locus-tag	class	description
EIZ62_RS00120	COG1309	transcriptional regulator
EIZ62_RS00150	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS00155	COG2172	sigma factor antagonist activity
EIZ62_RS00215	COG1022	Amp-dependent synthetase and ligase
EIZ62_RS00215	COG3320	Male sterility
EIZ62_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EIZ62_RS00240	COG0477	Major facilitator Superfamily
EIZ62_RS00250	COG4977	sequence-specific DNA binding
EIZ62_RS00295	COG1309	transcriptional regulator
EIZ62_RS00300	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS00320	COG0488	(ABC) transporter
EIZ62_RS00345	COG0483	inositol monophosphate 1-phosphatase activity
EIZ62_RS00350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EIZ62_RS00355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EIZ62_RS00375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIZ62_RS00400	COG3226	Transcriptional regulator
EIZ62_RS00435	COG0702	epimerase
EIZ62_RS00440	COG2409	Drug exporters of the RND superfamily
EIZ62_RS00460	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EIZ62_RS00540	COG0596	Alpha beta hydrolase
EIZ62_RS00560	COG1278	Cold shock
EIZ62_RS00610	COG2197	response regulator
EIZ62_RS00615	COG4585	Histidine kinase
EIZ62_RS00650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIZ62_RS00670	COG0583	DNA-binding transcription factor activity
EIZ62_RS00675	COG0667	Aldo Keto reductase
EIZ62_RS00680	COG1470	cell adhesion involved in biofilm formation
EIZ62_RS00745	COG2124	cytochrome p450
EIZ62_RS00760	COG0477	Major facilitator Superfamily
EIZ62_RS00800	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
EIZ62_RS00830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIZ62_RS00835	COG1335	isochorismatase
EIZ62_RS00850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIZ62_RS00870	COG1793	dna ligase
EIZ62_RS00885	COG2018	Roadblock/LC7 domain
EIZ62_RS00955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EIZ62_RS00965	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EIZ62_RS00975	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS00995	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EIZ62_RS00995	COG1672	PFAM Archaeal ATPase
EIZ62_RS01000	COG3291	Pkd domain containing protein
EIZ62_RS01000	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EIZ62_RS01010	COG2197	response regulator
EIZ62_RS01020	COG0726	polysaccharide deacetylase
EIZ62_RS01040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIZ62_RS01050	COG1063	alcohol dehydrogenase
EIZ62_RS01055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EIZ62_RS01060	COG1215	transferase activity, transferring glycosyl groups
EIZ62_RS01065	COG2205	protein histidine kinase activity
EIZ62_RS01070	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS01085	COG1879	ABC-type sugar transport system periplasmic component
EIZ62_RS01090	COG1129	ABC transporter
EIZ62_RS01095	COG1172	Belongs to the binding-protein-dependent transport system permease family
EIZ62_RS01100	COG1733	regulation of RNA biosynthetic process
EIZ62_RS01120	COG1349	DNA-binding transcription factor activity
EIZ62_RS01135	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS01145	COG4948	Mandelate Racemase Muconate Lactonizing
EIZ62_RS01170	COG1940	carbohydrate kinase activity
EIZ62_RS01175	COG1609	Transcriptional regulator
EIZ62_RS01215	COG0583	DNA-binding transcription factor activity
EIZ62_RS01285	COG0583	DNA-binding transcription factor activity
EIZ62_RS01290	COG0697	spore germination
EIZ62_RS01295	COG0640	Transcriptional regulator
EIZ62_RS01310	COG0523	cobalamin synthesis protein
EIZ62_RS01315	COG2249	NAD(P)H dehydrogenase (quinone) activity
EIZ62_RS01325	COG0644	oxidoreductase
EIZ62_RS01330	COG0142	geranyltranstransferase activity
EIZ62_RS01365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EIZ62_RS01375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EIZ62_RS01405	COG4106	trans-aconitate 2-methyltransferase activity
EIZ62_RS01415	COG0662	Cupin 2, conserved barrel domain protein
EIZ62_RS01430	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EIZ62_RS01440	COG1024	Enoyl-CoA hydratase
EIZ62_RS01440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EIZ62_RS01480	COG0375	protein maturation
EIZ62_RS01485	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EIZ62_RS01495	COG0298	carbon dioxide binding
EIZ62_RS01540	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS01545	COG0045	succinate-CoA ligase (ADP-forming) activity
EIZ62_RS01545	COG1042	CoA-binding domain protein
EIZ62_RS01545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EIZ62_RS01555	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EIZ62_RS01570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EIZ62_RS01580	COG1177	transmembrane transport
EIZ62_RS01585	COG3842	ATPase activity
EIZ62_RS01595	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS01625	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
EIZ62_RS01630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EIZ62_RS01720	COG1191	sigma factor activity
EIZ62_RS01725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EIZ62_RS01740	COG1819	glycosyl
EIZ62_RS01745	COG3973	AAA domain
EIZ62_RS01765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EIZ62_RS01780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EIZ62_RS01790	COG2188	Transcriptional regulator
EIZ62_RS01800	COG0431	NADPH-dependent FMN reductase
EIZ62_RS01820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIZ62_RS01870	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS01885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIZ62_RS01885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIZ62_RS01895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIZ62_RS01920	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS01920	COG2172	sigma factor antagonist activity
EIZ62_RS01920	COG2208	phosphoserine phosphatase activity
EIZ62_RS02025	COG1124	(ABC) transporter
EIZ62_RS02035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EIZ62_RS02040	COG0601	transmembrane transport
EIZ62_RS02050	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS02055	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS02065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIZ62_RS02095	COG0642	Histidine kinase
EIZ62_RS02105	COG0277	FAD linked oxidase domain protein
EIZ62_RS02155	COG2706	6-phosphogluconolactonase activity
EIZ62_RS02165	COG3387	PFAM Glycoside hydrolase 15-related
EIZ62_RS02170	COG2409	Drug exporters of the RND superfamily
EIZ62_RS02180	COG1597	lipid kinase activity
EIZ62_RS02185	COG0277	FAD linked oxidase domain protein
EIZ62_RS02210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EIZ62_RS02230	COG3387	PFAM Glycoside hydrolase 15-related
EIZ62_RS02245	COG4935	Belongs to the peptidase S8 family
EIZ62_RS02245	COG2234	aminopeptidase activity
EIZ62_RS02255	COG2340	Cysteine-rich secretory protein family
EIZ62_RS02295	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS02305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIZ62_RS02310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EIZ62_RS02340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIZ62_RS02360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIZ62_RS02360	COG0493	'glutamate synthase
EIZ62_RS02415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIZ62_RS02435	COG0477	Major facilitator Superfamily
EIZ62_RS02440	COG1595	DNA-templated transcription, initiation
EIZ62_RS02475	COG1686	Belongs to the peptidase S11 family
EIZ62_RS02505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EIZ62_RS02520	COG2909	trisaccharide binding
EIZ62_RS02530	COG0477	Major facilitator Superfamily
EIZ62_RS02570	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS02575	COG2205	protein histidine kinase activity
EIZ62_RS02590	COG3511	phospholipase C
EIZ62_RS02610	COG1136	(ABC) transporter
EIZ62_RS02615	COG4585	Histidine kinase
EIZ62_RS02620	COG2197	response regulator
EIZ62_RS02640	COG2268	Band 7 protein
EIZ62_RS02650	COG0659	secondary active sulfate transmembrane transporter activity
EIZ62_RS02665	COG1132	(ABC) transporter
EIZ62_RS02740	COG3568	Endonuclease Exonuclease Phosphatase
EIZ62_RS02775	COG2188	Transcriptional regulator
EIZ62_RS02845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EIZ62_RS02850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EIZ62_RS02895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EIZ62_RS02990	COG1115	amino acid carrier protein
EIZ62_RS02995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EIZ62_RS03010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EIZ62_RS03020	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EIZ62_RS03025	COG0516	GMP reductase activity
EIZ62_RS03025	COG0517	IMP dehydrogenase activity
EIZ62_RS03035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EIZ62_RS03045	COG0589	response to stress
EIZ62_RS03060	COG0589	response to stress
EIZ62_RS03075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EIZ62_RS03075	COG0574	Belongs to the PEP-utilizing enzyme family
EIZ62_RS03090	COG0517	IMP dehydrogenase activity
EIZ62_RS03090	COG0516	GMP reductase activity
EIZ62_RS03120	COG1063	alcohol dehydrogenase
EIZ62_RS03125	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EIZ62_RS03135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIZ62_RS03165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIZ62_RS03175	COG3540	Alkaline phosphatase
EIZ62_RS03200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIZ62_RS03205	COG0183	Belongs to the thiolase family
EIZ62_RS03215	COG1609	Transcriptional regulator
EIZ62_RS03235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EIZ62_RS03240	COG0121	glutamine amidotransferase
EIZ62_RS03245	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EIZ62_RS03260	COG2182	Extracellular solute-binding protein
EIZ62_RS03265	COG3360	Dodecin
EIZ62_RS03275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIZ62_RS03300	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EIZ62_RS03305	COG1053	succinate dehydrogenase
EIZ62_RS03315	COG0583	DNA-binding transcription factor activity
EIZ62_RS03365	COG0531	amino acid
EIZ62_RS03390	COG3275	phosphorelay sensor kinase activity
EIZ62_RS03395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EIZ62_RS03415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EIZ62_RS03420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EIZ62_RS03425	COG2172	sigma factor antagonist activity
EIZ62_RS03425	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS03425	COG2208	phosphoserine phosphatase activity
EIZ62_RS03460	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EIZ62_RS03465	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EIZ62_RS03505	COG1819	glycosyl
EIZ62_RS03520	COG3585	molybdate ion transport
EIZ62_RS03550	COG0655	NAD(P)H dehydrogenase (quinone) activity
EIZ62_RS03620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIZ62_RS03685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EIZ62_RS03710	COG3135	benzoate transporter
EIZ62_RS03715	COG0626	cystathionine gamma-synthase activity
EIZ62_RS03725	COG2423	ornithine cyclodeaminase activity
EIZ62_RS03730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EIZ62_RS03795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIZ62_RS03805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIZ62_RS03830	COG2197	response regulator
EIZ62_RS03850	COG0318	PFAM AMP-dependent synthetase and ligase
EIZ62_RS03870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIZ62_RS03875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EIZ62_RS03895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EIZ62_RS03910	COG0596	Alpha beta hydrolase
EIZ62_RS03925	COG0646	methionine synthase
EIZ62_RS03925	COG1410	methionine synthase
EIZ62_RS03930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIZ62_RS03935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EIZ62_RS03970	COG2130	NADP-dependent
EIZ62_RS04015	COG0477	Major facilitator Superfamily
EIZ62_RS04020	COG2130	NADP-dependent
EIZ62_RS04040	COG2318	DinB family
EIZ62_RS04090	COG0583	DNA-binding transcription factor activity
EIZ62_RS04095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EIZ62_RS04115	COG3959	Transketolase, thiamine diphosphate binding domain
EIZ62_RS04120	COG3958	Transketolase
EIZ62_RS04130	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS04165	COG1595	DNA-templated transcription, initiation
EIZ62_RS04175	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EIZ62_RS04180	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EIZ62_RS04185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EIZ62_RS04225	COG0577	efflux transmembrane transporter activity
EIZ62_RS04225	COG1136	(ABC) transporter
EIZ62_RS04230	COG4585	Histidine kinase
EIZ62_RS04235	COG2197	response regulator
EIZ62_RS04255	COG2755	lipolytic protein G-D-S-L family
EIZ62_RS04265	COG2365	Tyrosine phosphatase family
EIZ62_RS04280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EIZ62_RS04285	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EIZ62_RS04295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EIZ62_RS04300	COG1657	PFAM Prenyltransferase squalene oxidase
EIZ62_RS04310	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EIZ62_RS04325	COG1134	teichoic acid transport
EIZ62_RS04325	COG1388	LysM domain
EIZ62_RS04345	COG0371	Dehydrogenase
EIZ62_RS04375	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EIZ62_RS04385	COG1024	Enoyl-CoA hydratase
EIZ62_RS04395	COG4977	sequence-specific DNA binding
EIZ62_RS04405	COG2183	response to ionizing radiation
EIZ62_RS04415	COG0488	(ABC) transporter
EIZ62_RS04450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EIZ62_RS04460	COG2936	dipeptidyl-peptidase activity
EIZ62_RS04495	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS04510	COG3568	Endonuclease Exonuclease Phosphatase
EIZ62_RS04525	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIZ62_RS04525	COG1024	Enoyl-CoA hydratase
EIZ62_RS04530	COG0183	Belongs to the thiolase family
EIZ62_RS04535	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS04540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EIZ62_RS04545	COG3268	Saccharopine dehydrogenase
EIZ62_RS04550	COG1515	deoxyribonuclease V activity
EIZ62_RS04570	COG0488	(ABC) transporter
EIZ62_RS04575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EIZ62_RS04580	COG1834	amidinotransferase
EIZ62_RS04635	COG1793	dna ligase
EIZ62_RS04695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EIZ62_RS04705	COG1127	ABC transporter
EIZ62_RS04730	COG3012	SEC-C Motif Domain Protein
EIZ62_RS04745	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EIZ62_RS04750	COG1486	melibiose metabolic process
EIZ62_RS04785	COG1404	Belongs to the peptidase S8 family
EIZ62_RS04810	COG2040	homocysteine
EIZ62_RS04850	COG0247	lactate metabolic process
EIZ62_RS04855	COG1139	Iron-sulfur cluster binding protein
EIZ62_RS04860	COG1556	Lactate utilization protein
EIZ62_RS04865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIZ62_RS04870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EIZ62_RS04885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIZ62_RS04915	COG2274	protein secretion by the type I secretion system
EIZ62_RS04965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EIZ62_RS04995	COG1172	Belongs to the binding-protein-dependent transport system permease family
EIZ62_RS05000	COG1129	ABC transporter
EIZ62_RS05010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIZ62_RS05015	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EIZ62_RS05030	COG0583	DNA-binding transcription factor activity
EIZ62_RS05040	COG0656	L-ascorbic acid biosynthetic process
EIZ62_RS05045	COG0701	Predicted permease
EIZ62_RS05055	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EIZ62_RS05060	COG2154	pterin-4-alpha-carbinolamine dehydratase
EIZ62_RS05080	COG1063	alcohol dehydrogenase
EIZ62_RS05085	COG0156	8-amino-7-oxononanoate synthase activity
EIZ62_RS05115	COG0531	amino acid
EIZ62_RS05150	COG0028	Belongs to the TPP enzyme family
EIZ62_RS05160	COG0693	protein deglycase activity
EIZ62_RS05220	COG1793	dna ligase
EIZ62_RS05220	COG3285	dna ligase
EIZ62_RS05230	COG3959	Transketolase, thiamine diphosphate binding domain
EIZ62_RS05235	COG1252	NADH dehydrogenase
EIZ62_RS05240	COG2226	methyltransferase
EIZ62_RS05325	COG0477	Major facilitator Superfamily
EIZ62_RS05335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EIZ62_RS05340	COG0628	permease
EIZ62_RS05345	COG1619	proteins homologs of microcin C7 resistance protein MccF
EIZ62_RS05355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIZ62_RS05360	COG2362	D-Aminopeptidase
EIZ62_RS05385	COG0596	Alpha beta hydrolase
EIZ62_RS05400	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIZ62_RS05410	COG0604	alcohol dehydrogenase
EIZ62_RS05415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIZ62_RS05415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIZ62_RS05420	COG2301	Belongs to the HpcH HpaI aldolase family
EIZ62_RS05430	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS05435	COG0688	phosphatidylethanolamine metabolic process
EIZ62_RS05455	COG1929	Belongs to the glycerate kinase type-1 family
EIZ62_RS05475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EIZ62_RS05480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EIZ62_RS05505	COG0483	inositol monophosphate 1-phosphatase activity
EIZ62_RS05520	COG0095	Lipoate-protein ligase
EIZ62_RS05535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EIZ62_RS05540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIZ62_RS05575	COG2233	PERMEase
EIZ62_RS05580	COG0402	S-adenosylhomocysteine deaminase activity
EIZ62_RS05590	COG1609	Transcriptional regulator
EIZ62_RS05595	COG0405	Gamma-glutamyltransferase
EIZ62_RS05605	COG0789	Transcriptional regulator
EIZ62_RS05615	COG1376	ErfK ybiS ycfS ynhG family protein
EIZ62_RS05625	COG0765	amino acid transport
EIZ62_RS05630	COG0765	amino acid transport
EIZ62_RS05635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIZ62_RS05640	COG1126	abc transporter atp-binding protein
EIZ62_RS05660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIZ62_RS05675	COG1940	carbohydrate kinase activity
EIZ62_RS05700	COG2188	Transcriptional regulator
EIZ62_RS05705	COG0673	inositol 2-dehydrogenase activity
EIZ62_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS05725	COG4266	Belongs to the allantoicase family
EIZ62_RS05730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EIZ62_RS05735	COG1414	Transcriptional regulator
EIZ62_RS05765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EIZ62_RS05770	COG4733	cellulase activity
EIZ62_RS05770	COG5297	Belongs to the glycosyl hydrolase family 6
EIZ62_RS05795	COG2233	PERMEase
EIZ62_RS05805	COG2233	PERMEase
EIZ62_RS05815	COG2351	hydroxyisourate hydrolase activity
EIZ62_RS05835	COG3622	Belongs to the hyi family
EIZ62_RS05840	COG2084	Dehydrogenase
EIZ62_RS05845	COG0753	catalase activity
EIZ62_RS05900	COG3960	tartronate-semialdehyde synthase activity
EIZ62_RS05910	COG0318	PFAM AMP-dependent synthetase and ligase
EIZ62_RS05915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EIZ62_RS05945	COG0598	Magnesium transport protein CorA
EIZ62_RS05990	COG0765	amino acid transport
EIZ62_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS06010	COG0151	Belongs to the GarS family
EIZ62_RS06015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIZ62_RS06030	COG0529	Catalyzes the synthesis of activated sulfate
EIZ62_RS06035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EIZ62_RS06040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EIZ62_RS06050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EIZ62_RS06055	COG3959	Transketolase, thiamine diphosphate binding domain
EIZ62_RS06060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EIZ62_RS06080	COG0189	ligase activity
EIZ62_RS06085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIZ62_RS06105	COG2197	response regulator
EIZ62_RS06110	COG1834	amidinotransferase
EIZ62_RS06140	COG1120	ATPase activity
EIZ62_RS06155	COG0477	Major facilitator Superfamily
EIZ62_RS06175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EIZ62_RS06190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EIZ62_RS06205	COG2066	Belongs to the glutaminase family
EIZ62_RS06210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EIZ62_RS06215	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EIZ62_RS06220	COG2080	2 iron, 2 sulfur cluster binding
EIZ62_RS06230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EIZ62_RS06235	COG4552	Acetyltransferase involved in intracellular survival and related
EIZ62_RS06245	COG2252	PERMEase
EIZ62_RS06250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EIZ62_RS06270	COG1357	PFAM Pentapeptide repeats (8 copies)
EIZ62_RS06285	COG1802	Transcriptional regulator
EIZ62_RS06305	COG0028	Belongs to the TPP enzyme family
EIZ62_RS06330	COG1162	GTPase activity
EIZ62_RS06350	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS06375	COG0175	sulfate reduction
EIZ62_RS06380	COG0529	Catalyzes the synthesis of activated sulfate
EIZ62_RS06400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EIZ62_RS06400	COG1116	anion transmembrane transporter activity
EIZ62_RS06405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EIZ62_RS06440	COG1175	transmembrane transport
EIZ62_RS06490	COG0346	lactoylglutathione lyase activity
EIZ62_RS06515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EIZ62_RS06520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIZ62_RS06550	COG2124	cytochrome p450
EIZ62_RS06560	COG0667	Aldo Keto reductase
EIZ62_RS06585	COG3220	belongs to the UPF0276 family
EIZ62_RS06605	COG3253	May function as heme-dependent peroxidase
EIZ62_RS06610	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EIZ62_RS06615	COG0446	pyridine nucleotide-disulphide oxidoreductase
EIZ62_RS06625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EIZ62_RS06640	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EIZ62_RS06645	COG0183	Belongs to the thiolase family
EIZ62_RS06650	COG1024	Enoyl-CoA hydratase
EIZ62_RS06650	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIZ62_RS06655	COG0514	ATP-dependent DNA helicase (RecQ)
EIZ62_RS06660	COG0531	amino acid
EIZ62_RS06665	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EIZ62_RS06670	COG4214	carbohydrate transport
EIZ62_RS06680	COG4213	ABC transporter substrate-binding protein
EIZ62_RS06685	COG1940	carbohydrate kinase activity
EIZ62_RS06690	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS06695	COG1175	transmembrane transport
EIZ62_RS06700	COG1653	transport
EIZ62_RS06710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EIZ62_RS06730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EIZ62_RS06750	COG1063	alcohol dehydrogenase
EIZ62_RS06760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EIZ62_RS06765	COG0546	phosphoglycolate phosphatase activity
EIZ62_RS06775	COG1349	DNA-binding transcription factor activity
EIZ62_RS06800	COG0297	glycogen (starch) synthase activity
EIZ62_RS06810	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS06830	COG3938	Belongs to the proline racemase family
EIZ62_RS06870	COG3226	Transcriptional regulator
EIZ62_RS06905	COG1024	Enoyl-CoA hydratase
EIZ62_RS06915	COG0531	amino acid
EIZ62_RS06920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EIZ62_RS06930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EIZ62_RS06965	COG1799	cell septum assembly
EIZ62_RS06975	COG1175	transmembrane transport
EIZ62_RS06980	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS07000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIZ62_RS07035	COG4948	Mandelate Racemase Muconate Lactonizing
EIZ62_RS07060	COG1309	transcriptional regulator
EIZ62_RS07075	COG2207	Transcriptional regulator
EIZ62_RS07145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EIZ62_RS07150	COG0531	amino acid
EIZ62_RS07155	COG0569	domain protein
EIZ62_RS07190	COG0756	dUTP diphosphatase activity
EIZ62_RS07215	COG2205	protein histidine kinase activity
EIZ62_RS07220	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS07235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EIZ62_RS07270	COG1435	thymidine kinase activity
EIZ62_RS07285	COG0045	succinate-CoA ligase (ADP-forming) activity
EIZ62_RS07285	COG1042	CoA-binding domain protein
EIZ62_RS07285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EIZ62_RS07290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIZ62_RS07295	COG1802	Transcriptional regulator
EIZ62_RS07310	COG0612	Peptidase, M16
EIZ62_RS07315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EIZ62_RS07330	COG3290	protein histidine kinase activity
EIZ62_RS07335	COG4565	transcriptional regulatory protein
EIZ62_RS07340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EIZ62_RS07365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EIZ62_RS07370	COG2186	Transcriptional regulator
EIZ62_RS07395	COG0514	ATP-dependent DNA helicase (RecQ)
EIZ62_RS07410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EIZ62_RS07425	COG0406	alpha-ribazole phosphatase activity
EIZ62_RS07445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EIZ62_RS07450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EIZ62_RS07455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EIZ62_RS07495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EIZ62_RS07505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIZ62_RS07510	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EIZ62_RS07520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EIZ62_RS07535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIZ62_RS07545	COG0531	amino acid
EIZ62_RS07550	COG2124	cytochrome p450
EIZ62_RS07565	COG2205	protein histidine kinase activity
EIZ62_RS07575	COG1126	abc transporter atp-binding protein
EIZ62_RS07585	COG0765	amino acid transport
EIZ62_RS07590	COG0765	amino acid transport
EIZ62_RS07595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIZ62_RS07605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIZ62_RS07615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EIZ62_RS07620	COG0628	permease
EIZ62_RS07650	COG1201	RNA secondary structure unwinding
EIZ62_RS07655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EIZ62_RS07660	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS07670	COG0783	Belongs to the Dps family
EIZ62_RS07675	COG1396	sequence-specific DNA binding
EIZ62_RS07680	COG1058	Belongs to the CinA family
EIZ62_RS07680	COG1546	Belongs to the CinA family
EIZ62_RS07690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIZ62_RS07700	COG1674	ftsk spoiiie
EIZ62_RS07710	COG2205	protein histidine kinase activity
EIZ62_RS07710	COG3437	response regulator, receiver
EIZ62_RS07710	COG3850	Histidine kinase
EIZ62_RS07710	COG2205	protein histidine kinase activity
EIZ62_RS07710	COG3437	response regulator, receiver
EIZ62_RS07710	COG3850	Histidine kinase
EIZ62_RS07710	COG4999	Histidine kinase
EIZ62_RS07710	COG4999	Histidine kinase
EIZ62_RS07715	COG2770	Histidine kinase
EIZ62_RS07715	COG2208	phosphoserine phosphatase activity
EIZ62_RS07740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EIZ62_RS07745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EIZ62_RS07750	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EIZ62_RS07770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EIZ62_RS07775	COG0612	Peptidase, M16
EIZ62_RS07780	COG1185	polyribonucleotide nucleotidyltransferase activity
EIZ62_RS07785	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EIZ62_RS07795	COG1674	ftsk spoiiie
EIZ62_RS07825	COG0515	serine threonine protein kinase
EIZ62_RS07825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EIZ62_RS07845	COG1404	Belongs to the peptidase S8 family
EIZ62_RS07860	COG1404	Belongs to the peptidase S8 family
EIZ62_RS07865	COG3266	domain, Protein
EIZ62_RS07885	COG0455	bacterial-type flagellum organization
EIZ62_RS07895	COG0601	transmembrane transport
EIZ62_RS07900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EIZ62_RS07905	COG0444	Belongs to the ABC transporter superfamily
EIZ62_RS07910	COG4608	Belongs to the ABC transporter superfamily
EIZ62_RS07925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EIZ62_RS07930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EIZ62_RS07940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EIZ62_RS07955	COG0779	Required for maturation of 30S ribosomal subunits
EIZ62_RS07975	COG0330	HflC and HflK could
EIZ62_RS07980	COG0442	prolyl-tRNA aminoacylation
EIZ62_RS07995	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EIZ62_RS08000	COG0750	zinc metalloprotease
EIZ62_RS08005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EIZ62_RS08010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EIZ62_RS08020	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS08025	COG0697	spore germination
EIZ62_RS08030	COG2508	Transcriptional regulator
EIZ62_RS08055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIZ62_RS08060	COG1177	transmembrane transport
EIZ62_RS08065	COG1176	ABC-type spermidine putrescine transport system, permease component I
EIZ62_RS08070	COG3842	ATPase activity
EIZ62_RS08075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EIZ62_RS08080	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS08095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EIZ62_RS08100	COG0584	glycerophosphoryl diester phosphodiesterase
EIZ62_RS08130	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS08140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EIZ62_RS08145	COG1136	(ABC) transporter
EIZ62_RS08165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIZ62_RS08170	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS08190	COG2197	response regulator
EIZ62_RS08200	COG2205	protein histidine kinase activity
EIZ62_RS08205	COG3842	ATPase activity
EIZ62_RS08210	COG4208	sulfate ABC transporter
EIZ62_RS08220	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EIZ62_RS08225	COG0575	Belongs to the CDS family
EIZ62_RS08230	COG0233	cytoplasmic translational termination
EIZ62_RS08235	COG0528	UMP kinase activity
EIZ62_RS08240	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EIZ62_RS08245	COG0052	Belongs to the universal ribosomal protein uS2 family
EIZ62_RS08250	COG4942	peptidase
EIZ62_RS08250	COG1388	LysM domain
EIZ62_RS08260	COG1191	sigma factor activity
EIZ62_RS08275	COG0792	nuclease activity
EIZ62_RS08290	COG0681	Belongs to the peptidase S26 family
EIZ62_RS08300	COG0681	Belongs to the peptidase S26 family
EIZ62_RS08310	COG0335	large ribosomal subunit rRNA binding
EIZ62_RS08315	COG0336	Belongs to the RNA methyltransferase TrmD family
EIZ62_RS08320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EIZ62_RS08325	COG1837	Belongs to the UPF0109 family
EIZ62_RS08330	COG0228	four-way junction DNA binding
EIZ62_RS08345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIZ62_RS08355	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EIZ62_RS08385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EIZ62_RS08395	COG0477	Major facilitator Superfamily
EIZ62_RS08400	COG1196	nuclear chromosome segregation
EIZ62_RS08415	COG1254	Belongs to the acylphosphatase family
EIZ62_RS08420	COG2340	Cysteine-rich secretory protein family
EIZ62_RS08425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EIZ62_RS08430	COG0571	ribonuclease III activity
EIZ62_RS08435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EIZ62_RS08450	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EIZ62_RS08455	COG0742	ribosomal rna small subunit methyltransferase
EIZ62_RS08465	COG1461	Dihydroxyacetone kinase
EIZ62_RS08470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EIZ62_RS08475	COG0351	phosphomethylpyrimidine kinase
EIZ62_RS08495	COG1181	Belongs to the D-alanine--D-alanine ligase family
EIZ62_RS08500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EIZ62_RS08510	COG1920	GTP binding
EIZ62_RS08520	COG0776	regulation of translation
EIZ62_RS08530	COG0066	3-isopropylmalate dehydratase activity
EIZ62_RS08535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EIZ62_RS08540	COG1414	Transcriptional regulator
EIZ62_RS08575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EIZ62_RS08580	COG0179	Fumarylacetoacetate (FAA) hydrolase
EIZ62_RS08590	COG5002	protein histidine kinase activity
EIZ62_RS08595	COG2018	Roadblock/LC7 domain
EIZ62_RS08615	COG2018	Roadblock/LC7 domain
EIZ62_RS08635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIZ62_RS08645	COG0366	Alpha amylase catalytic
EIZ62_RS08645	COG1470	cell adhesion involved in biofilm formation
EIZ62_RS08670	COG0714	Associated with various cellular activities
EIZ62_RS08680	COG2353	YceI-like domain
EIZ62_RS08725	COG0667	Aldo Keto reductase
EIZ62_RS08760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EIZ62_RS08770	COG2957	Belongs to the agmatine deiminase family
EIZ62_RS08775	COG0804	urea catabolic process
EIZ62_RS08780	COG0832	Belongs to the urease beta subunit family
EIZ62_RS08780	COG0831	urea catabolic process
EIZ62_RS08790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EIZ62_RS08795	COG0473	3-isopropylmalate dehydrogenase activity
EIZ62_RS08810	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS08815	COG0506	proline dehydrogenase activity
EIZ62_RS08820	COG3835	regulator
EIZ62_RS08825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EIZ62_RS08830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EIZ62_RS08835	COG0440	acetolactate synthase activity
EIZ62_RS08855	COG0667	Aldo Keto reductase
EIZ62_RS08860	COG2133	pyrroloquinoline quinone binding
EIZ62_RS08870	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EIZ62_RS08870	COG1672	PFAM Archaeal ATPase
EIZ62_RS08885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EIZ62_RS08890	COG2409	Drug exporters of the RND superfamily
EIZ62_RS08900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EIZ62_RS08910	COG0154	amidase activity
EIZ62_RS08915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EIZ62_RS08925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EIZ62_RS08970	COG0482	sulfurtransferase activity
EIZ62_RS08990	COG1309	transcriptional regulator
EIZ62_RS09000	COG2860	membrane
EIZ62_RS09010	COG4608	Belongs to the ABC transporter superfamily
EIZ62_RS09015	COG0444	Belongs to the ABC transporter superfamily
EIZ62_RS09025	COG4166	transmembrane transport
EIZ62_RS09030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EIZ62_RS09050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EIZ62_RS09055	COG0509	glycine decarboxylation via glycine cleavage system
EIZ62_RS09060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EIZ62_RS09065	COG1760	l-serine dehydratase
EIZ62_RS09115	COG2197	response regulator
EIZ62_RS09130	COG1131	(ABC) transporter
EIZ62_RS09135	COG1132	(ABC) transporter
EIZ62_RS09140	COG1132	(ABC) transporter
EIZ62_RS09155	COG0058	SHG alpha-glucan phosphorylase activity
EIZ62_RS09180	COG2368	4-hydroxyphenylacetate
EIZ62_RS09195	COG0366	Alpha amylase catalytic
EIZ62_RS09210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIZ62_RS09220	COG1522	sequence-specific DNA binding
EIZ62_RS09235	COG0477	Major facilitator Superfamily
EIZ62_RS09250	COG1301	dicarboxylic acid transport
EIZ62_RS09255	COG3290	protein histidine kinase activity
EIZ62_RS09260	COG4565	transcriptional regulatory protein
EIZ62_RS09270	COG0205	6-phosphofructokinase activity
EIZ62_RS09275	COG0280	phosphate acetyltransferase
EIZ62_RS09275	COG0857	belongs to the CobB CobQ family
EIZ62_RS09280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EIZ62_RS09325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIZ62_RS09335	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS09360	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIZ62_RS09360	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIZ62_RS09435	COG1073	alpha beta
EIZ62_RS09435	COG2226	methyltransferase
EIZ62_RS09445	COG0183	Belongs to the thiolase family
EIZ62_RS09520	COG3321	synthase
EIZ62_RS09520	COG0604	alcohol dehydrogenase
EIZ62_RS09525	COG0604	alcohol dehydrogenase
EIZ62_RS09525	COG3321	synthase
EIZ62_RS09555	COG4638	Rieske (2fe-2S)
EIZ62_RS09585	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EIZ62_RS09600	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIZ62_RS09635	COG2197	response regulator
EIZ62_RS09655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EIZ62_RS09660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EIZ62_RS09665	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EIZ62_RS09670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EIZ62_RS09675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIZ62_RS09680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EIZ62_RS09685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIZ62_RS09700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EIZ62_RS09705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EIZ62_RS09710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EIZ62_RS09720	COG2890	protein-(glutamine-N5) methyltransferase activity
EIZ62_RS09725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EIZ62_RS09730	COG0254	rRNA binding
EIZ62_RS09750	COG0083	homoserine kinase activity
EIZ62_RS09755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EIZ62_RS09760	COG0460	homoserine dehydrogenase
EIZ62_RS09765	COG0019	diaminopimelate decarboxylase activity
EIZ62_RS09770	COG0018	arginyl-trna synthetase
EIZ62_RS09855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EIZ62_RS09880	COG1733	regulation of RNA biosynthetic process
EIZ62_RS09890	COG2897	thiosulfate sulfurtransferase activity
EIZ62_RS09905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EIZ62_RS09920	COG0492	ferredoxin-NADP+ reductase activity
EIZ62_RS09940	COG0693	protein deglycase activity
EIZ62_RS09950	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS09970	COG2770	Histidine kinase
EIZ62_RS09970	COG2208	phosphoserine phosphatase activity
EIZ62_RS09975	COG2894	cell division
EIZ62_RS09980	COG0366	Alpha amylase catalytic
EIZ62_RS10000	COG0475	glutathione-regulated potassium exporter activity
EIZ62_RS10055	COG2814	Major facilitator Superfamily
EIZ62_RS10070	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS10075	COG0297	glycogen (starch) synthase activity
EIZ62_RS10080	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EIZ62_RS10085	COG3285	dna ligase
EIZ62_RS10085	COG1793	dna ligase
EIZ62_RS10115	COG2205	protein histidine kinase activity
EIZ62_RS10145	COG1309	transcriptional regulator
EIZ62_RS10160	COG0791	NLP P60 protein
EIZ62_RS10160	COG3883	PFAM NLP P60 protein
EIZ62_RS10165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EIZ62_RS10170	COG0697	spore germination
EIZ62_RS10190	COG2154	pterin-4-alpha-carbinolamine dehydratase
EIZ62_RS10240	COG1846	Transcriptional regulator
EIZ62_RS10245	COG3227	Zinc metalloprotease (Elastase)
EIZ62_RS10260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EIZ62_RS10290	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS10295	COG2205	protein histidine kinase activity
EIZ62_RS10300	COG0567	Dehydrogenase, E1 component
EIZ62_RS10300	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIZ62_RS10320	COG1695	Transcriptional regulator
EIZ62_RS10345	COG0604	alcohol dehydrogenase
EIZ62_RS10350	COG3540	Alkaline phosphatase
EIZ62_RS10360	COG0281	malic enzyme
EIZ62_RS10365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIZ62_RS10370	COG0765	amino acid transport
EIZ62_RS10375	COG1126	abc transporter atp-binding protein
EIZ62_RS10380	COG2226	methyltransferase
EIZ62_RS10460	COG0142	geranyltranstransferase activity
EIZ62_RS10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIZ62_RS10475	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EIZ62_RS10505	COG1597	lipid kinase activity
EIZ62_RS10520	COG0363	glucosamine-6-phosphate deaminase activity
EIZ62_RS10525	COG1472	Belongs to the glycosyl hydrolase 3 family
EIZ62_RS10530	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS10535	COG1175	transmembrane transport
EIZ62_RS10540	COG2182	Extracellular solute-binding protein
EIZ62_RS10545	COG2188	Transcriptional regulator
EIZ62_RS10585	COG0242	peptide deformylase activity
EIZ62_RS10600	COG2199	diguanylate cyclase activity
EIZ62_RS10600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EIZ62_RS10605	COG5662	AntiSigma factor
EIZ62_RS10610	COG1595	DNA-templated transcription, initiation
EIZ62_RS10620	COG2135	peptidase activity
EIZ62_RS10630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EIZ62_RS10635	COG1162	GTPase activity
EIZ62_RS10640	COG2076	Multidrug Resistance protein
EIZ62_RS10650	COG0483	inositol monophosphate 1-phosphatase activity
EIZ62_RS10660	COG0753	catalase activity
EIZ62_RS10685	COG1615	UPF0182 protein
EIZ62_RS10695	COG3480	Lon protease (S16) C-terminal proteolytic domain
EIZ62_RS10745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EIZ62_RS10785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIZ62_RS10790	COG0210	DNA helicase
EIZ62_RS10850	COG0596	Alpha beta hydrolase
EIZ62_RS10880	COG0513	Belongs to the DEAD box helicase family
EIZ62_RS10890	COG1432	Conserved Protein
EIZ62_RS10900	COG2095	MarC family integral membrane protein
EIZ62_RS10915	COG2814	Major facilitator Superfamily
EIZ62_RS10925	COG0598	Magnesium transport protein CorA
EIZ62_RS10960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIZ62_RS10965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIZ62_RS10975	COG1595	DNA-templated transcription, initiation
EIZ62_RS10990	COG1024	Enoyl-CoA hydratase
EIZ62_RS10995	COG2818	Glycosylase
EIZ62_RS11005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EIZ62_RS11010	COG1611	Belongs to the LOG family
EIZ62_RS11015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIZ62_RS11070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EIZ62_RS11085	COG4608	Belongs to the ABC transporter superfamily
EIZ62_RS11095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EIZ62_RS11100	COG0601	transmembrane transport
EIZ62_RS11110	COG4608	Belongs to the ABC transporter superfamily
EIZ62_RS11115	COG0444	Belongs to the ABC transporter superfamily
EIZ62_RS11120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EIZ62_RS11125	COG0601	transmembrane transport
EIZ62_RS11135	COG1217	gtp-binding protein TYPA
EIZ62_RS11220	COG2197	response regulator
EIZ62_RS11240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EIZ62_RS11255	COG0012	GTP binding
EIZ62_RS11270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EIZ62_RS11275	COG0531	amino acid
EIZ62_RS11280	COG1570	exodeoxyribonuclease VII activity
EIZ62_RS11285	COG1722	exodeoxyribonuclease VII activity
EIZ62_RS11290	COG0778	Nitroreductase
EIZ62_RS11315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EIZ62_RS11315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EIZ62_RS11325	COG0114	fumarate hydratase activity
EIZ62_RS11340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIZ62_RS11375	COG0450	alkyl hydroperoxide reductase
EIZ62_RS11380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIZ62_RS11400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EIZ62_RS11405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EIZ62_RS11410	COG0667	Aldo Keto reductase
EIZ62_RS11460	COG2885	chlorophyll binding
EIZ62_RS11480	COG2197	response regulator
EIZ62_RS11550	COG2610	gluconate transmembrane transporter activity
EIZ62_RS11560	COG1414	Transcriptional regulator
EIZ62_RS11575	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EIZ62_RS11610	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS11630	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EIZ62_RS11640	COG1309	transcriptional regulator
EIZ62_RS11650	COG0463	Glycosyl transferase, family 2
EIZ62_RS11665	COG1331	Highly conserved protein containing a thioredoxin domain
EIZ62_RS11680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EIZ62_RS11690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIZ62_RS11705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EIZ62_RS11715	COG1595	DNA-templated transcription, initiation
EIZ62_RS11735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EIZ62_RS11745	COG0488	(ABC) transporter
EIZ62_RS11755	COG1376	ErfK ybiS ycfS ynhG family protein
EIZ62_RS11770	COG2986	histidine ammonia-lyase
EIZ62_RS11780	COG1024	Enoyl-CoA hydratase
EIZ62_RS11795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIZ62_RS11820	COG0424	maF-like protein
EIZ62_RS11830	COG4770	biotin carboxylase activity
EIZ62_RS11860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIZ62_RS11875	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EIZ62_RS11880	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS11885	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS11900	COG1595	DNA-templated transcription, initiation
EIZ62_RS11905	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS11910	COG2205	protein histidine kinase activity
EIZ62_RS11935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EIZ62_RS11945	COG0583	DNA-binding transcription factor activity
EIZ62_RS11950	COG2814	Major facilitator Superfamily
EIZ62_RS11985	COG1079	Belongs to the binding-protein-dependent transport system permease family
EIZ62_RS11995	COG3845	ABC transporter
EIZ62_RS12000	COG1744	ABC transporter substrate-binding protein PnrA-like
EIZ62_RS12005	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EIZ62_RS12005	COG1473	amidohydrolase
EIZ62_RS12015	COG2089	acid synthase
EIZ62_RS12020	COG1083	cytidylyl-transferase
EIZ62_RS12030	COG1216	Glycosyl transferase, family 2
EIZ62_RS12050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIZ62_RS12050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIZ62_RS12065	COG1595	DNA-templated transcription, initiation
EIZ62_RS12080	COG1595	DNA-templated transcription, initiation
EIZ62_RS12115	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EIZ62_RS12115	COG3064	Membrane
EIZ62_RS12115	COG3583	domain protein
EIZ62_RS12125	COG2009	succinate dehydrogenase
EIZ62_RS12135	COG1053	succinate dehydrogenase
EIZ62_RS12140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EIZ62_RS12145	COG2124	cytochrome p450
EIZ62_RS12165	COG1309	transcriptional regulator
EIZ62_RS12170	COG1408	metallophosphoesterase
EIZ62_RS12180	COG1686	Belongs to the peptidase S11 family
EIZ62_RS12185	COG1295	ribonuclease BN
EIZ62_RS12220	COG0180	Tryptophanyl-tRNA synthetase
EIZ62_RS12225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EIZ62_RS12230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIZ62_RS12235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EIZ62_RS12240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIZ62_RS12255	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS12255	COG2172	sigma factor antagonist activity
EIZ62_RS12255	COG2208	phosphoserine phosphatase activity
EIZ62_RS12285	COG0517	IMP dehydrogenase activity
EIZ62_RS12285	COG4175	Glycine betaine
EIZ62_RS12295	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS12305	COG1476	TRANSCRIPTIONal
EIZ62_RS12310	COG2755	lipolytic protein G-D-S-L family
EIZ62_RS12310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EIZ62_RS12315	COG0039	L-malate dehydrogenase activity
EIZ62_RS12325	COG0538	isocitrate dehydrogenase activity
EIZ62_RS12335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EIZ62_RS12345	COG0138	bifunctional purine biosynthesis protein purh
EIZ62_RS12375	COG0045	succinate-CoA ligase (ADP-forming) activity
EIZ62_RS12380	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EIZ62_RS12390	COG0714	Associated with various cellular activities
EIZ62_RS12410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIZ62_RS12420	COG0739	heme binding
EIZ62_RS12450	COG2197	response regulator
EIZ62_RS12485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EIZ62_RS12485	COG0519	Catalyzes the synthesis of GMP from XMP
EIZ62_RS12510	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS12515	COG0515	serine threonine protein kinase
EIZ62_RS12520	COG0515	serine threonine protein kinase
EIZ62_RS12535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EIZ62_RS12550	COG0516	GMP reductase activity
EIZ62_RS12560	COG1595	DNA-templated transcription, initiation
EIZ62_RS12575	COG0583	DNA-binding transcription factor activity
EIZ62_RS12585	COG4221	oxidoreductase activity
EIZ62_RS12590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EIZ62_RS12600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EIZ62_RS12605	COG0726	polysaccharide deacetylase
EIZ62_RS12620	COG4941	Belongs to the sigma-70 factor family
EIZ62_RS12640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EIZ62_RS12665	COG0802	atpase or kinase
EIZ62_RS12675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EIZ62_RS12685	COG0736	holo-[acyl-carrier-protein] synthase activity
EIZ62_RS12690	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EIZ62_RS12705	COG1072	(Pantothenic acid kinase))
EIZ62_RS12715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIZ62_RS12720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EIZ62_RS12725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EIZ62_RS12730	COG0488	(ABC) transporter
EIZ62_RS12740	COG0101	tRNA pseudouridine synthase activity
EIZ62_RS12745	COG0203	ribosomal protein L17
EIZ62_RS12750	COG0202	RNA polymerase activity
EIZ62_RS12755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EIZ62_RS12760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EIZ62_RS12765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EIZ62_RS12770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EIZ62_RS12780	COG0563	adenylate kinase activity
EIZ62_RS12790	COG0200	Binds to the 23S rRNA
EIZ62_RS12795	COG1841	ribosomal large subunit assembly
EIZ62_RS12800	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EIZ62_RS12805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EIZ62_RS12810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EIZ62_RS12815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EIZ62_RS12825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EIZ62_RS12830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EIZ62_RS12835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EIZ62_RS12840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EIZ62_RS12845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EIZ62_RS12850	COG0255	Belongs to the universal ribosomal protein uL29 family
EIZ62_RS12855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EIZ62_RS12860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EIZ62_RS12865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EIZ62_RS12870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EIZ62_RS12875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EIZ62_RS12880	COG0089	rRNA binding
EIZ62_RS12885	COG0088	Forms part of the polypeptide exit tunnel
EIZ62_RS12890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EIZ62_RS12895	COG0051	transcription antitermination factor activity, RNA binding
EIZ62_RS12945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIZ62_RS12950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EIZ62_RS12955	COG0049	tRNA binding
EIZ62_RS12960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EIZ62_RS12995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EIZ62_RS13000	COG0085	RNA polymerase activity
EIZ62_RS13005	COG0222	ribosome binding
EIZ62_RS13015	COG0081	regulation of translation
EIZ62_RS13020	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EIZ62_RS13040	COG0436	Aminotransferase
EIZ62_RS13045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EIZ62_RS13050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EIZ62_RS13060	COG2030	dehydratase
EIZ62_RS13065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EIZ62_RS13080	COG0402	S-adenosylhomocysteine deaminase activity
EIZ62_RS13085	COG0702	epimerase
EIZ62_RS13100	COG1666	GTP binding
EIZ62_RS13105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EIZ62_RS13115	COG2261	transglycosylase associated protein
EIZ62_RS13125	COG3304	Inner membrane component domain
EIZ62_RS13130	COG0501	Belongs to the peptidase M48B family
EIZ62_RS13135	COG1970	mechanosensitive ion channel activity
EIZ62_RS13140	COG1007	ATP synthesis coupled electron transport
EIZ62_RS13155	COG0713	ATP synthesis coupled electron transport
EIZ62_RS13170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EIZ62_RS13180	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIZ62_RS13185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIZ62_RS13205	COG0674	pyruvate-flavodoxin oxidoreductase activity
EIZ62_RS13205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EIZ62_RS13210	COG1013	pyruvate-flavodoxin oxidoreductase activity
EIZ62_RS13240	COG2234	aminopeptidase activity
EIZ62_RS13240	COG4935	Belongs to the peptidase S8 family
EIZ62_RS13250	COG0142	geranyltranstransferase activity
EIZ62_RS13265	COG0179	Fumarylacetoacetate (FAA) hydrolase
EIZ62_RS13280	COG2207	Transcriptional regulator
EIZ62_RS13285	COG1007	ATP synthesis coupled electron transport
EIZ62_RS13295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EIZ62_RS13300	COG0713	ATP synthesis coupled electron transport
EIZ62_RS13305	COG0839	Belongs to the complex I subunit 6 family
EIZ62_RS13310	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIZ62_RS13315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EIZ62_RS13320	COG1034	ATP synthesis coupled electron transport
EIZ62_RS13325	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EIZ62_RS13335	COG0649	NAD binding
EIZ62_RS13340	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIZ62_RS13345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIZ62_RS13380	COG2226	methyltransferase
EIZ62_RS13390	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EIZ62_RS13395	COG1309	transcriptional regulator
EIZ62_RS13415	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EIZ62_RS13420	COG1278	Cold shock
EIZ62_RS13500	COG1309	transcriptional regulator
EIZ62_RS13525	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EIZ62_RS13535	COG0163	prenyltransferase activity
EIZ62_RS13545	COG0109	protoheme IX farnesyltransferase activity
EIZ62_RS13550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EIZ62_RS13585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIZ62_RS13590	COG1333	cytochrome c biogenesis protein
EIZ62_RS13595	COG0785	Cytochrome C biogenesis protein
EIZ62_RS13610	COG0406	alpha-ribazole phosphatase activity
EIZ62_RS13615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EIZ62_RS13635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EIZ62_RS13640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EIZ62_RS13650	COG1846	Transcriptional regulator
EIZ62_RS13660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIZ62_RS13665	COG1116	anion transmembrane transporter activity
EIZ62_RS13680	COG1690	Belongs to the RtcB family
EIZ62_RS13705	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EIZ62_RS13710	COG0018	arginyl-trna synthetase
EIZ62_RS13730	COG0113	porphobilinogen synthase activity
EIZ62_RS13735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EIZ62_RS13735	COG1648	precorrin-2 dehydrogenase activity
EIZ62_RS13740	COG0181	hydroxymethylbilane synthase activity
EIZ62_RS13745	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EIZ62_RS13750	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EIZ62_RS13800	COG0123	including yeast histone deacetylase and acetoin utilization protein
EIZ62_RS13805	COG2223	nitrite transmembrane transporter activity
EIZ62_RS13810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIZ62_RS13830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EIZ62_RS13840	COG0842	Transport permease protein
EIZ62_RS13840	COG1129	ABC transporter
EIZ62_RS13850	COG4991	sh3 domain protein
EIZ62_RS13860	COG0129	dihydroxy-acid dehydratase activity
EIZ62_RS13870	COG1082	Xylose isomerase domain protein TIM barrel
EIZ62_RS13875	COG0248	Ppx GppA phosphatase
EIZ62_RS13895	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EIZ62_RS13910	COG1194	a g-specific adenine glycosylase
EIZ62_RS13915	COG1595	DNA-templated transcription, initiation
EIZ62_RS13925	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS13930	COG2205	protein histidine kinase activity
EIZ62_RS13945	COG0739	heme binding
EIZ62_RS13950	COG2027	D-alanyl-D-alanine carboxypeptidase
EIZ62_RS13970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EIZ62_RS13990	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EIZ62_RS14000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EIZ62_RS14005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EIZ62_RS14020	COG0640	Transcriptional regulator
EIZ62_RS14025	COG2197	response regulator
EIZ62_RS14040	COG0649	NAD binding
EIZ62_RS14050	COG1732	Glycine betaine
EIZ62_RS14055	COG1174	glycine betaine transport
EIZ62_RS14060	COG1174	glycine betaine transport
EIZ62_RS14065	COG1125	glycine betaine transport
EIZ62_RS14065	COG0517	IMP dehydrogenase activity
EIZ62_RS14075	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EIZ62_RS14075	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EIZ62_RS14090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EIZ62_RS14105	COG0667	Aldo Keto reductase
EIZ62_RS14110	COG0302	gtp cyclohydrolase
EIZ62_RS14125	COG0037	tRNA processing
EIZ62_RS14135	COG2027	D-alanyl-D-alanine carboxypeptidase
EIZ62_RS14140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EIZ62_RS14150	COG0586	Pfam SNARE associated Golgi protein
EIZ62_RS14155	COG0789	Transcriptional regulator
EIZ62_RS14165	COG2318	DinB family
EIZ62_RS14170	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS14190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EIZ62_RS14200	COG0254	rRNA binding
EIZ62_RS14205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EIZ62_RS14210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EIZ62_RS14215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EIZ62_RS14240	COG1136	(ABC) transporter
EIZ62_RS14240	COG0577	efflux transmembrane transporter activity
EIZ62_RS14250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIZ62_RS14250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIZ62_RS14295	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS14305	COG0728	peptidoglycan biosynthetic process
EIZ62_RS14315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIZ62_RS14320	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS14350	COG2304	oxidoreductase activity
EIZ62_RS14400	COG1051	belongs to the nudix hydrolase family
EIZ62_RS14495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EIZ62_RS14500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EIZ62_RS14505	COG1754	DNA topoisomerase type I activity
EIZ62_RS14505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EIZ62_RS14515	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EIZ62_RS14525	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EIZ62_RS14530	COG2172	sigma factor antagonist activity
EIZ62_RS14535	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS14540	COG1111	helicase
EIZ62_RS14540	COG1205	dead DEAH box helicase
EIZ62_RS14605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EIZ62_RS14610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EIZ62_RS14620	COG2267	carboxylic ester hydrolase activity
EIZ62_RS14630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIZ62_RS14650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIZ62_RS14660	COG0251	oxidation-reduction process
EIZ62_RS14675	COG0003	Pfam Anion-transporting ATPase
EIZ62_RS14695	COG1610	YqeY-like protein
EIZ62_RS14700	COG1408	metallophosphoesterase
EIZ62_RS14750	COG1595	DNA-templated transcription, initiation
EIZ62_RS14755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EIZ62_RS14780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EIZ62_RS14785	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EIZ62_RS14800	COG1802	Transcriptional regulator
EIZ62_RS14805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EIZ62_RS14810	COG0693	protein deglycase activity
EIZ62_RS14820	COG2890	protein-(glutamine-N5) methyltransferase activity
EIZ62_RS14880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EIZ62_RS14895	COG2124	cytochrome p450
EIZ62_RS14900	COG2197	response regulator
EIZ62_RS14905	COG4585	Histidine kinase
EIZ62_RS14920	COG3844	kynureninase activity
EIZ62_RS14940	COG0191	fructose-bisphosphate aldolase activity
EIZ62_RS14945	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EIZ62_RS14960	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EIZ62_RS14990	COG0542	response to heat
EIZ62_RS15025	COG0789	Transcriptional regulator
EIZ62_RS15030	COG0484	heat shock protein binding
EIZ62_RS15035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EIZ62_RS15040	COG0443	Heat shock 70 kDa protein
EIZ62_RS15050	COG2181	nitrate reductase activity
EIZ62_RS15050	COG0247	lactate metabolic process
EIZ62_RS15065	COG0717	Belongs to the dCTP deaminase family
EIZ62_RS15150	COG1595	DNA-templated transcription, initiation
EIZ62_RS15185	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIZ62_RS15190	COG1595	DNA-templated transcription, initiation
EIZ62_RS15225	COG0137	argininosuccinate synthase activity
EIZ62_RS15280	COG1674	ftsk spoiiie
EIZ62_RS15330	COG1742	UPF0060 membrane protein
EIZ62_RS15345	COG0596	Alpha beta hydrolase
EIZ62_RS15385	COG2815	serine threonine protein kinase
EIZ62_RS15385	COG0515	serine threonine protein kinase
EIZ62_RS15425	COG1957	nucleoside hydrolase
EIZ62_RS15495	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EIZ62_RS15550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIZ62_RS15615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EIZ62_RS15635	COG1741	Belongs to the pirin family
EIZ62_RS15645	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS15655	COG1362	aminopeptidase activity
EIZ62_RS15670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EIZ62_RS15700	COG1733	regulation of RNA biosynthetic process
EIZ62_RS15735	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIZ62_RS15740	COG0022	dehydrogenase e1 component
EIZ62_RS15760	COG0515	serine threonine protein kinase
EIZ62_RS15765	COG0515	serine threonine protein kinase
EIZ62_RS15780	COG1136	(ABC) transporter
EIZ62_RS15780	COG4591	ABC-type transport system involved in lipoprotein release permease component
EIZ62_RS15800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EIZ62_RS15810	COG0746	molybdenum cofactor guanylyltransferase activity
EIZ62_RS15830	COG1522	sequence-specific DNA binding
EIZ62_RS15835	COG1309	transcriptional regulator
EIZ62_RS15840	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIZ62_RS15865	COG3396	Phenylacetate-CoA oxygenase
EIZ62_RS15870	COG3460	Phenylacetate-CoA oxygenase
EIZ62_RS15875	COG3396	Phenylacetate-CoA oxygenase
EIZ62_RS15880	COG2151	metal-sulfur cluster biosynthetic enzyme
EIZ62_RS15885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIZ62_RS15895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIZ62_RS15925	COG1716	ATPase activity
EIZ62_RS15930	COG1716	ATPase activity
EIZ62_RS15945	COG0768	penicillin binding
EIZ62_RS15950	COG0515	serine threonine protein kinase
EIZ62_RS15955	COG3764	Sortase (surface protein transpeptidase)
EIZ62_RS15960	COG3764	Sortase (surface protein transpeptidase)
EIZ62_RS15970	COG3764	Sortase (surface protein transpeptidase)
EIZ62_RS15985	COG0457	Tetratricopeptide repeat
EIZ62_RS15985	COG0705	Rhomboid family
EIZ62_RS16025	COG0515	serine threonine protein kinase
EIZ62_RS16050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EIZ62_RS16060	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EIZ62_RS16065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EIZ62_RS16070	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EIZ62_RS16075	COG0592	DNA-directed DNA polymerase activity
EIZ62_RS16090	COG0594	ribonuclease P activity
EIZ62_RS16095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EIZ62_RS16100	COG0706	membrane insertase activity
EIZ62_RS16110	COG0357	Ribosomal RNA small subunit methyltransferase G
EIZ62_RS16115	COG1192	Involved in chromosome partitioning
EIZ62_RS16130	COG3118	belongs to the thioredoxin family
EIZ62_RS16135	COG0492	ferredoxin-NADP+ reductase activity
EIZ62_RS16145	COG1595	DNA-templated transcription, initiation
EIZ62_RS16150	COG2815	serine threonine protein kinase
EIZ62_RS16150	COG0515	serine threonine protein kinase
EIZ62_RS16165	COG0617	tRNA 3'-terminal CCA addition
EIZ62_RS16185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIZ62_RS16210	COG0360	Binds together with S18 to 16S ribosomal RNA
EIZ62_RS16215	COG0629	single-stranded DNA binding
EIZ62_RS16220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EIZ62_RS16225	COG0359	binds to the 23S rRNA
EIZ62_RS16235	COG0305	Participates in initiation and elongation during chromosome replication
EIZ62_RS16265	COG2814	Major facilitator Superfamily
EIZ62_RS16290	COG0626	cystathionine gamma-synthase activity
EIZ62_RS16295	COG1950	PFAM Membrane protein of
EIZ62_RS16300	COG0662	Cupin 2, conserved barrel domain protein
EIZ62_RS16325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EIZ62_RS16340	COG1609	Transcriptional regulator
EIZ62_RS16345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIZ62_RS16355	COG1271	oxidase subunit
EIZ62_RS16360	COG1294	oxidase, subunit
EIZ62_RS16365	COG4988	ABC transporter
EIZ62_RS16375	COG0739	heme binding
EIZ62_RS16380	COG0561	phosphatase activity
EIZ62_RS16390	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EIZ62_RS16395	COG0789	Transcriptional regulator
EIZ62_RS16410	COG1131	(ABC) transporter
EIZ62_RS16420	COG1131	(ABC) transporter
EIZ62_RS16435	COG2807	transmembrane transport
EIZ62_RS16440	COG2186	Transcriptional regulator
EIZ62_RS16450	COG0561	phosphatase activity
EIZ62_RS16455	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EIZ62_RS16465	COG2837	iron assimilation
EIZ62_RS16470	COG2372	response to copper ion
EIZ62_RS16480	COG1999	signal sequence binding
EIZ62_RS16500	COG0006	proline dipeptidase activity
EIZ62_RS16520	COG0653	protein targeting
EIZ62_RS16535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIZ62_RS16625	COG1595	DNA-templated transcription, initiation
EIZ62_RS16630	COG0318	PFAM AMP-dependent synthetase and ligase
EIZ62_RS16665	COG2329	Antibiotic biosynthesis monooxygenase
EIZ62_RS16675	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS16680	COG0477	Major facilitator Superfamily
EIZ62_RS16695	COG0477	Major facilitator Superfamily
EIZ62_RS16715	COG1191	sigma factor activity
EIZ62_RS16720	COG1191	sigma factor activity
EIZ62_RS16760	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EIZ62_RS16785	COG4941	Belongs to the sigma-70 factor family
EIZ62_RS16845	COG0151	Belongs to the GarS family
EIZ62_RS16860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EIZ62_RS16870	COG2197	response regulator
EIZ62_RS16905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EIZ62_RS16910	COG0047	phosphoribosylformylglycinamidine synthase activity
EIZ62_RS16915	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EIZ62_RS16950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EIZ62_RS16985	COG1643	Atp-dependent helicase
EIZ62_RS16995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EIZ62_RS16995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EIZ62_RS17000	COG0785	Cytochrome C biogenesis protein
EIZ62_RS17020	COG2188	Transcriptional regulator
EIZ62_RS17125	COG0513	Belongs to the DEAD box helicase family
EIZ62_RS17160	COG0739	heme binding
EIZ62_RS17160	COG0741	lytic transglycosylase activity
EIZ62_RS17160	COG1196	nuclear chromosome segregation
EIZ62_RS17170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EIZ62_RS17175	COG0579	oxidoreductase
EIZ62_RS17200	COG1252	NADH dehydrogenase
EIZ62_RS17215	COG1846	Transcriptional regulator
EIZ62_RS17240	COG2197	response regulator
EIZ62_RS17245	COG4585	Histidine kinase
EIZ62_RS17255	COG1131	(ABC) transporter
EIZ62_RS17295	COG1309	transcriptional regulator
EIZ62_RS17310	COG1196	nuclear chromosome segregation
EIZ62_RS17310	COG0741	lytic transglycosylase activity
EIZ62_RS17310	COG0739	heme binding
EIZ62_RS17315	COG0671	phosphoesterase, PA-phosphatase related
EIZ62_RS17335	COG1937	Protein conserved in bacteria
EIZ62_RS17345	COG0306	phosphate transporter
EIZ62_RS17365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EIZ62_RS17370	COG0494	nUDIX hydrolase
EIZ62_RS17370	COG0406	alpha-ribazole phosphatase activity
EIZ62_RS17375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EIZ62_RS17385	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EIZ62_RS17390	COG1725	Transcriptional regulator
EIZ62_RS17395	COG0456	acetyltransferase
EIZ62_RS17400	COG0737	Belongs to the 5'-nucleotidase family
EIZ62_RS17410	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS17415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIZ62_RS17420	COG1609	Transcriptional regulator
EIZ62_RS17425	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS17450	COG2897	thiosulfate sulfurtransferase activity
EIZ62_RS17475	COG3485	protocatechuate 3,4-dioxygenase
EIZ62_RS17480	COG0735	belongs to the Fur family
EIZ62_RS17490	COG1490	D-aminoacyl-tRNA deacylase activity
EIZ62_RS17505	COG4552	Acetyltransferase involved in intracellular survival and related
EIZ62_RS17530	COG0604	alcohol dehydrogenase
EIZ62_RS17595	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS17610	COG0588	phosphoglycerate mutase activity
EIZ62_RS17625	COG5002	protein histidine kinase activity
EIZ62_RS17645	COG1329	Transcriptional regulator
EIZ62_RS17650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EIZ62_RS17655	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EIZ62_RS17660	COG0215	cysteine-tRNA ligase activity
EIZ62_RS17665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIZ62_RS17675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EIZ62_RS17685	COG3842	ATPase activity
EIZ62_RS17695	COG0582	viral genome integration into host DNA
EIZ62_RS17745	COG2188	Transcriptional regulator
EIZ62_RS17760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIZ62_RS17795	COG2197	response regulator
EIZ62_RS17825	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EIZ62_RS17850	COG1105	Belongs to the carbohydrate kinase PfkB family
EIZ62_RS17865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EIZ62_RS17900	COG0463	Glycosyl transferase, family 2
EIZ62_RS17920	COG0459	protein refolding
EIZ62_RS17930	COG1215	transferase activity, transferring glycosyl groups
EIZ62_RS17985	COG1136	(ABC) transporter
EIZ62_RS17985	COG0577	efflux transmembrane transporter activity
EIZ62_RS17990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIZ62_RS17990	COG1263	PTS System
EIZ62_RS17995	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EIZ62_RS18000	COG1737	Transcriptional regulator
EIZ62_RS18015	COG2814	Major facilitator Superfamily
EIZ62_RS18035	COG3973	AAA domain
EIZ62_RS18040	COG1061	Type III restriction enzyme res subunit
EIZ62_RS18070	COG1278	Cold shock
EIZ62_RS18075	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EIZ62_RS18080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EIZ62_RS18090	COG2814	Major facilitator Superfamily
EIZ62_RS18105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EIZ62_RS18115	COG2252	PERMEase
EIZ62_RS18145	COG0667	Aldo Keto reductase
EIZ62_RS18170	COG3629	intracellular signal transduction
EIZ62_RS18170	COG3903	Transcriptional regulator
EIZ62_RS18235	COG0583	DNA-binding transcription factor activity
EIZ62_RS18285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EIZ62_RS18320	COG0277	FAD linked oxidase domain protein
EIZ62_RS18325	COG5006	permease, DMT superfamily
EIZ62_RS18340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIZ62_RS18355	COG0318	PFAM AMP-dependent synthetase and ligase
EIZ62_RS18375	COG0259	pyridoxamine-phosphate oxidase activity
EIZ62_RS18390	COG0577	efflux transmembrane transporter activity
EIZ62_RS18390	COG1136	(ABC) transporter
EIZ62_RS18395	COG0577	efflux transmembrane transporter activity
EIZ62_RS18395	COG1136	(ABC) transporter
EIZ62_RS18410	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS18415	COG2205	protein histidine kinase activity
EIZ62_RS18420	COG4821	SIS domain
EIZ62_RS18495	COG1021	2,3-dihydroxybenzoate-AMP ligase
EIZ62_RS18505	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS18510	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS18530	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS18575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EIZ62_RS18580	COG1024	Enoyl-CoA hydratase
EIZ62_RS18635	COG1309	transcriptional regulator
EIZ62_RS18650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIZ62_RS18680	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS18690	COG1309	transcriptional regulator
EIZ62_RS18700	COG0515	serine threonine protein kinase
EIZ62_RS18700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EIZ62_RS18715	COG1024	Enoyl-CoA hydratase
EIZ62_RS18730	COG0318	PFAM AMP-dependent synthetase and ligase
EIZ62_RS18805	COG0531	amino acid
EIZ62_RS18835	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EIZ62_RS18870	COG1686	Belongs to the peptidase S11 family
EIZ62_RS18915	COG0477	Major facilitator Superfamily
EIZ62_RS18960	COG0702	epimerase
EIZ62_RS18975	COG1309	transcriptional regulator
EIZ62_RS18990	COG4770	biotin carboxylase activity
EIZ62_RS19000	COG3629	intracellular signal transduction
EIZ62_RS19000	COG3903	Transcriptional regulator
EIZ62_RS19030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EIZ62_RS19050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIZ62_RS19060	COG3321	synthase
EIZ62_RS19060	COG3321	synthase
EIZ62_RS19060	COG0604	alcohol dehydrogenase
EIZ62_RS19060	COG0604	alcohol dehydrogenase
EIZ62_RS19065	COG0604	alcohol dehydrogenase
EIZ62_RS19065	COG3321	synthase
EIZ62_RS19070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EIZ62_RS19090	COG1309	transcriptional regulator
EIZ62_RS19095	COG0318	PFAM AMP-dependent synthetase and ligase
EIZ62_RS19115	COG0583	DNA-binding transcription factor activity
EIZ62_RS19125	COG2855	membrane
EIZ62_RS19130	COG1846	Transcriptional regulator
EIZ62_RS19135	COG3384	dioxygenase
EIZ62_RS19150	COG0477	Major facilitator Superfamily
EIZ62_RS19185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EIZ62_RS19215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EIZ62_RS19220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EIZ62_RS19230	COG0315	cyclic pyranopterin monophosphate synthase activity
EIZ62_RS19235	COG0315	cyclic pyranopterin monophosphate synthase activity
EIZ62_RS19235	COG0521	Mo-molybdopterin cofactor biosynthetic process
EIZ62_RS19270	COG0708	Exodeoxyribonuclease III
EIZ62_RS19285	COG2072	flavoprotein involved in K transport
EIZ62_RS19290	COG2267	carboxylic ester hydrolase activity
EIZ62_RS19295	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS19305	COG4946	Tricorn protease homolog
EIZ62_RS19305	COG0793	Belongs to the peptidase S41A family
EIZ62_RS19315	COG2409	Drug exporters of the RND superfamily
EIZ62_RS19325	COG0310	cobalt ion transport
EIZ62_RS19335	COG1122	ATPase activity
EIZ62_RS19340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIZ62_RS19360	COG0442	prolyl-tRNA aminoacylation
EIZ62_RS19370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIZ62_RS19395	COG0084	hydrolase, TatD family'
EIZ62_RS19400	COG1388	LysM domain
EIZ62_RS19405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EIZ62_RS19410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EIZ62_RS19430	COG0488	(ABC) transporter
EIZ62_RS19455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EIZ62_RS19470	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EIZ62_RS19475	COG2197	response regulator
EIZ62_RS19480	COG1846	Transcriptional regulator
EIZ62_RS19485	COG4106	trans-aconitate 2-methyltransferase activity
EIZ62_RS19500	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EIZ62_RS19510	COG0193	aminoacyl-tRNA hydrolase activity
EIZ62_RS19515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EIZ62_RS19520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EIZ62_RS19525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EIZ62_RS19540	COG4585	Histidine kinase
EIZ62_RS19570	COG0477	Major facilitator Superfamily
EIZ62_RS19675	COG0148	phosphopyruvate hydratase activity
EIZ62_RS19695	COG1252	NADH dehydrogenase
EIZ62_RS19700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EIZ62_RS19705	COG0577	efflux transmembrane transporter activity
EIZ62_RS19705	COG1136	(ABC) transporter
EIZ62_RS19710	COG0577	efflux transmembrane transporter activity
EIZ62_RS19710	COG1136	(ABC) transporter
EIZ62_RS19740	COG0183	Belongs to the thiolase family
EIZ62_RS19745	COG2755	lipolytic protein G-D-S-L family
EIZ62_RS19775	COG1309	transcriptional regulator
EIZ62_RS19805	COG0019	diaminopimelate decarboxylase activity
EIZ62_RS19810	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EIZ62_RS19825	COG1228	amidohydrolase
EIZ62_RS19845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIZ62_RS19850	COG0488	(ABC) transporter
EIZ62_RS19855	COG1794	racemase activity, acting on amino acids and derivatives
EIZ62_RS19860	COG1191	sigma factor activity
EIZ62_RS19865	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS19890	COG3104	oligopeptide transport
EIZ62_RS19895	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS19900	COG2205	protein histidine kinase activity
EIZ62_RS19935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EIZ62_RS19975	COG1316	TRANSCRIPTIONal
EIZ62_RS19980	COG1607	acyl-coa hydrolase
EIZ62_RS20000	COG1316	TRANSCRIPTIONal
EIZ62_RS20005	COG1316	TRANSCRIPTIONal
EIZ62_RS20030	COG0778	Nitroreductase
EIZ62_RS20030	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EIZ62_RS20035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EIZ62_RS20075	COG2835	tetraacyldisaccharide 4'-kinase activity
EIZ62_RS20085	COG1482	cell wall glycoprotein biosynthetic process
EIZ62_RS20095	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EIZ62_RS20135	COG0714	Associated with various cellular activities
EIZ62_RS20155	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EIZ62_RS20160	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS20165	COG5002	protein histidine kinase activity
EIZ62_RS20170	COG0823	Involved in the tonB-independent uptake of proteins
EIZ62_RS20180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EIZ62_RS20185	COG2197	response regulator
EIZ62_RS20190	COG3214	Protein conserved in bacteria
EIZ62_RS20200	COG0653	protein targeting
EIZ62_RS20235	COG1134	teichoic acid transport
EIZ62_RS20245	COG1309	transcriptional regulator
EIZ62_RS20305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EIZ62_RS20310	COG1216	Glycosyl transferase, family 2
EIZ62_RS20315	COG1216	Glycosyl transferase, family 2
EIZ62_RS20320	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS20325	COG1175	transmembrane transport
EIZ62_RS20330	COG1653	transport
EIZ62_RS20340	COG0515	serine threonine protein kinase
EIZ62_RS20345	COG0515	serine threonine protein kinase
EIZ62_RS20350	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EIZ62_RS20365	COG2884	Cell division ATP-binding protein ftsE
EIZ62_RS20375	COG0793	Belongs to the peptidase S41A family
EIZ62_RS20380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EIZ62_RS20400	COG0583	DNA-binding transcription factor activity
EIZ62_RS20420	COG2223	nitrite transmembrane transporter activity
EIZ62_RS20445	COG3973	AAA domain
EIZ62_RS20455	COG0776	regulation of translation
EIZ62_RS20460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EIZ62_RS20465	COG1678	Uncharacterized ACR, COG1678
EIZ62_RS20485	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS20490	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EIZ62_RS20515	COG3654	unkown
EIZ62_RS20550	COG1174	glycine betaine transport
EIZ62_RS20555	COG0517	IMP dehydrogenase activity
EIZ62_RS20555	COG1125	glycine betaine transport
EIZ62_RS20560	COG1174	glycine betaine transport
EIZ62_RS20570	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EIZ62_RS20600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EIZ62_RS20615	COG0277	FAD linked oxidase domain protein
EIZ62_RS20660	COG1335	isochorismatase
EIZ62_RS20670	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EIZ62_RS20680	COG1113	amino acid transport
EIZ62_RS20705	COG1234	tRNA 3'-trailer cleavage
EIZ62_RS20710	COG1263	PTS System
EIZ62_RS20715	COG1263	PTS System
EIZ62_RS20720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIZ62_RS20725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EIZ62_RS20735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EIZ62_RS20755	COG0477	Major facilitator Superfamily
EIZ62_RS20780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIZ62_RS20795	COG4555	ABC transporter
EIZ62_RS20800	COG4758	membrane
EIZ62_RS20805	COG2733	membrane
EIZ62_RS20865	COG3764	Sortase (surface protein transpeptidase)
EIZ62_RS20875	COG0706	membrane insertase activity
EIZ62_RS20880	COG0179	Fumarylacetoacetate (FAA) hydrolase
EIZ62_RS20885	COG0151	Belongs to the GarS family
EIZ62_RS20935	COG2814	Major facilitator Superfamily
EIZ62_RS20960	COG0506	proline dehydrogenase activity
EIZ62_RS20980	COG4702	Belongs to the UPF0303 family
EIZ62_RS20985	COG0673	inositol 2-dehydrogenase activity
EIZ62_RS20990	COG1940	carbohydrate kinase activity
EIZ62_RS21000	COG2188	Transcriptional regulator
EIZ62_RS21005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIZ62_RS21080	COG3397	chitin binding
EIZ62_RS21090	COG2197	response regulator
EIZ62_RS21105	COG1126	abc transporter atp-binding protein
EIZ62_RS21110	COG0765	amino acid transport
EIZ62_RS21115	COG0765	amino acid transport
EIZ62_RS21120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIZ62_RS21130	COG0154	amidase activity
EIZ62_RS21135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EIZ62_RS21150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIZ62_RS21160	COG0583	DNA-binding transcription factor activity
EIZ62_RS21205	COG0406	alpha-ribazole phosphatase activity
EIZ62_RS21230	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS21245	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS21280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EIZ62_RS21300	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EIZ62_RS21305	COG4977	sequence-specific DNA binding
EIZ62_RS21315	COG0589	response to stress
EIZ62_RS21325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EIZ62_RS21355	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EIZ62_RS21375	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS21390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIZ62_RS21395	COG1309	transcriptional regulator
EIZ62_RS21410	COG1487	ribonuclease activity
EIZ62_RS21420	COG1946	Acyl-CoA thioesterase
EIZ62_RS21455	COG0028	Belongs to the TPP enzyme family
EIZ62_RS21490	COG1472	Belongs to the glycosyl hydrolase 3 family
EIZ62_RS21500	COG1609	Transcriptional regulator
EIZ62_RS21505	COG0673	inositol 2-dehydrogenase activity
EIZ62_RS21525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EIZ62_RS21540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EIZ62_RS21565	COG3718	enzyme involved in inositol metabolism
EIZ62_RS21570	COG3962	Belongs to the TPP enzyme family
EIZ62_RS21595	COG1131	(ABC) transporter
EIZ62_RS21630	COG0702	epimerase
EIZ62_RS21635	COG1733	regulation of RNA biosynthetic process
EIZ62_RS21655	COG0629	single-stranded DNA binding
EIZ62_RS21685	COG1136	(ABC) transporter
EIZ62_RS21700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EIZ62_RS21730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIZ62_RS21745	COG1486	melibiose metabolic process
EIZ62_RS21755	COG0668	transmembrane transport
EIZ62_RS21765	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EIZ62_RS21765	COG3291	Pkd domain containing protein
EIZ62_RS21800	COG4266	Belongs to the allantoicase family
EIZ62_RS21805	COG2226	methyltransferase
EIZ62_RS21810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIZ62_RS21855	COG0494	nUDIX hydrolase
EIZ62_RS21875	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EIZ62_RS21880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EIZ62_RS21885	COG0584	glycerophosphoryl diester phosphodiesterase
EIZ62_RS21890	COG1113	amino acid transport
EIZ62_RS21895	COG1113	amino acid transport
EIZ62_RS21905	COG1113	amino acid transport
EIZ62_RS21920	COG4552	Acetyltransferase involved in intracellular survival and related
EIZ62_RS21935	COG3594	Acyltransferase
EIZ62_RS21960	COG0544	peptidyl-prolyl cis-trans isomerase activity
EIZ62_RS21965	COG0740	serine-type endopeptidase activity
EIZ62_RS21970	COG0740	serine-type endopeptidase activity
EIZ62_RS21975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EIZ62_RS21985	COG0525	valine-tRNA ligase activity
EIZ62_RS21990	COG0285	dihydrofolate synthase activity
EIZ62_RS22000	COG0105	UTP biosynthetic process
EIZ62_RS22005	COG1077	Cell shape determining protein MreB Mrl
EIZ62_RS22020	COG0768	penicillin binding
EIZ62_RS22025	COG0772	Belongs to the SEDS family
EIZ62_RS22050	COG1530	ribonuclease E activity
EIZ62_RS22055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EIZ62_RS22060	COG0673	inositol 2-dehydrogenase activity
EIZ62_RS22110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EIZ62_RS22115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EIZ62_RS22120	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EIZ62_RS22125	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS22145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EIZ62_RS22155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EIZ62_RS22170	COG0501	Belongs to the peptidase M48B family
EIZ62_RS22175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EIZ62_RS22185	COG0799	negative regulation of ribosome biogenesis
EIZ62_RS22190	COG0588	phosphoglycerate mutase activity
EIZ62_RS22225	COG0495	leucyl-tRNA aminoacylation
EIZ62_RS22235	COG1307	EDD domain protein, DegV family
EIZ62_RS22240	COG1596	polysaccharide export
EIZ62_RS22240	COG1555	photosystem II stabilization
EIZ62_RS22260	COG0268	Binds directly to 16S ribosomal RNA
EIZ62_RS22265	COG0481	GTPase activity
EIZ62_RS22295	COG1420	regulation of RNA biosynthetic process
EIZ62_RS22300	COG0484	heat shock protein binding
EIZ62_RS22315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIZ62_RS22325	COG0537	adenosine 5'-monophosphoramidase activity
EIZ62_RS22330	COG1234	tRNA 3'-trailer cleavage
EIZ62_RS22335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EIZ62_RS22345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIZ62_RS22355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EIZ62_RS22395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EIZ62_RS22410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EIZ62_RS22420	COG0768	penicillin binding
EIZ62_RS22475	COG1381	Involved in DNA repair and RecF pathway recombination
EIZ62_RS22480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EIZ62_RS22495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EIZ62_RS22505	COG3443	Belongs to the bacterial solute-binding protein 9 family
EIZ62_RS22505	COG0803	Belongs to the bacterial solute-binding protein 9 family
EIZ62_RS22510	COG0423	glycine-tRNA ligase activity
EIZ62_RS22530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EIZ62_RS22530	COG0574	Belongs to the PEP-utilizing enzyme family
EIZ62_RS22550	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS22555	COG1309	transcriptional regulator
EIZ62_RS22560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EIZ62_RS22560	COG2146	nitrite reductase [NAD(P)H] activity
EIZ62_RS22565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EIZ62_RS22565	COG2146	nitrite reductase [NAD(P)H] activity
EIZ62_RS22570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EIZ62_RS22610	COG0243	molybdopterin cofactor binding
EIZ62_RS22615	COG2949	membrane
EIZ62_RS22635	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EIZ62_RS22645	COG0358	DNA primase activity
EIZ62_RS22665	COG1070	Carbohydrate kinase
EIZ62_RS22705	COG1764	response to oxidative stress
EIZ62_RS22710	COG1846	Transcriptional regulator
EIZ62_RS22715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EIZ62_RS22715	COG0825	malonyl-CoA metabolic process
EIZ62_RS22720	COG0318	PFAM AMP-dependent synthetase and ligase
EIZ62_RS22730	COG1077	Cell shape determining protein MreB Mrl
EIZ62_RS22750	COG2130	NADP-dependent
EIZ62_RS22755	COG1764	response to oxidative stress
EIZ62_RS22770	COG1280	lysine exporter protein (LysE YggA)
EIZ62_RS22785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EIZ62_RS22825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIZ62_RS22830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EIZ62_RS22835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIZ62_RS22850	COG1741	Belongs to the pirin family
EIZ62_RS22875	COG0513	Belongs to the DEAD box helicase family
EIZ62_RS22880	COG1278	Cold shock
EIZ62_RS22895	COG0789	Transcriptional regulator
EIZ62_RS22900	COG0667	Aldo Keto reductase
EIZ62_RS22915	COG2197	response regulator
EIZ62_RS22920	COG4585	Histidine kinase
EIZ62_RS22935	COG1309	transcriptional regulator
EIZ62_RS22940	COG0477	Major facilitator Superfamily
EIZ62_RS22955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIZ62_RS22960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EIZ62_RS23005	COG1358	cellular component organization or biogenesis
EIZ62_RS23015	COG0586	Pfam SNARE associated Golgi protein
EIZ62_RS23100	COG0546	phosphoglycolate phosphatase activity
EIZ62_RS23115	COG1846	Transcriptional regulator
EIZ62_RS23120	COG0778	Nitroreductase
EIZ62_RS23160	COG2259	Doxx family
EIZ62_RS23220	COG4122	O-methyltransferase activity
EIZ62_RS23225	COG2124	cytochrome p450
EIZ62_RS23230	COG0183	Belongs to the thiolase family
EIZ62_RS23240	COG3845	ABC transporter
EIZ62_RS23255	COG1657	PFAM Prenyltransferase squalene oxidase
EIZ62_RS23285	COG1309	transcriptional regulator
EIZ62_RS23290	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS23315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIZ62_RS23325	COG0860	N-Acetylmuramoyl-L-alanine amidase
EIZ62_RS23345	COG2030	dehydratase
EIZ62_RS23365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EIZ62_RS23385	COG0800	Aldolase
EIZ62_RS23390	COG3022	response to hydroperoxide
EIZ62_RS23395	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EIZ62_RS23490	COG1201	RNA secondary structure unwinding
EIZ62_RS23520	COG3540	Alkaline phosphatase
EIZ62_RS23525	COG2814	Major facilitator Superfamily
EIZ62_RS23540	COG1834	amidinotransferase
EIZ62_RS23560	COG0384	phenazine biosynthesis protein PhzF
EIZ62_RS23600	COG1994	Peptidase M50
EIZ62_RS23625	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EIZ62_RS23635	COG2814	Major facilitator Superfamily
EIZ62_RS23640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EIZ62_RS23640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EIZ62_RS23675	COG0174	glutamine synthetase
EIZ62_RS23685	COG0477	Major facilitator Superfamily
EIZ62_RS23705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIZ62_RS23720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EIZ62_RS23735	COG1609	Transcriptional regulator
EIZ62_RS23745	COG2182	Extracellular solute-binding protein
EIZ62_RS23750	COG1175	transmembrane transport
EIZ62_RS23755	COG3833	ABC-type maltose transport systems, permease component
EIZ62_RS23760	COG0366	Alpha amylase catalytic
EIZ62_RS23840	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS23880	COG1733	regulation of RNA biosynthetic process
EIZ62_RS23895	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EIZ62_RS23895	COG1672	PFAM Archaeal ATPase
EIZ62_RS23925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EIZ62_RS23930	COG0321	lipoyl(octanoyl) transferase activity
EIZ62_RS23960	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS23970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EIZ62_RS23980	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIZ62_RS23985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIZ62_RS23990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EIZ62_RS24020	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EIZ62_RS24035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EIZ62_RS24035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EIZ62_RS24040	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EIZ62_RS24055	COG1132	(ABC) transporter
EIZ62_RS24060	COG4106	trans-aconitate 2-methyltransferase activity
EIZ62_RS24080	COG4585	Histidine kinase
EIZ62_RS24085	COG2197	response regulator
EIZ62_RS24090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EIZ62_RS24095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EIZ62_RS24115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIZ62_RS24120	COG1104	cysteine desulfurase activity
EIZ62_RS24125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EIZ62_RS24130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EIZ62_RS24140	COG1376	ErfK ybiS ycfS ynhG family protein
EIZ62_RS24150	COG1845	cytochrome c oxidase, subunit III
EIZ62_RS24155	COG2010	Cytochrome c
EIZ62_RS24160	COG0723	plastoquinol--plastocyanin reductase activity
EIZ62_RS24165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EIZ62_RS24170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIZ62_RS24175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EIZ62_RS24190	COG0745	RESPONSE REGULATOR receiver
EIZ62_RS24195	COG2205	protein histidine kinase activity
EIZ62_RS24270	COG0003	Pfam Anion-transporting ATPase
EIZ62_RS24280	COG1940	carbohydrate kinase activity
EIZ62_RS24305	COG4585	Histidine kinase
EIZ62_RS24315	COG0205	6-phosphofructokinase activity
EIZ62_RS24330	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EIZ62_RS24340	COG2193	ferroxidase activity
EIZ62_RS24345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EIZ62_RS24355	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EIZ62_RS24360	COG2815	serine threonine protein kinase
EIZ62_RS24360	COG0515	serine threonine protein kinase
EIZ62_RS24365	COG2022	thiamine diphosphate biosynthetic process
EIZ62_RS24375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIZ62_RS24375	COG2022	thiamine diphosphate biosynthetic process
EIZ62_RS24395	COG0352	thiamine-phosphate diphosphorylase activity
EIZ62_RS24415	COG1309	transcriptional regulator
EIZ62_RS24425	COG3842	ATPase activity
EIZ62_RS24435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EIZ62_RS24465	COG0275	rRNA processing
EIZ62_RS24475	COG0768	penicillin binding
EIZ62_RS24480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EIZ62_RS24490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EIZ62_RS24495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EIZ62_RS24505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EIZ62_RS24510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EIZ62_RS24525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EIZ62_RS24530	COG1799	cell septum assembly
EIZ62_RS24545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EIZ62_RS24555	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EIZ62_RS24605	COG0587	DNA-directed DNA polymerase activity
EIZ62_RS24610	COG1432	Conserved Protein
EIZ62_RS24630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EIZ62_RS24650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EIZ62_RS24655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIZ62_RS24660	COG0131	Imidazoleglycerol-phosphate dehydratase
EIZ62_RS24665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EIZ62_RS24670	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EIZ62_RS24675	COG0251	oxidation-reduction process
EIZ62_RS24680	COG0107	imidazoleglycerol-phosphate synthase activity
EIZ62_RS24690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EIZ62_RS24715	COG0134	indole-3-glycerol-phosphate synthase activity
EIZ62_RS24725	COG0133	tryptophan synthase activity
EIZ62_RS24730	COG0159	tryptophan synthase activity
EIZ62_RS24740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EIZ62_RS24750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EIZ62_RS24755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIZ62_RS24785	COG0069	glutamate synthase activity
EIZ62_RS24785	COG0067	glutamate synthase
EIZ62_RS24785	COG0070	glutamate synthase
EIZ62_RS24800	COG2304	oxidoreductase activity
EIZ62_RS24820	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS24830	COG1309	transcriptional regulator
EIZ62_RS24835	COG0183	Belongs to the thiolase family
EIZ62_RS24840	COG1278	Cold shock
EIZ62_RS24865	COG1024	Enoyl-CoA hydratase
EIZ62_RS24875	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS24905	COG0287	Prephenate dehydrogenase
EIZ62_RS24905	COG1605	Chorismate mutase
EIZ62_RS24925	COG0737	Belongs to the 5'-nucleotidase family
EIZ62_RS24975	COG2936	dipeptidyl-peptidase activity
EIZ62_RS24980	COG2050	protein possibly involved in aromatic compounds catabolism
EIZ62_RS25020	COG2226	methyltransferase
EIZ62_RS25025	COG0539	negative regulation of cytoplasmic translation
EIZ62_RS25035	COG0237	dephospho-CoA kinase activity
EIZ62_RS25050	COG1309	transcriptional regulator
EIZ62_RS25060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EIZ62_RS25075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EIZ62_RS25100	COG0436	Aminotransferase
EIZ62_RS25105	COG1733	regulation of RNA biosynthetic process
EIZ62_RS25110	COG0789	Transcriptional regulator
EIZ62_RS25130	COG2313	pseudouridylate synthase activity
EIZ62_RS25140	COG0477	Major facilitator Superfamily
EIZ62_RS25145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EIZ62_RS25155	COG0556	nucleotide-excision repair
EIZ62_RS25175	COG0477	Major facilitator Superfamily
EIZ62_RS25190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EIZ62_RS25220	COG0322	excinuclease ABC activity
EIZ62_RS25225	COG1660	Displays ATPase and GTPase activities
EIZ62_RS25230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EIZ62_RS25235	COG1481	regulation of sporulation
EIZ62_RS25245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EIZ62_RS25250	COG0126	phosphoglycerate kinase activity
EIZ62_RS25255	COG0149	triose-phosphate isomerase activity
EIZ62_RS25260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EIZ62_RS25270	COG0166	Belongs to the GPI family
EIZ62_RS25285	COG0363	glucosamine-6-phosphate deaminase activity
EIZ62_RS25300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EIZ62_RS25310	COG0109	protoheme IX farnesyltransferase activity
EIZ62_RS25325	COG1612	heme a metabolic process
EIZ62_RS25335	COG1131	(ABC) transporter
EIZ62_RS25350	COG0719	Fe-S assembly protein
EIZ62_RS25360	COG0396	ATPase activity
EIZ62_RS25365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EIZ62_RS25370	COG0822	iron-sulfur transferase activity
EIZ62_RS25385	COG2076	Multidrug Resistance protein
EIZ62_RS25390	COG3226	Transcriptional regulator
EIZ62_RS25405	COG2171	N-acyltransferase activity
EIZ62_RS25470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIZ62_RS25480	COG2272	Belongs to the type-B carboxylesterase lipase family
EIZ62_RS25495	COG0768	penicillin binding
EIZ62_RS25500	COG2197	response regulator
EIZ62_RS25505	COG4585	Histidine kinase
EIZ62_RS25535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EIZ62_RS25555	COG5285	phytanoyl-CoA dioxygenase
EIZ62_RS25585	COG2249	NAD(P)H dehydrogenase (quinone) activity
EIZ62_RS25590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EIZ62_RS25625	COG1797	cobyrinic acid a,c-diamide synthase activity
EIZ62_RS25630	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EIZ62_RS25640	COG1492	cobalamin metabolic process
EIZ62_RS25645	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EIZ62_RS25660	COG0235	Class ii aldolase
EIZ62_RS25680	COG0488	(ABC) transporter
EIZ62_RS25730	COG3387	PFAM Glycoside hydrolase 15-related
EIZ62_RS25745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EIZ62_RS25750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EIZ62_RS25765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EIZ62_RS25770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EIZ62_RS25790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EIZ62_RS25805	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS25810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EIZ62_RS25820	COG2186	Transcriptional regulator
EIZ62_RS25840	COG3830	Belongs to the UPF0237 family
EIZ62_RS25840	COG0560	Phosphoserine phosphatase
EIZ62_RS25845	COG1131	(ABC) transporter
EIZ62_RS25845	COG0842	Transport permease protein
EIZ62_RS25845	COG1716	ATPase activity
EIZ62_RS25855	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EIZ62_RS25860	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS25865	COG4585	Histidine kinase
EIZ62_RS25870	COG2197	response regulator
EIZ62_RS25885	COG1119	ATPase activity
EIZ62_RS25910	COG1881	PFAM PEBP family protein
EIZ62_RS25920	COG2094	Belongs to the DNA glycosylase MPG family
EIZ62_RS25950	COG0647	UMP catabolic process
EIZ62_RS25955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EIZ62_RS25960	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EIZ62_RS25965	COG1120	ATPase activity
EIZ62_RS25985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EIZ62_RS25990	COG0497	DNA recombination
EIZ62_RS26010	COG3387	PFAM Glycoside hydrolase 15-related
EIZ62_RS26015	COG0504	CTP synthase activity
EIZ62_RS26020	COG0494	nUDIX hydrolase
EIZ62_RS26030	COG0686	Belongs to the AlaDH PNT family
EIZ62_RS26045	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EIZ62_RS26050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EIZ62_RS26055	COG1187	pseudouridine synthase activity
EIZ62_RS26075	COG0723	plastoquinol--plastocyanin reductase activity
EIZ62_RS26095	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EIZ62_RS26105	COG1160	GTP binding
EIZ62_RS26150	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS26170	COG0671	phosphoesterase, PA-phosphatase related
EIZ62_RS26175	COG0477	Major facilitator Superfamily
EIZ62_RS26180	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS26185	COG1799	cell septum assembly
EIZ62_RS26220	COG0641	radical SAM
EIZ62_RS26250	COG0587	DNA-directed DNA polymerase activity
EIZ62_RS26255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIZ62_RS26290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EIZ62_RS26295	COG4565	transcriptional regulatory protein
EIZ62_RS26340	COG2755	lipolytic protein G-D-S-L family
EIZ62_RS26350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EIZ62_RS26375	COG2188	Transcriptional regulator
EIZ62_RS26380	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EIZ62_RS26385	COG0243	molybdopterin cofactor binding
EIZ62_RS26390	COG2851	Citrate transporter
EIZ62_RS26435	COG0477	Major facilitator Superfamily
EIZ62_RS26440	COG0697	spore germination
EIZ62_RS26445	COG0640	Transcriptional regulator
EIZ62_RS26455	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS26475	COG0789	Transcriptional regulator
EIZ62_RS26505	COG3876	Protein conserved in bacteria
EIZ62_RS26510	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS26515	COG0318	PFAM AMP-dependent synthetase and ligase
EIZ62_RS26520	COG1309	transcriptional regulator
EIZ62_RS26530	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS26545	COG0604	alcohol dehydrogenase
EIZ62_RS26545	COG3321	synthase
EIZ62_RS26545	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS26555	COG2149	membrane
EIZ62_RS26560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EIZ62_RS26565	COG3573	Dehydrogenase
EIZ62_RS26590	COG3265	gluconokinase activity
EIZ62_RS26595	COG2186	Transcriptional regulator
EIZ62_RS26600	COG1113	amino acid transport
EIZ62_RS26615	COG0564	pseudouridine synthase activity
EIZ62_RS26640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIZ62_RS26670	COG0667	Aldo Keto reductase
EIZ62_RS26675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIZ62_RS26685	COG0598	Magnesium transport protein CorA
EIZ62_RS26705	COG0215	cysteine-tRNA ligase activity
EIZ62_RS26715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EIZ62_RS26720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EIZ62_RS26725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EIZ62_RS26730	COG1414	Transcriptional regulator
EIZ62_RS26735	COG0646	methionine synthase
EIZ62_RS26735	COG1410	methionine synthase
EIZ62_RS26745	COG4166	transmembrane transport
EIZ62_RS26755	COG2197	response regulator
EIZ62_RS26765	COG1994	Peptidase M50
EIZ62_RS26765	COG0517	IMP dehydrogenase activity
EIZ62_RS26785	COG1222	aaa ATPase
EIZ62_RS26790	COG4122	O-methyltransferase activity
EIZ62_RS26800	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EIZ62_RS26805	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EIZ62_RS26810	COG1609	Transcriptional regulator
EIZ62_RS26820	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EIZ62_RS26825	COG0545	Peptidyl-prolyl cis-trans isomerase
EIZ62_RS26835	COG2378	regulation of single-species biofilm formation
EIZ62_RS26855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIZ62_RS26860	COG0805	protein transport
EIZ62_RS26905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIZ62_RS26930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EIZ62_RS26935	COG0531	amino acid
EIZ62_RS26940	COG2186	Transcriptional regulator
EIZ62_RS26945	COG0174	glutamine synthetase
EIZ62_RS26950	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS26955	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS27000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EIZ62_RS27005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EIZ62_RS27010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EIZ62_RS27015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIZ62_RS27020	COG5002	protein histidine kinase activity
EIZ62_RS27025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EIZ62_RS27030	COG0072	phenylalanine-tRNA ligase activity
EIZ62_RS27030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIZ62_RS27060	COG1649	PFAM Uncharacterised BCR, COG1649
EIZ62_RS27075	COG2813	Specifically methylates the guanine in position
EIZ62_RS27095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EIZ62_RS27100	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EIZ62_RS27105	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EIZ62_RS27110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIZ62_RS27115	COG1438	arginine binding
EIZ62_RS27125	COG0137	argininosuccinate synthase activity
EIZ62_RS27130	COG0165	Argininosuccinate lyase
EIZ62_RS27145	COG0477	Major facilitator Superfamily
EIZ62_RS27155	COG0584	glycerophosphoryl diester phosphodiesterase
EIZ62_RS27180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EIZ62_RS27185	COG2011	ABC-type metal ion transport system permease component
EIZ62_RS27190	COG1464	Belongs to the NlpA lipoprotein family
EIZ62_RS27205	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EIZ62_RS27210	COG1648	precorrin-2 dehydrogenase activity
EIZ62_RS27210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EIZ62_RS27265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EIZ62_RS27275	COG0456	acetyltransferase
EIZ62_RS27275	COG0454	-acetyltransferase
EIZ62_RS27330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EIZ62_RS27345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EIZ62_RS27370	COG1560	Kdo2-lipid A biosynthetic process
EIZ62_RS27375	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS27390	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EIZ62_RS27395	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EIZ62_RS27400	COG0217	transcriptional regulatory protein
EIZ62_RS27405	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EIZ62_RS27410	COG0632	four-way junction helicase activity
EIZ62_RS27415	COG2255	four-way junction helicase activity
EIZ62_RS27425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIZ62_RS27430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIZ62_RS27435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EIZ62_RS27440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIZ62_RS27445	COG1196	nuclear chromosome segregation
EIZ62_RS27450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EIZ62_RS27460	COG0124	histidyl-tRNA synthetase
EIZ62_RS27480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EIZ62_RS27500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EIZ62_RS27505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EIZ62_RS27510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EIZ62_RS27515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EIZ62_RS27520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EIZ62_RS27525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EIZ62_RS27530	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EIZ62_RS27535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EIZ62_RS27550	COG0006	proline dipeptidase activity
EIZ62_RS27555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EIZ62_RS27560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EIZ62_RS27570	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EIZ62_RS27575	COG0540	Belongs to the ATCase OTCase family
EIZ62_RS27580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EIZ62_RS27590	COG0505	Belongs to the CarA family
EIZ62_RS27595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EIZ62_RS27600	COG0167	dihydroorotate dehydrogenase activity
EIZ62_RS27605	COG0284	orotidine-5'-phosphate decarboxylase activity
EIZ62_RS27615	COG0194	GDP metabolic process
EIZ62_RS27630	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EIZ62_RS27650	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EIZ62_RS27660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EIZ62_RS27665	COG2390	Transcriptional regulator
EIZ62_RS27675	COG1191	sigma factor activity
EIZ62_RS27685	COG2208	phosphoserine phosphatase activity
EIZ62_RS27685	COG2770	Histidine kinase
EIZ62_RS27695	COG2172	sigma factor antagonist activity
EIZ62_RS27700	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS27705	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS27720	COG0531	amino acid
EIZ62_RS27735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EIZ62_RS27755	COG2233	PERMEase
EIZ62_RS27765	COG1940	carbohydrate kinase activity
EIZ62_RS27765	COG1846	Transcriptional regulator
EIZ62_RS27790	COG3201	nicotinamide mononucleotide transporter
EIZ62_RS27795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIZ62_RS27795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIZ62_RS27800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EIZ62_RS27805	COG0140	phosphoribosyl-ATP diphosphatase activity
EIZ62_RS27810	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EIZ62_RS27850	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS27870	COG1216	Glycosyl transferase, family 2
EIZ62_RS27885	COG2270	Major facilitator Superfamily
EIZ62_RS27895	COG2364	Membrane
EIZ62_RS27900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EIZ62_RS27925	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS27930	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS27945	COG1984	allophanate hydrolase subunit 2
EIZ62_RS27950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EIZ62_RS27955	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EIZ62_RS27960	COG2814	Major facilitator Superfamily
EIZ62_RS28015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIZ62_RS28025	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EIZ62_RS28040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EIZ62_RS28050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EIZ62_RS28080	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EIZ62_RS28100	COG1716	ATPase activity
EIZ62_RS28120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIZ62_RS28130	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EIZ62_RS28130	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EIZ62_RS28160	COG1695	Transcriptional regulator
EIZ62_RS28195	COG0697	spore germination
EIZ62_RS28225	COG1864	DNA RNA non-specific endonuclease
EIZ62_RS28225	COG3591	Belongs to the peptidase S1B family
EIZ62_RS28275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EIZ62_RS28300	COG0673	inositol 2-dehydrogenase activity
EIZ62_RS28305	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EIZ62_RS28325	COG1968	undecaprenyl-diphosphatase activity
EIZ62_RS28335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIZ62_RS28365	COG1472	Belongs to the glycosyl hydrolase 3 family
EIZ62_RS28380	COG0110	maltose O-acetyltransferase activity
EIZ62_RS28395	COG1832	CoA-binding protein
EIZ62_RS28400	COG1739	Uncharacterized protein family UPF0029
EIZ62_RS28405	COG0420	3'-5' exonuclease activity
EIZ62_RS28410	COG0419	ATPase involved in DNA repair
EIZ62_RS28415	COG1522	sequence-specific DNA binding
EIZ62_RS28435	COG0626	cystathionine gamma-synthase activity
EIZ62_RS28445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EIZ62_RS28465	COG1595	DNA-templated transcription, initiation
EIZ62_RS28470	COG2188	Transcriptional regulator
EIZ62_RS28475	COG1940	carbohydrate kinase activity
EIZ62_RS28490	COG0583	DNA-binding transcription factor activity
EIZ62_RS28500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EIZ62_RS28525	COG0456	acetyltransferase
EIZ62_RS28540	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS28545	COG2226	methyltransferase
EIZ62_RS28555	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EIZ62_RS28560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EIZ62_RS28565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EIZ62_RS28590	COG0740	serine-type endopeptidase activity
EIZ62_RS28605	COG1309	transcriptional regulator
EIZ62_RS28610	COG0831	urea catabolic process
EIZ62_RS28615	COG0832	Belongs to the urease beta subunit family
EIZ62_RS28620	COG0804	urea catabolic process
EIZ62_RS28625	COG0830	nickel cation binding
EIZ62_RS28630	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EIZ62_RS28635	COG0829	nickel cation binding
EIZ62_RS28645	COG0204	Acyl-transferase
EIZ62_RS28655	COG0515	serine threonine protein kinase
EIZ62_RS28665	COG1132	(ABC) transporter
EIZ62_RS28670	COG1132	(ABC) transporter
EIZ62_RS28675	COG2197	response regulator
EIZ62_RS28685	COG0531	amino acid
EIZ62_RS28700	COG0205	6-phosphofructokinase activity
EIZ62_RS28705	COG3442	glutamine amidotransferase
EIZ62_RS28715	COG0242	peptide deformylase activity
EIZ62_RS28725	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS28735	COG0395	ABC-type sugar transport system, permease component
EIZ62_RS28740	COG1175	transmembrane transport
EIZ62_RS28750	COG0366	Alpha amylase catalytic
EIZ62_RS28755	COG1653	transport
EIZ62_RS28765	COG1136	(ABC) transporter
EIZ62_RS28765	COG0577	efflux transmembrane transporter activity
EIZ62_RS28780	COG0386	Belongs to the glutathione peroxidase family
EIZ62_RS28790	COG1946	Acyl-CoA thioesterase
EIZ62_RS28810	COG1231	oxidoreductase activity
EIZ62_RS28815	COG1132	(ABC) transporter
EIZ62_RS28820	COG1132	(ABC) transporter
EIZ62_RS28845	COG0277	FAD linked oxidase domain protein
EIZ62_RS28855	COG1132	(ABC) transporter
EIZ62_RS28865	COG2072	flavoprotein involved in K transport
EIZ62_RS28875	COG2409	Drug exporters of the RND superfamily
EIZ62_RS28880	COG4585	Histidine kinase
EIZ62_RS28885	COG2197	response regulator
EIZ62_RS28920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIZ62_RS28930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIZ62_RS28940	COG0640	Transcriptional regulator
EIZ62_RS28945	COG1247	-acetyltransferase
EIZ62_RS28955	COG0640	Transcriptional regulator
EIZ62_RS28960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EIZ62_RS28970	COG0546	phosphoglycolate phosphatase activity
EIZ62_RS28980	COG2409	Drug exporters of the RND superfamily
EIZ62_RS29005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EIZ62_RS29015	COG1902	pentaerythritol trinitrate reductase activity
EIZ62_RS29020	COG0640	Transcriptional regulator
EIZ62_RS29040	COG1309	transcriptional regulator
EIZ62_RS29045	COG0671	phosphoesterase, PA-phosphatase related
EIZ62_RS29065	COG0542	response to heat
EIZ62_RS29070	COG0584	glycerophosphoryl diester phosphodiesterase
EIZ62_RS29095	COG0204	Acyl-transferase
EIZ62_RS29115	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EIZ62_RS29125	COG0515	serine threonine protein kinase
EIZ62_RS29130	COG2197	response regulator
EIZ62_RS29135	COG4585	Histidine kinase
EIZ62_RS29165	COG0494	nUDIX hydrolase
EIZ62_RS29170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIZ62_RS29180	COG0445	tRNA wobble uridine modification
EIZ62_RS29240	COG1940	carbohydrate kinase activity
EIZ62_RS29275	COG1349	DNA-binding transcription factor activity
EIZ62_RS29285	COG0464	growth
EIZ62_RS29295	COG0633	Ferredoxin
EIZ62_RS29295	COG3217	Mosc domain protein beta barrel domain protein
EIZ62_RS29305	COG0463	Glycosyl transferase, family 2
EIZ62_RS29330	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS29350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EIZ62_RS29355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EIZ62_RS29365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIZ62_RS29370	COG2197	response regulator
EIZ62_RS29375	COG3851	Histidine kinase
EIZ62_RS29390	COG1309	transcriptional regulator
EIZ62_RS29420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EIZ62_RS29430	COG4172	Belongs to the ABC transporter superfamily
EIZ62_RS29440	COG0601	transmembrane transport
EIZ62_RS29445	COG4166	transmembrane transport
EIZ62_RS29505	COG1819	glycosyl
EIZ62_RS29565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EIZ62_RS29580	COG0515	serine threonine protein kinase
EIZ62_RS29585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EIZ62_RS29595	COG0154	amidase activity
EIZ62_RS29605	COG0006	proline dipeptidase activity
EIZ62_RS29615	COG0513	Belongs to the DEAD box helicase family
EIZ62_RS29625	COG0628	permease
EIZ62_RS29645	COG1120	ATPase activity
EIZ62_RS29670	COG4941	Belongs to the sigma-70 factor family
EIZ62_RS29675	COG3795	YCII-related domain
EIZ62_RS29680	COG1366	Belongs to the anti-sigma-factor antagonist family
EIZ62_RS29685	COG2770	Histidine kinase
EIZ62_RS29685	COG2208	phosphoserine phosphatase activity
EIZ62_RS29690	COG0596	Alpha beta hydrolase
EIZ62_RS29705	COG1295	ribonuclease BN
EIZ62_RS29715	COG0515	serine threonine protein kinase
EIZ62_RS29755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIZ62_RS29775	COG0640	Transcriptional regulator
EIZ62_RS29780	COG0346	lactoylglutathione lyase activity
EIZ62_RS29800	COG2326	polyphosphate kinase activity
EIZ62_RS29805	COG3548	integral membrane protein
EIZ62_RS29815	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EIZ62_RS29825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EIZ62_RS29830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EIZ62_RS29840	COG1181	Belongs to the D-alanine--D-alanine ligase family
EIZ62_RS29845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EIZ62_RS29860	COG1228	amidohydrolase
EIZ62_RS29865	COG0328	RNA-DNA hybrid ribonuclease activity
EIZ62_RS29875	COG0730	response to heat
EIZ62_RS29890	COG0142	geranyltranstransferase activity
EIZ62_RS29925	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EIZ62_RS29935	COG2233	PERMEase
EIZ62_RS29985	COG4106	trans-aconitate 2-methyltransferase activity
EIZ62_RS29990	COG2409	Drug exporters of the RND superfamily
EIZ62_RS29995	COG1032	radical SAM domain protein
EIZ62_RS30000	COG2124	cytochrome p450
EIZ62_RS30015	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EIZ62_RS30020	COG0477	Major facilitator Superfamily
EIZ62_RS30050	COG3387	PFAM Glycoside hydrolase 15-related
EIZ62_RS30120	COG4221	oxidoreductase activity
EIZ62_RS30135	COG0726	polysaccharide deacetylase
EIZ62_RS30145	COG3290	protein histidine kinase activity
EIZ62_RS30165	COG0463	Glycosyl transferase, family 2
EIZ62_RS30205	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EIZ62_RS30205	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EIZ62_RS30210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EIZ62_RS30215	COG0438	transferase activity, transferring glycosyl groups
EIZ62_RS30225	COG2192	nodulation
EIZ62_RS30230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIZ62_RS30235	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EIZ62_RS30250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EIZ62_RS30265	COG0367	asparagine synthase
EIZ62_RS30275	COG2814	Major facilitator Superfamily
EIZ62_RS30285	COG1070	Carbohydrate kinase
EIZ62_RS30290	COG1070	Carbohydrate kinase
EIZ62_RS30295	COG0588	phosphoglycerate mutase activity
EIZ62_RS30310	COG2271	Major facilitator Superfamily
EIZ62_RS30325	COG1982	Orn Lys Arg decarboxylase major
EIZ62_RS30340	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS30350	COG0753	catalase activity
EIZ62_RS30390	COG1733	regulation of RNA biosynthetic process
EIZ62_RS30395	COG1126	abc transporter atp-binding protein
EIZ62_RS30400	COG0765	amino acid transport
EIZ62_RS30405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIZ62_RS30415	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EIZ62_RS30445	COG2197	response regulator
EIZ62_RS30465	COG0583	DNA-binding transcription factor activity
EIZ62_RS30475	COG1278	Cold shock
EIZ62_RS30510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EIZ62_RS30555	COG0446	pyridine nucleotide-disulphide oxidoreductase
EIZ62_RS30555	COG1902	pentaerythritol trinitrate reductase activity
EIZ62_RS30560	COG1122	ATPase activity
EIZ62_RS30570	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EIZ62_RS30575	COG0310	cobalt ion transport
EIZ62_RS30585	COG1461	Dihydroxyacetone kinase
EIZ62_RS30590	COG2376	Dihydroxyacetone kinase
EIZ62_RS30620	COG4213	ABC transporter substrate-binding protein
EIZ62_RS30630	COG4214	carbohydrate transport
EIZ62_RS30685	COG1309	transcriptional regulator
EIZ62_RS30695	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS30705	COG1295	ribonuclease BN
EIZ62_RS30715	COG0435	Glutathione S-transferase
EIZ62_RS30730	COG1796	DNA polymerase
EIZ62_RS30730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EIZ62_RS30770	COG2223	nitrite transmembrane transporter activity
EIZ62_RS30785	COG0723	plastoquinol--plastocyanin reductase activity
EIZ62_RS30785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIZ62_RS30790	COG2890	protein-(glutamine-N5) methyltransferase activity
EIZ62_RS30810	COG1960	acyl-CoA dehydrogenase activity
EIZ62_RS30820	COG0515	serine threonine protein kinase
EIZ62_RS30840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIZ62_RS30845	COG2070	2-Nitropropane dioxygenase
EIZ62_RS30855	COG0387	Pfam Sodium calcium exchanger
EIZ62_RS30860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EIZ62_RS30860	COG3433	isochorismatase activity
EIZ62_RS30860	COG2226	methyltransferase
EIZ62_RS30875	COG1280	lysine exporter protein (LysE YggA)
EIZ62_RS30880	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EIZ62_RS30905	COG1024	Enoyl-CoA hydratase
EIZ62_RS30935	COG1695	Transcriptional regulator
EIZ62_RS31015	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS31075	COG0346	lactoylglutathione lyase activity
EIZ62_RS31100	COG0076	glutamate decarboxylase activity
EIZ62_RS31145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIZ62_RS31160	COG0009	L-threonylcarbamoyladenylate synthase
EIZ62_RS31185	COG0402	S-adenosylhomocysteine deaminase activity
EIZ62_RS31210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIZ62_RS31260	COG4977	sequence-specific DNA binding
EIZ62_RS31280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIZ62_RS31330	COG3739	integral membrane protein
EIZ62_RS31375	COG0789	Transcriptional regulator
EIZ62_RS31390	COG1132	(ABC) transporter
EIZ62_RS31390	COG2375	cellular response to nickel ion
EIZ62_RS31445	COG1012	belongs to the aldehyde dehydrogenase family
EIZ62_RS31450	COG0515	serine threonine protein kinase
EIZ62_RS31460	COG1473	amidohydrolase
EIZ62_RS31480	COG4191	Histidine kinase
EIZ62_RS31485	COG2356	endonuclease I
EIZ62_RS31510	COG1595	DNA-templated transcription, initiation
EIZ62_RS31515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EIZ62_RS31530	COG1191	sigma factor activity
EIZ62_RS31535	COG0784	Response regulator, receiver
EIZ62_RS31540	COG4251	negative regulation of phosphorylation
EIZ62_RS31560	COG1028	Short-chain dehydrogenase reductase Sdr
EIZ62_RS31605	COG2226	methyltransferase
EIZ62_RS31610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EIZ62_RS31625	COG1846	Transcriptional regulator
EIZ62_RS31640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EIZ62_RS31645	COG2226	methyltransferase
EIZ62_RS31655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EIZ62_RS31670	COG3321	synthase
EIZ62_RS31670	COG0604	alcohol dehydrogenase
EIZ62_RS31695	COG1309	transcriptional regulator
EIZ62_RS31700	COG0277	FAD linked oxidase domain protein
EIZ62_RS31710	COG0477	Major facilitator Superfamily
EIZ62_RS31735	COG1309	transcriptional regulator