locus-tag	class	description
LL041_RS00240	COG2814	Major facilitator Superfamily
LL041_RS00255	COG0300	oxidoreductase activity
LL041_RS00260	COG3321	synthase
LL041_RS00265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL041_RS00270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS00275	COG1024	Enoyl-CoA hydratase
LL041_RS00280	COG1024	Enoyl-CoA hydratase
LL041_RS00285	COG3425	synthase
LL041_RS00290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL041_RS00295	COG2070	2-Nitropropane dioxygenase
LL041_RS00295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL041_RS00300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS00300	COG0300	oxidoreductase activity
LL041_RS00300	COG3321	synthase
LL041_RS00300	COG4221	oxidoreductase activity
LL041_RS00305	COG3321	synthase
LL041_RS00305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS00305	COG0300	oxidoreductase activity
LL041_RS00305	COG4221	oxidoreductase activity
LL041_RS00320	COG0300	oxidoreductase activity
LL041_RS00320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS00320	COG4221	oxidoreductase activity
LL041_RS00320	COG3321	synthase
LL041_RS00325	COG4221	oxidoreductase activity
LL041_RS00325	COG0300	oxidoreductase activity
LL041_RS00325	COG3321	synthase
LL041_RS00325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS00330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS00330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LL041_RS00330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS00330	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS00330	COG3321	synthase
LL041_RS00340	COG2124	cytochrome p450
LL041_RS00390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LL041_RS00390	COG0515	serine threonine protein kinase
LL041_RS00410	COG0667	Aldo Keto reductase
LL041_RS00435	COG0395	ABC-type sugar transport system, permease component
LL041_RS00535	COG0346	lactoylglutathione lyase activity
LL041_RS00540	COG0640	Transcriptional regulator
LL041_RS00555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL041_RS00590	COG0667	Aldo Keto reductase
LL041_RS00615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL041_RS00620	COG4948	Mandelate Racemase Muconate Lactonizing
LL041_RS00625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL041_RS00630	COG0747	negative chemotaxis
LL041_RS00635	COG0601	transmembrane transport
LL041_RS00640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL041_RS00645	COG0444	Belongs to the ABC transporter superfamily
LL041_RS00650	COG4608	Belongs to the ABC transporter superfamily
LL041_RS00715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL041_RS00720	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL041_RS00730	COG1129	ABC transporter
LL041_RS00735	COG1869	D-ribose catabolic process
LL041_RS00740	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LL041_RS00745	COG2188	Transcriptional regulator
LL041_RS00755	COG1733	regulation of RNA biosynthetic process
LL041_RS00780	COG0596	Alpha beta hydrolase
LL041_RS00795	COG0531	amino acid
LL041_RS00810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL041_RS00815	COG1309	transcriptional regulator
LL041_RS00835	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS00840	COG0183	Belongs to the thiolase family
LL041_RS00850	COG0604	alcohol dehydrogenase
LL041_RS00850	COG3321	synthase
LL041_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS00855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL041_RS00860	COG1021	2,3-dihydroxybenzoate-AMP ligase
LL041_RS00870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LL041_RS00875	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS00880	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS00890	COG1960	acyl-CoA dehydrogenase activity
LL041_RS00895	COG1024	Enoyl-CoA hydratase
LL041_RS00905	COG0477	Major facilitator Superfamily
LL041_RS00915	COG2815	serine threonine protein kinase
LL041_RS00915	COG0515	serine threonine protein kinase
LL041_RS00925	COG0514	ATP-dependent DNA helicase (RecQ)
LL041_RS00960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LL041_RS00990	COG0604	alcohol dehydrogenase
LL041_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS00990	COG3321	synthase
LL041_RS01015	COG0477	Major facilitator Superfamily
LL041_RS01025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LL041_RS01025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LL041_RS01055	COG2755	lipolytic protein G-D-S-L family
LL041_RS01085	COG0456	acetyltransferase
LL041_RS01090	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LL041_RS01105	COG0583	DNA-binding transcription factor activity
LL041_RS01115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LL041_RS01135	COG1891	lyase activity
LL041_RS01150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LL041_RS01155	COG1022	Amp-dependent synthetase and ligase
LL041_RS01160	COG1024	Enoyl-CoA hydratase
LL041_RS01160	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS01165	COG0183	Belongs to the thiolase family
LL041_RS01175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL041_RS01180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL041_RS01200	COG1309	transcriptional regulator
LL041_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS01250	COG2378	regulation of single-species biofilm formation
LL041_RS01265	COG2045	Belongs to the ComB family
LL041_RS01340	COG0803	Belongs to the bacterial solute-binding protein 9 family
LL041_RS01350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LL041_RS01355	COG1120	ATPase activity
LL041_RS01365	COG1595	DNA-templated transcription, initiation
LL041_RS01370	COG0738	Major facilitator superfamily
LL041_RS01380	COG1120	ATPase activity
LL041_RS01385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL041_RS01405	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS01410	COG3844	kynureninase activity
LL041_RS01420	COG3483	tryptophan 2,3-dioxygenase activity
LL041_RS01425	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS01430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LL041_RS01435	COG2151	metal-sulfur cluster biosynthetic enzyme
LL041_RS01440	COG3396	Phenylacetate-CoA oxygenase
LL041_RS01450	COG3396	Phenylacetate-CoA oxygenase
LL041_RS01460	COG0318	PFAM AMP-dependent synthetase and ligase
LL041_RS01475	COG0604	alcohol dehydrogenase
LL041_RS01485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS01490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS01495	COG1595	DNA-templated transcription, initiation
LL041_RS01535	COG0656	L-ascorbic acid biosynthetic process
LL041_RS01560	COG1733	regulation of RNA biosynthetic process
LL041_RS01565	COG2945	thiolester hydrolase activity
LL041_RS01565	COG0596	Alpha beta hydrolase
LL041_RS01595	COG3940	Belongs to the glycosyl hydrolase 43 family
LL041_RS01600	COG1846	Transcriptional regulator
LL041_RS01605	COG2409	Drug exporters of the RND superfamily
LL041_RS01610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LL041_RS01625	COG2259	Doxx family
LL041_RS01685	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LL041_RS01690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LL041_RS01715	COG0714	Associated with various cellular activities
LL041_RS01795	COG0667	Aldo Keto reductase
LL041_RS01820	COG0395	ABC-type sugar transport system, permease component
LL041_RS01825	COG1175	transmembrane transport
LL041_RS01845	COG1609	Transcriptional regulator
LL041_RS01855	COG1129	ABC transporter
LL041_RS01860	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL041_RS01865	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL041_RS01895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LL041_RS01900	COG0702	epimerase
LL041_RS01920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL041_RS01945	COG2124	cytochrome p450
LL041_RS01955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LL041_RS01965	COG4941	Belongs to the sigma-70 factor family
LL041_RS01970	COG3795	YCII-related domain
LL041_RS01975	COG1309	transcriptional regulator
LL041_RS01980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LL041_RS01990	COG0183	Belongs to the thiolase family
LL041_RS01995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LL041_RS02015	COG1414	Transcriptional regulator
LL041_RS02040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LL041_RS02055	COG2259	Doxx family
LL041_RS02105	COG0395	ABC-type sugar transport system, permease component
LL041_RS02110	COG1175	transmembrane transport
LL041_RS02115	COG1653	transport
LL041_RS02120	COG1501	Belongs to the glycosyl hydrolase 31 family
LL041_RS02125	COG2326	polyphosphate kinase activity
LL041_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS02145	COG4209	transmembrane transport
LL041_RS02150	COG0395	ABC-type sugar transport system, permease component
LL041_RS02170	COG0110	maltose O-acetyltransferase activity
LL041_RS02180	COG0714	Associated with various cellular activities
LL041_RS02195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL041_RS02205	COG1120	ATPase activity
LL041_RS02225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LL041_RS02235	COG3290	protein histidine kinase activity
LL041_RS02245	COG0326	Molecular chaperone. Has ATPase activity
LL041_RS02270	COG0667	Aldo Keto reductase
LL041_RS02290	COG0559	Belongs to the binding-protein-dependent transport system permease family
LL041_RS02300	COG0410	ABC transporter
LL041_RS02305	COG2508	Transcriptional regulator
LL041_RS02360	COG3290	protein histidine kinase activity
LL041_RS02385	COG1017	nitric oxide dioxygenase activity
LL041_RS02385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LL041_RS02455	COG1132	(ABC) transporter
LL041_RS02460	COG0667	Aldo Keto reductase
LL041_RS02465	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LL041_RS02470	COG0673	inositol 2-dehydrogenase activity
LL041_RS02495	COG1554	hydrolase, family 65, central catalytic
LL041_RS02545	COG1309	transcriptional regulator
LL041_RS02565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LL041_RS02605	COG1132	(ABC) transporter
LL041_RS02695	COG0248	Ppx GppA phosphatase
LL041_RS02710	COG2890	protein-(glutamine-N5) methyltransferase activity
LL041_RS02770	COG0667	Aldo Keto reductase
LL041_RS02790	COG0435	Glutathione S-transferase
LL041_RS02825	COG1796	DNA polymerase
LL041_RS02825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LL041_RS02840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LL041_RS02870	COG2706	6-phosphogluconolactonase activity
LL041_RS02880	COG1309	transcriptional regulator
LL041_RS02905	COG1609	Transcriptional regulator
LL041_RS02925	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL041_RS02930	COG1129	ABC transporter
LL041_RS02935	COG4952	isomerase
LL041_RS02940	COG3347	Dehydrogenase
LL041_RS02940	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS02945	COG1070	Carbohydrate kinase
LL041_RS02950	COG0247	lactate metabolic process
LL041_RS02955	COG1139	Iron-sulfur cluster binding protein
LL041_RS02960	COG1556	Lactate utilization protein
LL041_RS02965	COG0577	efflux transmembrane transporter activity
LL041_RS02965	COG1136	(ABC) transporter
LL041_RS02975	COG0542	response to heat
LL041_RS03025	COG4585	Histidine kinase
LL041_RS03030	COG2197	response regulator
LL041_RS03045	COG0242	peptide deformylase activity
LL041_RS03055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL041_RS03060	COG1609	Transcriptional regulator
LL041_RS03080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL041_RS03085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LL041_RS03090	COG2080	2 iron, 2 sulfur cluster binding
LL041_RS03100	COG0583	DNA-binding transcription factor activity
LL041_RS03110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL041_RS03130	COG1881	PFAM PEBP family protein
LL041_RS03150	COG1335	isochorismatase
LL041_RS03180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LL041_RS03185	COG0121	glutamine amidotransferase
LL041_RS03190	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LL041_RS03195	COG2182	Extracellular solute-binding protein
LL041_RS03200	COG3360	Dodecin
LL041_RS03210	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
LL041_RS03225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LL041_RS03230	COG1053	succinate dehydrogenase
LL041_RS03240	COG0583	DNA-binding transcription factor activity
LL041_RS03250	COG0726	polysaccharide deacetylase
LL041_RS03315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LL041_RS03360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LL041_RS03365	COG0297	glycogen (starch) synthase activity
LL041_RS03385	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LL041_RS03400	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LL041_RS03415	COG3693	PFAM glycoside hydrolase, family 10
LL041_RS03415	COG3507	Belongs to the glycosyl hydrolase 43 family
LL041_RS03415	COG2382	esterase
LL041_RS03425	COG3693	PFAM glycoside hydrolase, family 10
LL041_RS03450	COG0179	Fumarylacetoacetate (FAA) hydrolase
LL041_RS03455	COG4948	Mandelate Racemase Muconate Lactonizing
LL041_RS03480	COG0277	FAD linked oxidase domain protein
LL041_RS03480	COG0247	lactate metabolic process
LL041_RS03485	COG0028	Belongs to the TPP enzyme family
LL041_RS03490	COG4948	Mandelate Racemase Muconate Lactonizing
LL041_RS03500	COG0300	oxidoreductase activity
LL041_RS03515	COG0513	Belongs to the DEAD box helicase family
LL041_RS03520	COG1132	(ABC) transporter
LL041_RS03525	COG2860	membrane
LL041_RS03535	COG1595	DNA-templated transcription, initiation
LL041_RS03570	COG0366	Alpha amylase catalytic
LL041_RS03570	COG1874	Beta-galactosidase
LL041_RS03580	COG1472	Belongs to the glycosyl hydrolase 3 family
LL041_RS03590	COG1175	transmembrane transport
LL041_RS03595	COG1653	transport
LL041_RS03600	COG1609	Transcriptional regulator
LL041_RS03610	COG0395	ABC-type sugar transport system, permease component
LL041_RS03675	COG4585	Histidine kinase
LL041_RS03680	COG2197	response regulator
LL041_RS03690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LL041_RS03695	COG1132	(ABC) transporter
LL041_RS03705	COG0668	transmembrane transport
LL041_RS03710	COG2838	Isocitrate dehydrogenase
LL041_RS03755	COG2814	Major facilitator Superfamily
LL041_RS03770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LL041_RS03775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL041_RS03780	COG2188	Transcriptional regulator
LL041_RS03785	COG0673	inositol 2-dehydrogenase activity
LL041_RS03790	COG1609	Transcriptional regulator
LL041_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS03805	COG0673	inositol 2-dehydrogenase activity
LL041_RS03810	COG0673	inositol 2-dehydrogenase activity
LL041_RS03815	COG1312	Catalyzes the dehydration of D-mannonate
LL041_RS03835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL041_RS03845	COG3718	enzyme involved in inositol metabolism
LL041_RS03850	COG3962	Belongs to the TPP enzyme family
LL041_RS03855	COG2188	Transcriptional regulator
LL041_RS03900	COG0183	Belongs to the thiolase family
LL041_RS03955	COG3959	Transketolase, thiamine diphosphate binding domain
LL041_RS03960	COG3958	Transketolase
LL041_RS03985	COG2010	Cytochrome c
LL041_RS03985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL041_RS03995	COG0191	fructose-bisphosphate aldolase activity
LL041_RS04005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LL041_RS04010	COG0395	ABC-type sugar transport system, permease component
LL041_RS04025	COG1349	DNA-binding transcription factor activity
LL041_RS04035	COG0673	inositol 2-dehydrogenase activity
LL041_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS04075	COG1215	transferase activity, transferring glycosyl groups
LL041_RS04105	COG1349	DNA-binding transcription factor activity
LL041_RS04135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LL041_RS04140	COG1940	carbohydrate kinase activity
LL041_RS04150	COG2813	Specifically methylates the guanine in position
LL041_RS04155	COG3387	PFAM Glycoside hydrolase 15-related
LL041_RS04180	COG0673	inositol 2-dehydrogenase activity
LL041_RS04230	COG2197	response regulator
LL041_RS04235	COG4585	Histidine kinase
LL041_RS04250	COG1660	Displays ATPase and GTPase activities
LL041_RS04285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LL041_RS04335	COG0584	glycerophosphoryl diester phosphodiesterase
LL041_RS04370	COG0671	phosphoesterase, PA-phosphatase related
LL041_RS04375	COG1309	transcriptional regulator
LL041_RS04400	COG0640	Transcriptional regulator
LL041_RS04405	COG1902	pentaerythritol trinitrate reductase activity
LL041_RS04420	COG1960	acyl-CoA dehydrogenase activity
LL041_RS04430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LL041_RS04455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL041_RS04500	COG0589	response to stress
LL041_RS04515	COG0477	Major facilitator Superfamily
LL041_RS04525	COG0432	Pfam Uncharacterised protein family UPF0047
LL041_RS04530	COG2072	flavoprotein involved in K transport
LL041_RS04535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LL041_RS04540	COG1132	(ABC) transporter
LL041_RS04550	COG1132	(ABC) transporter
LL041_RS04555	COG1132	(ABC) transporter
LL041_RS04565	COG0254	rRNA binding
LL041_RS04580	COG1946	Acyl-CoA thioesterase
LL041_RS04590	COG2018	Roadblock/LC7 domain
LL041_RS04630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LL041_RS04675	COG1960	acyl-CoA dehydrogenase activity
LL041_RS04680	COG1960	acyl-CoA dehydrogenase activity
LL041_RS04700	COG1793	dna ligase
LL041_RS04710	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS04725	COG1960	acyl-CoA dehydrogenase activity
LL041_RS04735	COG0242	peptide deformylase activity
LL041_RS04740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LL041_RS04745	COG3442	glutamine amidotransferase
LL041_RS04750	COG0205	6-phosphofructokinase activity
LL041_RS04770	COG3275	phosphorelay sensor kinase activity
LL041_RS04775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL041_RS04790	COG1522	sequence-specific DNA binding
LL041_RS04795	COG1834	amidinotransferase
LL041_RS04800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LL041_RS04820	COG0204	Acyl-transferase
LL041_RS04830	COG0829	nickel cation binding
LL041_RS04835	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LL041_RS04845	COG0804	urea catabolic process
LL041_RS04850	COG0832	Belongs to the urease beta subunit family
LL041_RS04855	COG0831	urea catabolic process
LL041_RS04865	COG0740	serine-type endopeptidase activity
LL041_RS04900	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LL041_RS04905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LL041_RS04910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LL041_RS04915	COG2226	methyltransferase
LL041_RS04930	COG1136	(ABC) transporter
LL041_RS04930	COG0577	efflux transmembrane transporter activity
LL041_RS04940	COG0456	acetyltransferase
LL041_RS05075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LL041_RS05100	COG4585	Histidine kinase
LL041_RS05105	COG2197	response regulator
LL041_RS05110	COG1940	carbohydrate kinase activity
LL041_RS05115	COG2188	Transcriptional regulator
LL041_RS05120	COG1595	DNA-templated transcription, initiation
LL041_RS05130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL041_RS05145	COG0626	cystathionine gamma-synthase activity
LL041_RS05170	COG0419	ATPase involved in DNA repair
LL041_RS05175	COG0420	3'-5' exonuclease activity
LL041_RS05180	COG1739	Uncharacterized protein family UPF0029
LL041_RS05190	COG0215	cysteine-tRNA ligase activity
LL041_RS05195	COG1832	CoA-binding protein
LL041_RS05200	COG0640	Transcriptional regulator
LL041_RS05220	COG0110	maltose O-acetyltransferase activity
LL041_RS05255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LL041_RS05275	COG1968	undecaprenyl-diphosphatase activity
LL041_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS05300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LL041_RS05310	COG2318	DinB family
LL041_RS05325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LL041_RS05390	COG0697	spore germination
LL041_RS05450	COG1733	regulation of RNA biosynthetic process
LL041_RS05465	COG0725	ABC transporter, periplasmic molybdate-binding protein
LL041_RS05480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LL041_RS05480	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LL041_RS05490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LL041_RS05510	COG1716	ATPase activity
LL041_RS05530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LL041_RS05560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LL041_RS05570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LL041_RS05585	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LL041_RS05605	COG2018	Roadblock/LC7 domain
LL041_RS05645	COG2814	Major facilitator Superfamily
LL041_RS05650	COG4336	lyase activity
LL041_RS05655	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LL041_RS05660	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LL041_RS05665	COG1984	allophanate hydrolase subunit 2
LL041_RS05675	COG0438	transferase activity, transferring glycosyl groups
LL041_RS05680	COG0438	transferase activity, transferring glycosyl groups
LL041_RS05710	COG2364	Membrane
LL041_RS05720	COG2270	Major facilitator Superfamily
LL041_RS05730	COG3030	protein affecting phage T7 exclusion by the F plasmid
LL041_RS05735	COG0463	Glycosyl transferase, family 2
LL041_RS05755	COG1960	acyl-CoA dehydrogenase activity
LL041_RS05805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LL041_RS05810	COG0140	phosphoribosyl-ATP diphosphatase activity
LL041_RS05815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LL041_RS05820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LL041_RS05820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LL041_RS05825	COG3201	nicotinamide mononucleotide transporter
LL041_RS05835	COG1090	epimerase
LL041_RS05840	COG1940	carbohydrate kinase activity
LL041_RS05840	COG1846	Transcriptional regulator
LL041_RS05845	COG2223	nitrite transmembrane transporter activity
LL041_RS05855	COG2233	PERMEase
LL041_RS05875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LL041_RS05890	COG0531	amino acid
LL041_RS05905	COG2390	Transcriptional regulator
LL041_RS05910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LL041_RS05915	COG2409	Drug exporters of the RND superfamily
LL041_RS05925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LL041_RS05940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LL041_RS05950	COG1758	RNA polymerase activity
LL041_RS05955	COG0194	GDP metabolic process
LL041_RS05965	COG0284	orotidine-5'-phosphate decarboxylase activity
LL041_RS05970	COG0167	dihydroorotate dehydrogenase activity
LL041_RS05975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LL041_RS05980	COG0505	Belongs to the CarA family
LL041_RS05990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LL041_RS05995	COG0540	Belongs to the ATCase OTCase family
LL041_RS06000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LL041_RS06010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LL041_RS06015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LL041_RS06020	COG0006	proline dipeptidase activity
LL041_RS06030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LL041_RS06035	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LL041_RS06040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LL041_RS06050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LL041_RS06060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LL041_RS06065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LL041_RS06080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LL041_RS06095	COG0124	histidyl-tRNA synthetase
LL041_RS06105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LL041_RS06110	COG1196	nuclear chromosome segregation
LL041_RS06115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LL041_RS06120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LL041_RS06125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LL041_RS06130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LL041_RS06140	COG2255	four-way junction helicase activity
LL041_RS06145	COG0632	four-way junction helicase activity
LL041_RS06150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LL041_RS06155	COG0217	transcriptional regulatory protein
LL041_RS06160	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LL041_RS06165	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LL041_RS06175	COG0438	transferase activity, transferring glycosyl groups
LL041_RS06180	COG1560	Kdo2-lipid A biosynthetic process
LL041_RS06185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LL041_RS06205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LL041_RS06220	COG2176	DNA-directed DNA polymerase activity
LL041_RS06220	COG5002	protein histidine kinase activity
LL041_RS06245	COG0395	ABC-type sugar transport system, permease component
LL041_RS06250	COG1175	transmembrane transport
LL041_RS06305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LL041_RS06365	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LL041_RS06370	COG0475	glutathione-regulated potassium exporter activity
LL041_RS06375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LL041_RS06405	COG1960	acyl-CoA dehydrogenase activity
LL041_RS06420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS06455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL041_RS06480	COG1648	precorrin-2 dehydrogenase activity
LL041_RS06480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LL041_RS06485	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LL041_RS06500	COG1464	Belongs to the NlpA lipoprotein family
LL041_RS06505	COG2011	ABC-type metal ion transport system permease component
LL041_RS06510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LL041_RS06540	COG0584	glycerophosphoryl diester phosphodiesterase
LL041_RS06545	COG0204	Acyl-transferase
LL041_RS06545	COG0318	PFAM AMP-dependent synthetase and ligase
LL041_RS06550	COG0477	Major facilitator Superfamily
LL041_RS06565	COG0165	Argininosuccinate lyase
LL041_RS06570	COG0137	argininosuccinate synthase activity
LL041_RS06605	COG1438	arginine binding
LL041_RS06610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LL041_RS06615	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LL041_RS06620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LL041_RS06625	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LL041_RS06635	COG2259	Doxx family
LL041_RS06665	COG0697	spore germination
LL041_RS06675	COG1649	PFAM Uncharacterised BCR, COG1649
LL041_RS06700	COG0072	phenylalanine-tRNA ligase activity
LL041_RS06700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL041_RS06705	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LL041_RS06710	COG5002	protein histidine kinase activity
LL041_RS06715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LL041_RS06720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LL041_RS06725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LL041_RS06730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LL041_RS06775	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS06780	COG0174	glutamine synthetase
LL041_RS06790	COG0531	amino acid
LL041_RS06795	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LL041_RS06810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LL041_RS06820	COG4176	ABC-type proline glycine betaine transport system permease component
LL041_RS06825	COG0517	IMP dehydrogenase activity
LL041_RS06825	COG4175	Glycine betaine
LL041_RS06830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL041_RS06845	COG0564	pseudouridine synthase activity
LL041_RS06885	COG0805	protein transport
LL041_RS06890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LL041_RS06910	COG2378	regulation of single-species biofilm formation
LL041_RS06920	COG0545	Peptidyl-prolyl cis-trans isomerase
LL041_RS06925	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LL041_RS06935	COG1609	Transcriptional regulator
LL041_RS06940	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LL041_RS06945	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LL041_RS06960	COG4122	O-methyltransferase activity
LL041_RS06965	COG1222	aaa ATPase
LL041_RS06985	COG1994	Peptidase M50
LL041_RS06985	COG0517	IMP dehydrogenase activity
LL041_RS06995	COG2197	response regulator
LL041_RS07000	COG4166	transmembrane transport
LL041_RS07005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL041_RS07010	COG1410	methionine synthase
LL041_RS07010	COG0646	methionine synthase
LL041_RS07015	COG1414	Transcriptional regulator
LL041_RS07020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LL041_RS07025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LL041_RS07030	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LL041_RS07035	COG2186	Transcriptional regulator
LL041_RS07045	COG0215	cysteine-tRNA ligase activity
LL041_RS07060	COG0588	phosphoglycerate mutase activity
LL041_RS07065	COG0598	Magnesium transport protein CorA
LL041_RS07075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL041_RS07080	COG0667	Aldo Keto reductase
LL041_RS07110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL041_RS07120	COG3012	SEC-C Motif Domain Protein
LL041_RS07125	COG2186	Transcriptional regulator
LL041_RS07130	COG3265	gluconokinase activity
LL041_RS07165	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LL041_RS07170	COG2149	membrane
LL041_RS07190	COG1960	acyl-CoA dehydrogenase activity
LL041_RS07215	COG3876	Protein conserved in bacteria
LL041_RS07245	COG1960	acyl-CoA dehydrogenase activity
LL041_RS07255	COG0640	Transcriptional regulator
LL041_RS07280	COG2851	Citrate transporter
LL041_RS07285	COG0243	molybdopterin cofactor binding
LL041_RS07290	COG1309	transcriptional regulator
LL041_RS07300	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LL041_RS07305	COG2188	Transcriptional regulator
LL041_RS07340	COG1595	DNA-templated transcription, initiation
LL041_RS07360	COG2815	serine threonine protein kinase
LL041_RS07360	COG0515	serine threonine protein kinase
LL041_RS07365	COG2755	lipolytic protein G-D-S-L family
LL041_RS07380	COG1649	PFAM Uncharacterised BCR, COG1649
LL041_RS07380	COG0726	polysaccharide deacetylase
LL041_RS07395	COG1725	Transcriptional regulator
LL041_RS07440	COG0587	DNA-directed DNA polymerase activity
LL041_RS07465	COG1799	cell septum assembly
LL041_RS07470	COG1960	acyl-CoA dehydrogenase activity
LL041_RS07475	COG0477	Major facilitator Superfamily
LL041_RS07485	COG0671	phosphoesterase, PA-phosphatase related
LL041_RS07515	COG1160	GTP binding
LL041_RS07525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LL041_RS07555	COG1187	pseudouridine synthase activity
LL041_RS07560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LL041_RS07565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LL041_RS07580	COG0686	Belongs to the AlaDH PNT family
LL041_RS07590	COG0494	nUDIX hydrolase
LL041_RS07595	COG0504	CTP synthase activity
LL041_RS07600	COG3387	PFAM Glycoside hydrolase 15-related
LL041_RS07615	COG0497	DNA recombination
LL041_RS07620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LL041_RS07640	COG1120	ATPase activity
LL041_RS07645	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL041_RS07650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL041_RS07655	COG0647	UMP catabolic process
LL041_RS07690	COG2094	Belongs to the DNA glycosylase MPG family
LL041_RS07700	COG1881	PFAM PEBP family protein
LL041_RS07720	COG1119	ATPase activity
LL041_RS07735	COG2197	response regulator
LL041_RS07745	COG4221	oxidoreductase activity
LL041_RS07750	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LL041_RS07760	COG1716	ATPase activity
LL041_RS07760	COG0842	Transport permease protein
LL041_RS07760	COG1131	(ABC) transporter
LL041_RS07770	COG0560	Phosphoserine phosphatase
LL041_RS07770	COG3830	Belongs to the UPF0237 family
LL041_RS07775	COG0588	phosphoglycerate mutase activity
LL041_RS07790	COG2186	Transcriptional regulator
LL041_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS07805	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
LL041_RS07825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LL041_RS07845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LL041_RS07850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL041_RS07870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL041_RS07880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LL041_RS07910	COG3387	PFAM Glycoside hydrolase 15-related
LL041_RS07955	COG1024	Enoyl-CoA hydratase
LL041_RS07965	COG0488	(ABC) transporter
LL041_RS07985	COG0235	Class ii aldolase
LL041_RS08000	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LL041_RS08005	COG1492	cobalamin metabolic process
LL041_RS08025	COG1797	cobyrinic acid a,c-diamide synthase activity
LL041_RS08085	COG0765	amino acid transport
LL041_RS08095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LL041_RS08100	COG0456	acetyltransferase
LL041_RS08105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LL041_RS08110	COG1917	Cupin 2, conserved barrel domain protein
LL041_RS08115	COG5285	phytanoyl-CoA dioxygenase
LL041_RS08120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LL041_RS08140	COG4585	Histidine kinase
LL041_RS08145	COG2197	response regulator
LL041_RS08155	COG1414	Transcriptional regulator
LL041_RS08165	COG0768	penicillin binding
LL041_RS08170	COG1595	DNA-templated transcription, initiation
LL041_RS08185	COG3507	Belongs to the glycosyl hydrolase 43 family
LL041_RS08195	COG4677	pectinesterase activity
LL041_RS08200	COG3866	Pectate lyase
LL041_RS08205	COG2755	lipolytic protein G-D-S-L family
LL041_RS08215	COG3507	Belongs to the glycosyl hydrolase 43 family
LL041_RS08230	COG0395	ABC-type sugar transport system, permease component
LL041_RS08245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL041_RS08250	COG1802	Transcriptional regulator
LL041_RS08270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL041_RS08275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LL041_RS08280	COG1349	DNA-binding transcription factor activity
LL041_RS08295	COG0395	ABC-type sugar transport system, permease component
LL041_RS08300	COG1063	alcohol dehydrogenase
LL041_RS08345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL041_RS08355	COG1595	DNA-templated transcription, initiation
LL041_RS08360	COG2171	N-acyltransferase activity
LL041_RS08370	COG2151	metal-sulfur cluster biosynthetic enzyme
LL041_RS08375	COG0822	iron-sulfur transferase activity
LL041_RS08380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LL041_RS08385	COG0396	ATPase activity
LL041_RS08395	COG0719	Fe-S assembly protein
LL041_RS08410	COG1131	(ABC) transporter
LL041_RS08420	COG1612	heme a metabolic process
LL041_RS08440	COG0109	protoheme IX farnesyltransferase activity
LL041_RS08450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LL041_RS08465	COG0363	glucosamine-6-phosphate deaminase activity
LL041_RS08470	COG0395	ABC-type sugar transport system, permease component
LL041_RS08475	COG1175	transmembrane transport
LL041_RS08480	COG1653	transport
LL041_RS08485	COG0366	Alpha amylase catalytic
LL041_RS08490	COG1653	transport
LL041_RS08495	COG1695	Transcriptional regulator
LL041_RS08500	COG0577	efflux transmembrane transporter activity
LL041_RS08500	COG1136	(ABC) transporter
LL041_RS08515	COG0166	Belongs to the GPI family
LL041_RS08525	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LL041_RS08530	COG0149	triose-phosphate isomerase activity
LL041_RS08535	COG0126	phosphoglycerate kinase activity
LL041_RS08540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LL041_RS08550	COG1481	regulation of sporulation
LL041_RS08555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LL041_RS08560	COG1660	Displays ATPase and GTPase activities
LL041_RS08565	COG0322	excinuclease ABC activity
LL041_RS08580	COG0723	plastoquinol--plastocyanin reductase activity
LL041_RS08585	COG1609	Transcriptional regulator
LL041_RS08590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL041_RS08595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LL041_RS08605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL041_RS08610	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LL041_RS08615	COG0387	Pfam Sodium calcium exchanger
LL041_RS08635	COG0556	nucleotide-excision repair
LL041_RS08645	COG0584	glycerophosphoryl diester phosphodiesterase
LL041_RS08650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LL041_RS08660	COG2313	pseudouridylate synthase activity
LL041_RS08790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LL041_RS08795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LL041_RS08800	COG2267	carboxylic ester hydrolase activity
LL041_RS08810	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LL041_RS08815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LL041_RS08830	COG0237	dephospho-CoA kinase activity
LL041_RS08840	COG0539	negative regulation of cytoplasmic translation
LL041_RS08850	COG1643	Atp-dependent helicase
LL041_RS08880	COG2050	protein possibly involved in aromatic compounds catabolism
LL041_RS08905	COG0411	ABC transporter
LL041_RS08935	COG0737	Belongs to the 5'-nucleotidase family
LL041_RS08940	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LL041_RS08950	COG0745	RESPONSE REGULATOR receiver
LL041_RS08955	COG1605	Chorismate mutase
LL041_RS08955	COG0287	Prephenate dehydrogenase
LL041_RS08965	COG2304	oxidoreductase activity
LL041_RS08985	COG0067	glutamate synthase
LL041_RS08985	COG0069	glutamate synthase activity
LL041_RS08985	COG0070	glutamate synthase
LL041_RS08995	COG1397	ADP-ribosylglycohydrolase
LL041_RS09015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL041_RS09020	COG2301	Belongs to the HpcH HpaI aldolase family
LL041_RS09025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LL041_RS09035	COG0159	tryptophan synthase activity
LL041_RS09040	COG0133	tryptophan synthase activity
LL041_RS09045	COG0134	indole-3-glycerol-phosphate synthase activity
LL041_RS09065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LL041_RS09070	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LL041_RS09085	COG0107	imidazoleglycerol-phosphate synthase activity
LL041_RS09090	COG0251	oxidation-reduction process
LL041_RS09095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LL041_RS09100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LL041_RS09110	COG0131	Imidazoleglycerol-phosphate dehydratase
LL041_RS09115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LL041_RS09120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LL041_RS09145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LL041_RS09165	COG1432	Conserved Protein
LL041_RS09180	COG0587	DNA-directed DNA polymerase activity
LL041_RS09240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LL041_RS09250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LL041_RS09255	COG3599	regulation of cell shape
LL041_RS09265	COG1799	cell septum assembly
LL041_RS09275	COG1496	oxidoreductase activity
LL041_RS09280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LL041_RS09285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LL041_RS09290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LL041_RS09300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LL041_RS09305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LL041_RS09315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LL041_RS09330	COG0275	rRNA processing
LL041_RS09340	COG0714	Associated with various cellular activities
LL041_RS09370	COG1129	ABC transporter
LL041_RS09380	COG1309	transcriptional regulator
LL041_RS09400	COG0352	thiamine-phosphate diphosphorylase activity
LL041_RS09420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LL041_RS09420	COG2022	thiamine diphosphate biosynthetic process
LL041_RS09430	COG2022	thiamine diphosphate biosynthetic process
LL041_RS09435	COG0515	serine threonine protein kinase
LL041_RS09435	COG2815	serine threonine protein kinase
LL041_RS09440	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LL041_RS09445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LL041_RS09450	COG2193	ferroxidase activity
LL041_RS09460	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LL041_RS09470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL041_RS09480	COG4585	Histidine kinase
LL041_RS09505	COG1940	carbohydrate kinase activity
LL041_RS09515	COG0003	Pfam Anion-transporting ATPase
LL041_RS09555	COG3103	Sh3 type 3 domain protein
LL041_RS09555	COG1388	LysM domain
LL041_RS09555	COG0791	NLP P60 protein
LL041_RS09580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LL041_RS09585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LL041_RS09590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LL041_RS09595	COG0723	plastoquinol--plastocyanin reductase activity
LL041_RS09600	COG2010	Cytochrome c
LL041_RS09605	COG1845	cytochrome c oxidase, subunit III
LL041_RS09615	COG1376	ErfK ybiS ycfS ynhG family protein
LL041_RS09625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LL041_RS09630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LL041_RS09640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL041_RS09660	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LL041_RS09665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LL041_RS09670	COG2197	response regulator
LL041_RS09715	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LL041_RS09725	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LL041_RS09740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LL041_RS09745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LL041_RS09750	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL041_RS09760	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LL041_RS09810	COG0321	lipoyl(octanoyl) transferase activity
LL041_RS09815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LL041_RS09835	COG0174	glutamine synthetase
LL041_RS09845	COG0501	Belongs to the peptidase M48B family
LL041_RS09875	COG0745	RESPONSE REGULATOR receiver
LL041_RS09890	COG2197	response regulator
LL041_RS09915	COG1309	transcriptional regulator
LL041_RS09940	COG0366	Alpha amylase catalytic
LL041_RS09945	COG3833	ABC-type maltose transport systems, permease component
LL041_RS09950	COG1175	transmembrane transport
LL041_RS09955	COG1653	transport
LL041_RS09960	COG1609	Transcriptional regulator
LL041_RS09970	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LL041_RS09995	COG0174	glutamine synthetase
LL041_RS10000	COG1959	2 iron, 2 sulfur cluster binding
LL041_RS10015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LL041_RS10015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LL041_RS10030	COG0477	Major facilitator Superfamily
LL041_RS10035	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LL041_RS10055	COG1994	Peptidase M50
LL041_RS10100	COG2837	iron assimilation
LL041_RS10105	COG0672	)-iron permease
LL041_RS10120	COG0584	glycerophosphoryl diester phosphodiesterase
LL041_RS10125	COG1309	transcriptional regulator
LL041_RS10140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LL041_RS10145	COG2814	Major facilitator Superfamily
LL041_RS10165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL041_RS10170	COG1414	Transcriptional regulator
LL041_RS10180	COG2409	Drug exporters of the RND superfamily
LL041_RS10185	COG0142	geranyltranstransferase activity
LL041_RS10215	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS10220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LL041_RS10225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LL041_RS10230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS10245	COG0183	Belongs to the thiolase family
LL041_RS10250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL041_RS10255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS10285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS10290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS10305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS10315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS10315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS10320	COG2124	cytochrome p450
LL041_RS10335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LL041_RS10355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS10360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL041_RS10395	COG1652	LysM domain
LL041_RS10405	COG0515	serine threonine protein kinase
LL041_RS10405	COG2815	serine threonine protein kinase
LL041_RS10410	COG1111	helicase
LL041_RS10410	COG1205	dead DEAH box helicase
LL041_RS10420	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LL041_RS10435	COG1476	TRANSCRIPTIONal
LL041_RS10455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LL041_RS10470	COG2124	cytochrome p450
LL041_RS10475	COG2124	cytochrome p450
LL041_RS10525	COG3022	response to hydroperoxide
LL041_RS10530	COG0800	Aldolase
LL041_RS10545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LL041_RS10560	COG2030	dehydratase
LL041_RS10565	COG4585	Histidine kinase
LL041_RS10570	COG2197	response regulator
LL041_RS10580	COG0477	Major facilitator Superfamily
LL041_RS10615	COG0438	transferase activity, transferring glycosyl groups
LL041_RS10620	COG1309	transcriptional regulator
LL041_RS10645	COG3845	ABC transporter
LL041_RS10670	COG4122	O-methyltransferase activity
LL041_RS10710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL041_RS10770	COG0586	Pfam SNARE associated Golgi protein
LL041_RS10780	COG1358	cellular component organization or biogenesis
LL041_RS10825	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LL041_RS10835	COG0477	Major facilitator Superfamily
LL041_RS10840	COG1309	transcriptional regulator
LL041_RS10855	COG0789	Transcriptional regulator
LL041_RS10905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL041_RS10910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL041_RS10915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL041_RS10940	COG1280	lysine exporter protein (LysE YggA)
LL041_RS10950	COG2130	NADP-dependent
LL041_RS10980	COG4213	ABC transporter substrate-binding protein
LL041_RS10990	COG4214	carbohydrate transport
LL041_RS11000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LL041_RS11005	COG3507	Belongs to the glycosyl hydrolase 43 family
LL041_RS11040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LL041_RS11065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LL041_RS11110	COG0395	ABC-type sugar transport system, permease component
LL041_RS11115	COG1175	transmembrane transport
LL041_RS11145	COG3386	PFAM SMP-30 Gluconolaconase
LL041_RS11150	COG1414	Transcriptional regulator
LL041_RS11170	COG2186	Transcriptional regulator
LL041_RS11180	COG0318	PFAM AMP-dependent synthetase and ligase
LL041_RS11185	COG0825	malonyl-CoA metabolic process
LL041_RS11185	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LL041_RS11190	COG1077	Cell shape determining protein MreB Mrl
LL041_RS11235	COG1070	Carbohydrate kinase
LL041_RS11250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LL041_RS11255	COG0358	DNA primase activity
LL041_RS11265	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LL041_RS11275	COG2949	membrane
LL041_RS11280	COG0243	molybdopterin cofactor binding
LL041_RS11305	COG1733	regulation of RNA biosynthetic process
LL041_RS11325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LL041_RS11325	COG2146	nitrite reductase [NAD(P)H] activity
LL041_RS11330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LL041_RS11330	COG2146	nitrite reductase [NAD(P)H] activity
LL041_RS11350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LL041_RS11350	COG0574	Belongs to the PEP-utilizing enzyme family
LL041_RS11375	COG0423	glycine-tRNA ligase activity
LL041_RS11380	COG0803	Belongs to the bacterial solute-binding protein 9 family
LL041_RS11380	COG3443	Belongs to the bacterial solute-binding protein 9 family
LL041_RS11385	COG1120	ATPase activity
LL041_RS11390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LL041_RS11405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LL041_RS11410	COG1381	Involved in DNA repair and RecF pathway recombination
LL041_RS11445	COG2197	response regulator
LL041_RS11450	COG4585	Histidine kinase
LL041_RS11455	COG2409	Drug exporters of the RND superfamily
LL041_RS11500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LL041_RS11520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LL041_RS11530	COG2315	Protein conserved in bacteria
LL041_RS11540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LL041_RS11550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL041_RS11555	COG4948	Mandelate Racemase Muconate Lactonizing
LL041_RS11560	COG1414	Transcriptional regulator
LL041_RS11570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LL041_RS11575	COG1234	tRNA 3'-trailer cleavage
LL041_RS11580	COG0537	adenosine 5'-monophosphoramidase activity
LL041_RS11585	COG0793	Belongs to the peptidase S41A family
LL041_RS11585	COG4946	Tricorn protease homolog
LL041_RS11605	COG0484	heat shock protein binding
LL041_RS11610	COG1420	regulation of RNA biosynthetic process
LL041_RS11640	COG0481	GTPase activity
LL041_RS11645	COG0268	Binds directly to 16S ribosomal RNA
LL041_RS11675	COG1307	EDD domain protein, DegV family
LL041_RS11685	COG0495	leucyl-tRNA aminoacylation
LL041_RS11695	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LL041_RS11720	COG0588	phosphoglycerate mutase activity
LL041_RS11725	COG0799	negative regulation of ribosome biogenesis
LL041_RS11735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LL041_RS11745	COG0501	Belongs to the peptidase M48B family
LL041_RS11760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LL041_RS11770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LL041_RS11785	COG1215	transferase activity, transferring glycosyl groups
LL041_RS11800	COG3540	Alkaline phosphatase
LL041_RS11810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LL041_RS11815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LL041_RS11820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LL041_RS11845	COG1530	ribonuclease E activity
LL041_RS11875	COG0772	Belongs to the SEDS family
LL041_RS11880	COG0768	penicillin binding
LL041_RS11895	COG1077	Cell shape determining protein MreB Mrl
LL041_RS11900	COG0105	UTP biosynthetic process
LL041_RS11910	COG0285	dihydrofolate synthase activity
LL041_RS11920	COG0525	valine-tRNA ligase activity
LL041_RS11930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LL041_RS11935	COG0740	serine-type endopeptidase activity
LL041_RS11940	COG0740	serine-type endopeptidase activity
LL041_RS11945	COG0544	peptidyl-prolyl cis-trans isomerase activity
LL041_RS11965	COG3594	Acyltransferase
LL041_RS11980	COG4552	Acetyltransferase involved in intracellular survival and related
LL041_RS11995	COG1113	amino acid transport
LL041_RS12005	COG1113	amino acid transport
LL041_RS12015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LL041_RS12075	COG1309	transcriptional regulator
LL041_RS12085	COG0697	spore germination
LL041_RS12090	COG1846	Transcriptional regulator
LL041_RS12110	COG3291	Pkd domain containing protein
LL041_RS12110	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LL041_RS12120	COG1136	(ABC) transporter
LL041_RS12135	COG0668	transmembrane transport
LL041_RS12145	COG1486	melibiose metabolic process
LL041_RS12190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LL041_RS12210	COG1136	(ABC) transporter
LL041_RS12250	COG0629	single-stranded DNA binding
LL041_RS12300	COG2304	oxidoreductase activity
LL041_RS12330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LL041_RS12340	COG0728	peptidoglycan biosynthetic process
LL041_RS12350	COG0438	transferase activity, transferring glycosyl groups
LL041_RS12365	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LL041_RS12370	COG0492	ferredoxin-NADP+ reductase activity
LL041_RS12385	COG1131	(ABC) transporter
LL041_RS12420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LL041_RS12465	COG1609	Transcriptional regulator
LL041_RS12470	COG1129	ABC transporter
LL041_RS12480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL041_RS12485	COG1869	D-ribose catabolic process
LL041_RS12500	COG0673	inositol 2-dehydrogenase activity
LL041_RS12505	COG1609	Transcriptional regulator
LL041_RS12520	COG0697	spore germination
LL041_RS12530	COG1472	Belongs to the glycosyl hydrolase 3 family
LL041_RS12560	COG2356	endonuclease I
LL041_RS12570	COG0028	Belongs to the TPP enzyme family
LL041_RS12590	COG1946	Acyl-CoA thioesterase
LL041_RS12600	COG1309	transcriptional regulator
LL041_RS12605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL041_RS12620	COG1960	acyl-CoA dehydrogenase activity
LL041_RS12635	COG3409	Peptidoglycan-binding domain 1 protein
LL041_RS12660	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LL041_RS12685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LL041_RS12690	COG0589	response to stress
LL041_RS12695	COG4977	sequence-specific DNA binding
LL041_RS12700	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LL041_RS12725	COG0395	ABC-type sugar transport system, permease component
LL041_RS12735	COG3979	chitinase
LL041_RS12745	COG0745	RESPONSE REGULATOR receiver
LL041_RS12755	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LL041_RS12770	COG0406	alpha-ribazole phosphatase activity
LL041_RS12820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL041_RS12835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL041_RS12850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL041_RS12855	COG0765	amino acid transport
LL041_RS12860	COG0765	amino acid transport
LL041_RS12865	COG1126	abc transporter atp-binding protein
LL041_RS12875	COG3397	chitin binding
LL041_RS12920	COG1940	carbohydrate kinase activity
LL041_RS12925	COG0673	inositol 2-dehydrogenase activity
LL041_RS12930	COG4702	Belongs to the UPF0303 family
LL041_RS12940	COG0706	membrane insertase activity
LL041_RS12965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LL041_RS13025	COG3467	pyridoxamine 5'-phosphate
LL041_RS13030	COG1309	transcriptional regulator
LL041_RS13035	COG4106	trans-aconitate 2-methyltransferase activity
LL041_RS13040	COG3226	Transcriptional regulator
LL041_RS13070	COG2271	Major facilitator Superfamily
LL041_RS13075	COG2733	membrane
LL041_RS13090	COG4555	ABC transporter
LL041_RS13105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL041_RS13145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LL041_RS13155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LL041_RS13160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL041_RS13165	COG1263	PTS System
LL041_RS13170	COG1263	PTS System
LL041_RS13175	COG1234	tRNA 3'-trailer cleavage
LL041_RS13200	COG1113	amino acid transport
LL041_RS13210	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LL041_RS13220	COG1335	isochorismatase
LL041_RS13250	COG0277	FAD linked oxidase domain protein
LL041_RS13260	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LL041_RS13270	COG1174	glycine betaine transport
LL041_RS13280	COG1174	glycine betaine transport
LL041_RS13285	COG1732	Glycine betaine
LL041_RS13300	COG1061	Type III restriction enzyme res subunit
LL041_RS13305	COG3654	unkown
LL041_RS13335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL041_RS13350	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LL041_RS13355	COG0395	ABC-type sugar transport system, permease component
LL041_RS13375	COG1678	Uncharacterized ACR, COG1678
LL041_RS13380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LL041_RS13385	COG0776	regulation of translation
LL041_RS13395	COG3973	AAA domain
LL041_RS13420	COG2223	nitrite transmembrane transporter activity
LL041_RS13485	COG0583	DNA-binding transcription factor activity
LL041_RS13495	COG1609	Transcriptional regulator
LL041_RS13510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LL041_RS13515	COG0793	Belongs to the peptidase S41A family
LL041_RS13525	COG2884	Cell division ATP-binding protein ftsE
LL041_RS13540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LL041_RS13545	COG0515	serine threonine protein kinase
LL041_RS13550	COG0515	serine threonine protein kinase
LL041_RS13565	COG1175	transmembrane transport
LL041_RS13570	COG0395	ABC-type sugar transport system, permease component
LL041_RS13575	COG0463	Glycosyl transferase, family 2
LL041_RS13575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL041_RS13580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL041_RS13585	COG1216	Glycosyl transferase, family 2
LL041_RS13600	COG1764	response to oxidative stress
LL041_RS13605	COG1846	Transcriptional regulator
LL041_RS13610	COG1215	transferase activity, transferring glycosyl groups
LL041_RS13630	COG1388	LysM domain
LL041_RS13630	COG1134	teichoic acid transport
LL041_RS13635	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL041_RS13640	COG1215	transferase activity, transferring glycosyl groups
LL041_RS13650	COG2902	Dehydrogenase
LL041_RS13670	COG0653	protein targeting
LL041_RS13680	COG3214	Protein conserved in bacteria
LL041_RS13685	COG2197	response regulator
LL041_RS13690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LL041_RS13700	COG0823	Involved in the tonB-independent uptake of proteins
LL041_RS13705	COG5002	protein histidine kinase activity
LL041_RS13710	COG0745	RESPONSE REGULATOR receiver
LL041_RS13715	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LL041_RS13735	COG0714	Associated with various cellular activities
LL041_RS13775	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LL041_RS13785	COG1482	cell wall glycoprotein biosynthetic process
LL041_RS13795	COG2835	tetraacyldisaccharide 4'-kinase activity
LL041_RS13800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LL041_RS13805	COG1620	l-lactate permease
LL041_RS13840	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LL041_RS13845	COG0778	Nitroreductase
LL041_RS13845	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LL041_RS13870	COG1316	TRANSCRIPTIONal
LL041_RS13875	COG1316	TRANSCRIPTIONal
LL041_RS13880	COG1316	TRANSCRIPTIONal
LL041_RS13885	COG1316	TRANSCRIPTIONal
LL041_RS13895	COG1316	TRANSCRIPTIONal
LL041_RS13905	COG1316	TRANSCRIPTIONal
LL041_RS13915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LL041_RS13925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LL041_RS13955	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LL041_RS13970	COG2205	protein histidine kinase activity
LL041_RS13975	COG0745	RESPONSE REGULATOR receiver
LL041_RS13980	COG3104	oligopeptide transport
LL041_RS13990	COG1366	Belongs to the anti-sigma-factor antagonist family
LL041_RS13995	COG1191	sigma factor activity
LL041_RS14000	COG1228	amidohydrolase
LL041_RS14015	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LL041_RS14050	COG2755	lipolytic protein G-D-S-L family
LL041_RS14055	COG0183	Belongs to the thiolase family
LL041_RS14090	COG1136	(ABC) transporter
LL041_RS14090	COG0577	efflux transmembrane transporter activity
LL041_RS14095	COG0577	efflux transmembrane transporter activity
LL041_RS14100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LL041_RS14105	COG1252	NADH dehydrogenase
LL041_RS14125	COG0148	phosphopyruvate hydratase activity
LL041_RS14200	COG0577	efflux transmembrane transporter activity
LL041_RS14205	COG1136	(ABC) transporter
LL041_RS14235	COG4585	Histidine kinase
LL041_RS14250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LL041_RS14255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LL041_RS14260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LL041_RS14265	COG0193	aminoacyl-tRNA hydrolase activity
LL041_RS14275	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LL041_RS14285	COG1309	transcriptional regulator
LL041_RS14290	COG4106	trans-aconitate 2-methyltransferase activity
LL041_RS14300	COG2197	response regulator
LL041_RS14310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LL041_RS14350	COG0488	(ABC) transporter
LL041_RS14355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LL041_RS14360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LL041_RS14365	COG0084	hydrolase, TatD family'
LL041_RS14405	COG0310	cobalt ion transport
LL041_RS14415	COG1122	ATPase activity
LL041_RS14420	COG1846	Transcriptional regulator
LL041_RS14425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LL041_RS14450	COG2409	Drug exporters of the RND superfamily
LL041_RS14460	COG0793	Belongs to the peptidase S41A family
LL041_RS14460	COG4946	Tricorn protease homolog
LL041_RS14475	COG2267	carboxylic ester hydrolase activity
LL041_RS14480	COG2072	flavoprotein involved in K transport
LL041_RS14495	COG0708	Exodeoxyribonuclease III
LL041_RS14535	COG0315	cyclic pyranopterin monophosphate synthase activity
LL041_RS14535	COG0521	Mo-molybdopterin cofactor biosynthetic process
LL041_RS14540	COG0315	cyclic pyranopterin monophosphate synthase activity
LL041_RS14550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LL041_RS14555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LL041_RS14580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LL041_RS14615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL041_RS14615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LL041_RS14615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LL041_RS14625	COG1349	DNA-binding transcription factor activity
LL041_RS14630	COG0477	Major facilitator Superfamily
LL041_RS14650	COG1247	-acetyltransferase
LL041_RS14655	COG3384	dioxygenase
LL041_RS14660	COG1846	Transcriptional regulator
LL041_RS14685	COG0582	viral genome integration into host DNA
LL041_RS14750	COG2801	Transposase and inactivated derivatives
LL041_RS14750	COG3415	Transposase
LL041_RS14770	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LL041_RS14780	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LL041_RS14785	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LL041_RS14830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LL041_RS14850	COG0076	glutamate decarboxylase activity
LL041_RS14930	COG0386	Belongs to the glutathione peroxidase family
LL041_RS14955	COG1686	Belongs to the peptidase S11 family
LL041_RS14980	COG0515	serine threonine protein kinase
LL041_RS14980	COG2815	serine threonine protein kinase
LL041_RS15000	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LL041_RS15020	COG3903	Transcriptional regulator
LL041_RS15020	COG3629	intracellular signal transduction
LL041_RS15035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LL041_RS15035	COG0515	serine threonine protein kinase
LL041_RS15045	COG1309	transcriptional regulator
LL041_RS15055	COG0259	pyridoxamine-phosphate oxidase activity
LL041_RS15065	COG2072	flavoprotein involved in K transport
LL041_RS15070	COG2271	Major facilitator Superfamily
LL041_RS15145	COG2945	thiolester hydrolase activity
LL041_RS15145	COG0596	Alpha beta hydrolase
LL041_RS15155	COG4821	SIS domain
LL041_RS15170	COG2252	PERMEase
LL041_RS15180	COG0259	pyridoxamine-phosphate oxidase activity
LL041_RS15195	COG0318	PFAM AMP-dependent synthetase and ligase
LL041_RS15210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL041_RS15235	COG5006	permease, DMT superfamily
LL041_RS15245	COG0277	FAD linked oxidase domain protein
LL041_RS15245	COG0247	lactate metabolic process
LL041_RS15280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LL041_RS15315	COG0667	Aldo Keto reductase
LL041_RS15345	COG2252	PERMEase
LL041_RS15355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LL041_RS15365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LL041_RS15365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LL041_RS15385	COG0739	heme binding
LL041_RS15420	COG2814	Major facilitator Superfamily
LL041_RS15430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LL041_RS15435	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LL041_RS15465	COG1061	Type III restriction enzyme res subunit
LL041_RS15475	COG3973	AAA domain
LL041_RS15490	COG1404	Belongs to the peptidase S8 family
LL041_RS15515	COG1737	Transcriptional regulator
LL041_RS15520	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LL041_RS15545	COG0459	protein refolding
LL041_RS15550	COG1278	Cold shock
LL041_RS15565	COG0463	Glycosyl transferase, family 2
LL041_RS15590	COG1940	carbohydrate kinase activity
LL041_RS15610	COG3300	MHYT domain
LL041_RS15610	COG5001	Diguanylate cyclase
LL041_RS15625	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LL041_RS15675	COG2378	regulation of single-species biofilm formation
LL041_RS15680	COG3842	ATPase activity
LL041_RS15705	COG0215	cysteine-tRNA ligase activity
LL041_RS15710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LL041_RS15715	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LL041_RS15720	COG1329	Transcriptional regulator
LL041_RS15735	COG5002	protein histidine kinase activity
LL041_RS15755	COG0588	phosphoglycerate mutase activity
LL041_RS15770	COG1396	sequence-specific DNA binding
LL041_RS15775	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LL041_RS15850	COG0438	transferase activity, transferring glycosyl groups
LL041_RS15895	COG2318	DinB family
LL041_RS15900	COG0395	ABC-type sugar transport system, permease component
LL041_RS15905	COG1175	transmembrane transport
LL041_RS15910	COG1653	transport
LL041_RS15915	COG0156	8-amino-7-oxononanoate synthase activity
LL041_RS15920	COG2186	Transcriptional regulator
LL041_RS15925	COG3973	AAA domain
LL041_RS15945	COG0546	phosphoglycolate phosphatase activity
LL041_RS15950	COG2188	Transcriptional regulator
LL041_RS15970	COG4552	Acetyltransferase involved in intracellular survival and related
LL041_RS15980	COG1490	D-aminoacyl-tRNA deacylase activity
LL041_RS15990	COG0735	belongs to the Fur family
LL041_RS15995	COG3485	protocatechuate 3,4-dioxygenase
LL041_RS16030	COG2897	thiosulfate sulfurtransferase activity
LL041_RS16055	COG0745	RESPONSE REGULATOR receiver
LL041_RS16060	COG1609	Transcriptional regulator
LL041_RS16065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL041_RS16080	COG3866	Pectate lyase
LL041_RS16115	COG0737	Belongs to the 5'-nucleotidase family
LL041_RS16120	COG0456	acetyltransferase
LL041_RS16155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LL041_RS16165	COG0494	nUDIX hydrolase
LL041_RS16165	COG0406	alpha-ribazole phosphatase activity
LL041_RS16185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LL041_RS16190	COG0306	phosphate transporter
LL041_RS16200	COG1937	Protein conserved in bacteria
LL041_RS16220	COG0671	phosphoesterase, PA-phosphatase related
LL041_RS16270	COG1131	(ABC) transporter
LL041_RS16280	COG4585	Histidine kinase
LL041_RS16285	COG2197	response regulator
LL041_RS16305	COG1846	Transcriptional regulator
LL041_RS16320	COG1252	NADH dehydrogenase
LL041_RS16340	COG0579	oxidoreductase
LL041_RS16345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LL041_RS16365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LL041_RS16365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LL041_RS16370	COG2197	response regulator
LL041_RS16390	COG0513	Belongs to the DEAD box helicase family
LL041_RS16425	COG1643	Atp-dependent helicase
LL041_RS16445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LL041_RS16455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LL041_RS16475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LL041_RS16480	COG0047	phosphoribosylformylglycinamidine synthase activity
LL041_RS16485	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LL041_RS16520	COG2197	response regulator
LL041_RS16530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LL041_RS16545	COG0151	Belongs to the GarS family
LL041_RS16605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LL041_RS16675	COG0438	transferase activity, transferring glycosyl groups
LL041_RS16680	COG0438	transferase activity, transferring glycosyl groups
LL041_RS16690	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS16725	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LL041_RS16835	COG1191	sigma factor activity
LL041_RS16840	COG1191	sigma factor activity
LL041_RS16855	COG0477	Major facilitator Superfamily
LL041_RS16875	COG3467	pyridoxamine 5'-phosphate
LL041_RS16880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LL041_RS16890	COG2205	protein histidine kinase activity
LL041_RS16895	COG0745	RESPONSE REGULATOR receiver
LL041_RS16915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LL041_RS16945	COG0784	Response regulator, receiver
LL041_RS16950	COG0318	PFAM AMP-dependent synthetase and ligase
LL041_RS16955	COG1595	DNA-templated transcription, initiation
LL041_RS16995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL041_RS17010	COG0653	protein targeting
LL041_RS17025	COG0006	proline dipeptidase activity
LL041_RS17045	COG1999	signal sequence binding
LL041_RS17060	COG2837	iron assimilation
LL041_RS17070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LL041_RS17075	COG0561	phosphatase activity
LL041_RS17105	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LL041_RS17120	COG0561	phosphatase activity
LL041_RS17130	COG4988	ABC transporter
LL041_RS17135	COG1294	oxidase, subunit
LL041_RS17140	COG1271	oxidase subunit
LL041_RS17145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LL041_RS17150	COG1609	Transcriptional regulator
LL041_RS17155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LL041_RS17170	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LL041_RS17195	COG0662	Cupin 2, conserved barrel domain protein
LL041_RS17200	COG1950	PFAM Membrane protein of
LL041_RS17205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LL041_RS17210	COG0626	cystathionine gamma-synthase activity
LL041_RS17235	COG2814	Major facilitator Superfamily
LL041_RS17260	COG0305	Participates in initiation and elongation during chromosome replication
LL041_RS17270	COG0359	binds to the 23S rRNA
LL041_RS17275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LL041_RS17280	COG0629	single-stranded DNA binding
LL041_RS17285	COG0360	Binds together with S18 to 16S ribosomal RNA
LL041_RS17310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL041_RS17320	COG1260	myo-inositol-1-phosphate synthase
LL041_RS17335	COG0617	tRNA 3'-terminal CCA addition
LL041_RS17355	COG1595	DNA-templated transcription, initiation
LL041_RS17365	COG0492	ferredoxin-NADP+ reductase activity
LL041_RS17370	COG3118	belongs to the thioredoxin family
LL041_RS17385	COG1192	Involved in chromosome partitioning
LL041_RS17390	COG0357	Ribosomal RNA small subunit methyltransferase G
LL041_RS17400	COG0706	membrane insertase activity
LL041_RS17405	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LL041_RS17410	COG0594	ribonuclease P activity
LL041_RS17415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LL041_RS17420	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LL041_RS17425	COG0592	DNA-directed DNA polymerase activity
LL041_RS17430	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LL041_RS17435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LL041_RS17440	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LL041_RS17445	COG0187	DNA topoisomerase II activity
LL041_RS17450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LL041_RS17485	COG0515	serine threonine protein kinase
LL041_RS17510	COG0705	Rhomboid family
LL041_RS17535	COG3764	Sortase (surface protein transpeptidase)
LL041_RS17540	COG3764	Sortase (surface protein transpeptidase)
LL041_RS17545	COG0515	serine threonine protein kinase
LL041_RS17550	COG0768	penicillin binding
LL041_RS17565	COG1716	ATPase activity
LL041_RS17570	COG1716	ATPase activity
LL041_RS17580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL041_RS17580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LL041_RS17595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL041_RS17600	COG1937	Protein conserved in bacteria
LL041_RS17610	COG1937	Protein conserved in bacteria
LL041_RS17625	COG1136	(ABC) transporter
LL041_RS17625	COG0577	efflux transmembrane transporter activity
LL041_RS17635	COG2197	response regulator
LL041_RS17670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LL041_RS17675	COG2151	metal-sulfur cluster biosynthetic enzyme
LL041_RS17680	COG3396	Phenylacetate-CoA oxygenase
LL041_RS17685	COG3460	Phenylacetate-CoA oxygenase
LL041_RS17690	COG3396	Phenylacetate-CoA oxygenase
LL041_RS17715	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS17720	COG1309	transcriptional regulator
LL041_RS17725	COG1522	sequence-specific DNA binding
LL041_RS17750	COG0303	'Molybdopterin
LL041_RS17770	COG0604	alcohol dehydrogenase
LL041_RS17770	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS17770	COG3321	synthase
LL041_RS17785	COG0515	serine threonine protein kinase
LL041_RS17790	COG0515	serine threonine protein kinase
LL041_RS17800	COG0022	dehydrogenase e1 component
LL041_RS17805	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL041_RS17850	COG1362	aminopeptidase activity
LL041_RS17855	COG1960	acyl-CoA dehydrogenase activity
LL041_RS17865	COG1741	Belongs to the pirin family
LL041_RS17875	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LL041_RS17895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL041_RS17910	COG0583	DNA-binding transcription factor activity
LL041_RS17965	COG0366	Alpha amylase catalytic
LL041_RS18000	COG1278	Cold shock
LL041_RS18010	COG0583	DNA-binding transcription factor activity
LL041_RS18020	COG2367	Beta-lactamase
LL041_RS18030	COG4213	ABC transporter substrate-binding protein
LL041_RS18040	COG2755	lipolytic protein G-D-S-L family
LL041_RS18040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LL041_RS18045	COG1595	DNA-templated transcription, initiation
LL041_RS18050	COG1252	NADH dehydrogenase
LL041_RS18065	COG1720	tRNA m6t6A37 methyltransferase activity
LL041_RS18075	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LL041_RS18115	COG0789	Transcriptional regulator
LL041_RS18120	COG1819	glycosyl
LL041_RS18130	COG3903	Transcriptional regulator
LL041_RS18130	COG3629	intracellular signal transduction
LL041_RS18160	COG0463	Glycosyl transferase, family 2
LL041_RS18185	COG0475	glutathione-regulated potassium exporter activity
LL041_RS18190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LL041_RS18220	COG2197	response regulator
LL041_RS18225	COG4585	Histidine kinase
LL041_RS18245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL041_RS18255	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
LL041_RS18420	COG0717	Belongs to the dCTP deaminase family
LL041_RS18425	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LL041_RS18445	COG0247	lactate metabolic process
LL041_RS18445	COG2181	nitrate reductase activity
LL041_RS18450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LL041_RS18455	COG0443	Heat shock 70 kDa protein
LL041_RS18460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LL041_RS18465	COG0484	heat shock protein binding
LL041_RS18470	COG0789	Transcriptional regulator
LL041_RS18475	COG4213	ABC transporter substrate-binding protein
LL041_RS18505	COG0542	response to heat
LL041_RS18540	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LL041_RS18550	COG2017	converts alpha-aldose to the beta-anomer
LL041_RS18555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LL041_RS18560	COG0191	fructose-bisphosphate aldolase activity
LL041_RS18565	COG0477	Major facilitator Superfamily
LL041_RS18580	COG3844	kynureninase activity
LL041_RS18600	COG4585	Histidine kinase
LL041_RS18605	COG2197	response regulator
LL041_RS18610	COG4585	Histidine kinase
LL041_RS18615	COG2197	response regulator
LL041_RS18625	COG3559	Exporter of polyketide antibiotics
LL041_RS18630	COG1131	(ABC) transporter
LL041_RS18650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LL041_RS18665	COG1802	Transcriptional regulator
LL041_RS18675	COG0693	protein deglycase activity
LL041_RS18690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LL041_RS18700	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LL041_RS18705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LL041_RS18715	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LL041_RS18720	COG1396	sequence-specific DNA binding
LL041_RS18765	COG0701	Predicted permease
LL041_RS18790	COG0604	alcohol dehydrogenase
LL041_RS18790	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS18790	COG3321	synthase
LL041_RS18805	COG3903	Transcriptional regulator
LL041_RS18805	COG3629	intracellular signal transduction
LL041_RS18930	COG0154	amidase activity
LL041_RS18960	COG2801	Transposase and inactivated derivatives
LL041_RS18960	COG3415	Transposase
LL041_RS18985	COG1408	metallophosphoesterase
LL041_RS19025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL041_RS19035	COG0003	Pfam Anion-transporting ATPase
LL041_RS19060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL041_RS19090	COG0596	Alpha beta hydrolase
LL041_RS19100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LL041_RS19105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LL041_RS19170	COG1111	helicase
LL041_RS19170	COG1205	dead DEAH box helicase
LL041_RS19175	COG1366	Belongs to the anti-sigma-factor antagonist family
LL041_RS19185	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LL041_RS19195	COG2264	protein methyltransferase activity
LL041_RS19205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LL041_RS19205	COG1754	DNA topoisomerase type I activity
LL041_RS19210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LL041_RS19245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL041_RS19245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL041_RS19285	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS19310	COG0789	Transcriptional regulator
LL041_RS19315	COG0586	Pfam SNARE associated Golgi protein
LL041_RS19325	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LL041_RS19330	COG2027	D-alanyl-D-alanine carboxypeptidase
LL041_RS19340	COG0037	tRNA processing
LL041_RS19355	COG0302	gtp cyclohydrolase
LL041_RS19370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LL041_RS19400	COG0649	NAD binding
LL041_RS19420	COG1660	Displays ATPase and GTPase activities
LL041_RS19440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LL041_RS19445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LL041_RS19455	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LL041_RS19475	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LL041_RS19500	COG0739	heme binding
LL041_RS19515	COG2205	protein histidine kinase activity
LL041_RS19520	COG0745	RESPONSE REGULATOR receiver
LL041_RS19530	COG1595	DNA-templated transcription, initiation
LL041_RS19535	COG1194	a g-specific adenine glycosylase
LL041_RS19560	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LL041_RS19580	COG0248	Ppx GppA phosphatase
LL041_RS19585	COG1082	Xylose isomerase domain protein TIM barrel
LL041_RS19590	COG1309	transcriptional regulator
LL041_RS19595	COG0129	dihydroxy-acid dehydratase activity
LL041_RS19620	COG1129	ABC transporter
LL041_RS19620	COG0842	Transport permease protein
LL041_RS19630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LL041_RS19645	COG0180	Tryptophanyl-tRNA synthetase
LL041_RS19675	COG0123	including yeast histone deacetylase and acetoin utilization protein
LL041_RS19730	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LL041_RS19735	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LL041_RS19740	COG0181	hydroxymethylbilane synthase activity
LL041_RS19745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LL041_RS19745	COG1648	precorrin-2 dehydrogenase activity
LL041_RS19780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LL041_RS19810	COG0113	porphobilinogen synthase activity
LL041_RS19825	COG0477	Major facilitator Superfamily
LL041_RS19825	COG2814	Major facilitator Superfamily
LL041_RS19835	COG2159	amidohydrolase
LL041_RS19840	COG0745	RESPONSE REGULATOR receiver
LL041_RS19845	COG2205	protein histidine kinase activity
LL041_RS19860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL041_RS19865	COG0018	arginyl-trna synthetase
LL041_RS19870	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LL041_RS19890	COG1690	Belongs to the RtcB family
LL041_RS19900	COG1742	UPF0060 membrane protein
LL041_RS19905	COG1846	Transcriptional regulator
LL041_RS19910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL041_RS19925	COG2205	protein histidine kinase activity
LL041_RS19930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL041_RS19935	COG2340	Cysteine-rich secretory protein family
LL041_RS19970	COG2197	response regulator
LL041_RS19975	COG4585	Histidine kinase
LL041_RS19990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LL041_RS19995	COG0406	alpha-ribazole phosphatase activity
LL041_RS20010	COG0785	Cytochrome C biogenesis protein
LL041_RS20015	COG1333	cytochrome c biogenesis protein
LL041_RS20020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LL041_RS20065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LL041_RS20070	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LL041_RS20080	COG0163	prenyltransferase activity
LL041_RS20090	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LL041_RS20105	COG1301	dicarboxylic acid transport
LL041_RS20135	COG1309	transcriptional regulator
LL041_RS20150	COG0183	Belongs to the thiolase family
LL041_RS20160	COG1278	Cold shock
LL041_RS20165	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LL041_RS20175	COG1674	ftsk spoiiie
LL041_RS20250	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LL041_RS20300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LL041_RS20310	COG3979	chitinase
LL041_RS20330	COG2226	methyltransferase
LL041_RS20360	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL041_RS20365	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL041_RS20370	COG0649	NAD binding
LL041_RS20380	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LL041_RS20385	COG1034	ATP synthesis coupled electron transport
LL041_RS20390	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LL041_RS20395	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL041_RS20400	COG0839	Belongs to the complex I subunit 6 family
LL041_RS20405	COG0713	ATP synthesis coupled electron transport
LL041_RS20410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LL041_RS20420	COG1007	ATP synthesis coupled electron transport
LL041_RS20425	COG0514	ATP-dependent DNA helicase (RecQ)
LL041_RS20480	COG0561	phosphatase activity
LL041_RS20490	COG0142	geranyltranstransferase activity
LL041_RS20500	COG1131	(ABC) transporter
LL041_RS20515	COG0655	NAD(P)H dehydrogenase (quinone) activity
LL041_RS20535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LL041_RS20565	COG3903	Transcriptional regulator
LL041_RS20565	COG3629	intracellular signal transduction
LL041_RS20570	COG0702	epimerase
LL041_RS20575	COG1733	regulation of RNA biosynthetic process
LL041_RS20580	COG1013	pyruvate-flavodoxin oxidoreductase activity
LL041_RS20585	COG0674	pyruvate-flavodoxin oxidoreductase activity
LL041_RS20585	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LL041_RS20605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL041_RS20610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL041_RS20615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL041_RS20620	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LL041_RS20625	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL041_RS20630	COG0839	Belongs to the complex I subunit 6 family
LL041_RS20635	COG0713	ATP synthesis coupled electron transport
LL041_RS20650	COG1007	ATP synthesis coupled electron transport
LL041_RS20655	COG0501	Belongs to the peptidase M48B family
LL041_RS20660	COG3304	Inner membrane component domain
LL041_RS20675	COG2261	transglycosylase associated protein
LL041_RS20680	COG1666	GTP binding
LL041_RS20780	COG0702	epimerase
LL041_RS20800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LL041_RS20805	COG2030	dehydratase
LL041_RS20815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LL041_RS20820	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LL041_RS20825	COG0436	Aminotransferase
LL041_RS20840	COG0250	Participates in transcription elongation, termination and antitermination
LL041_RS20845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LL041_RS20850	COG0081	regulation of translation
LL041_RS20860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LL041_RS20865	COG0222	ribosome binding
LL041_RS20870	COG0085	RNA polymerase activity
LL041_RS20875	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LL041_RS20885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LL041_RS20890	COG0049	tRNA binding
LL041_RS20895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LL041_RS20900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LL041_RS20925	COG0667	Aldo Keto reductase
LL041_RS20940	COG2197	response regulator
LL041_RS20945	COG4585	Histidine kinase
LL041_RS20950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LL041_RS20960	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS20995	COG0051	transcription antitermination factor activity, RNA binding
LL041_RS21000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LL041_RS21005	COG0088	Forms part of the polypeptide exit tunnel
LL041_RS21010	COG0089	rRNA binding
LL041_RS21015	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LL041_RS21020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LL041_RS21025	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LL041_RS21030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LL041_RS21035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LL041_RS21040	COG0255	Belongs to the universal ribosomal protein uL29 family
LL041_RS21045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LL041_RS21050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LL041_RS21055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LL041_RS21060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LL041_RS21065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LL041_RS21070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LL041_RS21075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LL041_RS21080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LL041_RS21085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LL041_RS21090	COG1841	ribosomal large subunit assembly
LL041_RS21095	COG0200	Binds to the 23S rRNA
LL041_RS21105	COG0563	adenylate kinase activity
LL041_RS21115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LL041_RS21120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LL041_RS21125	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LL041_RS21130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LL041_RS21135	COG0202	RNA polymerase activity
LL041_RS21140	COG0203	ribosomal protein L17
LL041_RS21145	COG0101	tRNA pseudouridine synthase activity
LL041_RS21155	COG2843	Capsule synthesis protein
LL041_RS21190	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LL041_RS21195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LL041_RS21200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LL041_RS21210	COG1072	(Pantothenic acid kinase))
LL041_RS21220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LL041_RS21225	COG0736	holo-[acyl-carrier-protein] synthase activity
LL041_RS21230	COG1191	sigma factor activity
LL041_RS21245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LL041_RS21255	COG0802	atpase or kinase
LL041_RS21280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LL041_RS21300	COG1609	Transcriptional regulator
LL041_RS21305	COG1316	TRANSCRIPTIONal
LL041_RS21315	COG4941	Belongs to the sigma-70 factor family
LL041_RS21325	COG0726	polysaccharide deacetylase
LL041_RS21330	COG0726	polysaccharide deacetylase
LL041_RS21335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LL041_RS21340	COG0459	protein refolding
LL041_RS21395	COG4221	oxidoreductase activity
LL041_RS21405	COG0583	DNA-binding transcription factor activity
LL041_RS21420	COG1595	DNA-templated transcription, initiation
LL041_RS21430	COG0516	GMP reductase activity
LL041_RS21440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LL041_RS21460	COG0515	serine threonine protein kinase
LL041_RS21465	COG0515	serine threonine protein kinase
LL041_RS21470	COG0515	serine threonine protein kinase
LL041_RS21475	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS21500	COG0519	Catalyzes the synthesis of GMP from XMP
LL041_RS21500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LL041_RS21540	COG2197	response regulator
LL041_RS21560	COG0739	heme binding
LL041_RS21570	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL041_RS21570	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL041_RS21585	COG0714	Associated with various cellular activities
LL041_RS21590	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LL041_RS21595	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LL041_RS21605	COG0045	succinate-CoA ligase (ADP-forming) activity
LL041_RS21635	COG0138	bifunctional purine biosynthesis protein purh
LL041_RS21655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LL041_RS21670	COG0039	L-malate dehydrogenase activity
LL041_RS21675	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS21685	COG0517	IMP dehydrogenase activity
LL041_RS21685	COG4175	Glycine betaine
LL041_RS21690	COG4176	ABC-type proline glycine betaine transport system permease component
LL041_RS21700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LL041_RS21710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL041_RS21720	COG0754	glutathionylspermidine amidase activity
LL041_RS21725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LL041_RS21735	COG0180	Tryptophanyl-tRNA synthetase
LL041_RS21755	COG0671	phosphoesterase, PA-phosphatase related
LL041_RS21770	COG1295	ribonuclease BN
LL041_RS21775	COG1686	Belongs to the peptidase S11 family
LL041_RS21785	COG1408	metallophosphoesterase
LL041_RS21790	COG1309	transcriptional regulator
LL041_RS21810	COG1053	succinate dehydrogenase
LL041_RS21820	COG2009	succinate dehydrogenase
LL041_RS21830	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LL041_RS21885	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL041_RS21885	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL041_RS21915	COG1216	Glycosyl transferase, family 2
LL041_RS21935	COG1216	Glycosyl transferase, family 2
LL041_RS21950	COG2089	acid synthase
LL041_RS21960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LL041_RS21960	COG1473	amidohydrolase
LL041_RS21965	COG1744	ABC transporter substrate-binding protein PnrA-like
LL041_RS21970	COG1744	ABC transporter substrate-binding protein PnrA-like
LL041_RS21975	COG3845	ABC transporter
LL041_RS21985	COG1079	Belongs to the binding-protein-dependent transport system permease family
LL041_RS22020	COG2814	Major facilitator Superfamily
LL041_RS22025	COG0583	DNA-binding transcription factor activity
LL041_RS22035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LL041_RS22060	COG2205	protein histidine kinase activity
LL041_RS22065	COG0745	RESPONSE REGULATOR receiver
LL041_RS22070	COG1595	DNA-templated transcription, initiation
LL041_RS22085	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS22090	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS22095	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LL041_RS22105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LL041_RS22130	COG4770	biotin carboxylase activity
LL041_RS22140	COG0424	maF-like protein
LL041_RS22150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL041_RS22160	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LL041_RS22170	COG1024	Enoyl-CoA hydratase
LL041_RS22180	COG2986	histidine ammonia-lyase
LL041_RS22205	COG1136	(ABC) transporter
LL041_RS22210	COG1404	Belongs to the peptidase S8 family
LL041_RS22220	COG1064	alcohol dehydrogenase
LL041_RS22230	COG0515	serine threonine protein kinase
LL041_RS22230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LL041_RS22255	COG2255	four-way junction helicase activity
LL041_RS22260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LL041_RS22275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LL041_RS22285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL041_RS22320	COG1331	Highly conserved protein containing a thioredoxin domain
LL041_RS22345	COG1331	Highly conserved protein containing a thioredoxin domain
LL041_RS22360	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LL041_RS22385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LL041_RS22485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LL041_RS22575	COG0436	Aminotransferase
LL041_RS22590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LL041_RS22605	COG1414	Transcriptional regulator
LL041_RS22610	COG0251	oxidation-reduction process
LL041_RS22615	COG2610	gluconate transmembrane transporter activity
LL041_RS22650	COG2894	cell division
LL041_RS22685	COG2197	response regulator
LL041_RS22750	COG2226	methyltransferase
LL041_RS22755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LL041_RS22775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LL041_RS22780	COG0450	alkyl hydroperoxide reductase
LL041_RS22795	COG1136	(ABC) transporter
LL041_RS22815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL041_RS22830	COG0114	fumarate hydratase activity
LL041_RS22865	COG2226	methyltransferase
LL041_RS22880	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LL041_RS22880	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LL041_RS22905	COG0778	Nitroreductase
LL041_RS22910	COG1722	exodeoxyribonuclease VII activity
LL041_RS22915	COG1570	exodeoxyribonuclease VII activity
LL041_RS22920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LL041_RS22925	COG1940	carbohydrate kinase activity
LL041_RS22935	COG0012	GTP binding
LL041_RS22965	COG1366	Belongs to the anti-sigma-factor antagonist family
LL041_RS22970	COG1366	Belongs to the anti-sigma-factor antagonist family
LL041_RS22975	COG2172	sigma factor antagonist activity
LL041_RS23050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LL041_RS23055	COG1053	succinate dehydrogenase
LL041_RS23075	COG1217	gtp-binding protein TYPA
LL041_RS23080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL041_RS23095	COG0444	Belongs to the ABC transporter superfamily
LL041_RS23100	COG4608	Belongs to the ABC transporter superfamily
LL041_RS23110	COG0601	transmembrane transport
LL041_RS23115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL041_RS23120	COG0444	Belongs to the ABC transporter superfamily
LL041_RS23125	COG4608	Belongs to the ABC transporter superfamily
LL041_RS23140	COG0154	amidase activity
LL041_RS23145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL041_RS23160	COG0477	Major facilitator Superfamily
LL041_RS23200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL041_RS23220	COG0519	Catalyzes the synthesis of GMP from XMP
LL041_RS23225	COG1024	Enoyl-CoA hydratase
LL041_RS23240	COG1595	DNA-templated transcription, initiation
LL041_RS23250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL041_RS23255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LL041_RS23290	COG0598	Magnesium transport protein CorA
LL041_RS23300	COG2814	Major facilitator Superfamily
LL041_RS23310	COG0613	PHP domain protein
LL041_RS23315	COG2095	MarC family integral membrane protein
LL041_RS23325	COG1432	Conserved Protein
LL041_RS23335	COG0513	Belongs to the DEAD box helicase family
LL041_RS23425	COG0210	DNA helicase
LL041_RS23430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL041_RS23435	COG2816	NAD+ diphosphatase activity
LL041_RS23470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LL041_RS23525	COG3480	Lon protease (S16) C-terminal proteolytic domain
LL041_RS23535	COG1615	UPF0182 protein
LL041_RS23560	COG0753	catalase activity
LL041_RS23570	COG0483	inositol monophosphate 1-phosphatase activity
LL041_RS23580	COG2076	Multidrug Resistance protein
LL041_RS23585	COG1162	GTPase activity
LL041_RS23590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LL041_RS23600	COG2135	peptidase activity
LL041_RS23610	COG1595	DNA-templated transcription, initiation
LL041_RS23615	COG5662	AntiSigma factor
LL041_RS23620	COG2199	diguanylate cyclase activity
LL041_RS23620	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LL041_RS23635	COG0242	peptide deformylase activity
LL041_RS23645	COG2124	cytochrome p450
LL041_RS23660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LL041_RS23685	COG2188	Transcriptional regulator
LL041_RS23690	COG0363	glucosamine-6-phosphate deaminase activity
LL041_RS23705	COG1597	lipid kinase activity
LL041_RS23750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LL041_RS23755	COG0142	geranyltranstransferase activity
LL041_RS23760	COG0456	acetyltransferase
LL041_RS23770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LL041_RS23820	COG4106	trans-aconitate 2-methyltransferase activity
LL041_RS23825	COG1126	abc transporter atp-binding protein
LL041_RS23840	COG0281	malic enzyme
LL041_RS23845	COG0604	alcohol dehydrogenase
LL041_RS23875	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL041_RS23875	COG0567	Dehydrogenase, E1 component
LL041_RS23880	COG2205	protein histidine kinase activity
LL041_RS23885	COG0745	RESPONSE REGULATOR receiver
LL041_RS23890	COG0275	rRNA processing
LL041_RS23895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LL041_RS23960	COG0768	penicillin binding
LL041_RS23965	COG0772	Belongs to the SEDS family
LL041_RS23985	COG1793	dna ligase
LL041_RS23985	COG3285	dna ligase
LL041_RS23990	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LL041_RS23995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL041_RS24010	COG1595	DNA-templated transcription, initiation
LL041_RS24025	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LL041_RS24060	COG1295	ribonuclease BN
LL041_RS24060	COG1959	2 iron, 2 sulfur cluster binding
LL041_RS24065	COG1366	Belongs to the anti-sigma-factor antagonist family
LL041_RS24220	COG3547	Transposase (IS116 IS110 IS902 family)
LL041_RS24235	COG2188	Transcriptional regulator
LL041_RS24245	COG2188	Transcriptional regulator
LL041_RS24315	COG0018	arginyl-trna synthetase
LL041_RS24320	COG0019	diaminopimelate decarboxylase activity
LL041_RS24325	COG0460	homoserine dehydrogenase
LL041_RS24330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LL041_RS24335	COG0083	homoserine kinase activity
LL041_RS24350	COG0254	rRNA binding
LL041_RS24355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LL041_RS24360	COG2890	protein-(glutamine-N5) methyltransferase activity
LL041_RS24370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LL041_RS24375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LL041_RS24380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LL041_RS24395	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LL041_RS24400	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LL041_RS24405	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LL041_RS24410	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LL041_RS24415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LL041_RS24420	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LL041_RS24425	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LL041_RS24440	COG2197	response regulator
LL041_RS24445	COG4585	Histidine kinase
LL041_RS24470	COG1309	transcriptional regulator
LL041_RS24480	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS24495	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LL041_RS24530	COG1131	(ABC) transporter
LL041_RS24550	COG0183	Belongs to the thiolase family
LL041_RS24565	COG0745	RESPONSE REGULATOR receiver
LL041_RS24620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL041_RS24620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL041_RS24660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LL041_RS24665	COG0857	belongs to the CobB CobQ family
LL041_RS24665	COG0280	phosphate acetyltransferase
LL041_RS24670	COG0205	6-phosphofructokinase activity
LL041_RS24680	COG0395	ABC-type sugar transport system, permease component
LL041_RS24685	COG1175	transmembrane transport
LL041_RS24690	COG1653	transport
LL041_RS24695	COG4565	transcriptional regulatory protein
LL041_RS24700	COG3290	protein histidine kinase activity
LL041_RS24705	COG1301	dicarboxylic acid transport
LL041_RS24710	COG0789	Transcriptional regulator
LL041_RS24725	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LL041_RS24730	COG3281	Trehalose synthase
LL041_RS24740	COG0366	Alpha amylase catalytic
LL041_RS24745	COG0058	SHG alpha-glucan phosphorylase activity
LL041_RS24765	COG1132	(ABC) transporter
LL041_RS24770	COG1132	(ABC) transporter
LL041_RS24775	COG1132	(ABC) transporter
LL041_RS24780	COG1132	(ABC) transporter
LL041_RS24785	COG1131	(ABC) transporter
LL041_RS24795	COG4585	Histidine kinase
LL041_RS24800	COG2197	response regulator
LL041_RS24885	COG0464	growth
LL041_RS24895	COG1674	ftsk spoiiie
LL041_RS24965	COG1760	l-serine dehydratase
LL041_RS24970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LL041_RS24975	COG0509	glycine decarboxylation via glycine cleavage system
LL041_RS24980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LL041_RS25000	COG0747	negative chemotaxis
LL041_RS25005	COG0601	transmembrane transport
LL041_RS25010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL041_RS25015	COG0444	Belongs to the ABC transporter superfamily
LL041_RS25020	COG4608	Belongs to the ABC transporter superfamily
LL041_RS25025	COG2860	membrane
LL041_RS25035	COG1309	transcriptional regulator
LL041_RS25065	COG0482	sulfurtransferase activity
LL041_RS25085	COG0475	glutathione-regulated potassium exporter activity
LL041_RS25095	COG2235	arginine
LL041_RS25100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LL041_RS25110	COG1024	Enoyl-CoA hydratase
LL041_RS25165	COG2755	lipolytic protein G-D-S-L family
LL041_RS25170	COG1122	ATPase activity
LL041_RS25180	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
LL041_RS25185	COG0310	cobalt ion transport
LL041_RS25195	COG0601	transmembrane transport
LL041_RS25200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL041_RS25205	COG0444	Belongs to the ABC transporter superfamily
LL041_RS25210	COG4608	Belongs to the ABC transporter superfamily
LL041_RS25225	COG1653	transport
LL041_RS25240	COG0515	serine threonine protein kinase
LL041_RS25305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL041_RS25315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LL041_RS25325	COG4257	antibiotic catabolic process
LL041_RS25330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LL041_RS25355	COG1653	transport
LL041_RS25360	COG1175	transmembrane transport
LL041_RS25365	COG0395	ABC-type sugar transport system, permease component
LL041_RS25370	COG1940	carbohydrate kinase activity
LL041_RS25375	COG4213	ABC transporter substrate-binding protein
LL041_RS25385	COG4214	carbohydrate transport
LL041_RS25390	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LL041_RS25395	COG0531	amino acid
LL041_RS25410	COG1316	TRANSCRIPTIONal
LL041_RS25415	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL041_RS25435	COG1024	Enoyl-CoA hydratase
LL041_RS25435	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS25440	COG0183	Belongs to the thiolase family
LL041_RS25445	COG1609	Transcriptional regulator
LL041_RS25450	COG3250	beta-galactosidase activity
LL041_RS25460	COG1175	transmembrane transport
LL041_RS25470	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LL041_RS25485	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LL041_RS25520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL041_RS25525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LL041_RS25550	COG1132	(ABC) transporter
LL041_RS25565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS25590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL041_RS25595	COG2197	response regulator
LL041_RS25600	COG4585	Histidine kinase
LL041_RS25620	COG0318	PFAM AMP-dependent synthetase and ligase
LL041_RS25640	COG0446	pyridine nucleotide-disulphide oxidoreductase
LL041_RS25650	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LL041_RS25655	COG3253	May function as heme-dependent peroxidase
LL041_RS25670	COG3220	belongs to the UPF0276 family
LL041_RS25695	COG0723	plastoquinol--plastocyanin reductase activity
LL041_RS25710	COG0330	HflC and HflK could
LL041_RS25715	COG0659	secondary active sulfate transmembrane transporter activity
LL041_RS25740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LL041_RS25745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LL041_RS25780	COG0745	RESPONSE REGULATOR receiver
LL041_RS25785	COG5002	protein histidine kinase activity
LL041_RS25795	COG2205	protein histidine kinase activity
LL041_RS25800	COG0745	RESPONSE REGULATOR receiver
LL041_RS25820	COG2186	Transcriptional regulator
LL041_RS25830	COG2376	Dihydroxyacetone kinase
LL041_RS25835	COG0698	ribose 5-phosphate isomerase
LL041_RS25840	COG0149	triose-phosphate isomerase activity
LL041_RS25845	COG1082	Xylose isomerase domain protein TIM barrel
LL041_RS25850	COG2084	Dehydrogenase
LL041_RS25860	COG1174	glycine betaine transport
LL041_RS25865	COG1174	glycine betaine transport
LL041_RS25905	COG1309	transcriptional regulator
LL041_RS25925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LL041_RS26010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LL041_RS26015	COG1116	anion transmembrane transporter activity
LL041_RS26040	COG0529	Catalyzes the synthesis of activated sulfate
LL041_RS26045	COG0175	sulfate reduction
LL041_RS26075	COG1960	acyl-CoA dehydrogenase activity
LL041_RS26090	COG1917	Cupin 2, conserved barrel domain protein
LL041_RS26090	COG4977	sequence-specific DNA binding
LL041_RS26150	COG2040	homocysteine
LL041_RS26160	COG0477	Major facilitator Superfamily
LL041_RS26205	COG2755	lipolytic protein G-D-S-L family
LL041_RS26260	COG0277	FAD linked oxidase domain protein
LL041_RS26270	COG5297	Belongs to the glycosyl hydrolase family 6
LL041_RS26275	COG1162	GTPase activity
LL041_RS26300	COG0028	Belongs to the TPP enzyme family
LL041_RS26330	COG1802	Transcriptional regulator
LL041_RS26340	COG3835	regulator
LL041_RS26355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL041_RS26380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LL041_RS26390	COG0438	transferase activity, transferring glycosyl groups
LL041_RS26400	COG1215	transferase activity, transferring glycosyl groups
LL041_RS26430	COG2197	response regulator
LL041_RS26435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LL041_RS26440	COG0318	PFAM AMP-dependent synthetase and ligase
LL041_RS26445	COG3960	tartronate-semialdehyde synthase activity
LL041_RS26460	COG2084	Dehydrogenase
LL041_RS26465	COG3622	Belongs to the hyi family
LL041_RS26485	COG2351	hydroxyisourate hydrolase activity
LL041_RS26570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL041_RS26620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LL041_RS26635	COG1414	Transcriptional regulator
LL041_RS26640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LL041_RS26645	COG4266	Belongs to the allantoicase family
LL041_RS26650	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS26670	COG2197	response regulator
LL041_RS26685	COG2188	Transcriptional regulator
LL041_RS26700	COG1129	ABC transporter
LL041_RS26705	COG1940	carbohydrate kinase activity
LL041_RS26715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LL041_RS26780	COG0142	geranyltranstransferase activity
LL041_RS26785	COG3046	protein related to deoxyribodipyrimidine photolyase
LL041_RS26795	COG0702	epimerase
LL041_RS26800	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS26805	COG1278	Cold shock
LL041_RS26810	COG0513	Belongs to the DEAD box helicase family
LL041_RS26820	COG1278	Cold shock
LL041_RS26825	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LL041_RS26830	COG1115	amino acid carrier protein
LL041_RS26850	COG1278	Cold shock
LL041_RS26870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LL041_RS26875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LL041_RS26895	COG0405	Gamma-glutamyltransferase
LL041_RS26900	COG0542	response to heat
LL041_RS26925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LL041_RS26930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LL041_RS26940	COG1953	Uracil, thiamine, allantoin
LL041_RS26960	COG4608	Belongs to the ABC transporter superfamily
LL041_RS26965	COG0444	Belongs to the ABC transporter superfamily
LL041_RS26975	COG4166	transmembrane transport
LL041_RS26985	COG3458	cephalosporin-C deacetylase activity
LL041_RS26995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL041_RS27005	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LL041_RS27015	COG0483	inositol monophosphate 1-phosphatase activity
LL041_RS27025	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LL041_RS27035	COG0640	Transcriptional regulator
LL041_RS27055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LL041_RS27065	COG1929	Belongs to the glycerate kinase type-1 family
LL041_RS27080	COG0688	phosphatidylethanolamine metabolic process
LL041_RS27085	COG1960	acyl-CoA dehydrogenase activity
LL041_RS27095	COG2301	Belongs to the HpcH HpaI aldolase family
LL041_RS27100	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL041_RS27100	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL041_RS27105	COG0604	alcohol dehydrogenase
LL041_RS27115	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS27130	COG0596	Alpha beta hydrolase
LL041_RS27150	COG2172	sigma factor antagonist activity
LL041_RS27150	COG2208	phosphoserine phosphatase activity
LL041_RS27150	COG1366	Belongs to the anti-sigma-factor antagonist family
LL041_RS27160	COG2362	D-Aminopeptidase
LL041_RS27165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL041_RS27170	COG0823	Involved in the tonB-independent uptake of proteins
LL041_RS27170	COG1506	peptidase
LL041_RS27170	COG4946	Tricorn protease homolog
LL041_RS27175	COG1619	proteins homologs of microcin C7 resistance protein MccF
LL041_RS27200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL041_RS27215	COG1793	dna ligase
LL041_RS27215	COG3285	dna ligase
LL041_RS27275	COG0488	(ABC) transporter
LL041_RS27290	COG0693	protein deglycase activity
LL041_RS27295	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LL041_RS27365	COG0443	Heat shock 70 kDa protein
LL041_RS27385	COG2154	pterin-4-alpha-carbinolamine dehydratase
LL041_RS27395	COG3401	FG-GAP repeat protein
LL041_RS27410	COG5297	Belongs to the glycosyl hydrolase family 6
LL041_RS27410	COG4733	cellulase activity
LL041_RS27415	COG5297	Belongs to the glycosyl hydrolase family 6
LL041_RS27425	COG4221	oxidoreductase activity
LL041_RS27430	COG0656	L-ascorbic acid biosynthetic process
LL041_RS27450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LL041_RS27465	COG3383	formate dehydrogenase (NAD+) activity
LL041_RS27470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LL041_RS27485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL041_RS27495	COG1940	carbohydrate kinase activity
LL041_RS27500	COG1129	ABC transporter
LL041_RS27505	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL041_RS27510	COG1879	ABC-type sugar transport system periplasmic component
LL041_RS27515	COG0673	inositol 2-dehydrogenase activity
LL041_RS27570	COG2223	nitrite transmembrane transporter activity
LL041_RS27580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL041_RS27590	COG0045	succinate-CoA ligase (ADP-forming) activity
LL041_RS27605	COG1611	Belongs to the LOG family
LL041_RS27610	COG4221	oxidoreductase activity
LL041_RS27620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LL041_RS27630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LL041_RS27635	COG0154	amidase activity
LL041_RS27645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LL041_RS27650	COG2226	methyltransferase
LL041_RS27660	COG2409	Drug exporters of the RND superfamily
LL041_RS27665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL041_RS27675	COG2197	response regulator
LL041_RS27685	COG2133	pyrroloquinoline quinone binding
LL041_RS27690	COG0667	Aldo Keto reductase
LL041_RS27700	COG5001	Diguanylate cyclase
LL041_RS27700	COG3300	MHYT domain
LL041_RS27710	COG0440	acetolactate synthase activity
LL041_RS27715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LL041_RS27720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LL041_RS27725	COG0477	Major facilitator Superfamily
LL041_RS27735	COG2508	Transcriptional regulator
LL041_RS27740	COG0506	proline dehydrogenase activity
LL041_RS27745	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS27750	COG0473	3-isopropylmalate dehydrogenase activity
LL041_RS27755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LL041_RS27760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LL041_RS27775	COG1032	radical SAM domain protein
LL041_RS27780	COG0300	oxidoreductase activity
LL041_RS27785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL041_RS27805	COG2018	Roadblock/LC7 domain
LL041_RS27825	COG2018	Roadblock/LC7 domain
LL041_RS27830	COG5002	protein histidine kinase activity
LL041_RS27840	COG0179	Fumarylacetoacetate (FAA) hydrolase
LL041_RS27845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LL041_RS27880	COG0789	Transcriptional regulator
LL041_RS27890	COG1414	Transcriptional regulator
LL041_RS27895	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LL041_RS27900	COG0066	3-isopropylmalate dehydratase activity
LL041_RS27910	COG0776	regulation of translation
LL041_RS27920	COG1920	GTP binding
LL041_RS27930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LL041_RS27935	COG1181	Belongs to the D-alanine--D-alanine ligase family
LL041_RS27955	COG0351	phosphomethylpyrimidine kinase
LL041_RS27960	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LL041_RS27965	COG1461	Dihydroxyacetone kinase
LL041_RS27975	COG0742	ribosomal rna small subunit methyltransferase
LL041_RS27980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LL041_RS27990	COG1399	metal-binding, possibly nucleic acid-binding protein
LL041_RS27995	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LL041_RS28000	COG0571	ribonuclease III activity
LL041_RS28005	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LL041_RS28010	COG1733	regulation of RNA biosynthetic process
LL041_RS28015	COG2340	Cysteine-rich secretory protein family
LL041_RS28020	COG1254	Belongs to the acylphosphatase family
LL041_RS28030	COG1196	nuclear chromosome segregation
LL041_RS28035	COG0477	Major facilitator Superfamily
LL041_RS28065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LL041_RS28085	COG0228	four-way junction DNA binding
LL041_RS28090	COG1837	Belongs to the UPF0109 family
LL041_RS28095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LL041_RS28100	COG0336	Belongs to the RNA methyltransferase TrmD family
LL041_RS28105	COG0335	large ribosomal subunit rRNA binding
LL041_RS28120	COG0681	Belongs to the peptidase S26 family
LL041_RS28125	COG0681	Belongs to the peptidase S26 family
LL041_RS28130	COG0494	nUDIX hydrolase
LL041_RS28140	COG0792	nuclease activity
LL041_RS28155	COG1191	sigma factor activity
LL041_RS28165	COG4942	peptidase
LL041_RS28170	COG0052	Belongs to the universal ribosomal protein uS2 family
LL041_RS28175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LL041_RS28180	COG0528	UMP kinase activity
LL041_RS28185	COG0233	cytoplasmic translational termination
LL041_RS28190	COG0575	Belongs to the CDS family
LL041_RS28200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LL041_RS28210	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LL041_RS28215	COG3842	ATPase activity
LL041_RS28245	COG1136	(ABC) transporter
LL041_RS28250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LL041_RS28260	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS28275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LL041_RS28305	COG3842	ATPase activity
LL041_RS28315	COG1177	transmembrane transport
LL041_RS28320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LL041_RS28340	COG2508	Transcriptional regulator
LL041_RS28345	COG1012	belongs to the aldehyde dehydrogenase family
LL041_RS28360	COG4209	transmembrane transport
LL041_RS28365	COG0395	ABC-type sugar transport system, permease component
LL041_RS28390	COG2197	response regulator
LL041_RS28395	COG4585	Histidine kinase
LL041_RS28405	COG1136	(ABC) transporter
LL041_RS28405	COG4591	ABC-type transport system involved in lipoprotein release permease component
LL041_RS28415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LL041_RS28420	COG0750	zinc metalloprotease
LL041_RS28425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LL041_RS28440	COG0442	prolyl-tRNA aminoacylation
LL041_RS28460	COG0779	Required for maturation of 30S ribosomal subunits
LL041_RS28475	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LL041_RS28485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LL041_RS28490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LL041_RS28505	COG4608	Belongs to the ABC transporter superfamily
LL041_RS28510	COG0444	Belongs to the ABC transporter superfamily
LL041_RS28520	COG0601	transmembrane transport
LL041_RS28525	COG0747	negative chemotaxis
LL041_RS28530	COG0455	bacterial-type flagellum organization
LL041_RS28540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LL041_RS28545	COG1185	polyribonucleotide nucleotidyltransferase activity
LL041_RS28550	COG0612	Peptidase, M16
LL041_RS28555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LL041_RS28575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL041_RS28580	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LL041_RS28610	COG2208	phosphoserine phosphatase activity
LL041_RS28610	COG2770	Histidine kinase
LL041_RS28615	COG0784	Response regulator, receiver
LL041_RS28615	COG2205	protein histidine kinase activity
LL041_RS28625	COG1674	ftsk spoiiie
LL041_RS28635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LL041_RS28645	COG1546	Belongs to the CinA family
LL041_RS28645	COG1058	Belongs to the CinA family
LL041_RS28650	COG1396	sequence-specific DNA binding
LL041_RS28655	COG0783	Belongs to the Dps family
LL041_RS28665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LL041_RS28670	COG1201	RNA secondary structure unwinding
LL041_RS28675	COG1917	Cupin 2, conserved barrel domain protein
LL041_RS28675	COG2207	Transcriptional regulator
LL041_RS28700	COG0628	permease
LL041_RS28705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LL041_RS28750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LL041_RS28755	COG0765	amino acid transport
LL041_RS28760	COG0765	amino acid transport
LL041_RS28765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL041_RS28770	COG1126	abc transporter atp-binding protein
LL041_RS28775	COG0745	RESPONSE REGULATOR receiver
LL041_RS28780	COG2205	protein histidine kinase activity
LL041_RS28785	COG2358	TRAP transporter, solute receptor (TAXI family
LL041_RS28800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LL041_RS28820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LL041_RS28830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LL041_RS28835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LL041_RS28840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LL041_RS28870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LL041_RS28875	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LL041_RS28880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LL041_RS28915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LL041_RS28950	COG1802	Transcriptional regulator
LL041_RS28955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LL041_RS28970	COG0187	DNA topoisomerase II activity
LL041_RS28980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL041_RS28985	COG4565	transcriptional regulatory protein
LL041_RS28990	COG3290	protein histidine kinase activity
LL041_RS29015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LL041_RS29020	COG0612	Peptidase, M16
LL041_RS29035	COG1802	Transcriptional regulator
LL041_RS29040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL041_RS29045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL041_RS29045	COG0045	succinate-CoA ligase (ADP-forming) activity
LL041_RS29045	COG1042	CoA-binding domain protein
LL041_RS29060	COG1435	thymidine kinase activity
LL041_RS29080	COG3864	Putative metallopeptidase domain
LL041_RS29135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LL041_RS29150	COG0745	RESPONSE REGULATOR receiver
LL041_RS29155	COG2205	protein histidine kinase activity
LL041_RS29180	COG0756	dUTP diphosphatase activity
LL041_RS29190	COG4591	ABC-type transport system involved in lipoprotein release permease component
LL041_RS29190	COG1136	(ABC) transporter
LL041_RS29220	COG0569	domain protein
LL041_RS29225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL041_RS29230	COG0531	amino acid
LL041_RS29235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LL041_RS29260	COG2409	Drug exporters of the RND superfamily
LL041_RS29290	COG3291	Pkd domain containing protein
LL041_RS29345	COG0659	secondary active sulfate transmembrane transporter activity
LL041_RS29350	COG0789	Transcriptional regulator
LL041_RS29360	COG0640	Transcriptional regulator
LL041_RS29365	COG2072	flavoprotein involved in K transport
LL041_RS29370	COG0798	PFAM Bile acid sodium symporter
LL041_RS29380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LL041_RS29390	COG0596	Alpha beta hydrolase
LL041_RS29415	COG3693	PFAM glycoside hydrolase, family 10
LL041_RS29420	COG1960	acyl-CoA dehydrogenase activity
LL041_RS29425	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL041_RS29430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LL041_RS29435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LL041_RS29440	COG0583	DNA-binding transcription factor activity
LL041_RS29445	COG0183	Belongs to the thiolase family
LL041_RS29450	COG0477	Major facilitator Superfamily
LL041_RS29465	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LL041_RS29470	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LL041_RS29480	COG1216	Glycosyl transferase, family 2
LL041_RS29490	COG4310	Domain of unknown function (DUF2172)
LL041_RS29505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LL041_RS29535	COG1063	alcohol dehydrogenase
LL041_RS29540	COG0367	asparagine synthase
LL041_RS29560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LL041_RS29580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL041_RS29585	COG0601	transmembrane transport
LL041_RS29590	COG4166	transmembrane transport
LL041_RS29605	COG4948	Mandelate Racemase Muconate Lactonizing
LL041_RS29610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LL041_RS29620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LL041_RS29630	COG2186	Transcriptional regulator
LL041_RS29635	COG1013	pyruvate-flavodoxin oxidoreductase activity
LL041_RS29640	COG0674	pyruvate-flavodoxin oxidoreductase activity
LL041_RS29640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LL041_RS29645	COG0175	sulfate reduction
LL041_RS29665	COG1116	anion transmembrane transporter activity
LL041_RS29690	COG2197	response regulator
LL041_RS29695	COG4585	Histidine kinase
LL041_RS29725	COG1960	acyl-CoA dehydrogenase activity
LL041_RS29735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL041_RS29735	COG2070	2-Nitropropane dioxygenase
LL041_RS29745	COG3321	synthase
LL041_RS29745	COG0604	alcohol dehydrogenase
LL041_RS29760	COG4566	intracellular signal transduction
LL041_RS29765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LL041_RS29780	COG1028	Short-chain dehydrogenase reductase Sdr
LL041_RS29785	COG0402	S-adenosylhomocysteine deaminase activity
LL041_RS29795	COG1021	2,3-dihydroxybenzoate-AMP ligase
LL041_RS29815	COG2375	cellular response to nickel ion
LL041_RS29815	COG1132	(ABC) transporter
LL041_RS29820	COG1132	(ABC) transporter
LL041_RS29825	COG1942	4-Oxalocrotonate Tautomerase
LL041_RS29870	COG1349	DNA-binding transcription factor activity
LL041_RS29875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LL041_RS29885	COG0667	Aldo Keto reductase
LL041_RS29900	COG1914	H( )-stimulated, divalent metal cation uptake system
LL041_RS29905	COG0738	Major facilitator superfamily
LL041_RS29930	COG2188	Transcriptional regulator
LL041_RS29935	COG2182	Extracellular solute-binding protein
LL041_RS29940	COG1175	transmembrane transport
LL041_RS29945	COG0395	ABC-type sugar transport system, permease component
LL041_RS29950	COG1472	Belongs to the glycosyl hydrolase 3 family
LL041_RS29960	COG1799	cell septum assembly
LL041_RS29990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LL041_RS30000	COG2255	four-way junction helicase activity
LL041_RS30010	COG0475	glutathione-regulated potassium exporter activity
LL041_RS30020	COG2235	arginine
LL041_RS30025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LL041_RS30035	COG1024	Enoyl-CoA hydratase
LL041_RS30170	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)