase
CP983_RS07520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP983_RS07545	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS07555	COG0045	succinate-CoA ligase (ADP-forming) activity
CP983_RS07565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP983_RS07575	COG2223	nitrite transmembrane transporter activity
CP983_RS07635	COG0673	inositol 2-dehydrogenase activity
CP983_RS07645	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP983_RS07650	COG1129	ABC transporter
CP983_RS07655	COG1940	carbohydrate kinase activity
CP983_RS07670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP983_RS07680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP983_RS07685	COG3383	formate dehydrogenase (NAD+) activity
CP983_RS07700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP983_RS07735	COG0477	Major facilitator Superfamily
CP983_RS07745	COG3250	beta-galactosidase activity
CP983_RS07780	COG0656	L-ascorbic acid biosynthetic process
CP983_RS07800	COG4106	trans-aconitate 2-methyltransferase activity
CP983_RS07810	COG5297	Belongs to the glycosyl hydrolase family 6
CP983_RS07820	COG5297	Belongs to the glycosyl hydrolase family 6
CP983_RS07820	COG4733	cellulase activity
CP983_RS07830	COG2814	Major facilitator Superfamily
CP983_RS07835	COG1846	Transcriptional regulator
CP983_RS07840	COG3401	FG-GAP repeat protein
CP983_RS07845	COG4106	trans-aconitate 2-methyltransferase activity
CP983_RS07845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP983_RS07850	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP983_RS07880	COG1140	nitrate reductase beta subunit
CP983_RS07895	COG0443	Heat shock 70 kDa protein
CP983_RS07970	COG0028	Belongs to the TPP enzyme family
CP983_RS07995	COG0693	protein deglycase activity
CP983_RS08005	COG0488	(ABC) transporter
CP983_RS08010	COG0406	alpha-ribazole phosphatase activity
CP983_RS08080	COG1793	dna ligase
CP983_RS08080	COG3285	dna ligase
CP983_RS08095	COG4948	Mandelate Racemase Muconate Lactonizing
CP983_RS08130	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP983_RS08135	COG4946	Tricorn protease homolog
CP983_RS08135	COG1506	peptidase
CP983_RS08135	COG0823	Involved in the tonB-independent uptake of proteins
CP983_RS08140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP983_RS08150	COG0310	cobalt ion transport
CP983_RS08155	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CP983_RS08165	COG1122	ATPase activity
CP983_RS08190	COG3250	beta-galactosidase activity
CP983_RS08190	COG5297	Belongs to the glycosyl hydrolase family 6
CP983_RS08195	COG2226	methyltransferase
CP983_RS08200	COG2208	phosphoserine phosphatase activity
CP983_RS08200	COG2172	sigma factor antagonist activity
CP983_RS08200	COG1366	Belongs to the anti-sigma-factor antagonist family
CP983_RS08220	COG0596	Alpha beta hydrolase
CP983_RS08240	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP983_RS08255	COG0604	alcohol dehydrogenase
CP983_RS08260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP983_RS08260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP983_RS08265	COG2301	Belongs to the HpcH HpaI aldolase family
CP983_RS08280	COG0688	phosphatidylethanolamine metabolic process
CP983_RS08290	COG1929	Belongs to the glycerate kinase type-1 family
CP983_RS08305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP983_RS08315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP983_RS08345	COG0640	Transcriptional regulator
CP983_RS08360	COG2267	carboxylic ester hydrolase activity
CP983_RS08365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP983_RS08425	COG2318	DinB family
CP983_RS08480	COG0483	inositol monophosphate 1-phosphatase activity
CP983_RS08505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP983_RS08515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CP983_RS08550	COG2197	response regulator
CP983_RS08555	COG3851	Histidine kinase
CP983_RS08570	COG1953	Uracil, thiamine, allantoin
CP983_RS08580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP983_RS08595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP983_RS08620	COG0542	response to heat
CP983_RS08625	COG0405	Gamma-glutamyltransferase
CP983_RS08635	COG2936	dipeptidyl-peptidase activity
CP983_RS08660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP983_RS08675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP983_RS08685	COG1940	carbohydrate kinase activity
CP983_RS08690	COG2188	Transcriptional regulator
CP983_RS08695	COG0673	inositol 2-dehydrogenase activity
CP983_RS08705	COG2197	response regulator
CP983_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS08745	COG4266	Belongs to the allantoicase family
CP983_RS08750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP983_RS08755	COG1414	Transcriptional regulator
CP983_RS08770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP983_RS08795	COG4264	IucA IucC family
CP983_RS08815	COG0436	Aminotransferase
CP983_RS08825	COG0406	alpha-ribazole phosphatase activity
CP983_RS08840	COG1733	regulation of RNA biosynthetic process
CP983_RS08850	COG0702	epimerase
CP983_RS08870	COG2233	PERMEase
CP983_RS08885	COG2351	hydroxyisourate hydrolase activity
CP983_RS08905	COG0309	Hydrogenase expression formation protein (HypE)
CP983_RS08915	COG0298	carbon dioxide binding
CP983_RS08920	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CP983_RS08925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP983_RS08930	COG0375	protein maturation
CP983_RS08960	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CP983_RS08970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP983_RS08970	COG1024	Enoyl-CoA hydratase
CP983_RS08985	COG3622	Belongs to the hyi family
CP983_RS08990	COG2084	Dehydrogenase
CP983_RS08995	COG0753	catalase activity
CP983_RS09005	COG3960	tartronate-semialdehyde synthase activity
CP983_RS09020	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS09025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP983_RS09030	COG2197	response regulator
CP983_RS09055	COG0598	Magnesium transport protein CorA
CP983_RS09105	COG2197	response regulator
CP983_RS09115	COG0583	DNA-binding transcription factor activity
CP983_RS09140	COG3290	protein histidine kinase activity
CP983_RS09165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP983_RS09170	COG0444	Belongs to the ABC transporter superfamily
CP983_RS09175	COG4172	Belongs to the ABC transporter superfamily
CP983_RS09180	COG3940	Belongs to the glycosyl hydrolase 43 family
CP983_RS09185	COG3940	Belongs to the glycosyl hydrolase 43 family
CP983_RS09195	COG5634	Uncharacterized conserved protein (DUF2278)
CP983_RS09215	COG2252	PERMEase
CP983_RS09220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP983_RS09240	COG3835	regulator
CP983_RS09250	COG1802	Transcriptional regulator
CP983_RS09285	COG1404	Belongs to the peptidase S8 family
CP983_RS09305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP983_RS09315	COG1162	GTPase activity
CP983_RS09335	COG0277	FAD linked oxidase domain protein
CP983_RS09355	COG1175	transmembrane transport
CP983_RS09370	COG1131	(ABC) transporter
CP983_RS09420	COG1136	(ABC) transporter
CP983_RS09420	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP983_RS09425	COG4585	Histidine kinase
CP983_RS09430	COG2197	response regulator
CP983_RS09450	COG0494	nUDIX hydrolase
CP983_RS09470	COG2755	lipolytic protein G-D-S-L family
CP983_RS09490	COG2040	homocysteine
CP983_RS09510	COG3629	intracellular signal transduction
CP983_RS09510	COG3903	Transcriptional regulator
CP983_RS09540	COG4977	sequence-specific DNA binding
CP983_RS09540	COG1917	Cupin 2, conserved barrel domain protein
CP983_RS09555	COG1960	acyl-CoA dehydrogenase activity
CP983_RS09585	COG0175	sulfate reduction
CP983_RS09590	COG0529	Catalyzes the synthesis of activated sulfate
CP983_RS09615	COG1116	anion transmembrane transporter activity
CP983_RS09620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP983_RS09635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP983_RS09670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP983_RS09685	COG1175	transmembrane transport
CP983_RS09695	COG0583	DNA-binding transcription factor activity
CP983_RS09780	COG1280	lysine exporter protein (LysE YggA)
CP983_RS09795	COG0504	CTP synthase activity
CP983_RS09815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CP983_RS09815	COG1116	anion transmembrane transporter activity
CP983_RS09820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP983_RS09830	COG2358	TRAP transporter, solute receptor (TAXI family
CP983_RS09860	COG1404	Belongs to the peptidase S8 family
CP983_RS09945	COG1846	Transcriptional regulator
CP983_RS09945	COG1940	carbohydrate kinase activity
CP983_RS09965	COG2018	Roadblock/LC7 domain
CP983_RS09985	COG1174	glycine betaine transport
CP983_RS10025	COG0745	RESPONSE REGULATOR receiver
CP983_RS10030	COG5002	protein histidine kinase activity
CP983_RS10040	COG5002	protein histidine kinase activity
CP983_RS10045	COG0745	RESPONSE REGULATOR receiver
CP983_RS10050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP983_RS10095	COG4172	Belongs to the ABC transporter superfamily
CP983_RS10100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP983_RS10110	COG0747	negative chemotaxis
CP983_RS10130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP983_RS10150	COG3284	Transcriptional regulator
CP983_RS10155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP983_RS10165	COG1073	alpha beta
CP983_RS10170	COG0596	Alpha beta hydrolase
CP983_RS10185	COG4821	SIS domain
CP983_RS10190	COG1737	Transcriptional regulator
CP983_RS10200	COG1472	Belongs to the glycosyl hydrolase 3 family
CP983_RS10215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP983_RS10220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP983_RS10260	COG0330	HflC and HflK could
CP983_RS10290	COG1121	(ABC) transporter
CP983_RS10300	COG3220	belongs to the UPF0276 family
CP983_RS10320	COG3253	May function as heme-dependent peroxidase
CP983_RS10325	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP983_RS10335	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP983_RS10350	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP983_RS10365	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CP983_RS10370	COG3833	ABC-type maltose transport systems, permease component
CP983_RS10375	COG1175	transmembrane transport
CP983_RS10385	COG3250	beta-galactosidase activity
CP983_RS10390	COG1609	Transcriptional regulator
CP983_RS10395	COG0183	Belongs to the thiolase family
CP983_RS10400	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP983_RS10400	COG1024	Enoyl-CoA hydratase
CP983_RS10435	COG0531	amino acid
CP983_RS10440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP983_RS10445	COG4214	carbohydrate transport
CP983_RS10455	COG4213	ABC transporter substrate-binding protein
CP983_RS10460	COG1940	carbohydrate kinase activity
CP983_RS10465	COG0395	ABC-type sugar transport system, permease component
CP983_RS10470	COG1175	transmembrane transport
CP983_RS10475	COG1653	transport
CP983_RS10485	COG3537	Alpha-1,2-mannosidase
CP983_RS10525	COG2205	protein histidine kinase activity
CP983_RS10530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP983_RS10535	COG0137	argininosuccinate synthase activity
CP983_RS10545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP983_RS10560	COG2340	Cysteine-rich secretory protein family
CP983_RS10565	COG1940	carbohydrate kinase activity
CP983_RS10575	COG2207	Transcriptional regulator
CP983_RS10580	COG2205	protein histidine kinase activity
CP983_RS10585	COG3119	arylsulfatase activity
CP983_RS10585	COG3408	Glycogen debranching enzyme
CP983_RS10620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CP983_RS10635	COG2267	carboxylic ester hydrolase activity
CP983_RS10655	COG1414	Transcriptional regulator
CP983_RS10660	COG3971	2-oxopent-4-enoate hydratase activity
CP983_RS10665	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CP983_RS10670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP983_RS10705	COG0529	Catalyzes the synthesis of activated sulfate
CP983_RS10725	COG1024	Enoyl-CoA hydratase
CP983_RS10735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP983_RS10740	COG2235	arginine
CP983_RS10755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP983_RS10780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP983_RS10785	COG1799	cell septum assembly
CP983_RS10790	COG0243	molybdopterin cofactor binding
CP983_RS10810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP983_RS10820	COG1140	nitrate reductase beta subunit
CP983_RS10870	COG0426	domain, Protein
CP983_RS10870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP983_RS10880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP983_RS10890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS10895	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP983_RS10910	COG4221	oxidoreductase activity
CP983_RS10930	COG3321	synthase
CP983_RS10930	COG0604	alcohol dehydrogenase
CP983_RS10930	COG3321	synthase
CP983_RS10930	COG0604	alcohol dehydrogenase
CP983_RS10945	COG2084	Dehydrogenase
CP983_RS10985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP983_RS11000	COG3903	Transcriptional regulator
CP983_RS11000	COG3629	intracellular signal transduction
CP983_RS11030	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS11040	COG1414	Transcriptional regulator
CP983_RS11045	COG1733	regulation of RNA biosynthetic process
CP983_RS11060	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP983_RS11080	COG0367	asparagine synthase
CP983_RS11105	COG0438	transferase activity, transferring glycosyl groups
CP983_RS11115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP983_RS11130	COG4310	Domain of unknown function (DUF2172)
CP983_RS11140	COG1215	transferase activity, transferring glycosyl groups
CP983_RS11155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP983_RS11165	COG0667	Aldo Keto reductase
CP983_RS11175	COG0656	L-ascorbic acid biosynthetic process
CP983_RS11185	COG1063	alcohol dehydrogenase
CP983_RS11195	COG1595	DNA-templated transcription, initiation
CP983_RS11215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP983_RS11220	COG0531	amino acid
CP983_RS11225	COG0569	domain protein
CP983_RS11265	COG0756	dUTP diphosphatase activity
CP983_RS11290	COG2205	protein histidine kinase activity
CP983_RS11295	COG0745	RESPONSE REGULATOR receiver
CP983_RS11305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP983_RS11335	COG1435	thymidine kinase activity
CP983_RS11360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP983_RS11365	COG1802	Transcriptional regulator
CP983_RS11380	COG0612	Peptidase, M16
CP983_RS11385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP983_RS11390	COG0523	cobalamin synthesis protein
CP983_RS11410	COG3290	protein histidine kinase activity
CP983_RS11415	COG4565	transcriptional regulatory protein
CP983_RS11420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP983_RS11435	COG0187	DNA topoisomerase II activity
CP983_RS11450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP983_RS11455	COG1802	Transcriptional regulator
CP983_RS11495	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP983_RS11520	COG0588	phosphoglycerate mutase activity
CP983_RS11535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP983_RS11540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP983_RS11545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP983_RS11580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP983_RS11590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP983_RS11595	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP983_RS11605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP983_RS11630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP983_RS11640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP983_RS11650	COG3321	synthase
CP983_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS11650	COG0604	alcohol dehydrogenase
CP983_RS11660	COG2358	TRAP transporter, solute receptor (TAXI family
CP983_RS11665	COG2205	protein histidine kinase activity
CP983_RS11670	COG0745	RESPONSE REGULATOR receiver
CP983_RS11675	COG1126	abc transporter atp-binding protein
CP983_RS11680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP983_RS11685	COG0765	amino acid transport
CP983_RS11690	COG0765	amino acid transport
CP983_RS11715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP983_RS11725	COG1396	sequence-specific DNA binding
CP983_RS11735	COG0628	permease
CP983_RS11760	COG1917	Cupin 2, conserved barrel domain protein
CP983_RS11760	COG2207	Transcriptional regulator
CP983_RS11765	COG1201	RNA secondary structure unwinding
CP983_RS11770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP983_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS11785	COG1396	sequence-specific DNA binding
CP983_RS11790	COG1058	Belongs to the CinA family
CP983_RS11790	COG1546	Belongs to the CinA family
CP983_RS11800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP983_RS11810	COG1674	ftsk spoiiie
CP983_RS11820	COG2205	protein histidine kinase activity
CP983_RS11820	COG3437	response regulator, receiver
CP983_RS11820	COG4999	Histidine kinase
CP983_RS11820	COG3850	Histidine kinase
CP983_RS11830	COG2770	Histidine kinase
CP983_RS11830	COG2208	phosphoserine phosphatase activity
CP983_RS11865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP983_RS11870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP983_RS11875	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP983_RS11895	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP983_RS11900	COG0612	Peptidase, M16
CP983_RS11905	COG1185	polyribonucleotide nucleotidyltransferase activity
CP983_RS11910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP983_RS11920	COG1674	ftsk spoiiie
CP983_RS12075	COG1404	Belongs to the peptidase S8 family
CP983_RS12110	COG0455	bacterial-type flagellum organization
CP983_RS12125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP983_RS12130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP983_RS12140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP983_RS12155	COG0779	Required for maturation of 30S ribosomal subunits
CP983_RS12215	COG0442	prolyl-tRNA aminoacylation
CP983_RS12230	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP983_RS12235	COG0750	zinc metalloprotease
CP983_RS12240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP983_RS12285	COG0395	ABC-type sugar transport system, permease component
CP983_RS12290	COG4209	transmembrane transport
CP983_RS12295	COG1653	transport
CP983_RS12310	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS12345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP983_RS12350	COG1177	transmembrane transport
CP983_RS12355	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP983_RS12360	COG3842	ATPase activity
CP983_RS12385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP983_RS12390	COG0584	glycerophosphoryl diester phosphodiesterase
CP983_RS12395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP983_RS12415	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS12425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP983_RS12430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP983_RS12455	COG0513	Belongs to the DEAD box helicase family
CP983_RS12460	COG1278	Cold shock
CP983_RS12470	COG3842	ATPase activity
CP983_RS12475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CP983_RS12485	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP983_RS12495	COG0575	Belongs to the CDS family
CP983_RS12500	COG0233	cytoplasmic translational termination
CP983_RS12505	COG0528	UMP kinase activity
CP983_RS12510	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP983_RS12515	COG0052	Belongs to the universal ribosomal protein uS2 family
CP983_RS12520	COG4942	peptidase
CP983_RS12530	COG1191	sigma factor activity
CP983_RS12545	COG0792	nuclease activity
CP983_RS12565	COG0681	Belongs to the peptidase S26 family
CP983_RS12580	COG0335	large ribosomal subunit rRNA binding
CP983_RS12585	COG0336	Belongs to the RNA methyltransferase TrmD family
CP983_RS12590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP983_RS12595	COG1837	Belongs to the UPF0109 family
CP983_RS12600	COG0228	four-way junction DNA binding
CP983_RS12610	COG0442	prolyl-tRNA aminoacylation
CP983_RS12620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP983_RS12630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP983_RS12665	COG0477	Major facilitator Superfamily
CP983_RS12670	COG1196	nuclear chromosome segregation
CP983_RS12685	COG1254	Belongs to the acylphosphatase family
CP983_RS12690	COG2340	Cysteine-rich secretory protein family
CP983_RS12695	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP983_RS12700	COG1733	regulation of RNA biosynthetic process
CP983_RS12705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP983_RS12710	COG0571	ribonuclease III activity
CP983_RS12715	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP983_RS12730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP983_RS12735	COG0742	ribosomal rna small subunit methyltransferase
CP983_RS12745	COG0326	Molecular chaperone. Has ATPase activity
CP983_RS12755	COG1461	Dihydroxyacetone kinase
CP983_RS12760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP983_RS12765	COG0351	phosphomethylpyrimidine kinase
CP983_RS12785	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP983_RS12790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP983_RS12805	COG0776	regulation of translation
CP983_RS12815	COG0066	3-isopropylmalate dehydratase activity
CP983_RS12820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP983_RS12825	COG1414	Transcriptional regulator
CP983_RS12875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP983_RS12880	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP983_RS12890	COG5002	protein histidine kinase activity
CP983_RS12895	COG2018	Roadblock/LC7 domain
CP983_RS12915	COG2018	Roadblock/LC7 domain
CP983_RS12935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP983_RS12940	COG5492	domain, Protein
CP983_RS12945	COG2353	YceI-like domain
CP983_RS12990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP983_RS13005	COG2957	Belongs to the agmatine deiminase family
CP983_RS13010	COG0804	urea catabolic process
CP983_RS13015	COG0832	Belongs to the urease beta subunit family
CP983_RS13015	COG0831	urea catabolic process
CP983_RS13025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP983_RS13030	COG0473	3-isopropylmalate dehydrogenase activity
CP983_RS13055	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS13060	COG0506	proline dehydrogenase activity
CP983_RS13065	COG3835	regulator
CP983_RS13080	COG0477	Major facilitator Superfamily
CP983_RS13090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP983_RS13095	COG0440	acetolactate synthase activity
CP983_RS13105	COG5001	Diguanylate cyclase
CP983_RS13115	COG0667	Aldo Keto reductase
CP983_RS13120	COG2133	pyrroloquinoline quinone binding
CP983_RS13130	COG2197	response regulator
CP983_RS13145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP983_RS13150	COG2409	Drug exporters of the RND superfamily
CP983_RS13160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP983_RS13165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP983_RS13175	COG0154	amidase activity
CP983_RS13180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP983_RS13205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP983_RS13215	COG4221	oxidoreductase activity
CP983_RS13220	COG1611	Belongs to the LOG family
CP983_RS13240	COG0482	sulfurtransferase activity
CP983_RS13280	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP983_RS13285	COG2860	membrane
CP983_RS13290	COG4608	Belongs to the ABC transporter superfamily
CP983_RS13310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP983_RS13330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP983_RS13335	COG0509	glycine decarboxylation via glycine cleavage system
CP983_RS13340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP983_RS13345	COG1760	l-serine dehydratase
CP983_RS13385	COG1376	ErfK ybiS ycfS ynhG family protein
CP983_RS13390	COG1376	ErfK ybiS ycfS ynhG family protein
CP983_RS13405	COG2197	response regulator
CP983_RS13410	COG4585	Histidine kinase
CP983_RS13420	COG1131	(ABC) transporter
CP983_RS13425	COG1132	(ABC) transporter
CP983_RS13430	COG1132	(ABC) transporter
CP983_RS13435	COG1132	(ABC) transporter
CP983_RS13440	COG1132	(ABC) transporter
CP983_RS13465	COG0058	SHG alpha-glucan phosphorylase activity
CP983_RS13475	COG0366	Alpha amylase catalytic
CP983_RS13490	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP983_RS13510	COG1522	sequence-specific DNA binding
CP983_RS13520	COG0667	Aldo Keto reductase
CP983_RS13525	COG1301	dicarboxylic acid transport
CP983_RS13535	COG3290	protein histidine kinase activity
CP983_RS13540	COG4565	transcriptional regulatory protein
CP983_RS13550	COG1175	transmembrane transport
CP983_RS13555	COG0395	ABC-type sugar transport system, permease component
CP983_RS13560	COG0259	pyridoxamine-phosphate oxidase activity
CP983_RS13570	COG0205	6-phosphofructokinase activity
CP983_RS13575	COG0280	phosphate acetyltransferase
CP983_RS13575	COG0857	belongs to the CobB CobQ family
CP983_RS13580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP983_RS13620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP983_RS13620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP983_RS13635	COG2329	Antibiotic biosynthesis monooxygenase
CP983_RS13640	COG2124	cytochrome p450
CP983_RS13650	COG2159	amidohydrolase
CP983_RS13725	COG3850	Histidine kinase
CP983_RS13725	COG0642	Histidine kinase
CP983_RS13730	COG0745	RESPONSE REGULATOR receiver
CP983_RS13750	COG0183	Belongs to the thiolase family
CP983_RS13755	COG0346	lactoylglutathione lyase activity
CP983_RS13770	COG1131	(ABC) transporter
CP983_RS13805	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP983_RS13820	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP983_RS13850	COG4585	Histidine kinase
CP983_RS13855	COG2197	response regulator
CP983_RS13870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP983_RS13875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP983_RS13880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP983_RS13885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP983_RS13890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP983_RS13895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP983_RS13900	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP983_RS13915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP983_RS13920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP983_RS13925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP983_RS13935	COG2890	protein-(glutamine-N5) methyltransferase activity
CP983_RS13940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP983_RS13945	COG0254	rRNA binding
CP983_RS13965	COG0083	homoserine kinase activity
CP983_RS13970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP983_RS13975	COG0460	homoserine dehydrogenase
CP983_RS13980	COG0019	diaminopimelate decarboxylase activity
CP983_RS13985	COG0018	arginyl-trna synthetase
CP983_RS14030	COG2814	Major facilitator Superfamily
CP983_RS14035	COG3251	PFAM MbtH domain protein
CP983_RS14040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP983_RS14055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP983_RS14055	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CP983_RS14075	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP983_RS14080	COG3285	dna ligase
CP983_RS14080	COG1793	dna ligase
CP983_RS14100	COG2205	protein histidine kinase activity
CP983_RS14115	COG0768	penicillin binding
CP983_RS14155	COG0791	NLP P60 protein
CP983_RS14200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP983_RS14215	COG0745	RESPONSE REGULATOR receiver
CP983_RS14220	COG2205	protein histidine kinase activity
CP983_RS14225	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP983_RS14225	COG0567	Dehydrogenase, E1 component
CP983_RS14265	COG0604	alcohol dehydrogenase
CP983_RS14270	COG0281	malic enzyme
CP983_RS14285	COG1126	abc transporter atp-binding protein
CP983_RS14295	COG1595	DNA-templated transcription, initiation
CP983_RS14300	COG4106	trans-aconitate 2-methyltransferase activity
CP983_RS14390	COG0142	geranyltranstransferase activity
CP983_RS14395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP983_RS14405	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CP983_RS14435	COG1597	lipid kinase activity
CP983_RS14450	COG1309	transcriptional regulator
CP983_RS14455	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS14460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP983_RS14465	COG0363	glucosamine-6-phosphate deaminase activity
CP983_RS14475	COG1476	TRANSCRIPTIONal
CP983_RS14480	COG1472	Belongs to the glycosyl hydrolase 3 family
CP983_RS14485	COG0395	ABC-type sugar transport system, permease component
CP983_RS14490	COG1175	transmembrane transport
CP983_RS14495	COG2182	Extracellular solute-binding protein
CP983_RS14500	COG2188	Transcriptional regulator
CP983_RS14555	COG2124	cytochrome p450
CP983_RS14565	COG0242	peptide deformylase activity
CP983_RS14580	COG2199	diguanylate cyclase activity
CP983_RS14580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP983_RS14585	COG5662	AntiSigma factor
CP983_RS14590	COG1595	DNA-templated transcription, initiation
CP983_RS14600	COG2135	peptidase activity
CP983_RS14625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP983_RS14630	COG1162	GTPase activity
CP983_RS14645	COG0483	inositol monophosphate 1-phosphatase activity
CP983_RS14655	COG0753	catalase activity
CP983_RS14695	COG1615	UPF0182 protein
CP983_RS14705	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP983_RS14755	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP983_RS14795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP983_RS14825	COG0596	Alpha beta hydrolase
CP983_RS14865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP983_RS14915	COG0513	Belongs to the DEAD box helicase family
CP983_RS14920	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CP983_RS14925	COG1432	Conserved Protein
CP983_RS14935	COG2095	MarC family integral membrane protein
CP983_RS14950	COG2814	Major facilitator Superfamily
CP983_RS14960	COG0598	Magnesium transport protein CorA
CP983_RS14995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP983_RS15000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP983_RS15010	COG1595	DNA-templated transcription, initiation
CP983_RS15025	COG1024	Enoyl-CoA hydratase
CP983_RS15030	COG2818	Glycosylase
CP983_RS15040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP983_RS15045	COG1611	Belongs to the LOG family
CP983_RS15050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP983_RS15085	COG2197	response regulator
CP983_RS15090	COG4585	Histidine kinase
CP983_RS15100	COG1131	(ABC) transporter
CP983_RS15115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP983_RS15130	COG4608	Belongs to the ABC transporter superfamily
CP983_RS15140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP983_RS15145	COG0601	transmembrane transport
CP983_RS15155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP983_RS15160	COG0747	negative chemotaxis
CP983_RS15165	COG0601	transmembrane transport
CP983_RS15170	COG0444	Belongs to the ABC transporter superfamily
CP983_RS15175	COG4608	Belongs to the ABC transporter superfamily
CP983_RS15200	COG4608	Belongs to the ABC transporter superfamily
CP983_RS15205	COG0444	Belongs to the ABC transporter superfamily
CP983_RS15210	COG0601	transmembrane transport
CP983_RS15220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP983_RS15225	COG1217	gtp-binding protein TYPA
CP983_RS15245	COG1053	succinate dehydrogenase
CP983_RS15310	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS15315	COG0583	DNA-binding transcription factor activity
CP983_RS15340	COG0012	GTP binding
CP983_RS15355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP983_RS15360	COG1570	exodeoxyribonuclease VII activity
CP983_RS15365	COG1722	exodeoxyribonuclease VII activity
CP983_RS15370	COG0778	Nitroreductase
CP983_RS15395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP983_RS15395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP983_RS15400	COG0114	fumarate hydratase activity
CP983_RS15415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP983_RS15435	COG1136	(ABC) transporter
CP983_RS15465	COG0450	alkyl hydroperoxide reductase
CP983_RS15470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP983_RS15480	COG0741	lytic transglycosylase activity
CP983_RS15485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP983_RS15490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP983_RS15505	COG2318	DinB family
CP983_RS15525	COG2885	chlorophyll binding
CP983_RS15545	COG2197	response regulator
CP983_RS15550	COG3850	Histidine kinase
CP983_RS15580	COG2894	cell division
CP983_RS15650	COG2610	gluconate transmembrane transporter activity
CP983_RS15660	COG1414	Transcriptional regulator
CP983_RS15675	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP983_RS15690	COG0436	Aminotransferase
CP983_RS15725	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP983_RS15735	COG0477	Major facilitator Superfamily
CP983_RS15740	COG1309	transcriptional regulator
CP983_RS15770	COG1331	Highly conserved protein containing a thioredoxin domain
CP983_RS15775	COG2255	four-way junction helicase activity
CP983_RS15785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP983_RS15795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP983_RS15815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP983_RS15820	COG2255	four-way junction helicase activity
CP983_RS15845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP983_RS15890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP983_RS15960	COG4941	Belongs to the sigma-70 factor family
CP983_RS15965	COG3795	YCII-related domain
CP983_RS15970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP983_RS16000	COG1404	Belongs to the peptidase S8 family
CP983_RS16005	COG1136	(ABC) transporter
CP983_RS16035	COG2986	histidine ammonia-lyase
CP983_RS16045	COG1024	Enoyl-CoA hydratase
CP983_RS16055	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP983_RS16065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP983_RS16080	COG0424	maF-like protein
CP983_RS16090	COG4770	biotin carboxylase activity
CP983_RS16125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP983_RS16140	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS16160	COG1595	DNA-templated transcription, initiation
CP983_RS16165	COG0745	RESPONSE REGULATOR receiver
CP983_RS16170	COG2205	protein histidine kinase activity
CP983_RS16195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP983_RS16205	COG0583	DNA-binding transcription factor activity
CP983_RS16210	COG2814	Major facilitator Superfamily
CP983_RS16240	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP983_RS16250	COG3845	ABC transporter
CP983_RS16255	COG1744	ABC transporter substrate-binding protein PnrA-like
CP983_RS16260	COG1744	ABC transporter substrate-binding protein PnrA-like
CP983_RS16265	COG1473	amidohydrolase
CP983_RS16265	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP983_RS16270	COG2226	methyltransferase
CP983_RS16280	COG2089	acid synthase
CP983_RS16295	COG1216	Glycosyl transferase, family 2
CP983_RS16315	COG1216	Glycosyl transferase, family 2
CP983_RS16335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP983_RS16335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP983_RS16405	COG2009	succinate dehydrogenase
CP983_RS16415	COG1053	succinate dehydrogenase
CP983_RS16460	COG1309	transcriptional regulator
CP983_RS16465	COG2409	Drug exporters of the RND superfamily
CP983_RS16470	COG0745	RESPONSE REGULATOR receiver
CP983_RS16475	COG2205	protein histidine kinase activity
CP983_RS16490	COG1408	metallophosphoesterase
CP983_RS16500	COG1686	Belongs to the peptidase S11 family
CP983_RS16505	COG1295	ribonuclease BN
CP983_RS16515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CP983_RS16540	COG0180	Tryptophanyl-tRNA synthetase
CP983_RS16545	COG1595	DNA-templated transcription, initiation
CP983_RS16565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP983_RS16570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP983_RS16580	COG0754	glutathionylspermidine amidase activity
CP983_RS16595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP983_RS16600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP983_RS16605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP983_RS16620	COG4176	ABC-type proline glycine betaine transport system permease component
CP983_RS16625	COG0517	IMP dehydrogenase activity
CP983_RS16625	COG4175	Glycine betaine
CP983_RS16635	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS16640	COG2318	DinB family
CP983_RS16710	COG0039	L-malate dehydrogenase activity
CP983_RS16730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP983_RS16750	COG2815	serine threonine protein kinase
CP983_RS16750	COG0515	serine threonine protein kinase
CP983_RS16760	COG0515	serine threonine protein kinase
CP983_RS16760	COG2815	serine threonine protein kinase
CP983_RS16790	COG0138	bifunctional purine biosynthesis protein purh
CP983_RS16820	COG0045	succinate-CoA ligase (ADP-forming) activity
CP983_RS16835	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP983_RS16840	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CP983_RS16845	COG0714	Associated with various cellular activities
CP983_RS16860	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP983_RS16860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP983_RS16900	COG2197	response regulator
CP983_RS16945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP983_RS16945	COG0519	Catalyzes the synthesis of GMP from XMP
CP983_RS16970	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS16975	COG0515	serine threonine protein kinase
CP983_RS16980	COG0515	serine threonine protein kinase
CP983_RS16985	COG0515	serine threonine protein kinase
CP983_RS16985	COG2815	serine threonine protein kinase
CP983_RS16990	COG0515	serine threonine protein kinase
CP983_RS16995	COG2815	serine threonine protein kinase
CP983_RS16995	COG0515	serine threonine protein kinase
CP983_RS17000	COG0515	serine threonine protein kinase
CP983_RS17000	COG2815	serine threonine protein kinase
CP983_RS17010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP983_RS17020	COG0516	GMP reductase activity
CP983_RS17030	COG1595	DNA-templated transcription, initiation
CP983_RS17045	COG0583	DNA-binding transcription factor activity
CP983_RS17055	COG4221	oxidoreductase activity
CP983_RS17065	COG0459	protein refolding
CP983_RS17070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP983_RS17075	COG0726	polysaccharide deacetylase
CP983_RS17080	COG0726	polysaccharide deacetylase
CP983_RS17090	COG4941	Belongs to the sigma-70 factor family
CP983_RS17100	COG1316	TRANSCRIPTIONal
CP983_RS17105	COG1609	Transcriptional regulator
CP983_RS17120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP983_RS17145	COG0802	atpase or kinase
CP983_RS17155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP983_RS17165	COG0736	holo-[acyl-carrier-protein] synthase activity
CP983_RS17175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP983_RS17185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP983_RS17200	COG1072	(Pantothenic acid kinase))
CP983_RS17210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP983_RS17215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP983_RS17220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP983_RS17255	COG2843	Capsule synthesis protein
CP983_RS17265	COG0101	tRNA pseudouridine synthase activity
CP983_RS17270	COG0203	ribosomal protein L17
CP983_RS17275	COG0202	RNA polymerase activity
CP983_RS17280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP983_RS17285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP983_RS17290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP983_RS17295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP983_RS17305	COG0563	adenylate kinase activity
CP983_RS17310	COG0201	protein transport
CP983_RS17315	COG0200	Binds to the 23S rRNA
CP983_RS17320	COG1841	ribosomal large subunit assembly
CP983_RS17325	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP983_RS17330	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP983_RS17335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP983_RS17340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP983_RS17350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP983_RS17355	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP983_RS17360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP983_RS17365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP983_RS17370	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP983_RS17375	COG0255	Belongs to the universal ribosomal protein uL29 family
CP983_RS17380	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP983_RS17385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP983_RS17390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP983_RS17395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP983_RS17400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP983_RS17405	COG0089	rRNA binding
CP983_RS17410	COG0088	Forms part of the polypeptide exit tunnel
CP983_RS17415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP983_RS17420	COG0051	transcription antitermination factor activity, RNA binding
CP983_RS17435	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CP983_RS17440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CP983_RS17455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP983_RS17460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP983_RS17465	COG0049	tRNA binding
CP983_RS17470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP983_RS17480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP983_RS17485	COG0085	RNA polymerase activity
CP983_RS17495	COG0222	ribosome binding
CP983_RS17500	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CP983_RS17515	COG0081	regulation of translation
CP983_RS17520	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CP983_RS17530	COG0250	Participates in transcription elongation, termination and antitermination
CP983_RS17545	COG0436	Aminotransferase
CP983_RS17550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP983_RS17560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP983_RS17565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP983_RS17575	COG0477	Major facilitator Superfamily
CP983_RS17590	COG2030	dehydratase
CP983_RS17595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP983_RS17630	COG3629	intracellular signal transduction
CP983_RS17630	COG3903	Transcriptional regulator
CP983_RS17635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP983_RS17655	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP983_RS17690	COG1660	Displays ATPase and GTPase activities
CP983_RS17780	COG1666	GTP binding
CP983_RS17785	COG2261	transglycosylase associated protein
CP983_RS17800	COG3304	Inner membrane component domain
CP983_RS17805	COG0501	Belongs to the peptidase M48B family
CP983_RS17810	COG1007	ATP synthesis coupled electron transport
CP983_RS17820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP983_RS17825	COG0713	ATP synthesis coupled electron transport
CP983_RS17830	COG0839	Belongs to the complex I subunit 6 family
CP983_RS17835	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP983_RS17840	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP983_RS17845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP983_RS17850	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP983_RS17855	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP983_RS17865	COG4585	Histidine kinase
CP983_RS17875	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP983_RS17875	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP983_RS17880	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP983_RS17895	COG1733	regulation of RNA biosynthetic process
CP983_RS17900	COG0702	epimerase
CP983_RS17915	COG4935	Belongs to the peptidase S8 family
CP983_RS17915	COG2234	aminopeptidase activity
CP983_RS17930	COG0154	amidase activity
CP983_RS17945	COG1131	(ABC) transporter
CP983_RS17960	COG0142	geranyltranstransferase activity
CP983_RS17970	COG0561	phosphatase activity
CP983_RS17985	COG0514	ATP-dependent DNA helicase (RecQ)
CP983_RS17990	COG1007	ATP synthesis coupled electron transport
CP983_RS18000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP983_RS18005	COG0713	ATP synthesis coupled electron transport
CP983_RS18010	COG0839	Belongs to the complex I subunit 6 family
CP983_RS18015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP983_RS18020	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP983_RS18025	COG1034	ATP synthesis coupled electron transport
CP983_RS18030	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP983_RS18040	COG0649	NAD binding
CP983_RS18045	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP983_RS18050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP983_RS18065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP983_RS18065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CP983_RS18070	COG0242	peptide deformylase activity
CP983_RS18090	COG2226	methyltransferase
CP983_RS18120	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP983_RS18135	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP983_RS18140	COG1278	Cold shock
CP983_RS18165	COG4106	trans-aconitate 2-methyltransferase activity
CP983_RS18175	COG1053	succinate dehydrogenase
CP983_RS18185	COG4213	ABC transporter substrate-binding protein
CP983_RS18200	COG0183	Belongs to the thiolase family
CP983_RS18215	COG1309	transcriptional regulator
CP983_RS18240	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP983_RS18250	COG0163	prenyltransferase activity
CP983_RS18265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP983_RS18300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP983_RS18305	COG1333	cytochrome c biogenesis protein
CP983_RS18310	COG0785	Cytochrome C biogenesis protein
CP983_RS18315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP983_RS18325	COG0406	alpha-ribazole phosphatase activity
CP983_RS18330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP983_RS18355	COG0697	spore germination
CP983_RS18360	COG0583	DNA-binding transcription factor activity
CP983_RS18385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP983_RS18400	COG2175	clavaminate synthase activity
CP983_RS18440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS18450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP983_RS18470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS18485	COG0604	alcohol dehydrogenase
CP983_RS18490	COG1733	regulation of RNA biosynthetic process
CP983_RS18500	COG1742	UPF0060 membrane protein
CP983_RS18520	COG1690	Belongs to the RtcB family
CP983_RS18540	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CP983_RS18545	COG0018	arginyl-trna synthetase
CP983_RS18575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP983_RS18585	COG0113	porphobilinogen synthase activity
CP983_RS18600	COG1648	precorrin-2 dehydrogenase activity
CP983_RS18600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP983_RS18605	COG0181	hydroxymethylbilane synthase activity
CP983_RS18610	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP983_RS18615	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP983_RS18670	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP983_RS18710	COG0180	Tryptophanyl-tRNA synthetase
CP983_RS18715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP983_RS18725	COG1129	ABC transporter
CP983_RS18725	COG0842	Transport permease protein
CP983_RS18740	COG4991	sh3 domain protein
CP983_RS18750	COG0129	dihydroxy-acid dehydratase activity
CP983_RS18760	COG1082	Xylose isomerase domain protein TIM barrel
CP983_RS18765	COG0248	Ppx GppA phosphatase
CP983_RS18785	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP983_RS18800	COG1194	a g-specific adenine glycosylase
CP983_RS18805	COG1595	DNA-templated transcription, initiation
CP983_RS18815	COG0745	RESPONSE REGULATOR receiver
CP983_RS18820	COG2205	protein histidine kinase activity
CP983_RS18835	COG0477	Major facilitator Superfamily
CP983_RS18845	COG0739	heme binding
CP983_RS18895	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP983_RS18915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP983_RS18925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP983_RS18930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP983_RS18940	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CP983_RS18960	COG1660	Displays ATPase and GTPase activities
CP983_RS18965	COG2197	response regulator
CP983_RS18980	COG0649	NAD binding
CP983_RS19020	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP983_RS19035	COG0302	gtp cyclohydrolase
CP983_RS19050	COG0037	tRNA processing
CP983_RS19060	COG2027	D-alanyl-D-alanine carboxypeptidase
CP983_RS19065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP983_RS19075	COG0586	Pfam SNARE associated Golgi protein
CP983_RS19080	COG0393	Putative heavy-metal-binding
CP983_RS19085	COG0789	Transcriptional regulator
CP983_RS19090	COG0076	glutamate decarboxylase activity
CP983_RS19110	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS19140	COG0346	lactoylglutathione lyase activity
CP983_RS19145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP983_RS19155	COG0254	rRNA binding
CP983_RS19160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP983_RS19165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP983_RS19170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP983_RS19195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP983_RS19195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP983_RS19225	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP983_RS19255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP983_RS19260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP983_RS19260	COG1754	DNA topoisomerase type I activity
CP983_RS19285	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CP983_RS19290	COG2172	sigma factor antagonist activity
CP983_RS19295	COG1366	Belongs to the anti-sigma-factor antagonist family
CP983_RS19300	COG1205	dead DEAH box helicase
CP983_RS19300	COG1111	helicase
CP983_RS19365	COG0659	secondary active sulfate transmembrane transporter activity
CP983_RS19370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP983_RS19385	COG2267	carboxylic ester hydrolase activity
CP983_RS19420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP983_RS19445	COG0003	Pfam Anion-transporting ATPase
CP983_RS19460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP983_RS19470	COG1408	metallophosphoesterase
CP983_RS19535	COG1674	ftsk spoiiie
CP983_RS19565	COG2188	Transcriptional regulator
CP983_RS19660	COG1316	TRANSCRIPTIONal
CP983_RS19680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP983_RS19685	COG0477	Major facilitator Superfamily
CP983_RS19690	COG3387	PFAM Glycoside hydrolase 15-related
CP983_RS19730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP983_RS19735	COG1595	DNA-templated transcription, initiation
CP983_RS19740	COG4249	Peptidase C14 caspase catalytic subunit p20
CP983_RS19740	COG2319	Wd-40 repeat
CP983_RS19765	COG0701	Predicted permease
CP983_RS19790	COG1595	DNA-templated transcription, initiation
CP983_RS19820	COG2205	protein histidine kinase activity
CP983_RS19855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP983_RS19860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP983_RS19890	COG0693	protein deglycase activity
CP983_RS19895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP983_RS19950	COG2197	response regulator
CP983_RS19955	COG4585	Histidine kinase
CP983_RS19960	COG1136	(ABC) transporter
CP983_RS19960	COG0577	efflux transmembrane transporter activity
CP983_RS19970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP983_RS19985	COG1131	(ABC) transporter
CP983_RS19990	COG3559	Exporter of polyketide antibiotics
CP983_RS20000	COG2124	cytochrome p450
CP983_RS20010	COG2197	response regulator
CP983_RS20015	COG4585	Histidine kinase
CP983_RS20020	COG2197	response regulator
CP983_RS20025	COG4585	Histidine kinase
CP983_RS20050	COG3844	kynureninase activity
CP983_RS20055	COG3483	tryptophan 2,3-dioxygenase activity
CP983_RS20065	COG0477	Major facilitator Superfamily
CP983_RS20070	COG0191	fructose-bisphosphate aldolase activity
CP983_RS20075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP983_RS20090	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP983_RS20120	COG0542	response to heat
CP983_RS20155	COG4213	ABC transporter substrate-binding protein
CP983_RS20170	COG0789	Transcriptional regulator
CP983_RS20175	COG0484	heat shock protein binding
CP983_RS20180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP983_RS20185	COG0443	Heat shock 70 kDa protein
CP983_RS20190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP983_RS20195	COG2181	nitrate reductase activity
CP983_RS20195	COG0247	lactate metabolic process
CP983_RS20210	COG2814	Major facilitator Superfamily
CP983_RS20225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CP983_RS20330	COG0717	Belongs to the dCTP deaminase family
CP983_RS20380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP983_RS20385	COG0640	Transcriptional regulator
CP983_RS20390	COG2226	methyltransferase
CP983_RS20400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP983_RS20410	COG0515	serine threonine protein kinase
CP983_RS20410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP983_RS20420	COG0640	Transcriptional regulator
CP983_RS20425	COG1473	amidohydrolase
CP983_RS20430	COG0765	amino acid transport
CP983_RS20435	COG1126	abc transporter atp-binding protein
CP983_RS20440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP983_RS20450	COG2205	protein histidine kinase activity
CP983_RS20455	COG0745	RESPONSE REGULATOR receiver
CP983_RS20470	COG1376	ErfK ybiS ycfS ynhG family protein
CP983_RS20525	COG1846	Transcriptional regulator
CP983_RS20535	COG4977	sequence-specific DNA binding
CP983_RS20560	COG0531	amino acid
CP983_RS20565	COG4977	sequence-specific DNA binding
CP983_RS20590	COG0475	glutathione-regulated potassium exporter activity
CP983_RS20605	COG1834	amidinotransferase
CP983_RS20610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP983_RS20615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP983_RS20615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP983_RS20640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP983_RS20685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP983_RS20690	COG2814	Major facilitator Superfamily
CP983_RS20695	COG0248	Ppx GppA phosphatase
CP983_RS20700	COG1335	isochorismatase
CP983_RS20725	COG1764	response to oxidative stress
CP983_RS20730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP983_RS20795	COG0477	Major facilitator Superfamily
CP983_RS20805	COG4585	Histidine kinase
CP983_RS20810	COG2409	Drug exporters of the RND superfamily
CP983_RS20820	COG0714	Associated with various cellular activities
CP983_RS20845	COG3764	Sortase (surface protein transpeptidase)
CP983_RS20895	COG2226	methyltransferase
CP983_RS20895	COG1073	alpha beta
CP983_RS20950	COG0366	Alpha amylase catalytic
CP983_RS20965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP983_RS20985	COG0701	Predicted permease
CP983_RS21000	COG0222	ribosome binding
CP983_RS21040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP983_RS21045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP983_RS21055	COG1289	transmembrane transporter activity
CP983_RS21065	COG0583	DNA-binding transcription factor activity
CP983_RS21080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP983_RS21085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP983_RS21110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP983_RS21125	COG1741	Belongs to the pirin family
CP983_RS21130	COG0477	Major facilitator Superfamily
CP983_RS21150	COG1960	acyl-CoA dehydrogenase activity
CP983_RS21155	COG1362	aminopeptidase activity
CP983_RS21195	COG2226	methyltransferase
CP983_RS21200	COG2814	Major facilitator Superfamily
CP983_RS21215	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP983_RS21220	COG0022	dehydrogenase e1 component
CP983_RS21235	COG0515	serine threonine protein kinase
CP983_RS21240	COG0515	serine threonine protein kinase
CP983_RS21255	COG0604	alcohol dehydrogenase
CP983_RS21255	COG3321	synthase
CP983_RS21255	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS21310	COG1309	transcriptional regulator
CP983_RS21315	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP983_RS21340	COG1960	acyl-CoA dehydrogenase activity
CP983_RS21360	COG1733	regulation of RNA biosynthetic process
CP983_RS21365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CP983_RS21380	COG1716	ATPase activity
CP983_RS21385	COG1716	ATPase activity
CP983_RS21400	COG0768	penicillin binding
CP983_RS21410	COG0515	serine threonine protein kinase
CP983_RS21415	COG3764	Sortase (surface protein transpeptidase)
CP983_RS21420	COG3764	Sortase (surface protein transpeptidase)
CP983_RS21435	COG3764	Sortase (surface protein transpeptidase)
CP983_RS21450	COG0705	Rhomboid family
CP983_RS21475	COG0515	serine threonine protein kinase
CP983_RS21495	COG1116	anion transmembrane transporter activity
CP983_RS21515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP983_RS21520	COG0187	DNA topoisomerase II activity
CP983_RS21525	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP983_RS21530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP983_RS21535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP983_RS21540	COG0592	DNA-directed DNA polymerase activity
CP983_RS21550	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CP983_RS21560	COG0594	ribonuclease P activity
CP983_RS21565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP983_RS21570	COG0706	membrane insertase activity
CP983_RS21580	COG0357	Ribosomal RNA small subunit methyltransferase G
CP983_RS21585	COG1192	Involved in chromosome partitioning
CP983_RS21600	COG3118	belongs to the thioredoxin family
CP983_RS21605	COG0492	ferredoxin-NADP+ reductase activity
CP983_RS21615	COG1595	DNA-templated transcription, initiation
CP983_RS21620	COG2815	serine threonine protein kinase
CP983_RS21620	COG0515	serine threonine protein kinase
CP983_RS21635	COG0617	tRNA 3'-terminal CCA addition
CP983_RS21660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP983_RS21660	COG4499	WXG100 protein secretion system (Wss), protein YukC
CP983_RS21685	COG0360	Binds together with S18 to 16S ribosomal RNA
CP983_RS21690	COG0629	single-stranded DNA binding
CP983_RS21695	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP983_RS21700	COG0359	binds to the 23S rRNA
CP983_RS21710	COG0305	Participates in initiation and elongation during chromosome replication
CP983_RS21730	COG2814	Major facilitator Superfamily
CP983_RS21765	COG0626	cystathionine gamma-synthase activity
CP983_RS21770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP983_RS21775	COG1950	PFAM Membrane protein of
CP983_RS21780	COG0662	Cupin 2, conserved barrel domain protein
CP983_RS21805	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP983_RS21820	COG1609	Transcriptional regulator
CP983_RS21825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP983_RS21835	COG1271	oxidase subunit
CP983_RS21840	COG1294	oxidase, subunit
CP983_RS21845	COG4988	ABC transporter
CP983_RS21855	COG0561	phosphatase activity
CP983_RS21870	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP983_RS21875	COG0789	Transcriptional regulator
CP983_RS21890	COG1131	(ABC) transporter
CP983_RS21920	COG0561	phosphatase activity
CP983_RS21925	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP983_RS21935	COG2837	iron assimilation
CP983_RS21950	COG1999	signal sequence binding
CP983_RS21975	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CP983_RS21980	COG0006	proline dipeptidase activity
CP983_RS22000	COG0653	protein targeting
CP983_RS22020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP983_RS22025	COG2815	serine threonine protein kinase
CP983_RS22025	COG0515	serine threonine protein kinase
CP983_RS22030	COG1278	Cold shock
CP983_RS22070	COG1595	DNA-templated transcription, initiation
CP983_RS22075	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS22080	COG0784	Response regulator, receiver
CP983_RS22120	COG0702	epimerase
CP983_RS22125	COG1733	regulation of RNA biosynthetic process
CP983_RS22130	COG1846	Transcriptional regulator
CP983_RS22145	COG0745	RESPONSE REGULATOR receiver
CP983_RS22150	COG2205	protein histidine kinase activity
CP983_RS22160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP983_RS22165	COG0477	Major facilitator Superfamily
CP983_RS22175	COG3467	pyridoxamine 5'-phosphate
CP983_RS22180	COG2353	YceI-like domain
CP983_RS22205	COG1191	sigma factor activity
CP983_RS22210	COG1191	sigma factor activity
CP983_RS22245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP983_RS22260	COG0433	COG0433 Predicted ATPase
CP983_RS22300	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS22315	COG1653	transport
CP983_RS22325	COG0395	ABC-type sugar transport system, permease component
CP983_RS22330	COG3345	alpha-galactosidase
CP983_RS22375	COG0477	Major facilitator Superfamily
CP983_RS22395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP983_RS22420	COG0151	Belongs to the GarS family
CP983_RS22440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP983_RS22450	COG2197	response regulator
CP983_RS22485	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP983_RS22490	COG0047	phosphoribosylformylglycinamidine synthase activity
CP983_RS22495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP983_RS22525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP983_RS22560	COG1643	Atp-dependent helicase
CP983_RS22620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP983_RS22625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP983_RS22630	COG1846	Transcriptional regulator
CP983_RS22635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP983_RS22635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP983_RS22660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP983_RS22665	COG0579	oxidoreductase
CP983_RS22695	COG1252	NADH dehydrogenase
CP983_RS22770	COG1846	Transcriptional regulator
CP983_RS22785	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS22795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP983_RS22810	COG1196	nuclear chromosome segregation
CP983_RS22810	COG0741	lytic transglycosylase activity
CP983_RS22810	COG0739	heme binding
CP983_RS22815	COG0671	phosphoesterase, PA-phosphatase related
CP983_RS22820	COG0277	FAD linked oxidase domain protein
CP983_RS22830	COG0306	phosphate transporter
CP983_RS22840	COG1937	Protein conserved in bacteria
CP983_RS22855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP983_RS22860	COG0581	inorganic phosphate transmembrane transporter activity
CP983_RS22875	COG0406	alpha-ribazole phosphatase activity
CP983_RS22875	COG0494	nUDIX hydrolase
CP983_RS22885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CP983_RS22905	COG1725	Transcriptional regulator
CP983_RS22910	COG0456	acetyltransferase
CP983_RS22915	COG0737	Belongs to the 5'-nucleotidase family
CP983_RS22925	COG1132	(ABC) transporter
CP983_RS22975	COG0745	RESPONSE REGULATOR receiver
CP983_RS22985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP983_RS22990	COG1609	Transcriptional regulator
CP983_RS22995	COG0745	RESPONSE REGULATOR receiver
CP983_RS23025	COG2897	thiosulfate sulfurtransferase activity
CP983_RS23065	COG3485	protocatechuate 3,4-dioxygenase
CP983_RS23075	COG0354	folic acid binding
CP983_RS23080	COG1490	D-aminoacyl-tRNA deacylase activity
CP983_RS23090	COG4552	Acetyltransferase involved in intracellular survival and related
CP983_RS23100	COG2186	Transcriptional regulator
CP983_RS23110	COG2188	Transcriptional regulator
CP983_RS23130	COG0546	phosphoglycolate phosphatase activity
CP983_RS23150	COG3973	AAA domain
CP983_RS23170	COG1733	regulation of RNA biosynthetic process
CP983_RS23175	COG1090	epimerase
CP983_RS23180	COG2267	carboxylic ester hydrolase activity
CP983_RS23215	COG0438	transferase activity, transferring glycosyl groups
CP983_RS23250	COG0588	phosphoglycerate mutase activity
CP983_RS23275	COG5002	protein histidine kinase activity
CP983_RS23295	COG1329	Transcriptional regulator
CP983_RS23300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP983_RS23305	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP983_RS23310	COG0215	cysteine-tRNA ligase activity
CP983_RS23315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP983_RS23335	COG3842	ATPase activity
CP983_RS23395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP983_RS23400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP983_RS23475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP983_RS23495	COG3300	MHYT domain
CP983_RS23495	COG5001	Diguanylate cyclase
CP983_RS23505	COG1105	Belongs to the carbohydrate kinase PfkB family
CP983_RS23510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP983_RS23540	COG0463	Glycosyl transferase, family 2
CP983_RS23560	COG0459	protein refolding
CP983_RS23585	COG2318	DinB family
CP983_RS23605	COG0667	Aldo Keto reductase
CP983_RS23610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP983_RS23615	COG1737	Transcriptional regulator
CP983_RS23675	COG3973	AAA domain
CP983_RS23685	COG1061	Type III restriction enzyme res subunit
CP983_RS23705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP983_RS23725	COG1278	Cold shock
CP983_RS23730	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP983_RS23735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP983_RS23745	COG2814	Major facilitator Superfamily
CP983_RS23790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP983_RS23800	COG2252	PERMEase
CP983_RS23830	COG0667	Aldo Keto reductase
CP983_RS23875	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CP983_RS23885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP983_RS23890	COG0277	FAD linked oxidase domain protein
CP983_RS23890	COG0247	lactate metabolic process
CP983_RS23900	COG5006	permease, DMT superfamily
CP983_RS23920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP983_RS23935	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS23940	COG1024	Enoyl-CoA hydratase
CP983_RS23950	COG0515	serine threonine protein kinase
CP983_RS23950	COG2815	serine threonine protein kinase
CP983_RS23960	COG0259	pyridoxamine-phosphate oxidase activity
CP983_RS23970	COG0583	DNA-binding transcription factor activity
CP983_RS23990	COG4821	SIS domain
CP983_RS24000	COG0596	Alpha beta hydrolase
CP983_RS24000	COG2945	thiolester hydrolase activity
CP983_RS24070	COG1960	acyl-CoA dehydrogenase activity
CP983_RS24075	COG1960	acyl-CoA dehydrogenase activity
CP983_RS24095	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS24100	COG1960	acyl-CoA dehydrogenase activity
CP983_RS24130	COG1024	Enoyl-CoA hydratase
CP983_RS24140	COG1231	oxidoreductase activity
CP983_RS24145	COG2072	flavoprotein involved in K transport
CP983_RS24150	COG1595	DNA-templated transcription, initiation
CP983_RS24200	COG0259	pyridoxamine-phosphate oxidase activity
CP983_RS24220	COG1960	acyl-CoA dehydrogenase activity
CP983_RS24250	COG1280	lysine exporter protein (LysE YggA)
CP983_RS24255	COG1522	sequence-specific DNA binding
CP983_RS24260	COG1309	transcriptional regulator
CP983_RS24270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP983_RS24270	COG0515	serine threonine protein kinase
CP983_RS24280	COG1024	Enoyl-CoA hydratase
CP983_RS24295	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS24320	COG3629	intracellular signal transduction
CP983_RS24320	COG3903	Transcriptional regulator
CP983_RS24360	COG2267	carboxylic ester hydrolase activity
CP983_RS24385	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP983_RS24445	COG1686	Belongs to the peptidase S11 family
CP983_RS24470	COG0386	Belongs to the glutathione peroxidase family
CP983_RS24485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP983_RS24530	COG2197	response regulator
CP983_RS24540	COG3903	Transcriptional regulator
CP983_RS24540	COG3629	intracellular signal transduction
CP983_RS24545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP983_RS24560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP983_RS24580	COG3251	PFAM MbtH domain protein
CP983_RS24595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP983_RS24600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP983_RS24635	COG2197	response regulator
CP983_RS24730	COG2188	Transcriptional regulator
CP983_RS24775	COG0582	viral genome integration into host DNA
CP983_RS24865	COG3209	COG3209 Rhs family protein
CP983_RS24880	COG1215	transferase activity, transferring glycosyl groups
CP983_RS24890	COG1349	DNA-binding transcription factor activity
CP983_RS24905	COG0305	Participates in initiation and elongation during chromosome replication
CP983_RS25045	COG0582	viral genome integration into host DNA
CP983_RS25080	COG1846	Transcriptional regulator
CP983_RS25085	COG3384	dioxygenase
CP983_RS25090	COG1247	-acetyltransferase
CP983_RS25110	COG0477	Major facilitator Superfamily
CP983_RS25115	COG1349	DNA-binding transcription factor activity
CP983_RS25125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP983_RS25125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP983_RS25125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP983_RS25145	COG3191	aminopeptidase activity
CP983_RS25160	COG1970	mechanosensitive ion channel activity
CP983_RS25170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP983_RS25180	COG0477	Major facilitator Superfamily
CP983_RS25200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP983_RS25205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP983_RS25215	COG0315	cyclic pyranopterin monophosphate synthase activity
CP983_RS25220	COG0315	cyclic pyranopterin monophosphate synthase activity
CP983_RS25220	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP983_RS25225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP983_RS25245	COG0454	-acetyltransferase
CP983_RS25250	COG0708	Exodeoxyribonuclease III
CP983_RS25260	COG2072	flavoprotein involved in K transport
CP983_RS25265	COG2267	carboxylic ester hydrolase activity
CP983_RS25270	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS25280	COG0793	Belongs to the peptidase S41A family
CP983_RS25280	COG4946	Tricorn protease homolog
CP983_RS25290	COG2409	Drug exporters of the RND superfamily
CP983_RS25295	COG0442	prolyl-tRNA aminoacylation
CP983_RS25320	COG2226	methyltransferase
CP983_RS25320	COG1073	alpha beta
CP983_RS25335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP983_RS25340	COG1764	response to oxidative stress
CP983_RS25345	COG1846	Transcriptional regulator
CP983_RS25350	COG1122	ATPase activity
CP983_RS25360	COG0310	cobalt ion transport
CP983_RS25395	COG0084	hydrolase, TatD family'
CP983_RS25400	COG3584	3D domain protein
CP983_RS25400	COG3583	domain protein
CP983_RS25405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP983_RS25410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP983_RS25420	COG0488	(ABC) transporter
CP983_RS25460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP983_RS25475	COG2197	response regulator
CP983_RS25485	COG4106	trans-aconitate 2-methyltransferase activity
CP983_RS25500	COG1309	transcriptional regulator
CP983_RS25510	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP983_RS25525	COG0193	aminoacyl-tRNA hydrolase activity
CP983_RS25530	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP983_RS25535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP983_RS25540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP983_RS25550	COG4585	Histidine kinase
CP983_RS25580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP983_RS25625	COG0477	Major facilitator Superfamily
CP983_RS25630	COG1136	(ABC) transporter
CP983_RS25635	COG0577	efflux transmembrane transporter activity
CP983_RS25700	COG2124	cytochrome p450
CP983_RS25715	COG0148	phosphopyruvate hydratase activity
CP983_RS25740	COG1252	NADH dehydrogenase
CP983_RS25745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP983_RS25750	COG1136	(ABC) transporter
CP983_RS25750	COG0577	efflux transmembrane transporter activity
CP983_RS25755	COG1136	(ABC) transporter
CP983_RS25795	COG0183	Belongs to the thiolase family
CP983_RS25800	COG2755	lipolytic protein G-D-S-L family
CP983_RS25815	COG4221	oxidoreductase activity
CP983_RS25835	COG1174	glycine betaine transport
CP983_RS25845	COG2986	histidine ammonia-lyase
CP983_RS25885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP983_RS25890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP983_RS25900	COG1228	amidohydrolase
CP983_RS25910	COG1191	sigma factor activity
CP983_RS25915	COG1366	Belongs to the anti-sigma-factor antagonist family
CP983_RS25945	COG3104	oligopeptide transport
CP983_RS25950	COG0745	RESPONSE REGULATOR receiver
CP983_RS25955	COG2205	protein histidine kinase activity
CP983_RS25970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CP983_RS25980	COG1902	pentaerythritol trinitrate reductase activity
CP983_RS25985	COG0789	Transcriptional regulator
CP983_RS26005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP983_RS26020	COG1316	TRANSCRIPTIONal
CP983_RS26030	COG1316	TRANSCRIPTIONal
CP983_RS26035	COG0463	Glycosyl transferase, family 2
CP983_RS26040	COG1316	TRANSCRIPTIONal
CP983_RS26045	COG1316	TRANSCRIPTIONal
CP983_RS26050	COG1316	TRANSCRIPTIONal
CP983_RS26075	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP983_RS26075	COG0778	Nitroreductase
CP983_RS26080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP983_RS26120	COG1620	l-lactate permease
CP983_RS26125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP983_RS26130	COG2835	tetraacyldisaccharide 4'-kinase activity
CP983_RS26140	COG1482	cell wall glycoprotein biosynthetic process
CP983_RS26155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP983_RS26155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP983_RS26155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP983_RS26160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP983_RS26205	COG0714	Associated with various cellular activities
CP983_RS26225	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP983_RS26230	COG0745	RESPONSE REGULATOR receiver
CP983_RS26235	COG5002	protein histidine kinase activity
CP983_RS26240	COG0823	Involved in the tonB-independent uptake of proteins
CP983_RS26255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP983_RS26260	COG2197	response regulator
CP983_RS26265	COG3214	Protein conserved in bacteria
CP983_RS26275	COG0653	protein targeting
CP983_RS26300	COG2902	Dehydrogenase
CP983_RS26305	COG1134	teichoic acid transport
CP983_RS26320	COG2197	response regulator
CP983_RS26335	COG1846	Transcriptional regulator
CP983_RS26340	COG1764	response to oxidative stress
CP983_RS26350	COG1216	Glycosyl transferase, family 2
CP983_RS26355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP983_RS26360	COG0463	Glycosyl transferase, family 2
CP983_RS26360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP983_RS26365	COG0395	ABC-type sugar transport system, permease component
CP983_RS26370	COG1175	transmembrane transport
CP983_RS26385	COG0515	serine threonine protein kinase
CP983_RS26390	COG0515	serine threonine protein kinase
CP983_RS26395	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP983_RS26410	COG2884	Cell division ATP-binding protein ftsE
CP983_RS26420	COG0793	Belongs to the peptidase S41A family
CP983_RS26425	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP983_RS26455	COG2027	D-alanyl-D-alanine carboxypeptidase
CP983_RS26460	COG2124	cytochrome p450
CP983_RS26470	COG0583	DNA-binding transcription factor activity
CP983_RS26495	COG2223	nitrite transmembrane transporter activity
CP983_RS26525	COG3973	AAA domain
CP983_RS26535	COG0776	regulation of translation
CP983_RS26540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP983_RS26545	COG1678	Uncharacterized ACR, COG1678
CP983_RS26560	COG1175	transmembrane transport
CP983_RS26565	COG0395	ABC-type sugar transport system, permease component
CP983_RS26570	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP983_RS26620	COG3654	unkown
CP983_RS26640	COG4948	Mandelate Racemase Muconate Lactonizing
CP983_RS26665	COG1174	glycine betaine transport
CP983_RS26675	COG1174	glycine betaine transport
CP983_RS26685	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP983_RS26700	COG0277	FAD linked oxidase domain protein
CP983_RS26735	COG1335	isochorismatase
CP983_RS26745	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP983_RS26755	COG1113	amino acid transport
CP983_RS26790	COG1234	tRNA 3'-trailer cleavage
CP983_RS26795	COG1263	PTS System
CP983_RS26800	COG1263	PTS System
CP983_RS26805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP983_RS26810	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP983_RS26820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP983_RS26850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP983_RS26865	COG4555	ABC transporter
CP983_RS26880	COG2733	membrane
CP983_RS26925	COG3903	Transcriptional regulator
CP983_RS26925	COG3629	intracellular signal transduction
CP983_RS26940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP983_RS27015	COG3764	Sortase (surface protein transpeptidase)
CP983_RS27035	COG0706	membrane insertase activity
CP983_RS27045	COG4702	Belongs to the UPF0303 family
CP983_RS27050	COG0673	inositol 2-dehydrogenase activity
CP983_RS27055	COG1940	carbohydrate kinase activity
CP983_RS27065	COG2188	Transcriptional regulator
CP983_RS27070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP983_RS27160	COG3397	chitin binding
CP983_RS27170	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS27185	COG1126	abc transporter atp-binding protein
CP983_RS27190	COG0765	amino acid transport
CP983_RS27195	COG0765	amino acid transport
CP983_RS27200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP983_RS27215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP983_RS27230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS27280	COG0406	alpha-ribazole phosphatase activity
CP983_RS27305	COG0745	RESPONSE REGULATOR receiver
CP983_RS27330	COG1175	transmembrane transport
CP983_RS27355	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CP983_RS27360	COG4977	sequence-specific DNA binding
CP983_RS27370	COG0589	response to stress
CP983_RS27380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP983_RS27415	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP983_RS27440	COG1960	acyl-CoA dehydrogenase activity
CP983_RS27455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP983_RS27460	COG1309	transcriptional regulator
CP983_RS27465	COG0586	Pfam SNARE associated Golgi protein
CP983_RS27475	COG1946	Acyl-CoA thioesterase
CP983_RS27480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP983_RS27495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP983_RS27505	COG0028	Belongs to the TPP enzyme family
CP983_RS27515	COG2356	endonuclease I
CP983_RS27520	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP983_RS27555	COG1472	Belongs to the glycosyl hydrolase 3 family
CP983_RS27560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP983_RS27590	COG0456	acetyltransferase
CP983_RS27590	COG1846	Transcriptional regulator
CP983_RS27610	COG0673	inositol 2-dehydrogenase activity
CP983_RS27625	COG1869	D-ribose catabolic process
CP983_RS27630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS27635	COG1879	ABC-type sugar transport system periplasmic component
CP983_RS27640	COG1129	ABC transporter
CP983_RS27665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP983_RS27690	COG2409	Drug exporters of the RND superfamily
CP983_RS27700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP983_RS27710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS27725	COG3962	Belongs to the TPP enzyme family
CP983_RS27745	COG0456	acetyltransferase
CP983_RS27785	COG0438	transferase activity, transferring glycosyl groups
CP983_RS27795	COG0728	peptidoglycan biosynthetic process
CP983_RS27805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP983_RS27810	COG0438	transferase activity, transferring glycosyl groups
CP983_RS27870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP983_RS27905	COG4770	biotin carboxylase activity
CP983_RS27920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP983_RS27975	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP983_RS27980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS28000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP983_RS28020	COG2091	lysine biosynthetic process via aminoadipic acid
CP983_RS28025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP983_RS28045	COG0477	Major facilitator Superfamily
CP983_RS28050	COG0656	L-ascorbic acid biosynthetic process
CP983_RS28055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CP983_RS28105	COG0629	single-stranded DNA binding
CP983_RS28135	COG2346	COG2346, Truncated hemoglobins
CP983_RS28140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP983_RS28185	COG1486	melibiose metabolic process
CP983_RS28190	COG0395	ABC-type sugar transport system, permease component
CP983_RS28195	COG1175	transmembrane transport
CP983_RS28205	COG1940	carbohydrate kinase activity
CP983_RS28215	COG0668	transmembrane transport
CP983_RS28230	COG1136	(ABC) transporter
CP983_RS28260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP983_RS28320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP983_RS28330	COG0584	glycerophosphoryl diester phosphodiesterase
CP983_RS28345	COG3842	ATPase activity
CP983_RS28350	COG1349	DNA-binding transcription factor activity
CP983_RS28360	COG0395	ABC-type sugar transport system, permease component
CP983_RS28365	COG1175	transmembrane transport
CP983_RS28370	COG1653	transport
CP983_RS28375	COG1070	Carbohydrate kinase
CP983_RS28380	COG0588	phosphoglycerate mutase activity
CP983_RS28395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP983_RS28400	COG1113	amino acid transport
CP983_RS28410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS28415	COG1116	anion transmembrane transporter activity
CP983_RS28420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP983_RS28435	COG1268	BioY protein
CP983_RS28445	COG0515	serine threonine protein kinase
CP983_RS28450	COG1113	amino acid transport
CP983_RS28455	COG0698	ribose 5-phosphate isomerase
CP983_RS28465	COG4552	Acetyltransferase involved in intracellular survival and related
CP983_RS28480	COG3594	Acyltransferase
CP983_RS28490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP983_RS28490	COG0515	serine threonine protein kinase
CP983_RS28495	COG0509	glycine decarboxylation via glycine cleavage system
CP983_RS28510	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP983_RS28515	COG0740	serine-type endopeptidase activity
CP983_RS28520	COG0740	serine-type endopeptidase activity
CP983_RS28525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP983_RS28535	COG0525	valine-tRNA ligase activity
CP983_RS28540	COG0285	dihydrofolate synthase activity
CP983_RS28550	COG0105	UTP biosynthetic process
CP983_RS28555	COG1077	Cell shape determining protein MreB Mrl
CP983_RS28575	COG0772	Belongs to the SEDS family
CP983_RS28625	COG0076	glutamate decarboxylase activity
CP983_RS28630	COG1252	NADH dehydrogenase
CP983_RS28635	COG1595	DNA-templated transcription, initiation
CP983_RS28645	COG0477	Major facilitator Superfamily
CP983_RS28665	COG2326	polyphosphate kinase activity
CP983_RS28670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP983_RS28700	COG1530	ribonuclease E activity
CP983_RS28705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP983_RS28710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP983_RS28715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP983_RS28730	COG3540	Alkaline phosphatase
CP983_RS28750	COG1215	transferase activity, transferring glycosyl groups
CP983_RS28760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP983_RS28770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP983_RS28785	COG0501	Belongs to the peptidase M48B family
CP983_RS28790	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP983_RS28800	COG0799	negative regulation of ribosome biogenesis
CP983_RS28805	COG0588	phosphoglycerate mutase activity
CP983_RS28830	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP983_RS28845	COG0495	leucyl-tRNA aminoacylation
CP983_RS28855	COG1307	EDD domain protein, DegV family
CP983_RS28860	COG1596	polysaccharide export
CP983_RS28860	COG1555	photosystem II stabilization
CP983_RS28865	COG1234	tRNA 3'-trailer cleavage
CP983_RS28875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP983_RS28935	COG2353	YceI-like domain
CP983_RS28955	COG0268	Binds directly to 16S ribosomal RNA
CP983_RS28960	COG0481	GTPase activity
CP983_RS29000	COG1420	regulation of RNA biosynthetic process
CP983_RS29005	COG0484	heat shock protein binding
CP983_RS29030	COG0793	Belongs to the peptidase S41A family
CP983_RS29030	COG4946	Tricorn protease homolog
CP983_RS29035	COG0537	adenosine 5'-monophosphoramidase activity
CP983_RS29040	COG1234	tRNA 3'-trailer cleavage
CP983_RS29045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP983_RS29060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP983_RS29065	COG4948	Mandelate Racemase Muconate Lactonizing
CP983_RS29070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS29095	COG2315	Protein conserved in bacteria
CP983_RS29105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP983_RS29115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP983_RS29150	COG2723	6-phospho-beta-galactosidase activity
CP983_RS29170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP983_RS29185	COG2409	Drug exporters of the RND superfamily
CP983_RS29190	COG4585	Histidine kinase
CP983_RS29195	COG2197	response regulator
CP983_RS29205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP983_RS29210	COG4608	Belongs to the ABC transporter superfamily
CP983_RS29215	COG0444	Belongs to the ABC transporter superfamily
CP983_RS29225	COG0747	negative chemotaxis
CP983_RS29230	COG2186	Transcriptional regulator
CP983_RS29240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP983_RS29275	COG0456	acetyltransferase
CP983_RS29335	COG1381	Involved in DNA repair and RecF pathway recombination
CP983_RS29340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP983_RS29355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP983_RS29360	COG1121	(ABC) transporter
CP983_RS29365	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP983_RS29365	COG3443	Belongs to the bacterial solute-binding protein 9 family
CP983_RS29370	COG0423	glycine-tRNA ligase activity
CP983_RS29405	COG0667	Aldo Keto reductase
CP983_RS29415	COG0456	acetyltransferase
CP983_RS29425	COG0477	Major facilitator Superfamily
CP983_RS29455	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CP983_RS29460	COG1846	Transcriptional regulator
CP983_RS29460	COG1940	carbohydrate kinase activity
CP983_RS29465	COG0574	Belongs to the PEP-utilizing enzyme family
CP983_RS29465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP983_RS29495	COG0642	Histidine kinase
CP983_RS29500	COG0745	RESPONSE REGULATOR receiver
CP983_RS29510	COG0659	secondary active sulfate transmembrane transporter activity
CP983_RS29525	COG1309	transcriptional regulator
CP983_RS29535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP983_RS29535	COG2146	nitrite reductase [NAD(P)H] activity
CP983_RS29540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP983_RS29555	COG2197	response regulator
CP983_RS29595	COG0243	molybdopterin cofactor binding
CP983_RS29600	COG2949	membrane
CP983_RS29610	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP983_RS29620	COG0358	DNA primase activity
CP983_RS29625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP983_RS29640	COG1070	Carbohydrate kinase
CP983_RS29665	COG3263	regulation of cellular component size
CP983_RS29675	COG3387	PFAM Glycoside hydrolase 15-related
CP983_RS29690	COG1294	oxidase, subunit
CP983_RS29700	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS29715	COG0589	response to stress
CP983_RS29735	COG3290	protein histidine kinase activity
CP983_RS29740	COG4565	transcriptional regulatory protein
CP983_RS29755	COG1077	Cell shape determining protein MreB Mrl
CP983_RS29760	COG0515	serine threonine protein kinase
CP983_RS29760	COG2815	serine threonine protein kinase
CP983_RS29775	COG0825	malonyl-CoA metabolic process
CP983_RS29775	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CP983_RS29780	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS29790	COG2186	Transcriptional regulator
CP983_RS29820	COG2835	tetraacyldisaccharide 4'-kinase activity
CP983_RS29820	COG1663	tetraacyldisaccharide 4'-kinase activity
CP983_RS29840	COG4981	capsule polysaccharide biosynthetic process
CP983_RS29890	COG1414	Transcriptional regulator
CP983_RS29895	COG3386	PFAM SMP-30 Gluconolaconase
CP983_RS29945	COG0395	ABC-type sugar transport system, permease component
CP983_RS29955	COG0730	response to heat
CP983_RS29985	COG3507	Belongs to the glycosyl hydrolase 43 family
CP983_RS29995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP983_RS30005	COG4214	carbohydrate transport
CP983_RS30045	COG1597	lipid kinase activity
CP983_RS30055	COG2130	NADP-dependent
CP983_RS30060	COG1764	response to oxidative stress
CP983_RS30090	COG0583	DNA-binding transcription factor activity
CP983_RS30100	COG1309	transcriptional regulator
CP983_RS30125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP983_RS30130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP983_RS30135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP983_RS30155	COG2409	Drug exporters of the RND superfamily
CP983_RS30170	COG0789	Transcriptional regulator
CP983_RS30175	COG0667	Aldo Keto reductase
CP983_RS30190	COG1309	transcriptional regulator
CP983_RS30195	COG0477	Major facilitator Superfamily
CP983_RS30210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP983_RS30255	COG1358	cellular component organization or biogenesis
CP983_RS30270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP983_RS30315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP983_RS30395	COG4122	O-methyltransferase activity
CP983_RS30445	COG3033	Beta-eliminating lyase
CP983_RS30465	COG0183	Belongs to the thiolase family
CP983_RS30470	COG2124	cytochrome p450
CP983_RS30485	COG3845	ABC transporter
CP983_RS30500	COG1657	PFAM Prenyltransferase squalene oxidase
CP983_RS30510	COG3629	intracellular signal transduction
CP983_RS30510	COG3903	Transcriptional regulator
CP983_RS30530	COG0641	radical SAM
CP983_RS30550	COG1309	transcriptional regulator
CP983_RS30555	COG0438	transferase activity, transferring glycosyl groups
CP983_RS30590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS30615	COG2247	cell wall binding repeat
CP983_RS30615	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP983_RS30625	COG0477	Major facilitator Superfamily
CP983_RS30645	COG2197	response regulator
CP983_RS30655	COG4585	Histidine kinase
CP983_RS30660	COG2030	dehydratase
CP983_RS30670	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS30680	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP983_RS30695	COG0800	Aldolase
CP983_RS30700	COG3022	response to hydroperoxide
CP983_RS30705	COG0557	exoribonuclease II activity
CP983_RS30770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP983_RS30800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP983_RS30825	COG0745	RESPONSE REGULATOR receiver
CP983_RS30830	COG2072	flavoprotein involved in K transport
CP983_RS30845	COG2259	Doxx family
CP983_RS30855	COG0667	Aldo Keto reductase
CP983_RS30860	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS30865	COG3540	Alkaline phosphatase
CP983_RS30875	COG2814	Major facilitator Superfamily
CP983_RS30880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP983_RS30910	COG0672	)-iron permease
CP983_RS30915	COG2837	iron assimilation
CP983_RS30925	COG1120	ATPase activity
CP983_RS30930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS30935	COG4558	Periplasmic binding protein
CP983_RS31000	COG1994	Peptidase M50
CP983_RS31020	COG2814	Major facilitator Superfamily
CP983_RS31035	COG0477	Major facilitator Superfamily
CP983_RS31040	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP983_RS31080	COG0174	glutamine synthetase
CP983_RS31085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP983_RS31085	COG1017	nitric oxide dioxygenase activity
CP983_RS31095	COG1959	2 iron, 2 sulfur cluster binding
CP983_RS31135	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP983_RS31145	COG1609	Transcriptional regulator
CP983_RS31155	COG1175	transmembrane transport
CP983_RS31160	COG3833	ABC-type maltose transport systems, permease component
CP983_RS31165	COG0366	Alpha amylase catalytic
CP983_RS31235	COG2197	response regulator
CP983_RS31240	COG4585	Histidine kinase
CP983_RS31250	COG0745	RESPONSE REGULATOR receiver
CP983_RS31305	COG0501	Belongs to the peptidase M48B family
CP983_RS31320	COG0174	glutamine synthetase
CP983_RS31340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP983_RS31345	COG0321	lipoyl(octanoyl) transferase activity
CP983_RS31360	COG1090	epimerase
CP983_RS31365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP983_RS31400	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP983_RS31410	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP983_RS31415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP983_RS31420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP983_RS31445	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP983_RS31460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP983_RS31480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP983_RS31505	COG4585	Histidine kinase
CP983_RS31510	COG2197	response regulator
CP983_RS31515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP983_RS31520	COG0515	serine threonine protein kinase
CP983_RS31520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP983_RS31525	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP983_RS31550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS31560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP983_RS31565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP983_RS31575	COG1376	ErfK ybiS ycfS ynhG family protein
CP983_RS31585	COG1845	cytochrome c oxidase, subunit III
CP983_RS31590	COG2010	Cytochrome c
CP983_RS31595	COG0723	plastoquinol--plastocyanin reductase activity
CP983_RS31600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP983_RS31605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP983_RS31610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP983_RS31615	COG1929	Belongs to the glycerate kinase type-1 family
CP983_RS31625	COG0745	RESPONSE REGULATOR receiver
CP983_RS31630	COG2205	protein histidine kinase activity
CP983_RS31700	COG0003	Pfam Anion-transporting ATPase
CP983_RS31710	COG1940	carbohydrate kinase activity
CP983_RS31735	COG4585	Histidine kinase
CP983_RS31745	COG0205	6-phosphofructokinase activity
CP983_RS31750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP983_RS31765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP983_RS31770	COG0243	molybdopterin cofactor binding
CP983_RS31775	COG2193	ferroxidase activity
CP983_RS31780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP983_RS31790	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP983_RS31795	COG0515	serine threonine protein kinase
CP983_RS31795	COG2815	serine threonine protein kinase
CP983_RS31800	COG2022	thiamine diphosphate biosynthetic process
CP983_RS31810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP983_RS31810	COG2022	thiamine diphosphate biosynthetic process
CP983_RS31830	COG0352	thiamine-phosphate diphosphorylase activity
CP983_RS31855	COG1309	transcriptional regulator
CP983_RS31865	COG3842	ATPase activity
CP983_RS31875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP983_RS31895	COG0714	Associated with various cellular activities
CP983_RS31905	COG0275	rRNA processing
CP983_RS31920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP983_RS31930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP983_RS31935	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP983_RS31945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP983_RS31950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP983_RS31955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP983_RS31960	COG1496	oxidoreductase activity
CP983_RS31970	COG1799	cell septum assembly
CP983_RS31980	COG3599	regulation of cell shape
CP983_RS31985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP983_RS32000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP983_RS32060	COG0587	DNA-directed DNA polymerase activity
CP983_RS32065	COG1432	Conserved Protein
CP983_RS32085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP983_RS32105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP983_RS32110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP983_RS32115	COG0131	Imidazoleglycerol-phosphate dehydratase
CP983_RS32120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP983_RS32125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP983_RS32130	COG0251	oxidation-reduction process
CP983_RS32135	COG0107	imidazoleglycerol-phosphate synthase activity
CP983_RS32155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP983_RS32160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP983_RS32180	COG0134	indole-3-glycerol-phosphate synthase activity
CP983_RS32190	COG0133	tryptophan synthase activity
CP983_RS32195	COG0159	tryptophan synthase activity
CP983_RS32205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CP983_RS32215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP983_RS32220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP983_RS32250	COG0070	glutamate synthase
CP983_RS32250	COG0069	glutamate synthase activity
CP983_RS32250	COG0067	glutamate synthase
CP983_RS32270	COG2304	oxidoreductase activity
CP983_RS32275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP983_RS32285	COG1960	acyl-CoA dehydrogenase activity
CP983_RS32290	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS32295	COG1309	transcriptional regulator
CP983_RS32300	COG0183	Belongs to the thiolase family
CP983_RS32320	COG1024	Enoyl-CoA hydratase
CP983_RS32330	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS32340	COG5640	endopeptidase activity
CP983_RS32355	COG1605	Chorismate mutase
CP983_RS32355	COG0287	Prephenate dehydrogenase
CP983_RS32360	COG0745	RESPONSE REGULATOR receiver
CP983_RS32390	COG0737	Belongs to the 5'-nucleotidase family
CP983_RS32420	COG0411	ABC transporter
CP983_RS32445	COG2050	protein possibly involved in aromatic compounds catabolism
CP983_RS32490	COG1643	Atp-dependent helicase
CP983_RS32510	COG0237	dephospho-CoA kinase activity
CP983_RS32545	COG2267	carboxylic ester hydrolase activity
CP983_RS32550	COG1802	Transcriptional regulator
CP983_RS32555	COG1953	Uracil, thiamine, allantoin
CP983_RS32565	COG0456	acetyltransferase
CP983_RS32600	COG0402	S-adenosylhomocysteine deaminase activity
CP983_RS32605	COG2124	cytochrome p450
CP983_RS32650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP983_RS32655	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP983_RS32690	COG0598	Magnesium transport protein CorA
CP983_RS32695	COG2226	methyltransferase
CP983_RS32700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CP983_RS32700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CP983_RS32705	COG2313	pseudouridylate synthase activity
CP983_RS32715	COG1063	alcohol dehydrogenase
CP983_RS32725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP983_RS32730	COG0584	glycerophosphoryl diester phosphodiesterase
CP983_RS32740	COG0556	nucleotide-excision repair
CP983_RS32765	COG0387	Pfam Sodium calcium exchanger
CP983_RS32770	COG0477	Major facilitator Superfamily
CP983_RS32775	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP983_RS32780	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP983_RS32785	COG1126	abc transporter atp-binding protein
CP983_RS32790	COG0765	amino acid transport
CP983_RS32795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP983_RS32810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP983_RS32835	COG0322	excinuclease ABC activity
CP983_RS32840	COG1660	Displays ATPase and GTPase activities
CP983_RS32845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP983_RS32850	COG1481	regulation of sporulation
CP983_RS32860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP983_RS32865	COG0126	phosphoglycerate kinase activity
CP983_RS32870	COG0149	triose-phosphate isomerase activity
CP983_RS32875	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP983_RS32890	COG0166	Belongs to the GPI family
CP983_RS32905	COG1136	(ABC) transporter
CP983_RS32910	COG1695	Transcriptional regulator
CP983_RS32915	COG1653	transport
CP983_RS32920	COG0366	Alpha amylase catalytic
CP983_RS32925	COG1653	transport
CP983_RS32930	COG1175	transmembrane transport
CP983_RS32935	COG0395	ABC-type sugar transport system, permease component
CP983_RS32940	COG0363	glucosamine-6-phosphate deaminase activity
CP983_RS32955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP983_RS32970	COG0109	protoheme IX farnesyltransferase activity
CP983_RS32985	COG1612	heme a metabolic process
CP983_RS32995	COG1131	(ABC) transporter
CP983_RS33000	COG2746	aminoglycoside 3-N-acetyltransferase activity
CP983_RS33015	COG0719	Fe-S assembly protein
CP983_RS33025	COG0396	ATPase activity
CP983_RS33030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP983_RS33035	COG0822	iron-sulfur transferase activity
CP983_RS33040	COG2151	metal-sulfur cluster biosynthetic enzyme
CP983_RS33050	COG0583	DNA-binding transcription factor activity
CP983_RS33070	COG1733	regulation of RNA biosynthetic process
CP983_RS33075	COG2076	Multidrug Resistance protein
CP983_RS33080	COG3226	Transcriptional regulator
CP983_RS33095	COG2171	N-acyltransferase activity
CP983_RS33105	COG1595	DNA-templated transcription, initiation
CP983_RS33115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP983_RS33120	COG0321	lipoyl(octanoyl) transferase activity
CP983_RS33175	COG1802	Transcriptional regulator
CP983_RS33185	COG1609	Transcriptional regulator
CP983_RS33205	COG1063	alcohol dehydrogenase
CP983_RS33230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP983_RS33235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP983_RS33260	COG1802	Transcriptional regulator
CP983_RS33265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP983_RS33275	COG1175	transmembrane transport
CP983_RS33280	COG0395	ABC-type sugar transport system, permease component
CP983_RS33300	COG3507	Belongs to the glycosyl hydrolase 43 family
CP983_RS33315	COG2755	lipolytic protein G-D-S-L family
CP983_RS33325	COG4677	pectinesterase activity
CP983_RS33340	COG5297	Belongs to the glycosyl hydrolase family 6
CP983_RS33350	COG1595	DNA-templated transcription, initiation
CP983_RS33355	COG2252	PERMEase
CP983_RS33360	COG0768	penicillin binding
CP983_RS33365	COG2197	response regulator
CP983_RS33370	COG4585	Histidine kinase
CP983_RS33385	COG1414	Transcriptional regulator
CP983_RS33395	COG2197	response regulator
CP983_RS33400	COG4585	Histidine kinase
CP983_RS33420	COG1917	Cupin 2, conserved barrel domain protein
CP983_RS33420	COG4977	sequence-specific DNA binding
CP983_RS33435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP983_RS33450	COG5285	phytanoyl-CoA dioxygenase
CP983_RS33455	COG1917	Cupin 2, conserved barrel domain protein
CP983_RS33460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP983_RS33465	COG0456	acetyltransferase
CP983_RS33470	COG2318	DinB family
CP983_RS33475	COG1104	cysteine desulfurase activity
CP983_RS33485	COG0765	amino acid transport
CP983_RS33540	COG1797	cobyrinic acid a,c-diamide synthase activity
CP983_RS33560	COG1492	cobalamin metabolic process
CP983_RS33565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CP983_RS33585	COG0235	Class ii aldolase
CP983_RS33605	COG0488	(ABC) transporter
CP983_RS33655	COG3387	PFAM Glycoside hydrolase 15-related
CP983_RS33680	COG1966	Carbon starvation protein
CP983_RS33695	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP983_RS33715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP983_RS33730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP983_RS33735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP983_RS33755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP983_RS33765	COG0312	modulator of DNA gyrase
CP983_RS33770	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS33785	COG2186	Transcriptional regulator
CP983_RS33790	COG2807	transmembrane transport
CP983_RS33805	COG0588	phosphoglycerate mutase activity
CP983_RS33810	COG3830	Belongs to the UPF0237 family
CP983_RS33810	COG0560	Phosphoserine phosphatase
CP983_RS33820	COG1716	ATPase activity
CP983_RS33820	COG1131	(ABC) transporter
CP983_RS33820	COG0842	Transport permease protein
CP983_RS33830	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CP983_RS33835	COG4221	oxidoreductase activity
CP983_RS33845	COG2197	response regulator
CP983_RS33860	COG1119	ATPase activity
CP983_RS33880	COG1881	PFAM PEBP family protein
CP983_RS33890	COG2094	Belongs to the DNA glycosylase MPG family
CP983_RS33925	COG0647	UMP catabolic process
CP983_RS33930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS33935	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS33940	COG1120	ATPase activity
CP983_RS33960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP983_RS33965	COG0497	DNA recombination
CP983_RS33975	COG0438	transferase activity, transferring glycosyl groups
CP983_RS33975	COG0297	glycogen (starch) synthase activity
CP983_RS33990	COG3387	PFAM Glycoside hydrolase 15-related
CP983_RS33995	COG0504	CTP synthase activity
CP983_RS34000	COG0494	nUDIX hydrolase
CP983_RS34010	COG0686	Belongs to the AlaDH PNT family
CP983_RS34025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP983_RS34030	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP983_RS34035	COG1187	pseudouridine synthase activity
CP983_RS34050	COG0477	Major facilitator Superfamily
CP983_RS34055	COG0494	nUDIX hydrolase
CP983_RS34065	COG3541	Predicted nucleotidyltransferase
CP983_RS34090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP983_RS34100	COG1160	GTP binding
CP983_RS34115	COG3583	domain protein
CP983_RS34120	COG3583	domain protein
CP983_RS34130	COG0411	ABC transporter
CP983_RS34170	COG0671	phosphoesterase, PA-phosphatase related
CP983_RS34175	COG0477	Major facilitator Superfamily
CP983_RS34180	COG1960	acyl-CoA dehydrogenase activity
CP983_RS34185	COG1799	cell septum assembly
CP983_RS34200	COG0330	HflC and HflK could
CP983_RS34215	COG0587	DNA-directed DNA polymerase activity
CP983_RS34220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP983_RS34275	COG1725	Transcriptional regulator
CP983_RS34300	COG0726	polysaccharide deacetylase
CP983_RS34300	COG1649	PFAM Uncharacterised BCR, COG1649
CP983_RS34310	COG0463	Glycosyl transferase, family 2
CP983_RS34330	COG2755	lipolytic protein G-D-S-L family
CP983_RS34335	COG0515	serine threonine protein kinase
CP983_RS34335	COG2815	serine threonine protein kinase
CP983_RS34355	COG1595	DNA-templated transcription, initiation
CP983_RS34390	COG2188	Transcriptional regulator
CP983_RS34395	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CP983_RS34405	COG1309	transcriptional regulator
CP983_RS34410	COG0243	molybdopterin cofactor binding
CP983_RS34415	COG2851	Citrate transporter
CP983_RS34465	COG0640	Transcriptional regulator
CP983_RS34475	COG1960	acyl-CoA dehydrogenase activity
CP983_RS34525	COG3876	Protein conserved in bacteria
CP983_RS34535	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS34545	COG1960	acyl-CoA dehydrogenase activity
CP983_RS34570	COG2149	membrane
CP983_RS34575	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP983_RS34610	COG1063	alcohol dehydrogenase
CP983_RS34615	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS34625	COG3265	gluconokinase activity
CP983_RS34630	COG2186	Transcriptional regulator
CP983_RS34640	COG3012	SEC-C Motif Domain Protein
CP983_RS34645	COG0308	aminopeptidase N
CP983_RS34665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP983_RS34695	COG0667	Aldo Keto reductase
CP983_RS34700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS34710	COG0598	Magnesium transport protein CorA
CP983_RS34715	COG0588	phosphoglycerate mutase activity
CP983_RS34730	COG0215	cysteine-tRNA ligase activity
CP983_RS34760	COG2186	Transcriptional regulator
CP983_RS34770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP983_RS34775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP983_RS34780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP983_RS34785	COG1414	Transcriptional regulator
CP983_RS34790	COG0646	methionine synthase
CP983_RS34790	COG1410	methionine synthase
CP983_RS34795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP983_RS34800	COG0747	negative chemotaxis
CP983_RS34805	COG0747	negative chemotaxis
CP983_RS34810	COG2197	response regulator
CP983_RS34820	COG1994	Peptidase M50
CP983_RS34820	COG0517	IMP dehydrogenase activity
CP983_RS34845	COG1222	aaa ATPase
CP983_RS34850	COG4122	O-methyltransferase activity
CP983_RS34865	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP983_RS34870	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP983_RS34875	COG1609	Transcriptional regulator
CP983_RS34885	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP983_RS34920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP983_RS34925	COG0805	protein transport
CP983_RS34935	COG3973	AAA domain
CP983_RS35000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP983_RS35005	COG0517	IMP dehydrogenase activity
CP983_RS35005	COG4175	Glycine betaine
CP983_RS35010	COG4176	ABC-type proline glycine betaine transport system permease component
CP983_RS35035	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP983_RS35040	COG0531	amino acid
CP983_RS35050	COG0174	glutamine synthetase
CP983_RS35055	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS35060	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS35110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP983_RS35115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP983_RS35120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP983_RS35125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP983_RS35130	COG5002	protein histidine kinase activity
CP983_RS35135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP983_RS35140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP983_RS35140	COG0072	phenylalanine-tRNA ligase activity
CP983_RS35170	COG1649	PFAM Uncharacterised BCR, COG1649
CP983_RS35180	COG0697	spore germination
CP983_RS35285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP983_RS35290	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP983_RS35295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP983_RS35300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP983_RS35305	COG1438	arginine binding
CP983_RS35340	COG0165	Argininosuccinate lyase
CP983_RS35355	COG0477	Major facilitator Superfamily
CP983_RS35360	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS35360	COG0204	Acyl-transferase
CP983_RS35365	COG0584	glycerophosphoryl diester phosphodiesterase
CP983_RS35390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP983_RS35395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP983_RS35400	COG2011	ABC-type metal ion transport system permease component
CP983_RS35405	COG1464	Belongs to the NlpA lipoprotein family
CP983_RS35420	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP983_RS35425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP983_RS35425	COG1648	precorrin-2 dehydrogenase activity
CP983_RS35435	COG0494	nUDIX hydrolase
CP983_RS35490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP983_RS35500	COG0456	acetyltransferase
CP983_RS35500	COG0454	-acetyltransferase
CP983_RS35540	COG1175	transmembrane transport
CP983_RS35545	COG0395	ABC-type sugar transport system, permease component
CP983_RS35575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP983_RS35590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP983_RS35595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP983_RS35615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP983_RS35620	COG1560	Kdo2-lipid A biosynthetic process
CP983_RS35625	COG0438	transferase activity, transferring glycosyl groups
CP983_RS35635	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP983_RS35640	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP983_RS35645	COG0217	transcriptional regulatory protein
CP983_RS35650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP983_RS35655	COG0632	four-way junction helicase activity
CP983_RS35660	COG2255	four-way junction helicase activity
CP983_RS35670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP983_RS35675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP983_RS35680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP983_RS35690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP983_RS35695	COG1196	nuclear chromosome segregation
CP983_RS35700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP983_RS35710	COG0124	histidyl-tRNA synthetase
CP983_RS35725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP983_RS35745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP983_RS35750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP983_RS35755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP983_RS35760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP983_RS35770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP983_RS35775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP983_RS35780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP983_RS35790	COG0006	proline dipeptidase activity
CP983_RS35795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP983_RS35800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP983_RS35810	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP983_RS35815	COG0540	Belongs to the ATCase OTCase family
CP983_RS35820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP983_RS35830	COG0505	Belongs to the CarA family
CP983_RS35835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP983_RS35840	COG0167	dihydroorotate dehydrogenase activity
CP983_RS35845	COG0284	orotidine-5'-phosphate decarboxylase activity
CP983_RS35855	COG0194	GDP metabolic process
CP983_RS35860	COG1758	RNA polymerase activity
CP983_RS35870	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP983_RS35885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP983_RS35895	COG2409	Drug exporters of the RND superfamily
CP983_RS35900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP983_RS35905	COG2390	Transcriptional regulator
CP983_RS35920	COG0531	amino acid
CP983_RS35935	COG2188	Transcriptional regulator
CP983_RS35945	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP983_RS35955	COG3842	ATPase activity
CP983_RS35960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP983_RS35975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP983_RS36000	COG2233	PERMEase
CP983_RS36010	COG0738	Major facilitator superfamily
CP983_RS36015	COG1940	carbohydrate kinase activity
CP983_RS36015	COG1846	Transcriptional regulator
CP983_RS36020	COG1090	epimerase
CP983_RS36035	COG3201	nicotinamide mononucleotide transporter
CP983_RS36040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP983_RS36040	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP983_RS36045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP983_RS36050	COG0140	phosphoribosyl-ATP diphosphatase activity
CP983_RS36055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP983_RS36115	COG1960	acyl-CoA dehydrogenase activity
CP983_RS36150	COG1216	Glycosyl transferase, family 2
CP983_RS36165	COG2270	Major facilitator Superfamily
CP983_RS36175	COG2364	Membrane
CP983_RS36180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP983_RS36210	COG0438	transferase activity, transferring glycosyl groups
CP983_RS36215	COG2755	lipolytic protein G-D-S-L family
CP983_RS36220	COG1984	allophanate hydrolase subunit 2
CP983_RS36225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP983_RS36230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP983_RS36235	COG4336	lyase activity
CP983_RS36240	COG2814	Major facilitator Superfamily
CP983_RS36265	COG0531	amino acid
CP983_RS36285	COG2018	Roadblock/LC7 domain
CP983_RS36305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP983_RS36310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP983_RS36320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP983_RS36330	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CP983_RS36345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP983_RS36355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP983_RS36385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP983_RS36435	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP983_RS36435	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP983_RS36455	COG0531	amino acid
CP983_RS36465	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP983_RS36470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP983_RS36475	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP983_RS36510	COG1175	transmembrane transport
CP983_RS36515	COG0395	ABC-type sugar transport system, permease component
CP983_RS36560	COG0384	phenazine biosynthesis protein PhzF
CP983_RS36630	COG0697	spore germination
CP983_RS36675	COG0747	negative chemotaxis
CP983_RS36680	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP983_RS36695	COG2318	DinB family
CP983_RS36715	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP983_RS36745	COG1968	undecaprenyl-diphosphatase activity
CP983_RS36765	COG0183	Belongs to the thiolase family
CP983_RS36800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP983_RS36850	COG0640	Transcriptional regulator
CP983_RS36860	COG1832	CoA-binding protein
CP983_RS36865	COG0215	cysteine-tRNA ligase activity
CP983_RS36875	COG1739	Uncharacterized protein family UPF0029
CP983_RS36880	COG0420	3'-5' exonuclease activity
CP983_RS36885	COG0419	ATPase involved in DNA repair
CP983_RS36900	COG1522	sequence-specific DNA binding
CP983_RS36915	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS36930	COG0626	cystathionine gamma-synthase activity
CP983_RS37000	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CP983_RS37000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP983_RS37010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP983_RS37015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP983_RS37040	COG0475	glutathione-regulated potassium exporter activity
CP983_RS37060	COG1595	DNA-templated transcription, initiation
CP983_RS37065	COG2188	Transcriptional regulator
CP983_RS37070	COG1940	carbohydrate kinase activity
CP983_RS37075	COG2197	response regulator
CP983_RS37080	COG4585	Histidine kinase
CP983_RS37100	COG3663	DNA glycosylase
CP983_RS37105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP983_RS37130	COG0456	acetyltransferase
CP983_RS37140	COG0577	efflux transmembrane transporter activity
CP983_RS37140	COG1136	(ABC) transporter
CP983_RS37145	COG1136	(ABC) transporter
CP983_RS37160	COG2226	methyltransferase
CP983_RS37185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP983_RS37190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP983_RS37195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP983_RS37200	COG0156	8-amino-7-oxononanoate synthase activity
CP983_RS37220	COG0583	DNA-binding transcription factor activity
CP983_RS37225	COG1280	lysine exporter protein (LysE YggA)
CP983_RS37230	COG0791	NLP P60 protein
CP983_RS37240	COG0740	serine-type endopeptidase activity
CP983_RS37255	COG1309	transcriptional regulator
CP983_RS37260	COG0831	urea catabolic process
CP983_RS37265	COG0832	Belongs to the urease beta subunit family
CP983_RS37270	COG0804	urea catabolic process
CP983_RS37280	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP983_RS37285	COG0829	nickel cation binding
CP983_RS37305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP983_RS37310	COG1834	amidinotransferase
CP983_RS37315	COG1522	sequence-specific DNA binding
CP983_RS37320	COG3279	Response regulator of the LytR AlgR family
CP983_RS37330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP983_RS37335	COG3275	phosphorelay sensor kinase activity
CP983_RS37345	COG0515	serine threonine protein kinase
CP983_RS37345	COG2815	serine threonine protein kinase
CP983_RS37360	COG0205	6-phosphofructokinase activity
CP983_RS37365	COG3442	glutamine amidotransferase
CP983_RS37375	COG0242	peptide deformylase activity
CP983_RS37385	COG1960	acyl-CoA dehydrogenase activity
CP983_RS37400	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS37410	COG1793	dna ligase
CP983_RS37415	COG0492	ferredoxin-NADP+ reductase activity
CP983_RS37430	COG1960	acyl-CoA dehydrogenase activity
CP983_RS37435	COG1960	acyl-CoA dehydrogenase activity
CP983_RS37450	COG5434	Belongs to the glycosyl hydrolase 28 family
CP983_RS37450	COG4632	Exopolysaccharide biosynthesis protein
CP983_RS37465	COG2124	cytochrome p450
CP983_RS37475	COG0586	Pfam SNARE associated Golgi protein
CP983_RS37480	COG4214	carbohydrate transport
CP983_RS37490	COG4213	ABC transporter substrate-binding protein
CP983_RS37500	COG4213	ABC transporter substrate-binding protein
CP983_RS37520	COG1082	Xylose isomerase domain protein TIM barrel
CP983_RS37570	COG2815	serine threonine protein kinase
CP983_RS37570	COG0515	serine threonine protein kinase
CP983_RS37590	COG3631	Ketosteroid isomerase-related protein
CP983_RS37595	COG0702	epimerase
CP983_RS37600	COG0488	(ABC) transporter
CP983_RS37605	COG0488	(ABC) transporter
CP983_RS37620	COG0583	DNA-binding transcription factor activity
CP983_RS37625	COG0110	maltose O-acetyltransferase activity
CP983_RS37630	COG4257	antibiotic catabolic process
CP983_RS37650	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS37670	COG1113	amino acid transport
CP983_RS37705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP983_RS37775	COG2018	Roadblock/LC7 domain
CP983_RS37785	COG1946	Acyl-CoA thioesterase
CP983_RS37800	COG0254	rRNA binding
CP983_RS37810	COG1132	(ABC) transporter
CP983_RS37815	COG1132	(ABC) transporter
CP983_RS37830	COG1301	dicarboxylic acid transport
CP983_RS37840	COG1132	(ABC) transporter
CP983_RS37860	COG1116	anion transmembrane transporter activity
CP983_RS37870	COG0432	Pfam Uncharacterised protein family UPF0047
CP983_RS37875	COG1653	transport
CP983_RS37885	COG2197	response regulator
CP983_RS37895	COG0577	efflux transmembrane transporter activity
CP983_RS37895	COG1136	(ABC) transporter
CP983_RS37970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS37975	COG1120	ATPase activity
CP983_RS37985	COG0367	asparagine synthase
CP983_RS38005	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP983_RS38010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS38055	COG1082	Xylose isomerase domain protein TIM barrel
CP983_RS38060	COG0673	inositol 2-dehydrogenase activity
CP983_RS38065	COG2814	Major facilitator Superfamily
CP983_RS38075	COG1609	Transcriptional regulator
CP983_RS38090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP983_RS38120	COG1222	aaa ATPase
CP983_RS38195	COG3396	Phenylacetate-CoA oxygenase
CP983_RS38200	COG3460	Phenylacetate-CoA oxygenase
CP983_RS38205	COG3396	Phenylacetate-CoA oxygenase
CP983_RS38210	COG2151	metal-sulfur cluster biosynthetic enzyme
CP983_RS38215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP983_RS38255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP983_RS38270	COG2706	6-phosphogluconolactonase activity
CP983_RS38285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP983_RS38300	COG1960	acyl-CoA dehydrogenase activity
CP983_RS38325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP983_RS38330	COG1902	pentaerythritol trinitrate reductase activity
CP983_RS38335	COG0640	Transcriptional regulator
CP983_RS38370	COG0546	phosphoglycolate phosphatase activity
CP983_RS38375	COG0671	phosphoesterase, PA-phosphatase related
CP983_RS38415	COG0584	glycerophosphoryl diester phosphodiesterase
CP983_RS38450	COG0204	Acyl-transferase
CP983_RS38475	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP983_RS38490	COG0515	serine threonine protein kinase
CP983_RS38510	COG3345	alpha-galactosidase
CP983_RS38515	COG1090	epimerase
CP983_RS38525	COG1660	Displays ATPase and GTPase activities
CP983_RS38555	COG4585	Histidine kinase
CP983_RS38560	COG2197	response regulator
CP983_RS38620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP983_RS38635	COG2030	dehydratase
CP983_RS38645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP983_RS38650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP983_RS38660	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS38675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP983_RS38675	COG0512	Glutamine amidotransferase of anthranilate synthase
CP983_RS38685	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS38720	COG1228	amidohydrolase
CP983_RS38760	COG3594	Acyltransferase
CP983_RS38785	COG0326	Molecular chaperone. Has ATPase activity
CP983_RS38800	COG0019	diaminopimelate decarboxylase activity
CP983_RS38805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP983_RS38810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP983_RS38830	COG1796	DNA polymerase
CP983_RS38830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP983_RS38840	COG0673	inositol 2-dehydrogenase activity
CP983_RS38855	COG1653	transport
CP983_RS38860	COG1175	transmembrane transport
CP983_RS38865	COG0395	ABC-type sugar transport system, permease component
CP983_RS38885	COG2608	mercury ion transmembrane transporter activity
CP983_RS38900	COG3387	PFAM Glycoside hydrolase 15-related
CP983_RS38905	COG1349	DNA-binding transcription factor activity
CP983_RS38910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP983_RS38920	COG2813	Specifically methylates the guanine in position
CP983_RS38930	COG1940	carbohydrate kinase activity
CP983_RS38940	COG0698	ribose 5-phosphate isomerase
CP983_RS38980	COG1136	(ABC) transporter
CP983_RS38985	COG0577	efflux transmembrane transporter activity
CP983_RS39010	COG1349	DNA-binding transcription factor activity
CP983_RS39045	COG1215	transferase activity, transferring glycosyl groups
CP983_RS39075	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS39115	COG0596	Alpha beta hydrolase
CP983_RS39130	COG1309	transcriptional regulator
CP983_RS39135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP983_RS39140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CP983_RS39165	COG1366	Belongs to the anti-sigma-factor antagonist family
CP983_RS39170	COG0667	Aldo Keto reductase
CP983_RS39205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP983_RS39275	COG1733	regulation of RNA biosynthetic process
CP983_RS39315	COG0402	S-adenosylhomocysteine deaminase activity
CP983_RS39335	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS39405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP983_RS39410	COG0583	DNA-binding transcription factor activity
CP983_RS39415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP983_RS39430	COG1131	(ABC) transporter
CP983_RS39440	COG1595	DNA-templated transcription, initiation
CP983_RS39465	COG1233	COG1233 Phytoene dehydrogenase and related
CP983_RS39510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CP983_RS39520	COG3851	Histidine kinase
CP983_RS39525	COG2197	response regulator
CP983_RS39535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP983_RS39565	COG0346	lactoylglutathione lyase activity
CP983_RS39570	COG0640	Transcriptional regulator
CP983_RS39600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP983_RS39605	COG4638	Rieske (2fe-2S)
CP983_RS39615	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CP983_RS39635	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS39640	COG0517	IMP dehydrogenase activity
CP983_RS39640	COG4175	Glycine betaine
CP983_RS39645	COG4176	ABC-type proline glycine betaine transport system permease component
CP983_RS39660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP983_RS39690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP983_RS39695	COG4638	Rieske (2fe-2S)
CP983_RS39705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP983_RS39710	COG1760	l-serine dehydratase
CP983_RS39715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP983_RS39720	COG0438	transferase activity, transferring glycosyl groups
CP983_RS39750	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS39760	COG4585	Histidine kinase
CP983_RS39765	COG2197	response regulator
CP983_RS39775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP983_RS39785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP983_RS39790	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CP983_RS39800	COG0395	ABC-type sugar transport system, permease component
CP983_RS39805	COG1175	transmembrane transport
CP983_RS39820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP983_RS39840	COG3507	Belongs to the glycosyl hydrolase 43 family
CP983_RS39885	COG2340	Cysteine-rich secretory protein family
CP983_RS39890	COG1012	belongs to the aldehyde dehydrogenase family
CP983_RS39900	COG3842	ATPase activity
CP983_RS39905	COG1177	transmembrane transport
CP983_RS39910	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP983_RS39930	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP983_RS39940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP983_RS39940	COG1042	CoA-binding domain protein
CP983_RS39940	COG0045	succinate-CoA ligase (ADP-forming) activity
CP983_RS39945	COG1960	acyl-CoA dehydrogenase activity
CP983_RS39960	COG1309	transcriptional regulator
CP983_RS39980	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CP983_RS39995	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS40000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS40005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP983_RS40015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CP983_RS40035	COG3291	Pkd domain containing protein
CP983_RS40090	COG1960	acyl-CoA dehydrogenase activity
CP983_RS40100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CP983_RS40120	COG0395	ABC-type sugar transport system, permease component
CP983_RS40125	COG1175	transmembrane transport
CP983_RS40155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP983_RS40160	COG1993	acr, cog1993
CP983_RS40165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP983_RS40170	COG1968	undecaprenyl-diphosphatase activity
CP983_RS40175	COG2186	Transcriptional regulator
CP983_RS40180	COG1113	amino acid transport
CP983_RS40195	COG2066	Belongs to the glutaminase family
CP983_RS40210	COG1686	Belongs to the peptidase S11 family
CP983_RS40215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CP983_RS40230	COG1695	Transcriptional regulator
CP983_RS40235	COG2226	methyltransferase
CP983_RS40245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP983_RS40255	COG3458	cephalosporin-C deacetylase activity
CP983_RS40275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP983_RS40280	COG2890	protein-(glutamine-N5) methyltransferase activity
CP983_RS40290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP983_RS40295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP983_RS40315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP983_RS40320	COG1902	pentaerythritol trinitrate reductase activity
CP983_RS40320	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP983_RS40345	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS40360	COG1461	Dihydroxyacetone kinase
CP983_RS40365	COG2376	Dihydroxyacetone kinase
CP983_RS40395	COG2326	polyphosphate kinase activity
CP983_RS40410	COG1960	acyl-CoA dehydrogenase activity
CP983_RS40420	COG0515	serine threonine protein kinase
CP983_RS40440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP983_RS40445	COG2070	2-Nitropropane dioxygenase
CP983_RS40465	COG2124	cytochrome p450
CP983_RS40475	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS40525	COG1024	Enoyl-CoA hydratase
CP983_RS40645	COG0640	Transcriptional regulator
CP983_RS40665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP983_RS40670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP983_RS40705	COG0702	epimerase
CP983_RS40710	COG1846	Transcriptional regulator
CP983_RS40715	COG2409	Drug exporters of the RND superfamily
CP983_RS40735	COG4941	Belongs to the sigma-70 factor family
CP983_RS40740	COG2188	Transcriptional regulator
CP983_RS40765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP983_RS40775	COG0667	Aldo Keto reductase
CP983_RS40790	COG0346	lactoylglutathione lyase activity
CP983_RS40795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP983_RS40805	COG0583	DNA-binding transcription factor activity
CP983_RS40810	COG0667	Aldo Keto reductase
CP983_RS40830	COG0842	Transport permease protein
CP983_RS40830	COG1131	(ABC) transporter
CP983_RS40830	COG1716	ATPase activity
CP983_RS40860	COG2318	DinB family
CP983_RS40865	COG1396	sequence-specific DNA binding
CP983_RS40870	COG0740	serine-type endopeptidase activity
CP983_RS40875	COG0740	serine-type endopeptidase activity
CP983_RS40880	COG0596	Alpha beta hydrolase
CP983_RS40895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP983_RS40905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP983_RS40925	COG0328	RNA-DNA hybrid ribonuclease activity
CP983_RS40930	COG2304	oxidoreductase activity
CP983_RS40950	COG0667	Aldo Keto reductase
CP983_RS40965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP983_RS40975	COG0515	serine threonine protein kinase
CP983_RS40975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP983_RS41000	COG2340	Cysteine-rich secretory protein family
CP983_RS41010	COG1846	Transcriptional regulator
CP983_RS41010	COG1940	carbohydrate kinase activity
CP983_RS41015	COG3345	alpha-galactosidase
CP983_RS41030	COG1672	PFAM Archaeal ATPase
CP983_RS41030	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP983_RS41060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP983_RS41100	COG5002	protein histidine kinase activity
CP983_RS41170	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP983_RS41175	COG3281	Trehalose synthase
CP983_RS41240	COG0181	hydroxymethylbilane synthase activity
CP983_RS41265	COG2197	response regulator
CP983_RS41280	COG0745	RESPONSE REGULATOR receiver
CP983_RS41305	COG2223	nitrite transmembrane transporter activity
CP983_RS41310	COG2207	Transcriptional regulator
CP983_RS41330	COG0656	L-ascorbic acid biosynthetic process
CP983_RS41335	COG1609	Transcriptional regulator
CP983_RS41340	COG1621	beta-fructofuranosidase activity
CP983_RS41345	COG0395	ABC-type sugar transport system, permease component
CP983_RS41350	COG1175	transmembrane transport
CP983_RS41360	COG1621	beta-fructofuranosidase activity
CP983_RS41370	COG0596	Alpha beta hydrolase
CP983_RS41380	COG3629	intracellular signal transduction
CP983_RS41380	COG3903	Transcriptional regulator
CP983_RS41415	COG0596	Alpha beta hydrolase
CP983_RS41425	COG0583	DNA-binding transcription factor activity
CP983_RS41430	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS41440	COG0009	L-threonylcarbamoyladenylate synthase
CP983_RS41460	COG3845	ABC transporter
CP983_RS41480	COG0318	PFAM AMP-dependent synthetase and ligase
CP983_RS41490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP983_RS41490	COG3320	Male sterility
CP983_RS41505	COG0640	Transcriptional regulator
CP983_RS41535	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP983_RS41545	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP983_RS41550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS41555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP983_RS41560	COG1120	ATPase activity
CP983_RS41570	COG1132	(ABC) transporter
CP983_RS41580	COG1132	(ABC) transporter
CP983_RS41585	COG2382	esterase
CP983_RS41605	COG0277	FAD linked oxidase domain protein
CP983_RS41655	COG0235	Class ii aldolase
CP983_RS41695	COG0725	ABC transporter, periplasmic molybdate-binding protein
CP983_RS41710	COG2080	2 iron, 2 sulfur cluster binding
CP983_RS41710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP983_RS41720	COG3835	regulator
CP983_RS41745	COG2205	protein histidine kinase activity
CP983_RS41750	COG0745	RESPONSE REGULATOR receiver
CP983_RS41755	COG0477	Major facilitator Superfamily
CP983_RS41760	COG0488	(ABC) transporter
CP983_RS41770	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CP983_RS41790	COG0604	alcohol dehydrogenase
CP983_RS41790	COG3321	synthase
CP983_RS41790	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS41825	COG2508	Transcriptional regulator
CP983_RS41835	COG0411	ABC transporter
CP983_RS41855	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CP983_RS41860	COG1309	transcriptional regulator
CP983_RS41865	COG0277	FAD linked oxidase domain protein
CP983_RS41870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CP983_RS41875	COG0628	permease
CP983_RS41880	COG0477	Major facilitator Superfamily
CP983_RS41940	COG0464	growth
CP983_RS41945	COG1404	Belongs to the peptidase S8 family
CP983_RS41950	COG1674	ftsk spoiiie
CP983_RS42015	COG0789	Transcriptional regulator
CP983_RS42025	COG0438	transferase activity, transferring glycosyl groups
CP983_RS42035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP983_RS42040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP983_RS42080	COG0673	inositol 2-dehydrogenase activity
CP983_RS42085	COG1063	alcohol dehydrogenase
CP983_RS42090	COG0395	ABC-type sugar transport system, permease component
CP983_RS42185	COG1175	transmembrane transport
CP983_RS42190	COG0395	ABC-type sugar transport system, permease component
CP983_RS42205	COG3290	protein histidine kinase activity
CP983_RS42245	COG2124	cytochrome p450
CP983_RS42255	COG1960	acyl-CoA dehydrogenase activity
CP983_RS42260	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS42270	COG1024	Enoyl-CoA hydratase
CP983_RS42280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP983_RS42305	COG2205	protein histidine kinase activity
CP983_RS42310	COG0745	RESPONSE REGULATOR receiver
CP983_RS42325	COG1902	pentaerythritol trinitrate reductase activity
CP983_RS42360	COG0783	Belongs to the Dps family
CP983_RS42380	COG0784	Response regulator, receiver
CP983_RS42380	COG2205	protein histidine kinase activity
CP983_RS42380	COG5002	protein histidine kinase activity
CP983_RS42395	COG0395	ABC-type sugar transport system, permease component
CP983_RS42400	COG1175	transmembrane transport
CP983_RS42415	COG2186	Transcriptional regulator
CP983_RS42420	COG1295	ribonuclease BN
CP983_RS42435	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS42450	COG2409	Drug exporters of the RND superfamily
CP983_RS42465	COG2197	response regulator
CP983_RS42470	COG2837	iron assimilation
CP983_RS42475	COG0542	response to heat
CP983_RS42520	COG1609	Transcriptional regulator
CP983_RS42525	COG1879	ABC-type sugar transport system periplasmic component
CP983_RS42530	COG1129	ABC transporter
CP983_RS42535	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP983_RS42540	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP983_RS42550	COG2318	DinB family
CP983_RS42575	COG0477	Major facilitator Superfamily
CP983_RS42605	COG1175	transmembrane transport
CP983_RS42610	COG0395	ABC-type sugar transport system, permease component
CP983_RS42620	COG0657	acetylesterase activity
CP983_RS42660	COG0473	3-isopropylmalate dehydrogenase activity
CP983_RS42670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP983_RS42730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP983_RS42735	COG0583	DNA-binding transcription factor activity
CP983_RS42745	COG2814	Major facilitator Superfamily
CP983_RS42785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP983_RS42785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP983_RS42825	COG2226	methyltransferase
CP983_RS42835	COG0477	Major facilitator Superfamily
CP983_RS42840	COG3250	beta-galactosidase activity
CP983_RS42845	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS42905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP983_RS42950	COG0604	alcohol dehydrogenase
CP983_RS42970	COG1191	sigma factor activity
CP983_RS42980	COG0395	ABC-type sugar transport system, permease component
CP983_RS43000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP983_RS43090	COG0596	Alpha beta hydrolase
CP983_RS43160	COG2329	Antibiotic biosynthesis monooxygenase
CP983_RS43190	COG3119	arylsulfatase activity
CP983_RS43195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP983_RS43210	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS43245	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP983_RS43260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP983_RS43290	COG4585	Histidine kinase
CP983_RS43295	COG2197	response regulator
CP983_RS43300	COG1131	(ABC) transporter
CP983_RS43325	COG0395	ABC-type sugar transport system, permease component
CP983_RS43330	COG1175	transmembrane transport
CP983_RS43335	COG2182	Extracellular solute-binding protein
CP983_RS43340	COG2188	Transcriptional regulator
CP983_RS43355	COG3033	Beta-eliminating lyase
CP983_RS43365	COG2319	Wd-40 repeat
CP983_RS43365	COG4249	Peptidase C14 caspase catalytic subunit p20
CP983_RS43370	COG1404	Belongs to the peptidase S8 family
CP983_RS43375	COG0488	(ABC) transporter
CP983_RS43380	COG0583	DNA-binding transcription factor activity
CP983_RS43385	COG1028	Short-chain dehydrogenase reductase Sdr
CP983_RS43395	COG3655	Transcriptional regulator
CP983_RS43425	COG1864	DNA RNA non-specific endonuclease
CP983_RS43425	COG3591	Belongs to the peptidase S1B family
CP983_RS43435	COG1196	nuclear chromosome segregation
CP983_RS43435	COG0741	lytic transglycosylase activity
CP983_RS43435	COG0739	heme binding
CP983_RS43565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP983_RS43565	COG1017	nitric oxide dioxygenase activity
CP983_RS43575	COG0463	Glycosyl transferase, family 2
CP983_RS43650	COG0640	Transcriptional regulator