locus-tag	class	description
IM697_RS00015	COG0640	Transcriptional regulator
IM697_RS00035	COG2255	four-way junction helicase activity
IM697_RS00050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM697_RS00065	COG5002	protein histidine kinase activity
IM697_RS00070	COG0745	RESPONSE REGULATOR receiver
IM697_RS00105	COG0714	Associated with various cellular activities
IM697_RS00135	COG0667	Aldo Keto reductase
IM697_RS00155	COG2264	protein methyltransferase activity
IM697_RS00170	COG0248	Ppx GppA phosphatase
IM697_RS00175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS00195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_RS00235	COG2188	Transcriptional regulator
IM697_RS00280	COG2409	Drug exporters of the RND superfamily
IM697_RS00285	COG4585	Histidine kinase
IM697_RS00305	COG0714	Associated with various cellular activities
IM697_RS00350	COG1132	(ABC) transporter
IM697_RS00365	COG0482	sulfurtransferase activity
IM697_RS00405	COG0366	Alpha amylase catalytic
IM697_RS00420	COG1957	nucleoside hydrolase
IM697_RS00425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IM697_RS00435	COG0701	Predicted permease
IM697_RS00450	COG0222	ribosome binding
IM697_RS00465	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_RS00465	COG2319	Wd-40 repeat
IM697_RS00515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_RS00520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IM697_RS00555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM697_RS00560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IM697_RS00575	COG1289	transmembrane transporter activity
IM697_RS00585	COG0583	DNA-binding transcription factor activity
IM697_RS00600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM697_RS00655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IM697_RS00670	COG1741	Belongs to the pirin family
IM697_RS00675	COG0477	Major facilitator Superfamily
IM697_RS00695	COG1960	acyl-CoA dehydrogenase activity
IM697_RS00700	COG1362	aminopeptidase activity
IM697_RS00750	COG2271	Major facilitator Superfamily
IM697_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM697_RS00770	COG0022	dehydrogenase e1 component
IM697_RS00780	COG0515	serine threonine protein kinase
IM697_RS00785	COG0515	serine threonine protein kinase
IM697_RS00805	COG3321	synthase
IM697_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS00805	COG0604	alcohol dehydrogenase
IM697_RS00820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM697_RS00850	COG1522	sequence-specific DNA binding
IM697_RS00855	COG1309	transcriptional regulator
IM697_RS00860	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_RS00885	COG1960	acyl-CoA dehydrogenase activity
IM697_RS00905	COG1733	regulation of RNA biosynthetic process
IM697_RS00910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IM697_RS00925	COG2319	Wd-40 repeat
IM697_RS00925	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_RS00935	COG0438	transferase activity, transferring glycosyl groups
IM697_RS00955	COG1716	ATPase activity
IM697_RS00960	COG1716	ATPase activity
IM697_RS00975	COG0768	penicillin binding
IM697_RS00980	COG0515	serine threonine protein kinase
IM697_RS00995	COG3764	Sortase (surface protein transpeptidase)
IM697_RS01000	COG3764	Sortase (surface protein transpeptidase)
IM697_RS01015	COG3764	Sortase (surface protein transpeptidase)
IM697_RS01030	COG0705	Rhomboid family
IM697_RS01055	COG0515	serine threonine protein kinase
IM697_RS01075	COG1116	anion transmembrane transporter activity
IM697_RS01090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IM697_RS01095	COG0187	DNA topoisomerase II activity
IM697_RS01100	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
IM697_RS01105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM697_RS01110	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IM697_RS01115	COG0592	DNA-directed DNA polymerase activity
IM697_RS01120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM697_RS01125	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IM697_RS01130	COG0594	ribonuclease P activity
IM697_RS01135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IM697_RS01140	COG0706	membrane insertase activity
IM697_RS01150	COG0357	Ribosomal RNA small subunit methyltransferase G
IM697_RS01155	COG1192	Involved in chromosome partitioning
IM697_RS01170	COG3118	belongs to the thioredoxin family
IM697_RS01175	COG0492	ferredoxin-NADP+ reductase activity
IM697_RS01185	COG1595	DNA-templated transcription, initiation
IM697_RS01190	COG0515	serine threonine protein kinase
IM697_RS01190	COG2815	serine threonine protein kinase
IM697_RS01205	COG0617	tRNA 3'-terminal CCA addition
IM697_RS01230	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IM697_RS01255	COG0360	Binds together with S18 to 16S ribosomal RNA
IM697_RS01260	COG0629	single-stranded DNA binding
IM697_RS01265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IM697_RS01270	COG0359	binds to the 23S rRNA
IM697_RS01280	COG0305	Participates in initiation and elongation during chromosome replication
IM697_RS01290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_RS01305	COG2814	Major facilitator Superfamily
IM697_RS01340	COG0626	cystathionine gamma-synthase activity
IM697_RS01345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM697_RS01350	COG1950	PFAM Membrane protein of
IM697_RS01355	COG0662	Cupin 2, conserved barrel domain protein
IM697_RS01380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IM697_RS01395	COG1609	Transcriptional regulator
IM697_RS01400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM697_RS01410	COG1271	oxidase subunit
IM697_RS01415	COG1294	oxidase, subunit
IM697_RS01420	COG4988	ABC transporter
IM697_RS01430	COG0561	phosphatase activity
IM697_RS01445	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IM697_RS01450	COG0789	Transcriptional regulator
IM697_RS01495	COG0561	phosphatase activity
IM697_RS01500	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM697_RS01510	COG2837	iron assimilation
IM697_RS01525	COG1999	signal sequence binding
IM697_RS01560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_RS01565	COG0006	proline dipeptidase activity
IM697_RS01585	COG0653	protein targeting
IM697_RS01600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_RS01680	COG3328	transposase activity
IM697_RS01725	COG1595	DNA-templated transcription, initiation
IM697_RS01730	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS01735	COG0784	Response regulator, receiver
IM697_RS01760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS01765	COG1335	isochorismatase
IM697_RS01770	COG0431	NADPH-dependent FMN reductase
IM697_RS01780	COG1733	regulation of RNA biosynthetic process
IM697_RS01785	COG1846	Transcriptional regulator
IM697_RS01815	COG0745	RESPONSE REGULATOR receiver
IM697_RS01820	COG2205	protein histidine kinase activity
IM697_RS01830	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IM697_RS01835	COG0477	Major facilitator Superfamily
IM697_RS01845	COG3467	pyridoxamine 5'-phosphate
IM697_RS01850	COG2353	YceI-like domain
IM697_RS01855	COG0477	Major facilitator Superfamily
IM697_RS01875	COG1191	sigma factor activity
IM697_RS01880	COG1191	sigma factor activity
IM697_RS01915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IM697_RS01985	COG1725	Transcriptional regulator
IM697_RS02000	COG3328	transposase activity
IM697_RS02040	COG0395	ABC-type sugar transport system, permease component
IM697_RS02045	COG3345	alpha-galactosidase
IM697_RS02055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM697_RS02060	COG3896	Chloramphenicol phosphotransferase-like protein
IM697_RS02075	COG0438	transferase activity, transferring glycosyl groups
IM697_RS02080	COG0438	transferase activity, transferring glycosyl groups
IM697_RS02100	COG1131	(ABC) transporter
IM697_RS02145	COG2188	Transcriptional regulator
IM697_RS02155	COG2188	Transcriptional regulator
IM697_RS02225	COG0151	Belongs to the GarS family
IM697_RS02240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IM697_RS02250	COG2197	response regulator
IM697_RS02285	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM697_RS02290	COG0047	phosphoribosylformylglycinamidine synthase activity
IM697_RS02295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM697_RS02320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IM697_RS02355	COG1643	Atp-dependent helicase
IM697_RS02390	COG0513	Belongs to the DEAD box helicase family
IM697_RS02405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IM697_RS02415	COG1733	regulation of RNA biosynthetic process
IM697_RS02420	COG0667	Aldo Keto reductase
IM697_RS02425	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS02430	COG1309	transcriptional regulator
IM697_RS02445	COG2226	methyltransferase
IM697_RS02465	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_RS02470	COG2814	Major facilitator Superfamily
IM697_RS02480	COG1309	transcriptional regulator
IM697_RS02525	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_RS02535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM697_RS02535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM697_RS02565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IM697_RS02570	COG0579	oxidoreductase
IM697_RS02590	COG1131	(ABC) transporter
IM697_RS02625	COG1252	NADH dehydrogenase
IM697_RS02660	COG2197	response regulator
IM697_RS02665	COG4585	Histidine kinase
IM697_RS02705	COG1846	Transcriptional regulator
IM697_RS02720	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS02730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_RS02745	COG0739	heme binding
IM697_RS02745	COG0741	lytic transglycosylase activity
IM697_RS02745	COG1196	nuclear chromosome segregation
IM697_RS02750	COG0671	phosphoesterase, PA-phosphatase related
IM697_RS02755	COG2801	Transposase and inactivated derivatives
IM697_RS02755	COG3415	Transposase
IM697_RS02770	COG0277	FAD linked oxidase domain protein
IM697_RS02775	COG0306	phosphate transporter
IM697_RS02785	COG1937	Protein conserved in bacteria
IM697_RS02800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM697_RS02820	COG0406	alpha-ribazole phosphatase activity
IM697_RS02820	COG0494	nUDIX hydrolase
IM697_RS02830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IM697_RS02845	COG3842	ATPase activity
IM697_RS02850	COG1725	Transcriptional regulator
IM697_RS02855	COG0456	acetyltransferase
IM697_RS02860	COG0737	Belongs to the 5'-nucleotidase family
IM697_RS02890	COG0745	RESPONSE REGULATOR receiver
IM697_RS02900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_RS02910	COG1609	Transcriptional regulator
IM697_RS02915	COG0745	RESPONSE REGULATOR receiver
IM697_RS02945	COG2897	thiosulfate sulfurtransferase activity
IM697_RS02980	COG3485	protocatechuate 3,4-dioxygenase
IM697_RS02990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IM697_RS02995	COG1490	D-aminoacyl-tRNA deacylase activity
IM697_RS03005	COG4552	Acetyltransferase involved in intracellular survival and related
IM697_RS03015	COG2188	Transcriptional regulator
IM697_RS03025	COG2188	Transcriptional regulator
IM697_RS03065	COG3973	AAA domain
IM697_RS03080	COG1733	regulation of RNA biosynthetic process
IM697_RS03100	COG3415	Transposase
IM697_RS03100	COG2801	Transposase and inactivated derivatives
IM697_RS03115	COG2267	carboxylic ester hydrolase activity
IM697_RS03175	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IM697_RS03180	COG0438	transferase activity, transferring glycosyl groups
IM697_RS03210	COG0588	phosphoglycerate mutase activity
IM697_RS03230	COG5002	protein histidine kinase activity
IM697_RS03245	COG1329	Transcriptional regulator
IM697_RS03250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IM697_RS03255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IM697_RS03260	COG0215	cysteine-tRNA ligase activity
IM697_RS03285	COG3842	ATPase activity
IM697_RS03345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_RS03350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_RS03420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IM697_RS03440	COG3300	MHYT domain
IM697_RS03440	COG5001	Diguanylate cyclase
IM697_RS03460	COG1105	Belongs to the carbohydrate kinase PfkB family
IM697_RS03510	COG1105	Belongs to the carbohydrate kinase PfkB family
IM697_RS03540	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IM697_RS03545	COG0463	Glycosyl transferase, family 2
IM697_RS03560	COG1278	Cold shock
IM697_RS03565	COG0459	protein refolding
IM697_RS03585	COG0667	Aldo Keto reductase
IM697_RS03590	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IM697_RS03595	COG1737	Transcriptional regulator
IM697_RS03640	COG3973	AAA domain
IM697_RS03650	COG1061	Type III restriction enzyme res subunit
IM697_RS03685	COG1278	Cold shock
IM697_RS03690	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IM697_RS03695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IM697_RS03705	COG2814	Major facilitator Superfamily
IM697_RS03715	COG0789	Transcriptional regulator
IM697_RS03775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM697_RS03785	COG2252	PERMEase
IM697_RS03825	COG0277	FAD linked oxidase domain protein
IM697_RS03830	COG2226	methyltransferase
IM697_RS03885	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IM697_RS03905	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IM697_RS03915	COG1609	Transcriptional regulator
IM697_RS03925	COG1175	transmembrane transport
IM697_RS03930	COG0395	ABC-type sugar transport system, permease component
IM697_RS03935	COG0277	FAD linked oxidase domain protein
IM697_RS03935	COG0247	lactate metabolic process
IM697_RS03940	COG4977	sequence-specific DNA binding
IM697_RS03950	COG0596	Alpha beta hydrolase
IM697_RS03950	COG2945	thiolester hydrolase activity
IM697_RS03975	COG5006	permease, DMT superfamily
IM697_RS03990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_RS04005	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS04010	COG1024	Enoyl-CoA hydratase
IM697_RS04020	COG0259	pyridoxamine-phosphate oxidase activity
IM697_RS04030	COG0515	serine threonine protein kinase
IM697_RS04030	COG2815	serine threonine protein kinase
IM697_RS04055	COG4821	SIS domain
IM697_RS04065	COG0596	Alpha beta hydrolase
IM697_RS04065	COG2945	thiolester hydrolase activity
IM697_RS04115	COG1595	DNA-templated transcription, initiation
IM697_RS04130	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS04135	COG1960	acyl-CoA dehydrogenase activity
IM697_RS04140	COG1960	acyl-CoA dehydrogenase activity
IM697_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS04160	COG1960	acyl-CoA dehydrogenase activity
IM697_RS04170	COG2267	carboxylic ester hydrolase activity
IM697_RS04335	COG1024	Enoyl-CoA hydratase
IM697_RS04345	COG1231	oxidoreductase activity
IM697_RS04350	COG2072	flavoprotein involved in K transport
IM697_RS04380	COG0259	pyridoxamine-phosphate oxidase activity
IM697_RS04395	COG1960	acyl-CoA dehydrogenase activity
IM697_RS04405	COG1280	lysine exporter protein (LysE YggA)
IM697_RS04410	COG1522	sequence-specific DNA binding
IM697_RS04415	COG1309	transcriptional regulator
IM697_RS04425	COG0515	serine threonine protein kinase
IM697_RS04425	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM697_RS04460	COG3629	intracellular signal transduction
IM697_RS04460	COG3903	Transcriptional regulator
IM697_RS04470	COG1215	transferase activity, transferring glycosyl groups
IM697_RS04480	COG0438	transferase activity, transferring glycosyl groups
IM697_RS04485	COG0463	Glycosyl transferase, family 2
IM697_RS04485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM697_RS04495	COG2197	response regulator
IM697_RS04550	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IM697_RS04575	COG1595	DNA-templated transcription, initiation
IM697_RS04650	COG1686	Belongs to the peptidase S11 family
IM697_RS04665	COG0386	Belongs to the glutathione peroxidase family
IM697_RS04700	COG0202	RNA polymerase activity
IM697_RS04740	COG1116	anion transmembrane transporter activity
IM697_RS04745	COG1131	(ABC) transporter
IM697_RS04755	COG2197	response regulator
IM697_RS04760	COG4585	Histidine kinase
IM697_RS04835	COG2018	Roadblock/LC7 domain
IM697_RS04850	COG1414	Transcriptional regulator
IM697_RS04870	COG1846	Transcriptional regulator
IM697_RS04875	COG3384	dioxygenase
IM697_RS04880	COG1247	-acetyltransferase
IM697_RS04900	COG0477	Major facilitator Superfamily
IM697_RS04905	COG1349	DNA-binding transcription factor activity
IM697_RS04915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM697_RS04915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM697_RS04915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM697_RS04930	COG1376	ErfK ybiS ycfS ynhG family protein
IM697_RS04935	COG3191	aminopeptidase activity
IM697_RS04950	COG1970	mechanosensitive ion channel activity
IM697_RS04960	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IM697_RS04970	COG0477	Major facilitator Superfamily
IM697_RS04985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IM697_RS04990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IM697_RS05000	COG0315	cyclic pyranopterin monophosphate synthase activity
IM697_RS05005	COG0521	Mo-molybdopterin cofactor biosynthetic process
IM697_RS05005	COG0315	cyclic pyranopterin monophosphate synthase activity
IM697_RS05010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_RS05030	COG0454	-acetyltransferase
IM697_RS05035	COG0708	Exodeoxyribonuclease III
IM697_RS05045	COG2072	flavoprotein involved in K transport
IM697_RS05050	COG2267	carboxylic ester hydrolase activity
IM697_RS05055	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS05065	COG0793	Belongs to the peptidase S41A family
IM697_RS05065	COG4946	Tricorn protease homolog
IM697_RS05075	COG2409	Drug exporters of the RND superfamily
IM697_RS05080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IM697_RS05115	COG0442	prolyl-tRNA aminoacylation
IM697_RS05120	COG1764	response to oxidative stress
IM697_RS05125	COG1846	Transcriptional regulator
IM697_RS05130	COG1122	ATPase activity
IM697_RS05140	COG0310	cobalt ion transport
IM697_RS05180	COG0084	hydrolase, TatD family'
IM697_RS05185	COG3584	3D domain protein
IM697_RS05185	COG3583	domain protein
IM697_RS05190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM697_RS05195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IM697_RS05205	COG0488	(ABC) transporter
IM697_RS05245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IM697_RS05260	COG2197	response regulator
IM697_RS05270	COG4106	trans-aconitate 2-methyltransferase activity
IM697_RS05285	COG1309	transcriptional regulator
IM697_RS05295	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IM697_RS05300	COG2826	transposase and inactivated derivatives, IS30 family
IM697_RS05315	COG0193	aminoacyl-tRNA hydrolase activity
IM697_RS05320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IM697_RS05325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM697_RS05330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IM697_RS05345	COG4585	Histidine kinase
IM697_RS05375	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_RS05395	COG0477	Major facilitator Superfamily
IM697_RS05400	COG1136	(ABC) transporter
IM697_RS05405	COG0577	efflux transmembrane transporter activity
IM697_RS05485	COG1652	LysM domain
IM697_RS05490	COG0148	phosphopyruvate hydratase activity
IM697_RS05510	COG1252	NADH dehydrogenase
IM697_RS05515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM697_RS05520	COG0577	efflux transmembrane transporter activity
IM697_RS05520	COG1136	(ABC) transporter
IM697_RS05525	COG1136	(ABC) transporter
IM697_RS05560	COG0183	Belongs to the thiolase family
IM697_RS05570	COG2755	lipolytic protein G-D-S-L family
IM697_RS05585	COG1174	glycine betaine transport
IM697_RS05590	COG1174	glycine betaine transport
IM697_RS05640	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IM697_RS05645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_RS05655	COG1228	amidohydrolase
IM697_RS05675	COG1191	sigma factor activity
IM697_RS05680	COG1366	Belongs to the anti-sigma-factor antagonist family
IM697_RS05710	COG3104	oligopeptide transport
IM697_RS05715	COG0745	RESPONSE REGULATOR receiver
IM697_RS05720	COG2205	protein histidine kinase activity
IM697_RS05760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IM697_RS05790	COG1316	TRANSCRIPTIONal
IM697_RS05805	COG1316	TRANSCRIPTIONal
IM697_RS05810	COG0463	Glycosyl transferase, family 2
IM697_RS05815	COG1316	TRANSCRIPTIONal
IM697_RS05820	COG1316	TRANSCRIPTIONal
IM697_RS05825	COG1316	TRANSCRIPTIONal
IM697_RS05850	COG0778	Nitroreductase
IM697_RS05850	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IM697_RS05855	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IM697_RS05890	COG1620	l-lactate permease
IM697_RS05895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM697_RS05900	COG2835	tetraacyldisaccharide 4'-kinase activity
IM697_RS05910	COG1482	cell wall glycoprotein biosynthetic process
IM697_RS05920	COG0681	Belongs to the peptidase S26 family
IM697_RS05925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM697_RS05925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM697_RS05925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM697_RS05930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IM697_RS05970	COG0714	Associated with various cellular activities
IM697_RS05990	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IM697_RS05995	COG0745	RESPONSE REGULATOR receiver
IM697_RS06000	COG5002	protein histidine kinase activity
IM697_RS06005	COG0823	Involved in the tonB-independent uptake of proteins
IM697_RS06015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM697_RS06020	COG2197	response regulator
IM697_RS06025	COG3214	Protein conserved in bacteria
IM697_RS06035	COG0653	protein targeting
IM697_RS06060	COG2902	Dehydrogenase
IM697_RS06065	COG1134	teichoic acid transport
IM697_RS06090	COG1846	Transcriptional regulator
IM697_RS06095	COG1764	response to oxidative stress
IM697_RS06100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM697_RS06100	COG0463	Glycosyl transferase, family 2
IM697_RS06105	COG0395	ABC-type sugar transport system, permease component
IM697_RS06110	COG1175	transmembrane transport
IM697_RS06125	COG0515	serine threonine protein kinase
IM697_RS06130	COG0515	serine threonine protein kinase
IM697_RS06135	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IM697_RS06150	COG2884	Cell division ATP-binding protein ftsE
IM697_RS06160	COG0793	Belongs to the peptidase S41A family
IM697_RS06165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IM697_RS06190	COG2027	D-alanyl-D-alanine carboxypeptidase
IM697_RS06200	COG1501	Belongs to the glycosyl hydrolase 31 family
IM697_RS06205	COG2124	cytochrome p450
IM697_RS06220	COG0583	DNA-binding transcription factor activity
IM697_RS06270	COG2223	nitrite transmembrane transporter activity
IM697_RS06295	COG3973	AAA domain
IM697_RS06305	COG0776	regulation of translation
IM697_RS06310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM697_RS06315	COG1678	Uncharacterized ACR, COG1678
IM697_RS06335	COG0395	ABC-type sugar transport system, permease component
IM697_RS06340	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IM697_RS06385	COG3654	unkown
IM697_RS06405	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_RS06430	COG1174	glycine betaine transport
IM697_RS06440	COG1174	glycine betaine transport
IM697_RS06450	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IM697_RS06460	COG0277	FAD linked oxidase domain protein
IM697_RS06495	COG1335	isochorismatase
IM697_RS06510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IM697_RS06520	COG1115	amino acid carrier protein
IM697_RS06520	COG1115	amino acid carrier protein
IM697_RS06525	COG1113	amino acid transport
IM697_RS06555	COG1263	PTS System
IM697_RS06560	COG1263	PTS System
IM697_RS06565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM697_RS06570	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IM697_RS06580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IM697_RS06620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_RS06635	COG1131	(ABC) transporter
IM697_RS06650	COG2733	membrane
IM697_RS06665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS06760	COG1074	ATP-dependent DNA helicase activity
IM697_RS06790	COG0270	DNA (cytosine-5-)-methyltransferase activity
IM697_RS06805	COG3415	Transposase
IM697_RS06805	COG2801	Transposase and inactivated derivatives
IM697_RS06825	COG3764	Sortase (surface protein transpeptidase)
IM697_RS06835	COG0706	membrane insertase activity
IM697_RS06845	COG4702	Belongs to the UPF0303 family
IM697_RS06850	COG0673	inositol 2-dehydrogenase activity
IM697_RS06920	COG3397	chitin binding
IM697_RS06925	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS06940	COG1126	abc transporter atp-binding protein
IM697_RS06945	COG0765	amino acid transport
IM697_RS06950	COG0765	amino acid transport
IM697_RS07000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IM697_RS07010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM697_RS07025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS07075	COG0406	alpha-ribazole phosphatase activity
IM697_RS07100	COG0745	RESPONSE REGULATOR receiver
IM697_RS07150	COG0589	response to stress
IM697_RS07160	COG4977	sequence-specific DNA binding
IM697_RS07165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IM697_RS07175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM697_RS07205	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IM697_RS07225	COG1960	acyl-CoA dehydrogenase activity
IM697_RS07240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_RS07245	COG1309	transcriptional regulator
IM697_RS07250	COG1525	nuclease
IM697_RS07260	COG1946	Acyl-CoA thioesterase
IM697_RS07280	COG0028	Belongs to the TPP enzyme family
IM697_RS07310	COG2356	endonuclease I
IM697_RS07345	COG1472	Belongs to the glycosyl hydrolase 3 family
IM697_RS07370	COG0456	acetyltransferase
IM697_RS07370	COG1846	Transcriptional regulator
IM697_RS07390	COG0673	inositol 2-dehydrogenase activity
IM697_RS07405	COG1609	Transcriptional regulator
IM697_RS07410	COG1129	ABC transporter
IM697_RS07420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS07425	COG1869	D-ribose catabolic process
IM697_RS07435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IM697_RS07460	COG2409	Drug exporters of the RND superfamily
IM697_RS07470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_RS07480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS07490	COG3962	Belongs to the TPP enzyme family
IM697_RS07550	COG0728	peptidoglycan biosynthetic process
IM697_RS07560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IM697_RS07565	COG0438	transferase activity, transferring glycosyl groups
IM697_RS07615	COG2304	oxidoreductase activity
IM697_RS07625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM697_RS07665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM697_RS07685	COG0629	single-stranded DNA binding
IM697_RS07715	COG2346	COG2346, Truncated hemoglobins
IM697_RS07765	COG1486	melibiose metabolic process
IM697_RS07770	COG0395	ABC-type sugar transport system, permease component
IM697_RS07775	COG1175	transmembrane transport
IM697_RS07785	COG1940	carbohydrate kinase activity
IM697_RS07795	COG0668	transmembrane transport
IM697_RS07810	COG1136	(ABC) transporter
IM697_RS07840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_RS07920	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IM697_RS07930	COG0584	glycerophosphoryl diester phosphodiesterase
IM697_RS07950	COG1349	DNA-binding transcription factor activity
IM697_RS07955	COG3842	ATPase activity
IM697_RS07960	COG0395	ABC-type sugar transport system, permease component
IM697_RS07965	COG1175	transmembrane transport
IM697_RS07970	COG1653	transport
IM697_RS07980	COG0588	phosphoglycerate mutase activity
IM697_RS07990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IM697_RS07995	COG1113	amino acid transport
IM697_RS08000	COG1268	BioY protein
IM697_RS08010	COG0515	serine threonine protein kinase
IM697_RS08015	COG1113	amino acid transport
IM697_RS08020	COG0698	ribose 5-phosphate isomerase
IM697_RS08035	COG4552	Acetyltransferase involved in intracellular survival and related
IM697_RS08050	COG3594	Acyltransferase
IM697_RS08075	COG0544	peptidyl-prolyl cis-trans isomerase activity
IM697_RS08080	COG0740	serine-type endopeptidase activity
IM697_RS08085	COG0740	serine-type endopeptidase activity
IM697_RS08090	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IM697_RS08100	COG0525	valine-tRNA ligase activity
IM697_RS08105	COG0285	dihydrofolate synthase activity
IM697_RS08115	COG0105	UTP biosynthetic process
IM697_RS08120	COG1077	Cell shape determining protein MreB Mrl
IM697_RS08135	COG0768	penicillin binding
IM697_RS08140	COG0772	Belongs to the SEDS family
IM697_RS08170	COG3387	PFAM Glycoside hydrolase 15-related
IM697_RS08175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IM697_RS08180	COG3265	gluconokinase activity
IM697_RS08190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IM697_RS08210	COG1530	ribonuclease E activity
IM697_RS08215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IM697_RS08220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IM697_RS08225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IM697_RS08230	COG3540	Alkaline phosphatase
IM697_RS08250	COG1215	transferase activity, transferring glycosyl groups
IM697_RS08260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IM697_RS08270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IM697_RS08285	COG0501	Belongs to the peptidase M48B family
IM697_RS08300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IM697_RS08310	COG0799	negative regulation of ribosome biogenesis
IM697_RS08315	COG0588	phosphoglycerate mutase activity
IM697_RS08335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IM697_RS08345	COG0495	leucyl-tRNA aminoacylation
IM697_RS08355	COG1307	EDD domain protein, DegV family
IM697_RS08360	COG1555	photosystem II stabilization
IM697_RS08360	COG1596	polysaccharide export
IM697_RS08375	COG2353	YceI-like domain
IM697_RS08395	COG0268	Binds directly to 16S ribosomal RNA
IM697_RS08400	COG0481	GTPase activity
IM697_RS08445	COG1420	regulation of RNA biosynthetic process
IM697_RS08450	COG0484	heat shock protein binding
IM697_RS08475	COG0793	Belongs to the peptidase S41A family
IM697_RS08475	COG4946	Tricorn protease homolog
IM697_RS08480	COG0537	adenosine 5'-monophosphoramidase activity
IM697_RS08485	COG1234	tRNA 3'-trailer cleavage
IM697_RS08490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_RS08505	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_RS08510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS08545	COG2315	Protein conserved in bacteria
IM697_RS08555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IM697_RS08565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IM697_RS08595	COG2801	Transposase and inactivated derivatives
IM697_RS08595	COG3415	Transposase
IM697_RS08605	COG2723	6-phospho-beta-galactosidase activity
IM697_RS08620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM697_RS08630	COG2409	Drug exporters of the RND superfamily
IM697_RS08635	COG4585	Histidine kinase
IM697_RS08640	COG2197	response regulator
IM697_RS08665	COG4608	Belongs to the ABC transporter superfamily
IM697_RS08680	COG0747	negative chemotaxis
IM697_RS08685	COG2186	Transcriptional regulator
IM697_RS08700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IM697_RS08715	COG1595	DNA-templated transcription, initiation
IM697_RS08740	COG0456	acetyltransferase
IM697_RS08805	COG1381	Involved in DNA repair and RecF pathway recombination
IM697_RS08810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM697_RS08825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM697_RS08830	COG1120	ATPase activity
IM697_RS08835	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM697_RS08835	COG3443	Belongs to the bacterial solute-binding protein 9 family
IM697_RS08840	COG0423	glycine-tRNA ligase activity
IM697_RS08850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM697_RS08850	COG0116	Belongs to the methyltransferase superfamily
IM697_RS08860	COG0667	Aldo Keto reductase
IM697_RS08875	COG0477	Major facilitator Superfamily
IM697_RS08905	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IM697_RS08910	COG1846	Transcriptional regulator
IM697_RS08910	COG1940	carbohydrate kinase activity
IM697_RS08915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM697_RS08915	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_RS08930	COG1051	belongs to the nudix hydrolase family
IM697_RS08940	COG0659	secondary active sulfate transmembrane transporter activity
IM697_RS08950	COG0745	RESPONSE REGULATOR receiver
IM697_RS08955	COG0642	Histidine kinase
IM697_RS08975	COG4221	oxidoreductase activity
IM697_RS08980	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS08985	COG1309	transcriptional regulator
IM697_RS08995	COG2146	nitrite reductase [NAD(P)H] activity
IM697_RS08995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM697_RS09000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM697_RS09030	COG1733	regulation of RNA biosynthetic process
IM697_RS09060	COG0243	molybdopterin cofactor binding
IM697_RS09075	COG2949	membrane
IM697_RS09090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IM697_RS09100	COG0358	DNA primase activity
IM697_RS09105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM697_RS09120	COG1070	Carbohydrate kinase
IM697_RS09175	COG0589	response to stress
IM697_RS09195	COG3290	protein histidine kinase activity
IM697_RS09200	COG4565	transcriptional regulatory protein
IM697_RS09210	COG1077	Cell shape determining protein MreB Mrl
IM697_RS09215	COG0515	serine threonine protein kinase
IM697_RS09215	COG2815	serine threonine protein kinase
IM697_RS09230	COG0825	malonyl-CoA metabolic process
IM697_RS09230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IM697_RS09235	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS09245	COG2186	Transcriptional regulator
IM697_RS09250	COG2801	Transposase and inactivated derivatives
IM697_RS09250	COG3415	Transposase
IM697_RS09290	COG2835	tetraacyldisaccharide 4'-kinase activity
IM697_RS09310	COG4981	capsule polysaccharide biosynthetic process
IM697_RS09360	COG1414	Transcriptional regulator
IM697_RS09365	COG3386	PFAM SMP-30 Gluconolaconase
IM697_RS09415	COG0395	ABC-type sugar transport system, permease component
IM697_RS09455	COG0477	Major facilitator Superfamily
IM697_RS09460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM697_RS09470	COG3507	Belongs to the glycosyl hydrolase 43 family
IM697_RS09475	COG3940	Belongs to the glycosyl hydrolase 43 family
IM697_RS09490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM697_RS09500	COG4214	carbohydrate transport
IM697_RS09505	COG1129	ABC transporter
IM697_RS09525	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_RS09535	COG1609	Transcriptional regulator
IM697_RS09540	COG1879	ABC-type sugar transport system periplasmic component
IM697_RS09550	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_RS09555	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_RS09565	COG2130	NADP-dependent
IM697_RS09570	COG1764	response to oxidative stress
IM697_RS09620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_RS09625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_RS09630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_RS09660	COG0789	Transcriptional regulator
IM697_RS09665	COG0667	Aldo Keto reductase
IM697_RS09680	COG1309	transcriptional regulator
IM697_RS09685	COG0477	Major facilitator Superfamily
IM697_RS09690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM697_RS09695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IM697_RS09740	COG1358	cellular component organization or biogenesis
IM697_RS09755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_RS09835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_RS09845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM697_RS09860	COG2259	Doxx family
IM697_RS09915	COG4122	O-methyltransferase activity
IM697_RS09950	COG0183	Belongs to the thiolase family
IM697_RS09955	COG2124	cytochrome p450
IM697_RS09975	COG3845	ABC transporter
IM697_RS09990	COG1657	PFAM Prenyltransferase squalene oxidase
IM697_RS09995	COG0251	oxidation-reduction process
IM697_RS10030	COG1309	transcriptional regulator
IM697_RS10035	COG0438	transferase activity, transferring glycosyl groups
IM697_RS10055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS10065	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM697_RS10130	COG2197	response regulator
IM697_RS10145	COG2030	dehydratase
IM697_RS10155	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS10170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IM697_RS10185	COG0800	Aldolase
IM697_RS10190	COG3022	response to hydroperoxide
IM697_RS10205	COG0789	Transcriptional regulator
IM697_RS10285	COG1201	RNA secondary structure unwinding
IM697_RS10320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM697_RS10350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IM697_RS10375	COG0745	RESPONSE REGULATOR receiver
IM697_RS10385	COG2259	Doxx family
IM697_RS10395	COG0667	Aldo Keto reductase
IM697_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS10405	COG3540	Alkaline phosphatase
IM697_RS10415	COG2814	Major facilitator Superfamily
IM697_RS10420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_RS10460	COG1120	ATPase activity
IM697_RS10465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS10515	COG1994	Peptidase M50
IM697_RS10535	COG2814	Major facilitator Superfamily
IM697_RS10550	COG0477	Major facilitator Superfamily
IM697_RS10555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IM697_RS10600	COG0174	glutamine synthetase
IM697_RS10625	COG0174	glutamine synthetase
IM697_RS10630	COG1017	nitric oxide dioxygenase activity
IM697_RS10630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM697_RS10635	COG1959	2 iron, 2 sulfur cluster binding
IM697_RS10655	COG0640	Transcriptional regulator
IM697_RS10660	COG0346	lactoylglutathione lyase activity
IM697_RS10685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IM697_RS10695	COG1609	Transcriptional regulator
IM697_RS10700	COG1653	transport
IM697_RS10705	COG1175	transmembrane transport
IM697_RS10710	COG3833	ABC-type maltose transport systems, permease component
IM697_RS10715	COG0366	Alpha amylase catalytic
IM697_RS10750	COG1309	transcriptional regulator
IM697_RS10785	COG2197	response regulator
IM697_RS10800	COG0745	RESPONSE REGULATOR receiver
IM697_RS10840	COG0501	Belongs to the peptidase M48B family
IM697_RS10850	COG0174	glutamine synthetase
IM697_RS10870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IM697_RS10875	COG0321	lipoyl(octanoyl) transferase activity
IM697_RS10890	COG1090	epimerase
IM697_RS10930	COG0733	neurotransmitter:sodium symporter activity
IM697_RS10940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IM697_RS10950	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM697_RS10955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM697_RS10960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM697_RS10985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IM697_RS10995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IM697_RS11015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_RS11020	COG2226	methyltransferase
IM697_RS11045	COG2197	response regulator
IM697_RS11050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM697_RS11055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IM697_RS11075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS11085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM697_RS11090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM697_RS11100	COG1376	ErfK ybiS ycfS ynhG family protein
IM697_RS11110	COG1845	cytochrome c oxidase, subunit III
IM697_RS11115	COG2010	Cytochrome c
IM697_RS11120	COG0723	plastoquinol--plastocyanin reductase activity
IM697_RS11125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM697_RS11130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IM697_RS11135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM697_RS11140	COG1929	Belongs to the glycerate kinase type-1 family
IM697_RS11150	COG0745	RESPONSE REGULATOR receiver
IM697_RS11155	COG2205	protein histidine kinase activity
IM697_RS11185	COG0791	NLP P60 protein
IM697_RS11230	COG0003	Pfam Anion-transporting ATPase
IM697_RS11240	COG1940	carbohydrate kinase activity
IM697_RS11275	COG0205	6-phosphofructokinase activity
IM697_RS11290	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IM697_RS11295	COG0243	molybdopterin cofactor binding
IM697_RS11300	COG2193	ferroxidase activity
IM697_RS11305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IM697_RS11315	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IM697_RS11320	COG2815	serine threonine protein kinase
IM697_RS11320	COG0515	serine threonine protein kinase
IM697_RS11325	COG2022	thiamine diphosphate biosynthetic process
IM697_RS11335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS11335	COG2022	thiamine diphosphate biosynthetic process
IM697_RS11355	COG0352	thiamine-phosphate diphosphorylase activity
IM697_RS11380	COG1309	transcriptional regulator
IM697_RS11390	COG1131	(ABC) transporter
IM697_RS11400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM697_RS11420	COG0714	Associated with various cellular activities
IM697_RS11430	COG0275	rRNA processing
IM697_RS11445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IM697_RS11455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM697_RS11460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM697_RS11470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM697_RS11475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IM697_RS11480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IM697_RS11485	COG1496	oxidoreductase activity
IM697_RS11495	COG1799	cell septum assembly
IM697_RS11505	COG3599	regulation of cell shape
IM697_RS11510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM697_RS11520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IM697_RS11580	COG0587	DNA-directed DNA polymerase activity
IM697_RS11590	COG1432	Conserved Protein
IM697_RS11610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IM697_RS11630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IM697_RS11635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM697_RS11640	COG0131	Imidazoleglycerol-phosphate dehydratase
IM697_RS11650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IM697_RS11655	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IM697_RS11660	COG0251	oxidation-reduction process
IM697_RS11665	COG0107	imidazoleglycerol-phosphate synthase activity
IM697_RS11685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IM697_RS11710	COG0134	indole-3-glycerol-phosphate synthase activity
IM697_RS11715	COG0133	tryptophan synthase activity
IM697_RS11720	COG0159	tryptophan synthase activity
IM697_RS11730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM697_RS11740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_RS11745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS11775	COG0070	glutamate synthase
IM697_RS11775	COG0067	glutamate synthase
IM697_RS11775	COG0069	glutamate synthase activity
IM697_RS11795	COG2304	oxidoreductase activity
IM697_RS11800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM697_RS11810	COG1960	acyl-CoA dehydrogenase activity
IM697_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS11820	COG1309	transcriptional regulator
IM697_RS11825	COG0183	Belongs to the thiolase family
IM697_RS11845	COG1024	Enoyl-CoA hydratase
IM697_RS11855	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS11865	COG5640	endopeptidase activity
IM697_RS11880	COG1605	Chorismate mutase
IM697_RS11880	COG0287	Prephenate dehydrogenase
IM697_RS11885	COG0745	RESPONSE REGULATOR receiver
IM697_RS11915	COG0737	Belongs to the 5'-nucleotidase family
IM697_RS11950	COG0411	ABC transporter
IM697_RS11970	COG2050	protein possibly involved in aromatic compounds catabolism
IM697_RS12005	COG1643	Atp-dependent helicase
IM697_RS12015	COG0539	negative regulation of cytoplasmic translation
IM697_RS12025	COG0237	dephospho-CoA kinase activity
IM697_RS12060	COG2267	carboxylic ester hydrolase activity
IM697_RS12065	COG1802	Transcriptional regulator
IM697_RS12070	COG1953	Uracil, thiamine, allantoin
IM697_RS12085	COG0251	oxidation-reduction process
IM697_RS12105	COG0402	S-adenosylhomocysteine deaminase activity
IM697_RS12160	COG3848	Pyruvate phosphate dikinase
IM697_RS12160	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_RS12165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_RS12170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_RS12205	COG0598	Magnesium transport protein CorA
IM697_RS12210	COG2226	methyltransferase
IM697_RS12215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS12220	COG2313	pseudouridylate synthase activity
IM697_RS12230	COG1063	alcohol dehydrogenase
IM697_RS12240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IM697_RS12245	COG0584	glycerophosphoryl diester phosphodiesterase
IM697_RS12255	COG0556	nucleotide-excision repair
IM697_RS12280	COG0387	Pfam Sodium calcium exchanger
IM697_RS12285	COG0477	Major facilitator Superfamily
IM697_RS12295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IM697_RS12300	COG1126	abc transporter atp-binding protein
IM697_RS12305	COG0765	amino acid transport
IM697_RS12310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_RS12325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IM697_RS12335	COG1609	Transcriptional regulator
IM697_RS12345	COG0322	excinuclease ABC activity
IM697_RS12350	COG1660	Displays ATPase and GTPase activities
IM697_RS12355	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IM697_RS12360	COG1481	regulation of sporulation
IM697_RS12370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM697_RS12375	COG0126	phosphoglycerate kinase activity
IM697_RS12380	COG0149	triose-phosphate isomerase activity
IM697_RS12385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM697_RS12400	COG0166	Belongs to the GPI family
IM697_RS12410	COG1136	(ABC) transporter
IM697_RS12415	COG1695	Transcriptional regulator
IM697_RS12420	COG1653	transport
IM697_RS12425	COG0366	Alpha amylase catalytic
IM697_RS12430	COG1653	transport
IM697_RS12435	COG1175	transmembrane transport
IM697_RS12440	COG0395	ABC-type sugar transport system, permease component
IM697_RS12445	COG0363	glucosamine-6-phosphate deaminase activity
IM697_RS12460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IM697_RS12470	COG0109	protoheme IX farnesyltransferase activity
IM697_RS12490	COG1612	heme a metabolic process
IM697_RS12520	COG0719	Fe-S assembly protein
IM697_RS12530	COG0396	ATPase activity
IM697_RS12535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM697_RS12540	COG0822	iron-sulfur transferase activity
IM697_RS12545	COG2151	metal-sulfur cluster biosynthetic enzyme
IM697_RS12565	COG1733	regulation of RNA biosynthetic process
IM697_RS12575	COG3226	Transcriptional regulator
IM697_RS12580	COG2171	N-acyltransferase activity
IM697_RS12590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_RS12645	COG1802	Transcriptional regulator
IM697_RS12655	COG1609	Transcriptional regulator
IM697_RS12665	COG1063	alcohol dehydrogenase
IM697_RS12690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM697_RS12695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_RS12725	COG1802	Transcriptional regulator
IM697_RS12730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_RS12740	COG1175	transmembrane transport
IM697_RS12745	COG0395	ABC-type sugar transport system, permease component
IM697_RS12750	COG3866	Pectate lyase
IM697_RS12765	COG3507	Belongs to the glycosyl hydrolase 43 family
IM697_RS12770	COG4677	pectinesterase activity
IM697_RS12780	COG2755	lipolytic protein G-D-S-L family
IM697_RS12785	COG3866	Pectate lyase
IM697_RS12790	COG4677	pectinesterase activity
IM697_RS12795	COG4677	pectinesterase activity
IM697_RS12810	COG4733	cellulase activity
IM697_RS12825	COG1595	DNA-templated transcription, initiation
IM697_RS12830	COG2252	PERMEase
IM697_RS12855	COG0768	penicillin binding
IM697_RS12860	COG2197	response regulator
IM697_RS12865	COG4585	Histidine kinase
IM697_RS12880	COG1414	Transcriptional regulator
IM697_RS12905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM697_RS12910	COG1595	DNA-templated transcription, initiation
IM697_RS12920	COG5285	phytanoyl-CoA dioxygenase
IM697_RS12925	COG1917	Cupin 2, conserved barrel domain protein
IM697_RS12930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM697_RS12935	COG0456	acetyltransferase
IM697_RS12940	COG2318	DinB family
IM697_RS12945	COG1104	cysteine desulfurase activity
IM697_RS12950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_RS12955	COG0765	amino acid transport
IM697_RS12960	COG1126	abc transporter atp-binding protein
IM697_RS13050	COG1492	cobalamin metabolic process
IM697_RS13055	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IM697_RS13075	COG0235	Class ii aldolase
IM697_RS13095	COG0488	(ABC) transporter
IM697_RS13145	COG3387	PFAM Glycoside hydrolase 15-related
IM697_RS13170	COG1966	Carbon starvation protein
IM697_RS13205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_RS13220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_RS13225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM697_RS13245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IM697_RS13255	COG0312	modulator of DNA gyrase
IM697_RS13275	COG2186	Transcriptional regulator
IM697_RS13280	COG2807	transmembrane transport
IM697_RS13295	COG0560	Phosphoserine phosphatase
IM697_RS13295	COG3830	Belongs to the UPF0237 family
IM697_RS13305	COG1131	(ABC) transporter
IM697_RS13305	COG0842	Transport permease protein
IM697_RS13305	COG1716	ATPase activity
IM697_RS13325	COG4221	oxidoreductase activity
IM697_RS13340	COG2197	response regulator
IM697_RS13355	COG1119	ATPase activity
IM697_RS13375	COG1881	PFAM PEBP family protein
IM697_RS13385	COG2094	Belongs to the DNA glycosylase MPG family
IM697_RS13420	COG0647	UMP catabolic process
IM697_RS13425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS13430	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS13435	COG1120	ATPase activity
IM697_RS13455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IM697_RS13460	COG0497	DNA recombination
IM697_RS13470	COG0297	glycogen (starch) synthase activity
IM697_RS13490	COG3387	PFAM Glycoside hydrolase 15-related
IM697_RS13495	COG0504	CTP synthase activity
IM697_RS13500	COG0494	nUDIX hydrolase
IM697_RS13510	COG0686	Belongs to the AlaDH PNT family
IM697_RS13525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IM697_RS13530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IM697_RS13535	COG1187	pseudouridine synthase activity
IM697_RS13550	COG0477	Major facilitator Superfamily
IM697_RS13555	COG0494	nUDIX hydrolase
IM697_RS13590	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IM697_RS13600	COG1160	GTP binding
IM697_RS13615	COG1652	LysM domain
IM697_RS13620	COG3583	domain protein
IM697_RS13630	COG0411	ABC transporter
IM697_RS13670	COG0671	phosphoesterase, PA-phosphatase related
IM697_RS13675	COG0477	Major facilitator Superfamily
IM697_RS13680	COG1960	acyl-CoA dehydrogenase activity
IM697_RS13685	COG1799	cell septum assembly
IM697_RS13700	COG0330	HflC and HflK could
IM697_RS13715	COG0587	DNA-directed DNA polymerase activity
IM697_RS13720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM697_RS13755	COG2226	methyltransferase
IM697_RS13770	COG1725	Transcriptional regulator
IM697_RS13795	COG1649	PFAM Uncharacterised BCR, COG1649
IM697_RS13795	COG0726	polysaccharide deacetylase
IM697_RS13825	COG2755	lipolytic protein G-D-S-L family
IM697_RS13830	COG2815	serine threonine protein kinase
IM697_RS13830	COG0515	serine threonine protein kinase
IM697_RS13850	COG1595	DNA-templated transcription, initiation
IM697_RS13885	COG2188	Transcriptional regulator
IM697_RS13890	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IM697_RS13900	COG1309	transcriptional regulator
IM697_RS13905	COG0243	molybdopterin cofactor binding
IM697_RS13910	COG2851	Citrate transporter
IM697_RS13945	COG0477	Major facilitator Superfamily
IM697_RS13950	COG0697	spore germination
IM697_RS13955	COG0640	Transcriptional regulator
IM697_RS13965	COG1960	acyl-CoA dehydrogenase activity
IM697_RS13985	COG0789	Transcriptional regulator
IM697_RS14015	COG3876	Protein conserved in bacteria
IM697_RS14020	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS14025	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS14035	COG2197	response regulator
IM697_RS14040	COG4585	Histidine kinase
IM697_RS14075	COG2149	membrane
IM697_RS14080	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IM697_RS14120	COG1063	alcohol dehydrogenase
IM697_RS14125	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS14135	COG3265	gluconokinase activity
IM697_RS14140	COG2186	Transcriptional regulator
IM697_RS14145	COG3012	SEC-C Motif Domain Protein
IM697_RS14150	COG0308	aminopeptidase N
IM697_RS14200	COG0667	Aldo Keto reductase
IM697_RS14205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS14215	COG0598	Magnesium transport protein CorA
IM697_RS14220	COG0588	phosphoglycerate mutase activity
IM697_RS14235	COG0215	cysteine-tRNA ligase activity
IM697_RS14245	COG1404	Belongs to the peptidase S8 family
IM697_RS14245	COG4935	Belongs to the peptidase S8 family
IM697_RS14260	COG2186	Transcriptional regulator
IM697_RS14265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM697_RS14270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM697_RS14275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IM697_RS14280	COG1414	Transcriptional regulator
IM697_RS14285	COG0646	methionine synthase
IM697_RS14285	COG1410	methionine synthase
IM697_RS14295	COG0747	negative chemotaxis
IM697_RS14300	COG0747	negative chemotaxis
IM697_RS14305	COG2197	response regulator
IM697_RS14315	COG0517	IMP dehydrogenase activity
IM697_RS14315	COG1994	Peptidase M50
IM697_RS14335	COG1222	aaa ATPase
IM697_RS14340	COG4122	O-methyltransferase activity
IM697_RS14355	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IM697_RS14360	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IM697_RS14365	COG1609	Transcriptional regulator
IM697_RS14375	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IM697_RS14410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM697_RS14415	COG0805	protein transport
IM697_RS14425	COG3973	AAA domain
IM697_RS14460	COG0564	pseudouridine synthase activity
IM697_RS14470	COG2124	cytochrome p450
IM697_RS14480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM697_RS14485	COG4175	Glycine betaine
IM697_RS14485	COG0517	IMP dehydrogenase activity
IM697_RS14490	COG4176	ABC-type proline glycine betaine transport system permease component
IM697_RS14500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM697_RS14515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IM697_RS14520	COG0531	amino acid
IM697_RS14530	COG0174	glutamine synthetase
IM697_RS14535	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS14580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IM697_RS14585	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IM697_RS14590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IM697_RS14595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM697_RS14600	COG5002	protein histidine kinase activity
IM697_RS14605	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IM697_RS14610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM697_RS14610	COG0072	phenylalanine-tRNA ligase activity
IM697_RS14640	COG1649	PFAM Uncharacterised BCR, COG1649
IM697_RS14650	COG0697	spore germination
IM697_RS14680	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IM697_RS14685	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IM697_RS14690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM697_RS14695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM697_RS14700	COG1438	arginine binding
IM697_RS14735	COG0165	Argininosuccinate lyase
IM697_RS14750	COG0477	Major facilitator Superfamily
IM697_RS14755	COG0714	Associated with various cellular activities
IM697_RS14765	COG2304	oxidoreductase activity
IM697_RS14770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_RS14775	COG0745	RESPONSE REGULATOR receiver
IM697_RS14780	COG2205	protein histidine kinase activity
IM697_RS14785	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS14785	COG0204	Acyl-transferase
IM697_RS14820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IM697_RS14825	COG2011	ABC-type metal ion transport system permease component
IM697_RS14830	COG1464	Belongs to the NlpA lipoprotein family
IM697_RS14845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IM697_RS14850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM697_RS14850	COG1648	precorrin-2 dehydrogenase activity
IM697_RS14860	COG0494	nUDIX hydrolase
IM697_RS14915	COG0512	Glutamine amidotransferase of anthranilate synthase
IM697_RS14915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM697_RS14925	COG0456	acetyltransferase
IM697_RS14970	COG1175	transmembrane transport
IM697_RS14975	COG0395	ABC-type sugar transport system, permease component
IM697_RS15005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM697_RS15020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IM697_RS15025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM697_RS15045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IM697_RS15050	COG1560	Kdo2-lipid A biosynthetic process
IM697_RS15055	COG0438	transferase activity, transferring glycosyl groups
IM697_RS15065	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IM697_RS15070	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IM697_RS15075	COG0217	transcriptional regulatory protein
IM697_RS15080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IM697_RS15085	COG0632	four-way junction helicase activity
IM697_RS15090	COG2255	four-way junction helicase activity
IM697_RS15100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM697_RS15105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM697_RS15110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM697_RS15115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM697_RS15120	COG1196	nuclear chromosome segregation
IM697_RS15125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM697_RS15135	COG0124	histidyl-tRNA synthetase
IM697_RS15150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IM697_RS15170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IM697_RS15175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IM697_RS15180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM697_RS15185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM697_RS15195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IM697_RS15200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IM697_RS15205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IM697_RS15215	COG0006	proline dipeptidase activity
IM697_RS15220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM697_RS15225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM697_RS15235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IM697_RS15240	COG0540	Belongs to the ATCase OTCase family
IM697_RS15245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM697_RS15255	COG0505	Belongs to the CarA family
IM697_RS15260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IM697_RS15265	COG0167	dihydroorotate dehydrogenase activity
IM697_RS15270	COG0284	orotidine-5'-phosphate decarboxylase activity
IM697_RS15280	COG0194	GDP metabolic process
IM697_RS15285	COG1758	RNA polymerase activity
IM697_RS15295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IM697_RS15330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM697_RS15340	COG2409	Drug exporters of the RND superfamily
IM697_RS15345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM697_RS15350	COG2390	Transcriptional regulator
IM697_RS15360	COG3629	intracellular signal transduction
IM697_RS15360	COG3903	Transcriptional regulator
IM697_RS15380	COG0531	amino acid
IM697_RS15395	COG2188	Transcriptional regulator
IM697_RS15405	COG1176	ABC-type spermidine putrescine transport system, permease component I
IM697_RS15415	COG3842	ATPase activity
IM697_RS15420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_RS15435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM697_RS15475	COG5002	protein histidine kinase activity
IM697_RS15480	COG0745	RESPONSE REGULATOR receiver
IM697_RS15510	COG1846	Transcriptional regulator
IM697_RS15510	COG1940	carbohydrate kinase activity
IM697_RS15515	COG1090	epimerase
IM697_RS15530	COG3201	nicotinamide mononucleotide transporter
IM697_RS15535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_RS15535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_RS15540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IM697_RS15545	COG0140	phosphoribosyl-ATP diphosphatase activity
IM697_RS15550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IM697_RS15610	COG1960	acyl-CoA dehydrogenase activity
IM697_RS15640	COG1216	Glycosyl transferase, family 2
IM697_RS15645	COG3030	protein affecting phage T7 exclusion by the F plasmid
IM697_RS15655	COG2270	Major facilitator Superfamily
IM697_RS15665	COG2364	Membrane
IM697_RS15670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_RS15700	COG0438	transferase activity, transferring glycosyl groups
IM697_RS15710	COG1984	allophanate hydrolase subunit 2
IM697_RS15715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IM697_RS15720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IM697_RS15725	COG4336	lyase activity
IM697_RS15730	COG2814	Major facilitator Superfamily
IM697_RS15785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM697_RS15790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IM697_RS15800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_RS15820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM697_RS15830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM697_RS15860	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IM697_RS15880	COG1716	ATPase activity
IM697_RS15900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM697_RS15910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM697_RS15910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM697_RS15945	COG1175	transmembrane transport
IM697_RS15950	COG0395	ABC-type sugar transport system, permease component
IM697_RS15975	COG4941	Belongs to the sigma-70 factor family
IM697_RS15980	COG3795	YCII-related domain
IM697_RS16000	COG4106	trans-aconitate 2-methyltransferase activity
IM697_RS16055	COG0697	spore germination
IM697_RS16060	COG0583	DNA-binding transcription factor activity
IM697_RS16100	COG0747	negative chemotaxis
IM697_RS16105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM697_RS16120	COG2318	DinB family
IM697_RS16140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IM697_RS16155	COG1968	undecaprenyl-diphosphatase activity
IM697_RS16175	COG0183	Belongs to the thiolase family
IM697_RS16210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IM697_RS16235	COG0110	maltose O-acetyltransferase activity
IM697_RS16260	COG0640	Transcriptional regulator
IM697_RS16270	COG1832	CoA-binding protein
IM697_RS16305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM697_RS16320	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IM697_RS16335	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS16340	COG4175	Glycine betaine
IM697_RS16340	COG0517	IMP dehydrogenase activity
IM697_RS16345	COG4176	ABC-type proline glycine betaine transport system permease component
IM697_RS16355	COG1802	Transcriptional regulator
IM697_RS16360	COG2181	nitrate reductase activity
IM697_RS16360	COG0247	lactate metabolic process
IM697_RS16365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IM697_RS16370	COG2086	electron transfer activity
IM697_RS16380	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM697_RS16410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS16415	COG4638	Rieske (2fe-2S)
IM697_RS16420	COG3290	protein histidine kinase activity
IM697_RS16430	COG0509	glycine decarboxylation via glycine cleavage system
IM697_RS16435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_RS16440	COG1760	l-serine dehydratase
IM697_RS16445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM697_RS16450	COG0438	transferase activity, transferring glycosyl groups
IM697_RS16455	COG0215	cysteine-tRNA ligase activity
IM697_RS16465	COG1739	Uncharacterized protein family UPF0029
IM697_RS16480	COG0420	3'-5' exonuclease activity
IM697_RS16485	COG0419	ATPase involved in DNA repair
IM697_RS16505	COG0745	RESPONSE REGULATOR receiver
IM697_RS16510	COG2205	protein histidine kinase activity
IM697_RS16515	COG1522	sequence-specific DNA binding
IM697_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS16545	COG0626	cystathionine gamma-synthase activity
IM697_RS16570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_RS16615	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IM697_RS16615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS16630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IM697_RS16635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM697_RS16660	COG0475	glutathione-regulated potassium exporter activity
IM697_RS16680	COG1595	DNA-templated transcription, initiation
IM697_RS16685	COG2188	Transcriptional regulator
IM697_RS16690	COG1940	carbohydrate kinase activity
IM697_RS16695	COG2197	response regulator
IM697_RS16700	COG4585	Histidine kinase
IM697_RS16720	COG3663	DNA glycosylase
IM697_RS16725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM697_RS16750	COG0456	acetyltransferase
IM697_RS16760	COG1136	(ABC) transporter
IM697_RS16760	COG0577	efflux transmembrane transporter activity
IM697_RS16765	COG0577	efflux transmembrane transporter activity
IM697_RS16765	COG1136	(ABC) transporter
IM697_RS16780	COG2226	methyltransferase
IM697_RS16795	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IM697_RS16800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM697_RS16805	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IM697_RS16830	COG0583	DNA-binding transcription factor activity
IM697_RS16835	COG1280	lysine exporter protein (LysE YggA)
IM697_RS16850	COG0740	serine-type endopeptidase activity
IM697_RS16865	COG1309	transcriptional regulator
IM697_RS16870	COG0831	urea catabolic process
IM697_RS16875	COG0832	Belongs to the urease beta subunit family
IM697_RS16880	COG0804	urea catabolic process
IM697_RS16890	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IM697_RS16895	COG0829	nickel cation binding
IM697_RS16915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM697_RS16920	COG1834	amidinotransferase
IM697_RS16925	COG1522	sequence-specific DNA binding
IM697_RS16930	COG3279	Response regulator of the LytR AlgR family
IM697_RS16940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_RS16945	COG3275	phosphorelay sensor kinase activity
IM697_RS16955	COG0515	serine threonine protein kinase
IM697_RS16955	COG2815	serine threonine protein kinase
IM697_RS16970	COG0205	6-phosphofructokinase activity
IM697_RS16975	COG3442	glutamine amidotransferase
IM697_RS16985	COG0242	peptide deformylase activity
IM697_RS16995	COG1960	acyl-CoA dehydrogenase activity
IM697_RS17005	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS17015	COG1793	dna ligase
IM697_RS17020	COG0492	ferredoxin-NADP+ reductase activity
IM697_RS17035	COG1960	acyl-CoA dehydrogenase activity
IM697_RS17040	COG1960	acyl-CoA dehydrogenase activity
IM697_RS17075	COG3903	Transcriptional regulator
IM697_RS17075	COG3629	intracellular signal transduction
IM697_RS17100	COG0586	Pfam SNARE associated Golgi protein
IM697_RS17105	COG4214	carbohydrate transport
IM697_RS17115	COG4213	ABC transporter substrate-binding protein
IM697_RS17125	COG4213	ABC transporter substrate-binding protein
IM697_RS17150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS17170	COG1082	Xylose isomerase domain protein TIM barrel
IM697_RS17205	COG3693	PFAM glycoside hydrolase, family 10
IM697_RS17220	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS17250	COG1846	Transcriptional regulator
IM697_RS17250	COG1940	carbohydrate kinase activity
IM697_RS17280	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM697_RS17315	COG0642	Histidine kinase
IM697_RS17340	COG2018	Roadblock/LC7 domain
IM697_RS17350	COG1946	Acyl-CoA thioesterase
IM697_RS17365	COG0254	rRNA binding
IM697_RS17380	COG1132	(ABC) transporter
IM697_RS17385	COG1132	(ABC) transporter
IM697_RS17410	COG1132	(ABC) transporter
IM697_RS17420	COG2072	flavoprotein involved in K transport
IM697_RS17425	COG0432	Pfam Uncharacterised protein family UPF0047
IM697_RS17510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS17515	COG1120	ATPase activity
IM697_RS17520	COG2814	Major facilitator Superfamily
IM697_RS17525	COG0367	asparagine synthase
IM697_RS17545	COG0277	FAD linked oxidase domain protein
IM697_RS17575	COG1082	Xylose isomerase domain protein TIM barrel
IM697_RS17580	COG0673	inositol 2-dehydrogenase activity
IM697_RS17590	COG1609	Transcriptional regulator
IM697_RS17600	COG0791	NLP P60 protein
IM697_RS17600	COG0741	lytic transglycosylase activity
IM697_RS17610	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_RS17615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_RS17620	COG0395	ABC-type sugar transport system, permease component
IM697_RS17625	COG1175	transmembrane transport
IM697_RS17630	COG1653	transport
IM697_RS17660	COG1222	aaa ATPase
IM697_RS17735	COG3396	Phenylacetate-CoA oxygenase
IM697_RS17740	COG3460	Phenylacetate-CoA oxygenase
IM697_RS17745	COG3396	Phenylacetate-CoA oxygenase
IM697_RS17750	COG2151	metal-sulfur cluster biosynthetic enzyme
IM697_RS17755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM697_RS17785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_RS17800	COG2706	6-phosphogluconolactonase activity
IM697_RS17810	COG2971	BadF BadG BcrA BcrD
IM697_RS17815	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM697_RS17830	COG1960	acyl-CoA dehydrogenase activity
IM697_RS17850	COG3509	depolymerase
IM697_RS17855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM697_RS17860	COG1902	pentaerythritol trinitrate reductase activity
IM697_RS17865	COG0640	Transcriptional regulator
IM697_RS17875	COG0493	'glutamate synthase
IM697_RS17895	COG1309	transcriptional regulator
IM697_RS17900	COG0546	phosphoglycolate phosphatase activity
IM697_RS17905	COG0671	phosphoesterase, PA-phosphatase related
IM697_RS17935	COG0584	glycerophosphoryl diester phosphodiesterase
IM697_RS17960	COG0583	DNA-binding transcription factor activity
IM697_RS17970	COG0204	Acyl-transferase
IM697_RS17995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IM697_RS18010	COG0515	serine threonine protein kinase
IM697_RS18220	COG0494	nUDIX hydrolase
IM697_RS18280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM697_RS18290	COG0105	UTP biosynthetic process
IM697_RS18675	COG3345	alpha-galactosidase
IM697_RS18680	COG1090	epimerase
IM697_RS18690	COG1660	Displays ATPase and GTPase activities
IM697_RS18720	COG4585	Histidine kinase
IM697_RS18725	COG2197	response regulator
IM697_RS18755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM697_RS18780	COG2223	nitrite transmembrane transporter activity
IM697_RS18790	COG0673	inositol 2-dehydrogenase activity
IM697_RS18800	COG2197	response regulator
IM697_RS18805	COG4585	Histidine kinase
IM697_RS18850	COG3594	Acyltransferase
IM697_RS18880	COG0326	Molecular chaperone. Has ATPase activity
IM697_RS18895	COG0019	diaminopimelate decarboxylase activity
IM697_RS18900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM697_RS18905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM697_RS18925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM697_RS18925	COG1796	DNA polymerase
IM697_RS18950	COG1653	transport
IM697_RS18955	COG1175	transmembrane transport
IM697_RS18960	COG0395	ABC-type sugar transport system, permease component
IM697_RS18980	COG2608	mercury ion transmembrane transporter activity
IM697_RS18990	COG3387	PFAM Glycoside hydrolase 15-related
IM697_RS18995	COG1349	DNA-binding transcription factor activity
IM697_RS19000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM697_RS19010	COG2813	Specifically methylates the guanine in position
IM697_RS19020	COG1940	carbohydrate kinase activity
IM697_RS19045	COG1136	(ABC) transporter
IM697_RS19050	COG0577	efflux transmembrane transporter activity
IM697_RS19075	COG1349	DNA-binding transcription factor activity
IM697_RS19110	COG1215	transferase activity, transferring glycosyl groups
IM697_RS19140	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS19170	COG0142	geranyltranstransferase activity
IM697_RS19215	COG3848	Pyruvate phosphate dikinase
IM697_RS19215	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_RS19275	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IM697_RS19275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IM697_RS19280	COG0726	polysaccharide deacetylase
IM697_RS19325	COG0583	DNA-binding transcription factor activity
IM697_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS19340	COG0583	DNA-binding transcription factor activity
IM697_RS19350	COG1053	succinate dehydrogenase
IM697_RS19355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM697_RS19380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS19385	COG0277	FAD linked oxidase domain protein
IM697_RS19390	COG2197	response regulator
IM697_RS19395	COG0523	cobalamin synthesis protein
IM697_RS19405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_RS19420	COG3360	Dodecin
IM697_RS19425	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IM697_RS19430	COG0121	glutamine amidotransferase
IM697_RS19435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM697_RS19490	COG0745	RESPONSE REGULATOR receiver
IM697_RS19495	COG5002	protein histidine kinase activity
IM697_RS19500	COG2358	TRAP transporter, solute receptor (TAXI family
IM697_RS19505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IM697_RS19555	COG0583	DNA-binding transcription factor activity
IM697_RS19570	COG2182	Extracellular solute-binding protein
IM697_RS19580	COG3833	ABC-type maltose transport systems, permease component
IM697_RS19670	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS19715	COG2610	gluconate transmembrane transporter activity
IM697_RS19720	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_RS19740	COG2353	YceI-like domain
IM697_RS19745	COG1454	alcohol dehydrogenase
IM697_RS19750	COG3485	protocatechuate 3,4-dioxygenase
IM697_RS19760	COG3284	Transcriptional regulator
IM697_RS19795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_RS19820	COG2814	Major facilitator Superfamily
IM697_RS19840	COG0583	DNA-binding transcription factor activity
IM697_RS19855	COG1609	Transcriptional regulator
IM697_RS19870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM697_RS19880	COG0242	peptide deformylase activity
IM697_RS19930	COG3507	Belongs to the glycosyl hydrolase 43 family
IM697_RS19965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_RS19970	COG3345	alpha-galactosidase
IM697_RS19990	COG2124	cytochrome p450
IM697_RS19990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM697_RS20000	COG2072	flavoprotein involved in K transport
IM697_RS20005	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS20010	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS20025	COG1595	DNA-templated transcription, initiation
IM697_RS20030	COG2409	Drug exporters of the RND superfamily
IM697_RS20055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM697_RS20065	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS20075	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IM697_RS20095	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS20100	COG1007	ATP synthesis coupled electron transport
IM697_RS20120	COG2135	peptidase activity
IM697_RS20130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IM697_RS20145	COG1609	Transcriptional regulator
IM697_RS20180	COG0604	alcohol dehydrogenase
IM697_RS20180	COG3321	synthase
IM697_RS20190	COG0542	response to heat
IM697_RS20200	COG0577	efflux transmembrane transporter activity
IM697_RS20200	COG1136	(ABC) transporter
IM697_RS20205	COG0723	plastoquinol--plastocyanin reductase activity
IM697_RS20205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS20210	COG1556	Lactate utilization protein
IM697_RS20215	COG1139	Iron-sulfur cluster binding protein
IM697_RS20220	COG0247	lactate metabolic process
IM697_RS20225	COG1070	Carbohydrate kinase
IM697_RS20230	COG3347	Dehydrogenase
IM697_RS20230	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS20240	COG1129	ABC transporter
IM697_RS20270	COG1609	Transcriptional regulator
IM697_RS20285	COG1595	DNA-templated transcription, initiation
IM697_RS20295	COG1357	PFAM Pentapeptide repeats (8 copies)
IM697_RS20310	COG2706	6-phosphogluconolactonase activity
IM697_RS20395	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM697_RS20395	COG1796	DNA polymerase
IM697_RS20425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM697_RS20435	COG1846	Transcriptional regulator
IM697_RS20495	COG0531	amino acid
IM697_RS20515	COG0435	Glutathione S-transferase
IM697_RS20535	COG2124	cytochrome p450
IM697_RS20555	COG3415	Transposase
IM697_RS20555	COG2801	Transposase and inactivated derivatives
IM697_RS20565	COG0667	Aldo Keto reductase
IM697_RS20595	COG3250	beta-galactosidase activity
IM697_RS20610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM697_RS20635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM697_RS20755	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IM697_RS20755	COG3608	succinylglutamate desuccinylase aspartoacylase
IM697_RS20795	COG0789	Transcriptional regulator
IM697_RS20825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM697_RS20850	COG0019	diaminopimelate decarboxylase activity
IM697_RS20860	COG2814	Major facilitator Superfamily
IM697_RS20875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM697_RS20880	COG1120	ATPase activity
IM697_RS20885	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS20890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS20900	COG1132	(ABC) transporter
IM697_RS20905	COG1937	Protein conserved in bacteria
IM697_RS20925	COG4221	oxidoreductase activity
IM697_RS20950	COG2182	Extracellular solute-binding protein
IM697_RS20955	COG0395	ABC-type sugar transport system, permease component
IM697_RS20960	COG1175	transmembrane transport
IM697_RS20965	COG1846	Transcriptional regulator
IM697_RS20965	COG1940	carbohydrate kinase activity
IM697_RS21040	COG1940	carbohydrate kinase activity
IM697_RS21050	COG1175	transmembrane transport
IM697_RS21055	COG0395	ABC-type sugar transport system, permease component
IM697_RS21070	COG1072	(Pantothenic acid kinase))
IM697_RS21080	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IM697_RS21085	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IM697_RS21140	COG0673	inositol 2-dehydrogenase activity
IM697_RS21150	COG3250	beta-galactosidase activity
IM697_RS21160	COG1175	transmembrane transport
IM697_RS21170	COG1609	Transcriptional regulator
IM697_RS21180	COG0438	transferase activity, transferring glycosyl groups
IM697_RS21190	COG0702	epimerase
IM697_RS21265	COG3290	protein histidine kinase activity
IM697_RS21285	COG2264	protein methyltransferase activity
IM697_RS21290	COG1132	(ABC) transporter
IM697_RS21315	COG3739	integral membrane protein
IM697_RS21360	COG2186	Transcriptional regulator
IM697_RS21365	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_RS21375	COG0800	Aldolase
IM697_RS21405	COG1396	sequence-specific DNA binding
IM697_RS21430	COG2124	cytochrome p450
IM697_RS21435	COG2070	2-Nitropropane dioxygenase
IM697_RS21450	COG2267	carboxylic ester hydrolase activity
IM697_RS21460	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM697_RS21475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_RS21500	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM697_RS21510	COG4941	Belongs to the sigma-70 factor family
IM697_RS21540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM697_RS21585	COG0187	DNA topoisomerase II activity
IM697_RS21630	COG0583	DNA-binding transcription factor activity
IM697_RS21645	COG4106	trans-aconitate 2-methyltransferase activity
IM697_RS21685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM697_RS21735	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IM697_RS21755	COG0395	ABC-type sugar transport system, permease component
IM697_RS21760	COG1175	transmembrane transport
IM697_RS21765	COG1653	transport
IM697_RS21775	COG2186	Transcriptional regulator
IM697_RS21800	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IM697_RS21805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IM697_RS21805	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IM697_RS21810	COG3639	organic phosphonate transmembrane transporter activity
IM697_RS21830	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS21850	COG0733	neurotransmitter:sodium symporter activity
IM697_RS21860	COG0277	FAD linked oxidase domain protein
IM697_RS21860	COG0247	lactate metabolic process
IM697_RS21910	COG0659	secondary active sulfate transmembrane transporter activity
IM697_RS21915	COG4977	sequence-specific DNA binding
IM697_RS21960	COG1131	(ABC) transporter
IM697_RS21995	COG0148	phosphopyruvate hydratase activity
IM697_RS22015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IM697_RS22020	COG1349	DNA-binding transcription factor activity
IM697_RS22060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IM697_RS22065	COG0071	Belongs to the small heat shock protein (HSP20) family
IM697_RS22105	COG0577	efflux transmembrane transporter activity
IM697_RS22105	COG1136	(ABC) transporter
IM697_RS22135	COG1595	DNA-templated transcription, initiation
IM697_RS22160	COG1595	DNA-templated transcription, initiation
IM697_RS22165	COG0604	alcohol dehydrogenase
IM697_RS22190	COG0596	Alpha beta hydrolase
IM697_RS22205	COG2226	methyltransferase
IM697_RS22255	COG1621	beta-fructofuranosidase activity
IM697_RS22265	COG1609	Transcriptional regulator
IM697_RS22275	COG1175	transmembrane transport
IM697_RS22310	COG0395	ABC-type sugar transport system, permease component
IM697_RS22330	COG0657	acetylesterase activity
IM697_RS22350	COG0473	3-isopropylmalate dehydrogenase activity
IM697_RS22370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM697_RS22390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS22405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IM697_RS22410	COG1725	Transcriptional regulator
IM697_RS22435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IM697_RS22480	COG2188	Transcriptional regulator
IM697_RS22505	COG2223	nitrite transmembrane transporter activity
IM697_RS22515	COG0702	epimerase
IM697_RS22540	COG0586	Pfam SNARE associated Golgi protein
IM697_RS22545	COG4585	Histidine kinase
IM697_RS22605	COG2409	Drug exporters of the RND superfamily
IM697_RS22615	COG2205	protein histidine kinase activity
IM697_RS22620	COG0745	RESPONSE REGULATOR receiver
IM697_RS22655	COG3328	transposase activity
IM697_RS22770	COG2815	serine threonine protein kinase
IM697_RS22770	COG0515	serine threonine protein kinase
IM697_RS22785	COG2815	serine threonine protein kinase
IM697_RS22785	COG0515	serine threonine protein kinase
IM697_RS22820	COG3328	transposase activity
IM697_RS22865	COG1335	isochorismatase
IM697_RS22885	COG4585	Histidine kinase
IM697_RS22900	COG2311	Membrane
IM697_RS22905	COG2311	Membrane
IM697_RS22915	COG4585	Histidine kinase
IM697_RS22920	COG2197	response regulator
IM697_RS22960	COG2311	Membrane
IM697_RS22970	COG1404	Belongs to the peptidase S8 family
IM697_RS22975	COG4585	Histidine kinase
IM697_RS22980	COG2197	response regulator
IM697_RS22990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_RS23005	COG2311	Membrane
IM697_RS23030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_RS23040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_RS23055	COG0154	amidase activity
IM697_RS23060	COG4166	transmembrane transport
IM697_RS23065	COG0601	transmembrane transport
IM697_RS23070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_RS23110	COG3507	Belongs to the glycosyl hydrolase 43 family
IM697_RS23115	COG1874	Beta-galactosidase
IM697_RS23125	COG3328	transposase activity
IM697_RS23135	COG1175	transmembrane transport
IM697_RS23140	COG0395	ABC-type sugar transport system, permease component
IM697_RS23165	COG0673	inositol 2-dehydrogenase activity
IM697_RS23170	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_RS23175	COG1879	ABC-type sugar transport system periplasmic component
IM697_RS23190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_RS23210	COG0247	lactate metabolic process
IM697_RS23210	COG0277	FAD linked oxidase domain protein
IM697_RS23215	COG0583	DNA-binding transcription factor activity
IM697_RS23225	COG0531	amino acid
IM697_RS23250	COG2188	Transcriptional regulator
IM697_RS23260	COG1126	abc transporter atp-binding protein
IM697_RS23265	COG0765	amino acid transport
IM697_RS23280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS23285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_RS23300	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS23325	COG1136	(ABC) transporter
IM697_RS23335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM697_RS23345	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IM697_RS23355	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS23365	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IM697_RS23395	COG2368	4-hydroxyphenylacetate
IM697_RS23400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_RS23405	COG1024	Enoyl-CoA hydratase
IM697_RS23410	COG1960	acyl-CoA dehydrogenase activity
IM697_RS23415	COG1024	Enoyl-CoA hydratase
IM697_RS23425	COG2172	sigma factor antagonist activity
IM697_RS23425	COG2208	phosphoserine phosphatase activity
IM697_RS23425	COG1366	Belongs to the anti-sigma-factor antagonist family
IM697_RS23445	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS23450	COG1024	Enoyl-CoA hydratase
IM697_RS23455	COG3321	synthase
IM697_RS23455	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS23455	COG0604	alcohol dehydrogenase
IM697_RS23470	COG2130	NADP-dependent
IM697_RS23475	COG0583	DNA-binding transcription factor activity
IM697_RS23490	COG2319	Wd-40 repeat
IM697_RS23490	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_RS23510	COG3345	alpha-galactosidase
IM697_RS23525	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IM697_RS23545	COG0477	Major facilitator Superfamily
IM697_RS23565	COG0583	DNA-binding transcription factor activity
IM697_RS23580	COG3290	protein histidine kinase activity
IM697_RS23585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_RS23590	COG4565	transcriptional regulatory protein
IM697_RS23655	COG2801	Transposase and inactivated derivatives
IM697_RS23665	COG0730	response to heat
IM697_RS23675	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS23680	COG0667	Aldo Keto reductase
IM697_RS23815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IM697_RS23980	COG1454	alcohol dehydrogenase
IM697_RS23980	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS24065	COG0539	negative regulation of cytoplasmic translation
IM697_RS24075	COG1397	ADP-ribosylglycohydrolase
IM697_RS24090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_RS24160	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS24200	COG2124	cytochrome p450
IM697_RS24210	COG2197	response regulator
IM697_RS24225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM697_RS24260	COG1169	isochorismate synthase
IM697_RS24265	COG1021	2,3-dihydroxybenzoate-AMP ligase
IM697_RS24270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_RS24270	COG3433	isochorismatase activity
IM697_RS24270	COG2226	methyltransferase
IM697_RS24275	COG3433	isochorismatase activity
IM697_RS24275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_RS24275	COG2226	methyltransferase
IM697_RS24310	COG1132	(ABC) transporter
IM697_RS24310	COG2375	cellular response to nickel ion
IM697_RS24320	COG0477	Major facilitator Superfamily
IM697_RS24330	COG4172	Belongs to the ABC transporter superfamily
IM697_RS24380	COG4977	sequence-specific DNA binding
IM697_RS24465	COG1309	transcriptional regulator
IM697_RS24495	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS24500	COG2130	NADP-dependent
IM697_RS24610	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
IM697_RS24620	COG0488	(ABC) transporter
IM697_RS24645	COG1032	radical SAM domain protein
IM697_RS24715	COG3387	PFAM Glycoside hydrolase 15-related
IM697_RS24745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM697_RS24745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM697_RS24760	COG0725	ABC transporter, periplasmic molybdate-binding protein
IM697_RS24795	COG0235	Class ii aldolase
IM697_RS24810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IM697_RS24840	COG0277	FAD linked oxidase domain protein
IM697_RS24860	COG1609	Transcriptional regulator
IM697_RS24875	COG0596	Alpha beta hydrolase
IM697_RS24900	COG0659	secondary active sulfate transmembrane transporter activity
IM697_RS24905	COG0789	Transcriptional regulator
IM697_RS24975	COG1278	Cold shock
IM697_RS24980	COG0513	Belongs to the DEAD box helicase family
IM697_RS25025	COG2267	carboxylic ester hydrolase activity
IM697_RS25035	COG3320	Male sterility
IM697_RS25035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_RS25040	COG0604	alcohol dehydrogenase
IM697_RS25040	COG3321	synthase
IM697_RS25045	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS25070	COG3845	ABC transporter
IM697_RS25080	COG2124	cytochrome p450
IM697_RS25090	COG0009	L-threonylcarbamoyladenylate synthase
IM697_RS25115	COG1045	serine acetyltransferase
IM697_RS25160	COG1846	Transcriptional regulator
IM697_RS25165	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IM697_RS25175	COG1918	ferrous iron import across plasma membrane
IM697_RS25175	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IM697_RS25185	COG3559	Exporter of polyketide antibiotics
IM697_RS25190	COG1131	(ABC) transporter
IM697_RS25205	COG1595	DNA-templated transcription, initiation
IM697_RS25210	COG2814	Major facilitator Superfamily
IM697_RS25220	COG0596	Alpha beta hydrolase
IM697_RS25245	COG3903	Transcriptional regulator
IM697_RS25245	COG3629	intracellular signal transduction
IM697_RS25280	COG3903	Transcriptional regulator
IM697_RS25280	COG3629	intracellular signal transduction
IM697_RS25295	COG0596	Alpha beta hydrolase
IM697_RS25305	COG1621	beta-fructofuranosidase activity
IM697_RS25315	COG1175	transmembrane transport
IM697_RS25320	COG0395	ABC-type sugar transport system, permease component
IM697_RS25330	COG1609	Transcriptional regulator
IM697_RS25335	COG0656	L-ascorbic acid biosynthetic process
IM697_RS25345	COG3547	Transposase (IS116 IS110 IS902 family)
IM697_RS25365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM697_RS25425	COG2207	Transcriptional regulator
IM697_RS25430	COG2223	nitrite transmembrane transporter activity
IM697_RS25440	COG2197	response regulator
IM697_RS25465	COG2814	Major facilitator Superfamily
IM697_RS25470	COG0181	hydroxymethylbilane synthase activity
IM697_RS25510	COG0366	Alpha amylase catalytic
IM697_RS25520	COG3281	Trehalose synthase
IM697_RS25525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM697_RS25590	COG5002	protein histidine kinase activity
IM697_RS25630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_RS25665	COG1672	PFAM Archaeal ATPase
IM697_RS25665	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IM697_RS25680	COG3345	alpha-galactosidase
IM697_RS25685	COG1940	carbohydrate kinase activity
IM697_RS25685	COG1846	Transcriptional regulator
IM697_RS25695	COG2340	Cysteine-rich secretory protein family
IM697_RS25710	COG0142	geranyltranstransferase activity
IM697_RS25720	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM697_RS25720	COG0515	serine threonine protein kinase
IM697_RS25730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS25745	COG0667	Aldo Keto reductase
IM697_RS25765	COG2304	oxidoreductase activity
IM697_RS25770	COG0328	RNA-DNA hybrid ribonuclease activity
IM697_RS25785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM697_RS25795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM697_RS25810	COG0596	Alpha beta hydrolase
IM697_RS25815	COG0740	serine-type endopeptidase activity
IM697_RS25820	COG0740	serine-type endopeptidase activity
IM697_RS25825	COG1396	sequence-specific DNA binding
IM697_RS25845	COG0515	serine threonine protein kinase
IM697_RS25845	COG2815	serine threonine protein kinase
IM697_RS25855	COG1716	ATPase activity
IM697_RS25855	COG1131	(ABC) transporter
IM697_RS25855	COG0842	Transport permease protein
IM697_RS25875	COG0667	Aldo Keto reductase
IM697_RS25880	COG0583	DNA-binding transcription factor activity
IM697_RS25890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_RS25895	COG0346	lactoylglutathione lyase activity
IM697_RS25910	COG0667	Aldo Keto reductase
IM697_RS25920	COG4941	Belongs to the sigma-70 factor family
IM697_RS25935	COG0640	Transcriptional regulator
IM697_RS26040	COG0589	response to stress
IM697_RS26065	COG1024	Enoyl-CoA hydratase
IM697_RS26100	COG1840	ABC-type Fe3 transport system, periplasmic component
IM697_RS26105	COG1178	ABC-type Fe3 transport system permease component
IM697_RS26110	COG3842	ATPase activity
IM697_RS26125	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS26130	COG2366	antibiotic biosynthetic process
IM697_RS26135	COG2124	cytochrome p450
IM697_RS26155	COG2070	2-Nitropropane dioxygenase
IM697_RS26160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_RS26180	COG0515	serine threonine protein kinase
IM697_RS26190	COG1960	acyl-CoA dehydrogenase activity
IM697_RS26210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM697_RS26220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM697_RS26230	COG2326	polyphosphate kinase activity
IM697_RS26245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_RS26250	COG5006	permease, DMT superfamily
IM697_RS26260	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_RS26260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM697_RS26280	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IM697_RS26300	COG0543	2 iron, 2 sulfur cluster binding
IM697_RS26315	COG0517	IMP dehydrogenase activity
IM697_RS26315	COG0516	GMP reductase activity
IM697_RS26325	COG0309	Hydrogenase expression formation protein (HypE)
IM697_RS26345	COG0516	GMP reductase activity
IM697_RS26345	COG0517	IMP dehydrogenase activity
IM697_RS26350	COG0045	succinate-CoA ligase (ADP-forming) activity
IM697_RS26350	COG1042	CoA-binding domain protein
IM697_RS26350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_RS26355	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IM697_RS26360	COG0589	response to stress
IM697_RS26380	COG0549	Belongs to the carbamate kinase family
IM697_RS26405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM697_RS26475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IM697_RS26480	COG0674	pyruvate-flavodoxin oxidoreductase activity
IM697_RS26485	COG1013	pyruvate-flavodoxin oxidoreductase activity
IM697_RS26490	COG0493	'glutamate synthase
IM697_RS26500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM697_RS26520	COG1063	alcohol dehydrogenase
IM697_RS26550	COG0205	6-phosphofructokinase activity
IM697_RS26565	COG2376	Dihydroxyacetone kinase
IM697_RS26570	COG1461	Dihydroxyacetone kinase
IM697_RS26585	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS26610	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM697_RS26610	COG1902	pentaerythritol trinitrate reductase activity
IM697_RS26615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_RS26640	COG2890	protein-(glutamine-N5) methyltransferase activity
IM697_RS26645	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IM697_RS26660	COG3458	cephalosporin-C deacetylase activity
IM697_RS26665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_RS26670	COG2188	Transcriptional regulator
IM697_RS26675	COG2226	methyltransferase
IM697_RS26680	COG1695	Transcriptional regulator
IM697_RS26690	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IM697_RS26705	COG2066	Belongs to the glutaminase family
IM697_RS26720	COG1113	amino acid transport
IM697_RS26725	COG2186	Transcriptional regulator
IM697_RS26730	COG1968	undecaprenyl-diphosphatase activity
IM697_RS26735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IM697_RS26740	COG1993	acr, cog1993
IM697_RS26745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IM697_RS26790	COG1175	transmembrane transport
IM697_RS26795	COG0395	ABC-type sugar transport system, permease component
IM697_RS26825	COG1960	acyl-CoA dehydrogenase activity
IM697_RS26830	COG3340	Belongs to the peptidase S51 family
IM697_RS26865	COG3291	Pkd domain containing protein
IM697_RS26870	COG0583	DNA-binding transcription factor activity
IM697_RS26885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_RS26890	COG0583	DNA-binding transcription factor activity
IM697_RS26895	COG2851	Citrate transporter
IM697_RS26905	COG0028	Belongs to the TPP enzyme family
IM697_RS26910	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IM697_RS26925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM697_RS26930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS26935	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS26950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IM697_RS26970	COG2340	Cysteine-rich secretory protein family
IM697_RS26975	COG0477	Major facilitator Superfamily
IM697_RS26995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM697_RS27000	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM697_RS27025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_RS27145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM697_RS27165	COG2132	Multicopper oxidase
IM697_RS27190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM697_RS27220	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS27225	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_RS27235	COG1129	ABC transporter
IM697_RS27240	COG1879	ABC-type sugar transport system periplasmic component
IM697_RS27260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_RS27300	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS27345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM697_RS27350	COG0297	glycogen (starch) synthase activity
IM697_RS27370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IM697_RS27390	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IM697_RS27405	COG0475	glutathione-regulated potassium exporter activity
IM697_RS27420	COG0492	ferredoxin-NADP+ reductase activity
IM697_RS27440	COG1129	ABC transporter
IM697_RS27445	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_RS27460	COG1132	(ABC) transporter
IM697_RS27470	COG1024	Enoyl-CoA hydratase
IM697_RS27475	COG0668	transmembrane transport
IM697_RS27485	COG2838	Isocitrate dehydrogenase
IM697_RS27530	COG1846	Transcriptional regulator
IM697_RS27535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IM697_RS27540	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS27555	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_RS27570	COG4689	acetoacetate decarboxylase
IM697_RS27585	COG0174	glutamine synthetase
IM697_RS27615	COG1116	anion transmembrane transporter activity
IM697_RS27620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_RS27625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM697_RS27630	COG1414	Transcriptional regulator
IM697_RS27695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_RS27705	COG1609	Transcriptional regulator
IM697_RS27710	COG0673	inositol 2-dehydrogenase activity
IM697_RS27715	COG0673	inositol 2-dehydrogenase activity
IM697_RS27720	COG0673	inositol 2-dehydrogenase activity
IM697_RS27735	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS27740	COG0673	inositol 2-dehydrogenase activity
IM697_RS27745	COG0673	inositol 2-dehydrogenase activity
IM697_RS27750	COG0673	inositol 2-dehydrogenase activity
IM697_RS27775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS27785	COG3718	enzyme involved in inositol metabolism
IM697_RS27790	COG3962	Belongs to the TPP enzyme family
IM697_RS27800	COG2188	Transcriptional regulator
IM697_RS27815	COG0494	nUDIX hydrolase
IM697_RS27835	COG0022	dehydrogenase e1 component
IM697_RS27840	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS27850	COG2208	phosphoserine phosphatase activity
IM697_RS27850	COG2770	Histidine kinase
IM697_RS27910	COG2267	carboxylic ester hydrolase activity
IM697_RS27945	COG0402	S-adenosylhomocysteine deaminase activity
IM697_RS27950	COG0022	dehydrogenase e1 component
IM697_RS27955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IM697_RS27960	COG0006	proline dipeptidase activity
IM697_RS27980	COG1136	(ABC) transporter
IM697_RS27990	COG2197	response regulator
IM697_RS28015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_RS28055	COG0515	serine threonine protein kinase
IM697_RS28055	COG2815	serine threonine protein kinase
IM697_RS28065	COG0515	serine threonine protein kinase
IM697_RS28085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IM697_RS28105	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS28185	COG2824	Alkylphosphonate utilization operon protein PhnA
IM697_RS28205	COG0659	secondary active sulfate transmembrane transporter activity
IM697_RS28215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM697_RS28250	COG2132	Multicopper oxidase
IM697_RS28255	COG0535	radical SAM domain protein
IM697_RS28265	COG1140	nitrate reductase beta subunit
IM697_RS28270	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IM697_RS28280	COG1017	nitric oxide dioxygenase activity
IM697_RS28280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM697_RS28290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM697_RS28305	COG2197	response regulator
IM697_RS28310	COG4585	Histidine kinase
IM697_RS28335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_RS28350	COG0583	DNA-binding transcription factor activity
IM697_RS28355	COG0156	8-amino-7-oxononanoate synthase activity
IM697_RS28360	COG1063	alcohol dehydrogenase
IM697_RS28410	COG2755	lipolytic protein G-D-S-L family
IM697_RS28425	COG2365	Tyrosine phosphatase family
IM697_RS28445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM697_RS28450	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM697_RS28465	COG1657	PFAM Prenyltransferase squalene oxidase
IM697_RS28475	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IM697_RS28485	COG1562	ergosterol biosynthetic process
IM697_RS28490	COG1134	teichoic acid transport
IM697_RS28535	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IM697_RS28540	COG2801	Transposase and inactivated derivatives
IM697_RS28540	COG3415	Transposase
IM697_RS28550	COG1024	Enoyl-CoA hydratase
IM697_RS28570	COG2183	response to ionizing radiation
IM697_RS28580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_RS28585	COG0488	(ABC) transporter
IM697_RS28595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM697_RS28605	COG2936	dipeptidyl-peptidase activity
IM697_RS28615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS28620	COG1113	amino acid transport
IM697_RS28630	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_RS28630	COG1024	Enoyl-CoA hydratase
IM697_RS28635	COG0183	Belongs to the thiolase family
IM697_RS28640	COG1960	acyl-CoA dehydrogenase activity
IM697_RS28645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_RS28655	COG3268	Saccharopine dehydrogenase
IM697_RS28690	COG0488	(ABC) transporter
IM697_RS28700	COG1834	amidinotransferase
IM697_RS28745	COG1793	dna ligase
IM697_RS28775	COG0183	Belongs to the thiolase family
IM697_RS28780	COG3485	protocatechuate 3,4-dioxygenase
IM697_RS28785	COG3485	protocatechuate 3,4-dioxygenase
IM697_RS28790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM697_RS28795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_RS28805	COG1672	PFAM Archaeal ATPase
IM697_RS28805	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IM697_RS28815	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IM697_RS28840	COG3511	phospholipase C
IM697_RS28850	COG1082	Xylose isomerase domain protein TIM barrel
IM697_RS28865	COG1129	ABC transporter
IM697_RS28875	COG2197	response regulator
IM697_RS28895	COG1136	(ABC) transporter
IM697_RS28905	COG3328	transposase activity
IM697_RS28920	COG3693	PFAM glycoside hydrolase, family 10
IM697_RS28940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_RS28945	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_RS28955	COG1414	Transcriptional regulator
IM697_RS29085	COG1414	Transcriptional regulator
IM697_RS29095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_RS29100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_RS29105	COG1116	anion transmembrane transporter activity
IM697_RS29115	COG1802	Transcriptional regulator
IM697_RS29120	COG3938	Belongs to the proline racemase family
IM697_RS29125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_RS29140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS29170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM697_RS29180	COG3469	chitinase activity
IM697_RS29195	COG1486	melibiose metabolic process
IM697_RS29205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS29215	COG1175	transmembrane transport
IM697_RS29225	COG3250	beta-galactosidase activity
IM697_RS29230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM697_RS29265	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS29280	COG4585	Histidine kinase
IM697_RS29285	COG2197	response regulator
IM697_RS29290	COG2409	Drug exporters of the RND superfamily
IM697_RS29320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IM697_RS29335	COG0166	Belongs to the GPI family
IM697_RS29340	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IM697_RS29345	COG0406	alpha-ribazole phosphatase activity
IM697_RS29355	COG1082	Xylose isomerase domain protein TIM barrel
IM697_RS29355	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IM697_RS29360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM697_RS29370	COG0477	Major facilitator Superfamily
IM697_RS29385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM697_RS29395	COG0438	transferase activity, transferring glycosyl groups
IM697_RS29415	COG3415	Transposase
IM697_RS29415	COG2801	Transposase and inactivated derivatives
IM697_RS29420	COG3467	pyridoxamine 5'-phosphate
IM697_RS29430	COG0477	Major facilitator Superfamily
IM697_RS29445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_RS29460	COG0438	transferase activity, transferring glycosyl groups
IM697_RS29490	COG0747	negative chemotaxis
IM697_RS29510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM697_RS29535	COG3433	isochorismatase activity
IM697_RS29535	COG1535	isochorismatase
IM697_RS29540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM697_RS29560	COG2382	esterase
IM697_RS29565	COG1132	(ABC) transporter
IM697_RS29575	COG1132	(ABC) transporter
IM697_RS29585	COG1120	ATPase activity
IM697_RS29590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS29595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS29600	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IM697_RS29615	COG0300	oxidoreductase activity
IM697_RS29615	COG3321	synthase
IM697_RS29615	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS29615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_RS29615	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS29625	COG1131	(ABC) transporter
IM697_RS29655	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS29665	COG0045	succinate-CoA ligase (ADP-forming) activity
IM697_RS29675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_RS29685	COG2223	nitrite transmembrane transporter activity
IM697_RS29750	COG0673	inositol 2-dehydrogenase activity
IM697_RS29760	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_RS29765	COG1129	ABC transporter
IM697_RS29770	COG1940	carbohydrate kinase activity
IM697_RS29780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_RS29790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM697_RS29795	COG3383	formate dehydrogenase (NAD+) activity
IM697_RS29810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM697_RS29815	COG1335	isochorismatase
IM697_RS29845	COG0656	L-ascorbic acid biosynthetic process
IM697_RS29855	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IM697_RS29865	COG5297	Belongs to the glycosyl hydrolase family 6
IM697_RS29870	COG4733	cellulase activity
IM697_RS29870	COG5297	Belongs to the glycosyl hydrolase family 6
IM697_RS29880	COG3401	FG-GAP repeat protein
IM697_RS29885	COG4106	trans-aconitate 2-methyltransferase activity
IM697_RS29885	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IM697_RS29890	COG2154	pterin-4-alpha-carbinolamine dehydratase
IM697_RS29920	COG1140	nitrate reductase beta subunit
IM697_RS29935	COG0443	Heat shock 70 kDa protein
IM697_RS29995	COG0028	Belongs to the TPP enzyme family
IM697_RS30005	COG0517	IMP dehydrogenase activity
IM697_RS30005	COG0516	GMP reductase activity
IM697_RS30010	COG0693	protein deglycase activity
IM697_RS30030	COG0488	(ABC) transporter
IM697_RS30035	COG0406	alpha-ribazole phosphatase activity
IM697_RS30040	COG1597	lipid kinase activity
IM697_RS30045	COG2226	methyltransferase
IM697_RS30105	COG3285	dna ligase
IM697_RS30105	COG1793	dna ligase
IM697_RS30120	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_RS30130	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS30160	COG1619	proteins homologs of microcin C7 resistance protein MccF
IM697_RS30170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_RS30175	COG2362	D-Aminopeptidase
IM697_RS30180	COG0310	cobalt ion transport
IM697_RS30185	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IM697_RS30195	COG1122	ATPase activity
IM697_RS30225	COG2226	methyltransferase
IM697_RS30230	COG2172	sigma factor antagonist activity
IM697_RS30230	COG1366	Belongs to the anti-sigma-factor antagonist family
IM697_RS30230	COG2208	phosphoserine phosphatase activity
IM697_RS30250	COG0596	Alpha beta hydrolase
IM697_RS30265	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_RS30280	COG0604	alcohol dehydrogenase
IM697_RS30285	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_RS30285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_RS30300	COG1960	acyl-CoA dehydrogenase activity
IM697_RS30305	COG0688	phosphatidylethanolamine metabolic process
IM697_RS30330	COG0559	Belongs to the binding-protein-dependent transport system permease family
IM697_RS30335	COG0559	Belongs to the binding-protein-dependent transport system permease family
IM697_RS30355	COG1929	Belongs to the glycerate kinase type-1 family
IM697_RS30375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IM697_RS30395	COG0640	Transcriptional regulator
IM697_RS30435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_RS30490	COG3940	Belongs to the glycosyl hydrolase 43 family
IM697_RS30545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM697_RS30550	COG1120	ATPase activity
IM697_RS30555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_RS30580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS30580	COG0723	plastoquinol--plastocyanin reductase activity
IM697_RS30590	COG0667	Aldo Keto reductase
IM697_RS30595	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS30600	COG3608	succinylglutamate desuccinylase aspartoacylase
IM697_RS30605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM697_RS30620	COG3842	ATPase activity
IM697_RS30635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS30640	COG1414	Transcriptional regulator
IM697_RS30645	COG1414	Transcriptional regulator
IM697_RS30660	COG0277	FAD linked oxidase domain protein
IM697_RS30660	COG0247	lactate metabolic process
IM697_RS30665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM697_RS30675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS30690	COG0251	oxidation-reduction process
IM697_RS30700	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS30710	COG3842	ATPase activity
IM697_RS30730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS30730	COG0723	plastoquinol--plastocyanin reductase activity
IM697_RS30740	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS30745	COG0477	Major facilitator Superfamily
IM697_RS30770	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS30780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_RS30790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_RS30795	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS30810	COG0477	Major facilitator Superfamily
IM697_RS30870	COG0483	inositol monophosphate 1-phosphatase activity
IM697_RS30880	COG1309	transcriptional regulator
IM697_RS30885	COG1131	(ABC) transporter
IM697_RS30915	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_RS30915	COG3848	Pyruvate phosphate dikinase
IM697_RS30920	COG0500	methyltransferase
IM697_RS30930	COG3321	synthase
IM697_RS30930	COG0604	alcohol dehydrogenase
IM697_RS30935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_RS30940	COG0156	8-amino-7-oxononanoate synthase activity
IM697_RS30945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_RS30950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_RS30955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_RS30960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_RS30965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_RS30970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IM697_RS31000	COG1960	acyl-CoA dehydrogenase activity
IM697_RS31010	COG3629	intracellular signal transduction
IM697_RS31035	COG2208	phosphoserine phosphatase activity
IM697_RS31060	COG1120	ATPase activity
IM697_RS31065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_RS31080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM697_RS31085	COG2226	methyltransferase
IM697_RS31090	COG1024	Enoyl-CoA hydratase
IM697_RS31110	COG2197	response regulator
IM697_RS31130	COG1953	Uracil, thiamine, allantoin
IM697_RS31140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM697_RS31180	COG0542	response to heat
IM697_RS31185	COG0405	Gamma-glutamyltransferase
IM697_RS31220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_RS31235	COG3328	transposase activity
IM697_RS31250	COG3415	Transposase
IM697_RS31250	COG2801	Transposase and inactivated derivatives
IM697_RS31300	COG3321	synthase
IM697_RS31300	COG0604	alcohol dehydrogenase
IM697_RS31315	COG2267	carboxylic ester hydrolase activity
IM697_RS31325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM697_RS31370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM697_RS31380	COG1940	carbohydrate kinase activity
IM697_RS31385	COG2188	Transcriptional regulator
IM697_RS31390	COG0673	inositol 2-dehydrogenase activity
IM697_RS31400	COG2197	response regulator
IM697_RS31430	COG1104	cysteine desulfurase activity
IM697_RS31445	COG2814	Major facilitator Superfamily
IM697_RS31505	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IM697_RS31510	COG1802	Transcriptional regulator
IM697_RS31520	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS31525	COG4266	Belongs to the allantoicase family
IM697_RS31530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM697_RS31535	COG1414	Transcriptional regulator
IM697_RS31550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IM697_RS31570	COG4264	IucA IucC family
IM697_RS31575	COG2304	oxidoreductase activity
IM697_RS31585	COG1733	regulation of RNA biosynthetic process
IM697_RS31590	COG0436	Aminotransferase
IM697_RS31600	COG0406	alpha-ribazole phosphatase activity
IM697_RS31615	COG2233	PERMEase
IM697_RS31630	COG2351	hydroxyisourate hydrolase activity
IM697_RS31665	COG3622	Belongs to the hyi family
IM697_RS31670	COG2084	Dehydrogenase
IM697_RS31675	COG0753	catalase activity
IM697_RS31680	COG3960	tartronate-semialdehyde synthase activity
IM697_RS31700	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS31705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM697_RS31710	COG2197	response regulator
IM697_RS31725	COG1280	lysine exporter protein (LysE YggA)
IM697_RS31735	COG0598	Magnesium transport protein CorA
IM697_RS31755	COG0589	response to stress
IM697_RS31760	COG2814	Major facilitator Superfamily
IM697_RS31765	COG0673	inositol 2-dehydrogenase activity
IM697_RS31770	COG1609	Transcriptional regulator
IM697_RS31775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_RS31790	COG3962	Belongs to the TPP enzyme family
IM697_RS31800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_RS31810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_RS31815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_RS31830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM697_RS31835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_RS31840	COG1937	Protein conserved in bacteria
IM697_RS31845	COG0730	response to heat
IM697_RS31850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_RS31855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_RS31855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_RS31900	COG2197	response regulator
IM697_RS31935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_RS31950	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_RS31975	COG0583	DNA-binding transcription factor activity
IM697_RS32015	COG3940	Belongs to the glycosyl hydrolase 43 family
IM697_RS32025	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IM697_RS32025	COG3608	succinylglutamate desuccinylase aspartoacylase
IM697_RS32030	COG2252	PERMEase
IM697_RS32035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IM697_RS32050	COG3835	regulator
IM697_RS32060	COG1802	Transcriptional regulator
IM697_RS32115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IM697_RS32125	COG1162	GTPase activity
IM697_RS32150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM697_RS32155	COG0277	FAD linked oxidase domain protein
IM697_RS32170	COG1175	transmembrane transport
IM697_RS32175	COG0395	ABC-type sugar transport system, permease component
IM697_RS32185	COG1131	(ABC) transporter
IM697_RS32230	COG4585	Histidine kinase
IM697_RS32235	COG2197	response regulator
IM697_RS32280	COG2040	homocysteine
IM697_RS32285	COG1609	Transcriptional regulator
IM697_RS32310	COG0395	ABC-type sugar transport system, permease component
IM697_RS32315	COG1175	transmembrane transport
IM697_RS32330	COG1609	Transcriptional regulator
IM697_RS32340	COG1175	transmembrane transport
IM697_RS32345	COG0395	ABC-type sugar transport system, permease component
IM697_RS32395	COG4977	sequence-specific DNA binding
IM697_RS32395	COG1917	Cupin 2, conserved barrel domain protein
IM697_RS32410	COG1960	acyl-CoA dehydrogenase activity
IM697_RS32435	COG0175	sulfate reduction
IM697_RS32440	COG0529	Catalyzes the synthesis of activated sulfate
IM697_RS32465	COG1116	anion transmembrane transporter activity
IM697_RS32470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_RS32485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM697_RS32510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM697_RS32525	COG1175	transmembrane transport
IM697_RS32535	COG0583	DNA-binding transcription factor activity
IM697_RS32620	COG1280	lysine exporter protein (LysE YggA)
IM697_RS32625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_RS32650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_RS32660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM697_RS32690	COG1404	Belongs to the peptidase S8 family
IM697_RS32755	COG2018	Roadblock/LC7 domain
IM697_RS32780	COG1174	glycine betaine transport
IM697_RS32790	COG2205	protein histidine kinase activity
IM697_RS32795	COG0745	RESPONSE REGULATOR receiver
IM697_RS32835	COG3284	Transcriptional regulator
IM697_RS32840	COG1073	alpha beta
IM697_RS32860	COG4821	SIS domain
IM697_RS32865	COG1737	Transcriptional regulator
IM697_RS32885	COG1175	transmembrane transport
IM697_RS32890	COG0395	ABC-type sugar transport system, permease component
IM697_RS32910	COG1472	Belongs to the glycosyl hydrolase 3 family
IM697_RS32925	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM697_RS32930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM697_RS32965	COG0330	HflC and HflK could
IM697_RS32995	COG4152	abc transporter atp-binding protein
IM697_RS33005	COG3220	belongs to the UPF0276 family
IM697_RS33025	COG3253	May function as heme-dependent peroxidase
IM697_RS33030	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IM697_RS33040	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM697_RS33065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IM697_RS33080	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IM697_RS33090	COG1175	transmembrane transport
IM697_RS33100	COG3250	beta-galactosidase activity
IM697_RS33105	COG1609	Transcriptional regulator
IM697_RS33110	COG0183	Belongs to the thiolase family
IM697_RS33115	COG1024	Enoyl-CoA hydratase
IM697_RS33115	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_RS33130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM697_RS33135	COG1316	TRANSCRIPTIONal
IM697_RS33160	COG0531	amino acid
IM697_RS33165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM697_RS33170	COG4214	carbohydrate transport
IM697_RS33180	COG4213	ABC transporter substrate-binding protein
IM697_RS33185	COG1940	carbohydrate kinase activity
IM697_RS33190	COG0395	ABC-type sugar transport system, permease component
IM697_RS33195	COG1175	transmembrane transport
IM697_RS33200	COG1653	transport
IM697_RS33225	COG1653	transport
IM697_RS33230	COG0395	ABC-type sugar transport system, permease component
IM697_RS33235	COG4209	transmembrane transport
IM697_RS33240	COG3458	cephalosporin-C deacetylase activity
IM697_RS33265	COG2205	protein histidine kinase activity
IM697_RS33270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IM697_RS33275	COG0137	argininosuccinate synthase activity
IM697_RS33280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM697_RS33290	COG2197	response regulator
IM697_RS33295	COG4585	Histidine kinase
IM697_RS33350	COG1024	Enoyl-CoA hydratase
IM697_RS33360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM697_RS33365	COG2235	arginine
IM697_RS33380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IM697_RS33415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM697_RS33420	COG1799	cell septum assembly
IM697_RS33425	COG0243	molybdopterin cofactor binding
IM697_RS33440	COG0277	FAD linked oxidase domain protein
IM697_RS33440	COG0247	lactate metabolic process
IM697_RS33455	COG4221	oxidoreductase activity
IM697_RS33475	COG1674	ftsk spoiiie
IM697_RS33490	COG0569	domain protein
IM697_RS33495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM697_RS33510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IM697_RS33515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IM697_RS33520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IM697_RS33535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IM697_RS33555	COG0367	asparagine synthase
IM697_RS33590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IM697_RS33605	COG4310	Domain of unknown function (DUF2172)
IM697_RS33615	COG1215	transferase activity, transferring glycosyl groups
IM697_RS33630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM697_RS33685	COG0477	Major facilitator Superfamily
IM697_RS33710	COG0583	DNA-binding transcription factor activity
IM697_RS33720	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS33730	COG0492	ferredoxin-NADP+ reductase activity
IM697_RS33735	COG3118	belongs to the thioredoxin family
IM697_RS33755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM697_RS33760	COG0531	amino acid
IM697_RS33765	COG0569	domain protein
IM697_RS33805	COG0756	dUTP diphosphatase activity
IM697_RS33830	COG2205	protein histidine kinase activity
IM697_RS33835	COG0745	RESPONSE REGULATOR receiver
IM697_RS33845	COG0483	inositol monophosphate 1-phosphatase activity
IM697_RS33850	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IM697_RS33895	COG0542	response to heat
IM697_RS33900	COG1435	thymidine kinase activity
IM697_RS33920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM697_RS33925	COG1802	Transcriptional regulator
IM697_RS33940	COG0612	Peptidase, M16
IM697_RS33945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IM697_RS33950	COG0523	cobalamin synthesis protein
IM697_RS33970	COG0372	Belongs to the citrate synthase family
IM697_RS33985	COG3290	protein histidine kinase activity
IM697_RS33990	COG4565	transcriptional regulatory protein
IM697_RS33995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_RS34005	COG0187	DNA topoisomerase II activity
IM697_RS34025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM697_RS34030	COG1802	Transcriptional regulator
IM697_RS34055	COG0514	ATP-dependent DNA helicase (RecQ)
IM697_RS34070	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IM697_RS34090	COG0588	phosphoglycerate mutase activity
IM697_RS34105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM697_RS34110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IM697_RS34115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IM697_RS34140	COG0531	amino acid
IM697_RS34145	COG4977	sequence-specific DNA binding
IM697_RS34160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM697_RS34170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM697_RS34175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM697_RS34185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IM697_RS34205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM697_RS34225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_RS34235	COG3321	synthase
IM697_RS34235	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS34235	COG0604	alcohol dehydrogenase
IM697_RS34245	COG2358	TRAP transporter, solute receptor (TAXI family
IM697_RS34250	COG2205	protein histidine kinase activity
IM697_RS34255	COG0745	RESPONSE REGULATOR receiver
IM697_RS34260	COG1126	abc transporter atp-binding protein
IM697_RS34265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_RS34270	COG0765	amino acid transport
IM697_RS34275	COG0765	amino acid transport
IM697_RS34300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IM697_RS34315	COG0628	permease
IM697_RS34340	COG1917	Cupin 2, conserved barrel domain protein
IM697_RS34340	COG2207	Transcriptional regulator
IM697_RS34345	COG1201	RNA secondary structure unwinding
IM697_RS34350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM697_RS34355	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS34365	COG1396	sequence-specific DNA binding
IM697_RS34370	COG1546	Belongs to the CinA family
IM697_RS34370	COG1058	Belongs to the CinA family
IM697_RS34380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM697_RS34390	COG1674	ftsk spoiiie
IM697_RS34400	COG4999	Histidine kinase
IM697_RS34400	COG2205	protein histidine kinase activity
IM697_RS34400	COG3850	Histidine kinase
IM697_RS34400	COG3437	response regulator, receiver
IM697_RS34405	COG2208	phosphoserine phosphatase activity
IM697_RS34405	COG2770	Histidine kinase
IM697_RS34435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IM697_RS34440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_RS34445	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IM697_RS34465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IM697_RS34470	COG0612	Peptidase, M16
IM697_RS34475	COG1185	polyribonucleotide nucleotidyltransferase activity
IM697_RS34480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IM697_RS34490	COG1674	ftsk spoiiie
IM697_RS34700	COG1404	Belongs to the peptidase S8 family
IM697_RS34715	COG1404	Belongs to the peptidase S8 family
IM697_RS34745	COG0455	bacterial-type flagellum organization
IM697_RS34760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IM697_RS34765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IM697_RS34775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IM697_RS34790	COG0779	Required for maturation of 30S ribosomal subunits
IM697_RS34810	COG0442	prolyl-tRNA aminoacylation
IM697_RS34825	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM697_RS34830	COG0750	zinc metalloprotease
IM697_RS34835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IM697_RS34880	COG0395	ABC-type sugar transport system, permease component
IM697_RS34885	COG4209	transmembrane transport
IM697_RS34890	COG1653	transport
IM697_RS34900	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS34935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_RS34940	COG1177	transmembrane transport
IM697_RS34945	COG1176	ABC-type spermidine putrescine transport system, permease component I
IM697_RS34950	COG3842	ATPase activity
IM697_RS34975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_RS34980	COG0584	glycerophosphoryl diester phosphodiesterase
IM697_RS35005	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS35015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM697_RS35020	COG1136	(ABC) transporter
IM697_RS35050	COG3842	ATPase activity
IM697_RS35055	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IM697_RS35065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM697_RS35095	COG0575	Belongs to the CDS family
IM697_RS35100	COG0233	cytoplasmic translational termination
IM697_RS35105	COG0528	UMP kinase activity
IM697_RS35115	COG0052	Belongs to the universal ribosomal protein uS2 family
IM697_RS35130	COG1191	sigma factor activity
IM697_RS35145	COG0792	nuclease activity
IM697_RS35165	COG0681	Belongs to the peptidase S26 family
IM697_RS35175	COG0681	Belongs to the peptidase S26 family
IM697_RS35180	COG0335	large ribosomal subunit rRNA binding
IM697_RS35185	COG0336	Belongs to the RNA methyltransferase TrmD family
IM697_RS35190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IM697_RS35195	COG1837	Belongs to the UPF0109 family
IM697_RS35200	COG0228	four-way junction DNA binding
IM697_RS35215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IM697_RS35225	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IM697_RS35260	COG0477	Major facilitator Superfamily
IM697_RS35265	COG1196	nuclear chromosome segregation
IM697_RS35275	COG1254	Belongs to the acylphosphatase family
IM697_RS35280	COG2340	Cysteine-rich secretory protein family
IM697_RS35285	COG1733	regulation of RNA biosynthetic process
IM697_RS35290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM697_RS35295	COG0571	ribonuclease III activity
IM697_RS35300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IM697_RS35315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IM697_RS35320	COG0742	ribosomal rna small subunit methyltransferase
IM697_RS35330	COG0326	Molecular chaperone. Has ATPase activity
IM697_RS35340	COG1461	Dihydroxyacetone kinase
IM697_RS35345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM697_RS35350	COG0351	phosphomethylpyrimidine kinase
IM697_RS35370	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM697_RS35375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IM697_RS35390	COG0776	regulation of translation
IM697_RS35400	COG0066	3-isopropylmalate dehydratase activity
IM697_RS35405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IM697_RS35410	COG1414	Transcriptional regulator
IM697_RS35460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM697_RS35465	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_RS35485	COG5002	protein histidine kinase activity
IM697_RS35490	COG2018	Roadblock/LC7 domain
IM697_RS35510	COG2018	Roadblock/LC7 domain
IM697_RS35535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_RS35540	COG5492	domain, Protein
IM697_RS35545	COG2353	YceI-like domain
IM697_RS35570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_RS35595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM697_RS35610	COG2957	Belongs to the agmatine deiminase family
IM697_RS35615	COG0804	urea catabolic process
IM697_RS35620	COG0832	Belongs to the urease beta subunit family
IM697_RS35620	COG0831	urea catabolic process
IM697_RS35630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM697_RS35635	COG0473	3-isopropylmalate dehydrogenase activity
IM697_RS35665	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS35670	COG0506	proline dehydrogenase activity
IM697_RS35675	COG3835	regulator
IM697_RS35680	COG0747	negative chemotaxis
IM697_RS35685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_RS35695	COG4608	Belongs to the ABC transporter superfamily
IM697_RS35710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IM697_RS35715	COG0440	acetolactate synthase activity
IM697_RS35725	COG5001	Diguanylate cyclase
IM697_RS35735	COG0667	Aldo Keto reductase
IM697_RS35740	COG2133	pyrroloquinoline quinone binding
IM697_RS35750	COG1672	PFAM Archaeal ATPase
IM697_RS35750	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IM697_RS35765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_RS35770	COG2409	Drug exporters of the RND superfamily
IM697_RS35785	COG2226	methyltransferase
IM697_RS35790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IM697_RS35800	COG0154	amidase activity
IM697_RS35805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IM697_RS35825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IM697_RS35835	COG4221	oxidoreductase activity
IM697_RS35850	COG0596	Alpha beta hydrolase
IM697_RS35855	COG0482	sulfurtransferase activity
IM697_RS35860	COG3023	N-Acetylmuramoyl-L-alanine amidase
IM697_RS35900	COG2860	membrane
IM697_RS35910	COG0444	Belongs to the ABC transporter superfamily
IM697_RS35920	COG4166	transmembrane transport
IM697_RS35925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_RS35945	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IM697_RS35950	COG0509	glycine decarboxylation via glycine cleavage system
IM697_RS35955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_RS35960	COG1760	l-serine dehydratase
IM697_RS35975	COG3409	Peptidoglycan-binding domain 1 protein
IM697_RS35975	COG3757	hydrolase, family 25
IM697_RS35985	COG0789	Transcriptional regulator
IM697_RS36010	COG1024	Enoyl-CoA hydratase
IM697_RS36015	COG1376	ErfK ybiS ycfS ynhG family protein
IM697_RS36030	COG2197	response regulator
IM697_RS36035	COG4585	Histidine kinase
IM697_RS36045	COG1131	(ABC) transporter
IM697_RS36055	COG1132	(ABC) transporter
IM697_RS36060	COG1132	(ABC) transporter
IM697_RS36065	COG1132	(ABC) transporter
IM697_RS36090	COG0058	SHG alpha-glucan phosphorylase activity
IM697_RS36100	COG0366	Alpha amylase catalytic
IM697_RS36105	COG0366	Alpha amylase catalytic
IM697_RS36115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM697_RS36125	COG0492	ferredoxin-NADP+ reductase activity
IM697_RS36125	COG3118	belongs to the thioredoxin family
IM697_RS36135	COG1522	sequence-specific DNA binding
IM697_RS36145	COG0667	Aldo Keto reductase
IM697_RS36150	COG1301	dicarboxylic acid transport
IM697_RS36155	COG3290	protein histidine kinase activity
IM697_RS36160	COG4565	transcriptional regulatory protein
IM697_RS36170	COG1653	transport
IM697_RS36175	COG1175	transmembrane transport
IM697_RS36180	COG0395	ABC-type sugar transport system, permease component
IM697_RS36195	COG0205	6-phosphofructokinase activity
IM697_RS36200	COG0280	phosphate acetyltransferase
IM697_RS36200	COG0857	belongs to the CobB CobQ family
IM697_RS36205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM697_RS36265	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_RS36265	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_RS36280	COG2329	Antibiotic biosynthesis monooxygenase
IM697_RS36285	COG2124	cytochrome p450
IM697_RS36295	COG2159	amidohydrolase
IM697_RS36365	COG2205	protein histidine kinase activity
IM697_RS36370	COG0745	RESPONSE REGULATOR receiver
IM697_RS36390	COG0183	Belongs to the thiolase family
IM697_RS36395	COG0346	lactoylglutathione lyase activity
IM697_RS36410	COG1131	(ABC) transporter
IM697_RS36435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS36445	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IM697_RS36460	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_RS36480	COG4585	Histidine kinase
IM697_RS36485	COG2197	response regulator
IM697_RS36500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM697_RS36505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IM697_RS36510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM697_RS36515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IM697_RS36520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM697_RS36525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IM697_RS36530	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM697_RS36550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM697_RS36555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_RS36560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM697_RS36570	COG2890	protein-(glutamine-N5) methyltransferase activity
IM697_RS36575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IM697_RS36580	COG0254	rRNA binding
IM697_RS36595	COG0083	homoserine kinase activity
IM697_RS36600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IM697_RS36605	COG0460	homoserine dehydrogenase
IM697_RS36610	COG0019	diaminopimelate decarboxylase activity
IM697_RS36615	COG0018	arginyl-trna synthetase
IM697_RS36615	COG0018	arginyl-trna synthetase
IM697_RS36635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS36655	COG0431	NADPH-dependent FMN reductase
IM697_RS36660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS36665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS36670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_RS36675	COG1126	abc transporter atp-binding protein
IM697_RS36680	COG0765	amino acid transport
IM697_RS36685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_RS36695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS36700	COG0765	amino acid transport
IM697_RS36705	COG0745	RESPONSE REGULATOR receiver
IM697_RS36725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_RS36730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS36735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IM697_RS36760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM697_RS36760	COG1116	anion transmembrane transporter activity
IM697_RS36765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_RS36820	COG0514	ATP-dependent DNA helicase (RecQ)
IM697_RS36910	COG3251	PFAM MbtH domain protein
IM697_RS36915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_RS36950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_RS36955	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IM697_RS36960	COG3285	dna ligase
IM697_RS36960	COG1793	dna ligase
IM697_RS36980	COG2205	protein histidine kinase activity
IM697_RS36990	COG0772	Belongs to the SEDS family
IM697_RS36995	COG0768	penicillin binding
IM697_RS37025	COG0791	NLP P60 protein
IM697_RS37070	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IM697_RS37085	COG0745	RESPONSE REGULATOR receiver
IM697_RS37090	COG2205	protein histidine kinase activity
IM697_RS37095	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM697_RS37095	COG0567	Dehydrogenase, E1 component
IM697_RS37105	COG3629	intracellular signal transduction
IM697_RS37105	COG3903	Transcriptional regulator
IM697_RS37145	COG0604	alcohol dehydrogenase
IM697_RS37150	COG0281	malic enzyme
IM697_RS37165	COG1126	abc transporter atp-binding protein
IM697_RS37190	COG0582	viral genome integration into host DNA
IM697_RS37255	COG1131	(ABC) transporter
IM697_RS37350	COG0142	geranyltranstransferase activity
IM697_RS37355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM697_RS37395	COG1597	lipid kinase activity
IM697_RS37410	COG1309	transcriptional regulator
IM697_RS37415	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS37420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM697_RS37425	COG0363	glucosamine-6-phosphate deaminase activity
IM697_RS37430	COG1472	Belongs to the glycosyl hydrolase 3 family
IM697_RS37435	COG0395	ABC-type sugar transport system, permease component
IM697_RS37440	COG1175	transmembrane transport
IM697_RS37445	COG2182	Extracellular solute-binding protein
IM697_RS37450	COG2188	Transcriptional regulator
IM697_RS37455	COG1966	Carbon starvation protein
IM697_RS37490	COG2124	cytochrome p450
IM697_RS37500	COG0242	peptide deformylase activity
IM697_RS37515	COG2199	diguanylate cyclase activity
IM697_RS37515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IM697_RS37520	COG5662	AntiSigma factor
IM697_RS37525	COG1595	DNA-templated transcription, initiation
IM697_RS37535	COG2135	peptidase activity
IM697_RS37555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_RS37560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_RS37565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_RS37590	COG2197	response regulator
IM697_RS37600	COG3321	synthase
IM697_RS37600	COG0604	alcohol dehydrogenase
IM697_RS37610	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_RS37630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_RS37635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM697_RS37640	COG2130	NADP-dependent
IM697_RS37645	COG1819	glycosyl
IM697_RS37675	COG0596	Alpha beta hydrolase
IM697_RS37685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IM697_RS37690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_RS37700	COG0596	Alpha beta hydrolase
IM697_RS37710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_RS37745	COG1960	acyl-CoA dehydrogenase activity
IM697_RS37780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IM697_RS37800	COG0483	inositol monophosphate 1-phosphatase activity
IM697_RS37845	COG1615	UPF0182 protein
IM697_RS37855	COG3480	Lon protease (S16) C-terminal proteolytic domain
IM697_RS37905	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM697_RS37940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_RS37945	COG0210	DNA helicase
IM697_RS37970	COG0596	Alpha beta hydrolase
IM697_RS38045	COG1432	Conserved Protein
IM697_RS38055	COG2095	MarC family integral membrane protein
IM697_RS38070	COG2814	Major facilitator Superfamily
IM697_RS38080	COG0598	Magnesium transport protein CorA
IM697_RS38115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM697_RS38120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_RS38130	COG1595	DNA-templated transcription, initiation
IM697_RS38150	COG1024	Enoyl-CoA hydratase
IM697_RS38155	COG0519	Catalyzes the synthesis of GMP from XMP
IM697_RS38165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IM697_RS38170	COG1611	Belongs to the LOG family
IM697_RS38175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_RS38210	COG2197	response regulator
IM697_RS38215	COG4585	Histidine kinase
IM697_RS38225	COG1131	(ABC) transporter
IM697_RS38240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_RS38255	COG4608	Belongs to the ABC transporter superfamily
IM697_RS38260	COG0444	Belongs to the ABC transporter superfamily
IM697_RS38265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_RS38270	COG0601	transmembrane transport
IM697_RS38280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_RS38285	COG0747	negative chemotaxis
IM697_RS38290	COG0601	transmembrane transport
IM697_RS38295	COG0444	Belongs to the ABC transporter superfamily
IM697_RS38300	COG4608	Belongs to the ABC transporter superfamily
IM697_RS38305	COG2197	response regulator
IM697_RS38310	COG4585	Histidine kinase
IM697_RS38315	COG2409	Drug exporters of the RND superfamily
IM697_RS38325	COG0346	lactoylglutathione lyase activity
IM697_RS38335	COG4608	Belongs to the ABC transporter superfamily
IM697_RS38340	COG0444	Belongs to the ABC transporter superfamily
IM697_RS38345	COG0601	transmembrane transport
IM697_RS38350	COG0747	negative chemotaxis
IM697_RS38355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_RS38360	COG1217	gtp-binding protein TYPA
IM697_RS38380	COG1053	succinate dehydrogenase
IM697_RS38430	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS38435	COG0583	DNA-binding transcription factor activity
IM697_RS38485	COG3119	arylsulfatase activity
IM697_RS38490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM697_RS38535	COG0012	GTP binding
IM697_RS38550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IM697_RS38555	COG1570	exodeoxyribonuclease VII activity
IM697_RS38560	COG1722	exodeoxyribonuclease VII activity
IM697_RS38565	COG0778	Nitroreductase
IM697_RS38590	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IM697_RS38590	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IM697_RS38595	COG0114	fumarate hydratase activity
IM697_RS38610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_RS38630	COG1136	(ABC) transporter
IM697_RS38645	COG0450	alkyl hydroperoxide reductase
IM697_RS38650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_RS38665	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IM697_RS38670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM697_RS38735	COG2197	response regulator
IM697_RS38770	COG2894	cell division
IM697_RS38845	COG1595	DNA-templated transcription, initiation
IM697_RS38890	COG2610	gluconate transmembrane transporter activity
IM697_RS38895	COG0251	oxidation-reduction process
IM697_RS38900	COG1414	Transcriptional regulator
IM697_RS38915	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IM697_RS38935	COG0436	Aminotransferase
IM697_RS38965	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IM697_RS38975	COG0477	Major facilitator Superfamily
IM697_RS38980	COG1309	transcriptional regulator
IM697_RS39010	COG1331	Highly conserved protein containing a thioredoxin domain
IM697_RS39025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_RS39035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM697_RS39050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IM697_RS39055	COG2255	four-way junction helicase activity
IM697_RS39060	COG1595	DNA-templated transcription, initiation
IM697_RS39080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM697_RS39095	COG1064	alcohol dehydrogenase
IM697_RS39105	COG1136	(ABC) transporter
IM697_RS39135	COG2986	histidine ammonia-lyase
IM697_RS39145	COG1024	Enoyl-CoA hydratase
IM697_RS39155	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IM697_RS39165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_RS39185	COG0424	maF-like protein
IM697_RS39195	COG4770	biotin carboxylase activity
IM697_RS39230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM697_RS39245	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS39265	COG0477	Major facilitator Superfamily
IM697_RS39275	COG1595	DNA-templated transcription, initiation
IM697_RS39280	COG0745	RESPONSE REGULATOR receiver
IM697_RS39285	COG2205	protein histidine kinase activity
IM697_RS39310	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_RS39325	COG0583	DNA-binding transcription factor activity
IM697_RS39330	COG0583	DNA-binding transcription factor activity
IM697_RS39335	COG2814	Major facilitator Superfamily
IM697_RS39370	COG1079	Belongs to the binding-protein-dependent transport system permease family
IM697_RS39380	COG3845	ABC transporter
IM697_RS39385	COG1744	ABC transporter substrate-binding protein PnrA-like
IM697_RS39390	COG1744	ABC transporter substrate-binding protein PnrA-like
IM697_RS39395	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IM697_RS39395	COG1473	amidohydrolase
IM697_RS39410	COG2226	methyltransferase
IM697_RS39425	COG2089	acid synthase
IM697_RS39440	COG1216	Glycosyl transferase, family 2
IM697_RS39460	COG1216	Glycosyl transferase, family 2
IM697_RS39480	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_RS39480	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_RS39495	COG1595	DNA-templated transcription, initiation
IM697_RS39585	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IM697_RS39595	COG2009	succinate dehydrogenase
IM697_RS39605	COG1053	succinate dehydrogenase
IM697_RS39650	COG2409	Drug exporters of the RND superfamily
IM697_RS39655	COG0745	RESPONSE REGULATOR receiver
IM697_RS39660	COG2205	protein histidine kinase activity
IM697_RS39675	COG1408	metallophosphoesterase
IM697_RS39685	COG1686	Belongs to the peptidase S11 family
IM697_RS39690	COG1295	ribonuclease BN
IM697_RS39710	COG0180	Tryptophanyl-tRNA synthetase
IM697_RS39715	COG1595	DNA-templated transcription, initiation
IM697_RS39735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_RS39740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM697_RS39755	COG0512	Glutamine amidotransferase of anthranilate synthase
IM697_RS39755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM697_RS39760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM697_RS39780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_RS39785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_RS39800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_RS39805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_RS39820	COG4176	ABC-type proline glycine betaine transport system permease component
IM697_RS39825	COG0517	IMP dehydrogenase activity
IM697_RS39825	COG4175	Glycine betaine
IM697_RS39835	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS39840	COG2318	DinB family
IM697_RS39920	COG0039	L-malate dehydrogenase activity
IM697_RS39940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM697_RS39955	COG0515	serine threonine protein kinase
IM697_RS39955	COG2815	serine threonine protein kinase
IM697_RS39965	COG0515	serine threonine protein kinase
IM697_RS39985	COG3409	Peptidoglycan-binding domain 1 protein
IM697_RS40015	COG2815	serine threonine protein kinase
IM697_RS40015	COG0515	serine threonine protein kinase
IM697_RS40025	COG0138	bifunctional purine biosynthesis protein purh
IM697_RS40055	COG0045	succinate-CoA ligase (ADP-forming) activity
IM697_RS40070	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IM697_RS40075	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IM697_RS40080	COG0714	Associated with various cellular activities
IM697_RS40095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_RS40095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_RS40130	COG0791	NLP P60 protein
IM697_RS40135	COG2197	response regulator
IM697_RS40180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IM697_RS40180	COG0519	Catalyzes the synthesis of GMP from XMP
IM697_RS40215	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS40225	COG0515	serine threonine protein kinase
IM697_RS40230	COG0515	serine threonine protein kinase
IM697_RS40235	COG2815	serine threonine protein kinase
IM697_RS40235	COG0515	serine threonine protein kinase
IM697_RS40240	COG2815	serine threonine protein kinase
IM697_RS40240	COG0515	serine threonine protein kinase
IM697_RS40245	COG2815	serine threonine protein kinase
IM697_RS40245	COG0515	serine threonine protein kinase
IM697_RS40255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM697_RS40265	COG0516	GMP reductase activity
IM697_RS40275	COG1595	DNA-templated transcription, initiation
IM697_RS40290	COG0583	DNA-binding transcription factor activity
IM697_RS40300	COG2132	Multicopper oxidase
IM697_RS40305	COG4221	oxidoreductase activity
IM697_RS40315	COG0459	protein refolding
IM697_RS40325	COG0726	polysaccharide deacetylase
IM697_RS40330	COG0726	polysaccharide deacetylase
IM697_RS40340	COG4941	Belongs to the sigma-70 factor family
IM697_RS40350	COG1316	TRANSCRIPTIONal
IM697_RS40355	COG1609	Transcriptional regulator
IM697_RS40360	COG1472	Belongs to the glycosyl hydrolase 3 family
IM697_RS40370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IM697_RS40395	COG0802	atpase or kinase
IM697_RS40405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM697_RS40415	COG0736	holo-[acyl-carrier-protein] synthase activity
IM697_RS40450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM697_RS40475	COG1072	(Pantothenic acid kinase))
IM697_RS40500	COG3321	synthase
IM697_RS40500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_RS40510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_RS40515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM697_RS40520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IM697_RS40525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IM697_RS40545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM697_RS40555	COG2843	Capsule synthesis protein
IM697_RS40565	COG0101	tRNA pseudouridine synthase activity
IM697_RS40570	COG0203	ribosomal protein L17
IM697_RS40575	COG0202	RNA polymerase activity
IM697_RS40580	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IM697_RS40585	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IM697_RS40590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IM697_RS40595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IM697_RS40605	COG0563	adenylate kinase activity
IM697_RS40615	COG0200	Binds to the 23S rRNA
IM697_RS40620	COG1841	ribosomal large subunit assembly
IM697_RS40625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IM697_RS40630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IM697_RS40635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IM697_RS40640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IM697_RS40645	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM697_RS40650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IM697_RS40655	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IM697_RS40660	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IM697_RS40665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IM697_RS40670	COG0255	Belongs to the universal ribosomal protein uL29 family
IM697_RS40675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IM697_RS40680	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IM697_RS40685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IM697_RS40690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IM697_RS40695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IM697_RS40700	COG0089	rRNA binding
IM697_RS40705	COG0088	Forms part of the polypeptide exit tunnel
IM697_RS40710	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IM697_RS40715	COG0051	transcription antitermination factor activity, RNA binding
IM697_RS40720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IM697_RS40750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM697_RS40760	COG0110	maltose O-acetyltransferase activity
IM697_RS40770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IM697_RS40780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IM697_RS40785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM697_RS40790	COG0049	tRNA binding
IM697_RS40795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IM697_RS40805	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IM697_RS40810	COG0085	RNA polymerase activity
IM697_RS40815	COG0222	ribosome binding
IM697_RS40820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IM697_RS40830	COG0081	regulation of translation
IM697_RS40845	COG0250	Participates in transcription elongation, termination and antitermination
IM697_RS40860	COG0436	Aminotransferase
IM697_RS40865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_RS40870	COG1309	transcriptional regulator
IM697_RS40880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IM697_RS40890	COG0477	Major facilitator Superfamily
IM697_RS40905	COG2030	dehydratase
IM697_RS40910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM697_RS40925	COG0402	S-adenosylhomocysteine deaminase activity
IM697_RS40930	COG0702	epimerase
IM697_RS40950	COG1666	GTP binding
IM697_RS40955	COG2261	transglycosylase associated protein
IM697_RS40970	COG3304	Inner membrane component domain
IM697_RS40975	COG0501	Belongs to the peptidase M48B family
IM697_RS40980	COG1007	ATP synthesis coupled electron transport
IM697_RS40990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM697_RS40995	COG0713	ATP synthesis coupled electron transport
IM697_RS41000	COG0839	Belongs to the complex I subunit 6 family
IM697_RS41005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS41010	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IM697_RS41015	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS41020	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS41025	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS41045	COG0674	pyruvate-flavodoxin oxidoreductase activity
IM697_RS41045	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IM697_RS41050	COG1013	pyruvate-flavodoxin oxidoreductase activity
IM697_RS41060	COG1733	regulation of RNA biosynthetic process
IM697_RS41065	COG0702	epimerase
IM697_RS41080	COG2234	aminopeptidase activity
IM697_RS41080	COG4935	Belongs to the peptidase S8 family
IM697_RS41095	COG0154	amidase activity
IM697_RS41110	COG1131	(ABC) transporter
IM697_RS41125	COG0142	geranyltranstransferase activity
IM697_RS41140	COG0561	phosphatase activity
IM697_RS41155	COG0514	ATP-dependent DNA helicase (RecQ)
IM697_RS41160	COG1007	ATP synthesis coupled electron transport
IM697_RS41170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM697_RS41175	COG0713	ATP synthesis coupled electron transport
IM697_RS41180	COG0839	Belongs to the complex I subunit 6 family
IM697_RS41185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS41190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IM697_RS41195	COG1034	ATP synthesis coupled electron transport
IM697_RS41200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IM697_RS41210	COG0649	NAD binding
IM697_RS41215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS41220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_RS41240	COG0242	peptide deformylase activity
IM697_RS41265	COG2226	methyltransferase
IM697_RS41295	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IM697_RS41310	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IM697_RS41315	COG1278	Cold shock
IM697_RS41320	COG1396	sequence-specific DNA binding
IM697_RS41350	COG1053	succinate dehydrogenase
IM697_RS41360	COG4213	ABC transporter substrate-binding protein
IM697_RS41375	COG0183	Belongs to the thiolase family
IM697_RS41390	COG1309	transcriptional regulator
IM697_RS41415	COG1573	uracil-dna glycosylase
IM697_RS41420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IM697_RS41430	COG0163	prenyltransferase activity
IM697_RS41450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IM697_RS41490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM697_RS41495	COG1333	cytochrome c biogenesis protein
IM697_RS41500	COG0785	Cytochrome C biogenesis protein
IM697_RS41505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM697_RS41515	COG0406	alpha-ribazole phosphatase activity
IM697_RS41520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM697_RS41530	COG0582	viral genome integration into host DNA
IM697_RS41600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IM697_RS41625	COG0697	spore germination
IM697_RS41630	COG0583	DNA-binding transcription factor activity
IM697_RS41645	COG2205	protein histidine kinase activity
IM697_RS41660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_RS41680	COG1742	UPF0060 membrane protein
IM697_RS41695	COG1690	Belongs to the RtcB family
IM697_RS41715	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IM697_RS41720	COG0018	arginyl-trna synthetase
IM697_RS41745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_RS41755	COG0113	porphobilinogen synthase activity
IM697_RS41765	COG1648	precorrin-2 dehydrogenase activity
IM697_RS41765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM697_RS41770	COG0181	hydroxymethylbilane synthase activity
IM697_RS41775	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IM697_RS41780	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IM697_RS41830	COG0123	including yeast histone deacetylase and acetoin utilization protein
IM697_RS41845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_RS41865	COG0180	Tryptophanyl-tRNA synthetase
IM697_RS41870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM697_RS41880	COG1129	ABC transporter
IM697_RS41880	COG0842	Transport permease protein
IM697_RS41895	COG4991	sh3 domain protein
IM697_RS41900	COG4991	sh3 domain protein
IM697_RS41910	COG0129	dihydroxy-acid dehydratase activity
IM697_RS41915	COG1309	transcriptional regulator
IM697_RS41920	COG1082	Xylose isomerase domain protein TIM barrel
IM697_RS41925	COG0248	Ppx GppA phosphatase
IM697_RS41945	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IM697_RS41965	COG1595	DNA-templated transcription, initiation
IM697_RS41975	COG0745	RESPONSE REGULATOR receiver
IM697_RS41980	COG2205	protein histidine kinase activity
IM697_RS42005	COG0739	heme binding
IM697_RS42045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IM697_RS42065	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IM697_RS42075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IM697_RS42080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IM697_RS42105	COG1660	Displays ATPase and GTPase activities
IM697_RS42125	COG0649	NAD binding
IM697_RS42165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM697_RS42180	COG0302	gtp cyclohydrolase
IM697_RS42195	COG0037	tRNA processing
IM697_RS42205	COG2027	D-alanyl-D-alanine carboxypeptidase
IM697_RS42210	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IM697_RS42220	COG0586	Pfam SNARE associated Golgi protein
IM697_RS42225	COG0393	Putative heavy-metal-binding
IM697_RS42230	COG0789	Transcriptional regulator
IM697_RS42240	COG0076	glutamate decarboxylase activity
IM697_RS42260	COG2318	DinB family
IM697_RS42275	COG1733	regulation of RNA biosynthetic process
IM697_RS42280	COG1012	belongs to the aldehyde dehydrogenase family
IM697_RS42300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IM697_RS42310	COG0254	rRNA binding
IM697_RS42315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM697_RS42320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM697_RS42325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM697_RS42350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM697_RS42350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM697_RS42385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_RS42420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM697_RS42445	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM697_RS42495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_RS42525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_RS42555	COG0367	asparagine synthase
IM697_RS42600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM697_RS42620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM697_RS42625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM697_RS42635	COG1280	lysine exporter protein (LysE YggA)
IM697_RS42645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM697_RS42650	COG2954	triphosphatase activity
IM697_RS42660	COG0477	Major facilitator Superfamily
IM697_RS42690	COG3251	PFAM MbtH domain protein
IM697_RS42695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IM697_RS42715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IM697_RS42720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM697_RS42720	COG1754	DNA topoisomerase type I activity
IM697_RS42740	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IM697_RS42745	COG2172	sigma factor antagonist activity
IM697_RS42750	COG1366	Belongs to the anti-sigma-factor antagonist family
IM697_RS42815	COG0659	secondary active sulfate transmembrane transporter activity
IM697_RS42820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM697_RS42825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM697_RS42835	COG2267	carboxylic ester hydrolase activity
IM697_RS42865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_RS42890	COG0003	Pfam Anion-transporting ATPase
IM697_RS42900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_RS42910	COG1408	metallophosphoesterase
IM697_RS42940	COG1609	Transcriptional regulator
IM697_RS43020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM697_RS43025	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM697_RS43035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM697_RS43050	COG0402	S-adenosylhomocysteine deaminase activity
IM697_RS43060	COG0667	Aldo Keto reductase
IM697_RS43075	COG2197	response regulator
IM697_RS43080	COG4585	Histidine kinase
IM697_RS43115	COG4585	Histidine kinase
IM697_RS43120	COG2197	response regulator
IM697_RS43125	COG2409	Drug exporters of the RND superfamily
IM697_RS43130	COG1408	metallophosphoesterase
IM697_RS43145	COG1063	alcohol dehydrogenase
IM697_RS43155	COG1309	transcriptional regulator
IM697_RS43170	COG3328	transposase activity
IM697_RS43180	COG2318	DinB family
IM697_RS43185	COG2226	methyltransferase
IM697_RS43245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM697_RS43285	COG1595	DNA-templated transcription, initiation
IM697_RS43290	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_RS43290	COG2319	Wd-40 repeat
IM697_RS43295	COG2188	Transcriptional regulator
IM697_RS43315	COG0701	Predicted permease
IM697_RS43335	COG1295	ribonuclease BN
IM697_RS43400	COG1595	DNA-templated transcription, initiation
IM697_RS43430	COG2205	protein histidine kinase activity
IM697_RS43460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IM697_RS43465	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IM697_RS43490	COG0693	protein deglycase activity
IM697_RS43500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM697_RS43510	COG0463	Glycosyl transferase, family 2
IM697_RS43560	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IM697_RS43575	COG1131	(ABC) transporter
IM697_RS43580	COG3559	Exporter of polyketide antibiotics
IM697_RS43585	COG2124	cytochrome p450
IM697_RS43610	COG2197	response regulator
IM697_RS43615	COG4585	Histidine kinase
IM697_RS43620	COG2197	response regulator
IM697_RS43625	COG4585	Histidine kinase
IM697_RS43650	COG3844	kynureninase activity
IM697_RS43665	COG0477	Major facilitator Superfamily
IM697_RS43670	COG0191	fructose-bisphosphate aldolase activity
IM697_RS43675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IM697_RS43695	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM697_RS43710	COG0542	response to heat
IM697_RS43750	COG1305	Transglutaminase-like
IM697_RS43755	COG4213	ABC transporter substrate-binding protein
IM697_RS43770	COG0789	Transcriptional regulator
IM697_RS43775	COG0484	heat shock protein binding
IM697_RS43780	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IM697_RS43785	COG0443	Heat shock 70 kDa protein
IM697_RS43790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM697_RS43795	COG2181	nitrate reductase activity
IM697_RS43795	COG0247	lactate metabolic process
IM697_RS43800	COG2826	transposase and inactivated derivatives, IS30 family
IM697_RS43880	COG0717	Belongs to the dCTP deaminase family
IM697_RS43890	COG1309	transcriptional regulator
IM697_RS43905	COG2124	cytochrome p450
IM697_RS43905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM697_RS43910	COG1231	oxidoreductase activity
IM697_RS43940	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
IM697_RS44000	COG0667	Aldo Keto reductase
IM697_RS44005	COG2080	2 iron, 2 sulfur cluster binding
IM697_RS44010	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IM697_RS44015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IM697_RS44020	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IM697_RS44020	COG3608	succinylglutamate desuccinylase aspartoacylase
IM697_RS44025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM697_RS44060	COG1278	Cold shock
IM697_RS44065	COG0513	Belongs to the DEAD box helicase family
IM697_RS44085	COG4585	Histidine kinase
IM697_RS44090	COG2197	response regulator
IM697_RS44105	COG1132	(ABC) transporter
IM697_RS44115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM697_RS44135	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_RS44135	COG2319	Wd-40 repeat
IM697_RS44145	COG3250	beta-galactosidase activity
IM697_RS44155	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_RS44195	COG3835	regulator
IM697_RS44210	COG2188	Transcriptional regulator
IM697_RS44215	COG1115	amino acid carrier protein
IM697_RS44225	COG0583	DNA-binding transcription factor activity
IM697_RS44240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_RS44245	COG3938	Belongs to the proline racemase family
IM697_RS44270	COG2226	methyltransferase
IM697_RS44305	COG4213	ABC transporter substrate-binding protein
IM697_RS44320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM697_RS44330	COG2197	response regulator
IM697_RS44335	COG4585	Histidine kinase
IM697_RS44365	COG2205	protein histidine kinase activity
IM697_RS44370	COG0745	RESPONSE REGULATOR receiver
IM697_RS44385	COG1376	ErfK ybiS ycfS ynhG family protein
IM697_RS44390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_RS44410	COG0569	domain protein