locus-tag	class	description
LL042_RS00240	COG2814	Major facilitator Superfamily
LL042_RS00255	COG0300	oxidoreductase activity
LL042_RS00260	COG3321	synthase
LL042_RS00265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL042_RS00270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS00275	COG1024	Enoyl-CoA hydratase
LL042_RS00280	COG1024	Enoyl-CoA hydratase
LL042_RS00285	COG3425	synthase
LL042_RS00290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL042_RS00295	COG2070	2-Nitropropane dioxygenase
LL042_RS00295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL042_RS00300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS00300	COG0300	oxidoreductase activity
LL042_RS00300	COG3321	synthase
LL042_RS00300	COG4221	oxidoreductase activity
LL042_RS00305	COG4221	oxidoreductase activity
LL042_RS00305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS00305	COG0300	oxidoreductase activity
LL042_RS00305	COG3321	synthase
LL042_RS00320	COG4221	oxidoreductase activity
LL042_RS00320	COG3321	synthase
LL042_RS00320	COG0300	oxidoreductase activity
LL042_RS00320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS00325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS00325	COG0300	oxidoreductase activity
LL042_RS00325	COG3321	synthase
LL042_RS00325	COG4221	oxidoreductase activity
LL042_RS00330	COG3321	synthase
LL042_RS00330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS00330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LL042_RS00330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS00330	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS00340	COG2124	cytochrome p450
LL042_RS00390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LL042_RS00390	COG0515	serine threonine protein kinase
LL042_RS00410	COG0667	Aldo Keto reductase
LL042_RS00435	COG0395	ABC-type sugar transport system, permease component
LL042_RS00535	COG0346	lactoylglutathione lyase activity
LL042_RS00540	COG0640	Transcriptional regulator
LL042_RS00555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL042_RS00590	COG0667	Aldo Keto reductase
LL042_RS00615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL042_RS00620	COG4948	Mandelate Racemase Muconate Lactonizing
LL042_RS00625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL042_RS00630	COG0747	negative chemotaxis
LL042_RS00635	COG0601	transmembrane transport
LL042_RS00640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL042_RS00645	COG0444	Belongs to the ABC transporter superfamily
LL042_RS00650	COG4608	Belongs to the ABC transporter superfamily
LL042_RS00715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL042_RS00720	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL042_RS00730	COG1129	ABC transporter
LL042_RS00735	COG1869	D-ribose catabolic process
LL042_RS00740	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LL042_RS00745	COG2188	Transcriptional regulator
LL042_RS00755	COG1733	regulation of RNA biosynthetic process
LL042_RS00780	COG0596	Alpha beta hydrolase
LL042_RS00795	COG0531	amino acid
LL042_RS00810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL042_RS00815	COG1309	transcriptional regulator
LL042_RS00835	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL042_RS00840	COG0183	Belongs to the thiolase family
LL042_RS00850	COG0604	alcohol dehydrogenase
LL042_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS00850	COG3321	synthase
LL042_RS00855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL042_RS00860	COG1021	2,3-dihydroxybenzoate-AMP ligase
LL042_RS00870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LL042_RS00875	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL042_RS00880	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL042_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS00890	COG1960	acyl-CoA dehydrogenase activity
LL042_RS00895	COG1024	Enoyl-CoA hydratase
LL042_RS00905	COG0477	Major facilitator Superfamily
LL042_RS00915	COG2815	serine threonine protein kinase
LL042_RS00915	COG0515	serine threonine protein kinase
LL042_RS00925	COG0514	ATP-dependent DNA helicase (RecQ)
LL042_RS00960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LL042_RS00990	COG3321	synthase
LL042_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS00990	COG0604	alcohol dehydrogenase
LL042_RS01015	COG0477	Major facilitator Superfamily
LL042_RS01025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LL042_RS01025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LL042_RS01055	COG2755	lipolytic protein G-D-S-L family
LL042_RS01085	COG0456	acetyltransferase
LL042_RS01090	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LL042_RS01105	COG0583	DNA-binding transcription factor activity
LL042_RS01115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LL042_RS01135	COG1891	lyase activity
LL042_RS01150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LL042_RS01155	COG1022	Amp-dependent synthetase and ligase
LL042_RS01165	COG0183	Belongs to the thiolase family
LL042_RS01175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL042_RS01180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL042_RS01200	COG1309	transcriptional regulator
LL042_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS01250	COG2378	regulation of single-species biofilm formation
LL042_RS01265	COG2045	Belongs to the ComB family
LL042_RS01340	COG0803	Belongs to the bacterial solute-binding protein 9 family
LL042_RS01350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LL042_RS01355	COG1120	ATPase activity
LL042_RS01365	COG1595	DNA-templated transcription, initiation
LL042_RS01370	COG0738	Major facilitator superfamily
LL042_RS01380	COG1120	ATPase activity
LL042_RS01385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL042_RS01405	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS01410	COG3844	kynureninase activity
LL042_RS01420	COG3483	tryptophan 2,3-dioxygenase activity
LL042_RS01425	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS01430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LL042_RS01435	COG2151	metal-sulfur cluster biosynthetic enzyme
LL042_RS01440	COG3396	Phenylacetate-CoA oxygenase
LL042_RS01450	COG3396	Phenylacetate-CoA oxygenase
LL042_RS01460	COG0318	PFAM AMP-dependent synthetase and ligase
LL042_RS01475	COG0604	alcohol dehydrogenase
LL042_RS01485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS01490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS01495	COG1595	DNA-templated transcription, initiation
LL042_RS01530	COG0656	L-ascorbic acid biosynthetic process
LL042_RS01555	COG1733	regulation of RNA biosynthetic process
LL042_RS01560	COG0596	Alpha beta hydrolase
LL042_RS01560	COG2945	thiolester hydrolase activity
LL042_RS01590	COG3940	Belongs to the glycosyl hydrolase 43 family
LL042_RS01595	COG1846	Transcriptional regulator
LL042_RS01600	COG2409	Drug exporters of the RND superfamily
LL042_RS01605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LL042_RS01620	COG2259	Doxx family
LL042_RS01680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LL042_RS01685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LL042_RS01710	COG0714	Associated with various cellular activities
LL042_RS01790	COG0667	Aldo Keto reductase
LL042_RS01815	COG0395	ABC-type sugar transport system, permease component
LL042_RS01820	COG1175	transmembrane transport
LL042_RS01840	COG1609	Transcriptional regulator
LL042_RS01850	COG1129	ABC transporter
LL042_RS01855	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL042_RS01860	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL042_RS01890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LL042_RS01895	COG0702	epimerase
LL042_RS01915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL042_RS01940	COG2124	cytochrome p450
LL042_RS01950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LL042_RS01960	COG4941	Belongs to the sigma-70 factor family
LL042_RS01965	COG3795	YCII-related domain
LL042_RS01970	COG1309	transcriptional regulator
LL042_RS01975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LL042_RS01985	COG0183	Belongs to the thiolase family
LL042_RS01990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LL042_RS02010	COG1414	Transcriptional regulator
LL042_RS02035	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LL042_RS02050	COG2259	Doxx family
LL042_RS02100	COG0395	ABC-type sugar transport system, permease component
LL042_RS02105	COG1175	transmembrane transport
LL042_RS02110	COG1653	transport
LL042_RS02115	COG1501	Belongs to the glycosyl hydrolase 31 family
LL042_RS02120	COG2326	polyphosphate kinase activity
LL042_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS02140	COG4209	transmembrane transport
LL042_RS02145	COG0395	ABC-type sugar transport system, permease component
LL042_RS02165	COG0110	maltose O-acetyltransferase activity
LL042_RS02175	COG0714	Associated with various cellular activities
LL042_RS02190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL042_RS02200	COG1120	ATPase activity
LL042_RS02220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LL042_RS02230	COG3290	protein histidine kinase activity
LL042_RS02240	COG0326	Molecular chaperone. Has ATPase activity
LL042_RS02265	COG0667	Aldo Keto reductase
LL042_RS02285	COG0559	Belongs to the binding-protein-dependent transport system permease family
LL042_RS02295	COG0410	ABC transporter
LL042_RS02300	COG2508	Transcriptional regulator
LL042_RS02355	COG3290	protein histidine kinase activity
LL042_RS02380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LL042_RS02380	COG1017	nitric oxide dioxygenase activity
LL042_RS02450	COG1132	(ABC) transporter
LL042_RS02455	COG0667	Aldo Keto reductase
LL042_RS02460	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LL042_RS02465	COG0673	inositol 2-dehydrogenase activity
LL042_RS02490	COG1554	hydrolase, family 65, central catalytic
LL042_RS02540	COG1309	transcriptional regulator
LL042_RS02560	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LL042_RS02600	COG1132	(ABC) transporter
LL042_RS02690	COG0248	Ppx GppA phosphatase
LL042_RS02705	COG2890	protein-(glutamine-N5) methyltransferase activity
LL042_RS02765	COG0667	Aldo Keto reductase
LL042_RS02785	COG0435	Glutathione S-transferase
LL042_RS02820	COG1796	DNA polymerase
LL042_RS02820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LL042_RS02835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LL042_RS02865	COG2706	6-phosphogluconolactonase activity
LL042_RS02875	COG1309	transcriptional regulator
LL042_RS02900	COG1609	Transcriptional regulator
LL042_RS02920	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL042_RS02925	COG1129	ABC transporter
LL042_RS02930	COG4952	isomerase
LL042_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS02935	COG3347	Dehydrogenase
LL042_RS02940	COG1070	Carbohydrate kinase
LL042_RS02945	COG0247	lactate metabolic process
LL042_RS02950	COG1139	Iron-sulfur cluster binding protein
LL042_RS02955	COG1556	Lactate utilization protein
LL042_RS02960	COG0577	efflux transmembrane transporter activity
LL042_RS02960	COG1136	(ABC) transporter
LL042_RS02970	COG0542	response to heat
LL042_RS03020	COG4585	Histidine kinase
LL042_RS03025	COG2197	response regulator
LL042_RS03040	COG0242	peptide deformylase activity
LL042_RS03050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL042_RS03055	COG1609	Transcriptional regulator
LL042_RS03075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL042_RS03080	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LL042_RS03085	COG2080	2 iron, 2 sulfur cluster binding
LL042_RS03095	COG0583	DNA-binding transcription factor activity
LL042_RS03105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL042_RS03125	COG1881	PFAM PEBP family protein
LL042_RS03145	COG1335	isochorismatase
LL042_RS03175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LL042_RS03180	COG0121	glutamine amidotransferase
LL042_RS03185	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LL042_RS03190	COG2182	Extracellular solute-binding protein
LL042_RS03195	COG3360	Dodecin
LL042_RS03205	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
LL042_RS03220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LL042_RS03225	COG1053	succinate dehydrogenase
LL042_RS03235	COG0583	DNA-binding transcription factor activity
LL042_RS03245	COG0726	polysaccharide deacetylase
LL042_RS03310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LL042_RS03355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LL042_RS03360	COG0297	glycogen (starch) synthase activity
LL042_RS03380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LL042_RS03395	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LL042_RS03410	COG2382	esterase
LL042_RS03410	COG3507	Belongs to the glycosyl hydrolase 43 family
LL042_RS03410	COG3693	PFAM glycoside hydrolase, family 10
LL042_RS03420	COG3693	PFAM glycoside hydrolase, family 10
LL042_RS03445	COG0179	Fumarylacetoacetate (FAA) hydrolase
LL042_RS03450	COG4948	Mandelate Racemase Muconate Lactonizing
LL042_RS03475	COG0247	lactate metabolic process
LL042_RS03475	COG0277	FAD linked oxidase domain protein
LL042_RS03480	COG0028	Belongs to the TPP enzyme family
LL042_RS03485	COG4948	Mandelate Racemase Muconate Lactonizing
LL042_RS03495	COG0300	oxidoreductase activity
LL042_RS03510	COG0513	Belongs to the DEAD box helicase family
LL042_RS03515	COG1132	(ABC) transporter
LL042_RS03520	COG2860	membrane
LL042_RS03530	COG1595	DNA-templated transcription, initiation
LL042_RS03565	COG1874	Beta-galactosidase
LL042_RS03565	COG0366	Alpha amylase catalytic
LL042_RS03575	COG1472	Belongs to the glycosyl hydrolase 3 family
LL042_RS03585	COG1175	transmembrane transport
LL042_RS03590	COG1653	transport
LL042_RS03595	COG1609	Transcriptional regulator
LL042_RS03605	COG0395	ABC-type sugar transport system, permease component
LL042_RS03670	COG4585	Histidine kinase
LL042_RS03675	COG2197	response regulator
LL042_RS03685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LL042_RS03690	COG1132	(ABC) transporter
LL042_RS03700	COG0668	transmembrane transport
LL042_RS03705	COG2838	Isocitrate dehydrogenase
LL042_RS03750	COG2814	Major facilitator Superfamily
LL042_RS03765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LL042_RS03770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL042_RS03775	COG2188	Transcriptional regulator
LL042_RS03780	COG0673	inositol 2-dehydrogenase activity
LL042_RS03785	COG1609	Transcriptional regulator
LL042_RS03795	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS03800	COG0673	inositol 2-dehydrogenase activity
LL042_RS03805	COG0673	inositol 2-dehydrogenase activity
LL042_RS03810	COG1312	Catalyzes the dehydration of D-mannonate
LL042_RS03830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL042_RS03840	COG3718	enzyme involved in inositol metabolism
LL042_RS03845	COG3962	Belongs to the TPP enzyme family
LL042_RS03850	COG2188	Transcriptional regulator
LL042_RS03895	COG0183	Belongs to the thiolase family
LL042_RS03950	COG3959	Transketolase, thiamine diphosphate binding domain
LL042_RS03955	COG3958	Transketolase
LL042_RS03980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL042_RS03980	COG2010	Cytochrome c
LL042_RS03990	COG0191	fructose-bisphosphate aldolase activity
LL042_RS04000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LL042_RS04005	COG0395	ABC-type sugar transport system, permease component
LL042_RS04020	COG1349	DNA-binding transcription factor activity
LL042_RS04030	COG0673	inositol 2-dehydrogenase activity
LL042_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS04070	COG1215	transferase activity, transferring glycosyl groups
LL042_RS04100	COG1349	DNA-binding transcription factor activity
LL042_RS04130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LL042_RS04135	COG1940	carbohydrate kinase activity
LL042_RS04145	COG2813	Specifically methylates the guanine in position
LL042_RS04150	COG3387	PFAM Glycoside hydrolase 15-related
LL042_RS04175	COG0673	inositol 2-dehydrogenase activity
LL042_RS04225	COG2197	response regulator
LL042_RS04230	COG4585	Histidine kinase
LL042_RS04245	COG1660	Displays ATPase and GTPase activities
LL042_RS04280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LL042_RS04330	COG0584	glycerophosphoryl diester phosphodiesterase
LL042_RS04365	COG0671	phosphoesterase, PA-phosphatase related
LL042_RS04370	COG1309	transcriptional regulator
LL042_RS04395	COG0640	Transcriptional regulator
LL042_RS04400	COG1902	pentaerythritol trinitrate reductase activity
LL042_RS04415	COG1960	acyl-CoA dehydrogenase activity
LL042_RS04425	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LL042_RS04450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL042_RS04495	COG0589	response to stress
LL042_RS04510	COG0477	Major facilitator Superfamily
LL042_RS04520	COG0432	Pfam Uncharacterised protein family UPF0047
LL042_RS04525	COG2072	flavoprotein involved in K transport
LL042_RS04530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LL042_RS04535	COG1132	(ABC) transporter
LL042_RS04545	COG1132	(ABC) transporter
LL042_RS04550	COG1132	(ABC) transporter
LL042_RS04560	COG0254	rRNA binding
LL042_RS04575	COG1946	Acyl-CoA thioesterase
LL042_RS04585	COG2018	Roadblock/LC7 domain
LL042_RS04625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LL042_RS04670	COG1960	acyl-CoA dehydrogenase activity
LL042_RS04675	COG1960	acyl-CoA dehydrogenase activity
LL042_RS04695	COG1793	dna ligase
LL042_RS04705	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS04720	COG1960	acyl-CoA dehydrogenase activity
LL042_RS04730	COG0242	peptide deformylase activity
LL042_RS04735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LL042_RS04740	COG3442	glutamine amidotransferase
LL042_RS04745	COG0205	6-phosphofructokinase activity
LL042_RS04765	COG3275	phosphorelay sensor kinase activity
LL042_RS04770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL042_RS04785	COG1522	sequence-specific DNA binding
LL042_RS04790	COG1834	amidinotransferase
LL042_RS04795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LL042_RS04815	COG0204	Acyl-transferase
LL042_RS04825	COG0829	nickel cation binding
LL042_RS04830	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LL042_RS04840	COG0804	urea catabolic process
LL042_RS04845	COG0832	Belongs to the urease beta subunit family
LL042_RS04850	COG0831	urea catabolic process
LL042_RS04860	COG0740	serine-type endopeptidase activity
LL042_RS04895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LL042_RS04900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LL042_RS04905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LL042_RS04910	COG2226	methyltransferase
LL042_RS04925	COG1136	(ABC) transporter
LL042_RS04925	COG0577	efflux transmembrane transporter activity
LL042_RS04935	COG0456	acetyltransferase
LL042_RS05070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LL042_RS05095	COG4585	Histidine kinase
LL042_RS05100	COG2197	response regulator
LL042_RS05105	COG1940	carbohydrate kinase activity
LL042_RS05110	COG2188	Transcriptional regulator
LL042_RS05115	COG1595	DNA-templated transcription, initiation
LL042_RS05125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL042_RS05140	COG0626	cystathionine gamma-synthase activity
LL042_RS05165	COG0419	ATPase involved in DNA repair
LL042_RS05170	COG0420	3'-5' exonuclease activity
LL042_RS05175	COG1739	Uncharacterized protein family UPF0029
LL042_RS05185	COG0215	cysteine-tRNA ligase activity
LL042_RS05190	COG1832	CoA-binding protein
LL042_RS05195	COG0640	Transcriptional regulator
LL042_RS05215	COG0110	maltose O-acetyltransferase activity
LL042_RS05250	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LL042_RS05270	COG1968	undecaprenyl-diphosphatase activity
LL042_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS05295	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LL042_RS05305	COG2318	DinB family
LL042_RS05320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LL042_RS05385	COG0697	spore germination
LL042_RS05445	COG1733	regulation of RNA biosynthetic process
LL042_RS05460	COG0725	ABC transporter, periplasmic molybdate-binding protein
LL042_RS05475	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LL042_RS05475	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LL042_RS05485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LL042_RS05505	COG1716	ATPase activity
LL042_RS05525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LL042_RS05555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LL042_RS05565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LL042_RS05580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LL042_RS05600	COG2018	Roadblock/LC7 domain
LL042_RS05640	COG2814	Major facilitator Superfamily
LL042_RS05645	COG4336	lyase activity
LL042_RS05650	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LL042_RS05655	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LL042_RS05660	COG1984	allophanate hydrolase subunit 2
LL042_RS05670	COG0438	transferase activity, transferring glycosyl groups
LL042_RS05675	COG0438	transferase activity, transferring glycosyl groups
LL042_RS05705	COG2364	Membrane
LL042_RS05715	COG2270	Major facilitator Superfamily
LL042_RS05725	COG3030	protein affecting phage T7 exclusion by the F plasmid
LL042_RS05730	COG0463	Glycosyl transferase, family 2
LL042_RS05750	COG1960	acyl-CoA dehydrogenase activity
LL042_RS05800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LL042_RS05805	COG0140	phosphoribosyl-ATP diphosphatase activity
LL042_RS05810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LL042_RS05815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LL042_RS05815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LL042_RS05820	COG3201	nicotinamide mononucleotide transporter
LL042_RS05830	COG1090	epimerase
LL042_RS05835	COG1846	Transcriptional regulator
LL042_RS05835	COG1940	carbohydrate kinase activity
LL042_RS05840	COG2223	nitrite transmembrane transporter activity
LL042_RS05850	COG2233	PERMEase
LL042_RS05870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LL042_RS05885	COG0531	amino acid
LL042_RS05900	COG2390	Transcriptional regulator
LL042_RS05905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LL042_RS05910	COG2409	Drug exporters of the RND superfamily
LL042_RS05920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LL042_RS05935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LL042_RS05945	COG1758	RNA polymerase activity
LL042_RS05950	COG0194	GDP metabolic process
LL042_RS05960	COG0284	orotidine-5'-phosphate decarboxylase activity
LL042_RS05965	COG0167	dihydroorotate dehydrogenase activity
LL042_RS05970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LL042_RS05975	COG0505	Belongs to the CarA family
LL042_RS05985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LL042_RS05990	COG0540	Belongs to the ATCase OTCase family
LL042_RS05995	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LL042_RS06005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LL042_RS06010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LL042_RS06015	COG0006	proline dipeptidase activity
LL042_RS06025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LL042_RS06030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LL042_RS06035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LL042_RS06045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LL042_RS06055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LL042_RS06060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LL042_RS06075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LL042_RS06090	COG0124	histidyl-tRNA synthetase
LL042_RS06100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LL042_RS06105	COG1196	nuclear chromosome segregation
LL042_RS06110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LL042_RS06115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LL042_RS06120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LL042_RS06125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LL042_RS06135	COG2255	four-way junction helicase activity
LL042_RS06140	COG0632	four-way junction helicase activity
LL042_RS06145	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LL042_RS06150	COG0217	transcriptional regulatory protein
LL042_RS06155	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LL042_RS06160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LL042_RS06170	COG0438	transferase activity, transferring glycosyl groups
LL042_RS06175	COG1560	Kdo2-lipid A biosynthetic process
LL042_RS06180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LL042_RS06200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LL042_RS06215	COG5002	protein histidine kinase activity
LL042_RS06215	COG2176	DNA-directed DNA polymerase activity
LL042_RS06240	COG0395	ABC-type sugar transport system, permease component
LL042_RS06245	COG1175	transmembrane transport
LL042_RS06300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LL042_RS06360	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LL042_RS06365	COG0475	glutathione-regulated potassium exporter activity
LL042_RS06370	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LL042_RS06400	COG1960	acyl-CoA dehydrogenase activity
LL042_RS06415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS06450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL042_RS06475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LL042_RS06475	COG1648	precorrin-2 dehydrogenase activity
LL042_RS06480	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LL042_RS06495	COG1464	Belongs to the NlpA lipoprotein family
LL042_RS06500	COG2011	ABC-type metal ion transport system permease component
LL042_RS06505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LL042_RS06535	COG0584	glycerophosphoryl diester phosphodiesterase
LL042_RS06540	COG0204	Acyl-transferase
LL042_RS06540	COG0318	PFAM AMP-dependent synthetase and ligase
LL042_RS06545	COG0477	Major facilitator Superfamily
LL042_RS06560	COG0165	Argininosuccinate lyase
LL042_RS06565	COG0137	argininosuccinate synthase activity
LL042_RS06600	COG1438	arginine binding
LL042_RS06605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LL042_RS06610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LL042_RS06615	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LL042_RS06620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LL042_RS06630	COG2259	Doxx family
LL042_RS06660	COG0697	spore germination
LL042_RS06670	COG1649	PFAM Uncharacterised BCR, COG1649
LL042_RS06695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL042_RS06695	COG0072	phenylalanine-tRNA ligase activity
LL042_RS06700	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LL042_RS06705	COG5002	protein histidine kinase activity
LL042_RS06710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LL042_RS06715	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LL042_RS06720	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LL042_RS06725	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LL042_RS06770	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS06775	COG0174	glutamine synthetase
LL042_RS06785	COG0531	amino acid
LL042_RS06790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LL042_RS06805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LL042_RS06815	COG4176	ABC-type proline glycine betaine transport system permease component
LL042_RS06820	COG0517	IMP dehydrogenase activity
LL042_RS06820	COG4175	Glycine betaine
LL042_RS06825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL042_RS06840	COG0564	pseudouridine synthase activity
LL042_RS06880	COG0805	protein transport
LL042_RS06885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LL042_RS06905	COG2378	regulation of single-species biofilm formation
LL042_RS06915	COG0545	Peptidyl-prolyl cis-trans isomerase
LL042_RS06920	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LL042_RS06930	COG1609	Transcriptional regulator
LL042_RS06935	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LL042_RS06940	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LL042_RS06955	COG4122	O-methyltransferase activity
LL042_RS06960	COG1222	aaa ATPase
LL042_RS06980	COG0517	IMP dehydrogenase activity
LL042_RS06980	COG1994	Peptidase M50
LL042_RS06990	COG2197	response regulator
LL042_RS06995	COG4166	transmembrane transport
LL042_RS07000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL042_RS07005	COG0646	methionine synthase
LL042_RS07005	COG1410	methionine synthase
LL042_RS07010	COG1414	Transcriptional regulator
LL042_RS07015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LL042_RS07020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LL042_RS07025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LL042_RS07030	COG2186	Transcriptional regulator
LL042_RS07040	COG0215	cysteine-tRNA ligase activity
LL042_RS07055	COG0588	phosphoglycerate mutase activity
LL042_RS07060	COG0598	Magnesium transport protein CorA
LL042_RS07070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL042_RS07075	COG0667	Aldo Keto reductase
LL042_RS07105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL042_RS07115	COG3012	SEC-C Motif Domain Protein
LL042_RS07120	COG2186	Transcriptional regulator
LL042_RS07125	COG3265	gluconokinase activity
LL042_RS07160	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LL042_RS07165	COG2149	membrane
LL042_RS07185	COG1960	acyl-CoA dehydrogenase activity
LL042_RS07210	COG3876	Protein conserved in bacteria
LL042_RS07240	COG1960	acyl-CoA dehydrogenase activity
LL042_RS07250	COG0640	Transcriptional regulator
LL042_RS07275	COG2851	Citrate transporter
LL042_RS07280	COG0243	molybdopterin cofactor binding
LL042_RS07285	COG1309	transcriptional regulator
LL042_RS07295	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LL042_RS07300	COG2188	Transcriptional regulator
LL042_RS07335	COG1595	DNA-templated transcription, initiation
LL042_RS07355	COG2815	serine threonine protein kinase
LL042_RS07355	COG0515	serine threonine protein kinase
LL042_RS07360	COG2755	lipolytic protein G-D-S-L family
LL042_RS07375	COG0726	polysaccharide deacetylase
LL042_RS07375	COG1649	PFAM Uncharacterised BCR, COG1649
LL042_RS07390	COG1725	Transcriptional regulator
LL042_RS07435	COG0587	DNA-directed DNA polymerase activity
LL042_RS07460	COG1799	cell septum assembly
LL042_RS07465	COG1960	acyl-CoA dehydrogenase activity
LL042_RS07470	COG0477	Major facilitator Superfamily
LL042_RS07480	COG0671	phosphoesterase, PA-phosphatase related
LL042_RS07510	COG1160	GTP binding
LL042_RS07520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LL042_RS07550	COG1187	pseudouridine synthase activity
LL042_RS07555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LL042_RS07560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LL042_RS07575	COG0686	Belongs to the AlaDH PNT family
LL042_RS07585	COG0494	nUDIX hydrolase
LL042_RS07590	COG0504	CTP synthase activity
LL042_RS07595	COG3387	PFAM Glycoside hydrolase 15-related
LL042_RS07610	COG0497	DNA recombination
LL042_RS07615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LL042_RS07635	COG1120	ATPase activity
LL042_RS07640	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL042_RS07645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL042_RS07650	COG0647	UMP catabolic process
LL042_RS07685	COG2094	Belongs to the DNA glycosylase MPG family
LL042_RS07695	COG1881	PFAM PEBP family protein
LL042_RS07715	COG1119	ATPase activity
LL042_RS07730	COG2197	response regulator
LL042_RS07740	COG4221	oxidoreductase activity
LL042_RS07745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LL042_RS07755	COG1131	(ABC) transporter
LL042_RS07755	COG1716	ATPase activity
LL042_RS07755	COG0842	Transport permease protein
LL042_RS07765	COG0560	Phosphoserine phosphatase
LL042_RS07765	COG3830	Belongs to the UPF0237 family
LL042_RS07770	COG0588	phosphoglycerate mutase activity
LL042_RS07785	COG2186	Transcriptional regulator
LL042_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS07800	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
LL042_RS07820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LL042_RS07840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LL042_RS07845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL042_RS07865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL042_RS07875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LL042_RS07905	COG3387	PFAM Glycoside hydrolase 15-related
LL042_RS07950	COG1024	Enoyl-CoA hydratase
LL042_RS07960	COG0488	(ABC) transporter
LL042_RS07980	COG0235	Class ii aldolase
LL042_RS07995	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LL042_RS08000	COG1492	cobalamin metabolic process
LL042_RS08020	COG1797	cobyrinic acid a,c-diamide synthase activity
LL042_RS08080	COG0765	amino acid transport
LL042_RS08090	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LL042_RS08095	COG0456	acetyltransferase
LL042_RS08100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LL042_RS08105	COG1917	Cupin 2, conserved barrel domain protein
LL042_RS08110	COG5285	phytanoyl-CoA dioxygenase
LL042_RS08115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LL042_RS08135	COG4585	Histidine kinase
LL042_RS08140	COG2197	response regulator
LL042_RS08150	COG1414	Transcriptional regulator
LL042_RS08160	COG0768	penicillin binding
LL042_RS08165	COG1595	DNA-templated transcription, initiation
LL042_RS08180	COG3507	Belongs to the glycosyl hydrolase 43 family
LL042_RS08190	COG4677	pectinesterase activity
LL042_RS08195	COG3866	Pectate lyase
LL042_RS08200	COG2755	lipolytic protein G-D-S-L family
LL042_RS08210	COG3507	Belongs to the glycosyl hydrolase 43 family
LL042_RS08225	COG0395	ABC-type sugar transport system, permease component
LL042_RS08240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL042_RS08245	COG1802	Transcriptional regulator
LL042_RS08265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL042_RS08270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LL042_RS08275	COG1349	DNA-binding transcription factor activity
LL042_RS08290	COG0395	ABC-type sugar transport system, permease component
LL042_RS08295	COG1063	alcohol dehydrogenase
LL042_RS08340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL042_RS08350	COG1595	DNA-templated transcription, initiation
LL042_RS08355	COG2171	N-acyltransferase activity
LL042_RS08365	COG2151	metal-sulfur cluster biosynthetic enzyme
LL042_RS08370	COG0822	iron-sulfur transferase activity
LL042_RS08375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LL042_RS08380	COG0396	ATPase activity
LL042_RS08390	COG0719	Fe-S assembly protein
LL042_RS08405	COG1131	(ABC) transporter
LL042_RS08415	COG1612	heme a metabolic process
LL042_RS08435	COG0109	protoheme IX farnesyltransferase activity
LL042_RS08445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LL042_RS08460	COG0363	glucosamine-6-phosphate deaminase activity
LL042_RS08465	COG0395	ABC-type sugar transport system, permease component
LL042_RS08470	COG1175	transmembrane transport
LL042_RS08475	COG1653	transport
LL042_RS08480	COG0366	Alpha amylase catalytic
LL042_RS08485	COG1653	transport
LL042_RS08490	COG1695	Transcriptional regulator
LL042_RS08495	COG0577	efflux transmembrane transporter activity
LL042_RS08495	COG1136	(ABC) transporter
LL042_RS08510	COG0166	Belongs to the GPI family
LL042_RS08520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LL042_RS08525	COG0149	triose-phosphate isomerase activity
LL042_RS08530	COG0126	phosphoglycerate kinase activity
LL042_RS08535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LL042_RS08545	COG1481	regulation of sporulation
LL042_RS08550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LL042_RS08555	COG1660	Displays ATPase and GTPase activities
LL042_RS08560	COG0322	excinuclease ABC activity
LL042_RS08575	COG0723	plastoquinol--plastocyanin reductase activity
LL042_RS08580	COG1609	Transcriptional regulator
LL042_RS08585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL042_RS08590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LL042_RS08600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL042_RS08605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LL042_RS08610	COG0387	Pfam Sodium calcium exchanger
LL042_RS08630	COG0556	nucleotide-excision repair
LL042_RS08640	COG0584	glycerophosphoryl diester phosphodiesterase
LL042_RS08645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LL042_RS08655	COG2313	pseudouridylate synthase activity
LL042_RS08785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LL042_RS08790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LL042_RS08795	COG2267	carboxylic ester hydrolase activity
LL042_RS08805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LL042_RS08810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LL042_RS08825	COG0237	dephospho-CoA kinase activity
LL042_RS08835	COG0539	negative regulation of cytoplasmic translation
LL042_RS08845	COG1643	Atp-dependent helicase
LL042_RS08875	COG2050	protein possibly involved in aromatic compounds catabolism
LL042_RS08900	COG0411	ABC transporter
LL042_RS08930	COG0737	Belongs to the 5'-nucleotidase family
LL042_RS08935	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LL042_RS08945	COG0745	RESPONSE REGULATOR receiver
LL042_RS08950	COG0287	Prephenate dehydrogenase
LL042_RS08950	COG1605	Chorismate mutase
LL042_RS08960	COG2304	oxidoreductase activity
LL042_RS08980	COG0069	glutamate synthase activity
LL042_RS08980	COG0070	glutamate synthase
LL042_RS08980	COG0067	glutamate synthase
LL042_RS08990	COG1397	ADP-ribosylglycohydrolase
LL042_RS09010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL042_RS09015	COG2301	Belongs to the HpcH HpaI aldolase family
LL042_RS09020	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LL042_RS09030	COG0159	tryptophan synthase activity
LL042_RS09035	COG0133	tryptophan synthase activity
LL042_RS09040	COG0134	indole-3-glycerol-phosphate synthase activity
LL042_RS09060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LL042_RS09065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LL042_RS09080	COG0107	imidazoleglycerol-phosphate synthase activity
LL042_RS09085	COG0251	oxidation-reduction process
LL042_RS09090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LL042_RS09095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LL042_RS09105	COG0131	Imidazoleglycerol-phosphate dehydratase
LL042_RS09110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LL042_RS09115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LL042_RS09140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LL042_RS09160	COG1432	Conserved Protein
LL042_RS09175	COG0587	DNA-directed DNA polymerase activity
LL042_RS09235	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LL042_RS09245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LL042_RS09250	COG3599	regulation of cell shape
LL042_RS09260	COG1799	cell septum assembly
LL042_RS09270	COG1496	oxidoreductase activity
LL042_RS09275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LL042_RS09280	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LL042_RS09285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LL042_RS09295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LL042_RS09300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LL042_RS09310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LL042_RS09325	COG0275	rRNA processing
LL042_RS09335	COG0714	Associated with various cellular activities
LL042_RS09365	COG1129	ABC transporter
LL042_RS09375	COG1309	transcriptional regulator
LL042_RS09395	COG0352	thiamine-phosphate diphosphorylase activity
LL042_RS09415	COG2022	thiamine diphosphate biosynthetic process
LL042_RS09415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LL042_RS09425	COG2022	thiamine diphosphate biosynthetic process
LL042_RS09430	COG0515	serine threonine protein kinase
LL042_RS09430	COG2815	serine threonine protein kinase
LL042_RS09435	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LL042_RS09440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LL042_RS09445	COG2193	ferroxidase activity
LL042_RS09455	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LL042_RS09465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL042_RS09475	COG4585	Histidine kinase
LL042_RS09500	COG1940	carbohydrate kinase activity
LL042_RS09510	COG0003	Pfam Anion-transporting ATPase
LL042_RS09550	COG1388	LysM domain
LL042_RS09550	COG0791	NLP P60 protein
LL042_RS09550	COG3103	Sh3 type 3 domain protein
LL042_RS09575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LL042_RS09580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LL042_RS09585	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LL042_RS09590	COG0723	plastoquinol--plastocyanin reductase activity
LL042_RS09595	COG2010	Cytochrome c
LL042_RS09600	COG1845	cytochrome c oxidase, subunit III
LL042_RS09610	COG1376	ErfK ybiS ycfS ynhG family protein
LL042_RS09620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LL042_RS09625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LL042_RS09635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL042_RS09655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LL042_RS09660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LL042_RS09665	COG2197	response regulator
LL042_RS09710	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LL042_RS09720	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LL042_RS09735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LL042_RS09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LL042_RS09745	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL042_RS09755	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LL042_RS09805	COG0321	lipoyl(octanoyl) transferase activity
LL042_RS09810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LL042_RS09830	COG0174	glutamine synthetase
LL042_RS09840	COG0501	Belongs to the peptidase M48B family
LL042_RS09870	COG0745	RESPONSE REGULATOR receiver
LL042_RS09885	COG2197	response regulator
LL042_RS09910	COG1309	transcriptional regulator
LL042_RS09935	COG0366	Alpha amylase catalytic
LL042_RS09940	COG3833	ABC-type maltose transport systems, permease component
LL042_RS09945	COG1175	transmembrane transport
LL042_RS09950	COG1653	transport
LL042_RS09955	COG1609	Transcriptional regulator
LL042_RS09965	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LL042_RS09990	COG0174	glutamine synthetase
LL042_RS09995	COG1959	2 iron, 2 sulfur cluster binding
LL042_RS10010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LL042_RS10010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LL042_RS10025	COG0477	Major facilitator Superfamily
LL042_RS10030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LL042_RS10050	COG1994	Peptidase M50
LL042_RS10095	COG2837	iron assimilation
LL042_RS10100	COG0672	)-iron permease
LL042_RS10115	COG0584	glycerophosphoryl diester phosphodiesterase
LL042_RS10120	COG1309	transcriptional regulator
LL042_RS10135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LL042_RS10140	COG2814	Major facilitator Superfamily
LL042_RS10160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL042_RS10165	COG1414	Transcriptional regulator
LL042_RS10175	COG2409	Drug exporters of the RND superfamily
LL042_RS10180	COG0142	geranyltranstransferase activity
LL042_RS10210	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS10215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LL042_RS10220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LL042_RS10225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS10240	COG0183	Belongs to the thiolase family
LL042_RS10245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL042_RS10250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS10280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS10285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS10300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS10310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS10310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS10315	COG2124	cytochrome p450
LL042_RS10330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LL042_RS10350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS10355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL042_RS10390	COG1652	LysM domain
LL042_RS10400	COG0515	serine threonine protein kinase
LL042_RS10400	COG2815	serine threonine protein kinase
LL042_RS10405	COG1205	dead DEAH box helicase
LL042_RS10405	COG1111	helicase
LL042_RS10415	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LL042_RS10430	COG1476	TRANSCRIPTIONal
LL042_RS10450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LL042_RS10465	COG2124	cytochrome p450
LL042_RS10470	COG2124	cytochrome p450
LL042_RS10520	COG3022	response to hydroperoxide
LL042_RS10525	COG0800	Aldolase
LL042_RS10540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LL042_RS10555	COG2030	dehydratase
LL042_RS10560	COG4585	Histidine kinase
LL042_RS10565	COG2197	response regulator
LL042_RS10575	COG0477	Major facilitator Superfamily
LL042_RS10610	COG0438	transferase activity, transferring glycosyl groups
LL042_RS10615	COG1309	transcriptional regulator
LL042_RS10640	COG3845	ABC transporter
LL042_RS10665	COG4122	O-methyltransferase activity
LL042_RS10705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL042_RS10765	COG0586	Pfam SNARE associated Golgi protein
LL042_RS10775	COG1358	cellular component organization or biogenesis
LL042_RS10820	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LL042_RS10830	COG0477	Major facilitator Superfamily
LL042_RS10835	COG1309	transcriptional regulator
LL042_RS10850	COG0789	Transcriptional regulator
LL042_RS10900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL042_RS10905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL042_RS10910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL042_RS10935	COG1280	lysine exporter protein (LysE YggA)
LL042_RS10945	COG2130	NADP-dependent
LL042_RS10975	COG4213	ABC transporter substrate-binding protein
LL042_RS10985	COG4214	carbohydrate transport
LL042_RS10995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LL042_RS11000	COG3507	Belongs to the glycosyl hydrolase 43 family
LL042_RS11035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LL042_RS11060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LL042_RS11105	COG0395	ABC-type sugar transport system, permease component
LL042_RS11110	COG1175	transmembrane transport
LL042_RS11140	COG3386	PFAM SMP-30 Gluconolaconase
LL042_RS11145	COG1414	Transcriptional regulator
LL042_RS11165	COG2186	Transcriptional regulator
LL042_RS11175	COG0318	PFAM AMP-dependent synthetase and ligase
LL042_RS11180	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LL042_RS11180	COG0825	malonyl-CoA metabolic process
LL042_RS11185	COG1077	Cell shape determining protein MreB Mrl
LL042_RS11230	COG1070	Carbohydrate kinase
LL042_RS11245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LL042_RS11250	COG0358	DNA primase activity
LL042_RS11260	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LL042_RS11270	COG2949	membrane
LL042_RS11275	COG0243	molybdopterin cofactor binding
LL042_RS11300	COG1733	regulation of RNA biosynthetic process
LL042_RS11320	COG2146	nitrite reductase [NAD(P)H] activity
LL042_RS11320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LL042_RS11325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LL042_RS11325	COG2146	nitrite reductase [NAD(P)H] activity
LL042_RS11345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LL042_RS11345	COG0574	Belongs to the PEP-utilizing enzyme family
LL042_RS11370	COG0423	glycine-tRNA ligase activity
LL042_RS11375	COG0803	Belongs to the bacterial solute-binding protein 9 family
LL042_RS11375	COG3443	Belongs to the bacterial solute-binding protein 9 family
LL042_RS11380	COG1120	ATPase activity
LL042_RS11385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LL042_RS11400	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LL042_RS11405	COG1381	Involved in DNA repair and RecF pathway recombination
LL042_RS11440	COG2197	response regulator
LL042_RS11445	COG4585	Histidine kinase
LL042_RS11450	COG2409	Drug exporters of the RND superfamily
LL042_RS11495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LL042_RS11515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LL042_RS11525	COG2315	Protein conserved in bacteria
LL042_RS11535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LL042_RS11545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL042_RS11550	COG4948	Mandelate Racemase Muconate Lactonizing
LL042_RS11555	COG1414	Transcriptional regulator
LL042_RS11565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LL042_RS11570	COG1234	tRNA 3'-trailer cleavage
LL042_RS11575	COG0537	adenosine 5'-monophosphoramidase activity
LL042_RS11580	COG0793	Belongs to the peptidase S41A family
LL042_RS11580	COG4946	Tricorn protease homolog
LL042_RS11600	COG0484	heat shock protein binding
LL042_RS11605	COG1420	regulation of RNA biosynthetic process
LL042_RS11635	COG0481	GTPase activity
LL042_RS11640	COG0268	Binds directly to 16S ribosomal RNA
LL042_RS11670	COG1307	EDD domain protein, DegV family
LL042_RS11680	COG0495	leucyl-tRNA aminoacylation
LL042_RS11690	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LL042_RS11715	COG0588	phosphoglycerate mutase activity
LL042_RS11720	COG0799	negative regulation of ribosome biogenesis
LL042_RS11730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LL042_RS11740	COG0501	Belongs to the peptidase M48B family
LL042_RS11755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LL042_RS11765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LL042_RS11780	COG1215	transferase activity, transferring glycosyl groups
LL042_RS11795	COG3540	Alkaline phosphatase
LL042_RS11805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LL042_RS11810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LL042_RS11815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LL042_RS11840	COG1530	ribonuclease E activity
LL042_RS11870	COG0772	Belongs to the SEDS family
LL042_RS11875	COG0768	penicillin binding
LL042_RS11890	COG1077	Cell shape determining protein MreB Mrl
LL042_RS11895	COG0105	UTP biosynthetic process
LL042_RS11905	COG0285	dihydrofolate synthase activity
LL042_RS11915	COG0525	valine-tRNA ligase activity
LL042_RS11925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LL042_RS11930	COG0740	serine-type endopeptidase activity
LL042_RS11935	COG0740	serine-type endopeptidase activity
LL042_RS11940	COG0544	peptidyl-prolyl cis-trans isomerase activity
LL042_RS11960	COG3594	Acyltransferase
LL042_RS11975	COG4552	Acetyltransferase involved in intracellular survival and related
LL042_RS11990	COG1113	amino acid transport
LL042_RS12000	COG1113	amino acid transport
LL042_RS12010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LL042_RS12070	COG1309	transcriptional regulator
LL042_RS12080	COG0697	spore germination
LL042_RS12085	COG1846	Transcriptional regulator
LL042_RS12105	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LL042_RS12105	COG3291	Pkd domain containing protein
LL042_RS12115	COG1136	(ABC) transporter
LL042_RS12130	COG0668	transmembrane transport
LL042_RS12140	COG1486	melibiose metabolic process
LL042_RS12185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LL042_RS12205	COG1136	(ABC) transporter
LL042_RS12245	COG0629	single-stranded DNA binding
LL042_RS12295	COG2304	oxidoreductase activity
LL042_RS12325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LL042_RS12335	COG0728	peptidoglycan biosynthetic process
LL042_RS12345	COG0438	transferase activity, transferring glycosyl groups
LL042_RS12360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LL042_RS12365	COG0492	ferredoxin-NADP+ reductase activity
LL042_RS12380	COG1131	(ABC) transporter
LL042_RS12415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LL042_RS12460	COG1609	Transcriptional regulator
LL042_RS12465	COG1129	ABC transporter
LL042_RS12475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL042_RS12480	COG1869	D-ribose catabolic process
LL042_RS12495	COG0673	inositol 2-dehydrogenase activity
LL042_RS12500	COG1609	Transcriptional regulator
LL042_RS12515	COG0697	spore germination
LL042_RS12525	COG1472	Belongs to the glycosyl hydrolase 3 family
LL042_RS12555	COG2356	endonuclease I
LL042_RS12565	COG0028	Belongs to the TPP enzyme family
LL042_RS12585	COG1946	Acyl-CoA thioesterase
LL042_RS12595	COG1309	transcriptional regulator
LL042_RS12600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL042_RS12615	COG1960	acyl-CoA dehydrogenase activity
LL042_RS12630	COG3409	Peptidoglycan-binding domain 1 protein
LL042_RS12655	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LL042_RS12680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LL042_RS12685	COG0589	response to stress
LL042_RS12690	COG4977	sequence-specific DNA binding
LL042_RS12695	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LL042_RS12720	COG0395	ABC-type sugar transport system, permease component
LL042_RS12730	COG3979	chitinase
LL042_RS12740	COG0745	RESPONSE REGULATOR receiver
LL042_RS12750	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LL042_RS12765	COG0406	alpha-ribazole phosphatase activity
LL042_RS12815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL042_RS12830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL042_RS12845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL042_RS12850	COG0765	amino acid transport
LL042_RS12855	COG0765	amino acid transport
LL042_RS12860	COG1126	abc transporter atp-binding protein
LL042_RS12870	COG3397	chitin binding
LL042_RS12915	COG1940	carbohydrate kinase activity
LL042_RS12920	COG0673	inositol 2-dehydrogenase activity
LL042_RS12925	COG4702	Belongs to the UPF0303 family
LL042_RS12935	COG0706	membrane insertase activity
LL042_RS12960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LL042_RS13020	COG3467	pyridoxamine 5'-phosphate
LL042_RS13025	COG1309	transcriptional regulator
LL042_RS13030	COG4106	trans-aconitate 2-methyltransferase activity
LL042_RS13035	COG3226	Transcriptional regulator
LL042_RS13065	COG2271	Major facilitator Superfamily
LL042_RS13070	COG2733	membrane
LL042_RS13085	COG4555	ABC transporter
LL042_RS13100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL042_RS13140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LL042_RS13150	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LL042_RS13155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL042_RS13160	COG1263	PTS System
LL042_RS13165	COG1263	PTS System
LL042_RS13170	COG1234	tRNA 3'-trailer cleavage
LL042_RS13195	COG1113	amino acid transport
LL042_RS13205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LL042_RS13215	COG1335	isochorismatase
LL042_RS13245	COG0277	FAD linked oxidase domain protein
LL042_RS13255	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LL042_RS13265	COG1174	glycine betaine transport
LL042_RS13275	COG1174	glycine betaine transport
LL042_RS13280	COG1732	Glycine betaine
LL042_RS13295	COG1061	Type III restriction enzyme res subunit
LL042_RS13300	COG3654	unkown
LL042_RS13330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL042_RS13345	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LL042_RS13350	COG0395	ABC-type sugar transport system, permease component
LL042_RS13370	COG1678	Uncharacterized ACR, COG1678
LL042_RS13375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LL042_RS13380	COG0776	regulation of translation
LL042_RS13390	COG3973	AAA domain
LL042_RS13415	COG2223	nitrite transmembrane transporter activity
LL042_RS13480	COG0583	DNA-binding transcription factor activity
LL042_RS13490	COG1609	Transcriptional regulator
LL042_RS13505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LL042_RS13510	COG0793	Belongs to the peptidase S41A family
LL042_RS13520	COG2884	Cell division ATP-binding protein ftsE
LL042_RS13535	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LL042_RS13540	COG0515	serine threonine protein kinase
LL042_RS13545	COG0515	serine threonine protein kinase
LL042_RS13560	COG1175	transmembrane transport
LL042_RS13565	COG0395	ABC-type sugar transport system, permease component
LL042_RS13570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL042_RS13570	COG0463	Glycosyl transferase, family 2
LL042_RS13575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL042_RS13580	COG1216	Glycosyl transferase, family 2
LL042_RS13595	COG1764	response to oxidative stress
LL042_RS13600	COG1846	Transcriptional regulator
LL042_RS13605	COG1215	transferase activity, transferring glycosyl groups
LL042_RS13625	COG1134	teichoic acid transport
LL042_RS13625	COG1388	LysM domain
LL042_RS13630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL042_RS13635	COG1215	transferase activity, transferring glycosyl groups
LL042_RS13645	COG2902	Dehydrogenase
LL042_RS13665	COG0653	protein targeting
LL042_RS13675	COG3214	Protein conserved in bacteria
LL042_RS13680	COG2197	response regulator
LL042_RS13685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LL042_RS13695	COG0823	Involved in the tonB-independent uptake of proteins
LL042_RS13700	COG5002	protein histidine kinase activity
LL042_RS13705	COG0745	RESPONSE REGULATOR receiver
LL042_RS13710	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LL042_RS13730	COG0714	Associated with various cellular activities
LL042_RS13770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LL042_RS13780	COG1482	cell wall glycoprotein biosynthetic process
LL042_RS13790	COG2835	tetraacyldisaccharide 4'-kinase activity
LL042_RS13795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LL042_RS13800	COG1620	l-lactate permease
LL042_RS13835	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LL042_RS13840	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LL042_RS13840	COG0778	Nitroreductase
LL042_RS13865	COG1316	TRANSCRIPTIONal
LL042_RS13870	COG1316	TRANSCRIPTIONal
LL042_RS13875	COG1316	TRANSCRIPTIONal
LL042_RS13880	COG1316	TRANSCRIPTIONal
LL042_RS13890	COG1316	TRANSCRIPTIONal
LL042_RS13900	COG1316	TRANSCRIPTIONal
LL042_RS13910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LL042_RS13920	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LL042_RS13950	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LL042_RS13965	COG2205	protein histidine kinase activity
LL042_RS13970	COG0745	RESPONSE REGULATOR receiver
LL042_RS13975	COG3104	oligopeptide transport
LL042_RS13985	COG1366	Belongs to the anti-sigma-factor antagonist family
LL042_RS13990	COG1191	sigma factor activity
LL042_RS13995	COG1228	amidohydrolase
LL042_RS14010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LL042_RS14045	COG2755	lipolytic protein G-D-S-L family
LL042_RS14050	COG0183	Belongs to the thiolase family
LL042_RS14085	COG0577	efflux transmembrane transporter activity
LL042_RS14085	COG1136	(ABC) transporter
LL042_RS14090	COG0577	efflux transmembrane transporter activity
LL042_RS14095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LL042_RS14100	COG1252	NADH dehydrogenase
LL042_RS14120	COG0148	phosphopyruvate hydratase activity
LL042_RS14195	COG0577	efflux transmembrane transporter activity
LL042_RS14200	COG1136	(ABC) transporter
LL042_RS14230	COG4585	Histidine kinase
LL042_RS14245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LL042_RS14250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LL042_RS14255	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LL042_RS14260	COG0193	aminoacyl-tRNA hydrolase activity
LL042_RS14270	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LL042_RS14280	COG1309	transcriptional regulator
LL042_RS14285	COG4106	trans-aconitate 2-methyltransferase activity
LL042_RS14295	COG2197	response regulator
LL042_RS14305	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LL042_RS14345	COG0488	(ABC) transporter
LL042_RS14350	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LL042_RS14355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LL042_RS14360	COG0084	hydrolase, TatD family'
LL042_RS14400	COG0310	cobalt ion transport
LL042_RS14410	COG1122	ATPase activity
LL042_RS14415	COG1846	Transcriptional regulator
LL042_RS14420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LL042_RS14445	COG2409	Drug exporters of the RND superfamily
LL042_RS14455	COG4946	Tricorn protease homolog
LL042_RS14455	COG0793	Belongs to the peptidase S41A family
LL042_RS14470	COG2267	carboxylic ester hydrolase activity
LL042_RS14475	COG2072	flavoprotein involved in K transport
LL042_RS14490	COG0708	Exodeoxyribonuclease III
LL042_RS14530	COG0521	Mo-molybdopterin cofactor biosynthetic process
LL042_RS14530	COG0315	cyclic pyranopterin monophosphate synthase activity
LL042_RS14535	COG0315	cyclic pyranopterin monophosphate synthase activity
LL042_RS14545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LL042_RS14550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LL042_RS14575	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LL042_RS14610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL042_RS14610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LL042_RS14610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LL042_RS14620	COG1349	DNA-binding transcription factor activity
LL042_RS14625	COG0477	Major facilitator Superfamily
LL042_RS14645	COG1247	-acetyltransferase
LL042_RS14650	COG3384	dioxygenase
LL042_RS14655	COG1846	Transcriptional regulator
LL042_RS14680	COG0582	viral genome integration into host DNA
LL042_RS14745	COG2801	Transposase and inactivated derivatives
LL042_RS14745	COG3415	Transposase
LL042_RS14765	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LL042_RS14775	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LL042_RS14780	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LL042_RS14825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LL042_RS14845	COG0076	glutamate decarboxylase activity
LL042_RS14925	COG0386	Belongs to the glutathione peroxidase family
LL042_RS14950	COG1686	Belongs to the peptidase S11 family
LL042_RS14975	COG0515	serine threonine protein kinase
LL042_RS14975	COG2815	serine threonine protein kinase
LL042_RS14995	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LL042_RS15015	COG3629	intracellular signal transduction
LL042_RS15015	COG3903	Transcriptional regulator
LL042_RS15030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LL042_RS15030	COG0515	serine threonine protein kinase
LL042_RS15040	COG1309	transcriptional regulator
LL042_RS15050	COG0259	pyridoxamine-phosphate oxidase activity
LL042_RS15060	COG2072	flavoprotein involved in K transport
LL042_RS15065	COG2271	Major facilitator Superfamily
LL042_RS15140	COG0596	Alpha beta hydrolase
LL042_RS15140	COG2945	thiolester hydrolase activity
LL042_RS15150	COG4821	SIS domain
LL042_RS15165	COG2252	PERMEase
LL042_RS15175	COG0259	pyridoxamine-phosphate oxidase activity
LL042_RS15190	COG0318	PFAM AMP-dependent synthetase and ligase
LL042_RS15205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL042_RS15230	COG5006	permease, DMT superfamily
LL042_RS15240	COG0277	FAD linked oxidase domain protein
LL042_RS15240	COG0247	lactate metabolic process
LL042_RS15275	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LL042_RS15310	COG0667	Aldo Keto reductase
LL042_RS15340	COG2252	PERMEase
LL042_RS15350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LL042_RS15360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LL042_RS15360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LL042_RS15380	COG0739	heme binding
LL042_RS15415	COG2814	Major facilitator Superfamily
LL042_RS15425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LL042_RS15430	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LL042_RS15460	COG1061	Type III restriction enzyme res subunit
LL042_RS15470	COG3973	AAA domain
LL042_RS15485	COG1404	Belongs to the peptidase S8 family
LL042_RS15510	COG1737	Transcriptional regulator
LL042_RS15515	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LL042_RS15540	COG0459	protein refolding
LL042_RS15545	COG1278	Cold shock
LL042_RS15560	COG0463	Glycosyl transferase, family 2
LL042_RS15585	COG1940	carbohydrate kinase activity
LL042_RS15605	COG3300	MHYT domain
LL042_RS15605	COG5001	Diguanylate cyclase
LL042_RS15620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LL042_RS15670	COG2378	regulation of single-species biofilm formation
LL042_RS15675	COG3842	ATPase activity
LL042_RS15700	COG0215	cysteine-tRNA ligase activity
LL042_RS15705	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LL042_RS15710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LL042_RS15715	COG1329	Transcriptional regulator
LL042_RS15730	COG5002	protein histidine kinase activity
LL042_RS15750	COG0588	phosphoglycerate mutase activity
LL042_RS15765	COG1396	sequence-specific DNA binding
LL042_RS15770	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LL042_RS15845	COG0438	transferase activity, transferring glycosyl groups
LL042_RS15890	COG2318	DinB family
LL042_RS15895	COG0395	ABC-type sugar transport system, permease component
LL042_RS15900	COG1175	transmembrane transport
LL042_RS15905	COG1653	transport
LL042_RS15910	COG0156	8-amino-7-oxononanoate synthase activity
LL042_RS15915	COG2186	Transcriptional regulator
LL042_RS15920	COG3973	AAA domain
LL042_RS15940	COG0546	phosphoglycolate phosphatase activity
LL042_RS15945	COG2188	Transcriptional regulator
LL042_RS15965	COG4552	Acetyltransferase involved in intracellular survival and related
LL042_RS15975	COG1490	D-aminoacyl-tRNA deacylase activity
LL042_RS15985	COG0735	belongs to the Fur family
LL042_RS15990	COG3485	protocatechuate 3,4-dioxygenase
LL042_RS16025	COG2897	thiosulfate sulfurtransferase activity
LL042_RS16050	COG0745	RESPONSE REGULATOR receiver
LL042_RS16055	COG1609	Transcriptional regulator
LL042_RS16060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL042_RS16075	COG3866	Pectate lyase
LL042_RS16110	COG0737	Belongs to the 5'-nucleotidase family
LL042_RS16115	COG0456	acetyltransferase
LL042_RS16150	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LL042_RS16160	COG0406	alpha-ribazole phosphatase activity
LL042_RS16160	COG0494	nUDIX hydrolase
LL042_RS16180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LL042_RS16185	COG0306	phosphate transporter
LL042_RS16195	COG1937	Protein conserved in bacteria
LL042_RS16215	COG0671	phosphoesterase, PA-phosphatase related
LL042_RS16265	COG1131	(ABC) transporter
LL042_RS16275	COG4585	Histidine kinase
LL042_RS16280	COG2197	response regulator
LL042_RS16300	COG1846	Transcriptional regulator
LL042_RS16315	COG1252	NADH dehydrogenase
LL042_RS16335	COG0579	oxidoreductase
LL042_RS16340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LL042_RS16360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LL042_RS16360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LL042_RS16365	COG2197	response regulator
LL042_RS16385	COG0513	Belongs to the DEAD box helicase family
LL042_RS16420	COG1643	Atp-dependent helicase
LL042_RS16440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LL042_RS16450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LL042_RS16470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LL042_RS16475	COG0047	phosphoribosylformylglycinamidine synthase activity
LL042_RS16480	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LL042_RS16515	COG2197	response regulator
LL042_RS16525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LL042_RS16540	COG0151	Belongs to the GarS family
LL042_RS16600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LL042_RS16670	COG0438	transferase activity, transferring glycosyl groups
LL042_RS16675	COG0438	transferase activity, transferring glycosyl groups
LL042_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS16720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LL042_RS16830	COG1191	sigma factor activity
LL042_RS16835	COG1191	sigma factor activity
LL042_RS16850	COG0477	Major facilitator Superfamily
LL042_RS16870	COG3467	pyridoxamine 5'-phosphate
LL042_RS16875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LL042_RS16885	COG2205	protein histidine kinase activity
LL042_RS16890	COG0745	RESPONSE REGULATOR receiver
LL042_RS16910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LL042_RS16940	COG0784	Response regulator, receiver
LL042_RS16945	COG0318	PFAM AMP-dependent synthetase and ligase
LL042_RS16950	COG1595	DNA-templated transcription, initiation
LL042_RS16990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL042_RS17005	COG0653	protein targeting
LL042_RS17020	COG0006	proline dipeptidase activity
LL042_RS17040	COG1999	signal sequence binding
LL042_RS17055	COG2837	iron assimilation
LL042_RS17065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LL042_RS17070	COG0561	phosphatase activity
LL042_RS17100	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LL042_RS17115	COG0561	phosphatase activity
LL042_RS17125	COG4988	ABC transporter
LL042_RS17130	COG1294	oxidase, subunit
LL042_RS17135	COG1271	oxidase subunit
LL042_RS17140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LL042_RS17145	COG1609	Transcriptional regulator
LL042_RS17150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LL042_RS17165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LL042_RS17190	COG0662	Cupin 2, conserved barrel domain protein
LL042_RS17195	COG1950	PFAM Membrane protein of
LL042_RS17200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LL042_RS17205	COG0626	cystathionine gamma-synthase activity
LL042_RS17230	COG2814	Major facilitator Superfamily
LL042_RS17255	COG0305	Participates in initiation and elongation during chromosome replication
LL042_RS17265	COG0359	binds to the 23S rRNA
LL042_RS17270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LL042_RS17275	COG0629	single-stranded DNA binding
LL042_RS17280	COG0360	Binds together with S18 to 16S ribosomal RNA
LL042_RS17305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL042_RS17315	COG1260	myo-inositol-1-phosphate synthase
LL042_RS17330	COG0617	tRNA 3'-terminal CCA addition
LL042_RS17350	COG1595	DNA-templated transcription, initiation
LL042_RS17360	COG0492	ferredoxin-NADP+ reductase activity
LL042_RS17365	COG3118	belongs to the thioredoxin family
LL042_RS17380	COG1192	Involved in chromosome partitioning
LL042_RS17385	COG0357	Ribosomal RNA small subunit methyltransferase G
LL042_RS17395	COG0706	membrane insertase activity
LL042_RS17400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LL042_RS17405	COG0594	ribonuclease P activity
LL042_RS17410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LL042_RS17415	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LL042_RS17420	COG0592	DNA-directed DNA polymerase activity
LL042_RS17425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LL042_RS17430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LL042_RS17435	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LL042_RS17440	COG0187	DNA topoisomerase II activity
LL042_RS17445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LL042_RS17480	COG0515	serine threonine protein kinase
LL042_RS17505	COG0705	Rhomboid family
LL042_RS17530	COG3764	Sortase (surface protein transpeptidase)
LL042_RS17535	COG3764	Sortase (surface protein transpeptidase)
LL042_RS17540	COG0515	serine threonine protein kinase
LL042_RS17545	COG0768	penicillin binding
LL042_RS17560	COG1716	ATPase activity
LL042_RS17565	COG1716	ATPase activity
LL042_RS17575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LL042_RS17575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL042_RS17590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL042_RS17595	COG1937	Protein conserved in bacteria
LL042_RS17605	COG1937	Protein conserved in bacteria
LL042_RS17620	COG0577	efflux transmembrane transporter activity
LL042_RS17620	COG1136	(ABC) transporter
LL042_RS17630	COG2197	response regulator
LL042_RS17665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LL042_RS17670	COG2151	metal-sulfur cluster biosynthetic enzyme
LL042_RS17675	COG3396	Phenylacetate-CoA oxygenase
LL042_RS17680	COG3460	Phenylacetate-CoA oxygenase
LL042_RS17685	COG3396	Phenylacetate-CoA oxygenase
LL042_RS17710	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL042_RS17715	COG1309	transcriptional regulator
LL042_RS17720	COG1522	sequence-specific DNA binding
LL042_RS17745	COG0303	'Molybdopterin
LL042_RS17765	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS17765	COG3321	synthase
LL042_RS17765	COG0604	alcohol dehydrogenase
LL042_RS17780	COG0515	serine threonine protein kinase
LL042_RS17785	COG0515	serine threonine protein kinase
LL042_RS17795	COG0022	dehydrogenase e1 component
LL042_RS17800	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL042_RS17845	COG1362	aminopeptidase activity
LL042_RS17850	COG1960	acyl-CoA dehydrogenase activity
LL042_RS17860	COG1741	Belongs to the pirin family
LL042_RS17870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LL042_RS17890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL042_RS17905	COG0583	DNA-binding transcription factor activity
LL042_RS17960	COG0366	Alpha amylase catalytic
LL042_RS17995	COG1278	Cold shock
LL042_RS18005	COG0583	DNA-binding transcription factor activity
LL042_RS18015	COG2367	Beta-lactamase
LL042_RS18025	COG4213	ABC transporter substrate-binding protein
LL042_RS18035	COG2755	lipolytic protein G-D-S-L family
LL042_RS18035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LL042_RS18040	COG1595	DNA-templated transcription, initiation
LL042_RS18045	COG1252	NADH dehydrogenase
LL042_RS18060	COG1720	tRNA m6t6A37 methyltransferase activity
LL042_RS18070	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LL042_RS18110	COG0789	Transcriptional regulator
LL042_RS18115	COG1819	glycosyl
LL042_RS18125	COG3903	Transcriptional regulator
LL042_RS18125	COG3629	intracellular signal transduction
LL042_RS18155	COG0463	Glycosyl transferase, family 2
LL042_RS18180	COG0475	glutathione-regulated potassium exporter activity
LL042_RS18185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LL042_RS18215	COG2197	response regulator
LL042_RS18220	COG4585	Histidine kinase
LL042_RS18240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL042_RS18250	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
LL042_RS18415	COG0717	Belongs to the dCTP deaminase family
LL042_RS18420	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LL042_RS18440	COG0247	lactate metabolic process
LL042_RS18440	COG2181	nitrate reductase activity
LL042_RS18445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LL042_RS18450	COG0443	Heat shock 70 kDa protein
LL042_RS18455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LL042_RS18460	COG0484	heat shock protein binding
LL042_RS18465	COG0789	Transcriptional regulator
LL042_RS18470	COG4213	ABC transporter substrate-binding protein
LL042_RS18500	COG0542	response to heat
LL042_RS18535	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LL042_RS18545	COG2017	converts alpha-aldose to the beta-anomer
LL042_RS18550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LL042_RS18555	COG0191	fructose-bisphosphate aldolase activity
LL042_RS18560	COG0477	Major facilitator Superfamily
LL042_RS18575	COG3844	kynureninase activity
LL042_RS18595	COG4585	Histidine kinase
LL042_RS18600	COG2197	response regulator
LL042_RS18605	COG4585	Histidine kinase
LL042_RS18610	COG2197	response regulator
LL042_RS18620	COG3559	Exporter of polyketide antibiotics
LL042_RS18625	COG1131	(ABC) transporter
LL042_RS18645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LL042_RS18660	COG1802	Transcriptional regulator
LL042_RS18670	COG0693	protein deglycase activity
LL042_RS18685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LL042_RS18695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LL042_RS18700	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LL042_RS18710	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LL042_RS18715	COG1396	sequence-specific DNA binding
LL042_RS18760	COG0701	Predicted permease
LL042_RS18785	COG0604	alcohol dehydrogenase
LL042_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS18785	COG3321	synthase
LL042_RS18800	COG3903	Transcriptional regulator
LL042_RS18800	COG3629	intracellular signal transduction
LL042_RS18925	COG0154	amidase activity
LL042_RS18955	COG3415	Transposase
LL042_RS18955	COG2801	Transposase and inactivated derivatives
LL042_RS18980	COG1408	metallophosphoesterase
LL042_RS19020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL042_RS19030	COG0003	Pfam Anion-transporting ATPase
LL042_RS19055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL042_RS19085	COG0596	Alpha beta hydrolase
LL042_RS19095	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LL042_RS19100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LL042_RS19165	COG1111	helicase
LL042_RS19165	COG1205	dead DEAH box helicase
LL042_RS19170	COG1366	Belongs to the anti-sigma-factor antagonist family
LL042_RS19180	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LL042_RS19190	COG2264	protein methyltransferase activity
LL042_RS19200	COG1754	DNA topoisomerase type I activity
LL042_RS19200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LL042_RS19205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LL042_RS19240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL042_RS19240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL042_RS19280	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS19305	COG0789	Transcriptional regulator
LL042_RS19310	COG0586	Pfam SNARE associated Golgi protein
LL042_RS19320	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LL042_RS19325	COG2027	D-alanyl-D-alanine carboxypeptidase
LL042_RS19335	COG0037	tRNA processing
LL042_RS19350	COG0302	gtp cyclohydrolase
LL042_RS19365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LL042_RS19395	COG0649	NAD binding
LL042_RS19415	COG1660	Displays ATPase and GTPase activities
LL042_RS19435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LL042_RS19440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LL042_RS19450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LL042_RS19470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LL042_RS19495	COG0739	heme binding
LL042_RS19510	COG2205	protein histidine kinase activity
LL042_RS19515	COG0745	RESPONSE REGULATOR receiver
LL042_RS19525	COG1595	DNA-templated transcription, initiation
LL042_RS19530	COG1194	a g-specific adenine glycosylase
LL042_RS19555	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LL042_RS19575	COG0248	Ppx GppA phosphatase
LL042_RS19580	COG1082	Xylose isomerase domain protein TIM barrel
LL042_RS19585	COG1309	transcriptional regulator
LL042_RS19590	COG0129	dihydroxy-acid dehydratase activity
LL042_RS19615	COG0842	Transport permease protein
LL042_RS19615	COG1129	ABC transporter
LL042_RS19625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LL042_RS19640	COG0180	Tryptophanyl-tRNA synthetase
LL042_RS19670	COG0123	including yeast histone deacetylase and acetoin utilization protein
LL042_RS19725	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LL042_RS19730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LL042_RS19735	COG0181	hydroxymethylbilane synthase activity
LL042_RS19740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LL042_RS19740	COG1648	precorrin-2 dehydrogenase activity
LL042_RS19775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LL042_RS19805	COG0113	porphobilinogen synthase activity
LL042_RS19820	COG2814	Major facilitator Superfamily
LL042_RS19820	COG0477	Major facilitator Superfamily
LL042_RS19830	COG2159	amidohydrolase
LL042_RS19835	COG0745	RESPONSE REGULATOR receiver
LL042_RS19840	COG2205	protein histidine kinase activity
LL042_RS19855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL042_RS19860	COG0018	arginyl-trna synthetase
LL042_RS19865	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LL042_RS19885	COG1690	Belongs to the RtcB family
LL042_RS19895	COG1742	UPF0060 membrane protein
LL042_RS19900	COG1846	Transcriptional regulator
LL042_RS19905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL042_RS19920	COG2205	protein histidine kinase activity
LL042_RS19925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL042_RS19930	COG2340	Cysteine-rich secretory protein family
LL042_RS19965	COG2197	response regulator
LL042_RS19970	COG4585	Histidine kinase
LL042_RS19985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LL042_RS19990	COG0406	alpha-ribazole phosphatase activity
LL042_RS20005	COG0785	Cytochrome C biogenesis protein
LL042_RS20010	COG1333	cytochrome c biogenesis protein
LL042_RS20015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LL042_RS20060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LL042_RS20065	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LL042_RS20075	COG0163	prenyltransferase activity
LL042_RS20085	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LL042_RS20100	COG1301	dicarboxylic acid transport
LL042_RS20130	COG1309	transcriptional regulator
LL042_RS20145	COG0183	Belongs to the thiolase family
LL042_RS20155	COG1278	Cold shock
LL042_RS20160	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LL042_RS20170	COG1674	ftsk spoiiie
LL042_RS20245	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LL042_RS20295	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LL042_RS20305	COG3979	chitinase
LL042_RS20325	COG2226	methyltransferase
LL042_RS20355	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL042_RS20360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL042_RS20365	COG0649	NAD binding
LL042_RS20375	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LL042_RS20380	COG1034	ATP synthesis coupled electron transport
LL042_RS20385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LL042_RS20390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL042_RS20395	COG0839	Belongs to the complex I subunit 6 family
LL042_RS20400	COG0713	ATP synthesis coupled electron transport
LL042_RS20405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LL042_RS20415	COG1007	ATP synthesis coupled electron transport
LL042_RS20420	COG0514	ATP-dependent DNA helicase (RecQ)
LL042_RS20475	COG0561	phosphatase activity
LL042_RS20485	COG0142	geranyltranstransferase activity
LL042_RS20495	COG1131	(ABC) transporter
LL042_RS20510	COG0655	NAD(P)H dehydrogenase (quinone) activity
LL042_RS20530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LL042_RS20560	COG3903	Transcriptional regulator
LL042_RS20560	COG3629	intracellular signal transduction
LL042_RS20565	COG0702	epimerase
LL042_RS20570	COG1733	regulation of RNA biosynthetic process
LL042_RS20575	COG1013	pyruvate-flavodoxin oxidoreductase activity
LL042_RS20580	COG0674	pyruvate-flavodoxin oxidoreductase activity
LL042_RS20580	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LL042_RS20600	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL042_RS20605	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL042_RS20610	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL042_RS20615	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LL042_RS20620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LL042_RS20625	COG0839	Belongs to the complex I subunit 6 family
LL042_RS20630	COG0713	ATP synthesis coupled electron transport
LL042_RS20645	COG1007	ATP synthesis coupled electron transport
LL042_RS20650	COG0501	Belongs to the peptidase M48B family
LL042_RS20655	COG3304	Inner membrane component domain
LL042_RS20670	COG2261	transglycosylase associated protein
LL042_RS20675	COG1666	GTP binding
LL042_RS20775	COG0702	epimerase
LL042_RS20795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LL042_RS20800	COG2030	dehydratase
LL042_RS20810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LL042_RS20815	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LL042_RS20820	COG0436	Aminotransferase
LL042_RS20835	COG0250	Participates in transcription elongation, termination and antitermination
LL042_RS20840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LL042_RS20845	COG0081	regulation of translation
LL042_RS20855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LL042_RS20860	COG0222	ribosome binding
LL042_RS20865	COG0085	RNA polymerase activity
LL042_RS20870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LL042_RS20880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LL042_RS20885	COG0049	tRNA binding
LL042_RS20890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LL042_RS20895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LL042_RS20920	COG0667	Aldo Keto reductase
LL042_RS20935	COG2197	response regulator
LL042_RS20940	COG4585	Histidine kinase
LL042_RS20945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LL042_RS20955	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS20990	COG0051	transcription antitermination factor activity, RNA binding
LL042_RS20995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LL042_RS21000	COG0088	Forms part of the polypeptide exit tunnel
LL042_RS21005	COG0089	rRNA binding
LL042_RS21010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LL042_RS21015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LL042_RS21020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LL042_RS21025	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LL042_RS21030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LL042_RS21035	COG0255	Belongs to the universal ribosomal protein uL29 family
LL042_RS21040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LL042_RS21045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LL042_RS21050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LL042_RS21055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LL042_RS21060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LL042_RS21065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LL042_RS21070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LL042_RS21075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LL042_RS21080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LL042_RS21085	COG1841	ribosomal large subunit assembly
LL042_RS21090	COG0200	Binds to the 23S rRNA
LL042_RS21100	COG0563	adenylate kinase activity
LL042_RS21110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LL042_RS21115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LL042_RS21120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LL042_RS21125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LL042_RS21130	COG0202	RNA polymerase activity
LL042_RS21135	COG0203	ribosomal protein L17
LL042_RS21140	COG0101	tRNA pseudouridine synthase activity
LL042_RS21150	COG2843	Capsule synthesis protein
LL042_RS21185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LL042_RS21190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LL042_RS21195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LL042_RS21205	COG1072	(Pantothenic acid kinase))
LL042_RS21215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LL042_RS21220	COG0736	holo-[acyl-carrier-protein] synthase activity
LL042_RS21225	COG1191	sigma factor activity
LL042_RS21240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LL042_RS21250	COG0802	atpase or kinase
LL042_RS21275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LL042_RS21295	COG1609	Transcriptional regulator
LL042_RS21300	COG1316	TRANSCRIPTIONal
LL042_RS21310	COG4941	Belongs to the sigma-70 factor family
LL042_RS21320	COG0726	polysaccharide deacetylase
LL042_RS21325	COG0726	polysaccharide deacetylase
LL042_RS21330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LL042_RS21335	COG0459	protein refolding
LL042_RS21390	COG4221	oxidoreductase activity
LL042_RS21400	COG0583	DNA-binding transcription factor activity
LL042_RS21415	COG1595	DNA-templated transcription, initiation
LL042_RS21425	COG0516	GMP reductase activity
LL042_RS21435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LL042_RS21455	COG0515	serine threonine protein kinase
LL042_RS21460	COG0515	serine threonine protein kinase
LL042_RS21465	COG0515	serine threonine protein kinase
LL042_RS21470	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS21495	COG0519	Catalyzes the synthesis of GMP from XMP
LL042_RS21495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LL042_RS21535	COG2197	response regulator
LL042_RS21555	COG0739	heme binding
LL042_RS21565	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL042_RS21565	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL042_RS21580	COG0714	Associated with various cellular activities
LL042_RS21585	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LL042_RS21590	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LL042_RS21600	COG0045	succinate-CoA ligase (ADP-forming) activity
LL042_RS21630	COG0138	bifunctional purine biosynthesis protein purh
LL042_RS21650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LL042_RS21665	COG0039	L-malate dehydrogenase activity
LL042_RS21670	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS21680	COG0517	IMP dehydrogenase activity
LL042_RS21680	COG4175	Glycine betaine
LL042_RS21685	COG4176	ABC-type proline glycine betaine transport system permease component
LL042_RS21695	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LL042_RS21705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL042_RS21715	COG0754	glutathionylspermidine amidase activity
LL042_RS21720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LL042_RS21730	COG0180	Tryptophanyl-tRNA synthetase
LL042_RS21750	COG0671	phosphoesterase, PA-phosphatase related
LL042_RS21765	COG1295	ribonuclease BN
LL042_RS21770	COG1686	Belongs to the peptidase S11 family
LL042_RS21780	COG1408	metallophosphoesterase
LL042_RS21785	COG1309	transcriptional regulator
LL042_RS21805	COG1053	succinate dehydrogenase
LL042_RS21815	COG2009	succinate dehydrogenase
LL042_RS21825	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LL042_RS21880	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL042_RS21880	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL042_RS21910	COG1216	Glycosyl transferase, family 2
LL042_RS21930	COG1216	Glycosyl transferase, family 2
LL042_RS21945	COG2089	acid synthase
LL042_RS21955	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LL042_RS21955	COG1473	amidohydrolase
LL042_RS21960	COG1744	ABC transporter substrate-binding protein PnrA-like
LL042_RS21965	COG1744	ABC transporter substrate-binding protein PnrA-like
LL042_RS21970	COG3845	ABC transporter
LL042_RS21980	COG1079	Belongs to the binding-protein-dependent transport system permease family
LL042_RS22015	COG2814	Major facilitator Superfamily
LL042_RS22020	COG0583	DNA-binding transcription factor activity
LL042_RS22030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LL042_RS22055	COG2205	protein histidine kinase activity
LL042_RS22060	COG0745	RESPONSE REGULATOR receiver
LL042_RS22065	COG1595	DNA-templated transcription, initiation
LL042_RS22080	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS22085	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS22090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LL042_RS22100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LL042_RS22125	COG4770	biotin carboxylase activity
LL042_RS22135	COG0424	maF-like protein
LL042_RS22145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL042_RS22155	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LL042_RS22165	COG1024	Enoyl-CoA hydratase
LL042_RS22175	COG2986	histidine ammonia-lyase
LL042_RS22200	COG1136	(ABC) transporter
LL042_RS22205	COG1404	Belongs to the peptidase S8 family
LL042_RS22215	COG1064	alcohol dehydrogenase
LL042_RS22225	COG0515	serine threonine protein kinase
LL042_RS22225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LL042_RS22250	COG2255	four-way junction helicase activity
LL042_RS22255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LL042_RS22270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LL042_RS22280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL042_RS22315	COG1331	Highly conserved protein containing a thioredoxin domain
LL042_RS22340	COG1331	Highly conserved protein containing a thioredoxin domain
LL042_RS22355	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LL042_RS22380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LL042_RS22480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LL042_RS22570	COG0436	Aminotransferase
LL042_RS22585	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LL042_RS22600	COG1414	Transcriptional regulator
LL042_RS22605	COG0251	oxidation-reduction process
LL042_RS22610	COG2610	gluconate transmembrane transporter activity
LL042_RS22645	COG2894	cell division
LL042_RS22680	COG2197	response regulator
LL042_RS22745	COG2226	methyltransferase
LL042_RS22750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LL042_RS22755	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LL042_RS22770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LL042_RS22775	COG0450	alkyl hydroperoxide reductase
LL042_RS22790	COG1136	(ABC) transporter
LL042_RS22810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL042_RS22825	COG0114	fumarate hydratase activity
LL042_RS22860	COG2226	methyltransferase
LL042_RS22875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LL042_RS22875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LL042_RS22900	COG0778	Nitroreductase
LL042_RS22905	COG1722	exodeoxyribonuclease VII activity
LL042_RS22910	COG1570	exodeoxyribonuclease VII activity
LL042_RS22915	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LL042_RS22920	COG1940	carbohydrate kinase activity
LL042_RS22930	COG0012	GTP binding
LL042_RS22960	COG1366	Belongs to the anti-sigma-factor antagonist family
LL042_RS22965	COG1366	Belongs to the anti-sigma-factor antagonist family
LL042_RS22970	COG2172	sigma factor antagonist activity
LL042_RS23045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LL042_RS23050	COG1053	succinate dehydrogenase
LL042_RS23070	COG1217	gtp-binding protein TYPA
LL042_RS23075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL042_RS23090	COG0444	Belongs to the ABC transporter superfamily
LL042_RS23095	COG4608	Belongs to the ABC transporter superfamily
LL042_RS23105	COG0601	transmembrane transport
LL042_RS23110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL042_RS23115	COG0444	Belongs to the ABC transporter superfamily
LL042_RS23120	COG4608	Belongs to the ABC transporter superfamily
LL042_RS23135	COG0154	amidase activity
LL042_RS23140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL042_RS23155	COG0477	Major facilitator Superfamily
LL042_RS23195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL042_RS23215	COG0519	Catalyzes the synthesis of GMP from XMP
LL042_RS23220	COG1024	Enoyl-CoA hydratase
LL042_RS23235	COG1595	DNA-templated transcription, initiation
LL042_RS23245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL042_RS23250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LL042_RS23285	COG0598	Magnesium transport protein CorA
LL042_RS23295	COG2814	Major facilitator Superfamily
LL042_RS23305	COG0613	PHP domain protein
LL042_RS23310	COG2095	MarC family integral membrane protein
LL042_RS23320	COG1432	Conserved Protein
LL042_RS23330	COG0513	Belongs to the DEAD box helicase family
LL042_RS23420	COG0210	DNA helicase
LL042_RS23425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL042_RS23430	COG2816	NAD+ diphosphatase activity
LL042_RS23465	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LL042_RS23520	COG3480	Lon protease (S16) C-terminal proteolytic domain
LL042_RS23530	COG1615	UPF0182 protein
LL042_RS23555	COG0753	catalase activity
LL042_RS23565	COG0483	inositol monophosphate 1-phosphatase activity
LL042_RS23575	COG2076	Multidrug Resistance protein
LL042_RS23580	COG1162	GTPase activity
LL042_RS23585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LL042_RS23595	COG2135	peptidase activity
LL042_RS23605	COG1595	DNA-templated transcription, initiation
LL042_RS23610	COG5662	AntiSigma factor
LL042_RS23615	COG2199	diguanylate cyclase activity
LL042_RS23615	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LL042_RS23630	COG0242	peptide deformylase activity
LL042_RS23640	COG2124	cytochrome p450
LL042_RS23655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LL042_RS23680	COG2188	Transcriptional regulator
LL042_RS23685	COG0363	glucosamine-6-phosphate deaminase activity
LL042_RS23700	COG1597	lipid kinase activity
LL042_RS23745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LL042_RS23750	COG0142	geranyltranstransferase activity
LL042_RS23755	COG0456	acetyltransferase
LL042_RS23765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LL042_RS23815	COG4106	trans-aconitate 2-methyltransferase activity
LL042_RS23820	COG1126	abc transporter atp-binding protein
LL042_RS23835	COG0281	malic enzyme
LL042_RS23840	COG0604	alcohol dehydrogenase
LL042_RS23870	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL042_RS23870	COG0567	Dehydrogenase, E1 component
LL042_RS23875	COG2205	protein histidine kinase activity
LL042_RS23880	COG0745	RESPONSE REGULATOR receiver
LL042_RS23885	COG0275	rRNA processing
LL042_RS23890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LL042_RS23955	COG0768	penicillin binding
LL042_RS23960	COG0772	Belongs to the SEDS family
LL042_RS23980	COG3285	dna ligase
LL042_RS23980	COG1793	dna ligase
LL042_RS23985	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LL042_RS23990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL042_RS24005	COG1595	DNA-templated transcription, initiation
LL042_RS24020	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LL042_RS24055	COG1959	2 iron, 2 sulfur cluster binding
LL042_RS24055	COG1295	ribonuclease BN
LL042_RS24060	COG1366	Belongs to the anti-sigma-factor antagonist family
LL042_RS24215	COG3547	Transposase (IS116 IS110 IS902 family)
LL042_RS24230	COG2188	Transcriptional regulator
LL042_RS24240	COG2188	Transcriptional regulator
LL042_RS24310	COG0018	arginyl-trna synthetase
LL042_RS24315	COG0019	diaminopimelate decarboxylase activity
LL042_RS24320	COG0460	homoserine dehydrogenase
LL042_RS24325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LL042_RS24330	COG0083	homoserine kinase activity
LL042_RS24345	COG0254	rRNA binding
LL042_RS24350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LL042_RS24355	COG2890	protein-(glutamine-N5) methyltransferase activity
LL042_RS24365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LL042_RS24370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LL042_RS24375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LL042_RS24390	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LL042_RS24395	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LL042_RS24400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LL042_RS24405	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LL042_RS24410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LL042_RS24415	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LL042_RS24420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LL042_RS24435	COG2197	response regulator
LL042_RS24440	COG4585	Histidine kinase
LL042_RS24465	COG1309	transcriptional regulator
LL042_RS24475	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL042_RS24490	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LL042_RS24525	COG1131	(ABC) transporter
LL042_RS24545	COG0183	Belongs to the thiolase family
LL042_RS24560	COG0745	RESPONSE REGULATOR receiver
LL042_RS24615	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL042_RS24615	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL042_RS24655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LL042_RS24660	COG0280	phosphate acetyltransferase
LL042_RS24660	COG0857	belongs to the CobB CobQ family
LL042_RS24665	COG0205	6-phosphofructokinase activity
LL042_RS24675	COG0395	ABC-type sugar transport system, permease component
LL042_RS24680	COG1175	transmembrane transport
LL042_RS24685	COG1653	transport
LL042_RS24690	COG4565	transcriptional regulatory protein
LL042_RS24695	COG3290	protein histidine kinase activity
LL042_RS24700	COG1301	dicarboxylic acid transport
LL042_RS24705	COG0789	Transcriptional regulator
LL042_RS24720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LL042_RS24725	COG3281	Trehalose synthase
LL042_RS24740	COG0058	SHG alpha-glucan phosphorylase activity
LL042_RS24760	COG1132	(ABC) transporter
LL042_RS24765	COG1132	(ABC) transporter
LL042_RS24770	COG1132	(ABC) transporter
LL042_RS24775	COG1132	(ABC) transporter
LL042_RS24780	COG1131	(ABC) transporter
LL042_RS24790	COG4585	Histidine kinase
LL042_RS24795	COG2197	response regulator
LL042_RS24880	COG0464	growth
LL042_RS24890	COG1674	ftsk spoiiie
LL042_RS24960	COG1760	l-serine dehydratase
LL042_RS24965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LL042_RS24970	COG0509	glycine decarboxylation via glycine cleavage system
LL042_RS24975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LL042_RS24995	COG0747	negative chemotaxis
LL042_RS25000	COG0601	transmembrane transport
LL042_RS25005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL042_RS25010	COG0444	Belongs to the ABC transporter superfamily
LL042_RS25015	COG4608	Belongs to the ABC transporter superfamily
LL042_RS25020	COG2860	membrane
LL042_RS25030	COG1309	transcriptional regulator
LL042_RS25060	COG0482	sulfurtransferase activity
LL042_RS25080	COG0475	glutathione-regulated potassium exporter activity
LL042_RS25090	COG2235	arginine
LL042_RS25095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LL042_RS25105	COG1024	Enoyl-CoA hydratase
LL042_RS25160	COG2755	lipolytic protein G-D-S-L family
LL042_RS25165	COG1122	ATPase activity
LL042_RS25175	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
LL042_RS25180	COG0310	cobalt ion transport
LL042_RS25190	COG0601	transmembrane transport
LL042_RS25195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL042_RS25200	COG0444	Belongs to the ABC transporter superfamily
LL042_RS25205	COG4608	Belongs to the ABC transporter superfamily
LL042_RS25220	COG1653	transport
LL042_RS25235	COG0515	serine threonine protein kinase
LL042_RS25300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL042_RS25310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LL042_RS25320	COG4257	antibiotic catabolic process
LL042_RS25325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LL042_RS25350	COG1653	transport
LL042_RS25355	COG1175	transmembrane transport
LL042_RS25360	COG0395	ABC-type sugar transport system, permease component
LL042_RS25365	COG1940	carbohydrate kinase activity
LL042_RS25370	COG4213	ABC transporter substrate-binding protein
LL042_RS25380	COG4214	carbohydrate transport
LL042_RS25385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LL042_RS25390	COG0531	amino acid
LL042_RS25405	COG1316	TRANSCRIPTIONal
LL042_RS25410	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL042_RS25430	COG1024	Enoyl-CoA hydratase
LL042_RS25430	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL042_RS25435	COG0183	Belongs to the thiolase family
LL042_RS25440	COG1609	Transcriptional regulator
LL042_RS25445	COG3250	beta-galactosidase activity
LL042_RS25455	COG1175	transmembrane transport
LL042_RS25465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LL042_RS25480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LL042_RS25515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL042_RS25520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LL042_RS25545	COG1132	(ABC) transporter
LL042_RS25560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS25585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL042_RS25590	COG2197	response regulator
LL042_RS25595	COG4585	Histidine kinase
LL042_RS25615	COG0318	PFAM AMP-dependent synthetase and ligase
LL042_RS25635	COG0446	pyridine nucleotide-disulphide oxidoreductase
LL042_RS25645	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LL042_RS25650	COG3253	May function as heme-dependent peroxidase
LL042_RS25665	COG3220	belongs to the UPF0276 family
LL042_RS25690	COG0723	plastoquinol--plastocyanin reductase activity
LL042_RS25705	COG0330	HflC and HflK could
LL042_RS25710	COG0659	secondary active sulfate transmembrane transporter activity
LL042_RS25735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LL042_RS25740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LL042_RS25775	COG0745	RESPONSE REGULATOR receiver
LL042_RS25780	COG5002	protein histidine kinase activity
LL042_RS25790	COG2205	protein histidine kinase activity
LL042_RS25795	COG0745	RESPONSE REGULATOR receiver
LL042_RS25815	COG2186	Transcriptional regulator
LL042_RS25825	COG2376	Dihydroxyacetone kinase
LL042_RS25830	COG0698	ribose 5-phosphate isomerase
LL042_RS25835	COG0149	triose-phosphate isomerase activity
LL042_RS25840	COG1082	Xylose isomerase domain protein TIM barrel
LL042_RS25845	COG2084	Dehydrogenase
LL042_RS25855	COG1174	glycine betaine transport
LL042_RS25860	COG1174	glycine betaine transport
LL042_RS25900	COG1309	transcriptional regulator
LL042_RS25920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LL042_RS26005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LL042_RS26010	COG1116	anion transmembrane transporter activity
LL042_RS26035	COG0529	Catalyzes the synthesis of activated sulfate
LL042_RS26040	COG0175	sulfate reduction
LL042_RS26070	COG1960	acyl-CoA dehydrogenase activity
LL042_RS26085	COG1917	Cupin 2, conserved barrel domain protein
LL042_RS26085	COG4977	sequence-specific DNA binding
LL042_RS26145	COG2040	homocysteine
LL042_RS26155	COG0477	Major facilitator Superfamily
LL042_RS26200	COG2755	lipolytic protein G-D-S-L family
LL042_RS26255	COG0277	FAD linked oxidase domain protein
LL042_RS26265	COG5297	Belongs to the glycosyl hydrolase family 6
LL042_RS26270	COG1162	GTPase activity
LL042_RS26295	COG0028	Belongs to the TPP enzyme family
LL042_RS26325	COG1802	Transcriptional regulator
LL042_RS26335	COG3835	regulator
LL042_RS26350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL042_RS26375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LL042_RS26385	COG0438	transferase activity, transferring glycosyl groups
LL042_RS26395	COG1215	transferase activity, transferring glycosyl groups
LL042_RS26425	COG2197	response regulator
LL042_RS26430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LL042_RS26435	COG0318	PFAM AMP-dependent synthetase and ligase
LL042_RS26440	COG3960	tartronate-semialdehyde synthase activity
LL042_RS26455	COG2084	Dehydrogenase
LL042_RS26460	COG3622	Belongs to the hyi family
LL042_RS26480	COG2351	hydroxyisourate hydrolase activity
LL042_RS26565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL042_RS26615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LL042_RS26630	COG1414	Transcriptional regulator
LL042_RS26635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LL042_RS26640	COG4266	Belongs to the allantoicase family
LL042_RS26645	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS26665	COG2197	response regulator
LL042_RS26680	COG2188	Transcriptional regulator
LL042_RS26695	COG1129	ABC transporter
LL042_RS26700	COG1940	carbohydrate kinase activity
LL042_RS26710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LL042_RS26775	COG0142	geranyltranstransferase activity
LL042_RS26780	COG3046	protein related to deoxyribodipyrimidine photolyase
LL042_RS26790	COG0702	epimerase
LL042_RS26795	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS26800	COG1278	Cold shock
LL042_RS26805	COG0513	Belongs to the DEAD box helicase family
LL042_RS26815	COG1278	Cold shock
LL042_RS26820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LL042_RS26825	COG1115	amino acid carrier protein
LL042_RS26845	COG1278	Cold shock
LL042_RS26865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LL042_RS26870	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LL042_RS26890	COG0405	Gamma-glutamyltransferase
LL042_RS26895	COG0542	response to heat
LL042_RS26920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LL042_RS26925	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LL042_RS26935	COG1953	Uracil, thiamine, allantoin
LL042_RS26955	COG4608	Belongs to the ABC transporter superfamily
LL042_RS26960	COG0444	Belongs to the ABC transporter superfamily
LL042_RS26970	COG4166	transmembrane transport
LL042_RS26980	COG3458	cephalosporin-C deacetylase activity
LL042_RS26990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL042_RS27000	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LL042_RS27010	COG0483	inositol monophosphate 1-phosphatase activity
LL042_RS27020	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LL042_RS27030	COG0640	Transcriptional regulator
LL042_RS27050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LL042_RS27060	COG1929	Belongs to the glycerate kinase type-1 family
LL042_RS27075	COG0688	phosphatidylethanolamine metabolic process
LL042_RS27080	COG1960	acyl-CoA dehydrogenase activity
LL042_RS27090	COG2301	Belongs to the HpcH HpaI aldolase family
LL042_RS27095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL042_RS27095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LL042_RS27100	COG0604	alcohol dehydrogenase
LL042_RS27110	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL042_RS27125	COG0596	Alpha beta hydrolase
LL042_RS27145	COG2172	sigma factor antagonist activity
LL042_RS27145	COG2208	phosphoserine phosphatase activity
LL042_RS27145	COG1366	Belongs to the anti-sigma-factor antagonist family
LL042_RS27155	COG2362	D-Aminopeptidase
LL042_RS27160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL042_RS27165	COG0823	Involved in the tonB-independent uptake of proteins
LL042_RS27165	COG1506	peptidase
LL042_RS27165	COG4946	Tricorn protease homolog
LL042_RS27170	COG1619	proteins homologs of microcin C7 resistance protein MccF
LL042_RS27195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL042_RS27210	COG1793	dna ligase
LL042_RS27210	COG3285	dna ligase
LL042_RS27270	COG0488	(ABC) transporter
LL042_RS27285	COG0693	protein deglycase activity
LL042_RS27290	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LL042_RS27360	COG0443	Heat shock 70 kDa protein
LL042_RS27380	COG2154	pterin-4-alpha-carbinolamine dehydratase
LL042_RS27390	COG3401	FG-GAP repeat protein
LL042_RS27405	COG5297	Belongs to the glycosyl hydrolase family 6
LL042_RS27405	COG4733	cellulase activity
LL042_RS27410	COG5297	Belongs to the glycosyl hydrolase family 6
LL042_RS27420	COG4221	oxidoreductase activity
LL042_RS27425	COG0656	L-ascorbic acid biosynthetic process
LL042_RS27445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LL042_RS27460	COG3383	formate dehydrogenase (NAD+) activity
LL042_RS27465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LL042_RS27480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL042_RS27490	COG1940	carbohydrate kinase activity
LL042_RS27495	COG1129	ABC transporter
LL042_RS27500	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL042_RS27505	COG1879	ABC-type sugar transport system periplasmic component
LL042_RS27510	COG0673	inositol 2-dehydrogenase activity
LL042_RS27565	COG2223	nitrite transmembrane transporter activity
LL042_RS27575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LL042_RS27585	COG0045	succinate-CoA ligase (ADP-forming) activity
LL042_RS27600	COG1611	Belongs to the LOG family
LL042_RS27605	COG4221	oxidoreductase activity
LL042_RS27615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LL042_RS27625	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LL042_RS27630	COG0154	amidase activity
LL042_RS27640	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LL042_RS27645	COG2226	methyltransferase
LL042_RS27655	COG2409	Drug exporters of the RND superfamily
LL042_RS27660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL042_RS27670	COG2197	response regulator
LL042_RS27680	COG2133	pyrroloquinoline quinone binding
LL042_RS27685	COG0667	Aldo Keto reductase
LL042_RS27695	COG5001	Diguanylate cyclase
LL042_RS27695	COG3300	MHYT domain
LL042_RS27705	COG0440	acetolactate synthase activity
LL042_RS27710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LL042_RS27715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LL042_RS27720	COG0477	Major facilitator Superfamily
LL042_RS27730	COG2508	Transcriptional regulator
LL042_RS27735	COG0506	proline dehydrogenase activity
LL042_RS27740	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS27745	COG0473	3-isopropylmalate dehydrogenase activity
LL042_RS27750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LL042_RS27755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LL042_RS27770	COG1032	radical SAM domain protein
LL042_RS27775	COG0300	oxidoreductase activity
LL042_RS27780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL042_RS27800	COG2018	Roadblock/LC7 domain
LL042_RS27820	COG2018	Roadblock/LC7 domain
LL042_RS27825	COG5002	protein histidine kinase activity
LL042_RS27835	COG0179	Fumarylacetoacetate (FAA) hydrolase
LL042_RS27840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LL042_RS27875	COG0789	Transcriptional regulator
LL042_RS27885	COG1414	Transcriptional regulator
LL042_RS27890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LL042_RS27895	COG0066	3-isopropylmalate dehydratase activity
LL042_RS27905	COG0776	regulation of translation
LL042_RS27915	COG1920	GTP binding
LL042_RS27925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LL042_RS27930	COG1181	Belongs to the D-alanine--D-alanine ligase family
LL042_RS27950	COG0351	phosphomethylpyrimidine kinase
LL042_RS27955	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LL042_RS27960	COG1461	Dihydroxyacetone kinase
LL042_RS27970	COG0742	ribosomal rna small subunit methyltransferase
LL042_RS27975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LL042_RS27985	COG1399	metal-binding, possibly nucleic acid-binding protein
LL042_RS27990	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LL042_RS27995	COG0571	ribonuclease III activity
LL042_RS28000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LL042_RS28005	COG1733	regulation of RNA biosynthetic process
LL042_RS28010	COG2340	Cysteine-rich secretory protein family
LL042_RS28015	COG1254	Belongs to the acylphosphatase family
LL042_RS28025	COG1196	nuclear chromosome segregation
LL042_RS28030	COG0477	Major facilitator Superfamily
LL042_RS28060	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LL042_RS28080	COG0228	four-way junction DNA binding
LL042_RS28085	COG1837	Belongs to the UPF0109 family
LL042_RS28090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LL042_RS28095	COG0336	Belongs to the RNA methyltransferase TrmD family
LL042_RS28100	COG0335	large ribosomal subunit rRNA binding
LL042_RS28115	COG0681	Belongs to the peptidase S26 family
LL042_RS28120	COG0681	Belongs to the peptidase S26 family
LL042_RS28125	COG0494	nUDIX hydrolase
LL042_RS28135	COG0792	nuclease activity
LL042_RS28150	COG1191	sigma factor activity
LL042_RS28160	COG4942	peptidase
LL042_RS28165	COG0052	Belongs to the universal ribosomal protein uS2 family
LL042_RS28170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LL042_RS28175	COG0528	UMP kinase activity
LL042_RS28180	COG0233	cytoplasmic translational termination
LL042_RS28185	COG0575	Belongs to the CDS family
LL042_RS28195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LL042_RS28205	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LL042_RS28210	COG3842	ATPase activity
LL042_RS28240	COG1136	(ABC) transporter
LL042_RS28245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LL042_RS28255	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS28270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LL042_RS28300	COG3842	ATPase activity
LL042_RS28310	COG1177	transmembrane transport
LL042_RS28315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LL042_RS28335	COG2508	Transcriptional regulator
LL042_RS28340	COG1012	belongs to the aldehyde dehydrogenase family
LL042_RS28355	COG4209	transmembrane transport
LL042_RS28360	COG0395	ABC-type sugar transport system, permease component
LL042_RS28385	COG2197	response regulator
LL042_RS28390	COG4585	Histidine kinase
LL042_RS28400	COG1136	(ABC) transporter
LL042_RS28400	COG4591	ABC-type transport system involved in lipoprotein release permease component
LL042_RS28410	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LL042_RS28415	COG0750	zinc metalloprotease
LL042_RS28420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LL042_RS28435	COG0442	prolyl-tRNA aminoacylation
LL042_RS28455	COG0779	Required for maturation of 30S ribosomal subunits
LL042_RS28470	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LL042_RS28480	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LL042_RS28485	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LL042_RS28500	COG4608	Belongs to the ABC transporter superfamily
LL042_RS28505	COG0444	Belongs to the ABC transporter superfamily
LL042_RS28515	COG0601	transmembrane transport
LL042_RS28520	COG0747	negative chemotaxis
LL042_RS28525	COG0455	bacterial-type flagellum organization
LL042_RS28535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LL042_RS28540	COG1185	polyribonucleotide nucleotidyltransferase activity
LL042_RS28545	COG0612	Peptidase, M16
LL042_RS28550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LL042_RS28570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LL042_RS28575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LL042_RS28605	COG2208	phosphoserine phosphatase activity
LL042_RS28605	COG2770	Histidine kinase
LL042_RS28610	COG0784	Response regulator, receiver
LL042_RS28610	COG2205	protein histidine kinase activity
LL042_RS28620	COG1674	ftsk spoiiie
LL042_RS28630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LL042_RS28640	COG1546	Belongs to the CinA family
LL042_RS28640	COG1058	Belongs to the CinA family
LL042_RS28645	COG1396	sequence-specific DNA binding
LL042_RS28650	COG0783	Belongs to the Dps family
LL042_RS28660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LL042_RS28665	COG1201	RNA secondary structure unwinding
LL042_RS28670	COG1917	Cupin 2, conserved barrel domain protein
LL042_RS28670	COG2207	Transcriptional regulator
LL042_RS28695	COG0628	permease
LL042_RS28700	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LL042_RS28745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LL042_RS28750	COG0765	amino acid transport
LL042_RS28755	COG0765	amino acid transport
LL042_RS28760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL042_RS28765	COG1126	abc transporter atp-binding protein
LL042_RS28770	COG0745	RESPONSE REGULATOR receiver
LL042_RS28775	COG2205	protein histidine kinase activity
LL042_RS28780	COG2358	TRAP transporter, solute receptor (TAXI family
LL042_RS28795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LL042_RS28815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LL042_RS28825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LL042_RS28830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LL042_RS28835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LL042_RS28865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LL042_RS28870	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LL042_RS28875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LL042_RS28910	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LL042_RS28945	COG1802	Transcriptional regulator
LL042_RS28950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LL042_RS28965	COG0187	DNA topoisomerase II activity
LL042_RS28975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL042_RS28980	COG4565	transcriptional regulatory protein
LL042_RS28985	COG3290	protein histidine kinase activity
LL042_RS29010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LL042_RS29015	COG0612	Peptidase, M16
LL042_RS29030	COG1802	Transcriptional regulator
LL042_RS29035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL042_RS29040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL042_RS29040	COG0045	succinate-CoA ligase (ADP-forming) activity
LL042_RS29040	COG1042	CoA-binding domain protein
LL042_RS29055	COG1435	thymidine kinase activity
LL042_RS29075	COG3864	Putative metallopeptidase domain
LL042_RS29130	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LL042_RS29145	COG0745	RESPONSE REGULATOR receiver
LL042_RS29150	COG2205	protein histidine kinase activity
LL042_RS29175	COG0756	dUTP diphosphatase activity
LL042_RS29185	COG4591	ABC-type transport system involved in lipoprotein release permease component
LL042_RS29185	COG1136	(ABC) transporter
LL042_RS29215	COG0569	domain protein
LL042_RS29220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL042_RS29225	COG0531	amino acid
LL042_RS29230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LL042_RS29255	COG2409	Drug exporters of the RND superfamily
LL042_RS29285	COG3291	Pkd domain containing protein
LL042_RS29340	COG0659	secondary active sulfate transmembrane transporter activity
LL042_RS29345	COG0789	Transcriptional regulator
LL042_RS29355	COG0640	Transcriptional regulator
LL042_RS29360	COG2072	flavoprotein involved in K transport
LL042_RS29365	COG0798	PFAM Bile acid sodium symporter
LL042_RS29375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LL042_RS29385	COG0596	Alpha beta hydrolase
LL042_RS29415	COG3693	PFAM glycoside hydrolase, family 10
LL042_RS29420	COG1960	acyl-CoA dehydrogenase activity
LL042_RS29425	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL042_RS29430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LL042_RS29435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LL042_RS29440	COG0583	DNA-binding transcription factor activity
LL042_RS29445	COG0183	Belongs to the thiolase family
LL042_RS29450	COG0477	Major facilitator Superfamily
LL042_RS29465	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LL042_RS29470	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LL042_RS29480	COG1216	Glycosyl transferase, family 2
LL042_RS29490	COG4310	Domain of unknown function (DUF2172)
LL042_RS29505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LL042_RS29535	COG1063	alcohol dehydrogenase
LL042_RS29540	COG0367	asparagine synthase
LL042_RS29560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LL042_RS29580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL042_RS29585	COG0601	transmembrane transport
LL042_RS29590	COG4166	transmembrane transport
LL042_RS29605	COG4948	Mandelate Racemase Muconate Lactonizing
LL042_RS29610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LL042_RS29620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LL042_RS29630	COG2186	Transcriptional regulator
LL042_RS29635	COG1013	pyruvate-flavodoxin oxidoreductase activity
LL042_RS29640	COG0674	pyruvate-flavodoxin oxidoreductase activity
LL042_RS29640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LL042_RS29645	COG0175	sulfate reduction
LL042_RS29665	COG1116	anion transmembrane transporter activity
LL042_RS29690	COG2197	response regulator
LL042_RS29695	COG4585	Histidine kinase
LL042_RS29725	COG1960	acyl-CoA dehydrogenase activity
LL042_RS29735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL042_RS29735	COG2070	2-Nitropropane dioxygenase
LL042_RS29745	COG3321	synthase
LL042_RS29745	COG0604	alcohol dehydrogenase
LL042_RS29760	COG4566	intracellular signal transduction
LL042_RS29765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LL042_RS29780	COG1028	Short-chain dehydrogenase reductase Sdr
LL042_RS29785	COG0402	S-adenosylhomocysteine deaminase activity
LL042_RS29795	COG1021	2,3-dihydroxybenzoate-AMP ligase
LL042_RS29815	COG2375	cellular response to nickel ion
LL042_RS29815	COG1132	(ABC) transporter
LL042_RS29820	COG1132	(ABC) transporter
LL042_RS29825	COG1942	4-Oxalocrotonate Tautomerase
LL042_RS29870	COG1349	DNA-binding transcription factor activity
LL042_RS29875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LL042_RS29885	COG0667	Aldo Keto reductase
LL042_RS29900	COG1914	H( )-stimulated, divalent metal cation uptake system
LL042_RS29905	COG0738	Major facilitator superfamily
LL042_RS29930	COG2188	Transcriptional regulator
LL042_RS29935	COG2182	Extracellular solute-binding protein
LL042_RS29940	COG1175	transmembrane transport
LL042_RS29945	COG0395	ABC-type sugar transport system, permease component
LL042_RS29950	COG1472	Belongs to the glycosyl hydrolase 3 family
LL042_RS29960	COG1799	cell septum assembly
LL042_RS29990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LL042_RS30000	COG2255	four-way junction helicase activity
LL042_RS30010	COG0475	glutathione-regulated potassium exporter activity
LL042_RS30020	COG2235	arginine
LL042_RS30025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LL042_RS30035	COG1024	Enoyl-CoA hydratase
LL042_RS30170	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)