locus-tag	class	description
TU94_RS00025	COG2856	Zn peptidase
TU94_RS00085	COG0420	3'-5' exonuclease activity
TU94_RS00090	COG0419	ATPase involved in DNA repair
TU94_RS00125	COG4974	Belongs to the 'phage' integrase family
TU94_RS00155	COG2801	Transposase and inactivated derivatives
TU94_RS00180	COG1136	(ABC) transporter
TU94_RS00180	COG0577	efflux transmembrane transporter activity
TU94_RS00185	COG0577	efflux transmembrane transporter activity
TU94_RS00185	COG1136	(ABC) transporter
TU94_RS00215	COG3293	Transposase
TU94_RS00460	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS00490	COG0463	Glycosyl transferase, family 2
TU94_RS00505	COG0583	DNA-binding transcription factor activity
TU94_RS00540	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS00600	COG1595	DNA-templated transcription, initiation
TU94_RS00640	COG1335	isochorismatase
TU94_RS00645	COG2814	Major facilitator Superfamily
TU94_RS00660	COG2197	response regulator
TU94_RS00665	COG4585	Histidine kinase
TU94_RS00730	COG0022	dehydrogenase e1 component
TU94_RS00735	COG0508	dehydrogenase complex catalyzes the overall conversion of
TU94_RS00770	COG2814	Major facilitator Superfamily
TU94_RS00790	COG1597	lipid kinase activity
TU94_RS00800	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS00810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TU94_RS00830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TU94_RS00840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TU94_RS00845	COG3629	intracellular signal transduction
TU94_RS00855	COG0477	Major facilitator Superfamily
TU94_RS00900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TU94_RS00915	COG3629	intracellular signal transduction
TU94_RS00920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS00930	COG2867	negative regulation of translational initiation
TU94_RS00950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TU94_RS01000	COG2814	Major facilitator Superfamily
TU94_RS01005	COG1473	amidohydrolase
TU94_RS01040	COG1953	Uracil, thiamine, allantoin
TU94_RS01065	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS01090	COG4552	Acetyltransferase involved in intracellular survival and related
TU94_RS01150	COG1278	Cold shock
TU94_RS01185	COG2124	cytochrome p450
TU94_RS01225	COG2135	peptidase activity
TU94_RS01230	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
TU94_RS01255	COG0531	amino acid
TU94_RS01260	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TU94_RS01280	COG0583	DNA-binding transcription factor activity
TU94_RS01295	COG2814	Major facilitator Superfamily
TU94_RS01340	COG4585	Histidine kinase
TU94_RS01345	COG2197	response regulator
TU94_RS01360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TU94_RS01365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS01370	COG1132	(ABC) transporter
TU94_RS01425	COG1073	alpha beta
TU94_RS01430	COG0477	Major facilitator Superfamily
TU94_RS01435	COG0702	epimerase
TU94_RS01480	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
TU94_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS01515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TU94_RS01540	COG2208	phosphoserine phosphatase activity
TU94_RS01540	COG2770	Histidine kinase
TU94_RS01565	COG0456	acetyltransferase
TU94_RS01575	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
TU94_RS01595	COG0859	PFAM glycosyl transferase family 9
TU94_RS01625	COG0753	catalase activity
TU94_RS01660	COG0009	L-threonylcarbamoyladenylate synthase
TU94_RS01685	COG2207	Transcriptional regulator
TU94_RS01690	COG2223	nitrite transmembrane transporter activity
TU94_RS01695	COG3285	dna ligase
TU94_RS01695	COG1793	dna ligase
TU94_RS01705	COG0181	hydroxymethylbilane synthase activity
TU94_RS01745	COG0366	Alpha amylase catalytic
TU94_RS01755	COG3281	Trehalose synthase
TU94_RS01760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TU94_RS01765	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
TU94_RS01790	COG2205	protein histidine kinase activity
TU94_RS01800	COG0784	Response regulator, receiver
TU94_RS01800	COG2205	protein histidine kinase activity
TU94_RS01800	COG5002	protein histidine kinase activity
TU94_RS01815	COG1366	Belongs to the anti-sigma-factor antagonist family
TU94_RS01820	COG1366	Belongs to the anti-sigma-factor antagonist family
TU94_RS01825	COG2172	sigma factor antagonist activity
TU94_RS01880	COG1982	Orn Lys Arg decarboxylase major
TU94_RS01890	COG0477	Major facilitator Superfamily
TU94_RS01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS01970	COG0667	Aldo Keto reductase
TU94_RS01985	COG0328	RNA-DNA hybrid ribonuclease activity
TU94_RS02000	COG0740	serine-type endopeptidase activity
TU94_RS02005	COG0740	serine-type endopeptidase activity
TU94_RS02015	COG1191	sigma factor activity
TU94_RS02035	COG0667	Aldo Keto reductase
TU94_RS02040	COG0583	DNA-binding transcription factor activity
TU94_RS02050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TU94_RS02060	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS02105	COG0673	inositol 2-dehydrogenase activity
TU94_RS02150	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS02160	COG2235	arginine
TU94_RS02170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS02205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TU94_RS02210	COG0640	Transcriptional regulator
TU94_RS02215	COG0346	lactoylglutathione lyase activity
TU94_RS02220	COG2814	Major facilitator Superfamily
TU94_RS02235	COG3479	Phenolic acid decarboxylase
TU94_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS02315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TU94_RS02330	COG0662	Cupin 2, conserved barrel domain protein
TU94_RS02360	COG0789	Transcriptional regulator
TU94_RS02380	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
TU94_RS02385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
TU94_RS02390	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
TU94_RS02405	COG2814	Major facilitator Superfamily
TU94_RS02450	COG2124	cytochrome p450
TU94_RS02500	COG1228	amidohydrolase
TU94_RS02535	COG2072	flavoprotein involved in K transport
TU94_RS02540	COG0798	PFAM Bile acid sodium symporter
TU94_RS02550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TU94_RS02560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TU94_RS02575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TU94_RS02590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TU94_RS02595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TU94_RS02600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TU94_RS02605	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TU94_RS02615	COG0019	diaminopimelate decarboxylase activity
TU94_RS02635	COG0531	amino acid
TU94_RS02645	COG0667	Aldo Keto reductase
TU94_RS02685	COG0446	pyridine nucleotide-disulphide oxidoreductase
TU94_RS02685	COG1902	pentaerythritol trinitrate reductase activity
TU94_RS02700	COG2890	protein-(glutamine-N5) methyltransferase activity
TU94_RS02715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TU94_RS02730	COG3458	cephalosporin-C deacetylase activity
TU94_RS02735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS02745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TU94_RS02750	COG1686	Belongs to the peptidase S11 family
TU94_RS02755	COG2066	Belongs to the glutaminase family
TU94_RS02770	COG2186	Transcriptional regulator
TU94_RS02780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TU94_RS02785	COG1993	acr, cog1993
TU94_RS02790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TU94_RS02815	COG1175	transmembrane transport
TU94_RS02870	COG1609	Transcriptional regulator
TU94_RS02875	COG1247	-acetyltransferase
TU94_RS02880	COG0640	Transcriptional regulator
TU94_RS02890	COG0673	inositol 2-dehydrogenase activity
TU94_RS02900	COG2755	lipolytic protein G-D-S-L family
TU94_RS02925	COG2124	cytochrome p450
TU94_RS02930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TU94_RS02930	COG2070	2-Nitropropane dioxygenase
TU94_RS02935	COG0300	oxidoreductase activity
TU94_RS02935	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS02935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS02935	COG3321	synthase
TU94_RS02950	COG3321	synthase
TU94_RS02950	COG4221	oxidoreductase activity
TU94_RS02950	COG0300	oxidoreductase activity
TU94_RS02950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TU94_RS02965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TU94_RS02975	COG0604	alcohol dehydrogenase
TU94_RS02975	COG3321	synthase
TU94_RS02980	COG2508	Transcriptional regulator
TU94_RS02990	COG3321	synthase
TU94_RS02995	COG3321	synthase
TU94_RS03005	COG3320	Male sterility
TU94_RS03005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TU94_RS03020	COG1960	acyl-CoA dehydrogenase activity
TU94_RS03035	COG0604	alcohol dehydrogenase
TU94_RS03035	COG3321	synthase
TU94_RS03045	COG0604	alcohol dehydrogenase
TU94_RS03045	COG3321	synthase
TU94_RS03075	COG1250	3-hydroxyacyl-CoA dehydrogenase
TU94_RS03090	COG0300	oxidoreductase activity
TU94_RS03110	COG0438	transferase activity, transferring glycosyl groups
TU94_RS03120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TU94_RS03125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TU94_RS03155	COG1461	Dihydroxyacetone kinase
TU94_RS03160	COG2376	Dihydroxyacetone kinase
TU94_RS03175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS03225	COG0367	asparagine synthase
TU94_RS03230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
TU94_RS03230	COG2308	Evidence 4 Homologs of previously reported genes of
TU94_RS03270	COG3321	synthase
TU94_RS03270	COG0604	alcohol dehydrogenase
TU94_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS03325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TU94_RS03345	COG2770	Histidine kinase
TU94_RS03345	COG2208	phosphoserine phosphatase activity
TU94_RS03350	COG0596	Alpha beta hydrolase
TU94_RS03410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TU94_RS03415	COG2072	flavoprotein involved in K transport
TU94_RS03430	COG3507	Belongs to the glycosyl hydrolase 43 family
TU94_RS03440	COG0488	(ABC) transporter
TU94_RS03450	COG3226	Transcriptional regulator
TU94_RS03480	COG2986	histidine ammonia-lyase
TU94_RS03490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
TU94_RS03495	COG2188	Transcriptional regulator
TU94_RS03525	COG1309	transcriptional regulator
TU94_RS03540	COG1063	alcohol dehydrogenase
TU94_RS03560	COG0366	Alpha amylase catalytic
TU94_RS03565	COG0395	ABC-type sugar transport system, permease component
TU94_RS03570	COG1175	transmembrane transport
TU94_RS03640	COG3959	Transketolase, thiamine diphosphate binding domain
TU94_RS03645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TU94_RS03650	COG1937	Protein conserved in bacteria
TU94_RS03655	COG0730	response to heat
TU94_RS03680	COG0726	polysaccharide deacetylase
TU94_RS03690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TU94_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS03735	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS03740	COG5285	phytanoyl-CoA dioxygenase
TU94_RS03760	COG1960	acyl-CoA dehydrogenase activity
TU94_RS03765	COG2235	arginine
TU94_RS03770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TU94_RS03790	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS03815	COG1215	transferase activity, transferring glycosyl groups
TU94_RS03845	COG1349	DNA-binding transcription factor activity
TU94_RS03885	COG1940	carbohydrate kinase activity
TU94_RS03895	COG2813	Specifically methylates the guanine in position
TU94_RS03905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TU94_RS03945	COG0783	Belongs to the Dps family
TU94_RS03955	COG1501	Belongs to the glycosyl hydrolase 31 family
TU94_RS03960	COG1653	transport
TU94_RS03975	COG1175	transmembrane transport
TU94_RS03980	COG0395	ABC-type sugar transport system, permease component
TU94_RS03990	COG1940	carbohydrate kinase activity
TU94_RS04010	COG0445	tRNA wobble uridine modification
TU94_RS04020	COG1660	Displays ATPase and GTPase activities
TU94_RS04045	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TU94_RS04065	COG0204	Acyl-transferase
TU94_RS04100	COG0584	glycerophosphoryl diester phosphodiesterase
TU94_RS04140	COG0671	phosphoesterase, PA-phosphatase related
TU94_RS04150	COG1309	transcriptional regulator
TU94_RS04170	COG0493	'glutamate synthase
TU94_RS04180	COG0640	Transcriptional regulator
TU94_RS04185	COG1902	pentaerythritol trinitrate reductase activity
TU94_RS04190	COG3509	depolymerase
TU94_RS04205	COG1301	dicarboxylic acid transport
TU94_RS04210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS04225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS04245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS04255	COG1509	lysine 2,3-aminomutase activity
TU94_RS04260	COG2192	nodulation
TU94_RS04275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TU94_RS04290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS04295	COG0174	glutamine synthetase
TU94_RS04300	COG0149	triose-phosphate isomerase activity
TU94_RS04315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
TU94_RS04320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
TU94_RS04350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TU94_RS04360	COG4770	biotin carboxylase activity
TU94_RS04400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
TU94_RS04405	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
TU94_RS04410	COG2080	2 iron, 2 sulfur cluster binding
TU94_RS04435	COG4565	transcriptional regulatory protein
TU94_RS04485	COG0432	Pfam Uncharacterised protein family UPF0047
TU94_RS04490	COG2072	flavoprotein involved in K transport
TU94_RS04500	COG1132	(ABC) transporter
TU94_RS04505	COG1846	Transcriptional regulator
TU94_RS04520	COG1132	(ABC) transporter
TU94_RS04530	COG0254	rRNA binding
TU94_RS04545	COG1946	Acyl-CoA thioesterase
TU94_RS04555	COG2018	Roadblock/LC7 domain
TU94_RS04590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TU94_RS04600	COG0494	nUDIX hydrolase
TU94_RS04610	COG1070	Carbohydrate kinase
TU94_RS04615	COG1940	carbohydrate kinase activity
TU94_RS04615	COG1846	Transcriptional regulator
TU94_RS04645	COG1472	Belongs to the glycosyl hydrolase 3 family
TU94_RS04665	COG0477	Major facilitator Superfamily
TU94_RS04690	COG1960	acyl-CoA dehydrogenase activity
TU94_RS04695	COG1960	acyl-CoA dehydrogenase activity
TU94_RS04715	COG1793	dna ligase
TU94_RS04725	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS04740	COG1960	acyl-CoA dehydrogenase activity
TU94_RS04750	COG0242	peptide deformylase activity
TU94_RS04760	COG3442	glutamine amidotransferase
TU94_RS04765	COG0205	6-phosphofructokinase activity
TU94_RS04780	COG3275	phosphorelay sensor kinase activity
TU94_RS04785	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TU94_RS04795	COG3279	Response regulator of the LytR AlgR family
TU94_RS04800	COG1522	sequence-specific DNA binding
TU94_RS04805	COG1834	amidinotransferase
TU94_RS04810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TU94_RS04815	COG0698	ribose 5-phosphate isomerase
TU94_RS04845	COG4932	domain protein
TU94_RS04845	COG3266	domain, Protein
TU94_RS04845	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
TU94_RS04855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS04870	COG1024	Enoyl-CoA hydratase
TU94_RS04875	COG1024	Enoyl-CoA hydratase
TU94_RS04880	COG3424	synthase
TU94_RS04940	COG0204	Acyl-transferase
TU94_RS04955	COG0829	nickel cation binding
TU94_RS04960	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
TU94_RS04970	COG0804	urea catabolic process
TU94_RS04975	COG0832	Belongs to the urease beta subunit family
TU94_RS04980	COG0831	urea catabolic process
TU94_RS04985	COG1309	transcriptional regulator
TU94_RS05000	COG0740	serine-type endopeptidase activity
TU94_RS05035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TU94_RS05040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TU94_RS05045	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
TU94_RS05060	COG2226	methyltransferase
TU94_RS05075	COG1136	(ABC) transporter
TU94_RS05075	COG0577	efflux transmembrane transporter activity
TU94_RS05080	COG0577	efflux transmembrane transporter activity
TU94_RS05080	COG1136	(ABC) transporter
TU94_RS05090	COG0456	acetyltransferase
TU94_RS05125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TU94_RS05140	COG1940	carbohydrate kinase activity
TU94_RS05150	COG1595	DNA-templated transcription, initiation
TU94_RS05180	COG0626	cystathionine gamma-synthase activity
TU94_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS05205	COG1522	sequence-specific DNA binding
TU94_RS05210	COG0419	ATPase involved in DNA repair
TU94_RS05215	COG0420	3'-5' exonuclease activity
TU94_RS05235	COG1739	Uncharacterized protein family UPF0029
TU94_RS05240	COG1832	CoA-binding protein
TU94_RS05265	COG0110	maltose O-acetyltransferase activity
TU94_RS05295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TU94_RS05305	COG1968	undecaprenyl-diphosphatase activity
TU94_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS05350	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TU94_RS05360	COG2318	DinB family
TU94_RS05375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
TU94_RS05380	COG0747	negative chemotaxis
TU94_RS05415	COG1132	(ABC) transporter
TU94_RS05430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TU94_RS05450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TU94_RS05465	COG0367	asparagine synthase
TU94_RS05480	COG2508	Transcriptional regulator
TU94_RS05485	COG2264	protein methyltransferase activity
TU94_RS05495	COG2197	response regulator
TU94_RS05505	COG0697	spore germination
TU94_RS05550	COG0384	phenazine biosynthesis protein PhzF
TU94_RS05595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TU94_RS05595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TU94_RS05605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TU94_RS05625	COG1716	ATPase activity
TU94_RS05645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TU94_RS05675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TU94_RS05685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TU94_RS05700	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
TU94_RS05710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TU94_RS05715	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TU94_RS05730	COG2018	Roadblock/LC7 domain
TU94_RS05765	COG2814	Major facilitator Superfamily
TU94_RS05770	COG4336	lyase activity
TU94_RS05775	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TU94_RS05780	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TU94_RS05785	COG1984	allophanate hydrolase subunit 2
TU94_RS05795	COG0438	transferase activity, transferring glycosyl groups
TU94_RS05800	COG0438	transferase activity, transferring glycosyl groups
TU94_RS05830	COG2364	Membrane
TU94_RS05840	COG2270	Major facilitator Superfamily
TU94_RS05855	COG1216	Glycosyl transferase, family 2
TU94_RS05875	COG1960	acyl-CoA dehydrogenase activity
TU94_RS05910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TU94_RS05915	COG0140	phosphoribosyl-ATP diphosphatase activity
TU94_RS05920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TU94_RS05925	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TU94_RS05925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TU94_RS05930	COG3201	nicotinamide mononucleotide transporter
TU94_RS05945	COG1940	carbohydrate kinase activity
TU94_RS05945	COG1846	Transcriptional regulator
TU94_RS05950	COG2223	nitrite transmembrane transporter activity
TU94_RS05955	COG2233	PERMEase
TU94_RS05975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TU94_RS05985	COG0531	amino acid
TU94_RS06000	COG2390	Transcriptional regulator
TU94_RS06005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TU94_RS06015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TU94_RS06030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TU94_RS06040	COG1758	RNA polymerase activity
TU94_RS06045	COG0194	GDP metabolic process
TU94_RS06055	COG0284	orotidine-5'-phosphate decarboxylase activity
TU94_RS06060	COG0167	dihydroorotate dehydrogenase activity
TU94_RS06065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TU94_RS06070	COG0505	Belongs to the CarA family
TU94_RS06080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TU94_RS06085	COG0540	Belongs to the ATCase OTCase family
TU94_RS06090	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
TU94_RS06100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TU94_RS06105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TU94_RS06110	COG0006	proline dipeptidase activity
TU94_RS06120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TU94_RS06125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TU94_RS06130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TU94_RS06135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TU94_RS06140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TU94_RS06145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TU94_RS06150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TU94_RS06170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TU94_RS06185	COG0124	histidyl-tRNA synthetase
TU94_RS06195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TU94_RS06200	COG1196	nuclear chromosome segregation
TU94_RS06205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TU94_RS06210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TU94_RS06215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TU94_RS06220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TU94_RS06230	COG2255	four-way junction helicase activity
TU94_RS06235	COG0632	four-way junction helicase activity
TU94_RS06240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TU94_RS06245	COG0217	transcriptional regulatory protein
TU94_RS06250	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TU94_RS06255	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TU94_RS06265	COG0438	transferase activity, transferring glycosyl groups
TU94_RS06270	COG1560	Kdo2-lipid A biosynthetic process
TU94_RS06275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TU94_RS06295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TU94_RS06305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TU94_RS06330	COG0395	ABC-type sugar transport system, permease component
TU94_RS06335	COG1175	transmembrane transport
TU94_RS06385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TU94_RS06385	COG0512	Glutamine amidotransferase of anthranilate synthase
TU94_RS06440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TU94_RS06440	COG1648	precorrin-2 dehydrogenase activity
TU94_RS06445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TU94_RS06465	COG2011	ABC-type metal ion transport system permease component
TU94_RS06470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TU94_RS06495	COG0584	glycerophosphoryl diester phosphodiesterase
TU94_RS06500	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS06500	COG0204	Acyl-transferase
TU94_RS06505	COG0477	Major facilitator Superfamily
TU94_RS06520	COG0165	Argininosuccinate lyase
TU94_RS06525	COG0137	argininosuccinate synthase activity
TU94_RS06540	COG1438	arginine binding
TU94_RS06545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TU94_RS06550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TU94_RS06555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TU94_RS06560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TU94_RS06580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TU94_RS06585	COG0697	spore germination
TU94_RS06595	COG1649	PFAM Uncharacterised BCR, COG1649
TU94_RS06625	COG0072	phenylalanine-tRNA ligase activity
TU94_RS06625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TU94_RS06630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TU94_RS06635	COG5002	protein histidine kinase activity
TU94_RS06640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TU94_RS06645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TU94_RS06650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TU94_RS06655	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TU94_RS06690	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS06695	COG0174	glutamine synthetase
TU94_RS06700	COG2186	Transcriptional regulator
TU94_RS06705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TU94_RS06730	COG4176	ABC-type proline glycine betaine transport system permease component
TU94_RS06735	COG0517	IMP dehydrogenase activity
TU94_RS06735	COG4175	Glycine betaine
TU94_RS06740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TU94_RS06810	COG0805	protein transport
TU94_RS06815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TU94_RS06835	COG2378	regulation of single-species biofilm formation
TU94_RS06845	COG0545	Peptidyl-prolyl cis-trans isomerase
TU94_RS06850	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TU94_RS06860	COG1609	Transcriptional regulator
TU94_RS06865	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TU94_RS06870	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TU94_RS06880	COG4122	O-methyltransferase activity
TU94_RS06885	COG1222	aaa ATPase
TU94_RS06905	COG0517	IMP dehydrogenase activity
TU94_RS06905	COG1994	Peptidase M50
TU94_RS06915	COG2197	response regulator
TU94_RS06920	COG4166	transmembrane transport
TU94_RS06925	COG0747	negative chemotaxis
TU94_RS06930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TU94_RS06935	COG0646	methionine synthase
TU94_RS06935	COG1410	methionine synthase
TU94_RS06940	COG1414	Transcriptional regulator
TU94_RS06945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TU94_RS06950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TU94_RS06955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TU94_RS06965	COG0215	cysteine-tRNA ligase activity
TU94_RS06985	COG0598	Magnesium transport protein CorA
TU94_RS06990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS06995	COG0667	Aldo Keto reductase
TU94_RS07025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TU94_RS07035	COG3012	SEC-C Motif Domain Protein
TU94_RS07055	COG2186	Transcriptional regulator
TU94_RS07060	COG3265	gluconokinase activity
TU94_RS07085	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
TU94_RS07090	COG2149	membrane
TU94_RS07125	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS07135	COG3876	Protein conserved in bacteria
TU94_RS07175	COG1960	acyl-CoA dehydrogenase activity
TU94_RS07185	COG0640	Transcriptional regulator
TU94_RS07190	COG0477	Major facilitator Superfamily
TU94_RS07215	COG2851	Citrate transporter
TU94_RS07220	COG0243	molybdopterin cofactor binding
TU94_RS07225	COG1309	transcriptional regulator
TU94_RS07235	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
TU94_RS07240	COG2188	Transcriptional regulator
TU94_RS07255	COG2755	lipolytic protein G-D-S-L family
TU94_RS07270	COG1725	Transcriptional regulator
TU94_RS07300	COG0587	DNA-directed DNA polymerase activity
TU94_RS07325	COG1799	cell septum assembly
TU94_RS07330	COG1960	acyl-CoA dehydrogenase activity
TU94_RS07335	COG0477	Major facilitator Superfamily
TU94_RS07345	COG0671	phosphoesterase, PA-phosphatase related
TU94_RS07365	COG1160	GTP binding
TU94_RS07375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TU94_RS07395	COG1187	pseudouridine synthase activity
TU94_RS07400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TU94_RS07405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TU94_RS07420	COG0686	Belongs to the AlaDH PNT family
TU94_RS07430	COG0494	nUDIX hydrolase
TU94_RS07435	COG0504	CTP synthase activity
TU94_RS07440	COG3387	PFAM Glycoside hydrolase 15-related
TU94_RS07445	COG0493	'glutamate synthase
TU94_RS07445	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
TU94_RS07460	COG0438	transferase activity, transferring glycosyl groups
TU94_RS07470	COG0497	DNA recombination
TU94_RS07475	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TU94_RS07495	COG1120	ATPase activity
TU94_RS07500	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TU94_RS07505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TU94_RS07510	COG0647	UMP catabolic process
TU94_RS07545	COG2094	Belongs to the DNA glycosylase MPG family
TU94_RS07555	COG1881	PFAM PEBP family protein
TU94_RS07575	COG1119	ATPase activity
TU94_RS07585	COG2197	response regulator
TU94_RS07600	COG0560	Phosphoserine phosphatase
TU94_RS07600	COG3830	Belongs to the UPF0237 family
TU94_RS07605	COG0588	phosphoglycerate mutase activity
TU94_RS07620	COG2186	Transcriptional regulator
TU94_RS07635	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS07640	COG0312	modulator of DNA gyrase
TU94_RS07650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TU94_RS07655	COG2261	transglycosylase associated protein
TU94_RS07675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TU94_RS07680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TU94_RS07685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TU94_RS07705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TU94_RS07720	COG3387	PFAM Glycoside hydrolase 15-related
TU94_RS07770	COG0488	(ABC) transporter
TU94_RS07790	COG0235	Class ii aldolase
TU94_RS07805	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TU94_RS07810	COG1492	cobalamin metabolic process
TU94_RS07825	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TU94_RS07830	COG1797	cobyrinic acid a,c-diamide synthase activity
TU94_RS07860	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
TU94_RS07880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TU94_RS07885	COG0456	acetyltransferase
TU94_RS07890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TU94_RS07895	COG1917	Cupin 2, conserved barrel domain protein
TU94_RS07900	COG5285	phytanoyl-CoA dioxygenase
TU94_RS07905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TU94_RS07915	COG4977	sequence-specific DNA binding
TU94_RS07920	COG0477	Major facilitator Superfamily
TU94_RS07930	COG1414	Transcriptional regulator
TU94_RS07945	COG1595	DNA-templated transcription, initiation
TU94_RS07960	COG4677	pectinesterase activity
TU94_RS07965	COG3866	Pectate lyase
TU94_RS07970	COG2755	lipolytic protein G-D-S-L family
TU94_RS07980	COG4677	pectinesterase activity
TU94_RS08000	COG3866	Pectate lyase
TU94_RS08005	COG0395	ABC-type sugar transport system, permease component
TU94_RS08010	COG1175	transmembrane transport
TU94_RS08020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TU94_RS08025	COG1802	Transcriptional regulator
TU94_RS08035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TU94_RS08040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TU94_RS08050	COG1309	transcriptional regulator
TU94_RS08095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TU94_RS08105	COG2171	N-acyltransferase activity
TU94_RS08110	COG3226	Transcriptional regulator
TU94_RS08115	COG2076	Multidrug Resistance protein
TU94_RS08120	COG2151	metal-sulfur cluster biosynthetic enzyme
TU94_RS08125	COG0822	iron-sulfur transferase activity
TU94_RS08130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TU94_RS08135	COG0396	ATPase activity
TU94_RS08145	COG0719	Fe-S assembly protein
TU94_RS08160	COG1131	(ABC) transporter
TU94_RS08170	COG1612	heme a metabolic process
TU94_RS08190	COG0109	protoheme IX farnesyltransferase activity
TU94_RS08200	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TU94_RS08215	COG0363	glucosamine-6-phosphate deaminase activity
TU94_RS08225	COG3631	Ketosteroid isomerase-related protein
TU94_RS08230	COG0702	epimerase
TU94_RS08235	COG0166	Belongs to the GPI family
TU94_RS08255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TU94_RS08260	COG0149	triose-phosphate isomerase activity
TU94_RS08265	COG0126	phosphoglycerate kinase activity
TU94_RS08270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TU94_RS08280	COG1481	regulation of sporulation
TU94_RS08285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TU94_RS08290	COG1660	Displays ATPase and GTPase activities
TU94_RS08295	COG0322	excinuclease ABC activity
TU94_RS08320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TU94_RS08335	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TU94_RS08340	COG1619	proteins homologs of microcin C7 resistance protein MccF
TU94_RS08345	COG0477	Major facilitator Superfamily
TU94_RS08350	COG0387	Pfam Sodium calcium exchanger
TU94_RS08370	COG0556	nucleotide-excision repair
TU94_RS08380	COG0584	glycerophosphoryl diester phosphodiesterase
TU94_RS08385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TU94_RS08390	COG2313	pseudouridylate synthase activity
TU94_RS08395	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TU94_RS08395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TU94_RS08400	COG2226	methyltransferase
TU94_RS08405	COG0598	Magnesium transport protein CorA
TU94_RS08415	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TU94_RS08420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TU94_RS08445	COG1132	(ABC) transporter
TU94_RS08460	COG0402	S-adenosylhomocysteine deaminase activity
TU94_RS08530	COG0237	dephospho-CoA kinase activity
TU94_RS08540	COG0539	negative regulation of cytoplasmic translation
TU94_RS08550	COG1643	Atp-dependent helicase
TU94_RS08580	COG2050	protein possibly involved in aromatic compounds catabolism
TU94_RS08630	COG0737	Belongs to the 5'-nucleotidase family
TU94_RS08645	COG0596	Alpha beta hydrolase
TU94_RS08650	COG2208	phosphoserine phosphatase activity
TU94_RS08650	COG2770	Histidine kinase
TU94_RS08660	COG1605	Chorismate mutase
TU94_RS08660	COG0287	Prephenate dehydrogenase
TU94_RS08680	COG0069	glutamate synthase activity
TU94_RS08680	COG0070	glutamate synthase
TU94_RS08680	COG0067	glutamate synthase
TU94_RS08710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TU94_RS08715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TU94_RS08720	COG2301	Belongs to the HpcH HpaI aldolase family
TU94_RS08725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TU94_RS08735	COG0159	tryptophan synthase activity
TU94_RS08740	COG0133	tryptophan synthase activity
TU94_RS08745	COG0134	indole-3-glycerol-phosphate synthase activity
TU94_RS08770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TU94_RS08780	COG0107	imidazoleglycerol-phosphate synthase activity
TU94_RS08785	COG0251	oxidation-reduction process
TU94_RS08790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TU94_RS08795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TU94_RS08805	COG0131	Imidazoleglycerol-phosphate dehydratase
TU94_RS08810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TU94_RS08815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TU94_RS08835	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TU94_RS08865	COG1432	Conserved Protein
TU94_RS08870	COG0587	DNA-directed DNA polymerase activity
TU94_RS08905	COG0025	NhaP-type Na H and K H
TU94_RS08920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TU94_RS08930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TU94_RS08935	COG3599	regulation of cell shape
TU94_RS08945	COG1799	cell septum assembly
TU94_RS08955	COG1496	oxidoreductase activity
TU94_RS08960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TU94_RS08965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
TU94_RS08970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TU94_RS08980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TU94_RS08985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TU94_RS08995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TU94_RS09000	COG0768	penicillin binding
TU94_RS09010	COG0275	rRNA processing
TU94_RS09020	COG0714	Associated with various cellular activities
TU94_RS09040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TU94_RS09060	COG1309	transcriptional regulator
TU94_RS09080	COG0352	thiamine-phosphate diphosphorylase activity
TU94_RS09100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TU94_RS09100	COG2022	thiamine diphosphate biosynthetic process
TU94_RS09110	COG2022	thiamine diphosphate biosynthetic process
TU94_RS09115	COG2815	serine threonine protein kinase
TU94_RS09115	COG0515	serine threonine protein kinase
TU94_RS09120	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TU94_RS09130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TU94_RS09135	COG2193	ferroxidase activity
TU94_RS09145	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
TU94_RS09155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TU94_RS09160	COG2197	response regulator
TU94_RS09165	COG4585	Histidine kinase
TU94_RS09190	COG1940	carbohydrate kinase activity
TU94_RS09200	COG0003	Pfam Anion-transporting ATPase
TU94_RS09270	COG2205	protein histidine kinase activity
TU94_RS09275	COG0745	RESPONSE REGULATOR receiver
TU94_RS09285	COG1929	Belongs to the glycerate kinase type-1 family
TU94_RS09290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TU94_RS09295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TU94_RS09300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TU94_RS09305	COG0723	plastoquinol--plastocyanin reductase activity
TU94_RS09310	COG2010	Cytochrome c
TU94_RS09315	COG1845	cytochrome c oxidase, subunit III
TU94_RS09325	COG1376	ErfK ybiS ycfS ynhG family protein
TU94_RS09335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TU94_RS09340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TU94_RS09350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TU94_RS09370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TU94_RS09375	COG0515	serine threonine protein kinase
TU94_RS09375	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TU94_RS09380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TU94_RS09385	COG2197	response regulator
TU94_RS09390	COG4585	Histidine kinase
TU94_RS09415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TU94_RS09435	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TU94_RS09450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TU94_RS09455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TU94_RS09460	COG0508	dehydrogenase complex catalyzes the overall conversion of
TU94_RS09470	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
TU94_RS09490	COG0456	acetyltransferase
TU94_RS09495	COG1090	epimerase
TU94_RS09510	COG0321	lipoyl(octanoyl) transferase activity
TU94_RS09515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TU94_RS09535	COG0174	glutamine synthetase
TU94_RS09560	COG0745	RESPONSE REGULATOR receiver
TU94_RS09580	COG1309	transcriptional regulator
TU94_RS09600	COG0366	Alpha amylase catalytic
TU94_RS09605	COG3833	ABC-type maltose transport systems, permease component
TU94_RS09610	COG1175	transmembrane transport
TU94_RS09615	COG2182	Extracellular solute-binding protein
TU94_RS09620	COG1609	Transcriptional regulator
TU94_RS09630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
TU94_RS09640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TU94_RS09640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TU94_RS09660	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
TU94_RS09690	COG0531	amino acid
TU94_RS09690	COG1674	ftsk spoiiie
TU94_RS09755	COG2814	Major facilitator Superfamily
TU94_RS09765	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TU94_RS09785	COG1994	Peptidase M50
TU94_RS09845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS09850	COG2814	Major facilitator Superfamily
TU94_RS09860	COG3540	Alkaline phosphatase
TU94_RS09870	COG0667	Aldo Keto reductase
TU94_RS09880	COG2259	Doxx family
TU94_RS09900	COG3022	response to hydroperoxide
TU94_RS09905	COG0800	Aldolase
TU94_RS09920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TU94_RS09930	COG2030	dehydratase
TU94_RS09940	COG0477	Major facilitator Superfamily
TU94_RS09950	COG0860	N-Acetylmuramoyl-L-alanine amidase
TU94_RS09975	COG0438	transferase activity, transferring glycosyl groups
TU94_RS09985	COG1657	PFAM Prenyltransferase squalene oxidase
TU94_RS10000	COG3845	ABC transporter
TU94_RS10030	COG4122	O-methyltransferase activity
TU94_RS10065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TU94_RS10105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TU94_RS10150	COG4585	Histidine kinase
TU94_RS10155	COG0586	Pfam SNARE associated Golgi protein
TU94_RS10165	COG1358	cellular component organization or biogenesis
TU94_RS10210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
TU94_RS10215	COG0477	Major facilitator Superfamily
TU94_RS10220	COG1309	transcriptional regulator
TU94_RS10235	COG0667	Aldo Keto reductase
TU94_RS10240	COG0789	Transcriptional regulator
TU94_RS10270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TU94_RS10275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TU94_RS10280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TU94_RS10315	COG1764	response to oxidative stress
TU94_RS10320	COG2130	NADP-dependent
TU94_RS10365	COG4214	carbohydrate transport
TU94_RS10375	COG3940	Belongs to the glycosyl hydrolase 43 family
TU94_RS10380	COG3507	Belongs to the glycosyl hydrolase 43 family
TU94_RS10425	COG1280	lysine exporter protein (LysE YggA)
TU94_RS10435	COG3507	Belongs to the glycosyl hydrolase 43 family
TU94_RS10440	COG0395	ABC-type sugar transport system, permease component
TU94_RS10445	COG1175	transmembrane transport
TU94_RS10485	COG3386	PFAM SMP-30 Gluconolaconase
TU94_RS10490	COG1414	Transcriptional regulator
TU94_RS10500	COG2186	Transcriptional regulator
TU94_RS10505	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS10510	COG0825	malonyl-CoA metabolic process
TU94_RS10510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TU94_RS10515	COG1404	Belongs to the peptidase S8 family
TU94_RS10520	COG1077	Cell shape determining protein MreB Mrl
TU94_RS10590	COG1070	Carbohydrate kinase
TU94_RS10605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TU94_RS10610	COG0358	DNA primase activity
TU94_RS10620	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TU94_RS10635	COG0243	molybdopterin cofactor binding
TU94_RS10645	COG0431	NADPH-dependent FMN reductase
TU94_RS10660	COG1733	regulation of RNA biosynthetic process
TU94_RS10675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TU94_RS10680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TU94_RS10680	COG2146	nitrite reductase [NAD(P)H] activity
TU94_RS10690	COG1309	transcriptional regulator
TU94_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS10735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TU94_RS10735	COG0574	Belongs to the PEP-utilizing enzyme family
TU94_RS10740	COG1940	carbohydrate kinase activity
TU94_RS10740	COG1846	Transcriptional regulator
TU94_RS10760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TU94_RS10775	COG2267	carboxylic ester hydrolase activity
TU94_RS10780	COG0477	Major facilitator Superfamily
TU94_RS10810	COG0423	glycine-tRNA ligase activity
TU94_RS10815	COG0803	Belongs to the bacterial solute-binding protein 9 family
TU94_RS10815	COG3443	Belongs to the bacterial solute-binding protein 9 family
TU94_RS10820	COG1121	(ABC) transporter
TU94_RS10825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TU94_RS10840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TU94_RS10845	COG1381	Involved in DNA repair and RecF pathway recombination
TU94_RS10865	COG1959	2 iron, 2 sulfur cluster binding
TU94_RS10885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TU94_RS10900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TU94_RS10920	COG2315	Protein conserved in bacteria
TU94_RS10930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TU94_RS10945	COG4948	Mandelate Racemase Muconate Lactonizing
TU94_RS10955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TU94_RS10960	COG1234	tRNA 3'-trailer cleavage
TU94_RS10965	COG0537	adenosine 5'-monophosphoramidase activity
TU94_RS10970	COG0793	Belongs to the peptidase S41A family
TU94_RS10970	COG4946	Tricorn protease homolog
TU94_RS10985	COG0484	heat shock protein binding
TU94_RS10990	COG1420	regulation of RNA biosynthetic process
TU94_RS11015	COG0481	GTPase activity
TU94_RS11020	COG0268	Binds directly to 16S ribosomal RNA
TU94_RS11040	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TU94_RS11070	COG1234	tRNA 3'-trailer cleavage
TU94_RS11080	COG1307	EDD domain protein, DegV family
TU94_RS11090	COG0495	leucyl-tRNA aminoacylation
TU94_RS11110	COG0406	alpha-ribazole phosphatase activity
TU94_RS11115	COG0799	negative regulation of ribosome biogenesis
TU94_RS11125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TU94_RS11140	COG0501	Belongs to the peptidase M48B family
TU94_RS11155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TU94_RS11165	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TU94_RS11175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TU94_RS11180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TU94_RS11185	COG0438	transferase activity, transferring glycosyl groups
TU94_RS11190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TU94_RS11195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TU94_RS11200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TU94_RS11205	COG0371	Dehydrogenase
TU94_RS11215	COG1530	ribonuclease E activity
TU94_RS11235	COG0772	Belongs to the SEDS family
TU94_RS11255	COG1077	Cell shape determining protein MreB Mrl
TU94_RS11260	COG0105	UTP biosynthetic process
TU94_RS11270	COG0285	dihydrofolate synthase activity
TU94_RS11275	COG0525	valine-tRNA ligase activity
TU94_RS11285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TU94_RS11290	COG0740	serine-type endopeptidase activity
TU94_RS11295	COG0740	serine-type endopeptidase activity
TU94_RS11300	COG0544	peptidyl-prolyl cis-trans isomerase activity
TU94_RS11320	COG3594	Acyltransferase
TU94_RS11335	COG4552	Acetyltransferase involved in intracellular survival and related
TU94_RS11350	COG1113	amino acid transport
TU94_RS11360	COG1113	amino acid transport
TU94_RS11365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TU94_RS11375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TU94_RS11440	COG2814	Major facilitator Superfamily
TU94_RS11450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TU94_RS11465	COG0667	Aldo Keto reductase
TU94_RS11495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TU94_RS11500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS11510	COG0022	dehydrogenase e1 component
TU94_RS11515	COG0508	dehydrogenase complex catalyzes the overall conversion of
TU94_RS11520	COG2814	Major facilitator Superfamily
TU94_RS11550	COG0697	spore germination
TU94_RS11555	COG1846	Transcriptional regulator
TU94_RS11560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TU94_RS11585	COG3525	Glycosyl hydrolase, family 20, catalytic domain
TU94_RS11585	COG3291	Pkd domain containing protein
TU94_RS11590	COG1595	DNA-templated transcription, initiation
TU94_RS11600	COG1131	(ABC) transporter
TU94_RS11625	COG0668	transmembrane transport
TU94_RS11635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TU94_RS11665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TU94_RS11670	COG2346	COG2346, Truncated hemoglobins
TU94_RS11695	COG0629	single-stranded DNA binding
TU94_RS11700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TU94_RS11745	COG2304	oxidoreductase activity
TU94_RS11770	COG0297	glycogen (starch) synthase activity
TU94_RS11775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TU94_RS11785	COG0728	peptidoglycan biosynthetic process
TU94_RS11795	COG0438	transferase activity, transferring glycosyl groups
TU94_RS11840	COG1131	(ABC) transporter
TU94_RS11855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TU94_RS11885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TU94_RS11900	COG3386	PFAM SMP-30 Gluconolaconase
TU94_RS11925	COG1129	ABC transporter
TU94_RS11935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TU94_RS11940	COG1869	D-ribose catabolic process
TU94_RS11955	COG0673	inositol 2-dehydrogenase activity
TU94_RS11960	COG1609	Transcriptional regulator
TU94_RS11965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TU94_RS11985	COG2197	response regulator
TU94_RS11990	COG4585	Histidine kinase
TU94_RS12015	COG1472	Belongs to the glycosyl hydrolase 3 family
TU94_RS12045	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TU94_RS12055	COG0028	Belongs to the TPP enzyme family
TU94_RS12065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TU94_RS12090	COG1946	Acyl-CoA thioesterase
TU94_RS12100	COG1309	transcriptional regulator
TU94_RS12105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TU94_RS12120	COG1960	acyl-CoA dehydrogenase activity
TU94_RS12140	COG3486	L-lysine 6-monooxygenase (NADPH) activity
TU94_RS12170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TU94_RS12175	COG0589	response to stress
TU94_RS12185	COG4977	sequence-specific DNA binding
TU94_RS12190	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
TU94_RS12230	COG0395	ABC-type sugar transport system, permease component
TU94_RS12260	COG0745	RESPONSE REGULATOR receiver
TU94_RS12335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS12345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TU94_RS12350	COG0765	amino acid transport
TU94_RS12355	COG0765	amino acid transport
TU94_RS12360	COG1126	abc transporter atp-binding protein
TU94_RS12375	COG3397	chitin binding
TU94_RS12415	COG0673	inositol 2-dehydrogenase activity
TU94_RS12420	COG4702	Belongs to the UPF0303 family
TU94_RS12435	COG0706	membrane insertase activity
TU94_RS12480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TU94_RS12525	COG2814	Major facilitator Superfamily
TU94_RS12530	COG2733	membrane
TU94_RS12560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TU94_RS12590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TU94_RS12600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TU94_RS12605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TU94_RS12610	COG1263	PTS System
TU94_RS12615	COG1263	PTS System
TU94_RS12620	COG1234	tRNA 3'-trailer cleavage
TU94_RS12645	COG1113	amino acid transport
TU94_RS12655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
TU94_RS12665	COG1335	isochorismatase
TU94_RS12700	COG0277	FAD linked oxidase domain protein
TU94_RS12710	COG3185	4-Hydroxyphenylpyruvate dioxygenase
TU94_RS12720	COG1174	glycine betaine transport
TU94_RS12730	COG1174	glycine betaine transport
TU94_RS12790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
TU94_RS12795	COG0395	ABC-type sugar transport system, permease component
TU94_RS12815	COG1678	Uncharacterized ACR, COG1678
TU94_RS12820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TU94_RS12825	COG0776	regulation of translation
TU94_RS12835	COG3973	AAA domain
TU94_RS12850	COG2223	nitrite transmembrane transporter activity
TU94_RS12870	COG0583	DNA-binding transcription factor activity
TU94_RS12880	COG1609	Transcriptional regulator
TU94_RS12890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TU94_RS12895	COG0793	Belongs to the peptidase S41A family
TU94_RS12905	COG2884	Cell division ATP-binding protein ftsE
TU94_RS12920	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TU94_RS12925	COG0515	serine threonine protein kinase
TU94_RS12930	COG0515	serine threonine protein kinase
TU94_RS12935	COG1674	ftsk spoiiie
TU94_RS12945	COG1175	transmembrane transport
TU94_RS12950	COG0395	ABC-type sugar transport system, permease component
TU94_RS12960	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TU94_RS12980	COG1764	response to oxidative stress
TU94_RS12985	COG1846	Transcriptional regulator
TU94_RS12990	COG0463	Glycosyl transferase, family 2
TU94_RS13005	COG1134	teichoic acid transport
TU94_RS13005	COG1388	LysM domain
TU94_RS13010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TU94_RS13015	COG1215	transferase activity, transferring glycosyl groups
TU94_RS13025	COG2902	Dehydrogenase
TU94_RS13045	COG0653	protein targeting
TU94_RS13055	COG3214	Protein conserved in bacteria
TU94_RS13060	COG2197	response regulator
TU94_RS13065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TU94_RS13075	COG0823	Involved in the tonB-independent uptake of proteins
TU94_RS13080	COG5002	protein histidine kinase activity
TU94_RS13085	COG0745	RESPONSE REGULATOR receiver
TU94_RS13100	COG2188	Transcriptional regulator
TU94_RS13105	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TU94_RS13125	COG0714	Associated with various cellular activities
TU94_RS13165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TU94_RS13175	COG1482	cell wall glycoprotein biosynthetic process
TU94_RS13185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TU94_RS13190	COG1620	l-lactate permease
TU94_RS13225	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TU94_RS13230	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
TU94_RS13230	COG0778	Nitroreductase
TU94_RS13255	COG1316	TRANSCRIPTIONal
TU94_RS13260	COG1316	TRANSCRIPTIONal
TU94_RS13265	COG1316	TRANSCRIPTIONal
TU94_RS13280	COG1316	TRANSCRIPTIONal
TU94_RS13290	COG1316	TRANSCRIPTIONal
TU94_RS13295	COG1607	acyl-coa hydrolase
TU94_RS13320	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TU94_RS13345	COG0789	Transcriptional regulator
TU94_RS13350	COG1902	pentaerythritol trinitrate reductase activity
TU94_RS13375	COG2205	protein histidine kinase activity
TU94_RS13380	COG0745	RESPONSE REGULATOR receiver
TU94_RS13385	COG3104	oligopeptide transport
TU94_RS13395	COG1366	Belongs to the anti-sigma-factor antagonist family
TU94_RS13400	COG1191	sigma factor activity
TU94_RS13405	COG1228	amidohydrolase
TU94_RS13420	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
TU94_RS13450	COG2755	lipolytic protein G-D-S-L family
TU94_RS13455	COG0183	Belongs to the thiolase family
TU94_RS13490	COG1136	(ABC) transporter
TU94_RS13495	COG0577	efflux transmembrane transporter activity
TU94_RS13500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TU94_RS13505	COG1252	NADH dehydrogenase
TU94_RS13530	COG0148	phosphopyruvate hydratase activity
TU94_RS13540	COG1652	LysM domain
TU94_RS13560	COG2815	serine threonine protein kinase
TU94_RS13560	COG0515	serine threonine protein kinase
TU94_RS13595	COG0577	efflux transmembrane transporter activity
TU94_RS13600	COG1136	(ABC) transporter
TU94_RS13605	COG2814	Major facilitator Superfamily
TU94_RS13635	COG4585	Histidine kinase
TU94_RS13650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TU94_RS13655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TU94_RS13660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TU94_RS13665	COG0193	aminoacyl-tRNA hydrolase activity
TU94_RS13680	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
TU94_RS13695	COG4106	trans-aconitate 2-methyltransferase activity
TU94_RS13705	COG2197	response regulator
TU94_RS13715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TU94_RS13745	COG0488	(ABC) transporter
TU94_RS13750	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TU94_RS13755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TU94_RS13765	COG0084	hydrolase, TatD family'
TU94_RS13800	COG0310	cobalt ion transport
TU94_RS13810	COG1122	ATPase activity
TU94_RS13815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS13835	COG2409	Drug exporters of the RND superfamily
TU94_RS13845	COG4946	Tricorn protease homolog
TU94_RS13845	COG0793	Belongs to the peptidase S41A family
TU94_RS13855	COG2267	carboxylic ester hydrolase activity
TU94_RS13860	COG2072	flavoprotein involved in K transport
TU94_RS13875	COG0454	-acetyltransferase
TU94_RS13880	COG2197	response regulator
TU94_RS13890	COG1136	(ABC) transporter
TU94_RS13890	COG0577	efflux transmembrane transporter activity
TU94_RS13895	COG0577	efflux transmembrane transporter activity
TU94_RS13910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TU94_RS13915	COG0521	Mo-molybdopterin cofactor biosynthetic process
TU94_RS13915	COG0315	cyclic pyranopterin monophosphate synthase activity
TU94_RS13920	COG0315	cyclic pyranopterin monophosphate synthase activity
TU94_RS13930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TU94_RS13935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TU94_RS13945	COG3263	regulation of cellular component size
TU94_RS13950	COG0477	Major facilitator Superfamily
TU94_RS13955	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TU94_RS13965	COG1970	mechanosensitive ion channel activity
TU94_RS13975	COG1376	ErfK ybiS ycfS ynhG family protein
TU94_RS13990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TU94_RS13990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TU94_RS13990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TU94_RS14000	COG1349	DNA-binding transcription factor activity
TU94_RS14005	COG0477	Major facilitator Superfamily
TU94_RS14020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TU94_RS14025	COG3384	dioxygenase
TU94_RS14030	COG1846	Transcriptional regulator
TU94_RS14050	COG1414	Transcriptional regulator
TU94_RS14100	COG1487	ribonuclease activity
TU94_RS14120	COG2318	DinB family
TU94_RS14150	COG1278	Cold shock
TU94_RS14155	COG0513	Belongs to the DEAD box helicase family
TU94_RS14225	COG0386	Belongs to the glutathione peroxidase family
TU94_RS14245	COG1686	Belongs to the peptidase S11 family
TU94_RS14260	COG0110	maltose O-acetyltransferase activity
TU94_RS14315	COG2365	Tyrosine phosphatase family
TU94_RS14330	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TU94_RS14350	COG3903	Transcriptional regulator
TU94_RS14350	COG3629	intracellular signal transduction
TU94_RS14365	COG0515	serine threonine protein kinase
TU94_RS14365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TU94_RS14375	COG1309	transcriptional regulator
TU94_RS14380	COG1522	sequence-specific DNA binding
TU94_RS14385	COG1280	lysine exporter protein (LysE YggA)
TU94_RS14395	COG0259	pyridoxamine-phosphate oxidase activity
TU94_RS14415	COG1366	Belongs to the anti-sigma-factor antagonist family
TU94_RS14480	COG4821	SIS domain
TU94_RS14495	COG0259	pyridoxamine-phosphate oxidase activity
TU94_RS14575	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS14580	COG1959	2 iron, 2 sulfur cluster binding
TU94_RS14585	COG0247	lactate metabolic process
TU94_RS14585	COG0277	FAD linked oxidase domain protein
TU94_RS14595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TU94_RS14615	COG0180	Tryptophanyl-tRNA synthetase
TU94_RS14620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TU94_RS14630	COG4991	sh3 domain protein
TU94_RS14640	COG0129	dihydroxy-acid dehydratase activity
TU94_RS14645	COG1082	Xylose isomerase domain protein TIM barrel
TU94_RS14650	COG0248	Ppx GppA phosphatase
TU94_RS14670	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
TU94_RS14685	COG2197	response regulator
TU94_RS14690	COG4585	Histidine kinase
TU94_RS14695	COG1194	a g-specific adenine glycosylase
TU94_RS14700	COG1595	DNA-templated transcription, initiation
TU94_RS14710	COG0745	RESPONSE REGULATOR receiver
TU94_RS14715	COG2205	protein histidine kinase activity
TU94_RS14720	COG0739	heme binding
TU94_RS14750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TU94_RS14770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TU94_RS14780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TU94_RS14785	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TU94_RS14810	COG2197	response regulator
TU94_RS14825	COG0649	NAD binding
TU94_RS14850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TU94_RS14850	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
TU94_RS14865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TU94_RS14880	COG0302	gtp cyclohydrolase
TU94_RS14895	COG0037	tRNA processing
TU94_RS14905	COG2027	D-alanyl-D-alanine carboxypeptidase
TU94_RS14910	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TU94_RS14920	COG0586	Pfam SNARE associated Golgi protein
TU94_RS14925	COG0789	Transcriptional regulator
TU94_RS14935	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS14955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TU94_RS14965	COG0254	rRNA binding
TU94_RS14970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TU94_RS14975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TU94_RS14980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TU94_RS15005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TU94_RS15005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TU94_RS15010	COG3903	Transcriptional regulator
TU94_RS15010	COG3629	intracellular signal transduction
TU94_RS15035	COG1434	Gram-negative-bacterium-type cell wall biogenesis
TU94_RS15040	COG2188	Transcriptional regulator
TU94_RS15070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TU94_RS15075	COG1754	DNA topoisomerase type I activity
TU94_RS15075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TU94_RS15095	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TU94_RS15100	COG2172	sigma factor antagonist activity
TU94_RS15105	COG1366	Belongs to the anti-sigma-factor antagonist family
TU94_RS15110	COG1205	dead DEAH box helicase
TU94_RS15110	COG1111	helicase
TU94_RS15170	COG0659	secondary active sulfate transmembrane transporter activity
TU94_RS15175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TU94_RS15180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TU94_RS15190	COG2267	carboxylic ester hydrolase activity
TU94_RS15215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TU94_RS15225	COG0596	Alpha beta hydrolase
TU94_RS15240	COG0003	Pfam Anion-transporting ATPase
TU94_RS15250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TU94_RS15260	COG1408	metallophosphoesterase
TU94_RS15310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS15365	COG0659	secondary active sulfate transmembrane transporter activity
TU94_RS15370	COG0659	secondary active sulfate transmembrane transporter activity
TU94_RS15400	COG1595	DNA-templated transcription, initiation
TU94_RS15425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TU94_RS15430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TU94_RS15445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TU94_RS15450	COG1802	Transcriptional regulator
TU94_RS15500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TU94_RS15515	COG1131	(ABC) transporter
TU94_RS15520	COG3559	Exporter of polyketide antibiotics
TU94_RS15535	COG2197	response regulator
TU94_RS15540	COG4585	Histidine kinase
TU94_RS15555	COG3844	kynureninase activity
TU94_RS15570	COG0191	fructose-bisphosphate aldolase activity
TU94_RS15575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TU94_RS15590	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TU94_RS15615	COG0542	response to heat
TU94_RS15640	COG4213	ABC transporter substrate-binding protein
TU94_RS15645	COG5297	Belongs to the glycosyl hydrolase family 6
TU94_RS15645	COG4733	cellulase activity
TU94_RS15650	COG0789	Transcriptional regulator
TU94_RS15655	COG0484	heat shock protein binding
TU94_RS15660	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TU94_RS15665	COG0443	Heat shock 70 kDa protein
TU94_RS15670	COG0247	lactate metabolic process
TU94_RS15670	COG2181	nitrate reductase activity
TU94_RS15680	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
TU94_RS15685	COG0717	Belongs to the dCTP deaminase family
TU94_RS15710	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS15755	COG3903	Transcriptional regulator
TU94_RS15755	COG3629	intracellular signal transduction
TU94_RS15795	COG4977	sequence-specific DNA binding
TU94_RS15820	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS15825	COG0667	Aldo Keto reductase
TU94_RS15830	COG0667	Aldo Keto reductase
TU94_RS15885	COG0366	Alpha amylase catalytic
TU94_RS15945	COG2188	Transcriptional regulator
TU94_RS15960	COG1653	transport
TU94_RS16015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TU94_RS16025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TU94_RS16040	COG1741	Belongs to the pirin family
TU94_RS16050	COG1960	acyl-CoA dehydrogenase activity
TU94_RS16055	COG1362	aminopeptidase activity
TU94_RS16125	COG2186	Transcriptional regulator
TU94_RS16135	COG0508	dehydrogenase complex catalyzes the overall conversion of
TU94_RS16140	COG0022	dehydrogenase e1 component
TU94_RS16160	COG0515	serine threonine protein kinase
TU94_RS16175	COG0604	alcohol dehydrogenase
TU94_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS16175	COG3321	synthase
TU94_RS16220	COG1522	sequence-specific DNA binding
TU94_RS16225	COG1309	transcriptional regulator
TU94_RS16230	COG1250	3-hydroxyacyl-CoA dehydrogenase
TU94_RS16255	COG3396	Phenylacetate-CoA oxygenase
TU94_RS16260	COG3460	Phenylacetate-CoA oxygenase
TU94_RS16265	COG3396	Phenylacetate-CoA oxygenase
TU94_RS16270	COG2151	metal-sulfur cluster biosynthetic enzyme
TU94_RS16275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TU94_RS16280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TU94_RS16305	COG1716	ATPase activity
TU94_RS16310	COG1716	ATPase activity
TU94_RS16325	COG0768	penicillin binding
TU94_RS16330	COG0515	serine threonine protein kinase
TU94_RS16335	COG3764	Sortase (surface protein transpeptidase)
TU94_RS16340	COG3764	Sortase (surface protein transpeptidase)
TU94_RS16365	COG0705	Rhomboid family
TU94_RS16390	COG0515	serine threonine protein kinase
TU94_RS16430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TU94_RS16435	COG0187	DNA topoisomerase II activity
TU94_RS16440	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
TU94_RS16445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TU94_RS16450	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
TU94_RS16455	COG0592	DNA-directed DNA polymerase activity
TU94_RS16470	COG0706	membrane insertase activity
TU94_RS16480	COG0357	Ribosomal RNA small subunit methyltransferase G
TU94_RS16485	COG1192	Involved in chromosome partitioning
TU94_RS16500	COG3118	belongs to the thioredoxin family
TU94_RS16505	COG0492	ferredoxin-NADP+ reductase activity
TU94_RS16515	COG1595	DNA-templated transcription, initiation
TU94_RS16520	COG2815	serine threonine protein kinase
TU94_RS16520	COG0515	serine threonine protein kinase
TU94_RS16535	COG0617	tRNA 3'-terminal CCA addition
TU94_RS16550	COG1260	myo-inositol-1-phosphate synthase
TU94_RS16560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TU94_RS16585	COG0360	Binds together with S18 to 16S ribosomal RNA
TU94_RS16590	COG0629	single-stranded DNA binding
TU94_RS16595	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TU94_RS16600	COG0359	binds to the 23S rRNA
TU94_RS16605	COG0534	Mate efflux family protein
TU94_RS16610	COG0305	Participates in initiation and elongation during chromosome replication
TU94_RS16615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TU94_RS16635	COG2814	Major facilitator Superfamily
TU94_RS16660	COG0626	cystathionine gamma-synthase activity
TU94_RS16665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TU94_RS16670	COG1950	PFAM Membrane protein of
TU94_RS16675	COG0662	Cupin 2, conserved barrel domain protein
TU94_RS16700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TU94_RS16715	COG1609	Transcriptional regulator
TU94_RS16720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TU94_RS16730	COG1271	oxidase subunit
TU94_RS16735	COG1294	oxidase, subunit
TU94_RS16740	COG4988	ABC transporter
TU94_RS16750	COG0739	heme binding
TU94_RS16750	COG1196	nuclear chromosome segregation
TU94_RS16750	COG0741	lytic transglycosylase activity
TU94_RS16755	COG0561	phosphatase activity
TU94_RS16770	COG1131	(ABC) transporter
TU94_RS16790	COG0561	phosphatase activity
TU94_RS16795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TU94_RS16800	COG0077	Prephenate dehydratase
TU94_RS16805	COG2837	iron assimilation
TU94_RS16810	COG1276	copper resistance
TU94_RS16820	COG1999	signal sequence binding
TU94_RS16840	COG0006	proline dipeptidase activity
TU94_RS16860	COG0653	protein targeting
TU94_RS16875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TU94_RS16935	COG1595	DNA-templated transcription, initiation
TU94_RS16940	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS16945	COG2814	Major facilitator Superfamily
TU94_RS16950	COG1309	transcriptional regulator
TU94_RS16955	COG0784	Response regulator, receiver
TU94_RS17010	COG1733	regulation of RNA biosynthetic process
TU94_RS17040	COG0745	RESPONSE REGULATOR receiver
TU94_RS17045	COG2205	protein histidine kinase activity
TU94_RS17055	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TU94_RS17060	COG0477	Major facilitator Superfamily
TU94_RS17070	COG3467	pyridoxamine 5'-phosphate
TU94_RS17090	COG2353	YceI-like domain
TU94_RS17110	COG1191	sigma factor activity
TU94_RS17115	COG1191	sigma factor activity
TU94_RS17150	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TU94_RS17165	COG0433	COG0433 Predicted ATPase
TU94_RS17210	COG0584	glycerophosphoryl diester phosphodiesterase
TU94_RS17230	COG0151	Belongs to the GarS family
TU94_RS17245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TU94_RS17255	COG2197	response regulator
TU94_RS17290	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TU94_RS17295	COG0047	phosphoribosylformylglycinamidine synthase activity
TU94_RS17300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TU94_RS17320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TU94_RS17330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TU94_RS17355	COG1643	Atp-dependent helicase
TU94_RS17440	COG0582	viral genome integration into host DNA
TU94_RS17475	COG0513	Belongs to the DEAD box helicase family
TU94_RS17490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TU94_RS17490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TU94_RS17510	COG0667	Aldo Keto reductase
TU94_RS17520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TU94_RS17530	COG0579	oxidoreductase
TU94_RS17545	COG1470	cell adhesion involved in biofilm formation
TU94_RS17545	COG0366	Alpha amylase catalytic
TU94_RS17555	COG1252	NADH dehydrogenase
TU94_RS17590	COG2197	response regulator
TU94_RS17595	COG4585	Histidine kinase
TU94_RS17635	COG0739	heme binding
TU94_RS17635	COG0741	lytic transglycosylase activity
TU94_RS17635	COG1196	nuclear chromosome segregation
TU94_RS17640	COG0671	phosphoesterase, PA-phosphatase related
TU94_RS17650	COG1937	Protein conserved in bacteria
TU94_RS17660	COG0306	phosphate transporter
TU94_RS17665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TU94_RS17690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TU94_RS17720	COG0456	acetyltransferase
TU94_RS17725	COG0737	Belongs to the 5'-nucleotidase family
TU94_RS17775	COG0745	RESPONSE REGULATOR receiver
TU94_RS17780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TU94_RS17785	COG1609	Transcriptional regulator
TU94_RS17790	COG0745	RESPONSE REGULATOR receiver
TU94_RS17815	COG2897	thiosulfate sulfurtransferase activity
TU94_RS17840	COG3485	protocatechuate 3,4-dioxygenase
TU94_RS17845	COG0735	belongs to the Fur family
TU94_RS17855	COG1490	D-aminoacyl-tRNA deacylase activity
TU94_RS17885	COG1733	regulation of RNA biosynthetic process
TU94_RS17935	COG0438	transferase activity, transferring glycosyl groups
TU94_RS17960	COG0588	phosphoglycerate mutase activity
TU94_RS17990	COG1278	Cold shock
TU94_RS18010	COG1278	Cold shock
TU94_RS18015	COG0513	Belongs to the DEAD box helicase family
TU94_RS18050	COG5002	protein histidine kinase activity
TU94_RS18065	COG1329	Transcriptional regulator
TU94_RS18070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TU94_RS18075	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TU94_RS18080	COG0215	cysteine-tRNA ligase activity
TU94_RS18085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TU94_RS18105	COG3842	ATPase activity
TU94_RS18110	COG2378	regulation of single-species biofilm formation
TU94_RS18135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TU94_RS18160	COG2197	response regulator
TU94_RS18195	COG5001	Diguanylate cyclase
TU94_RS18195	COG3300	MHYT domain
TU94_RS18210	COG1228	amidohydrolase
TU94_RS18235	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
TU94_RS18240	COG0463	Glycosyl transferase, family 2
TU94_RS18255	COG1278	Cold shock
TU94_RS18260	COG0459	protein refolding
TU94_RS18275	COG3655	Transcriptional regulator
TU94_RS18295	COG1263	PTS System
TU94_RS18295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TU94_RS18300	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
TU94_RS18305	COG1737	Transcriptional regulator
TU94_RS18360	COG3973	AAA domain
TU94_RS18370	COG1061	Type III restriction enzyme res subunit
TU94_RS18395	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
TU94_RS18400	COG1120	ATPase activity
TU94_RS18405	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TU94_RS18410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TU94_RS18425	COG1278	Cold shock
TU94_RS18430	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TU94_RS18435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TU94_RS18445	COG2814	Major facilitator Superfamily
TU94_RS18465	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TU94_RS18480	COG2252	PERMEase
TU94_RS18510	COG0667	Aldo Keto reductase
TU94_RS18545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TU94_RS18550	COG0123	including yeast histone deacetylase and acetoin utilization protein
TU94_RS18595	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TU94_RS18600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TU94_RS18605	COG0181	hydroxymethylbilane synthase activity
TU94_RS18610	COG1648	precorrin-2 dehydrogenase activity
TU94_RS18610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TU94_RS18625	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TU94_RS18650	COG0758	DNA mediated transformation
TU94_RS18660	COG0113	porphobilinogen synthase activity
TU94_RS18675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TU94_RS18685	COG0018	arginyl-trna synthetase
TU94_RS18690	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TU94_RS18710	COG1690	Belongs to the RtcB family
TU94_RS18720	COG1742	UPF0060 membrane protein
TU94_RS18725	COG1846	Transcriptional regulator
TU94_RS18730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS18745	COG2205	protein histidine kinase activity
TU94_RS18760	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TU94_RS18765	COG0406	alpha-ribazole phosphatase activity
TU94_RS18780	COG0785	Cytochrome C biogenesis protein
TU94_RS18785	COG1333	cytochrome c biogenesis protein
TU94_RS18790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TU94_RS18800	COG0789	Transcriptional regulator
TU94_RS18815	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TU94_RS18825	COG0163	prenyltransferase activity
TU94_RS18835	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TU94_RS18840	COG1573	uracil-dna glycosylase
TU94_RS18855	COG1301	dicarboxylic acid transport
TU94_RS18860	COG1309	transcriptional regulator
TU94_RS18880	COG0183	Belongs to the thiolase family
TU94_RS18915	COG2814	Major facilitator Superfamily
TU94_RS18920	COG2226	methyltransferase
TU94_RS18940	COG1278	Cold shock
TU94_RS18945	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TU94_RS18965	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TU94_RS18975	COG3979	chitinase
TU94_RS18995	COG2226	methyltransferase
TU94_RS19010	COG3103	Sh3 type 3 domain protein
TU94_RS19010	COG0791	NLP P60 protein
TU94_RS19010	COG1388	LysM domain
TU94_RS19020	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TU94_RS19025	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TU94_RS19030	COG0649	NAD binding
TU94_RS19040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TU94_RS19045	COG1034	ATP synthesis coupled electron transport
TU94_RS19050	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TU94_RS19055	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TU94_RS19060	COG0839	Belongs to the complex I subunit 6 family
TU94_RS19065	COG0713	ATP synthesis coupled electron transport
TU94_RS19070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TU94_RS19080	COG1007	ATP synthesis coupled electron transport
TU94_RS19090	COG0514	ATP-dependent DNA helicase (RecQ)
TU94_RS19105	COG0561	phosphatase activity
TU94_RS19115	COG0142	geranyltranstransferase activity
TU94_RS19135	COG0655	NAD(P)H dehydrogenase (quinone) activity
TU94_RS19160	COG0702	epimerase
TU94_RS19165	COG1733	regulation of RNA biosynthetic process
TU94_RS19170	COG1013	pyruvate-flavodoxin oxidoreductase activity
TU94_RS19175	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TU94_RS19175	COG0674	pyruvate-flavodoxin oxidoreductase activity
TU94_RS19190	COG4585	Histidine kinase
TU94_RS19195	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TU94_RS19200	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TU94_RS19205	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TU94_RS19210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TU94_RS19215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TU94_RS19220	COG0839	Belongs to the complex I subunit 6 family
TU94_RS19225	COG0713	ATP synthesis coupled electron transport
TU94_RS19230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TU94_RS19245	COG1007	ATP synthesis coupled electron transport
TU94_RS19250	COG0501	Belongs to the peptidase M48B family
TU94_RS19255	COG3304	Inner membrane component domain
TU94_RS19265	COG1666	GTP binding
TU94_RS19280	COG0702	epimerase
TU94_RS19300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TU94_RS19305	COG2030	dehydratase
TU94_RS19320	COG0477	Major facilitator Superfamily
TU94_RS19330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TU94_RS19335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TU94_RS19340	COG0436	Aminotransferase
TU94_RS19355	COG0250	Participates in transcription elongation, termination and antitermination
TU94_RS19360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TU94_RS19365	COG0081	regulation of translation
TU94_RS19385	COG0085	RNA polymerase activity
TU94_RS19390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TU94_RS19400	COG0463	Glycosyl transferase, family 2
TU94_RS19410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TU94_RS19415	COG0049	tRNA binding
TU94_RS19420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TU94_RS19445	COG1132	(ABC) transporter
TU94_RS19460	COG0583	DNA-binding transcription factor activity
TU94_RS19470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TU94_RS19475	COG0051	transcription antitermination factor activity, RNA binding
TU94_RS19480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TU94_RS19485	COG0088	Forms part of the polypeptide exit tunnel
TU94_RS19490	COG0089	rRNA binding
TU94_RS19495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TU94_RS19500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TU94_RS19505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TU94_RS19510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TU94_RS19515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TU94_RS19520	COG0255	Belongs to the universal ribosomal protein uL29 family
TU94_RS19525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TU94_RS19530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TU94_RS19535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TU94_RS19540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TU94_RS19545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TU94_RS19550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TU94_RS19555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TU94_RS19560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TU94_RS19565	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TU94_RS19570	COG1841	ribosomal large subunit assembly
TU94_RS19575	COG0200	Binds to the 23S rRNA
TU94_RS19585	COG0563	adenylate kinase activity
TU94_RS19595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TU94_RS19600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TU94_RS19605	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TU94_RS19610	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TU94_RS19615	COG0202	RNA polymerase activity
TU94_RS19620	COG0203	ribosomal protein L17
TU94_RS19625	COG0101	tRNA pseudouridine synthase activity
TU94_RS19640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TU94_RS19645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TU94_RS19650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TU94_RS19660	COG1072	(Pantothenic acid kinase))
TU94_RS19665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TU94_RS19670	COG0736	holo-[acyl-carrier-protein] synthase activity
TU94_RS19680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TU94_RS19690	COG0802	atpase or kinase
TU94_RS19700	COG0456	acetyltransferase
TU94_RS19700	COG1214	PFAM Peptidase M22, glycoprotease
TU94_RS19710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TU94_RS19720	COG1609	Transcriptional regulator
TU94_RS19735	COG0726	polysaccharide deacetylase
TU94_RS19740	COG0726	polysaccharide deacetylase
TU94_RS19745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TU94_RS19750	COG0459	protein refolding
TU94_RS19765	COG0583	DNA-binding transcription factor activity
TU94_RS19775	COG2197	response regulator
TU94_RS19780	COG1595	DNA-templated transcription, initiation
TU94_RS19790	COG0516	GMP reductase activity
TU94_RS19800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TU94_RS19810	COG2815	serine threonine protein kinase
TU94_RS19810	COG0515	serine threonine protein kinase
TU94_RS19815	COG0515	serine threonine protein kinase
TU94_RS19825	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS19845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TU94_RS19845	COG0519	Catalyzes the synthesis of GMP from XMP
TU94_RS19875	COG2197	response regulator
TU94_RS19880	COG0791	NLP P60 protein
TU94_RS19910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS19910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS19925	COG0714	Associated with various cellular activities
TU94_RS19930	COG2425	protein containing a von Willebrand factor type A (vWA) domain
TU94_RS19935	COG3552	Protein containing von Willebrand factor type A (VWA) domain
TU94_RS19950	COG0045	succinate-CoA ligase (ADP-forming) activity
TU94_RS19980	COG0138	bifunctional purine biosynthesis protein purh
TU94_RS19985	COG2815	serine threonine protein kinase
TU94_RS19985	COG0515	serine threonine protein kinase
TU94_RS19995	COG1714	RDD family
TU94_RS20000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TU94_RS20015	COG0039	L-malate dehydrogenase activity
TU94_RS20035	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS20045	COG0517	IMP dehydrogenase activity
TU94_RS20045	COG4175	Glycine betaine
TU94_RS20065	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TU94_RS20070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TU94_RS20075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TU94_RS20125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TU94_RS20140	COG0754	glutathionylspermidine amidase activity
TU94_RS20150	COG0667	Aldo Keto reductase
TU94_RS20160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TU94_RS20165	COG0180	Tryptophanyl-tRNA synthetase
TU94_RS20185	COG0671	phosphoesterase, PA-phosphatase related
TU94_RS20200	COG1295	ribonuclease BN
TU94_RS20205	COG1686	Belongs to the peptidase S11 family
TU94_RS20215	COG1408	metallophosphoesterase
TU94_RS20250	COG1053	succinate dehydrogenase
TU94_RS20260	COG2009	succinate dehydrogenase
TU94_RS20270	COG3525	Glycosyl hydrolase, family 20, catalytic domain
TU94_RS20300	COG1595	DNA-templated transcription, initiation
TU94_RS20315	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS20315	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS20340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
TU94_RS20360	COG1216	Glycosyl transferase, family 2
TU94_RS20375	COG2089	acid synthase
TU94_RS20385	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
TU94_RS20385	COG1473	amidohydrolase
TU94_RS20390	COG1744	ABC transporter substrate-binding protein PnrA-like
TU94_RS20395	COG1744	ABC transporter substrate-binding protein PnrA-like
TU94_RS20400	COG3845	ABC transporter
TU94_RS20410	COG1079	Belongs to the binding-protein-dependent transport system permease family
TU94_RS20435	COG2814	Major facilitator Superfamily
TU94_RS20440	COG0583	DNA-binding transcription factor activity
TU94_RS20450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TU94_RS20480	COG2205	protein histidine kinase activity
TU94_RS20485	COG0745	RESPONSE REGULATOR receiver
TU94_RS20490	COG1595	DNA-templated transcription, initiation
TU94_RS20505	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS20510	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS20530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TU94_RS20555	COG4770	biotin carboxylase activity
TU94_RS20565	COG0424	maF-like protein
TU94_RS20585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TU94_RS20595	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TU94_RS20610	COG1024	Enoyl-CoA hydratase
TU94_RS20635	COG1404	Belongs to the peptidase S8 family
TU94_RS20645	COG1064	alcohol dehydrogenase
TU94_RS20655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TU94_RS20660	COG0640	Transcriptional regulator
TU94_RS20670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TU94_RS20695	COG2255	four-way junction helicase activity
TU94_RS20700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TU94_RS20705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TU94_RS20715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TU94_RS20725	COG1331	Highly conserved protein containing a thioredoxin domain
TU94_RS20735	COG1309	transcriptional regulator
TU94_RS20745	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TU94_RS20755	COG0640	Transcriptional regulator
TU94_RS20765	COG0436	Aminotransferase
TU94_RS20775	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
TU94_RS20790	COG1414	Transcriptional regulator
TU94_RS20795	COG0251	oxidation-reduction process
TU94_RS20800	COG2610	gluconate transmembrane transporter activity
TU94_RS20850	COG2894	cell division
TU94_RS20880	COG3920	Histidine kinase
TU94_RS20885	COG2197	response regulator
TU94_RS20920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TU94_RS20925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TU94_RS20940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TU94_RS20945	COG0450	alkyl hydroperoxide reductase
TU94_RS20960	COG1136	(ABC) transporter
TU94_RS20980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TU94_RS20995	COG0114	fumarate hydratase activity
TU94_RS21000	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TU94_RS21000	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TU94_RS21025	COG0778	Nitroreductase
TU94_RS21035	COG1722	exodeoxyribonuclease VII activity
TU94_RS21040	COG1570	exodeoxyribonuclease VII activity
TU94_RS21050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TU94_RS21065	COG0012	GTP binding
TU94_RS21075	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TU94_RS21100	COG0583	DNA-binding transcription factor activity
TU94_RS21105	COG0300	oxidoreductase activity
TU94_RS21155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TU94_RS21180	COG1217	gtp-binding protein TYPA
TU94_RS21185	COG4608	Belongs to the ABC transporter superfamily
TU94_RS21190	COG0444	Belongs to the ABC transporter superfamily
TU94_RS21200	COG0747	negative chemotaxis
TU94_RS21205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TU94_RS21215	COG0601	transmembrane transport
TU94_RS21220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TU94_RS21230	COG4608	Belongs to the ABC transporter superfamily
TU94_RS21245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TU94_RS21290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TU94_RS21300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TU94_RS21310	COG0519	Catalyzes the synthesis of GMP from XMP
TU94_RS21320	COG1024	Enoyl-CoA hydratase
TU94_RS21330	COG1595	DNA-templated transcription, initiation
TU94_RS21340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TU94_RS21345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TU94_RS21365	COG2239	Acts as a magnesium transporter
TU94_RS21380	COG0598	Magnesium transport protein CorA
TU94_RS21390	COG2814	Major facilitator Superfamily
TU94_RS21405	COG2095	MarC family integral membrane protein
TU94_RS21410	COG1432	Conserved Protein
TU94_RS21420	COG0513	Belongs to the DEAD box helicase family
TU94_RS21515	COG0210	DNA helicase
TU94_RS21525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TU94_RS21530	COG2816	NAD+ diphosphatase activity
TU94_RS21555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
TU94_RS21605	COG3480	Lon protease (S16) C-terminal proteolytic domain
TU94_RS21615	COG1615	UPF0182 protein
TU94_RS21640	COG0753	catalase activity
TU94_RS21650	COG0483	inositol monophosphate 1-phosphatase activity
TU94_RS21665	COG2076	Multidrug Resistance protein
TU94_RS21675	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TU94_RS21685	COG2135	peptidase activity
TU94_RS21695	COG1595	DNA-templated transcription, initiation
TU94_RS21700	COG5662	AntiSigma factor
TU94_RS21705	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TU94_RS21705	COG2199	diguanylate cyclase activity
TU94_RS21720	COG0242	peptide deformylase activity
TU94_RS21730	COG2124	cytochrome p450
TU94_RS21770	COG2188	Transcriptional regulator
TU94_RS21775	COG2182	Extracellular solute-binding protein
TU94_RS21780	COG1175	transmembrane transport
TU94_RS21785	COG0395	ABC-type sugar transport system, permease component
TU94_RS21790	COG1472	Belongs to the glycosyl hydrolase 3 family
TU94_RS21795	COG0363	glucosamine-6-phosphate deaminase activity
TU94_RS21805	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS21830	COG1597	lipid kinase activity
TU94_RS21860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
TU94_RS21870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TU94_RS21875	COG0142	geranyltranstransferase activity
TU94_RS21910	COG4106	trans-aconitate 2-methyltransferase activity
TU94_RS21930	COG0281	malic enzyme
TU94_RS21935	COG0604	alcohol dehydrogenase
TU94_RS22010	COG0508	dehydrogenase complex catalyzes the overall conversion of
TU94_RS22010	COG0567	Dehydrogenase, E1 component
TU94_RS22015	COG2205	protein histidine kinase activity
TU94_RS22020	COG0745	RESPONSE REGULATOR receiver
TU94_RS22030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TU94_RS22050	COG5002	protein histidine kinase activity
TU94_RS22100	COG0768	penicillin binding
TU94_RS22115	COG2205	protein histidine kinase activity
TU94_RS22135	COG1793	dna ligase
TU94_RS22135	COG3285	dna ligase
TU94_RS22140	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
TU94_RS22190	COG2186	Transcriptional regulator
TU94_RS22295	COG0018	arginyl-trna synthetase
TU94_RS22300	COG0019	diaminopimelate decarboxylase activity
TU94_RS22305	COG0460	homoserine dehydrogenase
TU94_RS22310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TU94_RS22315	COG0083	homoserine kinase activity
TU94_RS22335	COG0254	rRNA binding
TU94_RS22340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TU94_RS22345	COG2890	protein-(glutamine-N5) methyltransferase activity
TU94_RS22355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TU94_RS22360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TU94_RS22365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TU94_RS22370	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS22370	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS22380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TU94_RS22415	COG3321	synthase
TU94_RS22415	COG0604	alcohol dehydrogenase
TU94_RS22425	COG0604	alcohol dehydrogenase
TU94_RS22425	COG3321	synthase
TU94_RS22450	COG3321	synthase
TU94_RS22450	COG3321	synthase
TU94_RS22450	COG0604	alcohol dehydrogenase
TU94_RS22450	COG0604	alcohol dehydrogenase
TU94_RS22455	COG0604	alcohol dehydrogenase
TU94_RS22455	COG3321	synthase
TU94_RS22470	COG0604	alcohol dehydrogenase
TU94_RS22470	COG3321	synthase
TU94_RS22485	COG0604	alcohol dehydrogenase
TU94_RS22505	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TU94_RS22510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TU94_RS22515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TU94_RS22520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TU94_RS22525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TU94_RS22530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TU94_RS22535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TU94_RS22550	COG2197	response regulator
TU94_RS22555	COG4585	Histidine kinase
TU94_RS22590	COG1250	3-hydroxyacyl-CoA dehydrogenase
TU94_RS22605	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
TU94_RS22640	COG1131	(ABC) transporter
TU94_RS22660	COG0183	Belongs to the thiolase family
TU94_RS22675	COG0745	RESPONSE REGULATOR receiver
TU94_RS22725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS22725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS22760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TU94_RS22765	COG0280	phosphate acetyltransferase
TU94_RS22765	COG0857	belongs to the CobB CobQ family
TU94_RS22770	COG0205	6-phosphofructokinase activity
TU94_RS22780	COG0395	ABC-type sugar transport system, permease component
TU94_RS22785	COG1175	transmembrane transport
TU94_RS22805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TU94_RS22815	COG3903	Transcriptional regulator
TU94_RS22815	COG3629	intracellular signal transduction
TU94_RS22820	COG4565	transcriptional regulatory protein
TU94_RS22825	COG3290	protein histidine kinase activity
TU94_RS22830	COG1301	dicarboxylic acid transport
TU94_RS22835	COG0789	Transcriptional regulator
TU94_RS22850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TU94_RS22855	COG3281	Trehalose synthase
TU94_RS22865	COG0366	Alpha amylase catalytic
TU94_RS22870	COG0058	SHG alpha-glucan phosphorylase activity
TU94_RS22885	COG3119	arylsulfatase activity
TU94_RS22920	COG0789	Transcriptional regulator
TU94_RS22930	COG1119	ATPase activity
TU94_RS22970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS22980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS22990	COG2814	Major facilitator Superfamily
TU94_RS23010	COG1760	l-serine dehydratase
TU94_RS23015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TU94_RS23020	COG0509	glycine decarboxylation via glycine cleavage system
TU94_RS23025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TU94_RS23045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TU94_RS23050	COG4166	transmembrane transport
TU94_RS23060	COG0444	Belongs to the ABC transporter superfamily
TU94_RS23065	COG4608	Belongs to the ABC transporter superfamily
TU94_RS23070	COG2860	membrane
TU94_RS23080	COG1309	transcriptional regulator
TU94_RS23105	COG0482	sulfurtransferase activity
TU94_RS23125	COG1611	Belongs to the LOG family
TU94_RS23130	COG4221	oxidoreductase activity
TU94_RS23140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TU94_RS23150	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TU94_RS23155	COG0154	amidase activity
TU94_RS23165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TU94_RS23170	COG2409	Drug exporters of the RND superfamily
TU94_RS23185	COG2133	pyrroloquinoline quinone binding
TU94_RS23190	COG0667	Aldo Keto reductase
TU94_RS23200	COG5001	Diguanylate cyclase
TU94_RS23210	COG0440	acetolactate synthase activity
TU94_RS23215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TU94_RS23220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TU94_RS23225	COG0477	Major facilitator Superfamily
TU94_RS23245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TU94_RS23250	COG0747	negative chemotaxis
TU94_RS23260	COG0506	proline dehydrogenase activity
TU94_RS23265	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS23280	COG0473	3-isopropylmalate dehydrogenase activity
TU94_RS23285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TU94_RS23290	COG0831	urea catabolic process
TU94_RS23290	COG0832	Belongs to the urease beta subunit family
TU94_RS23295	COG0804	urea catabolic process
TU94_RS23300	COG2957	Belongs to the agmatine deiminase family
TU94_RS23310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TU94_RS23330	COG5492	domain, Protein
TU94_RS23335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TU94_RS23355	COG2018	Roadblock/LC7 domain
TU94_RS23375	COG2018	Roadblock/LC7 domain
TU94_RS23380	COG5002	protein histidine kinase activity
TU94_RS23385	COG0179	Fumarylacetoacetate (FAA) hydrolase
TU94_RS23390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TU94_RS23430	COG1414	Transcriptional regulator
TU94_RS23435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TU94_RS23440	COG0066	3-isopropylmalate dehydratase activity
TU94_RS23450	COG0776	regulation of translation
TU94_RS23460	COG1920	GTP binding
TU94_RS23470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TU94_RS23475	COG1181	Belongs to the D-alanine--D-alanine ligase family
TU94_RS23495	COG0351	phosphomethylpyrimidine kinase
TU94_RS23510	COG1461	Dihydroxyacetone kinase
TU94_RS23520	COG0742	ribosomal rna small subunit methyltransferase
TU94_RS23525	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TU94_RS23535	COG1399	metal-binding, possibly nucleic acid-binding protein
TU94_RS23540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TU94_RS23545	COG0571	ribonuclease III activity
TU94_RS23550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TU94_RS23555	COG1733	regulation of RNA biosynthetic process
TU94_RS23560	COG2340	Cysteine-rich secretory protein family
TU94_RS23565	COG1254	Belongs to the acylphosphatase family
TU94_RS23575	COG1196	nuclear chromosome segregation
TU94_RS23580	COG0477	Major facilitator Superfamily
TU94_RS23620	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
TU94_RS23630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TU94_RS23645	COG0228	four-way junction DNA binding
TU94_RS23650	COG1837	Belongs to the UPF0109 family
TU94_RS23655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TU94_RS23660	COG0336	Belongs to the RNA methyltransferase TrmD family
TU94_RS23665	COG0335	large ribosomal subunit rRNA binding
TU94_RS23680	COG0681	Belongs to the peptidase S26 family
TU94_RS23700	COG0792	nuclease activity
TU94_RS23715	COG1191	sigma factor activity
TU94_RS23730	COG0052	Belongs to the universal ribosomal protein uS2 family
TU94_RS23735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TU94_RS23740	COG0528	UMP kinase activity
TU94_RS23745	COG0233	cytoplasmic translational termination
TU94_RS23750	COG0575	Belongs to the CDS family
TU94_RS23755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TU94_RS23765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
TU94_RS23770	COG3842	ATPase activity
TU94_RS23805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TU94_RS23815	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS23845	COG5635	Nacht domain
TU94_RS23845	COG2319	Wd-40 repeat
TU94_RS23850	COG0584	glycerophosphoryl diester phosphodiesterase
TU94_RS23855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TU94_RS23880	COG3842	ATPase activity
TU94_RS23885	COG1176	ABC-type spermidine putrescine transport system, permease component I
TU94_RS23890	COG1177	transmembrane transport
TU94_RS23895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TU94_RS23920	COG2508	Transcriptional regulator
TU94_RS23925	COG1012	belongs to the aldehyde dehydrogenase family
TU94_RS23930	COG1472	Belongs to the glycosyl hydrolase 3 family
TU94_RS23940	COG4209	transmembrane transport
TU94_RS23945	COG0395	ABC-type sugar transport system, permease component
TU94_RS23985	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TU94_RS23990	COG0750	zinc metalloprotease
TU94_RS23995	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TU94_RS24010	COG0442	prolyl-tRNA aminoacylation
TU94_RS24030	COG0779	Required for maturation of 30S ribosomal subunits
TU94_RS24045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TU94_RS24055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TU94_RS24060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TU94_RS24090	COG0601	transmembrane transport
TU94_RS24095	COG0747	negative chemotaxis
TU94_RS24100	COG0455	bacterial-type flagellum organization
TU94_RS24135	COG1404	Belongs to the peptidase S8 family
TU94_RS24145	COG1404	Belongs to the peptidase S8 family
TU94_RS24150	COG1404	Belongs to the peptidase S8 family
TU94_RS24225	COG1674	ftsk spoiiie
TU94_RS24235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TU94_RS24240	COG1185	polyribonucleotide nucleotidyltransferase activity
TU94_RS24245	COG0612	Peptidase, M16
TU94_RS24250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TU94_RS24270	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TU94_RS24275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TU94_RS24280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TU94_RS24310	COG2770	Histidine kinase
TU94_RS24310	COG2208	phosphoserine phosphatase activity
TU94_RS24315	COG0784	Response regulator, receiver
TU94_RS24315	COG2205	protein histidine kinase activity
TU94_RS24325	COG1674	ftsk spoiiie
TU94_RS24335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TU94_RS24345	COG1058	Belongs to the CinA family
TU94_RS24345	COG1546	Belongs to the CinA family
TU94_RS24350	COG1396	sequence-specific DNA binding
TU94_RS24365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TU94_RS24370	COG1201	RNA secondary structure unwinding
TU94_RS24395	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TU94_RS24405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TU94_RS24415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TU94_RS24420	COG0765	amino acid transport
TU94_RS24425	COG0765	amino acid transport
TU94_RS24430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TU94_RS24435	COG1126	abc transporter atp-binding protein
TU94_RS24440	COG0745	RESPONSE REGULATOR receiver
TU94_RS24445	COG2205	protein histidine kinase activity
TU94_RS24450	COG2358	TRAP transporter, solute receptor (TAXI family
TU94_RS24470	COG3851	Histidine kinase
TU94_RS24475	COG2197	response regulator
TU94_RS24490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TU94_RS24510	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TU94_RS24520	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TU94_RS24525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TU94_RS24535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TU94_RS24570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TU94_RS24575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TU94_RS24580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TU94_RS24595	COG0588	phosphoglycerate mutase activity
TU94_RS24610	COG1309	transcriptional regulator
TU94_RS24615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TU94_RS24670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
TU94_RS24680	COG1802	Transcriptional regulator
TU94_RS24685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TU94_RS24700	COG0187	DNA topoisomerase II activity
TU94_RS24710	COG3290	protein histidine kinase activity
TU94_RS24725	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TU94_RS24730	COG0612	Peptidase, M16
TU94_RS24745	COG1802	Transcriptional regulator
TU94_RS24750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TU94_RS24770	COG1435	thymidine kinase activity
TU94_RS24805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TU94_RS24810	COG0483	inositol monophosphate 1-phosphatase activity
TU94_RS24815	COG0745	RESPONSE REGULATOR receiver
TU94_RS24820	COG2205	protein histidine kinase activity
TU94_RS24845	COG0756	dUTP diphosphatase activity
TU94_RS24870	COG0569	domain protein
TU94_RS24875	COG0531	amino acid
TU94_RS24880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TU94_RS24885	COG0464	growth
TU94_RS25000	COG1191	sigma factor activity
TU94_RS25015	COG2770	Histidine kinase
TU94_RS25015	COG2208	phosphoserine phosphatase activity
TU94_RS25040	COG4948	Mandelate Racemase Muconate Lactonizing
TU94_RS25045	COG2186	Transcriptional regulator
TU94_RS25050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TU94_RS25070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
TU94_RS25095	COG4977	sequence-specific DNA binding
TU94_RS25145	COG0179	Fumarylacetoacetate (FAA) hydrolase
TU94_RS25160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TU94_RS25170	COG0179	Fumarylacetoacetate (FAA) hydrolase
TU94_RS25180	COG1122	ATPase activity
TU94_RS25190	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
TU94_RS25195	COG0310	cobalt ion transport
TU94_RS25200	COG1799	cell septum assembly
TU94_RS25235	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TU94_RS25240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
TU94_RS25245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TU94_RS25250	COG0531	amino acid
TU94_RS25260	COG1024	Enoyl-CoA hydratase
TU94_RS25305	COG0583	DNA-binding transcription factor activity
TU94_RS25345	COG0210	DNA helicase
TU94_RS25355	COG1401	restriction endodeoxyribonuclease activity
TU94_RS25435	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TU94_RS25440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TU94_RS25455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TU94_RS25465	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TU94_RS25470	COG0583	DNA-binding transcription factor activity
TU94_RS25495	COG1653	transport
TU94_RS25500	COG1175	transmembrane transport
TU94_RS25505	COG0395	ABC-type sugar transport system, permease component
TU94_RS25510	COG1940	carbohydrate kinase activity
TU94_RS25515	COG4213	ABC transporter substrate-binding protein
TU94_RS25525	COG4214	carbohydrate transport
TU94_RS25530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TU94_RS25535	COG0531	amino acid
TU94_RS25565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TU94_RS25585	COG1024	Enoyl-CoA hydratase
TU94_RS25585	COG1250	3-hydroxyacyl-CoA dehydrogenase
TU94_RS25590	COG0183	Belongs to the thiolase family
TU94_RS25595	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
TU94_RS25610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TU94_RS25655	COG0464	growth
TU94_RS25745	COG0477	Major facilitator Superfamily
TU94_RS25750	COG1115	amino acid carrier protein
TU94_RS25760	COG0446	pyridine nucleotide-disulphide oxidoreductase
TU94_RS25770	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TU94_RS25775	COG3253	May function as heme-dependent peroxidase
TU94_RS25790	COG3220	belongs to the UPF0276 family
TU94_RS25860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TU94_RS25860	COG0723	plastoquinol--plastocyanin reductase activity
TU94_RS25870	COG0330	HflC and HflK could
TU94_RS25905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TU94_RS25910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TU94_RS25920	COG1174	glycine betaine transport
TU94_RS25925	COG1174	glycine betaine transport
TU94_RS25930	COG1732	Glycine betaine
TU94_RS25960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TU94_RS25970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TU94_RS25990	COG1716	ATPase activity
TU94_RS26005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TU94_RS26010	COG0583	DNA-binding transcription factor activity
TU94_RS26055	COG1175	transmembrane transport
TU94_RS26085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TU94_RS26090	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
TU94_RS26115	COG0529	Catalyzes the synthesis of activated sulfate
TU94_RS26120	COG0175	sulfate reduction
TU94_RS26125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TU94_RS26145	COG1960	acyl-CoA dehydrogenase activity
TU94_RS26155	COG0789	Transcriptional regulator
TU94_RS26160	COG1819	glycosyl
TU94_RS26195	COG2353	YceI-like domain
TU94_RS26200	COG1609	Transcriptional regulator
TU94_RS26235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TU94_RS26250	COG2040	homocysteine
TU94_RS26260	COG2755	lipolytic protein G-D-S-L family
TU94_RS26280	COG2814	Major facilitator Superfamily
TU94_RS26295	COG0438	transferase activity, transferring glycosyl groups
TU94_RS26305	COG0596	Alpha beta hydrolase
TU94_RS26325	COG0277	FAD linked oxidase domain protein
TU94_RS26345	COG1162	GTPase activity
TU94_RS26355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TU94_RS26375	COG0028	Belongs to the TPP enzyme family
TU94_RS26395	COG1802	Transcriptional regulator
TU94_RS26400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TU94_RS26410	COG2197	response regulator
TU94_RS26415	COG3851	Histidine kinase
TU94_RS26450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
TU94_RS26455	COG2252	PERMEase
TU94_RS26470	COG2132	Multicopper oxidase
TU94_RS26475	COG0726	polysaccharide deacetylase
TU94_RS26480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TU94_RS26485	COG2192	nodulation
TU94_RS26495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
TU94_RS26500	COG0859	PFAM glycosyl transferase family 9
TU94_RS26505	COG0438	transferase activity, transferring glycosyl groups
TU94_RS26515	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
TU94_RS26520	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TU94_RS26520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TU94_RS26560	COG2197	response regulator
TU94_RS26565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TU94_RS26570	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS26575	COG0477	Major facilitator Superfamily
TU94_RS26585	COG3960	tartronate-semialdehyde synthase activity
TU94_RS26590	COG0384	phenazine biosynthesis protein PhzF
TU94_RS26620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TU94_RS26660	COG0753	catalase activity
TU94_RS26665	COG2084	Dehydrogenase
TU94_RS26670	COG3622	Belongs to the hyi family
TU94_RS26690	COG2351	hydroxyisourate hydrolase activity
TU94_RS26700	COG2233	PERMEase
TU94_RS26710	COG2233	PERMEase
TU94_RS26735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TU94_RS26745	COG0406	alpha-ribazole phosphatase activity
TU94_RS26755	COG1733	regulation of RNA biosynthetic process
TU94_RS26770	COG4264	IucA IucC family
TU94_RS26795	COG1191	sigma factor activity
TU94_RS26805	COG0154	amidase activity
TU94_RS26820	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TU94_RS26835	COG1414	Transcriptional regulator
TU94_RS26840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TU94_RS26845	COG4266	Belongs to the allantoicase family
TU94_RS26850	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS26870	COG0673	inositol 2-dehydrogenase activity
TU94_RS26875	COG2188	Transcriptional regulator
TU94_RS26895	COG1940	carbohydrate kinase activity
TU94_RS26905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TU94_RS26930	COG0702	epimerase
TU94_RS26960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TU94_RS26975	COG0395	ABC-type sugar transport system, permease component
TU94_RS26980	COG1175	transmembrane transport
TU94_RS26990	COG3250	beta-galactosidase activity
TU94_RS26995	COG1609	Transcriptional regulator
TU94_RS27005	COG1482	cell wall glycoprotein biosynthetic process
TU94_RS27045	COG0326	Molecular chaperone. Has ATPase activity
TU94_RS27060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TU94_RS27085	COG0405	Gamma-glutamyltransferase
TU94_RS27120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TU94_RS27125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TU94_RS27135	COG0789	Transcriptional regulator
TU94_RS27140	COG2814	Major facilitator Superfamily
TU94_RS27150	COG0702	epimerase
TU94_RS27190	COG1609	Transcriptional regulator
TU94_RS27195	COG1653	transport
TU94_RS27200	COG1175	transmembrane transport
TU94_RS27210	COG1472	Belongs to the glycosyl hydrolase 3 family
TU94_RS27220	COG1309	transcriptional regulator
TU94_RS27245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TU94_RS27275	COG0483	inositol monophosphate 1-phosphatase activity
TU94_RS27285	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TU94_RS27300	COG0640	Transcriptional regulator
TU94_RS27320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TU94_RS27335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TU94_RS27350	COG0477	Major facilitator Superfamily
TU94_RS27380	COG2124	cytochrome p450
TU94_RS27385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TU94_RS27390	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TU94_RS27395	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TU94_RS27410	COG1929	Belongs to the glycerate kinase type-1 family
TU94_RS27420	COG0688	phosphatidylethanolamine metabolic process
TU94_RS27425	COG1960	acyl-CoA dehydrogenase activity
TU94_RS27435	COG2301	Belongs to the HpcH HpaI aldolase family
TU94_RS27440	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS27440	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TU94_RS27455	COG1250	3-hydroxyacyl-CoA dehydrogenase
TU94_RS27495	COG2362	D-Aminopeptidase
TU94_RS27500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TU94_RS27510	COG1619	proteins homologs of microcin C7 resistance protein MccF
TU94_RS27530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS27545	COG1793	dna ligase
TU94_RS27545	COG3285	dna ligase
TU94_RS27605	COG2226	methyltransferase
TU94_RS27610	COG1597	lipid kinase activity
TU94_RS27615	COG0488	(ABC) transporter
TU94_RS27635	COG0517	IMP dehydrogenase activity
TU94_RS27635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TU94_RS27650	COG0028	Belongs to the TPP enzyme family
TU94_RS27695	COG0531	amino acid
TU94_RS27705	COG0443	Heat shock 70 kDa protein
TU94_RS27720	COG1140	nitrate reductase beta subunit
TU94_RS27745	COG2154	pterin-4-alpha-carbinolamine dehydratase
TU94_RS27750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
TU94_RS27750	COG4106	trans-aconitate 2-methyltransferase activity
TU94_RS27755	COG3401	FG-GAP repeat protein
TU94_RS27765	COG5297	Belongs to the glycosyl hydrolase family 6
TU94_RS27765	COG4733	cellulase activity
TU94_RS27770	COG5297	Belongs to the glycosyl hydrolase family 6
TU94_RS27780	COG0656	L-ascorbic acid biosynthetic process
TU94_RS27820	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
TU94_RS27825	COG1691	(AIR) carboxylase
TU94_RS27830	COG1606	tRNA processing
TU94_RS27835	COG0604	alcohol dehydrogenase
TU94_RS27835	COG3321	synthase
TU94_RS27835	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS27845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TU94_RS27850	COG1309	transcriptional regulator
TU94_RS27915	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TU94_RS27925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TU94_RS27940	COG1940	carbohydrate kinase activity
TU94_RS27945	COG1129	ABC transporter
TU94_RS27950	COG1172	Belongs to the binding-protein-dependent transport system permease family
TU94_RS27960	COG0673	inositol 2-dehydrogenase activity
TU94_RS28025	COG2223	nitrite transmembrane transporter activity
TU94_RS28035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TU94_RS28055	COG2273	Hydrolase Family 16
TU94_RS28070	COG0747	negative chemotaxis
TU94_RS28090	COG0477	Major facilitator Superfamily
TU94_RS28185	COG0305	Participates in initiation and elongation during chromosome replication
TU94_RS28245	COG2186	Transcriptional regulator
TU94_RS28515	COG2188	Transcriptional regulator
TU94_RS28535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TU94_RS28540	COG1082	Xylose isomerase domain protein TIM barrel
TU94_RS28540	COG3185	4-Hydroxyphenylpyruvate dioxygenase
TU94_RS28545	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
TU94_RS28550	COG0166	Belongs to the GPI family
TU94_RS28565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TU94_RS28595	COG1486	melibiose metabolic process
TU94_RS28605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TU94_RS28660	COG0477	Major facilitator Superfamily
TU94_RS28665	COG3511	phospholipase C
TU94_RS28690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
TU94_RS28695	COG0477	Major facilitator Superfamily
TU94_RS28700	COG1672	PFAM Archaeal ATPase
TU94_RS28700	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TU94_RS28705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TU94_RS28710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TU94_RS28715	COG3485	protocatechuate 3,4-dioxygenase
TU94_RS28720	COG3485	protocatechuate 3,4-dioxygenase
TU94_RS28750	COG1063	alcohol dehydrogenase
TU94_RS28755	COG1793	dna ligase
TU94_RS28795	COG1834	amidinotransferase
TU94_RS28820	COG0488	(ABC) transporter
TU94_RS28835	COG1515	deoxyribonuclease V activity
TU94_RS28850	COG3268	Saccharopine dehydrogenase
TU94_RS28855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TU94_RS28860	COG0183	Belongs to the thiolase family
TU94_RS28865	COG1024	Enoyl-CoA hydratase
TU94_RS28865	COG1250	3-hydroxyacyl-CoA dehydrogenase
TU94_RS28875	COG1113	amino acid transport
TU94_RS28885	COG2936	dipeptidyl-peptidase activity
TU94_RS28895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TU94_RS28905	COG0488	(ABC) transporter
TU94_RS28915	COG1486	melibiose metabolic process
TU94_RS28920	COG0395	ABC-type sugar transport system, permease component
TU94_RS28925	COG1175	transmembrane transport
TU94_RS28930	COG1653	transport
TU94_RS28935	COG1846	Transcriptional regulator
TU94_RS28935	COG1940	carbohydrate kinase activity
TU94_RS28950	COG2183	response to ionizing radiation
TU94_RS28960	COG4977	sequence-specific DNA binding
TU94_RS28970	COG1024	Enoyl-CoA hydratase
TU94_RS29000	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
TU94_RS29040	COG1134	teichoic acid transport
TU94_RS29045	COG1562	ergosterol biosynthetic process
TU94_RS29055	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TU94_RS29065	COG1657	PFAM Prenyltransferase squalene oxidase
TU94_RS29080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TU94_RS29100	COG2365	Tyrosine phosphatase family
TU94_RS29115	COG2755	lipolytic protein G-D-S-L family
TU94_RS29150	COG0515	serine threonine protein kinase
TU94_RS29150	COG2815	serine threonine protein kinase
TU94_RS29180	COG2015	COG2015, Alkyl sulfatase and related hydrolases
TU94_RS29245	COG2755	lipolytic protein G-D-S-L family
TU94_RS29325	COG1063	alcohol dehydrogenase
TU94_RS29330	COG0156	8-amino-7-oxononanoate synthase activity
TU94_RS29335	COG0583	DNA-binding transcription factor activity
TU94_RS29355	COG3958	Transketolase
TU94_RS29360	COG3959	Transketolase, thiamine diphosphate binding domain
TU94_RS29370	COG1874	Beta-galactosidase
TU94_RS29370	COG0366	Alpha amylase catalytic
TU94_RS29390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TU94_RS29410	COG1595	DNA-templated transcription, initiation
TU94_RS29425	COG1132	(ABC) transporter
TU94_RS29450	COG0783	Belongs to the Dps family
TU94_RS29460	COG2267	carboxylic ester hydrolase activity
TU94_RS29465	COG0183	Belongs to the thiolase family
TU94_RS29470	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS29575	COG3345	alpha-galactosidase
TU94_RS29605	COG3387	PFAM Glycoside hydrolase 15-related
TU94_RS29620	COG1082	Xylose isomerase domain protein TIM barrel
TU94_RS29655	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS29655	COG3321	synthase
TU94_RS29655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS29655	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS29655	COG0300	oxidoreductase activity
TU94_RS29665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TU94_RS29685	COG0657	acetylesterase activity
TU94_RS29690	COG3962	Belongs to the TPP enzyme family
TU94_RS29695	COG3718	enzyme involved in inositol metabolism
TU94_RS29730	COG0673	inositol 2-dehydrogenase activity
TU94_RS29735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TU94_RS29745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TU94_RS29750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TU94_RS29765	COG2814	Major facilitator Superfamily
TU94_RS29770	COG0385	Bile acid
TU94_RS29780	COG1309	transcriptional regulator
TU94_RS29785	COG0154	amidase activity
TU94_RS29795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS29825	COG0251	oxidation-reduction process
TU94_RS29830	COG0477	Major facilitator Superfamily
TU94_RS29865	COG2838	Isocitrate dehydrogenase
TU94_RS29870	COG0668	transmembrane transport
TU94_RS29880	COG1132	(ABC) transporter
TU94_RS29895	COG3552	Protein containing von Willebrand factor type A (VWA) domain
TU94_RS29900	COG0714	Associated with various cellular activities
TU94_RS29955	COG1505	serine-type exopeptidase activity
TU94_RS29965	COG0477	Major facilitator Superfamily
TU94_RS29975	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS29980	COG1309	transcriptional regulator
TU94_RS29995	COG0456	acetyltransferase
TU94_RS30030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TU94_RS30035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TU94_RS30040	COG1120	ATPase activity
TU94_RS30065	COG1132	(ABC) transporter
TU94_RS30070	COG1132	(ABC) transporter
TU94_RS30075	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
TU94_RS30095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TU94_RS30100	COG1120	ATPase activity
TU94_RS30120	COG2175	clavaminate synthase activity
TU94_RS30130	COG4521	taurine ABC transporter
TU94_RS30135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TU94_RS30150	COG0431	NADPH-dependent FMN reductase
TU94_RS30160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS30185	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TU94_RS30210	COG0297	glycogen (starch) synthase activity
TU94_RS30215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TU94_RS30260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TU94_RS30285	COG0596	Alpha beta hydrolase
TU94_RS30290	COG0531	amino acid
TU94_RS30330	COG5001	Diguanylate cyclase
TU94_RS30335	COG0583	DNA-binding transcription factor activity
TU94_RS30345	COG1053	succinate dehydrogenase
TU94_RS30350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TU94_RS30360	COG1733	regulation of RNA biosynthetic process
TU94_RS30395	COG3693	PFAM glycoside hydrolase, family 10
TU94_RS30410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS30415	COG0523	cobalamin synthesis protein
TU94_RS30430	COG3360	Dodecin
TU94_RS30435	COG2182	Extracellular solute-binding protein
TU94_RS30440	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
TU94_RS30445	COG0121	glutamine amidotransferase
TU94_RS30450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TU94_RS30475	COG1881	PFAM PEBP family protein
TU94_RS30480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TU94_RS30490	COG0251	oxidation-reduction process
TU94_RS30515	COG1053	succinate dehydrogenase
TU94_RS30515	COG3976	FMN-binding domain protein
TU94_RS30540	COG0583	DNA-binding transcription factor activity
TU94_RS30555	COG1609	Transcriptional regulator
TU94_RS30560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TU94_RS30565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TU94_RS30570	COG0242	peptide deformylase activity
TU94_RS30580	COG2124	cytochrome p450
TU94_RS30605	COG3251	PFAM MbtH domain protein
TU94_RS30615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS30665	COG1960	acyl-CoA dehydrogenase activity
TU94_RS30675	COG1250	3-hydroxyacyl-CoA dehydrogenase
TU94_RS30705	COG2274	protein secretion by the type I secretion system
TU94_RS30710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TU94_RS30715	COG0583	DNA-binding transcription factor activity
TU94_RS30720	COG2610	gluconate transmembrane transporter activity
TU94_RS30795	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS30810	COG3467	pyridoxamine 5'-phosphate
TU94_RS30820	COG0765	amino acid transport
TU94_RS30825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TU94_RS30840	COG0765	amino acid transport
TU94_RS30845	COG1126	abc transporter atp-binding protein
TU94_RS30850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TU94_RS30870	COG3903	Transcriptional regulator
TU94_RS30870	COG3629	intracellular signal transduction
TU94_RS30875	COG0596	Alpha beta hydrolase
TU94_RS30900	COG0477	Major facilitator Superfamily
TU94_RS30905	COG1846	Transcriptional regulator
TU94_RS30930	COG0601	transmembrane transport
TU94_RS30935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TU94_RS30940	COG0444	Belongs to the ABC transporter superfamily
TU94_RS30970	COG0514	ATP-dependent DNA helicase (RecQ)
TU94_RS30985	COG1982	Orn Lys Arg decarboxylase major
TU94_RS31020	COG3540	Alkaline phosphatase
TU94_RS31045	COG1556	Lactate utilization protein
TU94_RS31050	COG1139	Iron-sulfur cluster binding protein
TU94_RS31055	COG0247	lactate metabolic process
TU94_RS31060	COG1070	Carbohydrate kinase
TU94_RS31065	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS31065	COG3347	Dehydrogenase
TU94_RS31070	COG4952	isomerase
TU94_RS31075	COG1129	ABC transporter
TU94_RS31080	COG1172	Belongs to the binding-protein-dependent transport system permease family
TU94_RS31090	COG1879	ABC-type sugar transport system periplasmic component
TU94_RS31100	COG1609	Transcriptional regulator
TU94_RS31115	COG1595	DNA-templated transcription, initiation
TU94_RS31120	COG1357	PFAM Pentapeptide repeats (8 copies)
TU94_RS31125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TU94_RS31125	COG2124	cytochrome p450
TU94_RS31130	COG1309	transcriptional regulator
TU94_RS31155	COG4585	Histidine kinase
TU94_RS31160	COG2197	response regulator
TU94_RS31170	COG2814	Major facilitator Superfamily
TU94_RS31200	COG0501	Belongs to the peptidase M48B family
TU94_RS31265	COG1796	DNA polymerase
TU94_RS31265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TU94_RS31270	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS31295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TU94_RS31335	COG2124	cytochrome p450
TU94_RS31340	COG5297	Belongs to the glycosyl hydrolase family 6
TU94_RS31355	COG0435	Glutathione S-transferase
TU94_RS31380	COG0667	Aldo Keto reductase
TU94_RS31395	COG3250	beta-galactosidase activity
TU94_RS31415	COG1304	FMN binding
TU94_RS31435	COG2890	protein-(glutamine-N5) methyltransferase activity
TU94_RS31450	COG0248	Ppx GppA phosphatase
TU94_RS31455	COG2274	protein secretion by the type I secretion system
TU94_RS31485	COG0517	IMP dehydrogenase activity
TU94_RS31525	COG2070	2-Nitropropane dioxygenase
TU94_RS31535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TU94_RS31600	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TU94_RS31615	COG0673	inositol 2-dehydrogenase activity
TU94_RS31630	COG2508	Transcriptional regulator
TU94_RS31680	COG1132	(ABC) transporter
TU94_RS31690	COG4977	sequence-specific DNA binding
TU94_RS31725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
TU94_RS31730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
TU94_RS31735	COG2080	2 iron, 2 sulfur cluster binding
TU94_RS31750	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS31760	COG1295	ribonuclease BN
TU94_RS31775	COG0318	PFAM AMP-dependent synthetase and ligase
TU94_RS31780	COG1024	Enoyl-CoA hydratase
TU94_RS31805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TU94_RS31825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TU94_RS31855	COG0477	Major facilitator Superfamily
TU94_RS31905	COG0277	FAD linked oxidase domain protein
TU94_RS31925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TU94_RS31930	COG0395	ABC-type sugar transport system, permease component
TU94_RS31935	COG1175	transmembrane transport
TU94_RS31950	COG2264	protein methyltransferase activity
TU94_RS32025	COG1116	anion transmembrane transporter activity
TU94_RS32045	COG0739	heme binding
TU94_RS32050	COG0488	(ABC) transporter
TU94_RS32080	COG0563	adenylate kinase activity
TU94_RS32090	COG1309	transcriptional regulator
TU94_RS32100	COG4221	oxidoreductase activity
TU94_RS32120	COG1733	regulation of RNA biosynthetic process
TU94_RS32165	COG0395	ABC-type sugar transport system, permease component
TU94_RS32170	COG1175	transmembrane transport
TU94_RS32175	COG2182	Extracellular solute-binding protein
TU94_RS32180	COG3485	protocatechuate 3,4-dioxygenase
TU94_RS32185	COG1454	alcohol dehydrogenase
TU94_RS32200	COG0442	prolyl-tRNA aminoacylation
TU94_RS32205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TU94_RS32210	COG1132	(ABC) transporter
TU94_RS32215	COG1024	Enoyl-CoA hydratase
TU94_RS32230	COG1132	(ABC) transporter
TU94_RS32255	COG1051	belongs to the nudix hydrolase family
TU94_RS32295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS32305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TU94_RS32315	COG1231	oxidoreductase activity
TU94_RS32345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TU94_RS32350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TU94_RS32365	COG1063	alcohol dehydrogenase
TU94_RS32385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TU94_RS32405	COG1028	Short-chain dehydrogenase reductase Sdr
TU94_RS32410	COG3708	Transcriptional regulator
TU94_RS32410	COG2207	Transcriptional regulator
TU94_RS32470	COG0366	Alpha amylase catalytic
TU94_RS32475	COG0604	alcohol dehydrogenase
TU94_RS32475	COG3321	synthase
TU94_RS32490	COG3321	synthase
TU94_RS32490	COG0604	alcohol dehydrogenase
TU94_RS32510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TU94_RS32510	COG0515	serine threonine protein kinase
TU94_RS32565	COG1940	carbohydrate kinase activity
TU94_RS32570	COG1082	Xylose isomerase domain protein TIM barrel
TU94_RS32660	COG0515	serine threonine protein kinase
TU94_RS32665	COG0443	Heat shock 70 kDa protein
TU94_RS32695	COG1846	Transcriptional regulator