locus-tag	class	description
HUT05_RS00050	COG2226	methyltransferase
HUT05_RS00065	COG1063	alcohol dehydrogenase
HUT05_RS00070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS00110	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS00120	COG1703	isobutyryl-CoA mutase activity
HUT05_RS00120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS00120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS00125	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT05_RS00130	COG0022	dehydrogenase e1 component
HUT05_RS00135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUT05_RS00150	COG3321	synthase
HUT05_RS00150	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS00150	COG0604	alcohol dehydrogenase
HUT05_RS00210	COG0464	growth
HUT05_RS00230	COG1674	ftsk spoiiie
HUT05_RS00250	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HUT05_RS00255	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUT05_RS00275	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT05_RS00445	COG4585	Histidine kinase
HUT05_RS00455	COG1136	(ABC) transporter
HUT05_RS00465	COG2197	response regulator
HUT05_RS00495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT05_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS00510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS00530	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS00540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT05_RS00540	COG3320	Male sterility
HUT05_RS00555	COG2175	clavaminate synthase activity
HUT05_RS00560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUT05_RS00575	COG4974	Belongs to the 'phage' integrase family
HUT05_RS00660	COG0477	Major facilitator Superfamily
HUT05_RS00665	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HUT05_RS00675	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS00685	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS00705	COG2080	2 iron, 2 sulfur cluster binding
HUT05_RS00710	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT05_RS00715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT05_RS00725	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS00730	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS00740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT05_RS00750	COG2159	amidohydrolase
HUT05_RS00760	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT05_RS00765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT05_RS00765	COG0473	3-isopropylmalate dehydrogenase activity
HUT05_RS00770	COG1802	Transcriptional regulator
HUT05_RS00775	COG0183	Belongs to the thiolase family
HUT05_RS00780	COG1024	Enoyl-CoA hydratase
HUT05_RS00810	COG2084	Dehydrogenase
HUT05_RS00850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT05_RS00865	COG3903	Transcriptional regulator
HUT05_RS00865	COG3629	intracellular signal transduction
HUT05_RS00895	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS00905	COG1414	Transcriptional regulator
HUT05_RS00910	COG1733	regulation of RNA biosynthetic process
HUT05_RS00925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT05_RS00945	COG0367	asparagine synthase
HUT05_RS00970	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS00980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT05_RS00995	COG4310	Domain of unknown function (DUF2172)
HUT05_RS01005	COG1215	transferase activity, transferring glycosyl groups
HUT05_RS01020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT05_RS01030	COG0667	Aldo Keto reductase
HUT05_RS01040	COG0656	L-ascorbic acid biosynthetic process
HUT05_RS01050	COG1063	alcohol dehydrogenase
HUT05_RS01060	COG1595	DNA-templated transcription, initiation
HUT05_RS01095	COG2814	Major facilitator Superfamily
HUT05_RS01110	COG1309	transcriptional regulator
HUT05_RS01130	COG3321	synthase
HUT05_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS01130	COG0604	alcohol dehydrogenase
HUT05_RS01195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT05_RS01225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT05_RS01230	COG3251	PFAM MbtH domain protein
HUT05_RS01245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT05_RS01250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT05_RS01285	COG2197	response regulator
HUT05_RS01395	COG0154	amidase activity
HUT05_RS01410	COG3959	Transketolase, thiamine diphosphate binding domain
HUT05_RS01465	COG0640	Transcriptional regulator
HUT05_RS01495	COG2409	Drug exporters of the RND superfamily
HUT05_RS01500	COG4585	Histidine kinase
HUT05_RS01505	COG2197	response regulator
HUT05_RS01535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT05_RS01540	COG3284	Transcriptional regulator
HUT05_RS01560	COG0395	ABC-type sugar transport system, permease component
HUT05_RS01565	COG3842	ATPase activity
HUT05_RS01570	COG3842	ATPase activity
HUT05_RS01585	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS01610	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS01620	COG2860	membrane
HUT05_RS01760	COG2197	response regulator
HUT05_RS01770	COG1132	(ABC) transporter
HUT05_RS01775	COG1132	(ABC) transporter
HUT05_RS01785	COG0515	serine threonine protein kinase
HUT05_RS01790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT05_RS01795	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS01800	COG0583	DNA-binding transcription factor activity
HUT05_RS01830	COG0604	alcohol dehydrogenase
HUT05_RS01835	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS01840	COG0789	Transcriptional regulator
HUT05_RS01845	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS01900	COG2223	nitrite transmembrane transporter activity
HUT05_RS01910	COG0019	diaminopimelate decarboxylase activity
HUT05_RS01925	COG2188	Transcriptional regulator
HUT05_RS01960	COG0477	Major facilitator Superfamily
HUT05_RS01970	COG0483	inositol monophosphate 1-phosphatase activity
HUT05_RS01975	COG0583	DNA-binding transcription factor activity
HUT05_RS01980	COG4221	oxidoreductase activity
HUT05_RS02015	COG2409	Drug exporters of the RND superfamily
HUT05_RS02025	COG0745	RESPONSE REGULATOR receiver
HUT05_RS02030	COG5002	protein histidine kinase activity
HUT05_RS02090	COG0702	epimerase
HUT05_RS02095	COG1295	ribonuclease BN
HUT05_RS02100	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HUT05_RS02140	COG3903	Transcriptional regulator
HUT05_RS02140	COG2197	response regulator
HUT05_RS02205	COG3250	beta-galactosidase activity
HUT05_RS02220	COG4191	Histidine kinase
HUT05_RS02290	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS02310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT05_RS02320	COG3345	alpha-galactosidase
HUT05_RS02345	COG0187	DNA topoisomerase II activity
HUT05_RS02350	COG3835	regulator
HUT05_RS02370	COG4552	Acetyltransferase involved in intracellular survival and related
HUT05_RS02385	COG4977	sequence-specific DNA binding
HUT05_RS02395	COG4221	oxidoreductase activity
HUT05_RS02405	COG1609	Transcriptional regulator
HUT05_RS02420	COG0395	ABC-type sugar transport system, permease component
HUT05_RS02450	COG1175	transmembrane transport
HUT05_RS02455	COG0395	ABC-type sugar transport system, permease component
HUT05_RS02465	COG1063	alcohol dehydrogenase
HUT05_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS02515	COG0596	Alpha beta hydrolase
HUT05_RS02535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS02545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT05_RS02550	COG4521	taurine ABC transporter
HUT05_RS02560	COG2175	clavaminate synthase activity
HUT05_RS02565	COG0028	Belongs to the TPP enzyme family
HUT05_RS02585	COG0667	Aldo Keto reductase
HUT05_RS02605	COG2130	NADP-dependent
HUT05_RS02610	COG1063	alcohol dehydrogenase
HUT05_RS02645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT05_RS02645	COG2080	2 iron, 2 sulfur cluster binding
HUT05_RS02655	COG1733	regulation of RNA biosynthetic process
HUT05_RS02680	COG0659	secondary active sulfate transmembrane transporter activity
HUT05_RS02700	COG2824	Alkylphosphonate utilization operon protein PhnA
HUT05_RS02725	COG0589	response to stress
HUT05_RS02735	COG0574	Belongs to the PEP-utilizing enzyme family
HUT05_RS02735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT05_RS02790	COG1140	nitrate reductase beta subunit
HUT05_RS02835	COG0475	glutathione-regulated potassium exporter activity
HUT05_RS02850	COG2205	protein histidine kinase activity
HUT05_RS02855	COG0745	RESPONSE REGULATOR receiver
HUT05_RS02870	COG0577	efflux transmembrane transporter activity
HUT05_RS02870	COG1136	(ABC) transporter
HUT05_RS02875	COG0577	efflux transmembrane transporter activity
HUT05_RS02875	COG1136	(ABC) transporter
HUT05_RS02880	COG0287	Prephenate dehydrogenase
HUT05_RS02905	COG2124	cytochrome p450
HUT05_RS02910	COG2124	cytochrome p450
HUT05_RS02920	COG0475	glutathione-regulated potassium exporter activity
HUT05_RS02930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT05_RS02950	COG1132	(ABC) transporter
HUT05_RS02965	COG1349	DNA-binding transcription factor activity
HUT05_RS02970	COG2223	nitrite transmembrane transporter activity
HUT05_RS03010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS03020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT05_RS03035	COG0577	efflux transmembrane transporter activity
HUT05_RS03035	COG1136	(ABC) transporter
HUT05_RS03045	COG0596	Alpha beta hydrolase
HUT05_RS03055	COG0326	Molecular chaperone. Has ATPase activity
HUT05_RS03080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS03125	COG3387	PFAM Glycoside hydrolase 15-related
HUT05_RS03130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HUT05_RS03135	COG3265	gluconokinase activity
HUT05_RS03150	COG4221	oxidoreductase activity
HUT05_RS03250	COG0590	tRNA wobble adenosine to inosine editing
HUT05_RS03255	COG1309	transcriptional regulator
HUT05_RS03260	COG0300	oxidoreductase activity
HUT05_RS03270	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS03355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT05_RS03365	COG0129	dihydroxy-acid dehydratase activity
HUT05_RS03375	COG1063	alcohol dehydrogenase
HUT05_RS03395	COG2172	sigma factor antagonist activity
HUT05_RS03400	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT05_RS03405	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT05_RS03430	COG1191	sigma factor activity
HUT05_RS03460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT05_RS03500	COG1120	ATPase activity
HUT05_RS03520	COG2197	response regulator
HUT05_RS03535	COG0477	Major facilitator Superfamily
HUT05_RS03555	COG2124	cytochrome p450
HUT05_RS03575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS03595	COG3386	PFAM SMP-30 Gluconolaconase
HUT05_RS03600	COG0800	Aldolase
HUT05_RS03610	COG4948	Mandelate Racemase Muconate Lactonizing
HUT05_RS03615	COG2186	Transcriptional regulator
HUT05_RS03630	COG0395	ABC-type sugar transport system, permease component
HUT05_RS03635	COG1175	transmembrane transport
HUT05_RS03645	COG0667	Aldo Keto reductase
HUT05_RS03660	COG3739	integral membrane protein
HUT05_RS03695	COG1132	(ABC) transporter
HUT05_RS03700	COG1228	amidohydrolase
HUT05_RS03760	COG2267	carboxylic ester hydrolase activity
HUT05_RS03780	COG0477	Major facilitator Superfamily
HUT05_RS03805	COG3290	protein histidine kinase activity
HUT05_RS03820	COG1595	DNA-templated transcription, initiation
HUT05_RS03895	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS03930	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS03940	COG1609	Transcriptional regulator
HUT05_RS03950	COG1132	(ABC) transporter
HUT05_RS03955	COG0667	Aldo Keto reductase
HUT05_RS03960	COG0673	inositol 2-dehydrogenase activity
HUT05_RS03965	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS04025	COG1072	(Pantothenic acid kinase))
HUT05_RS04040	COG0395	ABC-type sugar transport system, permease component
HUT05_RS04045	COG1175	transmembrane transport
HUT05_RS04055	COG1940	carbohydrate kinase activity
HUT05_RS04105	COG0673	inositol 2-dehydrogenase activity
HUT05_RS04120	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUT05_RS04135	COG1846	Transcriptional regulator
HUT05_RS04135	COG1940	carbohydrate kinase activity
HUT05_RS04140	COG1175	transmembrane transport
HUT05_RS04145	COG0395	ABC-type sugar transport system, permease component
HUT05_RS04165	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS04175	COG4221	oxidoreductase activity
HUT05_RS04190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT05_RS04190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT05_RS04200	COG1937	Protein conserved in bacteria
HUT05_RS04210	COG1132	(ABC) transporter
HUT05_RS04235	COG0019	diaminopimelate decarboxylase activity
HUT05_RS04265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT05_RS04275	COG3345	alpha-galactosidase
HUT05_RS04300	COG0789	Transcriptional regulator
HUT05_RS04380	COG0515	serine threonine protein kinase
HUT05_RS04390	COG1132	(ABC) transporter
HUT05_RS04400	COG2197	response regulator
HUT05_RS04435	COG2274	protein secretion by the type I secretion system
HUT05_RS04440	COG3832	glyoxalase III activity
HUT05_RS04480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT05_RS04505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT05_RS04520	COG3250	beta-galactosidase activity
HUT05_RS04550	COG0667	Aldo Keto reductase
HUT05_RS04575	COG2124	cytochrome p450
HUT05_RS04600	COG0435	Glutathione S-transferase
HUT05_RS04625	COG0531	amino acid
HUT05_RS04650	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS04665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT05_RS04675	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT05_RS04680	COG1006	Multisubunit Na H antiporter MnhC subunit
HUT05_RS04725	COG1796	DNA polymerase
HUT05_RS04725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT05_RS04785	COG2706	6-phosphogluconolactonase activity
HUT05_RS04795	COG1309	transcriptional regulator
HUT05_RS04805	COG1357	PFAM Pentapeptide repeats (8 copies)
HUT05_RS04815	COG1595	DNA-templated transcription, initiation
HUT05_RS04830	COG1609	Transcriptional regulator
HUT05_RS04855	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT05_RS04860	COG1129	ABC transporter
HUT05_RS04870	COG3347	Dehydrogenase
HUT05_RS04870	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS04875	COG1070	Carbohydrate kinase
HUT05_RS04880	COG0247	lactate metabolic process
HUT05_RS04885	COG1139	Iron-sulfur cluster binding protein
HUT05_RS04890	COG1556	Lactate utilization protein
HUT05_RS04895	COG3250	beta-galactosidase activity
HUT05_RS04910	COG0577	efflux transmembrane transporter activity
HUT05_RS04910	COG1136	(ABC) transporter
HUT05_RS04925	COG0542	response to heat
HUT05_RS04940	COG0604	alcohol dehydrogenase
HUT05_RS04940	COG3321	synthase
HUT05_RS04975	COG1609	Transcriptional regulator
HUT05_RS04990	COG1121	(ABC) transporter
HUT05_RS05000	COG2135	peptidase activity
HUT05_RS05030	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS05065	COG1088	dTDP-glucose 4,6-dehydratase activity
HUT05_RS05095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT05_RS05100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT05_RS05105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT05_RS05135	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HUT05_RS05140	COG0463	Glycosyl transferase, family 2
HUT05_RS05145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT05_RS05165	COG1063	alcohol dehydrogenase
HUT05_RS05175	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HUT05_RS05200	COG0516	GMP reductase activity
HUT05_RS05200	COG0517	IMP dehydrogenase activity
HUT05_RS05215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT05_RS05225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT05_RS05225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT05_RS05255	COG3409	Peptidoglycan-binding domain 1 protein
HUT05_RS05295	COG0242	peptide deformylase activity
HUT05_RS05305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT05_RS05320	COG1609	Transcriptional regulator
HUT05_RS05335	COG0583	DNA-binding transcription factor activity
HUT05_RS05355	COG2814	Major facilitator Superfamily
HUT05_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS05430	COG3284	Transcriptional regulator
HUT05_RS05440	COG3485	protocatechuate 3,4-dioxygenase
HUT05_RS05445	COG1454	alcohol dehydrogenase
HUT05_RS05450	COG2353	YceI-like domain
HUT05_RS05460	COG2326	polyphosphate kinase activity
HUT05_RS05480	COG4948	Mandelate Racemase Muconate Lactonizing
HUT05_RS05485	COG2610	gluconate transmembrane transporter activity
HUT05_RS05530	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS05545	COG1252	NADH dehydrogenase
HUT05_RS05600	COG2197	response regulator
HUT05_RS05610	COG2197	response regulator
HUT05_RS05665	COG3321	synthase
HUT05_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS05665	COG0604	alcohol dehydrogenase
HUT05_RS05685	COG1309	transcriptional regulator
HUT05_RS05700	COG2814	Major facilitator Superfamily
HUT05_RS05740	COG1819	glycosyl
HUT05_RS05755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT05_RS05765	COG1595	DNA-templated transcription, initiation
HUT05_RS05770	COG1764	response to oxidative stress
HUT05_RS05780	COG1053	succinate dehydrogenase
HUT05_RS05790	COG1595	DNA-templated transcription, initiation
HUT05_RS05805	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS05810	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS05815	COG0300	oxidoreductase activity
HUT05_RS05840	COG2268	Band 7 protein
HUT05_RS05860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT05_RS05865	COG0121	glutamine amidotransferase
HUT05_RS05870	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT05_RS05875	COG3360	Dodecin
HUT05_RS05900	COG2226	methyltransferase
HUT05_RS05915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT05_RS05925	COG2197	response regulator
HUT05_RS05930	COG0277	FAD linked oxidase domain protein
HUT05_RS05935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS05960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT05_RS05965	COG1053	succinate dehydrogenase
HUT05_RS05975	COG0583	DNA-binding transcription factor activity
HUT05_RS05980	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS05990	COG0583	DNA-binding transcription factor activity
HUT05_RS06035	COG0726	polysaccharide deacetylase
HUT05_RS06040	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT05_RS06040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT05_RS06050	COG0596	Alpha beta hydrolase
HUT05_RS06080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT05_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS06125	COG4948	Mandelate Racemase Muconate Lactonizing
HUT05_RS06135	COG1129	ABC transporter
HUT05_RS06145	COG2186	Transcriptional regulator
HUT05_RS06170	COG0395	ABC-type sugar transport system, permease component
HUT05_RS06175	COG1175	transmembrane transport
HUT05_RS06185	COG1609	Transcriptional regulator
HUT05_RS06235	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS06255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUT05_RS06260	COG0297	glycogen (starch) synthase activity
HUT05_RS06280	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUT05_RS06285	COG2267	carboxylic ester hydrolase activity
HUT05_RS06290	COG0596	Alpha beta hydrolase
HUT05_RS06300	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT05_RS06315	COG1132	(ABC) transporter
HUT05_RS06330	COG0668	transmembrane transport
HUT05_RS06340	COG2838	Isocitrate dehydrogenase
HUT05_RS06405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT05_RS06585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS06590	COG0431	NADPH-dependent FMN reductase
HUT05_RS06600	COG1126	abc transporter atp-binding protein
HUT05_RS06605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT05_RS06615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS06620	COG0765	amino acid transport
HUT05_RS06640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT05_RS06645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT05_RS06650	COG1414	Transcriptional regulator
HUT05_RS06675	COG2814	Major facilitator Superfamily
HUT05_RS06690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT05_RS06695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT05_RS06700	COG2186	Transcriptional regulator
HUT05_RS06710	COG1609	Transcriptional regulator
HUT05_RS06715	COG0673	inositol 2-dehydrogenase activity
HUT05_RS06720	COG0673	inositol 2-dehydrogenase activity
HUT05_RS06725	COG1609	Transcriptional regulator
HUT05_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS06740	COG0673	inositol 2-dehydrogenase activity
HUT05_RS06750	COG0673	inositol 2-dehydrogenase activity
HUT05_RS06775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS06785	COG3718	enzyme involved in inositol metabolism
HUT05_RS06790	COG3962	Belongs to the TPP enzyme family
HUT05_RS06800	COG2188	Transcriptional regulator
HUT05_RS06815	COG0494	nUDIX hydrolase
HUT05_RS06820	COG0537	adenosine 5'-monophosphoramidase activity
HUT05_RS06870	COG2267	carboxylic ester hydrolase activity
HUT05_RS06895	COG0402	S-adenosylhomocysteine deaminase activity
HUT05_RS06900	COG0022	dehydrogenase e1 component
HUT05_RS06905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUT05_RS06910	COG0006	proline dipeptidase activity
HUT05_RS06930	COG0174	glutamine synthetase
HUT05_RS06945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS06950	COG3548	integral membrane protein
HUT05_RS06955	COG3469	chitinase activity
HUT05_RS06975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT05_RS06980	COG3958	Transketolase
HUT05_RS07005	COG1309	transcriptional regulator
HUT05_RS07010	COG0300	oxidoreductase activity
HUT05_RS07020	COG0402	S-adenosylhomocysteine deaminase activity
HUT05_RS07040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT05_RS07080	COG0506	proline dehydrogenase activity
HUT05_RS07105	COG1126	abc transporter atp-binding protein
HUT05_RS07160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT05_RS07175	COG2197	response regulator
HUT05_RS07185	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS07220	COG0477	Major facilitator Superfamily
HUT05_RS07235	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
HUT05_RS07240	COG4948	Mandelate Racemase Muconate Lactonizing
HUT05_RS07245	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS07255	COG1454	alcohol dehydrogenase
HUT05_RS07285	COG0583	DNA-binding transcription factor activity
HUT05_RS07290	COG0156	8-amino-7-oxononanoate synthase activity
HUT05_RS07295	COG1063	alcohol dehydrogenase
HUT05_RS07305	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS07310	COG0583	DNA-binding transcription factor activity
HUT05_RS07375	COG2755	lipolytic protein G-D-S-L family
HUT05_RS07410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT05_RS07415	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT05_RS07430	COG1657	PFAM Prenyltransferase squalene oxidase
HUT05_RS07440	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT05_RS07450	COG1562	ergosterol biosynthetic process
HUT05_RS07455	COG1134	teichoic acid transport
HUT05_RS07500	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT05_RS07515	COG1024	Enoyl-CoA hydratase
HUT05_RS07535	COG2183	response to ionizing radiation
HUT05_RS07540	COG0488	(ABC) transporter
HUT05_RS07550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT05_RS07560	COG2936	dipeptidyl-peptidase activity
HUT05_RS07570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS07580	COG1113	amino acid transport
HUT05_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS07595	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT05_RS07605	COG1129	ABC transporter
HUT05_RS07615	COG1414	Transcriptional regulator
HUT05_RS07625	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT05_RS07625	COG1024	Enoyl-CoA hydratase
HUT05_RS07630	COG0183	Belongs to the thiolase family
HUT05_RS07640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT05_RS07650	COG3268	Saccharopine dehydrogenase
HUT05_RS07685	COG0488	(ABC) transporter
HUT05_RS07690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT05_RS07695	COG1834	amidinotransferase
HUT05_RS07785	COG1793	dna ligase
HUT05_RS07820	COG3485	protocatechuate 3,4-dioxygenase
HUT05_RS07825	COG3485	protocatechuate 3,4-dioxygenase
HUT05_RS07830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT05_RS07835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT05_RS07845	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT05_RS07845	COG1672	PFAM Archaeal ATPase
HUT05_RS07855	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUT05_RS07880	COG3511	phospholipase C
HUT05_RS07920	COG0596	Alpha beta hydrolase
HUT05_RS07930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT05_RS07935	COG0537	adenosine 5'-monophosphoramidase activity
HUT05_RS07940	COG1802	Transcriptional regulator
HUT05_RS07945	COG2084	Dehydrogenase
HUT05_RS07960	COG0129	dihydroxy-acid dehydratase activity
HUT05_RS07975	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT05_RS08000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT05_RS08000	COG0519	Catalyzes the synthesis of GMP from XMP
HUT05_RS08005	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS08020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT05_RS08035	COG3547	Transposase (IS116 IS110 IS902 family)
HUT05_RS08065	COG2255	four-way junction helicase activity
HUT05_RS08075	COG0702	epimerase
HUT05_RS08080	COG1733	regulation of RNA biosynthetic process
HUT05_RS08090	COG3958	Transketolase
HUT05_RS08095	COG3959	Transketolase, thiamine diphosphate binding domain
HUT05_RS08100	COG2084	Dehydrogenase
HUT05_RS08125	COG0477	Major facilitator Superfamily
HUT05_RS08145	COG0202	RNA polymerase activity
HUT05_RS08170	COG0028	Belongs to the TPP enzyme family
HUT05_RS08175	COG3848	Pyruvate phosphate dikinase
HUT05_RS08175	COG0574	Belongs to the PEP-utilizing enzyme family
HUT05_RS08180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT05_RS08200	COG1011	Hydrolase
HUT05_RS08230	COG1414	Transcriptional regulator
HUT05_RS08240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT05_RS08245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT05_RS08260	COG0366	Alpha amylase catalytic
HUT05_RS08265	COG0395	ABC-type sugar transport system, permease component
HUT05_RS08270	COG1175	transmembrane transport
HUT05_RS08295	COG3938	Belongs to the proline racemase family
HUT05_RS08300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT05_RS08315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT05_RS08370	COG3469	chitinase activity
HUT05_RS08385	COG1486	melibiose metabolic process
HUT05_RS08395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS08405	COG1175	transmembrane transport
HUT05_RS08410	COG0395	ABC-type sugar transport system, permease component
HUT05_RS08415	COG3250	beta-galactosidase activity
HUT05_RS08420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUT05_RS08440	COG3629	intracellular signal transduction
HUT05_RS08440	COG3903	Transcriptional regulator
HUT05_RS08450	COG2746	aminoglycoside 3-N-acetyltransferase activity
HUT05_RS08455	COG0641	radical SAM
HUT05_RS08490	COG4585	Histidine kinase
HUT05_RS08495	COG2197	response regulator
HUT05_RS08500	COG2409	Drug exporters of the RND superfamily
HUT05_RS08535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT05_RS08550	COG0166	Belongs to the GPI family
HUT05_RS08555	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT05_RS08560	COG0406	alpha-ribazole phosphatase activity
HUT05_RS08580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT05_RS08590	COG0477	Major facilitator Superfamily
HUT05_RS08605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT05_RS08615	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS08630	COG0346	lactoylglutathione lyase activity
HUT05_RS08635	COG3467	pyridoxamine 5'-phosphate
HUT05_RS08645	COG0477	Major facilitator Superfamily
HUT05_RS08675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT05_RS08690	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS08715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT05_RS08720	COG0747	negative chemotaxis
HUT05_RS08775	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT05_RS08780	COG0714	Associated with various cellular activities
HUT05_RS08795	COG2723	6-phospho-beta-galactosidase activity
HUT05_RS08800	COG0395	ABC-type sugar transport system, permease component
HUT05_RS08805	COG1175	transmembrane transport
HUT05_RS08810	COG2182	Extracellular solute-binding protein
HUT05_RS08820	COG3848	Pyruvate phosphate dikinase
HUT05_RS08820	COG0574	Belongs to the PEP-utilizing enzyme family
HUT05_RS08825	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT05_RS08850	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS08860	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT05_RS08870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT05_RS08880	COG2223	nitrite transmembrane transporter activity
HUT05_RS08940	COG0673	inositol 2-dehydrogenase activity
HUT05_RS08950	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT05_RS08955	COG1129	ABC transporter
HUT05_RS08960	COG1940	carbohydrate kinase activity
HUT05_RS08975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT05_RS08985	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUT05_RS08990	COG3383	formate dehydrogenase (NAD+) activity
HUT05_RS09005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT05_RS09040	COG0477	Major facilitator Superfamily
HUT05_RS09050	COG3250	beta-galactosidase activity
HUT05_RS09075	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
HUT05_RS09085	COG0656	L-ascorbic acid biosynthetic process
HUT05_RS09105	COG4106	trans-aconitate 2-methyltransferase activity
HUT05_RS09115	COG5297	Belongs to the glycosyl hydrolase family 6
HUT05_RS09125	COG4733	cellulase activity
HUT05_RS09125	COG5297	Belongs to the glycosyl hydrolase family 6
HUT05_RS09135	COG2814	Major facilitator Superfamily
HUT05_RS09140	COG1846	Transcriptional regulator
HUT05_RS09145	COG3401	FG-GAP repeat protein
HUT05_RS09150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT05_RS09150	COG4106	trans-aconitate 2-methyltransferase activity
HUT05_RS09155	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT05_RS09185	COG1140	nitrate reductase beta subunit
HUT05_RS09200	COG0443	Heat shock 70 kDa protein
HUT05_RS09275	COG0028	Belongs to the TPP enzyme family
HUT05_RS09290	COG1846	Transcriptional regulator
HUT05_RS09310	COG0693	protein deglycase activity
HUT05_RS09320	COG0488	(ABC) transporter
HUT05_RS09325	COG0406	alpha-ribazole phosphatase activity
HUT05_RS09395	COG3285	dna ligase
HUT05_RS09395	COG1793	dna ligase
HUT05_RS09410	COG4948	Mandelate Racemase Muconate Lactonizing
HUT05_RS09445	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT05_RS09450	COG4946	Tricorn protease homolog
HUT05_RS09450	COG0823	Involved in the tonB-independent uptake of proteins
HUT05_RS09450	COG1506	peptidase
HUT05_RS09455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS09465	COG0310	cobalt ion transport
HUT05_RS09470	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HUT05_RS09485	COG1122	ATPase activity
HUT05_RS09510	COG5297	Belongs to the glycosyl hydrolase family 6
HUT05_RS09510	COG3250	beta-galactosidase activity
HUT05_RS09515	COG2226	methyltransferase
HUT05_RS09565	COG1476	TRANSCRIPTIONal
HUT05_RS09630	COG2267	carboxylic ester hydrolase activity
HUT05_RS09650	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS09660	COG1522	sequence-specific DNA binding
HUT05_RS09685	COG2197	response regulator
HUT05_RS09690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT05_RS09695	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT05_RS09710	COG1024	Enoyl-CoA hydratase
HUT05_RS09715	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS09745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS09745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS09750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS09755	COG1119	ATPase activity
HUT05_RS09770	COG0477	Major facilitator Superfamily
HUT05_RS09845	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS09850	COG1309	transcriptional regulator
HUT05_RS09935	COG0596	Alpha beta hydrolase
HUT05_RS09955	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT05_RS09970	COG0604	alcohol dehydrogenase
HUT05_RS09975	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS09975	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS09995	COG0688	phosphatidylethanolamine metabolic process
HUT05_RS10005	COG1929	Belongs to the glycerate kinase type-1 family
HUT05_RS10020	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT05_RS10060	COG0640	Transcriptional regulator
HUT05_RS10080	COG2267	carboxylic ester hydrolase activity
HUT05_RS10085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT05_RS10145	COG2318	DinB family
HUT05_RS10200	COG0483	inositol monophosphate 1-phosphatase activity
HUT05_RS10235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT05_RS10270	COG2197	response regulator
HUT05_RS10275	COG3851	Histidine kinase
HUT05_RS10290	COG1953	Uracil, thiamine, allantoin
HUT05_RS10305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT05_RS10365	COG1132	(ABC) transporter
HUT05_RS10370	COG0542	response to heat
HUT05_RS10375	COG0405	Gamma-glutamyltransferase
HUT05_RS10385	COG2936	dipeptidyl-peptidase activity
HUT05_RS10410	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT05_RS10425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT05_RS10435	COG1940	carbohydrate kinase activity
HUT05_RS10440	COG2188	Transcriptional regulator
HUT05_RS10445	COG0673	inositol 2-dehydrogenase activity
HUT05_RS10455	COG2197	response regulator
HUT05_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS10495	COG4266	Belongs to the allantoicase family
HUT05_RS10500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT05_RS10505	COG1414	Transcriptional regulator
HUT05_RS10545	COG4264	IucA IucC family
HUT05_RS10565	COG0436	Aminotransferase
HUT05_RS10575	COG0406	alpha-ribazole phosphatase activity
HUT05_RS10590	COG1733	regulation of RNA biosynthetic process
HUT05_RS10600	COG0702	epimerase
HUT05_RS10610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT05_RS10610	COG0515	serine threonine protein kinase
HUT05_RS10620	COG2233	PERMEase
HUT05_RS10635	COG2351	hydroxyisourate hydrolase activity
HUT05_RS10655	COG0309	Hydrogenase expression formation protein (HypE)
HUT05_RS10665	COG0298	carbon dioxide binding
HUT05_RS10670	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HUT05_RS10675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT05_RS10680	COG0375	protein maturation
HUT05_RS10710	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HUT05_RS10720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT05_RS10720	COG1024	Enoyl-CoA hydratase
HUT05_RS10735	COG3622	Belongs to the hyi family
HUT05_RS10740	COG2084	Dehydrogenase
HUT05_RS10745	COG0753	catalase activity
HUT05_RS10755	COG3960	tartronate-semialdehyde synthase activity
HUT05_RS10770	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS10775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT05_RS10780	COG2197	response regulator
HUT05_RS10805	COG0598	Magnesium transport protein CorA
HUT05_RS10820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT05_RS10850	COG2197	response regulator
HUT05_RS10865	COG0583	DNA-binding transcription factor activity
HUT05_RS10890	COG3290	protein histidine kinase activity
HUT05_RS10920	COG0444	Belongs to the ABC transporter superfamily
HUT05_RS10925	COG4172	Belongs to the ABC transporter superfamily
HUT05_RS10930	COG3940	Belongs to the glycosyl hydrolase 43 family
HUT05_RS10935	COG3940	Belongs to the glycosyl hydrolase 43 family
HUT05_RS10945	COG5634	Uncharacterized conserved protein (DUF2278)
HUT05_RS10965	COG2252	PERMEase
HUT05_RS10970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT05_RS10985	COG3835	regulator
HUT05_RS10995	COG1802	Transcriptional regulator
HUT05_RS11030	COG1404	Belongs to the peptidase S8 family
HUT05_RS11050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT05_RS11060	COG1162	GTPase activity
HUT05_RS11080	COG3903	Transcriptional regulator
HUT05_RS11080	COG3629	intracellular signal transduction
HUT05_RS11100	COG0277	FAD linked oxidase domain protein
HUT05_RS11120	COG1175	transmembrane transport
HUT05_RS11135	COG1131	(ABC) transporter
HUT05_RS11185	COG1136	(ABC) transporter
HUT05_RS11190	COG4585	Histidine kinase
HUT05_RS11195	COG2197	response regulator
HUT05_RS11215	COG0494	nUDIX hydrolase
HUT05_RS11235	COG2755	lipolytic protein G-D-S-L family
HUT05_RS11255	COG2040	homocysteine
HUT05_RS11275	COG3629	intracellular signal transduction
HUT05_RS11275	COG3903	Transcriptional regulator
HUT05_RS11305	COG4977	sequence-specific DNA binding
HUT05_RS11305	COG1917	Cupin 2, conserved barrel domain protein
HUT05_RS11320	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS11350	COG0175	sulfate reduction
HUT05_RS11355	COG0529	Catalyzes the synthesis of activated sulfate
HUT05_RS11380	COG1116	anion transmembrane transporter activity
HUT05_RS11385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT05_RS11400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUT05_RS11435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT05_RS11450	COG1175	transmembrane transport
HUT05_RS11460	COG0583	DNA-binding transcription factor activity
HUT05_RS11545	COG1280	lysine exporter protein (LysE YggA)
HUT05_RS11550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT05_RS11560	COG0504	CTP synthase activity
HUT05_RS11585	COG1116	anion transmembrane transporter activity
HUT05_RS11585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT05_RS11590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT05_RS11600	COG2358	TRAP transporter, solute receptor (TAXI family
HUT05_RS11630	COG1404	Belongs to the peptidase S8 family
HUT05_RS11715	COG1846	Transcriptional regulator
HUT05_RS11715	COG1940	carbohydrate kinase activity
HUT05_RS11735	COG2018	Roadblock/LC7 domain
HUT05_RS11755	COG1174	glycine betaine transport
HUT05_RS11795	COG0745	RESPONSE REGULATOR receiver
HUT05_RS11800	COG5002	protein histidine kinase activity
HUT05_RS11810	COG5002	protein histidine kinase activity
HUT05_RS11815	COG0745	RESPONSE REGULATOR receiver
HUT05_RS11865	COG4172	Belongs to the ABC transporter superfamily
HUT05_RS11870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT05_RS11880	COG0747	negative chemotaxis
HUT05_RS11900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT05_RS11920	COG3284	Transcriptional regulator
HUT05_RS11925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT05_RS11935	COG1073	alpha beta
HUT05_RS11940	COG0596	Alpha beta hydrolase
HUT05_RS11955	COG4821	SIS domain
HUT05_RS11960	COG1737	Transcriptional regulator
HUT05_RS11970	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT05_RS11985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT05_RS11990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT05_RS12025	COG0330	HflC and HflK could
HUT05_RS12050	COG1121	(ABC) transporter
HUT05_RS12060	COG3220	belongs to the UPF0276 family
HUT05_RS12095	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT05_RS12110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT05_RS12125	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HUT05_RS12130	COG3833	ABC-type maltose transport systems, permease component
HUT05_RS12135	COG1175	transmembrane transport
HUT05_RS12145	COG3250	beta-galactosidase activity
HUT05_RS12150	COG1609	Transcriptional regulator
HUT05_RS12155	COG0183	Belongs to the thiolase family
HUT05_RS12160	COG1024	Enoyl-CoA hydratase
HUT05_RS12160	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT05_RS12195	COG0531	amino acid
HUT05_RS12200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT05_RS12205	COG4214	carbohydrate transport
HUT05_RS12215	COG4213	ABC transporter substrate-binding protein
HUT05_RS12220	COG1940	carbohydrate kinase activity
HUT05_RS12225	COG0395	ABC-type sugar transport system, permease component
HUT05_RS12230	COG1175	transmembrane transport
HUT05_RS12235	COG1653	transport
HUT05_RS12245	COG3537	Alpha-1,2-mannosidase
HUT05_RS12285	COG2205	protein histidine kinase activity
HUT05_RS12290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUT05_RS12295	COG0137	argininosuccinate synthase activity
HUT05_RS12305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT05_RS12325	COG1940	carbohydrate kinase activity
HUT05_RS12335	COG2207	Transcriptional regulator
HUT05_RS12340	COG2205	protein histidine kinase activity
HUT05_RS12345	COG3119	arylsulfatase activity
HUT05_RS12345	COG3408	Glycogen debranching enzyme
HUT05_RS12380	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HUT05_RS12395	COG2267	carboxylic ester hydrolase activity
HUT05_RS12415	COG1414	Transcriptional regulator
HUT05_RS12420	COG3971	2-oxopent-4-enoate hydratase activity
HUT05_RS12425	COG4569	acetaldehyde dehydrogenase (acetylating) activity
HUT05_RS12430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT05_RS12465	COG0529	Catalyzes the synthesis of activated sulfate
HUT05_RS12485	COG1024	Enoyl-CoA hydratase
HUT05_RS12495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT05_RS12500	COG2235	arginine
HUT05_RS12515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT05_RS12545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT05_RS12550	COG1799	cell septum assembly
HUT05_RS12555	COG0243	molybdopterin cofactor binding
HUT05_RS12575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT05_RS12585	COG1140	nitrate reductase beta subunit
HUT05_RS12635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT05_RS12635	COG0426	domain, Protein
HUT05_RS12645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT05_RS12655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS12660	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT05_RS12675	COG4221	oxidoreductase activity
HUT05_RS12745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT05_RS12750	COG0531	amino acid
HUT05_RS12755	COG0569	domain protein
HUT05_RS12795	COG0756	dUTP diphosphatase activity
HUT05_RS12820	COG2205	protein histidine kinase activity
HUT05_RS12825	COG0745	RESPONSE REGULATOR receiver
HUT05_RS12870	COG1435	thymidine kinase activity
HUT05_RS12890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT05_RS12895	COG1802	Transcriptional regulator
HUT05_RS12910	COG0612	Peptidase, M16
HUT05_RS12915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT05_RS12920	COG0523	cobalamin synthesis protein
HUT05_RS12940	COG3290	protein histidine kinase activity
HUT05_RS12945	COG4565	transcriptional regulatory protein
HUT05_RS12950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT05_RS12960	COG0187	DNA topoisomerase II activity
HUT05_RS12975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT05_RS12980	COG1802	Transcriptional regulator
HUT05_RS13020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT05_RS13040	COG0588	phosphoglycerate mutase activity
HUT05_RS13055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT05_RS13060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT05_RS13065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT05_RS13100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT05_RS13110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT05_RS13115	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT05_RS13125	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT05_RS13150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT05_RS13160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT05_RS13170	COG0604	alcohol dehydrogenase
HUT05_RS13170	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS13170	COG3321	synthase
HUT05_RS13180	COG2358	TRAP transporter, solute receptor (TAXI family
HUT05_RS13185	COG2205	protein histidine kinase activity
HUT05_RS13190	COG0745	RESPONSE REGULATOR receiver
HUT05_RS13195	COG1126	abc transporter atp-binding protein
HUT05_RS13200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT05_RS13205	COG0765	amino acid transport
HUT05_RS13210	COG0765	amino acid transport
HUT05_RS13235	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT05_RS13245	COG1396	sequence-specific DNA binding
HUT05_RS13255	COG0628	permease
HUT05_RS13280	COG2207	Transcriptional regulator
HUT05_RS13280	COG1917	Cupin 2, conserved barrel domain protein
HUT05_RS13285	COG1201	RNA secondary structure unwinding
HUT05_RS13290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT05_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS13305	COG1396	sequence-specific DNA binding
HUT05_RS13310	COG1546	Belongs to the CinA family
HUT05_RS13310	COG1058	Belongs to the CinA family
HUT05_RS13320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT05_RS13330	COG1674	ftsk spoiiie
HUT05_RS13340	COG2205	protein histidine kinase activity
HUT05_RS13340	COG4999	Histidine kinase
HUT05_RS13340	COG3850	Histidine kinase
HUT05_RS13340	COG3437	response regulator, receiver
HUT05_RS13345	COG2208	phosphoserine phosphatase activity
HUT05_RS13345	COG2770	Histidine kinase
HUT05_RS13375	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT05_RS13380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT05_RS13385	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HUT05_RS13405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT05_RS13410	COG0612	Peptidase, M16
HUT05_RS13415	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT05_RS13420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT05_RS13430	COG1674	ftsk spoiiie
HUT05_RS13545	COG1404	Belongs to the peptidase S8 family
HUT05_RS13570	COG1404	Belongs to the peptidase S8 family
HUT05_RS13600	COG0455	bacterial-type flagellum organization
HUT05_RS13620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUT05_RS13625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT05_RS13635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT05_RS13650	COG0779	Required for maturation of 30S ribosomal subunits
HUT05_RS13700	COG0442	prolyl-tRNA aminoacylation
HUT05_RS13715	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT05_RS13720	COG0750	zinc metalloprotease
HUT05_RS13725	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUT05_RS13770	COG0395	ABC-type sugar transport system, permease component
HUT05_RS13775	COG4209	transmembrane transport
HUT05_RS13780	COG1653	transport
HUT05_RS13790	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS13825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT05_RS13830	COG1177	transmembrane transport
HUT05_RS13835	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT05_RS13840	COG3842	ATPase activity
HUT05_RS13865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT05_RS13870	COG0584	glycerophosphoryl diester phosphodiesterase
HUT05_RS13880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT05_RS13895	COG2815	serine threonine protein kinase
HUT05_RS13895	COG0515	serine threonine protein kinase
HUT05_RS14010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT05_RS14015	COG1115	amino acid carrier protein
HUT05_RS14015	COG1115	amino acid carrier protein
HUT05_RS14050	COG1595	DNA-templated transcription, initiation
HUT05_RS14085	COG1595	DNA-templated transcription, initiation
HUT05_RS14095	COG0009	L-threonylcarbamoyladenylate synthase
HUT05_RS14145	COG2856	Zn peptidase
HUT05_RS14165	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS14175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT05_RS14180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT05_RS14205	COG0513	Belongs to the DEAD box helicase family
HUT05_RS14210	COG1278	Cold shock
HUT05_RS14220	COG3842	ATPase activity
HUT05_RS14225	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HUT05_RS14235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT05_RS14245	COG0575	Belongs to the CDS family
HUT05_RS14250	COG0233	cytoplasmic translational termination
HUT05_RS14255	COG0528	UMP kinase activity
HUT05_RS14260	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT05_RS14265	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT05_RS14270	COG4942	peptidase
HUT05_RS14280	COG1191	sigma factor activity
HUT05_RS14295	COG0792	nuclease activity
HUT05_RS14315	COG0681	Belongs to the peptidase S26 family
HUT05_RS14330	COG0335	large ribosomal subunit rRNA binding
HUT05_RS14335	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT05_RS14340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT05_RS14345	COG1837	Belongs to the UPF0109 family
HUT05_RS14350	COG0228	four-way junction DNA binding
HUT05_RS14360	COG0442	prolyl-tRNA aminoacylation
HUT05_RS14370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT05_RS14380	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT05_RS14415	COG0477	Major facilitator Superfamily
HUT05_RS14420	COG1196	nuclear chromosome segregation
HUT05_RS14430	COG1254	Belongs to the acylphosphatase family
HUT05_RS14435	COG2340	Cysteine-rich secretory protein family
HUT05_RS14440	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUT05_RS14445	COG1733	regulation of RNA biosynthetic process
HUT05_RS14450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT05_RS14455	COG0571	ribonuclease III activity
HUT05_RS14460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT05_RS14475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT05_RS14480	COG0742	ribosomal rna small subunit methyltransferase
HUT05_RS14490	COG0326	Molecular chaperone. Has ATPase activity
HUT05_RS14500	COG1461	Dihydroxyacetone kinase
HUT05_RS14505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT05_RS14510	COG0351	phosphomethylpyrimidine kinase
HUT05_RS14530	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT05_RS14535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT05_RS14545	COG1920	GTP binding
HUT05_RS14555	COG0776	regulation of translation
HUT05_RS14565	COG0066	3-isopropylmalate dehydratase activity
HUT05_RS14570	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT05_RS14575	COG1414	Transcriptional regulator
HUT05_RS14625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT05_RS14630	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT05_RS14640	COG5002	protein histidine kinase activity
HUT05_RS14645	COG2018	Roadblock/LC7 domain
HUT05_RS14665	COG2018	Roadblock/LC7 domain
HUT05_RS14685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT05_RS14690	COG5492	domain, Protein
HUT05_RS14695	COG2353	YceI-like domain
HUT05_RS14740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT05_RS14755	COG2957	Belongs to the agmatine deiminase family
HUT05_RS14760	COG0804	urea catabolic process
HUT05_RS14765	COG0831	urea catabolic process
HUT05_RS14765	COG0832	Belongs to the urease beta subunit family
HUT05_RS14775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT05_RS14780	COG0473	3-isopropylmalate dehydrogenase activity
HUT05_RS14805	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS14810	COG0506	proline dehydrogenase activity
HUT05_RS14815	COG3835	regulator
HUT05_RS14830	COG0477	Major facilitator Superfamily
HUT05_RS14840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT05_RS14845	COG0440	acetolactate synthase activity
HUT05_RS14855	COG5001	Diguanylate cyclase
HUT05_RS14865	COG0667	Aldo Keto reductase
HUT05_RS14870	COG2133	pyrroloquinoline quinone binding
HUT05_RS14880	COG2197	response regulator
HUT05_RS14895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT05_RS14900	COG2409	Drug exporters of the RND superfamily
HUT05_RS14910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT05_RS14915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT05_RS14925	COG0154	amidase activity
HUT05_RS14930	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT05_RS14955	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT05_RS14965	COG4221	oxidoreductase activity
HUT05_RS14970	COG1611	Belongs to the LOG family
HUT05_RS14985	COG0482	sulfurtransferase activity
HUT05_RS15025	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT05_RS15030	COG2860	membrane
HUT05_RS15035	COG4608	Belongs to the ABC transporter superfamily
HUT05_RS15055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT05_RS15075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT05_RS15080	COG0509	glycine decarboxylation via glycine cleavage system
HUT05_RS15085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT05_RS15150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT05_RS15350	COG2188	Transcriptional regulator
HUT05_RS15360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT05_RS15360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT05_RS15445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT05_RS15450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT05_RS15455	COG1760	l-serine dehydratase
HUT05_RS15495	COG1376	ErfK ybiS ycfS ynhG family protein
HUT05_RS15500	COG1376	ErfK ybiS ycfS ynhG family protein
HUT05_RS15510	COG3119	arylsulfatase activity
HUT05_RS15515	COG2197	response regulator
HUT05_RS15520	COG4585	Histidine kinase
HUT05_RS15530	COG1131	(ABC) transporter
HUT05_RS15535	COG1132	(ABC) transporter
HUT05_RS15540	COG1132	(ABC) transporter
HUT05_RS15545	COG1132	(ABC) transporter
HUT05_RS15550	COG1132	(ABC) transporter
HUT05_RS15575	COG0058	SHG alpha-glucan phosphorylase activity
HUT05_RS15625	COG4689	acetoacetate decarboxylase
HUT05_RS15630	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS15640	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT05_RS15655	COG4689	acetoacetate decarboxylase
HUT05_RS15660	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS15670	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT05_RS15685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT05_RS15705	COG1522	sequence-specific DNA binding
HUT05_RS15715	COG0667	Aldo Keto reductase
HUT05_RS15720	COG1301	dicarboxylic acid transport
HUT05_RS15725	COG3290	protein histidine kinase activity
HUT05_RS15730	COG4565	transcriptional regulatory protein
HUT05_RS15740	COG1175	transmembrane transport
HUT05_RS15745	COG0395	ABC-type sugar transport system, permease component
HUT05_RS15750	COG0259	pyridoxamine-phosphate oxidase activity
HUT05_RS15760	COG0205	6-phosphofructokinase activity
HUT05_RS15765	COG0280	phosphate acetyltransferase
HUT05_RS15765	COG0857	belongs to the CobB CobQ family
HUT05_RS15770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUT05_RS15805	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS15805	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS15820	COG2329	Antibiotic biosynthesis monooxygenase
HUT05_RS15825	COG2124	cytochrome p450
HUT05_RS15835	COG2159	amidohydrolase
HUT05_RS15910	COG3850	Histidine kinase
HUT05_RS15910	COG0642	Histidine kinase
HUT05_RS15915	COG0745	RESPONSE REGULATOR receiver
HUT05_RS15935	COG0183	Belongs to the thiolase family
HUT05_RS15940	COG0346	lactoylglutathione lyase activity
HUT05_RS15955	COG1131	(ABC) transporter
HUT05_RS15990	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HUT05_RS16005	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT05_RS16035	COG4585	Histidine kinase
HUT05_RS16040	COG2197	response regulator
HUT05_RS16055	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT05_RS16060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT05_RS16065	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT05_RS16070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUT05_RS16075	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT05_RS16080	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT05_RS16085	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT05_RS16100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT05_RS16105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT05_RS16110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT05_RS16120	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT05_RS16125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUT05_RS16130	COG0254	rRNA binding
HUT05_RS16150	COG0083	homoserine kinase activity
HUT05_RS16155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT05_RS16160	COG0460	homoserine dehydrogenase
HUT05_RS16165	COG0019	diaminopimelate decarboxylase activity
HUT05_RS16170	COG0018	arginyl-trna synthetase
HUT05_RS16210	COG2814	Major facilitator Superfamily
HUT05_RS16215	COG3251	PFAM MbtH domain protein
HUT05_RS16220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT05_RS16235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT05_RS16235	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUT05_RS16255	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT05_RS16260	COG1793	dna ligase
HUT05_RS16260	COG3285	dna ligase
HUT05_RS16280	COG2205	protein histidine kinase activity
HUT05_RS16335	COG0791	NLP P60 protein
HUT05_RS16380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT05_RS16395	COG0745	RESPONSE REGULATOR receiver
HUT05_RS16400	COG2205	protein histidine kinase activity
HUT05_RS16435	COG2319	Wd-40 repeat
HUT05_RS16435	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT05_RS16455	COG3293	Transposase
HUT05_RS16465	COG1192	Involved in chromosome partitioning
HUT05_RS16480	COG1192	Involved in chromosome partitioning
HUT05_RS16505	COG1192	Involved in chromosome partitioning
HUT05_RS16600	COG0776	regulation of translation
HUT05_RS16605	COG1278	Cold shock
HUT05_RS16640	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT05_RS16640	COG0567	Dehydrogenase, E1 component
HUT05_RS16680	COG0604	alcohol dehydrogenase
HUT05_RS16685	COG0281	malic enzyme
HUT05_RS16710	COG1595	DNA-templated transcription, initiation
HUT05_RS16715	COG4106	trans-aconitate 2-methyltransferase activity
HUT05_RS16820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT05_RS16830	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUT05_RS16860	COG1597	lipid kinase activity
HUT05_RS16875	COG1309	transcriptional regulator
HUT05_RS16880	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS16885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT05_RS16890	COG0363	glucosamine-6-phosphate deaminase activity
HUT05_RS16900	COG1476	TRANSCRIPTIONal
HUT05_RS16905	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT05_RS16910	COG0395	ABC-type sugar transport system, permease component
HUT05_RS16915	COG1175	transmembrane transport
HUT05_RS16920	COG2182	Extracellular solute-binding protein
HUT05_RS16925	COG2188	Transcriptional regulator
HUT05_RS16930	COG1966	Carbon starvation protein
HUT05_RS16975	COG2124	cytochrome p450
HUT05_RS16985	COG0242	peptide deformylase activity
HUT05_RS17000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUT05_RS17000	COG2199	diguanylate cyclase activity
HUT05_RS17005	COG5662	AntiSigma factor
HUT05_RS17010	COG1595	DNA-templated transcription, initiation
HUT05_RS17020	COG2135	peptidase activity
HUT05_RS17045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT05_RS17050	COG1162	GTPase activity
HUT05_RS17065	COG0483	inositol monophosphate 1-phosphatase activity
HUT05_RS17075	COG0753	catalase activity
HUT05_RS17115	COG1615	UPF0182 protein
HUT05_RS17125	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUT05_RS17180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT05_RS17220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS17225	COG0210	DNA helicase
HUT05_RS17250	COG0596	Alpha beta hydrolase
HUT05_RS17280	COG4172	Belongs to the ABC transporter superfamily
HUT05_RS17290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT05_RS17295	COG4166	transmembrane transport
HUT05_RS17335	COG0513	Belongs to the DEAD box helicase family
HUT05_RS17340	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HUT05_RS17345	COG1432	Conserved Protein
HUT05_RS17355	COG2095	MarC family integral membrane protein
HUT05_RS17370	COG2814	Major facilitator Superfamily
HUT05_RS17380	COG0598	Magnesium transport protein CorA
HUT05_RS17415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT05_RS17430	COG1595	DNA-templated transcription, initiation
HUT05_RS17445	COG1024	Enoyl-CoA hydratase
HUT05_RS17450	COG2818	Glycosylase
HUT05_RS17460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUT05_RS17465	COG1611	Belongs to the LOG family
HUT05_RS17470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS17505	COG2197	response regulator
HUT05_RS17510	COG4585	Histidine kinase
HUT05_RS17520	COG1131	(ABC) transporter
HUT05_RS17535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT05_RS17550	COG4608	Belongs to the ABC transporter superfamily
HUT05_RS17560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT05_RS17565	COG0601	transmembrane transport
HUT05_RS17580	COG0747	negative chemotaxis
HUT05_RS17585	COG0601	transmembrane transport
HUT05_RS17590	COG0444	Belongs to the ABC transporter superfamily
HUT05_RS17595	COG4608	Belongs to the ABC transporter superfamily
HUT05_RS17610	COG0346	lactoylglutathione lyase activity
HUT05_RS17620	COG4608	Belongs to the ABC transporter superfamily
HUT05_RS17625	COG0444	Belongs to the ABC transporter superfamily
HUT05_RS17630	COG0601	transmembrane transport
HUT05_RS17640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT05_RS17665	COG1053	succinate dehydrogenase
HUT05_RS17725	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS17730	COG0583	DNA-binding transcription factor activity
HUT05_RS17750	COG0012	GTP binding
HUT05_RS17765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT05_RS17770	COG1570	exodeoxyribonuclease VII activity
HUT05_RS17775	COG1722	exodeoxyribonuclease VII activity
HUT05_RS17780	COG0778	Nitroreductase
HUT05_RS17805	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT05_RS17805	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT05_RS17810	COG0114	fumarate hydratase activity
HUT05_RS17825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT05_RS17845	COG1136	(ABC) transporter
HUT05_RS17875	COG0450	alkyl hydroperoxide reductase
HUT05_RS17880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT05_RS17890	COG0741	lytic transglycosylase activity
HUT05_RS17895	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT05_RS17900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT05_RS17950	COG3511	phospholipase C
HUT05_RS18020	COG0765	amino acid transport
HUT05_RS18055	COG2318	DinB family
HUT05_RS18075	COG2885	chlorophyll binding
HUT05_RS18095	COG2197	response regulator
HUT05_RS18100	COG3850	Histidine kinase
HUT05_RS18130	COG2894	cell division
HUT05_RS18195	COG2610	gluconate transmembrane transporter activity
HUT05_RS18205	COG1414	Transcriptional regulator
HUT05_RS18220	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT05_RS18235	COG0436	Aminotransferase
HUT05_RS18270	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUT05_RS18280	COG0477	Major facilitator Superfamily
HUT05_RS18285	COG1309	transcriptional regulator
HUT05_RS18315	COG1331	Highly conserved protein containing a thioredoxin domain
HUT05_RS18320	COG2255	four-way junction helicase activity
HUT05_RS18330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT05_RS18340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT05_RS18360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT05_RS18365	COG2255	four-way junction helicase activity
HUT05_RS18370	COG1595	DNA-templated transcription, initiation
HUT05_RS18390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT05_RS18455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT05_RS18525	COG4941	Belongs to the sigma-70 factor family
HUT05_RS18530	COG3795	YCII-related domain
HUT05_RS18535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT05_RS18565	COG1404	Belongs to the peptidase S8 family
HUT05_RS18570	COG1136	(ABC) transporter
HUT05_RS18600	COG2986	histidine ammonia-lyase
HUT05_RS18610	COG1024	Enoyl-CoA hydratase
HUT05_RS18620	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT05_RS18630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT05_RS18645	COG0424	maF-like protein
HUT05_RS18655	COG4770	biotin carboxylase activity
HUT05_RS18660	COG4770	biotin carboxylase activity
HUT05_RS18690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT05_RS18705	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS18725	COG1595	DNA-templated transcription, initiation
HUT05_RS18730	COG0745	RESPONSE REGULATOR receiver
HUT05_RS18735	COG2205	protein histidine kinase activity
HUT05_RS18760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT05_RS18770	COG0583	DNA-binding transcription factor activity
HUT05_RS18775	COG2814	Major facilitator Superfamily
HUT05_RS18825	COG1744	ABC transporter substrate-binding protein PnrA-like
HUT05_RS18830	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT05_RS18830	COG1473	amidohydrolase
HUT05_RS18835	COG2226	methyltransferase
HUT05_RS18845	COG2089	acid synthase
HUT05_RS18860	COG1216	Glycosyl transferase, family 2
HUT05_RS18880	COG1216	Glycosyl transferase, family 2
HUT05_RS18900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS18900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS18970	COG2009	succinate dehydrogenase
HUT05_RS18980	COG1053	succinate dehydrogenase
HUT05_RS19025	COG1309	transcriptional regulator
HUT05_RS19030	COG2409	Drug exporters of the RND superfamily
HUT05_RS19035	COG0745	RESPONSE REGULATOR receiver
HUT05_RS19040	COG2205	protein histidine kinase activity
HUT05_RS19055	COG1408	metallophosphoesterase
HUT05_RS19070	COG1295	ribonuclease BN
HUT05_RS19080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT05_RS19105	COG0180	Tryptophanyl-tRNA synthetase
HUT05_RS19110	COG1595	DNA-templated transcription, initiation
HUT05_RS19130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT05_RS19135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT05_RS19145	COG0754	glutathionylspermidine amidase activity
HUT05_RS19160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT05_RS19165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT05_RS19170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT05_RS19185	COG4176	ABC-type proline glycine betaine transport system permease component
HUT05_RS19190	COG0517	IMP dehydrogenase activity
HUT05_RS19190	COG4175	Glycine betaine
HUT05_RS19200	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS19265	COG0039	L-malate dehydrogenase activity
HUT05_RS19285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT05_RS19300	COG0515	serine threonine protein kinase
HUT05_RS19300	COG2815	serine threonine protein kinase
HUT05_RS19310	COG2815	serine threonine protein kinase
HUT05_RS19310	COG0515	serine threonine protein kinase
HUT05_RS19340	COG0138	bifunctional purine biosynthesis protein purh
HUT05_RS19370	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT05_RS19385	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT05_RS19390	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HUT05_RS19395	COG0714	Associated with various cellular activities
HUT05_RS19410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS19410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT05_RS19450	COG2197	response regulator
HUT05_RS19495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT05_RS19495	COG0519	Catalyzes the synthesis of GMP from XMP
HUT05_RS19520	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS19525	COG0515	serine threonine protein kinase
HUT05_RS19530	COG0515	serine threonine protein kinase
HUT05_RS19535	COG0515	serine threonine protein kinase
HUT05_RS19535	COG2815	serine threonine protein kinase
HUT05_RS19540	COG0515	serine threonine protein kinase
HUT05_RS19545	COG0515	serine threonine protein kinase
HUT05_RS19545	COG2815	serine threonine protein kinase
HUT05_RS19550	COG0515	serine threonine protein kinase
HUT05_RS19550	COG2815	serine threonine protein kinase
HUT05_RS19560	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT05_RS19570	COG0516	GMP reductase activity
HUT05_RS19580	COG1595	DNA-templated transcription, initiation
HUT05_RS19595	COG0583	DNA-binding transcription factor activity
HUT05_RS19605	COG4221	oxidoreductase activity
HUT05_RS19615	COG0459	protein refolding
HUT05_RS19620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT05_RS19625	COG0726	polysaccharide deacetylase
HUT05_RS19630	COG0726	polysaccharide deacetylase
HUT05_RS19640	COG4941	Belongs to the sigma-70 factor family
HUT05_RS19650	COG1316	TRANSCRIPTIONal
HUT05_RS19655	COG1609	Transcriptional regulator
HUT05_RS19670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT05_RS19695	COG0802	atpase or kinase
HUT05_RS19705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT05_RS19715	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT05_RS19725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS19735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT05_RS19750	COG1072	(Pantothenic acid kinase))
HUT05_RS19760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT05_RS19765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT05_RS19770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT05_RS19805	COG2843	Capsule synthesis protein
HUT05_RS19815	COG0101	tRNA pseudouridine synthase activity
HUT05_RS19820	COG0203	ribosomal protein L17
HUT05_RS19825	COG0202	RNA polymerase activity
HUT05_RS19835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT05_RS19840	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUT05_RS19845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT05_RS19850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT05_RS19860	COG0201	protein transport
HUT05_RS19865	COG0563	adenylate kinase activity
HUT05_RS19880	COG0200	Binds to the 23S rRNA
HUT05_RS19885	COG1841	ribosomal large subunit assembly
HUT05_RS19890	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT05_RS19895	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT05_RS19900	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT05_RS19905	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT05_RS19910	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT05_RS19915	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT05_RS19920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT05_RS19925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT05_RS19930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT05_RS19935	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT05_RS19940	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT05_RS19945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT05_RS19950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT05_RS19955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT05_RS19960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT05_RS19965	COG0089	rRNA binding
HUT05_RS19970	COG0088	Forms part of the polypeptide exit tunnel
HUT05_RS19975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT05_RS19980	COG0051	transcription antitermination factor activity, RNA binding
HUT05_RS19995	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
HUT05_RS20000	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HUT05_RS20010	COG2133	pyrroloquinoline quinone binding
HUT05_RS20020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT05_RS20025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT05_RS20030	COG0049	tRNA binding
HUT05_RS20035	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUT05_RS20045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT05_RS20050	COG0085	RNA polymerase activity
HUT05_RS20055	COG0222	ribosome binding
HUT05_RS20060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUT05_RS20075	COG0081	regulation of translation
HUT05_RS20080	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT05_RS20090	COG0250	Participates in transcription elongation, termination and antitermination
HUT05_RS20105	COG0436	Aminotransferase
HUT05_RS20110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT05_RS20120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT05_RS20125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT05_RS20135	COG0477	Major facilitator Superfamily
HUT05_RS20150	COG2030	dehydratase
HUT05_RS20155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT05_RS20190	COG1666	GTP binding
HUT05_RS20195	COG2261	transglycosylase associated protein
HUT05_RS20210	COG3304	Inner membrane component domain
HUT05_RS20215	COG0501	Belongs to the peptidase M48B family
HUT05_RS20220	COG1007	ATP synthesis coupled electron transport
HUT05_RS20230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT05_RS20235	COG0713	ATP synthesis coupled electron transport
HUT05_RS20240	COG0839	Belongs to the complex I subunit 6 family
HUT05_RS20245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT05_RS20250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT05_RS20255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT05_RS20260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT05_RS20265	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT05_RS20275	COG4585	Histidine kinase
HUT05_RS20285	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT05_RS20285	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT05_RS20290	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT05_RS20305	COG1733	regulation of RNA biosynthetic process
HUT05_RS20310	COG0702	epimerase
HUT05_RS20325	COG4935	Belongs to the peptidase S8 family
HUT05_RS20325	COG2234	aminopeptidase activity
HUT05_RS20340	COG0154	amidase activity
HUT05_RS20355	COG1131	(ABC) transporter
HUT05_RS20380	COG0561	phosphatase activity
HUT05_RS20395	COG0514	ATP-dependent DNA helicase (RecQ)
HUT05_RS20400	COG1007	ATP synthesis coupled electron transport
HUT05_RS20410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT05_RS20415	COG0713	ATP synthesis coupled electron transport
HUT05_RS20420	COG0839	Belongs to the complex I subunit 6 family
HUT05_RS20425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT05_RS20430	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT05_RS20435	COG1034	ATP synthesis coupled electron transport
HUT05_RS20440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT05_RS20450	COG0649	NAD binding
HUT05_RS20455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT05_RS20460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT05_RS20475	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HUT05_RS20475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS20480	COG0242	peptide deformylase activity
HUT05_RS20500	COG2226	methyltransferase
HUT05_RS20530	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT05_RS20545	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT05_RS20575	COG4106	trans-aconitate 2-methyltransferase activity
HUT05_RS20580	COG1053	succinate dehydrogenase
HUT05_RS20590	COG4213	ABC transporter substrate-binding protein
HUT05_RS20605	COG0183	Belongs to the thiolase family
HUT05_RS20620	COG1309	transcriptional regulator
HUT05_RS20645	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT05_RS20655	COG0163	prenyltransferase activity
HUT05_RS20670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUT05_RS20705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUT05_RS20710	COG1333	cytochrome c biogenesis protein
HUT05_RS20715	COG0785	Cytochrome C biogenesis protein
HUT05_RS20720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT05_RS20730	COG0406	alpha-ribazole phosphatase activity
HUT05_RS20735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT05_RS20760	COG0583	DNA-binding transcription factor activity
HUT05_RS20780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT05_RS20795	COG2175	clavaminate synthase activity
HUT05_RS20835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS20845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS20865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS20880	COG0604	alcohol dehydrogenase
HUT05_RS20885	COG1733	regulation of RNA biosynthetic process
HUT05_RS20895	COG1742	UPF0060 membrane protein
HUT05_RS20915	COG1690	Belongs to the RtcB family
HUT05_RS20935	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HUT05_RS20940	COG0018	arginyl-trna synthetase
HUT05_RS20970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT05_RS20980	COG0113	porphobilinogen synthase activity
HUT05_RS20990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT05_RS20990	COG1648	precorrin-2 dehydrogenase activity
HUT05_RS20995	COG0181	hydroxymethylbilane synthase activity
HUT05_RS21000	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT05_RS21005	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUT05_RS21060	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUT05_RS21105	COG0842	Transport permease protein
HUT05_RS21105	COG1129	ABC transporter
HUT05_RS21120	COG4991	sh3 domain protein
HUT05_RS21125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT05_RS21125	COG0515	serine threonine protein kinase
HUT05_RS21130	COG0129	dihydroxy-acid dehydratase activity
HUT05_RS21140	COG1082	Xylose isomerase domain protein TIM barrel
HUT05_RS21145	COG0248	Ppx GppA phosphatase
HUT05_RS21165	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HUT05_RS21175	COG1194	a g-specific adenine glycosylase
HUT05_RS21180	COG1595	DNA-templated transcription, initiation
HUT05_RS21190	COG0745	RESPONSE REGULATOR receiver
HUT05_RS21195	COG2205	protein histidine kinase activity
HUT05_RS21210	COG0477	Major facilitator Superfamily
HUT05_RS21220	COG0739	heme binding
HUT05_RS21250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT05_RS21265	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT05_RS21275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT05_RS21280	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT05_RS21290	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HUT05_RS21305	COG1660	Displays ATPase and GTPase activities
HUT05_RS21310	COG2197	response regulator
HUT05_RS21325	COG0649	NAD binding
HUT05_RS21365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUT05_RS21380	COG0302	gtp cyclohydrolase
HUT05_RS21395	COG0037	tRNA processing
HUT05_RS21405	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT05_RS21410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT05_RS21420	COG0586	Pfam SNARE associated Golgi protein
HUT05_RS21425	COG0393	Putative heavy-metal-binding
HUT05_RS21430	COG0789	Transcriptional regulator
HUT05_RS21435	COG0076	glutamate decarboxylase activity
HUT05_RS21455	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS21490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT05_RS21500	COG0254	rRNA binding
HUT05_RS21505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT05_RS21510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT05_RS21515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT05_RS21540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT05_RS21540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT05_RS21585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT05_RS21590	COG1754	DNA topoisomerase type I activity
HUT05_RS21590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT05_RS21615	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT05_RS21620	COG2172	sigma factor antagonist activity
HUT05_RS21625	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT05_RS21630	COG1205	dead DEAH box helicase
HUT05_RS21630	COG1111	helicase
HUT05_RS21690	COG0659	secondary active sulfate transmembrane transporter activity
HUT05_RS21695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT05_RS21710	COG2267	carboxylic ester hydrolase activity
HUT05_RS21740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT05_RS21765	COG0003	Pfam Anion-transporting ATPase
HUT05_RS21775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT05_RS21785	COG1408	metallophosphoesterase
HUT05_RS21800	COG1609	Transcriptional regulator
HUT05_RS21855	COG1316	TRANSCRIPTIONal
HUT05_RS21875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT05_RS21880	COG0477	Major facilitator Superfamily
HUT05_RS21885	COG3387	PFAM Glycoside hydrolase 15-related
HUT05_RS21925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT05_RS21930	COG1595	DNA-templated transcription, initiation
HUT05_RS21935	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT05_RS21935	COG2319	Wd-40 repeat
HUT05_RS21960	COG0701	Predicted permease
HUT05_RS21985	COG1595	DNA-templated transcription, initiation
HUT05_RS22015	COG2205	protein histidine kinase activity
HUT05_RS22040	COG0384	phenazine biosynthesis protein PhzF
HUT05_RS22050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUT05_RS22055	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT05_RS22085	COG0693	protein deglycase activity
HUT05_RS22095	COG1802	Transcriptional regulator
HUT05_RS22145	COG2197	response regulator
HUT05_RS22150	COG4585	Histidine kinase
HUT05_RS22155	COG1136	(ABC) transporter
HUT05_RS22155	COG0577	efflux transmembrane transporter activity
HUT05_RS22165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT05_RS22180	COG1131	(ABC) transporter
HUT05_RS22185	COG3559	Exporter of polyketide antibiotics
HUT05_RS22195	COG2124	cytochrome p450
HUT05_RS22205	COG2197	response regulator
HUT05_RS22210	COG4585	Histidine kinase
HUT05_RS22215	COG2197	response regulator
HUT05_RS22220	COG4585	Histidine kinase
HUT05_RS22245	COG3460	Phenylacetate-CoA oxygenase
HUT05_RS22250	COG3396	Phenylacetate-CoA oxygenase
HUT05_RS22270	COG3844	kynureninase activity
HUT05_RS22275	COG3483	tryptophan 2,3-dioxygenase activity
HUT05_RS22285	COG0477	Major facilitator Superfamily
HUT05_RS22290	COG0191	fructose-bisphosphate aldolase activity
HUT05_RS22295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUT05_RS22310	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT05_RS22340	COG0542	response to heat
HUT05_RS22370	COG4213	ABC transporter substrate-binding protein
HUT05_RS22385	COG0789	Transcriptional regulator
HUT05_RS22390	COG0484	heat shock protein binding
HUT05_RS22395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT05_RS22400	COG0443	Heat shock 70 kDa protein
HUT05_RS22405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT05_RS22410	COG2181	nitrate reductase activity
HUT05_RS22410	COG0247	lactate metabolic process
HUT05_RS22425	COG2814	Major facilitator Superfamily
HUT05_RS22440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT05_RS22600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT05_RS22610	COG3645	SOS response
HUT05_RS22630	COG0717	Belongs to the dCTP deaminase family
HUT05_RS22680	COG2188	Transcriptional regulator
HUT05_RS22690	COG2188	Transcriptional regulator
HUT05_RS22720	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HUT05_RS22725	COG0732	type I restriction modification DNA specificity domain
HUT05_RS22730	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUT05_RS22755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT05_RS22760	COG0640	Transcriptional regulator
HUT05_RS22765	COG2226	methyltransferase
HUT05_RS22775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS22785	COG0515	serine threonine protein kinase
HUT05_RS22785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT05_RS22790	COG1846	Transcriptional regulator
HUT05_RS22795	COG1902	pentaerythritol trinitrate reductase activity
HUT05_RS22805	COG2205	protein histidine kinase activity
HUT05_RS22810	COG0745	RESPONSE REGULATOR receiver
HUT05_RS22825	COG1376	ErfK ybiS ycfS ynhG family protein
HUT05_RS22880	COG1846	Transcriptional regulator
HUT05_RS22890	COG4977	sequence-specific DNA binding
HUT05_RS22920	COG0531	amino acid
HUT05_RS22925	COG4977	sequence-specific DNA binding
HUT05_RS22950	COG0475	glutathione-regulated potassium exporter activity
HUT05_RS22965	COG1834	amidinotransferase
HUT05_RS22970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT05_RS22975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT05_RS22975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT05_RS22990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT05_RS23000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT05_RS23045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT05_RS23050	COG2814	Major facilitator Superfamily
HUT05_RS23060	COG0248	Ppx GppA phosphatase
HUT05_RS23090	COG1764	response to oxidative stress
HUT05_RS23095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT05_RS23160	COG0477	Major facilitator Superfamily
HUT05_RS23170	COG4585	Histidine kinase
HUT05_RS23175	COG2409	Drug exporters of the RND superfamily
HUT05_RS23185	COG0714	Associated with various cellular activities
HUT05_RS23210	COG3764	Sortase (surface protein transpeptidase)
HUT05_RS23260	COG1073	alpha beta
HUT05_RS23260	COG2226	methyltransferase
HUT05_RS23315	COG0366	Alpha amylase catalytic
HUT05_RS23330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT05_RS23350	COG0701	Predicted permease
HUT05_RS23365	COG0222	ribosome binding
HUT05_RS23400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT05_RS23405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT05_RS23415	COG1289	transmembrane transporter activity
HUT05_RS23425	COG0583	DNA-binding transcription factor activity
HUT05_RS23440	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT05_RS23445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT05_RS23470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT05_RS23485	COG1741	Belongs to the pirin family
HUT05_RS23490	COG0477	Major facilitator Superfamily
HUT05_RS23510	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS23515	COG1362	aminopeptidase activity
HUT05_RS23565	COG2814	Major facilitator Superfamily
HUT05_RS23580	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT05_RS23585	COG0022	dehydrogenase e1 component
HUT05_RS23600	COG0515	serine threonine protein kinase
HUT05_RS23605	COG0515	serine threonine protein kinase
HUT05_RS23620	COG0604	alcohol dehydrogenase
HUT05_RS23620	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS23620	COG3321	synthase
HUT05_RS23640	COG0303	'Molybdopterin
HUT05_RS23670	COG1309	transcriptional regulator
HUT05_RS23675	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT05_RS23700	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS23720	COG1733	regulation of RNA biosynthetic process
HUT05_RS23725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT05_RS23740	COG1716	ATPase activity
HUT05_RS23745	COG1716	ATPase activity
HUT05_RS23760	COG0768	penicillin binding
HUT05_RS23765	COG0515	serine threonine protein kinase
HUT05_RS23770	COG3764	Sortase (surface protein transpeptidase)
HUT05_RS23775	COG3764	Sortase (surface protein transpeptidase)
HUT05_RS23790	COG3764	Sortase (surface protein transpeptidase)
HUT05_RS23805	COG0705	Rhomboid family
HUT05_RS23830	COG0515	serine threonine protein kinase
HUT05_RS23850	COG1116	anion transmembrane transporter activity
HUT05_RS23860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUT05_RS23865	COG2188	Transcriptional regulator
HUT05_RS23925	COG0582	viral genome integration into host DNA
HUT05_RS23940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT05_RS23945	COG0187	DNA topoisomerase II activity
HUT05_RS23950	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT05_RS23955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT05_RS23960	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT05_RS23965	COG0592	DNA-directed DNA polymerase activity
HUT05_RS23970	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUT05_RS23980	COG0594	ribonuclease P activity
HUT05_RS23985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUT05_RS23990	COG0706	membrane insertase activity
HUT05_RS24000	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT05_RS24005	COG1192	Involved in chromosome partitioning
HUT05_RS24020	COG3118	belongs to the thioredoxin family
HUT05_RS24025	COG0492	ferredoxin-NADP+ reductase activity
HUT05_RS24035	COG1595	DNA-templated transcription, initiation
HUT05_RS24040	COG0515	serine threonine protein kinase
HUT05_RS24040	COG2815	serine threonine protein kinase
HUT05_RS24055	COG0617	tRNA 3'-terminal CCA addition
HUT05_RS24070	COG1260	myo-inositol-1-phosphate synthase
HUT05_RS24080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUT05_RS24110	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT05_RS24115	COG0629	single-stranded DNA binding
HUT05_RS24120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT05_RS24125	COG0359	binds to the 23S rRNA
HUT05_RS24135	COG0305	Participates in initiation and elongation during chromosome replication
HUT05_RS24155	COG2814	Major facilitator Superfamily
HUT05_RS24190	COG0626	cystathionine gamma-synthase activity
HUT05_RS24195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT05_RS24200	COG1950	PFAM Membrane protein of
HUT05_RS24205	COG0662	Cupin 2, conserved barrel domain protein
HUT05_RS24230	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT05_RS24245	COG1609	Transcriptional regulator
HUT05_RS24250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT05_RS24260	COG1271	oxidase subunit
HUT05_RS24265	COG1294	oxidase, subunit
HUT05_RS24270	COG4988	ABC transporter
HUT05_RS24280	COG0561	phosphatase activity
HUT05_RS24295	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUT05_RS24300	COG0789	Transcriptional regulator
HUT05_RS24315	COG1131	(ABC) transporter
HUT05_RS24345	COG0561	phosphatase activity
HUT05_RS24350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT05_RS24360	COG2837	iron assimilation
HUT05_RS24375	COG1999	signal sequence binding
HUT05_RS24400	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HUT05_RS24405	COG0006	proline dipeptidase activity
HUT05_RS24425	COG0653	protein targeting
HUT05_RS24445	COG0515	serine threonine protein kinase
HUT05_RS24445	COG2815	serine threonine protein kinase
HUT05_RS24450	COG1278	Cold shock
HUT05_RS24490	COG1595	DNA-templated transcription, initiation
HUT05_RS24495	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS24500	COG0784	Response regulator, receiver
HUT05_RS24530	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUT05_RS24570	COG1733	regulation of RNA biosynthetic process
HUT05_RS24575	COG1846	Transcriptional regulator
HUT05_RS24590	COG0745	RESPONSE REGULATOR receiver
HUT05_RS24595	COG2205	protein histidine kinase activity
HUT05_RS24605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT05_RS24610	COG0477	Major facilitator Superfamily
HUT05_RS24620	COG3467	pyridoxamine 5'-phosphate
HUT05_RS24625	COG2353	YceI-like domain
HUT05_RS24650	COG1191	sigma factor activity
HUT05_RS24655	COG1191	sigma factor activity
HUT05_RS24835	COG0305	Participates in initiation and elongation during chromosome replication
HUT05_RS25005	COG0159	tryptophan synthase activity
HUT05_RS25055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT05_RS25245	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS25250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT05_RS25275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT05_RS25290	COG1196	nuclear chromosome segregation
HUT05_RS25290	COG0741	lytic transglycosylase activity
HUT05_RS25290	COG0739	heme binding
HUT05_RS25445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUT05_RS25460	COG0433	COG0433 Predicted ATPase
HUT05_RS25500	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS25515	COG1653	transport
HUT05_RS25525	COG0395	ABC-type sugar transport system, permease component
HUT05_RS25530	COG3345	alpha-galactosidase
HUT05_RS25570	COG0477	Major facilitator Superfamily
HUT05_RS25590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUT05_RS25610	COG0151	Belongs to the GarS family
HUT05_RS25625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT05_RS25635	COG2197	response regulator
HUT05_RS25670	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT05_RS25675	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT05_RS25680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT05_RS25710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT05_RS25740	COG1643	Atp-dependent helicase
HUT05_RS25800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT05_RS25805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT05_RS25810	COG1846	Transcriptional regulator
HUT05_RS25815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT05_RS25815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT05_RS25840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUT05_RS25845	COG0579	oxidoreductase
HUT05_RS25875	COG1252	NADH dehydrogenase
HUT05_RS25935	COG1846	Transcriptional regulator
HUT05_RS25950	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS25960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT05_RS25975	COG1196	nuclear chromosome segregation
HUT05_RS25975	COG0741	lytic transglycosylase activity
HUT05_RS25975	COG0739	heme binding
HUT05_RS25980	COG0671	phosphoesterase, PA-phosphatase related
HUT05_RS25985	COG0277	FAD linked oxidase domain protein
HUT05_RS25990	COG0306	phosphate transporter
HUT05_RS26000	COG1937	Protein conserved in bacteria
HUT05_RS26015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT05_RS26020	COG0581	inorganic phosphate transmembrane transporter activity
HUT05_RS26045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUT05_RS26065	COG1725	Transcriptional regulator
HUT05_RS26070	COG0456	acetyltransferase
HUT05_RS26075	COG0737	Belongs to the 5'-nucleotidase family
HUT05_RS26085	COG1132	(ABC) transporter
HUT05_RS26125	COG0745	RESPONSE REGULATOR receiver
HUT05_RS26140	COG1609	Transcriptional regulator
HUT05_RS26145	COG0745	RESPONSE REGULATOR receiver
HUT05_RS26170	COG2897	thiosulfate sulfurtransferase activity
HUT05_RS26205	COG3485	protocatechuate 3,4-dioxygenase
HUT05_RS26215	COG0354	folic acid binding
HUT05_RS26220	COG1490	D-aminoacyl-tRNA deacylase activity
HUT05_RS26230	COG4552	Acetyltransferase involved in intracellular survival and related
HUT05_RS26240	COG2186	Transcriptional regulator
HUT05_RS26250	COG2188	Transcriptional regulator
HUT05_RS26270	COG0546	phosphoglycolate phosphatase activity
HUT05_RS26290	COG3973	AAA domain
HUT05_RS26310	COG1733	regulation of RNA biosynthetic process
HUT05_RS26315	COG1090	epimerase
HUT05_RS26320	COG2267	carboxylic ester hydrolase activity
HUT05_RS26360	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS26395	COG0588	phosphoglycerate mutase activity
HUT05_RS26420	COG5002	protein histidine kinase activity
HUT05_RS26435	COG1329	Transcriptional regulator
HUT05_RS26440	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT05_RS26445	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT05_RS26450	COG0215	cysteine-tRNA ligase activity
HUT05_RS26455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT05_RS26550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT05_RS26630	COG3842	ATPase activity
HUT05_RS26690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT05_RS26695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT05_RS26715	COG3903	Transcriptional regulator
HUT05_RS26715	COG3629	intracellular signal transduction
HUT05_RS26805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUT05_RS26825	COG3300	MHYT domain
HUT05_RS26825	COG5001	Diguanylate cyclase
HUT05_RS26835	COG1105	Belongs to the carbohydrate kinase PfkB family
HUT05_RS26840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUT05_RS26865	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUT05_RS26870	COG0463	Glycosyl transferase, family 2
HUT05_RS26890	COG0459	protein refolding
HUT05_RS26915	COG2318	DinB family
HUT05_RS26935	COG0667	Aldo Keto reductase
HUT05_RS26940	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUT05_RS26945	COG1737	Transcriptional regulator
HUT05_RS26995	COG3973	AAA domain
HUT05_RS27005	COG1061	Type III restriction enzyme res subunit
HUT05_RS27025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT05_RS27045	COG1278	Cold shock
HUT05_RS27050	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT05_RS27055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUT05_RS27065	COG2814	Major facilitator Superfamily
HUT05_RS27105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT05_RS27115	COG2252	PERMEase
HUT05_RS27145	COG0667	Aldo Keto reductase
HUT05_RS27190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT05_RS27195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUT05_RS27200	COG0277	FAD linked oxidase domain protein
HUT05_RS27200	COG0247	lactate metabolic process
HUT05_RS27210	COG5006	permease, DMT superfamily
HUT05_RS27230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT05_RS27245	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS27250	COG1024	Enoyl-CoA hydratase
HUT05_RS27260	COG0515	serine threonine protein kinase
HUT05_RS27260	COG2815	serine threonine protein kinase
HUT05_RS27270	COG0259	pyridoxamine-phosphate oxidase activity
HUT05_RS27280	COG0583	DNA-binding transcription factor activity
HUT05_RS27300	COG4821	SIS domain
HUT05_RS27310	COG0596	Alpha beta hydrolase
HUT05_RS27310	COG2945	thiolester hydrolase activity
HUT05_RS27320	COG1131	(ABC) transporter
HUT05_RS27360	COG1595	DNA-templated transcription, initiation
HUT05_RS27375	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS27380	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS27385	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS27400	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS27405	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS27435	COG1024	Enoyl-CoA hydratase
HUT05_RS27445	COG1231	oxidoreductase activity
HUT05_RS27450	COG2072	flavoprotein involved in K transport
HUT05_RS27455	COG1595	DNA-templated transcription, initiation
HUT05_RS27505	COG0259	pyridoxamine-phosphate oxidase activity
HUT05_RS27520	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS27550	COG1280	lysine exporter protein (LysE YggA)
HUT05_RS27555	COG1522	sequence-specific DNA binding
HUT05_RS27560	COG1309	transcriptional regulator
HUT05_RS27570	COG0515	serine threonine protein kinase
HUT05_RS27570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT05_RS27580	COG1024	Enoyl-CoA hydratase
HUT05_RS27595	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS27610	COG3629	intracellular signal transduction
HUT05_RS27610	COG3903	Transcriptional regulator
HUT05_RS27650	COG2267	carboxylic ester hydrolase activity
HUT05_RS27675	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT05_RS27730	COG1686	Belongs to the peptidase S11 family
HUT05_RS27755	COG0386	Belongs to the glutathione peroxidase family
HUT05_RS27770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT05_RS27815	COG2197	response regulator
HUT05_RS27820	COG3903	Transcriptional regulator
HUT05_RS27820	COG3629	intracellular signal transduction
HUT05_RS27825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT05_RS27840	COG0667	Aldo Keto reductase
HUT05_RS27925	COG1846	Transcriptional regulator
HUT05_RS27935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT05_RS27945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT05_RS27955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT05_RS27960	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS27985	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT05_RS27995	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS28000	COG4689	acetoacetate decarboxylase
HUT05_RS28005	COG1414	Transcriptional regulator
HUT05_RS28025	COG1846	Transcriptional regulator
HUT05_RS28030	COG3384	dioxygenase
HUT05_RS28035	COG1247	-acetyltransferase
HUT05_RS28055	COG0477	Major facilitator Superfamily
HUT05_RS28060	COG1349	DNA-binding transcription factor activity
HUT05_RS28070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT05_RS28070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT05_RS28070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT05_RS28090	COG3191	aminopeptidase activity
HUT05_RS28105	COG1970	mechanosensitive ion channel activity
HUT05_RS28115	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUT05_RS28125	COG0477	Major facilitator Superfamily
HUT05_RS28140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT05_RS28145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT05_RS28155	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT05_RS28160	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT05_RS28160	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT05_RS28165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT05_RS28185	COG0454	-acetyltransferase
HUT05_RS28190	COG0708	Exodeoxyribonuclease III
HUT05_RS28210	COG2267	carboxylic ester hydrolase activity
HUT05_RS28215	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS28225	COG4946	Tricorn protease homolog
HUT05_RS28225	COG0793	Belongs to the peptidase S41A family
HUT05_RS28235	COG2409	Drug exporters of the RND superfamily
HUT05_RS28240	COG0442	prolyl-tRNA aminoacylation
HUT05_RS28265	COG1073	alpha beta
HUT05_RS28265	COG2226	methyltransferase
HUT05_RS28285	COG1764	response to oxidative stress
HUT05_RS28290	COG1846	Transcriptional regulator
HUT05_RS28295	COG1122	ATPase activity
HUT05_RS28305	COG0310	cobalt ion transport
HUT05_RS28320	COG0768	penicillin binding
HUT05_RS28415	COG1660	Displays ATPase and GTPase activities
HUT05_RS28420	COG0789	Transcriptional regulator
HUT05_RS28475	COG0084	hydrolase, TatD family'
HUT05_RS28480	COG3583	domain protein
HUT05_RS28480	COG3584	3D domain protein
HUT05_RS28485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT05_RS28490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT05_RS28500	COG0488	(ABC) transporter
HUT05_RS28540	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUT05_RS28555	COG2197	response regulator
HUT05_RS28565	COG4106	trans-aconitate 2-methyltransferase activity
HUT05_RS28580	COG1309	transcriptional regulator
HUT05_RS28590	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUT05_RS28605	COG0193	aminoacyl-tRNA hydrolase activity
HUT05_RS28610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUT05_RS28615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT05_RS28620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT05_RS28630	COG4585	Histidine kinase
HUT05_RS28660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT05_RS28700	COG0477	Major facilitator Superfamily
HUT05_RS28705	COG1136	(ABC) transporter
HUT05_RS28710	COG1136	(ABC) transporter
HUT05_RS28710	COG0577	efflux transmembrane transporter activity
HUT05_RS28775	COG2124	cytochrome p450
HUT05_RS28790	COG0148	phosphopyruvate hydratase activity
HUT05_RS28815	COG1252	NADH dehydrogenase
HUT05_RS28820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT05_RS28825	COG1136	(ABC) transporter
HUT05_RS28825	COG0577	efflux transmembrane transporter activity
HUT05_RS28830	COG1136	(ABC) transporter
HUT05_RS28865	COG0183	Belongs to the thiolase family
HUT05_RS28870	COG2755	lipolytic protein G-D-S-L family
HUT05_RS28885	COG4221	oxidoreductase activity
HUT05_RS28905	COG1174	glycine betaine transport
HUT05_RS28915	COG2986	histidine ammonia-lyase
HUT05_RS28955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT05_RS28960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS28970	COG1228	amidohydrolase
HUT05_RS28980	COG1191	sigma factor activity
HUT05_RS28985	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT05_RS29015	COG3104	oligopeptide transport
HUT05_RS29020	COG0745	RESPONSE REGULATOR receiver
HUT05_RS29025	COG2205	protein histidine kinase activity
HUT05_RS29040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUT05_RS29050	COG1902	pentaerythritol trinitrate reductase activity
HUT05_RS29055	COG0789	Transcriptional regulator
HUT05_RS29075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT05_RS29100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT05_RS29105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT05_RS29155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS29165	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS29170	COG0596	Alpha beta hydrolase
HUT05_RS29185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT05_RS29200	COG1802	Transcriptional regulator
HUT05_RS29300	COG1129	ABC transporter
HUT05_RS29305	COG0154	amidase activity
HUT05_RS29325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT05_RS29330	COG0436	Aminotransferase
HUT05_RS29365	COG1316	TRANSCRIPTIONal
HUT05_RS29375	COG1316	TRANSCRIPTIONal
HUT05_RS29385	COG1316	TRANSCRIPTIONal
HUT05_RS29390	COG1316	TRANSCRIPTIONal
HUT05_RS29395	COG1316	TRANSCRIPTIONal
HUT05_RS29420	COG0778	Nitroreductase
HUT05_RS29420	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT05_RS29425	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT05_RS29460	COG1620	l-lactate permease
HUT05_RS29465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT05_RS29470	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT05_RS29480	COG1482	cell wall glycoprotein biosynthetic process
HUT05_RS29495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT05_RS29495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT05_RS29495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT05_RS29530	COG0714	Associated with various cellular activities
HUT05_RS29550	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT05_RS29555	COG0745	RESPONSE REGULATOR receiver
HUT05_RS29560	COG5002	protein histidine kinase activity
HUT05_RS29565	COG0823	Involved in the tonB-independent uptake of proteins
HUT05_RS29570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT05_RS29575	COG2197	response regulator
HUT05_RS29580	COG3214	Protein conserved in bacteria
HUT05_RS29590	COG0653	protein targeting
HUT05_RS29615	COG2902	Dehydrogenase
HUT05_RS29620	COG1134	teichoic acid transport
HUT05_RS29635	COG2197	response regulator
HUT05_RS29650	COG1846	Transcriptional regulator
HUT05_RS29655	COG1764	response to oxidative stress
HUT05_RS29665	COG1216	Glycosyl transferase, family 2
HUT05_RS29670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT05_RS29675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT05_RS29675	COG0463	Glycosyl transferase, family 2
HUT05_RS29680	COG0395	ABC-type sugar transport system, permease component
HUT05_RS29700	COG0515	serine threonine protein kinase
HUT05_RS29705	COG0515	serine threonine protein kinase
HUT05_RS29710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT05_RS29725	COG2884	Cell division ATP-binding protein ftsE
HUT05_RS29735	COG0793	Belongs to the peptidase S41A family
HUT05_RS29740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT05_RS29770	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT05_RS29775	COG2124	cytochrome p450
HUT05_RS29785	COG0583	DNA-binding transcription factor activity
HUT05_RS29815	COG2223	nitrite transmembrane transporter activity
HUT05_RS29845	COG3973	AAA domain
HUT05_RS29855	COG0776	regulation of translation
HUT05_RS29860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT05_RS29865	COG1678	Uncharacterized ACR, COG1678
HUT05_RS29880	COG1175	transmembrane transport
HUT05_RS29885	COG0395	ABC-type sugar transport system, permease component
HUT05_RS29890	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT05_RS29940	COG3654	unkown
HUT05_RS29960	COG4948	Mandelate Racemase Muconate Lactonizing
HUT05_RS29985	COG1174	glycine betaine transport
HUT05_RS29995	COG1174	glycine betaine transport
HUT05_RS30005	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT05_RS30020	COG0277	FAD linked oxidase domain protein
HUT05_RS30055	COG1335	isochorismatase
HUT05_RS30065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUT05_RS30075	COG1113	amino acid transport
HUT05_RS30100	COG1234	tRNA 3'-trailer cleavage
HUT05_RS30105	COG1263	PTS System
HUT05_RS30110	COG1263	PTS System
HUT05_RS30115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT05_RS30120	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT05_RS30130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUT05_RS30170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT05_RS30185	COG4555	ABC transporter
HUT05_RS30200	COG2733	membrane
HUT05_RS30245	COG3629	intracellular signal transduction
HUT05_RS30245	COG3903	Transcriptional regulator
HUT05_RS30260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT05_RS30365	COG3764	Sortase (surface protein transpeptidase)
HUT05_RS30370	COG0477	Major facilitator Superfamily
HUT05_RS30385	COG0706	membrane insertase activity
HUT05_RS30395	COG4702	Belongs to the UPF0303 family
HUT05_RS30400	COG0673	inositol 2-dehydrogenase activity
HUT05_RS30405	COG1940	carbohydrate kinase activity
HUT05_RS30415	COG2188	Transcriptional regulator
HUT05_RS30420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT05_RS30510	COG3397	chitin binding
HUT05_RS30520	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS30535	COG1126	abc transporter atp-binding protein
HUT05_RS30540	COG0765	amino acid transport
HUT05_RS30545	COG0765	amino acid transport
HUT05_RS30550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT05_RS30565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT05_RS30580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS30630	COG0406	alpha-ribazole phosphatase activity
HUT05_RS30645	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT05_RS30655	COG0745	RESPONSE REGULATOR receiver
HUT05_RS30685	COG1175	transmembrane transport
HUT05_RS30710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUT05_RS30715	COG4977	sequence-specific DNA binding
HUT05_RS30725	COG0589	response to stress
HUT05_RS30735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT05_RS30770	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT05_RS30795	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS30810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT05_RS30815	COG1309	transcriptional regulator
HUT05_RS30820	COG0586	Pfam SNARE associated Golgi protein
HUT05_RS30830	COG1946	Acyl-CoA thioesterase
HUT05_RS30835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT05_RS30850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT05_RS30860	COG0028	Belongs to the TPP enzyme family
HUT05_RS30870	COG2356	endonuclease I
HUT05_RS30875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT05_RS30910	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT05_RS30915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT05_RS30945	COG0456	acetyltransferase
HUT05_RS30945	COG1846	Transcriptional regulator
HUT05_RS30960	COG0673	inositol 2-dehydrogenase activity
HUT05_RS30975	COG1869	D-ribose catabolic process
HUT05_RS30980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS30985	COG1879	ABC-type sugar transport system periplasmic component
HUT05_RS30990	COG1129	ABC transporter
HUT05_RS31015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT05_RS31040	COG2409	Drug exporters of the RND superfamily
HUT05_RS31050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT05_RS31060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS31075	COG3962	Belongs to the TPP enzyme family
HUT05_RS31135	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS31145	COG0728	peptidoglycan biosynthetic process
HUT05_RS31160	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS31220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT05_RS31255	COG4770	biotin carboxylase activity
HUT05_RS31260	COG4770	biotin carboxylase activity
HUT05_RS31275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT05_RS31325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT05_RS31330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS31350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT05_RS31370	COG2091	lysine biosynthetic process via aminoadipic acid
HUT05_RS31375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT05_RS31395	COG0477	Major facilitator Superfamily
HUT05_RS31400	COG0656	L-ascorbic acid biosynthetic process
HUT05_RS31405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT05_RS31455	COG0629	single-stranded DNA binding
HUT05_RS31580	COG2346	COG2346, Truncated hemoglobins
HUT05_RS31585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT05_RS31630	COG1486	melibiose metabolic process
HUT05_RS31635	COG0395	ABC-type sugar transport system, permease component
HUT05_RS31640	COG1175	transmembrane transport
HUT05_RS31650	COG1940	carbohydrate kinase activity
HUT05_RS31660	COG0668	transmembrane transport
HUT05_RS31675	COG1136	(ABC) transporter
HUT05_RS31705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS31765	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT05_RS31775	COG0584	glycerophosphoryl diester phosphodiesterase
HUT05_RS31795	COG1349	DNA-binding transcription factor activity
HUT05_RS31805	COG0395	ABC-type sugar transport system, permease component
HUT05_RS31810	COG1175	transmembrane transport
HUT05_RS31815	COG1653	transport
HUT05_RS31820	COG1070	Carbohydrate kinase
HUT05_RS31825	COG0588	phosphoglycerate mutase activity
HUT05_RS31840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUT05_RS31845	COG1113	amino acid transport
HUT05_RS31855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS31860	COG1116	anion transmembrane transporter activity
HUT05_RS31865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT05_RS31880	COG1268	BioY protein
HUT05_RS31890	COG0515	serine threonine protein kinase
HUT05_RS31895	COG1113	amino acid transport
HUT05_RS31900	COG0698	ribose 5-phosphate isomerase
HUT05_RS31910	COG4552	Acetyltransferase involved in intracellular survival and related
HUT05_RS31925	COG3594	Acyltransferase
HUT05_RS31935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT05_RS31935	COG0515	serine threonine protein kinase
HUT05_RS31940	COG0509	glycine decarboxylation via glycine cleavage system
HUT05_RS31955	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT05_RS31960	COG0740	serine-type endopeptidase activity
HUT05_RS31965	COG0740	serine-type endopeptidase activity
HUT05_RS31970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT05_RS31980	COG0525	valine-tRNA ligase activity
HUT05_RS31985	COG0285	dihydrofolate synthase activity
HUT05_RS31995	COG0105	UTP biosynthetic process
HUT05_RS32000	COG1077	Cell shape determining protein MreB Mrl
HUT05_RS32020	COG0772	Belongs to the SEDS family
HUT05_RS32045	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT05_RS32110	COG0076	glutamate decarboxylase activity
HUT05_RS32115	COG1252	NADH dehydrogenase
HUT05_RS32120	COG1595	DNA-templated transcription, initiation
HUT05_RS32130	COG0477	Major facilitator Superfamily
HUT05_RS32150	COG2326	polyphosphate kinase activity
HUT05_RS32155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT05_RS32180	COG1530	ribonuclease E activity
HUT05_RS32185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT05_RS32190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT05_RS32195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT05_RS32210	COG3540	Alkaline phosphatase
HUT05_RS32230	COG1215	transferase activity, transferring glycosyl groups
HUT05_RS32240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUT05_RS32250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT05_RS32265	COG0501	Belongs to the peptidase M48B family
HUT05_RS32280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT05_RS32290	COG0799	negative regulation of ribosome biogenesis
HUT05_RS32295	COG0588	phosphoglycerate mutase activity
HUT05_RS32320	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT05_RS32330	COG0495	leucyl-tRNA aminoacylation
HUT05_RS32340	COG1307	EDD domain protein, DegV family
HUT05_RS32345	COG1555	photosystem II stabilization
HUT05_RS32345	COG1596	polysaccharide export
HUT05_RS32350	COG1234	tRNA 3'-trailer cleavage
HUT05_RS32360	COG2353	YceI-like domain
HUT05_RS32380	COG0268	Binds directly to 16S ribosomal RNA
HUT05_RS32385	COG0481	GTPase activity
HUT05_RS32425	COG1420	regulation of RNA biosynthetic process
HUT05_RS32430	COG0484	heat shock protein binding
HUT05_RS32455	COG0793	Belongs to the peptidase S41A family
HUT05_RS32455	COG4946	Tricorn protease homolog
HUT05_RS32460	COG0537	adenosine 5'-monophosphoramidase activity
HUT05_RS32465	COG1234	tRNA 3'-trailer cleavage
HUT05_RS32470	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT05_RS32485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT05_RS32490	COG4948	Mandelate Racemase Muconate Lactonizing
HUT05_RS32495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS32520	COG2315	Protein conserved in bacteria
HUT05_RS32530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT05_RS32540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT05_RS32575	COG2723	6-phospho-beta-galactosidase activity
HUT05_RS32590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT05_RS32600	COG2409	Drug exporters of the RND superfamily
HUT05_RS32605	COG4585	Histidine kinase
HUT05_RS32610	COG2197	response regulator
HUT05_RS32620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT05_RS32625	COG4608	Belongs to the ABC transporter superfamily
HUT05_RS32630	COG0444	Belongs to the ABC transporter superfamily
HUT05_RS32640	COG0747	negative chemotaxis
HUT05_RS32645	COG2186	Transcriptional regulator
HUT05_RS32655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT05_RS32690	COG0456	acetyltransferase
HUT05_RS32750	COG1381	Involved in DNA repair and RecF pathway recombination
HUT05_RS32755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT05_RS32770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT05_RS32775	COG1121	(ABC) transporter
HUT05_RS32780	COG3443	Belongs to the bacterial solute-binding protein 9 family
HUT05_RS32780	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUT05_RS32785	COG0423	glycine-tRNA ligase activity
HUT05_RS32800	COG0116	Belongs to the methyltransferase superfamily
HUT05_RS32800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUT05_RS32820	COG0667	Aldo Keto reductase
HUT05_RS32830	COG0456	acetyltransferase
HUT05_RS32840	COG0477	Major facilitator Superfamily
HUT05_RS32875	COG1940	carbohydrate kinase activity
HUT05_RS32875	COG1846	Transcriptional regulator
HUT05_RS32880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT05_RS32880	COG0574	Belongs to the PEP-utilizing enzyme family
HUT05_RS32895	COG0546	phosphoglycolate phosphatase activity
HUT05_RS32940	COG0642	Histidine kinase
HUT05_RS32945	COG0745	RESPONSE REGULATOR receiver
HUT05_RS32955	COG0659	secondary active sulfate transmembrane transporter activity
HUT05_RS32965	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS32970	COG1309	transcriptional regulator
HUT05_RS32980	COG2146	nitrite reductase [NAD(P)H] activity
HUT05_RS32980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT05_RS32985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT05_RS33000	COG2197	response regulator
HUT05_RS33015	COG1733	regulation of RNA biosynthetic process
HUT05_RS33045	COG0243	molybdopterin cofactor binding
HUT05_RS33050	COG2949	membrane
HUT05_RS33060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT05_RS33070	COG0358	DNA primase activity
HUT05_RS33075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT05_RS33090	COG1070	Carbohydrate kinase
HUT05_RS33115	COG3263	regulation of cellular component size
HUT05_RS33125	COG3387	PFAM Glycoside hydrolase 15-related
HUT05_RS33140	COG1294	oxidase, subunit
HUT05_RS33150	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS33165	COG0589	response to stress
HUT05_RS33185	COG3290	protein histidine kinase activity
HUT05_RS33190	COG4565	transcriptional regulatory protein
HUT05_RS33220	COG1077	Cell shape determining protein MreB Mrl
HUT05_RS33225	COG0515	serine threonine protein kinase
HUT05_RS33225	COG2815	serine threonine protein kinase
HUT05_RS33240	COG0825	malonyl-CoA metabolic process
HUT05_RS33240	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUT05_RS33245	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS33255	COG2186	Transcriptional regulator
HUT05_RS33285	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT05_RS33285	COG1663	tetraacyldisaccharide 4'-kinase activity
HUT05_RS33305	COG4981	capsule polysaccharide biosynthetic process
HUT05_RS33355	COG1414	Transcriptional regulator
HUT05_RS33360	COG3386	PFAM SMP-30 Gluconolaconase
HUT05_RS33405	COG1175	transmembrane transport
HUT05_RS33410	COG0395	ABC-type sugar transport system, permease component
HUT05_RS33420	COG0730	response to heat
HUT05_RS33450	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT05_RS33460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT05_RS33470	COG4214	carbohydrate transport
HUT05_RS33505	COG1597	lipid kinase activity
HUT05_RS33515	COG2130	NADP-dependent
HUT05_RS33520	COG1764	response to oxidative stress
HUT05_RS33550	COG0583	DNA-binding transcription factor activity
HUT05_RS33560	COG1309	transcriptional regulator
HUT05_RS33585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT05_RS33590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT05_RS33595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT05_RS33615	COG2409	Drug exporters of the RND superfamily
HUT05_RS33630	COG0789	Transcriptional regulator
HUT05_RS33635	COG0667	Aldo Keto reductase
HUT05_RS33650	COG1309	transcriptional regulator
HUT05_RS33655	COG0477	Major facilitator Superfamily
HUT05_RS33670	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT05_RS33715	COG1358	cellular component organization or biogenesis
HUT05_RS33730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT05_RS33775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUT05_RS33860	COG1657	PFAM Prenyltransferase squalene oxidase
HUT05_RS33875	COG3845	ABC transporter
HUT05_RS33890	COG2124	cytochrome p450
HUT05_RS33895	COG0183	Belongs to the thiolase family
HUT05_RS33915	COG3033	Beta-eliminating lyase
HUT05_RS33965	COG4122	O-methyltransferase activity
HUT05_RS34010	COG1309	transcriptional regulator
HUT05_RS34015	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS34050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS34060	COG2247	cell wall binding repeat
HUT05_RS34060	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUT05_RS34070	COG0477	Major facilitator Superfamily
HUT05_RS34090	COG2197	response regulator
HUT05_RS34100	COG4585	Histidine kinase
HUT05_RS34105	COG2030	dehydratase
HUT05_RS34115	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS34130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUT05_RS34145	COG0800	Aldolase
HUT05_RS34150	COG3022	response to hydroperoxide
HUT05_RS34155	COG0557	exoribonuclease II activity
HUT05_RS34215	COG0745	RESPONSE REGULATOR receiver
HUT05_RS34220	COG2072	flavoprotein involved in K transport
HUT05_RS34250	COG2259	Doxx family
HUT05_RS34260	COG0667	Aldo Keto reductase
HUT05_RS34265	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS34270	COG3540	Alkaline phosphatase
HUT05_RS34280	COG2814	Major facilitator Superfamily
HUT05_RS34285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT05_RS34315	COG0672	)-iron permease
HUT05_RS34320	COG2837	iron assimilation
HUT05_RS34330	COG1120	ATPase activity
HUT05_RS34335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS34340	COG4558	Periplasmic binding protein
HUT05_RS34405	COG1994	Peptidase M50
HUT05_RS34425	COG2814	Major facilitator Superfamily
HUT05_RS34440	COG0477	Major facilitator Superfamily
HUT05_RS34445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT05_RS34480	COG0174	glutamine synthetase
HUT05_RS34485	COG1017	nitric oxide dioxygenase activity
HUT05_RS34485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT05_RS34490	COG1959	2 iron, 2 sulfur cluster binding
HUT05_RS34535	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT05_RS34545	COG1609	Transcriptional regulator
HUT05_RS34555	COG1175	transmembrane transport
HUT05_RS34560	COG3833	ABC-type maltose transport systems, permease component
HUT05_RS34565	COG0366	Alpha amylase catalytic
HUT05_RS34630	COG2197	response regulator
HUT05_RS34635	COG4585	Histidine kinase
HUT05_RS34645	COG0745	RESPONSE REGULATOR receiver
HUT05_RS34700	COG0501	Belongs to the peptidase M48B family
HUT05_RS34835	COG0582	viral genome integration into host DNA
HUT05_RS34840	COG0174	glutamine synthetase
HUT05_RS34860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT05_RS34865	COG0321	lipoyl(octanoyl) transferase activity
HUT05_RS34880	COG1090	epimerase
HUT05_RS34885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT05_RS34920	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT05_RS34930	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT05_RS34935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT05_RS34940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT05_RS34965	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUT05_RS34980	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT05_RS35000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT05_RS35025	COG4585	Histidine kinase
HUT05_RS35030	COG2197	response regulator
HUT05_RS35035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT05_RS35045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUT05_RS35065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS35075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT05_RS35080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT05_RS35090	COG1376	ErfK ybiS ycfS ynhG family protein
HUT05_RS35100	COG1845	cytochrome c oxidase, subunit III
HUT05_RS35105	COG2010	Cytochrome c
HUT05_RS35110	COG0723	plastoquinol--plastocyanin reductase activity
HUT05_RS35115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT05_RS35120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUT05_RS35125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT05_RS35130	COG1929	Belongs to the glycerate kinase type-1 family
HUT05_RS35140	COG0745	RESPONSE REGULATOR receiver
HUT05_RS35145	COG2205	protein histidine kinase activity
HUT05_RS35215	COG0003	Pfam Anion-transporting ATPase
HUT05_RS35225	COG1940	carbohydrate kinase activity
HUT05_RS35250	COG4585	Histidine kinase
HUT05_RS35260	COG0205	6-phosphofructokinase activity
HUT05_RS35265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT05_RS35280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT05_RS35285	COG0243	molybdopterin cofactor binding
HUT05_RS35290	COG2193	ferroxidase activity
HUT05_RS35295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT05_RS35305	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HUT05_RS35310	COG2815	serine threonine protein kinase
HUT05_RS35310	COG0515	serine threonine protein kinase
HUT05_RS35315	COG2022	thiamine diphosphate biosynthetic process
HUT05_RS35325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT05_RS35325	COG2022	thiamine diphosphate biosynthetic process
HUT05_RS35345	COG0352	thiamine-phosphate diphosphorylase activity
HUT05_RS35370	COG1309	transcriptional regulator
HUT05_RS35380	COG3842	ATPase activity
HUT05_RS35390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT05_RS35410	COG0714	Associated with various cellular activities
HUT05_RS35420	COG0275	rRNA processing
HUT05_RS35435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT05_RS35445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT05_RS35450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT05_RS35460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT05_RS35465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUT05_RS35470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUT05_RS35485	COG1799	cell septum assembly
HUT05_RS35495	COG3599	regulation of cell shape
HUT05_RS35500	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT05_RS35510	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT05_RS35570	COG0587	DNA-directed DNA polymerase activity
HUT05_RS35580	COG1432	Conserved Protein
HUT05_RS35600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUT05_RS35605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT05_RS35620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT05_RS35625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT05_RS35630	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT05_RS35640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUT05_RS35645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT05_RS35650	COG0251	oxidation-reduction process
HUT05_RS35655	COG0107	imidazoleglycerol-phosphate synthase activity
HUT05_RS35675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUT05_RS35680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT05_RS35700	COG0134	indole-3-glycerol-phosphate synthase activity
HUT05_RS35710	COG0133	tryptophan synthase activity
HUT05_RS35715	COG0159	tryptophan synthase activity
HUT05_RS35725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT05_RS35735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT05_RS35740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT05_RS35760	COG1397	ADP-ribosylglycohydrolase
HUT05_RS35770	COG0070	glutamate synthase
HUT05_RS35770	COG0069	glutamate synthase activity
HUT05_RS35770	COG0067	glutamate synthase
HUT05_RS35790	COG2304	oxidoreductase activity
HUT05_RS35795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT05_RS35805	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS35810	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS35815	COG1309	transcriptional regulator
HUT05_RS35820	COG0183	Belongs to the thiolase family
HUT05_RS35840	COG1024	Enoyl-CoA hydratase
HUT05_RS35850	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS35860	COG5640	endopeptidase activity
HUT05_RS35875	COG1605	Chorismate mutase
HUT05_RS35875	COG0287	Prephenate dehydrogenase
HUT05_RS35880	COG0745	RESPONSE REGULATOR receiver
HUT05_RS35910	COG0737	Belongs to the 5'-nucleotidase family
HUT05_RS35940	COG0411	ABC transporter
HUT05_RS35965	COG2050	protein possibly involved in aromatic compounds catabolism
HUT05_RS36005	COG1643	Atp-dependent helicase
HUT05_RS36025	COG0237	dephospho-CoA kinase activity
HUT05_RS36060	COG2267	carboxylic ester hydrolase activity
HUT05_RS36065	COG1802	Transcriptional regulator
HUT05_RS36070	COG1953	Uracil, thiamine, allantoin
HUT05_RS36080	COG0456	acetyltransferase
HUT05_RS36110	COG0402	S-adenosylhomocysteine deaminase activity
HUT05_RS36115	COG2124	cytochrome p450
HUT05_RS36160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT05_RS36165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT05_RS36200	COG0598	Magnesium transport protein CorA
HUT05_RS36205	COG2226	methyltransferase
HUT05_RS36210	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUT05_RS36210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUT05_RS36215	COG2313	pseudouridylate synthase activity
HUT05_RS36225	COG1063	alcohol dehydrogenase
HUT05_RS36235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT05_RS36240	COG0584	glycerophosphoryl diester phosphodiesterase
HUT05_RS36250	COG0556	nucleotide-excision repair
HUT05_RS36275	COG0387	Pfam Sodium calcium exchanger
HUT05_RS36280	COG0477	Major facilitator Superfamily
HUT05_RS36285	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT05_RS36290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT05_RS36295	COG1126	abc transporter atp-binding protein
HUT05_RS36300	COG0765	amino acid transport
HUT05_RS36305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT05_RS36320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT05_RS36340	COG0322	excinuclease ABC activity
HUT05_RS36345	COG1660	Displays ATPase and GTPase activities
HUT05_RS36350	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT05_RS36355	COG1481	regulation of sporulation
HUT05_RS36365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT05_RS36370	COG0126	phosphoglycerate kinase activity
HUT05_RS36375	COG0149	triose-phosphate isomerase activity
HUT05_RS36380	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUT05_RS36395	COG0166	Belongs to the GPI family
HUT05_RS36410	COG1136	(ABC) transporter
HUT05_RS36415	COG1695	Transcriptional regulator
HUT05_RS36420	COG1653	transport
HUT05_RS36425	COG0366	Alpha amylase catalytic
HUT05_RS36435	COG1175	transmembrane transport
HUT05_RS36440	COG0395	ABC-type sugar transport system, permease component
HUT05_RS36445	COG0363	glucosamine-6-phosphate deaminase activity
HUT05_RS36460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT05_RS36470	COG0109	protoheme IX farnesyltransferase activity
HUT05_RS36485	COG1612	heme a metabolic process
HUT05_RS36495	COG1131	(ABC) transporter
HUT05_RS36500	COG2746	aminoglycoside 3-N-acetyltransferase activity
HUT05_RS36515	COG0719	Fe-S assembly protein
HUT05_RS36525	COG0396	ATPase activity
HUT05_RS36530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT05_RS36535	COG0822	iron-sulfur transferase activity
HUT05_RS36540	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT05_RS36550	COG0583	DNA-binding transcription factor activity
HUT05_RS36570	COG1733	regulation of RNA biosynthetic process
HUT05_RS36575	COG2076	Multidrug Resistance protein
HUT05_RS36580	COG3226	Transcriptional regulator
HUT05_RS36595	COG2171	N-acyltransferase activity
HUT05_RS36605	COG1595	DNA-templated transcription, initiation
HUT05_RS36615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT05_RS36620	COG0321	lipoyl(octanoyl) transferase activity
HUT05_RS36680	COG1802	Transcriptional regulator
HUT05_RS36690	COG1609	Transcriptional regulator
HUT05_RS36700	COG1063	alcohol dehydrogenase
HUT05_RS36725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT05_RS36730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT05_RS36760	COG1802	Transcriptional regulator
HUT05_RS36765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT05_RS36775	COG1175	transmembrane transport
HUT05_RS36780	COG0395	ABC-type sugar transport system, permease component
HUT05_RS36800	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT05_RS36815	COG2755	lipolytic protein G-D-S-L family
HUT05_RS36825	COG4677	pectinesterase activity
HUT05_RS36840	COG5297	Belongs to the glycosyl hydrolase family 6
HUT05_RS36850	COG1595	DNA-templated transcription, initiation
HUT05_RS36855	COG2252	PERMEase
HUT05_RS36860	COG0768	penicillin binding
HUT05_RS36865	COG2197	response regulator
HUT05_RS36870	COG4585	Histidine kinase
HUT05_RS36885	COG1414	Transcriptional regulator
HUT05_RS36895	COG2197	response regulator
HUT05_RS36900	COG4585	Histidine kinase
HUT05_RS36920	COG4977	sequence-specific DNA binding
HUT05_RS36920	COG1917	Cupin 2, conserved barrel domain protein
HUT05_RS36935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT05_RS36950	COG5285	phytanoyl-CoA dioxygenase
HUT05_RS36955	COG1917	Cupin 2, conserved barrel domain protein
HUT05_RS36960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUT05_RS36965	COG0456	acetyltransferase
HUT05_RS36970	COG2318	DinB family
HUT05_RS36975	COG1104	cysteine desulfurase activity
HUT05_RS36985	COG0765	amino acid transport
HUT05_RS37040	COG1797	cobyrinic acid a,c-diamide synthase activity
HUT05_RS37060	COG1492	cobalamin metabolic process
HUT05_RS37065	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT05_RS37085	COG0235	Class ii aldolase
HUT05_RS37105	COG0488	(ABC) transporter
HUT05_RS37155	COG3387	PFAM Glycoside hydrolase 15-related
HUT05_RS37180	COG1966	Carbon starvation protein
HUT05_RS37195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT05_RS37215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT05_RS37230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT05_RS37235	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT05_RS37255	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT05_RS37265	COG0312	modulator of DNA gyrase
HUT05_RS37270	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS37285	COG2186	Transcriptional regulator
HUT05_RS37290	COG2807	transmembrane transport
HUT05_RS37300	COG0588	phosphoglycerate mutase activity
HUT05_RS37305	COG3830	Belongs to the UPF0237 family
HUT05_RS37305	COG0560	Phosphoserine phosphatase
HUT05_RS37315	COG1131	(ABC) transporter
HUT05_RS37315	COG0842	Transport permease protein
HUT05_RS37315	COG1716	ATPase activity
HUT05_RS37325	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUT05_RS37330	COG4221	oxidoreductase activity
HUT05_RS37340	COG2197	response regulator
HUT05_RS37355	COG1119	ATPase activity
HUT05_RS37375	COG1881	PFAM PEBP family protein
HUT05_RS37420	COG0647	UMP catabolic process
HUT05_RS37425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS37430	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS37435	COG1120	ATPase activity
HUT05_RS37455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT05_RS37460	COG0497	DNA recombination
HUT05_RS37470	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS37470	COG0297	glycogen (starch) synthase activity
HUT05_RS37485	COG3387	PFAM Glycoside hydrolase 15-related
HUT05_RS37490	COG0504	CTP synthase activity
HUT05_RS37495	COG0494	nUDIX hydrolase
HUT05_RS37505	COG0686	Belongs to the AlaDH PNT family
HUT05_RS37520	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUT05_RS37525	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT05_RS37530	COG1187	pseudouridine synthase activity
HUT05_RS37545	COG0477	Major facilitator Superfamily
HUT05_RS37550	COG0494	nUDIX hydrolase
HUT05_RS37560	COG3541	Predicted nucleotidyltransferase
HUT05_RS37585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUT05_RS37595	COG1160	GTP binding
HUT05_RS37610	COG3583	domain protein
HUT05_RS37615	COG3583	domain protein
HUT05_RS37625	COG0411	ABC transporter
HUT05_RS37665	COG0671	phosphoesterase, PA-phosphatase related
HUT05_RS37670	COG0477	Major facilitator Superfamily
HUT05_RS37675	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS37680	COG1799	cell septum assembly
HUT05_RS37695	COG0330	HflC and HflK could
HUT05_RS37710	COG0587	DNA-directed DNA polymerase activity
HUT05_RS37715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT05_RS37770	COG1725	Transcriptional regulator
HUT05_RS37795	COG1649	PFAM Uncharacterised BCR, COG1649
HUT05_RS37795	COG0726	polysaccharide deacetylase
HUT05_RS37825	COG2755	lipolytic protein G-D-S-L family
HUT05_RS37830	COG2815	serine threonine protein kinase
HUT05_RS37830	COG0515	serine threonine protein kinase
HUT05_RS37910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT05_RS37935	COG1819	glycosyl
HUT05_RS37945	COG1131	(ABC) transporter
HUT05_RS38015	COG0604	alcohol dehydrogenase
HUT05_RS38015	COG3321	synthase
HUT05_RS38035	COG3321	synthase
HUT05_RS38035	COG0604	alcohol dehydrogenase
HUT05_RS38060	COG1595	DNA-templated transcription, initiation
HUT05_RS38095	COG2188	Transcriptional regulator
HUT05_RS38100	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUT05_RS38110	COG1309	transcriptional regulator
HUT05_RS38115	COG0243	molybdopterin cofactor binding
HUT05_RS38120	COG2851	Citrate transporter
HUT05_RS38170	COG0640	Transcriptional regulator
HUT05_RS38180	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS38230	COG3876	Protein conserved in bacteria
HUT05_RS38240	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS38250	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS38275	COG2149	membrane
HUT05_RS38280	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT05_RS38315	COG1063	alcohol dehydrogenase
HUT05_RS38320	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS38330	COG3265	gluconokinase activity
HUT05_RS38335	COG2186	Transcriptional regulator
HUT05_RS38345	COG3012	SEC-C Motif Domain Protein
HUT05_RS38350	COG0308	aminopeptidase N
HUT05_RS38370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS38400	COG0667	Aldo Keto reductase
HUT05_RS38405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS38415	COG0598	Magnesium transport protein CorA
HUT05_RS38420	COG0588	phosphoglycerate mutase activity
HUT05_RS38435	COG0215	cysteine-tRNA ligase activity
HUT05_RS38465	COG2186	Transcriptional regulator
HUT05_RS38475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT05_RS38480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT05_RS38485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT05_RS38490	COG1414	Transcriptional regulator
HUT05_RS38495	COG1410	methionine synthase
HUT05_RS38495	COG0646	methionine synthase
HUT05_RS38500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT05_RS38505	COG0747	negative chemotaxis
HUT05_RS38510	COG0747	negative chemotaxis
HUT05_RS38515	COG2197	response regulator
HUT05_RS38525	COG0517	IMP dehydrogenase activity
HUT05_RS38525	COG1994	Peptidase M50
HUT05_RS38545	COG1222	aaa ATPase
HUT05_RS38550	COG4122	O-methyltransferase activity
HUT05_RS38565	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT05_RS38570	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT05_RS38575	COG1609	Transcriptional regulator
HUT05_RS38585	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT05_RS38620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT05_RS38625	COG0805	protein transport
HUT05_RS38635	COG3973	AAA domain
HUT05_RS38665	COG0564	pseudouridine synthase activity
HUT05_RS38700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT05_RS38705	COG4175	Glycine betaine
HUT05_RS38705	COG0517	IMP dehydrogenase activity
HUT05_RS38710	COG4176	ABC-type proline glycine betaine transport system permease component
HUT05_RS38720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT05_RS38735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT05_RS38740	COG0531	amino acid
HUT05_RS38750	COG0174	glutamine synthetase
HUT05_RS38755	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS38760	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS38805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUT05_RS38810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUT05_RS38815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT05_RS38820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT05_RS38825	COG5002	protein histidine kinase activity
HUT05_RS38830	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT05_RS38835	COG0072	phenylalanine-tRNA ligase activity
HUT05_RS38835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT05_RS38865	COG1649	PFAM Uncharacterised BCR, COG1649
HUT05_RS38875	COG0697	spore germination
HUT05_RS38910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT05_RS38915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUT05_RS38920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT05_RS38925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT05_RS38930	COG1438	arginine binding
HUT05_RS38965	COG0165	Argininosuccinate lyase
HUT05_RS38980	COG0477	Major facilitator Superfamily
HUT05_RS38985	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS38985	COG0204	Acyl-transferase
HUT05_RS38990	COG0584	glycerophosphoryl diester phosphodiesterase
HUT05_RS39015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT05_RS39020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT05_RS39025	COG2011	ABC-type metal ion transport system permease component
HUT05_RS39030	COG1464	Belongs to the NlpA lipoprotein family
HUT05_RS39045	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT05_RS39050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT05_RS39050	COG1648	precorrin-2 dehydrogenase activity
HUT05_RS39060	COG0494	nUDIX hydrolase
HUT05_RS39115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT05_RS39125	COG0456	acetyltransferase
HUT05_RS39125	COG0454	-acetyltransferase
HUT05_RS39170	COG1175	transmembrane transport
HUT05_RS39175	COG0395	ABC-type sugar transport system, permease component
HUT05_RS39265	COG1073	alpha beta
HUT05_RS39325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUT05_RS39340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT05_RS39345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT05_RS39365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUT05_RS39370	COG1560	Kdo2-lipid A biosynthetic process
HUT05_RS39375	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS39385	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUT05_RS39390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUT05_RS39395	COG0217	transcriptional regulatory protein
HUT05_RS39400	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUT05_RS39405	COG0632	four-way junction helicase activity
HUT05_RS39410	COG2255	four-way junction helicase activity
HUT05_RS39420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT05_RS39425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT05_RS39430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT05_RS39435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT05_RS39440	COG1196	nuclear chromosome segregation
HUT05_RS39445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUT05_RS39455	COG0124	histidyl-tRNA synthetase
HUT05_RS39470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT05_RS39490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT05_RS39495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUT05_RS39500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUT05_RS39505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT05_RS39515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT05_RS39520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT05_RS39525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT05_RS39535	COG0006	proline dipeptidase activity
HUT05_RS39540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT05_RS39545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT05_RS39555	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUT05_RS39560	COG0540	Belongs to the ATCase OTCase family
HUT05_RS39565	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT05_RS39575	COG0505	Belongs to the CarA family
HUT05_RS39580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT05_RS39585	COG0167	dihydroorotate dehydrogenase activity
HUT05_RS39590	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT05_RS39600	COG0194	GDP metabolic process
HUT05_RS39605	COG1758	RNA polymerase activity
HUT05_RS39615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT05_RS39630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT05_RS39640	COG2409	Drug exporters of the RND superfamily
HUT05_RS39645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUT05_RS39650	COG2390	Transcriptional regulator
HUT05_RS39665	COG0531	amino acid
HUT05_RS39680	COG2188	Transcriptional regulator
HUT05_RS39690	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT05_RS39700	COG3842	ATPase activity
HUT05_RS39705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT05_RS39720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT05_RS39745	COG2233	PERMEase
HUT05_RS39755	COG0738	Major facilitator superfamily
HUT05_RS39760	COG1940	carbohydrate kinase activity
HUT05_RS39760	COG1846	Transcriptional regulator
HUT05_RS39765	COG1090	epimerase
HUT05_RS39780	COG3201	nicotinamide mononucleotide transporter
HUT05_RS39785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT05_RS39785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT05_RS39790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT05_RS39795	COG0140	phosphoribosyl-ATP diphosphatase activity
HUT05_RS39800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT05_RS39860	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS39895	COG1216	Glycosyl transferase, family 2
HUT05_RS39910	COG2270	Major facilitator Superfamily
HUT05_RS39920	COG2364	Membrane
HUT05_RS39925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT05_RS39960	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS39965	COG2755	lipolytic protein G-D-S-L family
HUT05_RS39970	COG1984	allophanate hydrolase subunit 2
HUT05_RS39975	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUT05_RS39980	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HUT05_RS39985	COG4336	lyase activity
HUT05_RS39990	COG2814	Major facilitator Superfamily
HUT05_RS40015	COG0531	amino acid
HUT05_RS40035	COG2018	Roadblock/LC7 domain
HUT05_RS40055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT05_RS40060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT05_RS40070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT05_RS40080	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT05_RS40095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT05_RS40105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT05_RS40135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT05_RS40175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT05_RS40185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT05_RS40185	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT05_RS40205	COG0531	amino acid
HUT05_RS40220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT05_RS40225	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT05_RS40230	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT05_RS40265	COG1175	transmembrane transport
HUT05_RS40270	COG0395	ABC-type sugar transport system, permease component
HUT05_RS40315	COG0384	phenazine biosynthesis protein PhzF
HUT05_RS40380	COG0697	spore germination
HUT05_RS40425	COG0747	negative chemotaxis
HUT05_RS40430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT05_RS40445	COG2318	DinB family
HUT05_RS40465	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HUT05_RS40500	COG1968	undecaprenyl-diphosphatase activity
HUT05_RS40520	COG0183	Belongs to the thiolase family
HUT05_RS40590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT05_RS40640	COG0640	Transcriptional regulator
HUT05_RS40650	COG1832	CoA-binding protein
HUT05_RS40655	COG0215	cysteine-tRNA ligase activity
HUT05_RS40665	COG1739	Uncharacterized protein family UPF0029
HUT05_RS40670	COG0420	3'-5' exonuclease activity
HUT05_RS40675	COG0419	ATPase involved in DNA repair
HUT05_RS40690	COG1522	sequence-specific DNA binding
HUT05_RS40705	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS40720	COG0626	cystathionine gamma-synthase activity
HUT05_RS40790	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HUT05_RS40790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT05_RS40800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT05_RS40830	COG0475	glutathione-regulated potassium exporter activity
HUT05_RS40850	COG1595	DNA-templated transcription, initiation
HUT05_RS40855	COG2188	Transcriptional regulator
HUT05_RS40860	COG1940	carbohydrate kinase activity
HUT05_RS40865	COG2197	response regulator
HUT05_RS40870	COG4585	Histidine kinase
HUT05_RS40890	COG3663	DNA glycosylase
HUT05_RS40895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT05_RS40920	COG0456	acetyltransferase
HUT05_RS40930	COG0577	efflux transmembrane transporter activity
HUT05_RS40930	COG1136	(ABC) transporter
HUT05_RS40935	COG1136	(ABC) transporter
HUT05_RS40935	COG0577	efflux transmembrane transporter activity
HUT05_RS40950	COG2226	methyltransferase
HUT05_RS40970	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT05_RS40975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT05_RS40980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUT05_RS40985	COG0156	8-amino-7-oxononanoate synthase activity
HUT05_RS41005	COG0583	DNA-binding transcription factor activity
HUT05_RS41010	COG1280	lysine exporter protein (LysE YggA)
HUT05_RS41015	COG0791	NLP P60 protein
HUT05_RS41025	COG0740	serine-type endopeptidase activity
HUT05_RS41040	COG1309	transcriptional regulator
HUT05_RS41045	COG0831	urea catabolic process
HUT05_RS41050	COG0832	Belongs to the urease beta subunit family
HUT05_RS41055	COG0804	urea catabolic process
HUT05_RS41065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT05_RS41070	COG0829	nickel cation binding
HUT05_RS41090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT05_RS41095	COG1834	amidinotransferase
HUT05_RS41100	COG1522	sequence-specific DNA binding
HUT05_RS41105	COG3279	Response regulator of the LytR AlgR family
HUT05_RS41115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT05_RS41120	COG3275	phosphorelay sensor kinase activity
HUT05_RS41130	COG2815	serine threonine protein kinase
HUT05_RS41130	COG0515	serine threonine protein kinase
HUT05_RS41145	COG0205	6-phosphofructokinase activity
HUT05_RS41150	COG3442	glutamine amidotransferase
HUT05_RS41160	COG0242	peptide deformylase activity
HUT05_RS41170	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS41185	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS41195	COG1793	dna ligase
HUT05_RS41200	COG3118	belongs to the thioredoxin family
HUT05_RS41200	COG0492	ferredoxin-NADP+ reductase activity
HUT05_RS41215	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS41220	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS41235	COG4632	Exopolysaccharide biosynthesis protein
HUT05_RS41235	COG5434	Belongs to the glycosyl hydrolase 28 family
HUT05_RS41250	COG2124	cytochrome p450
HUT05_RS41260	COG0586	Pfam SNARE associated Golgi protein
HUT05_RS41265	COG4214	carbohydrate transport
HUT05_RS41275	COG4213	ABC transporter substrate-binding protein
HUT05_RS41285	COG4213	ABC transporter substrate-binding protein
HUT05_RS41310	COG1082	Xylose isomerase domain protein TIM barrel
HUT05_RS41330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS41360	COG0515	serine threonine protein kinase
HUT05_RS41360	COG2815	serine threonine protein kinase
HUT05_RS41380	COG3631	Ketosteroid isomerase-related protein
HUT05_RS41385	COG0702	epimerase
HUT05_RS41390	COG0488	(ABC) transporter
HUT05_RS41395	COG0488	(ABC) transporter
HUT05_RS41415	COG0210	DNA helicase
HUT05_RS41425	COG1401	restriction endodeoxyribonuclease activity
HUT05_RS41430	COG3550	peptidyl-serine autophosphorylation
HUT05_RS41455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT05_RS41485	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HUT05_RS41580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUT05_RS41590	COG0515	serine threonine protein kinase
HUT05_RS41590	COG2815	serine threonine protein kinase
HUT05_RS41615	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS41635	COG1113	amino acid transport
HUT05_RS41670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT05_RS41740	COG2018	Roadblock/LC7 domain
HUT05_RS41750	COG1946	Acyl-CoA thioesterase
HUT05_RS41765	COG0254	rRNA binding
HUT05_RS41775	COG1132	(ABC) transporter
HUT05_RS41780	COG1132	(ABC) transporter
HUT05_RS41795	COG1301	dicarboxylic acid transport
HUT05_RS41805	COG1132	(ABC) transporter
HUT05_RS41815	COG2072	flavoprotein involved in K transport
HUT05_RS41825	COG1116	anion transmembrane transporter activity
HUT05_RS41830	COG0432	Pfam Uncharacterised protein family UPF0047
HUT05_RS41835	COG1653	transport
HUT05_RS41845	COG2197	response regulator
HUT05_RS41855	COG1136	(ABC) transporter
HUT05_RS41855	COG0577	efflux transmembrane transporter activity
HUT05_RS41865	COG1653	transport
HUT05_RS41930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS41935	COG1120	ATPase activity
HUT05_RS41940	COG2814	Major facilitator Superfamily
HUT05_RS41945	COG0367	asparagine synthase
HUT05_RS41965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HUT05_RS41970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS42015	COG1082	Xylose isomerase domain protein TIM barrel
HUT05_RS42020	COG0673	inositol 2-dehydrogenase activity
HUT05_RS42025	COG2814	Major facilitator Superfamily
HUT05_RS42035	COG1609	Transcriptional regulator
HUT05_RS42050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT05_RS42080	COG1222	aaa ATPase
HUT05_RS42170	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HUT05_RS42190	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS42195	COG0517	IMP dehydrogenase activity
HUT05_RS42195	COG4175	Glycine betaine
HUT05_RS42200	COG4176	ABC-type proline glycine betaine transport system permease component
HUT05_RS42215	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT05_RS42245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT05_RS42260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT05_RS42315	COG1126	abc transporter atp-binding protein
HUT05_RS42320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT05_RS42325	COG0765	amino acid transport
HUT05_RS42330	COG0765	amino acid transport
HUT05_RS42385	COG0604	alcohol dehydrogenase
HUT05_RS42385	COG3321	synthase
HUT05_RS42415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT05_RS42420	COG1760	l-serine dehydratase
HUT05_RS42425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT05_RS42430	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS42440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT05_RS42455	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS42465	COG4585	Histidine kinase
HUT05_RS42470	COG2197	response regulator
HUT05_RS42480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT05_RS42490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS42495	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HUT05_RS42505	COG1175	transmembrane transport
HUT05_RS42520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT05_RS42585	COG2340	Cysteine-rich secretory protein family
HUT05_RS42590	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS42600	COG3842	ATPase activity
HUT05_RS42605	COG1177	transmembrane transport
HUT05_RS42610	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT05_RS42640	COG1042	CoA-binding domain protein
HUT05_RS42640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT05_RS42640	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT05_RS42645	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS42660	COG1309	transcriptional regulator
HUT05_RS42680	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HUT05_RS42695	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS42700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS42705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT05_RS42715	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HUT05_RS42735	COG3291	Pkd domain containing protein
HUT05_RS42775	COG3340	Belongs to the peptidase S51 family
HUT05_RS42790	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS42800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HUT05_RS42820	COG0395	ABC-type sugar transport system, permease component
HUT05_RS42825	COG1175	transmembrane transport
HUT05_RS42855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT05_RS42860	COG1993	acr, cog1993
HUT05_RS42865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT05_RS42870	COG1968	undecaprenyl-diphosphatase activity
HUT05_RS42875	COG2186	Transcriptional regulator
HUT05_RS42880	COG1113	amino acid transport
HUT05_RS42895	COG2066	Belongs to the glutaminase family
HUT05_RS42910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HUT05_RS42925	COG1695	Transcriptional regulator
HUT05_RS42950	COG3458	cephalosporin-C deacetylase activity
HUT05_RS42970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT05_RS42975	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT05_RS42985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT05_RS42990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT05_RS43010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS43015	COG1902	pentaerythritol trinitrate reductase activity
HUT05_RS43015	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT05_RS43040	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS43055	COG1461	Dihydroxyacetone kinase
HUT05_RS43060	COG2376	Dihydroxyacetone kinase
HUT05_RS43090	COG2326	polyphosphate kinase activity
HUT05_RS43105	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS43115	COG0515	serine threonine protein kinase
HUT05_RS43135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT05_RS43140	COG2070	2-Nitropropane dioxygenase
HUT05_RS43160	COG2124	cytochrome p450
HUT05_RS43170	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS43220	COG1024	Enoyl-CoA hydratase
HUT05_RS43245	COG0589	response to stress
HUT05_RS43340	COG0640	Transcriptional regulator
HUT05_RS43360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT05_RS43365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT05_RS43400	COG0702	epimerase
HUT05_RS43405	COG1846	Transcriptional regulator
HUT05_RS43410	COG2409	Drug exporters of the RND superfamily
HUT05_RS43430	COG4941	Belongs to the sigma-70 factor family
HUT05_RS43435	COG2188	Transcriptional regulator
HUT05_RS43460	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT05_RS43495	COG1309	transcriptional regulator
HUT05_RS43515	COG0183	Belongs to the thiolase family
HUT05_RS43520	COG1024	Enoyl-CoA hydratase
HUT05_RS43525	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT05_RS43545	COG0667	Aldo Keto reductase
HUT05_RS43560	COG0346	lactoylglutathione lyase activity
HUT05_RS43565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT05_RS43575	COG0583	DNA-binding transcription factor activity
HUT05_RS43580	COG0667	Aldo Keto reductase
HUT05_RS43600	COG1716	ATPase activity
HUT05_RS43600	COG1131	(ABC) transporter
HUT05_RS43600	COG0842	Transport permease protein
HUT05_RS43630	COG2318	DinB family
HUT05_RS43635	COG1396	sequence-specific DNA binding
HUT05_RS43640	COG0740	serine-type endopeptidase activity
HUT05_RS43645	COG0740	serine-type endopeptidase activity
HUT05_RS43650	COG0596	Alpha beta hydrolase
HUT05_RS43665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT05_RS43675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT05_RS43690	COG0328	RNA-DNA hybrid ribonuclease activity
HUT05_RS43695	COG2304	oxidoreductase activity
HUT05_RS43710	COG0667	Aldo Keto reductase
HUT05_RS43725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS43735	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT05_RS43735	COG0515	serine threonine protein kinase
HUT05_RS43760	COG2340	Cysteine-rich secretory protein family
HUT05_RS43770	COG1940	carbohydrate kinase activity
HUT05_RS43770	COG1846	Transcriptional regulator
HUT05_RS43775	COG3345	alpha-galactosidase
HUT05_RS43790	COG1672	PFAM Archaeal ATPase
HUT05_RS43790	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT05_RS43820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT05_RS43860	COG5002	protein histidine kinase activity
HUT05_RS43930	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT05_RS43935	COG3281	Trehalose synthase
HUT05_RS44000	COG0181	hydroxymethylbilane synthase activity
HUT05_RS44025	COG2197	response regulator
HUT05_RS44040	COG0745	RESPONSE REGULATOR receiver
HUT05_RS44065	COG2223	nitrite transmembrane transporter activity
HUT05_RS44070	COG2207	Transcriptional regulator
HUT05_RS44090	COG0656	L-ascorbic acid biosynthetic process
HUT05_RS44095	COG1609	Transcriptional regulator
HUT05_RS44100	COG1621	beta-fructofuranosidase activity
HUT05_RS44105	COG0395	ABC-type sugar transport system, permease component
HUT05_RS44110	COG1175	transmembrane transport
HUT05_RS44120	COG1621	beta-fructofuranosidase activity
HUT05_RS44130	COG0596	Alpha beta hydrolase
HUT05_RS44140	COG3903	Transcriptional regulator
HUT05_RS44140	COG3629	intracellular signal transduction
HUT05_RS44175	COG0596	Alpha beta hydrolase
HUT05_RS44190	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS44200	COG0009	L-threonylcarbamoyladenylate synthase
HUT05_RS44220	COG3845	ABC transporter
HUT05_RS44250	COG3320	Male sterility
HUT05_RS44250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT05_RS44265	COG0640	Transcriptional regulator
HUT05_RS44295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT05_RS44305	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT05_RS44310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS44315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT05_RS44320	COG1120	ATPase activity
HUT05_RS44330	COG1132	(ABC) transporter
HUT05_RS44340	COG1132	(ABC) transporter
HUT05_RS44345	COG2382	esterase
HUT05_RS44365	COG0277	FAD linked oxidase domain protein
HUT05_RS44370	COG4689	acetoacetate decarboxylase
HUT05_RS44375	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS44385	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT05_RS44400	COG1012	belongs to the aldehyde dehydrogenase family
HUT05_RS44405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT05_RS44410	COG1846	Transcriptional regulator
HUT05_RS44425	COG0765	amino acid transport
HUT05_RS44445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS44455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS44465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS44480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT05_RS44750	COG2124	cytochrome p450
HUT05_RS44770	COG0738	Major facilitator superfamily
HUT05_RS44860	COG0358	DNA primase activity
HUT05_RS45005	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT05_RS45025	COG0717	Belongs to the dCTP deaminase family
HUT05_RS45040	COG0297	glycogen (starch) synthase activity
HUT05_RS45045	COG0442	prolyl-tRNA aminoacylation
HUT05_RS45055	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT05_RS45100	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS45120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT05_RS45185	COG0640	Transcriptional regulator
HUT05_RS45260	COG0463	Glycosyl transferase, family 2
HUT05_RS45275	COG1017	nitric oxide dioxygenase activity
HUT05_RS45275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT05_RS45285	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS45325	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS45370	COG0741	lytic transglycosylase activity
HUT05_RS45370	COG1196	nuclear chromosome segregation
HUT05_RS45370	COG0739	heme binding
HUT05_RS45380	COG1864	DNA RNA non-specific endonuclease
HUT05_RS45380	COG3591	Belongs to the peptidase S1B family
HUT05_RS45410	COG3655	Transcriptional regulator
HUT05_RS45420	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS45425	COG0583	DNA-binding transcription factor activity
HUT05_RS45430	COG0488	(ABC) transporter
HUT05_RS45435	COG1404	Belongs to the peptidase S8 family
HUT05_RS45440	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT05_RS45440	COG2319	Wd-40 repeat
HUT05_RS45450	COG3033	Beta-eliminating lyase
HUT05_RS45465	COG2188	Transcriptional regulator
HUT05_RS45475	COG1175	transmembrane transport
HUT05_RS45480	COG0395	ABC-type sugar transport system, permease component
HUT05_RS45505	COG1131	(ABC) transporter
HUT05_RS45510	COG2197	response regulator
HUT05_RS45515	COG4585	Histidine kinase
HUT05_RS45545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT05_RS45560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT05_RS45590	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS45605	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT05_RS45650	COG2329	Antibiotic biosynthesis monooxygenase
HUT05_RS45730	COG0596	Alpha beta hydrolase
HUT05_RS45820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT05_RS45840	COG0395	ABC-type sugar transport system, permease component
HUT05_RS45850	COG1191	sigma factor activity
HUT05_RS45870	COG0604	alcohol dehydrogenase
HUT05_RS45920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUT05_RS45980	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS45985	COG3250	beta-galactosidase activity
HUT05_RS45990	COG0477	Major facilitator Superfamily
HUT05_RS46000	COG2226	methyltransferase
HUT05_RS46040	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT05_RS46040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT05_RS46080	COG2814	Major facilitator Superfamily
HUT05_RS46090	COG0583	DNA-binding transcription factor activity
HUT05_RS46095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT05_RS46155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT05_RS46165	COG0473	3-isopropylmalate dehydrogenase activity
HUT05_RS46170	COG0583	DNA-binding transcription factor activity
HUT05_RS46215	COG0395	ABC-type sugar transport system, permease component
HUT05_RS46220	COG1175	transmembrane transport
HUT05_RS46275	COG2318	DinB family
HUT05_RS46285	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT05_RS46290	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT05_RS46295	COG1129	ABC transporter
HUT05_RS46300	COG1879	ABC-type sugar transport system periplasmic component
HUT05_RS46305	COG1609	Transcriptional regulator
HUT05_RS46350	COG0542	response to heat
HUT05_RS46355	COG2837	iron assimilation
HUT05_RS46360	COG2197	response regulator
HUT05_RS46375	COG2409	Drug exporters of the RND superfamily
HUT05_RS46390	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS46405	COG1295	ribonuclease BN
HUT05_RS46410	COG2186	Transcriptional regulator
HUT05_RS46425	COG1175	transmembrane transport
HUT05_RS46430	COG0395	ABC-type sugar transport system, permease component
HUT05_RS46455	COG5002	protein histidine kinase activity
HUT05_RS46455	COG0784	Response regulator, receiver
HUT05_RS46455	COG2205	protein histidine kinase activity
HUT05_RS46470	COG0783	Belongs to the Dps family
HUT05_RS46500	COG1902	pentaerythritol trinitrate reductase activity
HUT05_RS46515	COG0745	RESPONSE REGULATOR receiver
HUT05_RS46520	COG2205	protein histidine kinase activity
HUT05_RS46550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT05_RS46560	COG1024	Enoyl-CoA hydratase
HUT05_RS46570	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS46575	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS46585	COG2124	cytochrome p450
HUT05_RS46625	COG3290	protein histidine kinase activity
HUT05_RS46640	COG0395	ABC-type sugar transport system, permease component
HUT05_RS46645	COG1175	transmembrane transport
HUT05_RS46745	COG0395	ABC-type sugar transport system, permease component
HUT05_RS46750	COG1063	alcohol dehydrogenase
HUT05_RS46755	COG0673	inositol 2-dehydrogenase activity
HUT05_RS46795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT05_RS46800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT05_RS46810	COG0438	transferase activity, transferring glycosyl groups
HUT05_RS46820	COG0789	Transcriptional regulator
HUT05_RS46885	COG1674	ftsk spoiiie
HUT05_RS46890	COG1404	Belongs to the peptidase S8 family
HUT05_RS46895	COG0464	growth
HUT05_RS46960	COG0477	Major facilitator Superfamily
HUT05_RS46965	COG0628	permease
HUT05_RS46970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT05_RS46975	COG0277	FAD linked oxidase domain protein
HUT05_RS46980	COG1309	transcriptional regulator
HUT05_RS47005	COG0411	ABC transporter
HUT05_RS47015	COG2508	Transcriptional regulator
HUT05_RS47050	COG3321	synthase
HUT05_RS47050	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS47050	COG0604	alcohol dehydrogenase
HUT05_RS47070	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
HUT05_RS47080	COG0488	(ABC) transporter
HUT05_RS47085	COG0477	Major facilitator Superfamily
HUT05_RS47090	COG0745	RESPONSE REGULATOR receiver
HUT05_RS47095	COG2205	protein histidine kinase activity
HUT05_RS47120	COG3835	regulator
HUT05_RS47130	COG2080	2 iron, 2 sulfur cluster binding
HUT05_RS47130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT05_RS47145	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUT05_RS47185	COG0235	Class ii aldolase
HUT05_RS47200	COG0300	oxidoreductase activity
HUT05_RS47305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT05_RS47335	COG0640	Transcriptional regulator
HUT05_RS47340	COG0346	lactoylglutathione lyase activity
HUT05_RS47370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT05_RS47380	COG2197	response regulator
HUT05_RS47385	COG3851	Histidine kinase
HUT05_RS47395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUT05_RS47440	COG1233	COG1233 Phytoene dehydrogenase and related
HUT05_RS47465	COG1595	DNA-templated transcription, initiation
HUT05_RS47475	COG1131	(ABC) transporter
HUT05_RS47490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT05_RS47495	COG0583	DNA-binding transcription factor activity
HUT05_RS47500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUT05_RS47575	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS47600	COG0402	S-adenosylhomocysteine deaminase activity
HUT05_RS47630	COG1733	regulation of RNA biosynthetic process
HUT05_RS47695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT05_RS47760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT05_RS47765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT05_RS47770	COG1309	transcriptional regulator
HUT05_RS47780	COG0183	Belongs to the thiolase family
HUT05_RS47785	COG0596	Alpha beta hydrolase
HUT05_RS47825	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS47850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUT05_RS47855	COG1215	transferase activity, transferring glycosyl groups
HUT05_RS47890	COG1349	DNA-binding transcription factor activity
HUT05_RS47915	COG0577	efflux transmembrane transporter activity
HUT05_RS47920	COG1136	(ABC) transporter
HUT05_RS47920	COG0577	efflux transmembrane transporter activity
HUT05_RS47960	COG0698	ribose 5-phosphate isomerase
HUT05_RS47970	COG1940	carbohydrate kinase activity
HUT05_RS47980	COG2813	Specifically methylates the guanine in position
HUT05_RS47990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT05_RS47995	COG1349	DNA-binding transcription factor activity
HUT05_RS48000	COG3387	PFAM Glycoside hydrolase 15-related
HUT05_RS48005	COG3433	isochorismatase activity
HUT05_RS48005	COG1535	isochorismatase
HUT05_RS48015	COG2608	mercury ion transmembrane transporter activity
HUT05_RS48035	COG0395	ABC-type sugar transport system, permease component
HUT05_RS48040	COG1175	transmembrane transport
HUT05_RS48060	COG0673	inositol 2-dehydrogenase activity
HUT05_RS48070	COG1796	DNA polymerase
HUT05_RS48070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT05_RS48090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT05_RS48095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT05_RS48100	COG0019	diaminopimelate decarboxylase activity
HUT05_RS48115	COG0326	Molecular chaperone. Has ATPase activity
HUT05_RS48140	COG3594	Acyltransferase
HUT05_RS48180	COG1228	amidohydrolase
HUT05_RS48190	COG2197	response regulator
HUT05_RS48215	COG0318	PFAM AMP-dependent synthetase and ligase
HUT05_RS48225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT05_RS48225	COG0512	Glutamine amidotransferase of anthranilate synthase
HUT05_RS48240	COG1028	Short-chain dehydrogenase reductase Sdr
HUT05_RS48250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT05_RS48255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT05_RS48265	COG2030	dehydratase
HUT05_RS48280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT05_RS48335	COG2197	response regulator
HUT05_RS48340	COG4585	Histidine kinase
HUT05_RS48360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT05_RS48370	COG1660	Displays ATPase and GTPase activities
HUT05_RS48380	COG1090	epimerase
HUT05_RS48385	COG3345	alpha-galactosidase
HUT05_RS48405	COG0515	serine threonine protein kinase
HUT05_RS48420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT05_RS48445	COG0204	Acyl-transferase
HUT05_RS48480	COG0584	glycerophosphoryl diester phosphodiesterase
HUT05_RS48520	COG0671	phosphoesterase, PA-phosphatase related
HUT05_RS48525	COG0546	phosphoglycolate phosphatase activity
HUT05_RS48550	COG0493	'glutamate synthase
HUT05_RS48560	COG0640	Transcriptional regulator
HUT05_RS48565	COG1902	pentaerythritol trinitrate reductase activity
HUT05_RS48590	COG1960	acyl-CoA dehydrogenase activity
HUT05_RS48605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT05_RS48610	COG2971	BadF BadG BcrA BcrD
HUT05_RS48620	COG2706	6-phosphogluconolactonase activity
HUT05_RS48635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT05_RS48640	COG1404	Belongs to the peptidase S8 family
HUT05_RS48675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT05_RS48680	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT05_RS48685	COG3396	Phenylacetate-CoA oxygenase
HUT05_RS48690	COG3460	Phenylacetate-CoA oxygenase
HUT05_RS48695	COG3396	Phenylacetate-CoA oxygenase