locus-tag	class	description
BB341_RS00005	COG0454	-acetyltransferase
BB341_RS00010	COG1280	lysine exporter protein (LysE YggA)
BB341_RS00040	COG1966	Carbon starvation protein
BB341_RS00065	COG0019	diaminopimelate decarboxylase activity
BB341_RS00090	COG0475	glutathione-regulated potassium exporter activity
BB341_RS00090	COG0569	domain protein
BB341_RS00115	COG2814	Major facilitator Superfamily
BB341_RS00140	COG1063	alcohol dehydrogenase
BB341_RS00145	COG0156	8-amino-7-oxononanoate synthase activity
BB341_RS00155	COG2018	Roadblock/LC7 domain
BB341_RS00170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BB341_RS00190	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS00195	COG0531	amino acid
BB341_RS00205	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS00210	COG0142	geranyltranstransferase activity
BB341_RS00225	COG2124	cytochrome p450
BB341_RS00255	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BB341_RS00270	COG1215	transferase activity, transferring glycosyl groups
BB341_RS00280	COG4310	Domain of unknown function (DUF2172)
BB341_RS00295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BB341_RS00305	COG0438	transferase activity, transferring glycosyl groups
BB341_RS00305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BB341_RS00340	COG0438	transferase activity, transferring glycosyl groups
BB341_RS00345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BB341_RS00380	COG0473	3-isopropylmalate dehydrogenase activity
BB341_RS00425	COG1846	Transcriptional regulator
BB341_RS00440	COG0542	response to heat
BB341_RS00445	COG2172	sigma factor antagonist activity
BB341_RS00445	COG2208	phosphoserine phosphatase activity
BB341_RS00445	COG1366	Belongs to the anti-sigma-factor antagonist family
BB341_RS00460	COG1653	transport
BB341_RS00465	COG1233	COG1233 Phytoene dehydrogenase and related
BB341_RS00490	COG1233	COG1233 Phytoene dehydrogenase and related
BB341_RS00495	COG2130	NADP-dependent
BB341_RS00500	COG2376	Dihydroxyacetone kinase
BB341_RS00505	COG2376	Dihydroxyacetone kinase
BB341_RS00550	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS00555	COG2124	cytochrome p450
BB341_RS00595	COG1124	(ABC) transporter
BB341_RS00600	COG0444	Belongs to the ABC transporter superfamily
BB341_RS00605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB341_RS00610	COG0601	transmembrane transport
BB341_RS00620	COG1960	acyl-CoA dehydrogenase activity
BB341_RS00625	COG1960	acyl-CoA dehydrogenase activity
BB341_RS00655	COG0517	IMP dehydrogenase activity
BB341_RS00655	COG1125	glycine betaine transport
BB341_RS00660	COG3458	cephalosporin-C deacetylase activity
BB341_RS00675	COG1174	glycine betaine transport
BB341_RS00680	COG1174	glycine betaine transport
BB341_RS00690	COG1309	transcriptional regulator
BB341_RS00710	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BB341_RS00725	COG2124	cytochrome p450
BB341_RS00750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB341_RS00770	COG1024	Enoyl-CoA hydratase
BB341_RS00770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB341_RS00795	COG2124	cytochrome p450
BB341_RS00830	COG0463	Glycosyl transferase, family 2
BB341_RS00845	COG0402	S-adenosylhomocysteine deaminase activity
BB341_RS00865	COG1413	lyase activity
BB341_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS00915	COG2326	polyphosphate kinase activity
BB341_RS00920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB341_RS00965	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BB341_RS00975	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BB341_RS01025	COG0183	Belongs to the thiolase family
BB341_RS01045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB341_RS01050	COG1376	ErfK ybiS ycfS ynhG family protein
BB341_RS01070	COG0535	radical SAM domain protein
BB341_RS01080	COG3424	synthase
BB341_RS01090	COG3959	Transketolase, thiamine diphosphate binding domain
BB341_RS01125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB341_RS01130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BB341_RS01215	COG1131	(ABC) transporter
BB341_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS01265	COG1309	transcriptional regulator
BB341_RS01300	COG3903	Transcriptional regulator
BB341_RS01300	COG3629	intracellular signal transduction
BB341_RS01305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BB341_RS01310	COG1597	lipid kinase activity
BB341_RS01330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB341_RS01330	COG0574	Belongs to the PEP-utilizing enzyme family
BB341_RS01370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BB341_RS01375	COG0477	Major facilitator Superfamily
BB341_RS01395	COG1174	glycine betaine transport
BB341_RS01400	COG1174	glycine betaine transport
BB341_RS01435	COG2957	Belongs to the agmatine deiminase family
BB341_RS01455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BB341_RS01495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BB341_RS01505	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BB341_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB341_RS01530	COG2207	Transcriptional regulator
BB341_RS01535	COG1120	ATPase activity
BB341_RS01540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BB341_RS01555	COG4552	Acetyltransferase involved in intracellular survival and related
BB341_RS01575	COG2197	response regulator
BB341_RS01580	COG0154	amidase activity
BB341_RS01585	COG0477	Major facilitator Superfamily
BB341_RS01590	COG0579	oxidoreductase
BB341_RS01605	COG2755	lipolytic protein G-D-S-L family
BB341_RS01605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BB341_RS01620	COG0745	RESPONSE REGULATOR receiver
BB341_RS01625	COG2205	protein histidine kinase activity
BB341_RS01640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BB341_RS01660	COG0477	Major facilitator Superfamily
BB341_RS01670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB341_RS01675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB341_RS01685	COG1609	Transcriptional regulator
BB341_RS01690	COG0596	Alpha beta hydrolase
BB341_RS01705	COG3572	ergothioneine biosynthetic process
BB341_RS01710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BB341_RS01715	COG0121	glutamine amidotransferase
BB341_RS01720	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BB341_RS01725	COG2182	Extracellular solute-binding protein
BB341_RS01730	COG3360	Dodecin
BB341_RS01740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BB341_RS01745	COG1053	succinate dehydrogenase
BB341_RS01760	COG5001	Diguanylate cyclase
BB341_RS01760	COG3300	MHYT domain
BB341_RS01810	COG3275	phosphorelay sensor kinase activity
BB341_RS01815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BB341_RS01830	COG3279	Response regulator of the LytR AlgR family
BB341_RS01845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BB341_RS01895	COG0297	glycogen (starch) synthase activity
BB341_RS01915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BB341_RS01925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BB341_RS01935	COG3845	ABC transporter
BB341_RS01970	COG2205	protein histidine kinase activity
BB341_RS01975	COG0745	RESPONSE REGULATOR receiver
BB341_RS02005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BB341_RS02025	COG0248	Ppx GppA phosphatase
BB341_RS02070	COG1175	transmembrane transport
BB341_RS02075	COG0395	ABC-type sugar transport system, permease component
BB341_RS02090	COG1051	belongs to the nudix hydrolase family
BB341_RS02095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BB341_RS02105	COG2318	DinB family
BB341_RS02120	COG3251	PFAM MbtH domain protein
BB341_RS02125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BB341_RS02135	COG0667	Aldo Keto reductase
BB341_RS02190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB341_RS02195	COG1129	ABC transporter
BB341_RS02195	COG0842	Transport permease protein
BB341_RS02225	COG2072	flavoprotein involved in K transport
BB341_RS02250	COG1556	Lactate utilization protein
BB341_RS02255	COG1139	Iron-sulfur cluster binding protein
BB341_RS02260	COG0247	lactate metabolic process
BB341_RS02305	COG0438	transferase activity, transferring glycosyl groups
BB341_RS02335	COG0500	methyltransferase
BB341_RS02340	COG4981	capsule polysaccharide biosynthetic process
BB341_RS02395	COG0477	Major facilitator Superfamily
BB341_RS02415	COG2226	methyltransferase
BB341_RS02425	COG0187	DNA topoisomerase II activity
BB341_RS02465	COG0673	inositol 2-dehydrogenase activity
BB341_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS02515	COG2850	peptidyl-arginine hydroxylation
BB341_RS02535	COG0243	molybdopterin cofactor binding
BB341_RS02575	COG3511	phospholipase C
BB341_RS02655	COG1960	acyl-CoA dehydrogenase activity
BB341_RS02700	COG1116	anion transmembrane transporter activity
BB341_RS02710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB341_RS02715	COG4948	Mandelate Racemase Muconate Lactonizing
BB341_RS02720	COG1960	acyl-CoA dehydrogenase activity
BB341_RS02755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BB341_RS02760	COG1309	transcriptional regulator
BB341_RS02770	COG0739	heme binding
BB341_RS02770	COG1196	nuclear chromosome segregation
BB341_RS02770	COG0741	lytic transglycosylase activity
BB341_RS02780	COG2365	Tyrosine phosphatase family
BB341_RS02810	COG1657	PFAM Prenyltransferase squalene oxidase
BB341_RS02820	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BB341_RS02830	COG1562	ergosterol biosynthetic process
BB341_RS02835	COG1134	teichoic acid transport
BB341_RS02850	COG0371	Dehydrogenase
BB341_RS02875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BB341_RS02905	COG2183	response to ionizing radiation
BB341_RS02920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BB341_RS02930	COG2936	dipeptidyl-peptidase activity
BB341_RS02945	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB341_RS02945	COG1024	Enoyl-CoA hydratase
BB341_RS02950	COG0183	Belongs to the thiolase family
BB341_RS02955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB341_RS02960	COG3268	Saccharopine dehydrogenase
BB341_RS02965	COG1515	deoxyribonuclease V activity
BB341_RS02980	COG0488	(ABC) transporter
BB341_RS02985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BB341_RS03025	COG1793	dna ligase
BB341_RS03080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BB341_RS03120	COG3012	SEC-C Motif Domain Protein
BB341_RS03155	COG1609	Transcriptional regulator
BB341_RS03160	COG3345	alpha-galactosidase
BB341_RS03250	COG0475	glutathione-regulated potassium exporter activity
BB341_RS03265	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BB341_RS03270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BB341_RS03275	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BB341_RS03380	COG0673	inositol 2-dehydrogenase activity
BB341_RS03385	COG4213	ABC transporter substrate-binding protein
BB341_RS03390	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB341_RS03395	COG1129	ABC transporter
BB341_RS03400	COG1940	carbohydrate kinase activity
BB341_RS03410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB341_RS03415	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BB341_RS03435	COG1595	DNA-templated transcription, initiation
BB341_RS03445	COG3250	beta-galactosidase activity
BB341_RS03455	COG3250	beta-galactosidase activity
BB341_RS03470	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BB341_RS03475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BB341_RS03485	COG0656	L-ascorbic acid biosynthetic process
BB341_RS03495	COG1793	dna ligase
BB341_RS03540	COG1063	alcohol dehydrogenase
BB341_RS03605	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BB341_RS03610	COG1619	proteins homologs of microcin C7 resistance protein MccF
BB341_RS03620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB341_RS03625	COG2362	D-Aminopeptidase
BB341_RS03680	COG0604	alcohol dehydrogenase
BB341_RS03685	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BB341_RS03685	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BB341_RS03700	COG1960	acyl-CoA dehydrogenase activity
BB341_RS03705	COG0688	phosphatidylethanolamine metabolic process
BB341_RS03715	COG1929	Belongs to the glycerate kinase type-1 family
BB341_RS03730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BB341_RS03735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB341_RS03745	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BB341_RS03760	COG0483	inositol monophosphate 1-phosphatase activity
BB341_RS03765	COG0095	Lipoate-protein ligase
BB341_RS03775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BB341_RS03780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB341_RS03810	COG0405	Gamma-glutamyltransferase
BB341_RS03820	COG0765	amino acid transport
BB341_RS03825	COG0765	amino acid transport
BB341_RS03830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB341_RS03835	COG1126	abc transporter atp-binding protein
BB341_RS03855	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB341_RS03865	COG1940	carbohydrate kinase activity
BB341_RS03885	COG2188	Transcriptional regulator
BB341_RS03890	COG0673	inositol 2-dehydrogenase activity
BB341_RS03900	COG2197	response regulator
BB341_RS03905	COG4585	Histidine kinase
BB341_RS03920	COG4266	Belongs to the allantoicase family
BB341_RS03925	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BB341_RS03930	COG1414	Transcriptional regulator
BB341_RS03945	COG0746	molybdenum cofactor guanylyltransferase activity
BB341_RS03955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BB341_RS03970	COG1288	antiporter activity
BB341_RS03985	COG2233	PERMEase
BB341_RS04000	COG2351	hydroxyisourate hydrolase activity
BB341_RS04025	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS04030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB341_RS04035	COG2197	response regulator
BB341_RS04050	COG3409	Peptidoglycan-binding domain 1 protein
BB341_RS04070	COG1404	Belongs to the peptidase S8 family
BB341_RS04085	COG0243	molybdopterin cofactor binding
BB341_RS04120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB341_RS04135	COG2345	Transcriptional regulator
BB341_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS04155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB341_RS04170	COG2197	response regulator
BB341_RS04175	COG1132	(ABC) transporter
BB341_RS04180	COG1132	(ABC) transporter
BB341_RS04190	COG0515	serine threonine protein kinase
BB341_RS04200	COG1609	Transcriptional regulator
BB341_RS04240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BB341_RS04255	COG3835	regulator
BB341_RS04260	COG1840	ABC-type Fe3 transport system, periplasmic component
BB341_RS04270	COG3842	ATPase activity
BB341_RS04280	COG1802	Transcriptional regulator
BB341_RS04300	COG0028	Belongs to the TPP enzyme family
BB341_RS04330	COG1162	GTPase activity
BB341_RS04355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BB341_RS04385	COG3290	protein histidine kinase activity
BB341_RS04425	COG1960	acyl-CoA dehydrogenase activity
BB341_RS04430	COG3284	Transcriptional regulator
BB341_RS04450	COG0175	sulfate reduction
BB341_RS04455	COG0529	Catalyzes the synthesis of activated sulfate
BB341_RS04475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB341_RS04480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB341_RS04515	COG1175	transmembrane transport
BB341_RS04590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB341_RS04595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BB341_RS04620	COG1764	response to oxidative stress
BB341_RS04625	COG1846	Transcriptional regulator
BB341_RS04645	COG3220	belongs to the UPF0276 family
BB341_RS04665	COG3253	May function as heme-dependent peroxidase
BB341_RS04670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BB341_RS04680	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB341_RS04685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BB341_RS04705	COG0183	Belongs to the thiolase family
BB341_RS04710	COG1024	Enoyl-CoA hydratase
BB341_RS04710	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB341_RS04720	COG0531	amino acid
BB341_RS04725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BB341_RS04730	COG4214	carbohydrate transport
BB341_RS04740	COG4213	ABC transporter substrate-binding protein
BB341_RS04745	COG1940	carbohydrate kinase activity
BB341_RS04750	COG0395	ABC-type sugar transport system, permease component
BB341_RS04755	COG1175	transmembrane transport
BB341_RS04760	COG1653	transport
BB341_RS04770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BB341_RS04775	COG1522	sequence-specific DNA binding
BB341_RS04795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB341_RS04840	COG1024	Enoyl-CoA hydratase
BB341_RS04845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BB341_RS04855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB341_RS04875	COG2040	homocysteine
BB341_RS04895	COG1799	cell septum assembly
BB341_RS04900	COG3903	Transcriptional regulator
BB341_RS04900	COG3629	intracellular signal transduction
BB341_RS04915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BB341_RS04935	COG4689	acetoacetate decarboxylase
BB341_RS04965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BB341_RS04975	COG0745	RESPONSE REGULATOR receiver
BB341_RS04980	COG2205	protein histidine kinase activity
BB341_RS05005	COG0756	dUTP diphosphatase activity
BB341_RS05015	COG4591	ABC-type transport system involved in lipoprotein release permease component
BB341_RS05015	COG1136	(ABC) transporter
BB341_RS05050	COG1136	(ABC) transporter
BB341_RS05050	COG0577	efflux transmembrane transporter activity
BB341_RS05060	COG0569	domain protein
BB341_RS05065	COG0531	amino acid
BB341_RS05070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BB341_RS05080	COG0483	inositol monophosphate 1-phosphatase activity
BB341_RS05085	COG2264	protein methyltransferase activity
BB341_RS05100	COG0494	nUDIX hydrolase
BB341_RS05130	COG0142	geranyltranstransferase activity
BB341_RS05190	COG2409	Drug exporters of the RND superfamily
BB341_RS05210	COG3629	intracellular signal transduction
BB341_RS05210	COG3903	Transcriptional regulator
BB341_RS05220	COG2264	protein methyltransferase activity
BB341_RS05280	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BB341_RS05285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB341_RS05290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BB341_RS05305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB341_RS05315	COG0702	epimerase
BB341_RS05330	COG1435	thymidine kinase activity
BB341_RS05345	COG0045	succinate-CoA ligase (ADP-forming) activity
BB341_RS05345	COG1042	CoA-binding domain protein
BB341_RS05345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB341_RS05350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB341_RS05355	COG1802	Transcriptional regulator
BB341_RS05360	COG0739	heme binding
BB341_RS05360	COG0741	lytic transglycosylase activity
BB341_RS05360	COG1196	nuclear chromosome segregation
BB341_RS05370	COG0612	Peptidase, M16
BB341_RS05375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BB341_RS05385	COG0372	Belongs to the citrate synthase family
BB341_RS05395	COG3290	protein histidine kinase activity
BB341_RS05400	COG4565	transcriptional regulatory protein
BB341_RS05405	COG0187	DNA topoisomerase II activity
BB341_RS05420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB341_RS05425	COG2186	Transcriptional regulator
BB341_RS05430	COG1131	(ABC) transporter
BB341_RS05460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BB341_RS05485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BB341_RS05490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BB341_RS05495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BB341_RS05525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BB341_RS05535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB341_RS05540	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BB341_RS05550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BB341_RS05570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BB341_RS05575	COG2358	TRAP transporter, solute receptor (TAXI family
BB341_RS05580	COG2205	protein histidine kinase activity
BB341_RS05585	COG0745	RESPONSE REGULATOR receiver
BB341_RS05590	COG1126	abc transporter atp-binding protein
BB341_RS05595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB341_RS05600	COG0765	amino acid transport
BB341_RS05605	COG0765	amino acid transport
BB341_RS05610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB341_RS05625	COG2137	regulation of response to DNA damage stimulus
BB341_RS05665	COG1201	RNA secondary structure unwinding
BB341_RS05670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BB341_RS05675	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS05680	COG0783	Belongs to the Dps family
BB341_RS05685	COG1396	sequence-specific DNA binding
BB341_RS05690	COG1546	Belongs to the CinA family
BB341_RS05690	COG1058	Belongs to the CinA family
BB341_RS05700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BB341_RS05710	COG1674	ftsk spoiiie
BB341_RS05720	COG0784	Response regulator, receiver
BB341_RS05720	COG5002	protein histidine kinase activity
BB341_RS05725	COG2770	Histidine kinase
BB341_RS05725	COG2208	phosphoserine phosphatase activity
BB341_RS05750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BB341_RS05755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB341_RS05760	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BB341_RS05780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BB341_RS05785	COG0612	Peptidase, M16
BB341_RS05790	COG1185	polyribonucleotide nucleotidyltransferase activity
BB341_RS05795	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BB341_RS05805	COG1674	ftsk spoiiie
BB341_RS05820	COG1404	Belongs to the peptidase S8 family
BB341_RS05835	COG1404	Belongs to the peptidase S8 family
BB341_RS05840	COG3266	domain, Protein
BB341_RS05860	COG0455	bacterial-type flagellum organization
BB341_RS05865	COG0747	negative chemotaxis
BB341_RS05870	COG0601	transmembrane transport
BB341_RS05875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB341_RS05895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BB341_RS05900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BB341_RS05910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BB341_RS05925	COG0779	Required for maturation of 30S ribosomal subunits
BB341_RS05945	COG0442	prolyl-tRNA aminoacylation
BB341_RS05960	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BB341_RS05965	COG0750	zinc metalloprotease
BB341_RS05970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BB341_RS05985	COG2508	Transcriptional regulator
BB341_RS06015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB341_RS06020	COG1177	transmembrane transport
BB341_RS06025	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB341_RS06030	COG3842	ATPase activity
BB341_RS06055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BB341_RS06070	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS06080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB341_RS06085	COG1136	(ABC) transporter
BB341_RS06100	COG3842	ATPase activity
BB341_RS06115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BB341_RS06120	COG0575	Belongs to the CDS family
BB341_RS06125	COG0233	cytoplasmic translational termination
BB341_RS06130	COG0528	UMP kinase activity
BB341_RS06135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BB341_RS06140	COG0052	Belongs to the universal ribosomal protein uS2 family
BB341_RS06155	COG1191	sigma factor activity
BB341_RS06170	COG0792	nuclease activity
BB341_RS06180	COG0681	Belongs to the peptidase S26 family
BB341_RS06185	COG0681	Belongs to the peptidase S26 family
BB341_RS06190	COG0681	Belongs to the peptidase S26 family
BB341_RS06195	COG0681	Belongs to the peptidase S26 family
BB341_RS06200	COG0335	large ribosomal subunit rRNA binding
BB341_RS06205	COG0336	Belongs to the RNA methyltransferase TrmD family
BB341_RS06210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BB341_RS06215	COG1837	Belongs to the UPF0109 family
BB341_RS06220	COG0228	four-way junction DNA binding
BB341_RS06230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB341_RS06240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BB341_RS06270	COG4552	Acetyltransferase involved in intracellular survival and related
BB341_RS06275	COG0477	Major facilitator Superfamily
BB341_RS06280	COG1196	nuclear chromosome segregation
BB341_RS06290	COG1254	Belongs to the acylphosphatase family
BB341_RS06295	COG2340	Cysteine-rich secretory protein family
BB341_RS06300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BB341_RS06305	COG0571	ribonuclease III activity
BB341_RS06310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BB341_RS06325	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BB341_RS06330	COG0742	ribosomal rna small subunit methyltransferase
BB341_RS06340	COG1461	Dihydroxyacetone kinase
BB341_RS06345	COG0351	phosphomethylpyrimidine kinase
BB341_RS06360	COG1181	Belongs to the D-alanine--D-alanine ligase family
BB341_RS06365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BB341_RS06375	COG1920	GTP binding
BB341_RS06385	COG0776	regulation of translation
BB341_RS06395	COG0066	3-isopropylmalate dehydratase activity
BB341_RS06400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB341_RS06405	COG1414	Transcriptional regulator
BB341_RS06435	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BB341_RS06440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB341_RS06445	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB341_RS06450	COG5002	protein histidine kinase activity
BB341_RS06455	COG2018	Roadblock/LC7 domain
BB341_RS06475	COG2018	Roadblock/LC7 domain
BB341_RS06495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BB341_RS06515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BB341_RS06525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB341_RS06530	COG0477	Major facilitator Superfamily
BB341_RS06540	COG2957	Belongs to the agmatine deiminase family
BB341_RS06545	COG0804	urea catabolic process
BB341_RS06555	COG0832	Belongs to the urease beta subunit family
BB341_RS06555	COG0831	urea catabolic process
BB341_RS06580	COG0300	oxidoreductase activity
BB341_RS06590	COG0604	alcohol dehydrogenase
BB341_RS06590	COG3321	synthase
BB341_RS06605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB341_RS06610	COG0473	3-isopropylmalate dehydrogenase activity
BB341_RS06620	COG1082	Xylose isomerase domain protein TIM barrel
BB341_RS06630	COG1136	(ABC) transporter
BB341_RS06630	COG0577	efflux transmembrane transporter activity
BB341_RS06680	COG0640	Transcriptional regulator
BB341_RS06685	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS06690	COG0506	proline dehydrogenase activity
BB341_RS06695	COG2508	Transcriptional regulator
BB341_RS06695	COG2508	Transcriptional regulator
BB341_RS06700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB341_RS06705	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BB341_RS06710	COG0440	acetolactate synthase activity
BB341_RS06730	COG0667	Aldo Keto reductase
BB341_RS06735	COG2133	pyrroloquinoline quinone binding
BB341_RS06745	COG1672	PFAM Archaeal ATPase
BB341_RS06745	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BB341_RS06755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB341_RS06760	COG2409	Drug exporters of the RND superfamily
BB341_RS06770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BB341_RS06780	COG0154	amidase activity
BB341_RS06785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BB341_RS06795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BB341_RS06805	COG4221	oxidoreductase activity
BB341_RS06810	COG1611	Belongs to the LOG family
BB341_RS06820	COG0482	sulfurtransferase activity
BB341_RS06845	COG2860	membrane
BB341_RS06850	COG4608	Belongs to the ABC transporter superfamily
BB341_RS06855	COG0444	Belongs to the ABC transporter superfamily
BB341_RS06860	COG0601	transmembrane transport
BB341_RS06865	COG0747	negative chemotaxis
BB341_RS06870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB341_RS06890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BB341_RS06895	COG0509	glycine decarboxylation via glycine cleavage system
BB341_RS06900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BB341_RS06905	COG1760	l-serine dehydratase
BB341_RS06910	COG2856	Zn peptidase
BB341_RS07030	COG1024	Enoyl-CoA hydratase
BB341_RS07045	COG1132	(ABC) transporter
BB341_RS07050	COG1132	(ABC) transporter
BB341_RS07060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB341_RS07090	COG2197	response regulator
BB341_RS07095	COG4585	Histidine kinase
BB341_RS07105	COG0058	SHG alpha-glucan phosphorylase activity
BB341_RS07110	COG0366	Alpha amylase catalytic
BB341_RS07115	COG0366	Alpha amylase catalytic
BB341_RS07125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BB341_RS07140	COG1301	dicarboxylic acid transport
BB341_RS07145	COG3290	protein histidine kinase activity
BB341_RS07150	COG4565	transcriptional regulatory protein
BB341_RS07155	COG0181	hydroxymethylbilane synthase activity
BB341_RS07180	COG1175	transmembrane transport
BB341_RS07190	COG0205	6-phosphofructokinase activity
BB341_RS07195	COG0280	phosphate acetyltransferase
BB341_RS07195	COG0857	belongs to the CobB CobQ family
BB341_RS07200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BB341_RS07235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BB341_RS07235	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BB341_RS07280	COG0745	RESPONSE REGULATOR receiver
BB341_RS07295	COG0183	Belongs to the thiolase family
BB341_RS07315	COG1131	(ABC) transporter
BB341_RS07350	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BB341_RS07365	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB341_RS07380	COG4585	Histidine kinase
BB341_RS07385	COG2197	response regulator
BB341_RS07395	COG1088	dTDP-glucose 4,6-dehydratase activity
BB341_RS07415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BB341_RS07445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BB341_RS07455	COG0494	nUDIX hydrolase
BB341_RS07470	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BB341_RS07475	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BB341_RS07480	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BB341_RS07485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BB341_RS07490	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BB341_RS07495	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BB341_RS07500	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BB341_RS07520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BB341_RS07525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BB341_RS07535	COG2890	protein-(glutamine-N5) methyltransferase activity
BB341_RS07540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BB341_RS07545	COG0254	rRNA binding
BB341_RS07550	COG1316	TRANSCRIPTIONal
BB341_RS07565	COG0083	homoserine kinase activity
BB341_RS07570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BB341_RS07575	COG0460	homoserine dehydrogenase
BB341_RS07580	COG0019	diaminopimelate decarboxylase activity
BB341_RS07585	COG0018	arginyl-trna synthetase
BB341_RS07590	COG0745	RESPONSE REGULATOR receiver
BB341_RS07725	COG2367	Beta-lactamase
BB341_RS07730	COG1686	Belongs to the peptidase S11 family
BB341_RS07740	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS07745	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
BB341_RS07750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB341_RS07770	COG2192	nodulation
BB341_RS07780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BB341_RS07790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BB341_RS07800	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
BB341_RS07805	COG0768	penicillin binding
BB341_RS07815	COG0367	asparagine synthase
BB341_RS07820	COG0010	Belongs to the arginase family
BB341_RS07825	COG2175	clavaminate synthase activity
BB341_RS07865	COG0697	spore germination
BB341_RS07870	COG0456	acetyltransferase
BB341_RS07875	COG0747	negative chemotaxis
BB341_RS07885	COG1181	Belongs to the D-alanine--D-alanine ligase family
BB341_RS07890	COG0768	penicillin binding
BB341_RS07895	COG0768	penicillin binding
BB341_RS07900	COG2124	cytochrome p450
BB341_RS07910	COG2205	protein histidine kinase activity
BB341_RS07915	COG0745	RESPONSE REGULATOR receiver
BB341_RS07935	COG2072	flavoprotein involved in K transport
BB341_RS07940	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BB341_RS07945	COG3285	dna ligase
BB341_RS07945	COG1793	dna ligase
BB341_RS07950	COG1793	dna ligase
BB341_RS08000	COG0768	penicillin binding
BB341_RS08030	COG2318	DinB family
BB341_RS08065	COG2205	protein histidine kinase activity
BB341_RS08085	COG1357	PFAM Pentapeptide repeats (8 copies)
BB341_RS08090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BB341_RS08100	COG0745	RESPONSE REGULATOR receiver
BB341_RS08105	COG2205	protein histidine kinase activity
BB341_RS08110	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB341_RS08110	COG0567	Dehydrogenase, E1 component
BB341_RS08120	COG2255	four-way junction helicase activity
BB341_RS08155	COG0604	alcohol dehydrogenase
BB341_RS08175	COG1126	abc transporter atp-binding protein
BB341_RS08180	COG4106	trans-aconitate 2-methyltransferase activity
BB341_RS08200	COG0494	nUDIX hydrolase
BB341_RS08210	COG5640	endopeptidase activity
BB341_RS08230	COG0142	geranyltranstransferase activity
BB341_RS08265	COG1597	lipid kinase activity
BB341_RS08280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BB341_RS08285	COG1472	Belongs to the glycosyl hydrolase 3 family
BB341_RS08290	COG0395	ABC-type sugar transport system, permease component
BB341_RS08295	COG1175	transmembrane transport
BB341_RS08300	COG2182	Extracellular solute-binding protein
BB341_RS08305	COG2188	Transcriptional regulator
BB341_RS08330	COG0242	peptide deformylase activity
BB341_RS08350	COG5662	AntiSigma factor
BB341_RS08355	COG1595	DNA-templated transcription, initiation
BB341_RS08365	COG2135	peptidase activity
BB341_RS08375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BB341_RS08385	COG2076	Multidrug Resistance protein
BB341_RS08395	COG0483	inositol monophosphate 1-phosphatase activity
BB341_RS08405	COG0753	catalase activity
BB341_RS08430	COG1615	UPF0182 protein
BB341_RS08440	COG3480	Lon protease (S16) C-terminal proteolytic domain
BB341_RS08480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BB341_RS08520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB341_RS08575	COG0601	transmembrane transport
BB341_RS08580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB341_RS08585	COG0747	negative chemotaxis
BB341_RS08595	COG0596	Alpha beta hydrolase
BB341_RS08595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB341_RS08625	COG0513	Belongs to the DEAD box helicase family
BB341_RS08645	COG1432	Conserved Protein
BB341_RS08650	COG2095	MarC family integral membrane protein
BB341_RS08670	COG0598	Magnesium transport protein CorA
BB341_RS08705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB341_RS08710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB341_RS08720	COG1595	DNA-templated transcription, initiation
BB341_RS08735	COG1024	Enoyl-CoA hydratase
BB341_RS08740	COG0519	Catalyzes the synthesis of GMP from XMP
BB341_RS08750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BB341_RS08755	COG1611	Belongs to the LOG family
BB341_RS08760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB341_RS08800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BB341_RS08815	COG4608	Belongs to the ABC transporter superfamily
BB341_RS08820	COG0444	Belongs to the ABC transporter superfamily
BB341_RS08825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB341_RS08830	COG0601	transmembrane transport
BB341_RS08845	COG4608	Belongs to the ABC transporter superfamily
BB341_RS08850	COG0444	Belongs to the ABC transporter superfamily
BB341_RS08860	COG4166	transmembrane transport
BB341_RS08865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB341_RS08870	COG1217	gtp-binding protein TYPA
BB341_RS08890	COG1053	succinate dehydrogenase
BB341_RS08940	COG0012	GTP binding
BB341_RS08955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BB341_RS08960	COG0531	amino acid
BB341_RS08965	COG1570	exodeoxyribonuclease VII activity
BB341_RS08970	COG1722	exodeoxyribonuclease VII activity
BB341_RS08975	COG0778	Nitroreductase
BB341_RS09000	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BB341_RS09000	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BB341_RS09010	COG0114	fumarate hydratase activity
BB341_RS09030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB341_RS09050	COG1136	(ABC) transporter
BB341_RS09065	COG0450	alkyl hydroperoxide reductase
BB341_RS09070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB341_RS09085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BB341_RS09090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BB341_RS09095	COG0667	Aldo Keto reductase
BB341_RS09120	COG2885	chlorophyll binding
BB341_RS09140	COG2197	response regulator
BB341_RS09145	COG4585	Histidine kinase
BB341_RS09175	COG2894	cell division
BB341_RS09200	COG2610	gluconate transmembrane transporter activity
BB341_RS09205	COG0251	oxidation-reduction process
BB341_RS09210	COG1414	Transcriptional regulator
BB341_RS09225	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BB341_RS09285	COG0492	ferredoxin-NADP+ reductase activity
BB341_RS09310	COG0438	transferase activity, transferring glycosyl groups
BB341_RS09320	COG0728	peptidoglycan biosynthetic process
BB341_RS09330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BB341_RS09335	COG0438	transferase activity, transferring glycosyl groups
BB341_RS09375	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BB341_RS09385	COG1309	transcriptional regulator
BB341_RS09390	COG1331	Highly conserved protein containing a thioredoxin domain
BB341_RS09420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BB341_RS09430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB341_RS09440	COG2188	Transcriptional regulator
BB341_RS09460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB341_RS09500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB341_RS09510	COG1064	alcohol dehydrogenase
BB341_RS09525	COG2986	histidine ammonia-lyase
BB341_RS09535	COG1024	Enoyl-CoA hydratase
BB341_RS09550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BB341_RS09560	COG0424	maF-like protein
BB341_RS09565	COG4770	biotin carboxylase activity
BB341_RS09595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BB341_RS09625	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS09630	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS09645	COG1595	DNA-templated transcription, initiation
BB341_RS09650	COG0745	RESPONSE REGULATOR receiver
BB341_RS09655	COG2205	protein histidine kinase activity
BB341_RS09680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BB341_RS09695	COG0583	DNA-binding transcription factor activity
BB341_RS09700	COG2814	Major facilitator Superfamily
BB341_RS09735	COG1079	Belongs to the binding-protein-dependent transport system permease family
BB341_RS09740	COG4603	Belongs to the binding-protein-dependent transport system permease family
BB341_RS09745	COG3845	ABC transporter
BB341_RS09750	COG1744	ABC transporter substrate-binding protein PnrA-like
BB341_RS09755	COG1473	amidohydrolase
BB341_RS09755	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BB341_RS09765	COG2089	acid synthase
BB341_RS09770	COG1083	cytidylyl-transferase
BB341_RS09780	COG1216	Glycosyl transferase, family 2
BB341_RS09795	COG0517	IMP dehydrogenase activity
BB341_RS09795	COG0516	GMP reductase activity
BB341_RS09810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BB341_RS09810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BB341_RS09825	COG1595	DNA-templated transcription, initiation
BB341_RS09835	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BB341_RS09840	COG2009	succinate dehydrogenase
BB341_RS09850	COG1053	succinate dehydrogenase
BB341_RS09855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BB341_RS09865	COG1408	metallophosphoesterase
BB341_RS09875	COG1686	Belongs to the peptidase S11 family
BB341_RS09880	COG1295	ribonuclease BN
BB341_RS09885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BB341_RS09910	COG0180	Tryptophanyl-tRNA synthetase
BB341_RS09915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BB341_RS09920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB341_RS09925	COG0754	glutathionylspermidine amidase activity
BB341_RS09935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB341_RS09970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB341_RS09980	COG0039	L-malate dehydrogenase activity
BB341_RS09995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BB341_RS10010	COG0138	bifunctional purine biosynthesis protein purh
BB341_RS10040	COG0045	succinate-CoA ligase (ADP-forming) activity
BB341_RS10045	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BB341_RS10055	COG0714	Associated with various cellular activities
BB341_RS10070	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BB341_RS10070	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BB341_RS10080	COG0739	heme binding
BB341_RS10100	COG2197	response regulator
BB341_RS10125	COG0519	Catalyzes the synthesis of GMP from XMP
BB341_RS10125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BB341_RS10145	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS10165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BB341_RS10175	COG0516	GMP reductase activity
BB341_RS10185	COG1595	DNA-templated transcription, initiation
BB341_RS10190	COG2197	response regulator
BB341_RS10200	COG0583	DNA-binding transcription factor activity
BB341_RS10215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB341_RS10220	COG0459	protein refolding
BB341_RS10225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BB341_RS10230	COG0726	polysaccharide deacetylase
BB341_RS10240	COG4941	Belongs to the sigma-70 factor family
BB341_RS10265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BB341_RS10290	COG0802	atpase or kinase
BB341_RS10300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB341_RS10320	COG0736	holo-[acyl-carrier-protein] synthase activity
BB341_RS10325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BB341_RS10330	COG1072	(Pantothenic acid kinase))
BB341_RS10335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BB341_RS10340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BB341_RS10345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BB341_RS10350	COG0488	(ABC) transporter
BB341_RS10360	COG0101	tRNA pseudouridine synthase activity
BB341_RS10365	COG0203	ribosomal protein L17
BB341_RS10370	COG0202	RNA polymerase activity
BB341_RS10375	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BB341_RS10380	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BB341_RS10385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BB341_RS10390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BB341_RS10400	COG0563	adenylate kinase activity
BB341_RS10410	COG0200	Binds to the 23S rRNA
BB341_RS10415	COG1841	ribosomal large subunit assembly
BB341_RS10420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BB341_RS10425	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BB341_RS10430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BB341_RS10435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BB341_RS10440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BB341_RS10445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BB341_RS10450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BB341_RS10455	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BB341_RS10460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BB341_RS10465	COG0255	Belongs to the universal ribosomal protein uL29 family
BB341_RS10470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BB341_RS10475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BB341_RS10480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BB341_RS10485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BB341_RS10490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BB341_RS10495	COG0089	rRNA binding
BB341_RS10500	COG0088	Forms part of the polypeptide exit tunnel
BB341_RS10505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BB341_RS10510	COG0051	transcription antitermination factor activity, RNA binding
BB341_RS10520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BB341_RS10525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BB341_RS10530	COG0049	tRNA binding
BB341_RS10535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BB341_RS10540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BB341_RS10545	COG0085	RNA polymerase activity
BB341_RS10550	COG0222	ribosome binding
BB341_RS10555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BB341_RS10560	COG0081	regulation of translation
BB341_RS10565	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BB341_RS10575	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB341_RS10585	COG0436	Aminotransferase
BB341_RS10590	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BB341_RS10595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BB341_RS10605	COG2030	dehydratase
BB341_RS10610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BB341_RS10630	COG0702	epimerase
BB341_RS10645	COG1666	GTP binding
BB341_RS10650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB341_RS10660	COG3304	Inner membrane component domain
BB341_RS10665	COG0501	Belongs to the peptidase M48B family
BB341_RS10670	COG1007	ATP synthesis coupled electron transport
BB341_RS10685	COG0713	ATP synthesis coupled electron transport
BB341_RS10690	COG0839	Belongs to the complex I subunit 6 family
BB341_RS10695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB341_RS10700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BB341_RS10705	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB341_RS10710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB341_RS10715	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB341_RS10720	COG4585	Histidine kinase
BB341_RS10735	COG0674	pyruvate-flavodoxin oxidoreductase activity
BB341_RS10735	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BB341_RS10740	COG1013	pyruvate-flavodoxin oxidoreductase activity
BB341_RS10765	COG1733	regulation of RNA biosynthetic process
BB341_RS10780	COG2234	aminopeptidase activity
BB341_RS10780	COG4935	Belongs to the peptidase S8 family
BB341_RS10805	COG0142	geranyltranstransferase activity
BB341_RS10810	COG2936	dipeptidyl-peptidase activity
BB341_RS10815	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB341_RS10820	COG1007	ATP synthesis coupled electron transport
BB341_RS10830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BB341_RS10835	COG0713	ATP synthesis coupled electron transport
BB341_RS10840	COG0839	Belongs to the complex I subunit 6 family
BB341_RS10845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB341_RS10850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BB341_RS10855	COG1034	ATP synthesis coupled electron transport
BB341_RS10860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BB341_RS10870	COG0649	NAD binding
BB341_RS10875	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB341_RS10880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB341_RS10910	COG2226	methyltransferase
BB341_RS10920	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BB341_RS10925	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BB341_RS10930	COG1278	Cold shock
BB341_RS10935	COG1823	symporter activity
BB341_RS10950	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BB341_RS10960	COG0163	prenyltransferase activity
BB341_RS10965	COG0109	protoheme IX farnesyltransferase activity
BB341_RS10970	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BB341_RS10980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BB341_RS10985	COG1333	cytochrome c biogenesis protein
BB341_RS10990	COG0785	Cytochrome C biogenesis protein
BB341_RS10995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB341_RS11000	COG0406	alpha-ribazole phosphatase activity
BB341_RS11005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BB341_RS11020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB341_RS11030	COG1742	UPF0060 membrane protein
BB341_RS11045	COG0402	S-adenosylhomocysteine deaminase activity
BB341_RS11050	COG1690	Belongs to the RtcB family
BB341_RS11090	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BB341_RS11095	COG0626	cystathionine gamma-synthase activity
BB341_RS11110	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BB341_RS11115	COG0018	arginyl-trna synthetase
BB341_RS11135	COG0113	porphobilinogen synthase activity
BB341_RS11150	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BB341_RS11240	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BB341_RS11245	COG0596	Alpha beta hydrolase
BB341_RS11270	COG1136	(ABC) transporter
BB341_RS11345	COG1725	Transcriptional regulator
BB341_RS11360	COG1309	transcriptional regulator
BB341_RS11380	COG0702	epimerase
BB341_RS11390	COG1960	acyl-CoA dehydrogenase activity
BB341_RS11415	COG0259	pyridoxamine-phosphate oxidase activity
BB341_RS11430	COG2072	flavoprotein involved in K transport
BB341_RS11440	COG1024	Enoyl-CoA hydratase
BB341_RS11450	COG0456	acetyltransferase
BB341_RS11455	COG2814	Major facilitator Superfamily
BB341_RS11455	COG0477	Major facilitator Superfamily
BB341_RS11460	COG1181	Belongs to the D-alanine--D-alanine ligase family
BB341_RS11475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BB341_RS11480	COG2271	Major facilitator Superfamily
BB341_RS11485	COG1917	Cupin 2, conserved barrel domain protein
BB341_RS11485	COG4977	sequence-specific DNA binding
BB341_RS11495	COG1960	acyl-CoA dehydrogenase activity
BB341_RS11500	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS11515	COG1960	acyl-CoA dehydrogenase activity
BB341_RS11520	COG1960	acyl-CoA dehydrogenase activity
BB341_RS11530	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS11535	COG3397	chitin binding
BB341_RS11605	COG2945	thiolester hydrolase activity
BB341_RS11605	COG0596	Alpha beta hydrolase
BB341_RS11615	COG4821	SIS domain
BB341_RS11625	COG0259	pyridoxamine-phosphate oxidase activity
BB341_RS11645	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS11660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BB341_RS11720	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS11765	COG0726	polysaccharide deacetylase
BB341_RS11795	COG0577	efflux transmembrane transporter activity
BB341_RS11800	COG0577	efflux transmembrane transporter activity
BB341_RS11800	COG1136	(ABC) transporter
BB341_RS11835	COG0583	DNA-binding transcription factor activity
BB341_RS11850	COG2205	protein histidine kinase activity
BB341_RS11855	COG0745	RESPONSE REGULATOR receiver
BB341_RS11870	COG0247	lactate metabolic process
BB341_RS11870	COG0277	FAD linked oxidase domain protein
BB341_RS11880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BB341_RS11920	COG0463	Glycosyl transferase, family 2
BB341_RS11930	COG3903	Transcriptional regulator
BB341_RS11930	COG3629	intracellular signal transduction
BB341_RS11945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB341_RS11985	COG1122	ATPase activity
BB341_RS12005	COG0667	Aldo Keto reductase
BB341_RS12040	COG2252	PERMEase
BB341_RS12050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB341_RS12070	COG2814	Major facilitator Superfamily
BB341_RS12080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BB341_RS12085	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BB341_RS12090	COG1278	Cold shock
BB341_RS12125	COG1061	Type III restriction enzyme res subunit
BB341_RS12135	COG3973	AAA domain
BB341_RS12150	COG1595	DNA-templated transcription, initiation
BB341_RS12220	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BB341_RS12225	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BB341_RS12235	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS12240	COG1605	Chorismate mutase
BB341_RS12260	COG2197	response regulator
BB341_RS12280	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BB341_RS12305	COG0191	fructose-bisphosphate aldolase activity
BB341_RS12310	COG1105	Belongs to the carbohydrate kinase PfkB family
BB341_RS12325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BB341_RS12330	COG2182	Extracellular solute-binding protein
BB341_RS12355	COG0463	Glycosyl transferase, family 2
BB341_RS12420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB341_RS12440	COG3842	ATPase activity
BB341_RS12450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BB341_RS12460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB341_RS12465	COG0215	cysteine-tRNA ligase activity
BB341_RS12475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BB341_RS12480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BB341_RS12485	COG1329	Transcriptional regulator
BB341_RS12500	COG5002	protein histidine kinase activity
BB341_RS12510	COG0588	phosphoglycerate mutase activity
BB341_RS12515	COG2211	Major facilitator Superfamily
BB341_RS12540	COG0438	transferase activity, transferring glycosyl groups
BB341_RS12600	COG1490	D-aminoacyl-tRNA deacylase activity
BB341_RS12615	COG3485	protocatechuate 3,4-dioxygenase
BB341_RS12640	COG1309	transcriptional regulator
BB341_RS12660	COG0745	RESPONSE REGULATOR receiver
BB341_RS12665	COG1609	Transcriptional regulator
BB341_RS12680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB341_RS12700	COG2188	Transcriptional regulator
BB341_RS12710	COG4085	toxin activity
BB341_RS12710	COG1525	nuclease
BB341_RS12710	COG0737	Belongs to the 5'-nucleotidase family
BB341_RS12730	COG0456	acetyltransferase
BB341_RS12735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BB341_RS12745	COG0494	nUDIX hydrolase
BB341_RS12745	COG0406	alpha-ribazole phosphatase activity
BB341_RS12770	COG0306	phosphate transporter
BB341_RS12780	COG1937	Protein conserved in bacteria
BB341_RS12795	COG0671	phosphoesterase, PA-phosphatase related
BB341_RS12800	COG0739	heme binding
BB341_RS12800	COG0741	lytic transglycosylase activity
BB341_RS12800	COG1196	nuclear chromosome segregation
BB341_RS12895	COG0579	oxidoreductase
BB341_RS12900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BB341_RS12910	COG0739	heme binding
BB341_RS12910	COG0741	lytic transglycosylase activity
BB341_RS12910	COG1196	nuclear chromosome segregation
BB341_RS12965	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB341_RS12975	COG0513	Belongs to the DEAD box helicase family
BB341_RS12985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BB341_RS12990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BB341_RS13025	COG0785	Cytochrome C biogenesis protein
BB341_RS13030	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BB341_RS13030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BB341_RS13040	COG1643	Atp-dependent helicase
BB341_RS13070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BB341_RS13100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BB341_RS13105	COG0047	phosphoribosylformylglycinamidine synthase activity
BB341_RS13110	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BB341_RS13145	COG2197	response regulator
BB341_RS13155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BB341_RS13170	COG0151	Belongs to the GarS family
BB341_RS13200	COG0017	Asparaginyl-tRNA synthetase
BB341_RS13205	COG1051	belongs to the nudix hydrolase family
BB341_RS13215	COG0105	UTP biosynthetic process
BB341_RS13250	COG2826	transposase and inactivated derivatives, IS30 family
BB341_RS13280	COG3903	Transcriptional regulator
BB341_RS13280	COG3629	intracellular signal transduction
BB341_RS13345	COG0477	Major facilitator Superfamily
BB341_RS13375	COG2234	aminopeptidase activity
BB341_RS13380	COG0433	COG0433 Predicted ATPase
BB341_RS13395	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BB341_RS13435	COG1191	sigma factor activity
BB341_RS13440	COG1191	sigma factor activity
BB341_RS13490	COG2304	oxidoreductase activity
BB341_RS13495	COG2205	protein histidine kinase activity
BB341_RS13500	COG0745	RESPONSE REGULATOR receiver
BB341_RS13505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB341_RS13525	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BB341_RS13550	COG1960	acyl-CoA dehydrogenase activity
BB341_RS13560	COG1362	aminopeptidase activity
BB341_RS13580	COG2271	Major facilitator Superfamily
BB341_RS13595	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB341_RS13600	COG0022	dehydrogenase e1 component
BB341_RS13625	COG0515	serine threonine protein kinase
BB341_RS13630	COG0515	serine threonine protein kinase
BB341_RS13645	COG4591	ABC-type transport system involved in lipoprotein release permease component
BB341_RS13645	COG1136	(ABC) transporter
BB341_RS13675	COG0303	'Molybdopterin
BB341_RS13700	COG1522	sequence-specific DNA binding
BB341_RS13705	COG1309	transcriptional regulator
BB341_RS13710	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB341_RS13735	COG3396	Phenylacetate-CoA oxygenase
BB341_RS13740	COG3460	Phenylacetate-CoA oxygenase
BB341_RS13745	COG3396	Phenylacetate-CoA oxygenase
BB341_RS13750	COG2151	metal-sulfur cluster biosynthetic enzyme
BB341_RS13755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB341_RS13760	COG1960	acyl-CoA dehydrogenase activity
BB341_RS13765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BB341_RS13780	COG2197	response regulator
BB341_RS13785	COG4585	Histidine kinase
BB341_RS13810	COG1136	(ABC) transporter
BB341_RS13810	COG0577	efflux transmembrane transporter activity
BB341_RS13815	COG0577	efflux transmembrane transporter activity
BB341_RS13815	COG1136	(ABC) transporter
BB341_RS13825	COG1716	ATPase activity
BB341_RS13830	COG1716	ATPase activity
BB341_RS13845	COG0768	penicillin binding
BB341_RS13850	COG0515	serine threonine protein kinase
BB341_RS13855	COG3764	Sortase (surface protein transpeptidase)
BB341_RS13860	COG3764	Sortase (surface protein transpeptidase)
BB341_RS13875	COG3764	Sortase (surface protein transpeptidase)
BB341_RS13890	COG0457	Tetratricopeptide repeat
BB341_RS13890	COG0705	Rhomboid family
BB341_RS13920	COG1446	asparaginase
BB341_RS13925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB341_RS13930	COG1280	lysine exporter protein (LysE YggA)
BB341_RS13950	COG0667	Aldo Keto reductase
BB341_RS13955	COG2175	clavaminate synthase activity
BB341_RS13960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB341_RS13965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB341_RS13970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB341_RS13985	COG0515	serine threonine protein kinase
BB341_RS14000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BB341_RS14010	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
BB341_RS14015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BB341_RS14020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BB341_RS14025	COG0592	DNA-directed DNA polymerase activity
BB341_RS14040	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BB341_RS14045	COG0706	membrane insertase activity
BB341_RS14055	COG0357	Ribosomal RNA small subunit methyltransferase G
BB341_RS14060	COG1192	Involved in chromosome partitioning
BB341_RS14075	COG3118	belongs to the thioredoxin family
BB341_RS14080	COG0492	ferredoxin-NADP+ reductase activity
BB341_RS14090	COG1595	DNA-templated transcription, initiation
BB341_RS14095	COG0515	serine threonine protein kinase
BB341_RS14095	COG2815	serine threonine protein kinase
BB341_RS14110	COG0617	tRNA 3'-terminal CCA addition
BB341_RS14130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB341_RS14155	COG0360	Binds together with S18 to 16S ribosomal RNA
BB341_RS14160	COG0629	single-stranded DNA binding
BB341_RS14165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BB341_RS14170	COG0359	binds to the 23S rRNA
BB341_RS14180	COG0305	Participates in initiation and elongation during chromosome replication
BB341_RS14215	COG0626	cystathionine gamma-synthase activity
BB341_RS14220	COG1950	PFAM Membrane protein of
BB341_RS14225	COG0662	Cupin 2, conserved barrel domain protein
BB341_RS14245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BB341_RS14260	COG1609	Transcriptional regulator
BB341_RS14265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB341_RS14270	COG1271	oxidase subunit
BB341_RS14275	COG1294	oxidase, subunit
BB341_RS14280	COG4988	ABC transporter
BB341_RS14290	COG0561	phosphatase activity
BB341_RS14300	COG1131	(ABC) transporter
BB341_RS14335	COG0561	phosphatase activity
BB341_RS14340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BB341_RS14345	COG0077	Prephenate dehydratase
BB341_RS14350	COG2837	iron assimilation
BB341_RS14365	COG1999	signal sequence binding
BB341_RS14385	COG0006	proline dipeptidase activity
BB341_RS14415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB341_RS14445	COG0587	DNA-directed DNA polymerase activity
BB341_RS14450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BB341_RS14475	COG1595	DNA-templated transcription, initiation
BB341_RS14480	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS14485	COG0784	Response regulator, receiver
BB341_RS14515	COG0745	RESPONSE REGULATOR receiver
BB341_RS14520	COG0477	Major facilitator Superfamily
BB341_RS14540	COG0431	NADPH-dependent FMN reductase
BB341_RS14565	COG1672	PFAM Archaeal ATPase
BB341_RS14565	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BB341_RS14570	COG0431	NADPH-dependent FMN reductase
BB341_RS14600	COG0598	Magnesium transport protein CorA
BB341_RS14605	COG3345	alpha-galactosidase
BB341_RS14680	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BB341_RS14690	COG2226	methyltransferase
BB341_RS14695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BB341_RS14735	COG2826	transposase and inactivated derivatives, IS30 family
BB341_RS14830	COG1857	crispr-associated protein
BB341_RS14850	COG0436	Aminotransferase
BB341_RS14860	COG2197	response regulator
BB341_RS14870	COG0577	efflux transmembrane transporter activity
BB341_RS14935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BB341_RS14960	COG3903	Transcriptional regulator
BB341_RS14960	COG3629	intracellular signal transduction
BB341_RS15005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BB341_RS15015	COG0534	Mate efflux family protein
BB341_RS15020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BB341_RS15025	COG0019	diaminopimelate decarboxylase activity
BB341_RS15040	COG4166	transmembrane transport
BB341_RS15045	COG0601	transmembrane transport
BB341_RS15050	COG4171	peptide transport system, permease
BB341_RS15065	COG2197	response regulator
BB341_RS15070	COG4585	Histidine kinase
BB341_RS15075	COG2409	Drug exporters of the RND superfamily
BB341_RS15100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB341_RS15110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB341_RS15115	COG0588	phosphoglycerate mutase activity
BB341_RS15165	COG0717	Belongs to the dCTP deaminase family
BB341_RS15180	COG0247	lactate metabolic process
BB341_RS15180	COG2181	nitrate reductase activity
BB341_RS15185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BB341_RS15190	COG0443	Heat shock 70 kDa protein
BB341_RS15195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BB341_RS15200	COG0484	heat shock protein binding
BB341_RS15205	COG0789	Transcriptional regulator
BB341_RS15225	COG0542	response to heat
BB341_RS15250	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BB341_RS15265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BB341_RS15270	COG0191	fructose-bisphosphate aldolase activity
BB341_RS15275	COG0477	Major facilitator Superfamily
BB341_RS15310	COG4585	Histidine kinase
BB341_RS15320	COG2124	cytochrome p450
BB341_RS15350	COG0463	Glycosyl transferase, family 2
BB341_RS15355	COG1802	Transcriptional regulator
BB341_RS15370	COG4249	Peptidase C14 caspase catalytic subunit p20
BB341_RS15370	COG2319	Wd-40 repeat
BB341_RS15375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB341_RS15410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BB341_RS15425	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BB341_RS15430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BB341_RS15445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BB341_RS15450	COG1595	DNA-templated transcription, initiation
BB341_RS15475	COG2124	cytochrome p450
BB341_RS15490	COG2091	lysine biosynthetic process via aminoadipic acid
BB341_RS15505	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BB341_RS15535	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BB341_RS15615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BB341_RS15635	COG1408	metallophosphoesterase
BB341_RS15640	COG1610	YqeY-like protein
BB341_RS15645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB341_RS15655	COG0003	Pfam Anion-transporting ATPase
BB341_RS15680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BB341_RS15710	COG2267	carboxylic ester hydrolase activity
BB341_RS15720	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BB341_RS15725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB341_RS15730	COG0659	secondary active sulfate transmembrane transporter activity
BB341_RS15780	COG1111	helicase
BB341_RS15780	COG1205	dead DEAH box helicase
BB341_RS15785	COG1366	Belongs to the anti-sigma-factor antagonist family
BB341_RS15790	COG2172	sigma factor antagonist activity
BB341_RS15795	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BB341_RS15805	COG2890	protein-(glutamine-N5) methyltransferase activity
BB341_RS15815	COG1754	DNA topoisomerase type I activity
BB341_RS15815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BB341_RS15825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BB341_RS15830	COG0470	DNA polymerase III
BB341_RS15840	COG0477	Major facilitator Superfamily
BB341_RS15880	COG1061	Type III restriction enzyme res subunit
BB341_RS15925	COG0791	NLP P60 protein
BB341_RS15995	COG0305	Participates in initiation and elongation during chromosome replication
BB341_RS16140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BB341_RS16245	COG1132	(ABC) transporter
BB341_RS16250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BB341_RS16250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BB341_RS16255	COG0110	maltose O-acetyltransferase activity
BB341_RS16295	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS16300	COG2318	DinB family
BB341_RS16315	COG0076	glutamate decarboxylase activity
BB341_RS16330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BB341_RS16335	COG2027	D-alanyl-D-alanine carboxypeptidase
BB341_RS16345	COG0037	tRNA processing
BB341_RS16360	COG0302	gtp cyclohydrolase
BB341_RS16375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BB341_RS16400	COG1174	glycine betaine transport
BB341_RS16415	COG0649	NAD binding
BB341_RS16430	COG2197	response regulator
BB341_RS16445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BB341_RS16450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BB341_RS16460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BB341_RS16480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BB341_RS16495	COG2027	D-alanyl-D-alanine carboxypeptidase
BB341_RS16505	COG0739	heme binding
BB341_RS16510	COG2205	protein histidine kinase activity
BB341_RS16515	COG0745	RESPONSE REGULATOR receiver
BB341_RS16525	COG1595	DNA-templated transcription, initiation
BB341_RS16530	COG1194	a g-specific adenine glycosylase
BB341_RS16535	COG0671	phosphoesterase, PA-phosphatase related
BB341_RS16545	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BB341_RS16565	COG0248	Ppx GppA phosphatase
BB341_RS16570	COG1082	Xylose isomerase domain protein TIM barrel
BB341_RS16575	COG0129	dihydroxy-acid dehydratase activity
BB341_RS16595	COG2226	methyltransferase
BB341_RS16600	COG1595	DNA-templated transcription, initiation
BB341_RS16605	COG1252	NADH dehydrogenase
BB341_RS16610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BB341_RS16615	COG0180	Tryptophanyl-tRNA synthetase
BB341_RS16640	COG0123	including yeast histone deacetylase and acetoin utilization protein
BB341_RS16665	COG1595	DNA-templated transcription, initiation
BB341_RS16680	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BB341_RS16685	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BB341_RS16690	COG0181	hydroxymethylbilane synthase activity
BB341_RS16695	COG1648	precorrin-2 dehydrogenase activity
BB341_RS16695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BB341_RS16720	COG1846	Transcriptional regulator
BB341_RS16725	COG3384	dioxygenase
BB341_RS16745	COG0477	Major facilitator Superfamily
BB341_RS16755	COG3191	aminopeptidase activity
BB341_RS16770	COG1970	mechanosensitive ion channel activity
BB341_RS16780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BB341_RS16805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BB341_RS16810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BB341_RS16820	COG0315	cyclic pyranopterin monophosphate synthase activity
BB341_RS16825	COG0521	Mo-molybdopterin cofactor biosynthetic process
BB341_RS16825	COG0315	cyclic pyranopterin monophosphate synthase activity
BB341_RS16830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB341_RS16875	COG2072	flavoprotein involved in K transport
BB341_RS16880	COG2267	carboxylic ester hydrolase activity
BB341_RS16885	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS16890	COG4946	Tricorn protease homolog
BB341_RS16890	COG0793	Belongs to the peptidase S41A family
BB341_RS16900	COG2409	Drug exporters of the RND superfamily
BB341_RS16910	COG0310	cobalt ion transport
BB341_RS16920	COG1122	ATPase activity
BB341_RS16925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BB341_RS16965	COG0124	histidyl-tRNA synthetase
BB341_RS16990	COG3409	Peptidoglycan-binding domain 1 protein
BB341_RS16995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BB341_RS17015	COG0442	prolyl-tRNA aminoacylation
BB341_RS17045	COG0084	hydrolase, TatD family'
BB341_RS17055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BB341_RS17060	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BB341_RS17085	COG0488	(ABC) transporter
BB341_RS17115	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BB341_RS17120	COG2197	response regulator
BB341_RS17130	COG4106	trans-aconitate 2-methyltransferase activity
BB341_RS17135	COG1309	transcriptional regulator
BB341_RS17145	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BB341_RS17155	COG0193	aminoacyl-tRNA hydrolase activity
BB341_RS17160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BB341_RS17165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BB341_RS17170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BB341_RS17180	COG4585	Histidine kinase
BB341_RS17210	COG0477	Major facilitator Superfamily
BB341_RS17225	COG1136	(ABC) transporter
BB341_RS17230	COG0577	efflux transmembrane transporter activity
BB341_RS17235	COG1595	DNA-templated transcription, initiation
BB341_RS17260	COG2815	serine threonine protein kinase
BB341_RS17260	COG0515	serine threonine protein kinase
BB341_RS17290	COG1652	LysM domain
BB341_RS17300	COG0148	phosphopyruvate hydratase activity
BB341_RS17320	COG1252	NADH dehydrogenase
BB341_RS17325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BB341_RS17330	COG0577	efflux transmembrane transporter activity
BB341_RS17330	COG1136	(ABC) transporter
BB341_RS17335	COG0577	efflux transmembrane transporter activity
BB341_RS17335	COG1136	(ABC) transporter
BB341_RS17365	COG0183	Belongs to the thiolase family
BB341_RS17370	COG2755	lipolytic protein G-D-S-L family
BB341_RS17385	COG1737	Transcriptional regulator
BB341_RS17445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BB341_RS17475	COG1228	amidohydrolase
BB341_RS17505	COG1191	sigma factor activity
BB341_RS17530	COG3104	oligopeptide transport
BB341_RS17535	COG0745	RESPONSE REGULATOR receiver
BB341_RS17540	COG2205	protein histidine kinase activity
BB341_RS17575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BB341_RS17650	COG1309	transcriptional regulator
BB341_RS17655	COG0596	Alpha beta hydrolase
BB341_RS17660	COG1316	TRANSCRIPTIONal
BB341_RS17665	COG1607	acyl-coa hydrolase
BB341_RS17670	COG1316	TRANSCRIPTIONal
BB341_RS17690	COG1316	TRANSCRIPTIONal
BB341_RS17715	COG0778	Nitroreductase
BB341_RS17715	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BB341_RS17720	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BB341_RS17755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BB341_RS17760	COG2835	tetraacyldisaccharide 4'-kinase activity
BB341_RS17770	COG1482	cell wall glycoprotein biosynthetic process
BB341_RS17780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BB341_RS17805	COG2826	transposase and inactivated derivatives, IS30 family
BB341_RS17815	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BB341_RS17820	COG0745	RESPONSE REGULATOR receiver
BB341_RS17825	COG5000	phosphorelay sensor kinase activity
BB341_RS17825	COG5002	protein histidine kinase activity
BB341_RS17830	COG0823	Involved in the tonB-independent uptake of proteins
BB341_RS17840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BB341_RS17845	COG2197	response regulator
BB341_RS17850	COG3214	Protein conserved in bacteria
BB341_RS17860	COG0653	protein targeting
BB341_RS17885	COG2902	Dehydrogenase
BB341_RS17895	COG0395	ABC-type sugar transport system, permease component
BB341_RS17900	COG1175	transmembrane transport
BB341_RS17915	COG0515	serine threonine protein kinase
BB341_RS17920	COG0515	serine threonine protein kinase
BB341_RS17925	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BB341_RS17935	COG2884	Cell division ATP-binding protein ftsE
BB341_RS17945	COG0793	Belongs to the peptidase S41A family
BB341_RS17950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BB341_RS17965	COG0583	DNA-binding transcription factor activity
BB341_RS17990	COG3973	AAA domain
BB341_RS18000	COG0776	regulation of translation
BB341_RS18005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB341_RS18010	COG1678	Uncharacterized ACR, COG1678
BB341_RS18025	COG1175	transmembrane transport
BB341_RS18030	COG0395	ABC-type sugar transport system, permease component
BB341_RS18035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BB341_RS18075	COG3654	unkown
BB341_RS18100	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BB341_RS18105	COG0745	RESPONSE REGULATOR receiver
BB341_RS18110	COG5002	protein histidine kinase activity
BB341_RS18130	COG0277	FAD linked oxidase domain protein
BB341_RS18170	COG1335	isochorismatase
BB341_RS18180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BB341_RS18190	COG1113	amino acid transport
BB341_RS18200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BB341_RS18205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB341_RS18210	COG1120	ATPase activity
BB341_RS18225	COG1234	tRNA 3'-trailer cleavage
BB341_RS18230	COG1263	PTS System
BB341_RS18235	COG1263	PTS System
BB341_RS18240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB341_RS18245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BB341_RS18255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BB341_RS18285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BB341_RS18295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB341_RS18310	COG1131	(ABC) transporter
BB341_RS18320	COG2733	membrane
BB341_RS18350	COG0706	membrane insertase activity
BB341_RS18360	COG0673	inositol 2-dehydrogenase activity
BB341_RS18435	COG1126	abc transporter atp-binding protein
BB341_RS18440	COG0765	amino acid transport
BB341_RS18445	COG0765	amino acid transport
BB341_RS18455	COG0154	amidase activity
BB341_RS18465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB341_RS18500	COG0406	alpha-ribazole phosphatase activity
BB341_RS18540	COG0745	RESPONSE REGULATOR receiver
BB341_RS18555	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BB341_RS18560	COG4977	sequence-specific DNA binding
BB341_RS18570	COG0589	response to stress
BB341_RS18575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BB341_RS18600	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BB341_RS18605	COG0076	glutamate decarboxylase activity
BB341_RS18615	COG1960	acyl-CoA dehydrogenase activity
BB341_RS18630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BB341_RS18635	COG1309	transcriptional regulator
BB341_RS18645	COG2124	cytochrome p450
BB341_RS18650	COG1946	Acyl-CoA thioesterase
BB341_RS18665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BB341_RS18675	COG3960	tartronate-semialdehyde synthase activity
BB341_RS18695	COG1674	ftsk spoiiie
BB341_RS18755	COG1472	Belongs to the glycosyl hydrolase 3 family
BB341_RS18770	COG1609	Transcriptional regulator
BB341_RS18775	COG0673	inositol 2-dehydrogenase activity
BB341_RS18790	COG1595	DNA-templated transcription, initiation
BB341_RS18800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BB341_RS18825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB341_RS18835	COG3718	enzyme involved in inositol metabolism
BB341_RS18840	COG3962	Belongs to the TPP enzyme family
BB341_RS18860	COG1131	(ABC) transporter
BB341_RS18915	COG0105	UTP biosynthetic process
BB341_RS18920	COG2197	response regulator
BB341_RS18930	COG2954	triphosphatase activity
BB341_RS18940	COG0494	nUDIX hydrolase
BB341_RS18970	COG0561	phosphatase activity
BB341_RS18980	COG0475	glutathione-regulated potassium exporter activity
BB341_RS19010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BB341_RS19020	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BB341_RS19025	COG1518	maintenance of DNA repeat elements
BB341_RS19035	COG1203	CRISPR-associated helicase, Cas3
BB341_RS19075	COG0629	single-stranded DNA binding
BB341_RS19105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB341_RS19150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB341_RS19165	COG1486	melibiose metabolic process
BB341_RS19170	COG0395	ABC-type sugar transport system, permease component
BB341_RS19175	COG1175	transmembrane transport
BB341_RS19195	COG0668	transmembrane transport
BB341_RS19265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BB341_RS19270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BB341_RS19280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB341_RS19290	COG0588	phosphoglycerate mutase activity
BB341_RS19295	COG1113	amino acid transport
BB341_RS19305	COG1113	amino acid transport
BB341_RS19320	COG4552	Acetyltransferase involved in intracellular survival and related
BB341_RS19335	COG0475	glutathione-regulated potassium exporter activity
BB341_RS19350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB341_RS19355	COG3594	Acyltransferase
BB341_RS19375	COG0544	peptidyl-prolyl cis-trans isomerase activity
BB341_RS19380	COG0740	serine-type endopeptidase activity
BB341_RS19385	COG0740	serine-type endopeptidase activity
BB341_RS19390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BB341_RS19400	COG0525	valine-tRNA ligase activity
BB341_RS19405	COG4585	Histidine kinase
BB341_RS19410	COG0285	dihydrofolate synthase activity
BB341_RS19420	COG0105	UTP biosynthetic process
BB341_RS19425	COG1077	Cell shape determining protein MreB Mrl
BB341_RS19445	COG0772	Belongs to the SEDS family
BB341_RS19465	COG1530	ribonuclease E activity
BB341_RS19475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BB341_RS19480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BB341_RS19485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BB341_RS19490	COG0438	transferase activity, transferring glycosyl groups
BB341_RS19505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BB341_RS19515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BB341_RS19530	COG0501	Belongs to the peptidase M48B family
BB341_RS19535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BB341_RS19545	COG0799	negative regulation of ribosome biogenesis
BB341_RS19550	COG0588	phosphoglycerate mutase activity
BB341_RS19560	COG0495	leucyl-tRNA aminoacylation
BB341_RS19570	COG1307	EDD domain protein, DegV family
BB341_RS19610	COG0268	Binds directly to 16S ribosomal RNA
BB341_RS19615	COG0481	GTPase activity
BB341_RS19640	COG1420	regulation of RNA biosynthetic process
BB341_RS19645	COG0484	heat shock protein binding
BB341_RS19665	COG4946	Tricorn protease homolog
BB341_RS19665	COG0793	Belongs to the peptidase S41A family
BB341_RS19670	COG0537	adenosine 5'-monophosphoramidase activity
BB341_RS19675	COG1234	tRNA 3'-trailer cleavage
BB341_RS19680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BB341_RS19685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB341_RS19695	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BB341_RS19735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BB341_RS19750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB341_RS19765	COG1381	Involved in DNA repair and RecF pathway recombination
BB341_RS19770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BB341_RS19780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BB341_RS19785	COG3842	ATPase activity
BB341_RS19790	COG3443	Belongs to the bacterial solute-binding protein 9 family
BB341_RS19790	COG0803	Belongs to the bacterial solute-binding protein 9 family
BB341_RS19795	COG0423	glycine-tRNA ligase activity
BB341_RS19835	COG0574	Belongs to the PEP-utilizing enzyme family
BB341_RS19835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB341_RS19850	COG0531	amino acid
BB341_RS19860	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS19865	COG2890	protein-(glutamine-N5) methyltransferase activity
BB341_RS19885	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BB341_RS19905	COG2949	membrane
BB341_RS19910	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BB341_RS19920	COG0358	DNA primase activity
BB341_RS19925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB341_RS19940	COG1070	Carbohydrate kinase
BB341_RS19975	COG1129	ABC transporter
BB341_RS19975	COG0842	Transport permease protein
BB341_RS20030	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS20040	COG1136	(ABC) transporter
BB341_RS20095	COG2130	NADP-dependent
BB341_RS20130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BB341_RS20135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BB341_RS20140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB341_RS20165	COG0789	Transcriptional regulator
BB341_RS20170	COG0667	Aldo Keto reductase
BB341_RS20175	COG2197	response regulator
BB341_RS20180	COG4585	Histidine kinase
BB341_RS20200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB341_RS20205	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BB341_RS20255	COG1358	cellular component organization or biogenesis
BB341_RS20265	COG0586	Pfam SNARE associated Golgi protein
BB341_RS20290	COG0582	viral genome integration into host DNA
BB341_RS20390	COG4122	O-methyltransferase activity
BB341_RS20400	COG2124	cytochrome p450
BB341_RS20405	COG0183	Belongs to the thiolase family
BB341_RS20420	COG3845	ABC transporter
BB341_RS20455	COG1309	transcriptional regulator
BB341_RS20460	COG0438	transferase activity, transferring glycosyl groups
BB341_RS20465	COG2226	methyltransferase
BB341_RS20475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB341_RS20495	COG0183	Belongs to the thiolase family
BB341_RS20515	COG2030	dehydratase
BB341_RS20520	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BB341_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS20535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BB341_RS20550	COG0800	Aldolase
BB341_RS20555	COG3022	response to hydroperoxide
BB341_RS20570	COG0789	Transcriptional regulator
BB341_RS20590	COG1349	DNA-binding transcription factor activity
BB341_RS20595	COG1653	transport
BB341_RS20605	COG0395	ABC-type sugar transport system, permease component
BB341_RS20645	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS20650	COG3540	Alkaline phosphatase
BB341_RS20655	COG2814	Major facilitator Superfamily
BB341_RS20670	COG1834	amidinotransferase
BB341_RS20690	COG1120	ATPase activity
BB341_RS20695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB341_RS20720	COG5398	heme oxygenase
BB341_RS20750	COG1994	Peptidase M50
BB341_RS20770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BB341_RS20780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB341_RS20780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BB341_RS20785	COG2132	Multicopper oxidase
BB341_RS20820	COG0174	glutamine synthetase
BB341_RS20835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BB341_RS20850	COG1228	amidohydrolase
BB341_RS20865	COG2154	pterin-4-alpha-carbinolamine dehydratase
BB341_RS20885	COG2154	pterin-4-alpha-carbinolamine dehydratase
BB341_RS20905	COG1609	Transcriptional regulator
BB341_RS20910	COG0366	Alpha amylase catalytic
BB341_RS20915	COG3833	ABC-type maltose transport systems, permease component
BB341_RS20920	COG1175	transmembrane transport
BB341_RS20950	COG2197	response regulator
BB341_RS20990	COG0745	RESPONSE REGULATOR receiver
BB341_RS21000	COG0673	inositol 2-dehydrogenase activity
BB341_RS21025	COG0181	hydroxymethylbilane synthase activity
BB341_RS21070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BB341_RS21075	COG0321	lipoyl(octanoyl) transferase activity
BB341_RS21090	COG1090	epimerase
BB341_RS21120	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BB341_RS21130	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB341_RS21135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB341_RS21140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BB341_RS21145	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BB341_RS21155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BB341_RS21180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB341_RS21185	COG1132	(ABC) transporter
BB341_RS21210	COG4585	Histidine kinase
BB341_RS21215	COG2197	response regulator
BB341_RS21220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB341_RS21230	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BB341_RS21250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB341_RS21260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BB341_RS21265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB341_RS21275	COG1376	ErfK ybiS ycfS ynhG family protein
BB341_RS21285	COG1845	cytochrome c oxidase, subunit III
BB341_RS21290	COG2010	Cytochrome c
BB341_RS21295	COG0723	plastoquinol--plastocyanin reductase activity
BB341_RS21300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BB341_RS21305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BB341_RS21310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB341_RS21315	COG1929	Belongs to the glycerate kinase type-1 family
BB341_RS21325	COG0745	RESPONSE REGULATOR receiver
BB341_RS21330	COG2205	protein histidine kinase activity
BB341_RS21380	COG0438	transferase activity, transferring glycosyl groups
BB341_RS21405	COG0003	Pfam Anion-transporting ATPase
BB341_RS21415	COG1940	carbohydrate kinase activity
BB341_RS21445	COG2197	response regulator
BB341_RS21450	COG0205	6-phosphofructokinase activity
BB341_RS21460	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BB341_RS21465	COG0243	molybdopterin cofactor binding
BB341_RS21470	COG2193	ferroxidase activity
BB341_RS21475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BB341_RS21480	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BB341_RS21485	COG2815	serine threonine protein kinase
BB341_RS21485	COG0515	serine threonine protein kinase
BB341_RS21490	COG2022	thiamine diphosphate biosynthetic process
BB341_RS21500	COG2022	thiamine diphosphate biosynthetic process
BB341_RS21500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB341_RS21520	COG0352	thiamine-phosphate diphosphorylase activity
BB341_RS21535	COG1233	COG1233 Phytoene dehydrogenase and related
BB341_RS21545	COG1309	transcriptional regulator
BB341_RS21550	COG1511	domain protein
BB341_RS21555	COG1121	(ABC) transporter
BB341_RS21585	COG0714	Associated with various cellular activities
BB341_RS21600	COG0275	rRNA processing
BB341_RS21610	COG0768	penicillin binding
BB341_RS21615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BB341_RS21620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BB341_RS21625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB341_RS21630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BB341_RS21640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BB341_RS21645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BB341_RS21655	COG1496	oxidoreductase activity
BB341_RS21665	COG1799	cell septum assembly
BB341_RS21675	COG3599	regulation of cell shape
BB341_RS21680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BB341_RS21695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BB341_RS21745	COG0587	DNA-directed DNA polymerase activity
BB341_RS21750	COG1432	Conserved Protein
BB341_RS21770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BB341_RS21790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BB341_RS21795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB341_RS21800	COG0131	Imidazoleglycerol-phosphate dehydratase
BB341_RS21805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BB341_RS21810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BB341_RS21815	COG0251	oxidation-reduction process
BB341_RS21820	COG0107	imidazoleglycerol-phosphate synthase activity
BB341_RS21835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BB341_RS21840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BB341_RS21860	COG0134	indole-3-glycerol-phosphate synthase activity
BB341_RS21870	COG0133	tryptophan synthase activity
BB341_RS21875	COG0159	tryptophan synthase activity
BB341_RS21885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BB341_RS21890	COG2301	Belongs to the HpcH HpaI aldolase family
BB341_RS21895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB341_RS21900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB341_RS21930	COG0067	glutamate synthase
BB341_RS21930	COG0069	glutamate synthase activity
BB341_RS21930	COG0070	glutamate synthase
BB341_RS21955	COG1960	acyl-CoA dehydrogenase activity
BB341_RS21965	COG1309	transcriptional regulator
BB341_RS21970	COG0183	Belongs to the thiolase family
BB341_RS22000	COG1024	Enoyl-CoA hydratase
BB341_RS22010	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS22025	COG0366	Alpha amylase catalytic
BB341_RS22025	COG1470	cell adhesion involved in biofilm formation
BB341_RS22040	COG0287	Prephenate dehydrogenase
BB341_RS22040	COG1605	Chorismate mutase
BB341_RS22095	COG0411	ABC transporter
BB341_RS22115	COG2050	protein possibly involved in aromatic compounds catabolism
BB341_RS22140	COG1643	Atp-dependent helicase
BB341_RS22145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB341_RS22145	COG0596	Alpha beta hydrolase
BB341_RS22145	COG2226	methyltransferase
BB341_RS22150	COG0539	negative regulation of cytoplasmic translation
BB341_RS22160	COG0237	dephospho-CoA kinase activity
BB341_RS22180	COG0330	HflC and HflK could
BB341_RS22185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BB341_RS22215	COG2313	pseudouridylate synthase activity
BB341_RS22225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB341_RS22230	COG0584	glycerophosphoryl diester phosphodiesterase
BB341_RS22240	COG0556	nucleotide-excision repair
BB341_RS22260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BB341_RS22270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BB341_RS22275	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BB341_RS22275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BB341_RS22300	COG0322	excinuclease ABC activity
BB341_RS22305	COG1660	Displays ATPase and GTPase activities
BB341_RS22310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BB341_RS22315	COG1481	regulation of sporulation
BB341_RS22325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BB341_RS22330	COG0126	phosphoglycerate kinase activity
BB341_RS22335	COG0149	triose-phosphate isomerase activity
BB341_RS22340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB341_RS22350	COG0166	Belongs to the GPI family
BB341_RS22355	COG3402	PFAM membrane-flanked domain
BB341_RS22365	COG0363	glucosamine-6-phosphate deaminase activity
BB341_RS22380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BB341_RS22390	COG0109	protoheme IX farnesyltransferase activity
BB341_RS22420	COG1131	(ABC) transporter
BB341_RS22435	COG0719	Fe-S assembly protein
BB341_RS22445	COG0396	ATPase activity
BB341_RS22450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB341_RS22455	COG0822	iron-sulfur transferase activity
BB341_RS22460	COG2151	metal-sulfur cluster biosynthetic enzyme
BB341_RS22465	COG2171	N-acyltransferase activity
BB341_RS22475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB341_RS22525	COG2205	protein histidine kinase activity
BB341_RS22530	COG0745	RESPONSE REGULATOR receiver
BB341_RS22545	COG1802	Transcriptional regulator
BB341_RS22560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB341_RS22565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB341_RS22575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB341_RS22585	COG0768	penicillin binding
BB341_RS22590	COG2197	response regulator
BB341_RS22595	COG4585	Histidine kinase
BB341_RS22600	COG1414	Transcriptional regulator
BB341_RS22625	COG1902	pentaerythritol trinitrate reductase activity
BB341_RS22630	COG5285	phytanoyl-CoA dioxygenase
BB341_RS22635	COG1917	Cupin 2, conserved barrel domain protein
BB341_RS22650	COG0134	indole-3-glycerol-phosphate synthase activity
BB341_RS22685	COG1797	cobyrinic acid a,c-diamide synthase activity
BB341_RS22700	COG1492	cobalamin metabolic process
BB341_RS22705	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BB341_RS22720	COG0235	Class ii aldolase
BB341_RS22735	COG0488	(ABC) transporter
BB341_RS22745	COG1024	Enoyl-CoA hydratase
BB341_RS22785	COG3387	PFAM Glycoside hydrolase 15-related
BB341_RS22820	COG1404	Belongs to the peptidase S8 family
BB341_RS22830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BB341_RS22835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BB341_RS22855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BB341_RS22870	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS22875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BB341_RS22880	COG2186	Transcriptional regulator
BB341_RS22885	COG2807	transmembrane transport
BB341_RS22900	COG0560	Phosphoserine phosphatase
BB341_RS22900	COG3830	Belongs to the UPF0237 family
BB341_RS22905	COG0842	Transport permease protein
BB341_RS22905	COG1131	(ABC) transporter
BB341_RS22905	COG1716	ATPase activity
BB341_RS22915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BB341_RS22925	COG4585	Histidine kinase
BB341_RS22930	COG2197	response regulator
BB341_RS22945	COG1119	ATPase activity
BB341_RS22970	COG1881	PFAM PEBP family protein
BB341_RS22980	COG2094	Belongs to the DNA glycosylase MPG family
BB341_RS23015	COG0647	UMP catabolic process
BB341_RS23020	COG1120	ATPase activity
BB341_RS23040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BB341_RS23045	COG0497	DNA recombination
BB341_RS23050	COG0297	glycogen (starch) synthase activity
BB341_RS23060	COG3387	PFAM Glycoside hydrolase 15-related
BB341_RS23065	COG0504	CTP synthase activity
BB341_RS23070	COG0494	nUDIX hydrolase
BB341_RS23080	COG0686	Belongs to the AlaDH PNT family
BB341_RS23095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BB341_RS23100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BB341_RS23105	COG1187	pseudouridine synthase activity
BB341_RS23110	COG1051	belongs to the nudix hydrolase family
BB341_RS23110	COG1056	cytidyltransferase-related domain
BB341_RS23135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BB341_RS23145	COG1160	GTP binding
BB341_RS23165	COG0438	transferase activity, transferring glycosyl groups
BB341_RS23170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB341_RS23180	COG0671	phosphoesterase, PA-phosphatase related
BB341_RS23185	COG0477	Major facilitator Superfamily
BB341_RS23190	COG1960	acyl-CoA dehydrogenase activity
BB341_RS23195	COG1799	cell septum assembly
BB341_RS23240	COG0641	radical SAM
BB341_RS23255	COG3903	Transcriptional regulator
BB341_RS23255	COG3629	intracellular signal transduction
BB341_RS23260	COG0596	Alpha beta hydrolase
BB341_RS23285	COG4565	transcriptional regulatory protein
BB341_RS23310	COG1725	Transcriptional regulator
BB341_RS23320	COG2755	lipolytic protein G-D-S-L family
BB341_RS23330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB341_RS23335	COG2188	Transcriptional regulator
BB341_RS23340	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BB341_RS23345	COG2851	Citrate transporter
BB341_RS23380	COG3876	Protein conserved in bacteria
BB341_RS23395	COG1960	acyl-CoA dehydrogenase activity
BB341_RS23410	COG2149	membrane
BB341_RS23415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BB341_RS23430	COG3265	gluconokinase activity
BB341_RS23435	COG2186	Transcriptional regulator
BB341_RS23440	COG1113	amino acid transport
BB341_RS23470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB341_RS23500	COG0667	Aldo Keto reductase
BB341_RS23505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB341_RS23515	COG0598	Magnesium transport protein CorA
BB341_RS23535	COG0215	cysteine-tRNA ligase activity
BB341_RS23545	COG4948	Mandelate Racemase Muconate Lactonizing
BB341_RS23550	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS23560	COG1129	ABC transporter
BB341_RS23570	COG2186	Transcriptional regulator
BB341_RS23575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BB341_RS23580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BB341_RS23585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB341_RS23590	COG1414	Transcriptional regulator
BB341_RS23595	COG1410	methionine synthase
BB341_RS23595	COG0646	methionine synthase
BB341_RS23600	COG0438	transferase activity, transferring glycosyl groups
BB341_RS23615	COG2197	response regulator
BB341_RS23625	COG1994	Peptidase M50
BB341_RS23625	COG0517	IMP dehydrogenase activity
BB341_RS23645	COG1222	aaa ATPase
BB341_RS23650	COG4122	O-methyltransferase activity
BB341_RS23660	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BB341_RS23665	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BB341_RS23670	COG1609	Transcriptional regulator
BB341_RS23680	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BB341_RS23715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB341_RS23720	COG0805	protein transport
BB341_RS23755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BB341_RS23760	COG0517	IMP dehydrogenase activity
BB341_RS23760	COG4175	Glycine betaine
BB341_RS23785	COG1113	amino acid transport
BB341_RS23790	COG2186	Transcriptional regulator
BB341_RS23795	COG0174	glutamine synthetase
BB341_RS23820	COG1404	Belongs to the peptidase S8 family
BB341_RS23840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BB341_RS23845	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BB341_RS23850	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BB341_RS23855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB341_RS23860	COG5002	protein histidine kinase activity
BB341_RS23865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BB341_RS23870	COG0072	phenylalanine-tRNA ligase activity
BB341_RS23870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB341_RS23890	COG1649	PFAM Uncharacterised BCR, COG1649
BB341_RS23900	COG0697	spore germination
BB341_RS23910	COG2838	Isocitrate dehydrogenase
BB341_RS23935	COG4585	Histidine kinase
BB341_RS23940	COG2197	response regulator
BB341_RS23945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BB341_RS23950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BB341_RS23955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BB341_RS23960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB341_RS23965	COG1438	arginine binding
BB341_RS23970	COG0137	argininosuccinate synthase activity
BB341_RS23975	COG0165	Argininosuccinate lyase
BB341_RS23985	COG0477	Major facilitator Superfamily
BB341_RS23990	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS23990	COG0204	Acyl-transferase
BB341_RS23995	COG0584	glycerophosphoryl diester phosphodiesterase
BB341_RS24015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BB341_RS24020	COG2011	ABC-type metal ion transport system permease component
BB341_RS24025	COG1464	Belongs to the NlpA lipoprotein family
BB341_RS24040	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BB341_RS24045	COG1648	precorrin-2 dehydrogenase activity
BB341_RS24045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BB341_RS24090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BB341_RS24100	COG0456	acetyltransferase
BB341_RS24145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BB341_RS24150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BB341_RS24155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BB341_RS24175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BB341_RS24180	COG1560	Kdo2-lipid A biosynthetic process
BB341_RS24185	COG0438	transferase activity, transferring glycosyl groups
BB341_RS24195	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BB341_RS24200	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BB341_RS24205	COG0217	transcriptional regulatory protein
BB341_RS24210	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BB341_RS24215	COG0632	four-way junction helicase activity
BB341_RS24220	COG2255	four-way junction helicase activity
BB341_RS24230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB341_RS24235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB341_RS24240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BB341_RS24245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB341_RS24255	COG1196	nuclear chromosome segregation
BB341_RS24260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BB341_RS24270	COG0124	histidyl-tRNA synthetase
BB341_RS24290	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BB341_RS24305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BB341_RS24310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BB341_RS24315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BB341_RS24320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BB341_RS24325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BB341_RS24330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BB341_RS24335	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BB341_RS24340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BB341_RS24350	COG0006	proline dipeptidase activity
BB341_RS24355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BB341_RS24360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB341_RS24370	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BB341_RS24375	COG0540	Belongs to the ATCase OTCase family
BB341_RS24380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BB341_RS24390	COG0505	Belongs to the CarA family
BB341_RS24395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BB341_RS24400	COG0167	dihydroorotate dehydrogenase activity
BB341_RS24405	COG0284	orotidine-5'-phosphate decarboxylase activity
BB341_RS24430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BB341_RS24445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB341_RS24455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BB341_RS24460	COG2390	Transcriptional regulator
BB341_RS24490	COG1191	sigma factor activity
BB341_RS24500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB341_RS24515	COG2233	PERMEase
BB341_RS24525	COG0738	Major facilitator superfamily
BB341_RS24530	COG1940	carbohydrate kinase activity
BB341_RS24530	COG1846	Transcriptional regulator
BB341_RS24545	COG3201	nicotinamide mononucleotide transporter
BB341_RS24550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BB341_RS24550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BB341_RS24555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BB341_RS24560	COG0140	phosphoribosyl-ATP diphosphatase activity
BB341_RS24565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BB341_RS24600	COG1309	transcriptional regulator
BB341_RS24605	COG1960	acyl-CoA dehydrogenase activity
BB341_RS24625	COG1216	Glycosyl transferase, family 2
BB341_RS24640	COG2270	Major facilitator Superfamily
BB341_RS24650	COG2364	Membrane
BB341_RS24655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB341_RS24685	COG1984	allophanate hydrolase subunit 2
BB341_RS24690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BB341_RS24695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BB341_RS24700	COG2814	Major facilitator Superfamily
BB341_RS24730	COG5002	protein histidine kinase activity
BB341_RS24735	COG2018	Roadblock/LC7 domain
BB341_RS24750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BB341_RS24755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB341_RS24760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB341_RS24780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB341_RS24790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB341_RS24820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BB341_RS24840	COG1716	ATPase activity
BB341_RS24860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BB341_RS24870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BB341_RS24870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BB341_RS24935	COG0697	spore germination
BB341_RS24990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BB341_RS25005	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BB341_RS25015	COG2813	Specifically methylates the guanine in position
BB341_RS25030	COG1968	undecaprenyl-diphosphatase activity
BB341_RS25045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BB341_RS25070	COG2124	cytochrome p450
BB341_RS25100	COG0110	maltose O-acetyltransferase activity
BB341_RS25105	COG1832	CoA-binding protein
BB341_RS25110	COG1739	Uncharacterized protein family UPF0029
BB341_RS25120	COG0666	response to abiotic stimulus
BB341_RS25125	COG0420	3'-5' exonuclease activity
BB341_RS25130	COG0419	ATPase involved in DNA repair
BB341_RS25130	COG0419	ATPase involved in DNA repair
BB341_RS25135	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS25165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB341_RS25180	COG2188	Transcriptional regulator
BB341_RS25185	COG1940	carbohydrate kinase activity
BB341_RS25195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BB341_RS25230	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BB341_RS25235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB341_RS25240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BB341_RS25260	COG0740	serine-type endopeptidase activity
BB341_RS25270	COG0831	urea catabolic process
BB341_RS25275	COG0832	Belongs to the urease beta subunit family
BB341_RS25280	COG0804	urea catabolic process
BB341_RS25290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BB341_RS25295	COG0829	nickel cation binding
BB341_RS25305	COG0204	Acyl-transferase
BB341_RS25320	COG0142	geranyltranstransferase activity
BB341_RS25325	COG0142	geranyltranstransferase activity
BB341_RS25340	COG0205	6-phosphofructokinase activity
BB341_RS25345	COG3442	glutamine amidotransferase
BB341_RS25355	COG0242	peptide deformylase activity
BB341_RS25365	COG1960	acyl-CoA dehydrogenase activity
BB341_RS25390	COG0386	Belongs to the glutathione peroxidase family
BB341_RS25395	COG1946	Acyl-CoA thioesterase
BB341_RS25415	COG1132	(ABC) transporter
BB341_RS25415	COG2375	cellular response to nickel ion
BB341_RS25420	COG1132	(ABC) transporter
BB341_RS25430	COG2409	Drug exporters of the RND superfamily
BB341_RS25445	COG2124	cytochrome p450
BB341_RS25455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB341_RS25465	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS25480	COG0477	Major facilitator Superfamily
BB341_RS25510	COG4585	Histidine kinase
BB341_RS25515	COG2197	response regulator
BB341_RS25535	COG2409	Drug exporters of the RND superfamily
BB341_RS25545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BB341_RS25545	COG0674	pyruvate-flavodoxin oxidoreductase activity
BB341_RS25600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB341_RS25605	COG3321	synthase
BB341_RS25605	COG0604	alcohol dehydrogenase
BB341_RS25620	COG1960	acyl-CoA dehydrogenase activity
BB341_RS25640	COG1132	(ABC) transporter
BB341_RS25645	COG2072	flavoprotein involved in K transport
BB341_RS25705	COG0443	Heat shock 70 kDa protein
BB341_RS25720	COG1309	transcriptional regulator
BB341_RS25730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB341_RS25735	COG1902	pentaerythritol trinitrate reductase activity
BB341_RS25770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BB341_RS25815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB341_RS25820	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB341_RS25825	COG1120	ATPase activity
BB341_RS25835	COG1132	(ABC) transporter
BB341_RS25860	COG4607	ABC-type enterochelin transport system periplasmic component
BB341_RS25865	COG0464	growth
BB341_RS25870	COG1404	Belongs to the peptidase S8 family
BB341_RS25875	COG1674	ftsk spoiiie
BB341_RS25940	COG1278	Cold shock
BB341_RS25955	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BB341_RS25965	COG1136	(ABC) transporter
BB341_RS25965	COG0577	efflux transmembrane transporter activity
BB341_RS25970	COG0577	efflux transmembrane transporter activity
BB341_RS25970	COG1136	(ABC) transporter
BB341_RS25985	COG0745	RESPONSE REGULATOR receiver
BB341_RS25990	COG2205	protein histidine kinase activity
BB341_RS26020	COG0463	Glycosyl transferase, family 2
BB341_RS26025	COG0326	Molecular chaperone. Has ATPase activity
BB341_RS26065	COG0309	Hydrogenase expression formation protein (HypE)
BB341_RS26075	COG0298	carbon dioxide binding
BB341_RS26085	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BB341_RS26090	COG0375	protein maturation
BB341_RS26170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB341_RS26205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BB341_RS26220	COG2706	6-phosphogluconolactonase activity
BB341_RS26235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BB341_RS26260	COG1309	transcriptional regulator
BB341_RS26265	COG0671	phosphoesterase, PA-phosphatase related
BB341_RS26290	COG0584	glycerophosphoryl diester phosphodiesterase
BB341_RS26310	COG0204	Acyl-transferase
BB341_RS26320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BB341_RS26340	COG3345	alpha-galactosidase
BB341_RS26350	COG1175	transmembrane transport
BB341_RS26355	COG0395	ABC-type sugar transport system, permease component
BB341_RS26375	COG0644	oxidoreductase
BB341_RS26390	COG1940	carbohydrate kinase activity
BB341_RS26410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BB341_RS26420	COG1349	DNA-binding transcription factor activity
BB341_RS26440	COG1215	transferase activity, transferring glycosyl groups
BB341_RS26445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BB341_RS26530	COG1486	melibiose metabolic process
BB341_RS26575	COG1012	belongs to the aldehyde dehydrogenase family
BB341_RS26580	COG0363	glucosamine-6-phosphate deaminase activity
BB341_RS26600	COG1461	Dihydroxyacetone kinase
BB341_RS26605	COG2376	Dihydroxyacetone kinase
BB341_RS26640	COG1131	(ABC) transporter
BB341_RS26695	COG1846	Transcriptional regulator
BB341_RS26730	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
BB341_RS26735	COG1959	2 iron, 2 sulfur cluster binding
BB341_RS26740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB341_RS26740	COG1017	nitric oxide dioxygenase activity
BB341_RS26760	COG3511	phospholipase C
BB341_RS26770	COG1796	DNA polymerase
BB341_RS26770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BB341_RS26780	COG2814	Major facilitator Superfamily
BB341_RS26820	COG1960	acyl-CoA dehydrogenase activity
BB341_RS26830	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BB341_RS26845	COG1335	isochorismatase
BB341_RS26850	COG0010	Belongs to the arginase family
BB341_RS26855	COG1181	Belongs to the D-alanine--D-alanine ligase family
BB341_RS26895	COG0701	Predicted permease
BB341_RS26905	COG2815	serine threonine protein kinase
BB341_RS26905	COG0515	serine threonine protein kinase
BB341_RS26915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BB341_RS26920	COG2070	2-Nitropropane dioxygenase
BB341_RS26930	COG0387	Pfam Sodium calcium exchanger
BB341_RS26935	COG2267	carboxylic ester hydrolase activity
BB341_RS26940	COG0318	PFAM AMP-dependent synthetase and ligase
BB341_RS27005	COG2375	cellular response to nickel ion
BB341_RS27005	COG1132	(ABC) transporter
BB341_RS27020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB341_RS27020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB341_RS27030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB341_RS27035	COG0765	amino acid transport
BB341_RS27040	COG1126	abc transporter atp-binding protein
BB341_RS27065	COG1957	nucleoside hydrolase
BB341_RS27075	COG2318	DinB family
BB341_RS27095	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB341_RS27100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB341_RS27145	COG0501	Belongs to the peptidase M48B family
BB341_RS27190	COG1404	Belongs to the peptidase S8 family
BB341_RS27190	COG4412	M6 family metalloprotease domain protein
BB341_RS27190	COG1404	Belongs to the peptidase S8 family
BB341_RS27190	COG4412	M6 family metalloprotease domain protein
BB341_RS27245	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BB341_RS27260	COG1028	Short-chain dehydrogenase reductase Sdr
BB341_RS27295	COG0288	reversible hydration of carbon dioxide
BB341_RS27305	COG0702	epimerase
BB341_RS27315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB341_RS27330	COG2226	methyltransferase
BB341_RS27340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BB341_RS27345	COG1937	Protein conserved in bacteria
BB341_RS27375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BB341_RS27435	COG0142	geranyltranstransferase activity
BB341_RS27445	COG1132	(ABC) transporter
BB341_RS27455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB341_RS27665	COG3321	synthase
BB341_RS27665	COG0604	alcohol dehydrogenase
BB341_RS27670	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB341_RS27725	COG2801	Transposase and inactivated derivatives
BB341_RS27785	COG1966	Carbon starvation protein
BB341_RS27840	COG0569	domain protein
BB341_RS27840	COG0475	glutathione-regulated potassium exporter activity
BB341_RS28615	COG2124	cytochrome p450
BB341_RS29250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB341_RS29250	COG0574	Belongs to the PEP-utilizing enzyme family
BB341_RS29415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BB341_RS29525	COG2755	lipolytic protein G-D-S-L family
BB341_RS29525	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BB341_RS29540	COG2205	protein histidine kinase activity
BB341_RS29635	COG1053	succinate dehydrogenase
BB341_RS29705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BB341_RS29950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BB341_RS30420	COG3511	phospholipase C
BB341_RS30500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BB341_RS30500	COG3433	isochorismatase activity
BB341_RS30500	COG2226	methyltransferase