locus-tag	class	description
SGLAU_RS00115	COG0419	ATPase involved in DNA repair
SGLAU_RS00120	COG0420	3'-5' exonuclease activity
SGLAU_RS00195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGLAU_RS00200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGLAU_RS00205	COG1940	carbohydrate kinase activity
SGLAU_RS00220	COG0730	response to heat
SGLAU_RS00225	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SGLAU_RS00230	COG1937	Protein conserved in bacteria
SGLAU_RS00245	COG3547	Transposase (IS116 IS110 IS902 family)
SGLAU_RS00280	COG3293	Transposase
SGLAU_RS00305	COG2226	methyltransferase
SGLAU_RS00335	COG2267	carboxylic ester hydrolase activity
SGLAU_RS00380	COG2197	response regulator
SGLAU_RS00415	COG2770	Histidine kinase
SGLAU_RS00415	COG2208	phosphoserine phosphatase activity
SGLAU_RS00435	COG1733	regulation of RNA biosynthetic process
SGLAU_RS00520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGLAU_RS00530	COG1396	sequence-specific DNA binding
SGLAU_RS00540	COG0243	molybdopterin cofactor binding
SGLAU_RS00565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SGLAU_RS00595	COG2197	response regulator
SGLAU_RS00600	COG4585	Histidine kinase
SGLAU_RS00605	COG2409	Drug exporters of the RND superfamily
SGLAU_RS00640	COG2197	response regulator
SGLAU_RS00645	COG4585	Histidine kinase
SGLAU_RS00660	COG1733	regulation of RNA biosynthetic process
SGLAU_RS00675	COG4221	oxidoreductase activity
SGLAU_RS00745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGLAU_RS00785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SGLAU_RS00795	COG2318	DinB family
SGLAU_RS00850	COG0531	amino acid
SGLAU_RS00870	COG0367	asparagine synthase
SGLAU_RS00880	COG0179	Fumarylacetoacetate (FAA) hydrolase
SGLAU_RS00885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGLAU_RS00915	COG0366	Alpha amylase catalytic
SGLAU_RS00920	COG3833	ABC-type maltose transport systems, permease component
SGLAU_RS00925	COG1175	transmembrane transport
SGLAU_RS00930	COG2182	Extracellular solute-binding protein
SGLAU_RS00935	COG1609	Transcriptional regulator
SGLAU_RS00950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SGLAU_RS00955	COG1131	(ABC) transporter
SGLAU_RS00980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGLAU_RS00985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGLAU_RS00995	COG0561	phosphatase activity
SGLAU_RS01005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGLAU_RS01010	COG0662	Cupin 2, conserved barrel domain protein
SGLAU_RS01035	COG0714	Associated with various cellular activities
SGLAU_RS01055	COG2814	Major facilitator Superfamily
SGLAU_RS01090	COG1132	(ABC) transporter
SGLAU_RS01095	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SGLAU_RS01105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SGLAU_RS01130	COG1834	amidinotransferase
SGLAU_RS01135	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SGLAU_RS01150	COG0667	Aldo Keto reductase
SGLAU_RS01185	COG1834	amidinotransferase
SGLAU_RS01230	COG0596	Alpha beta hydrolase
SGLAU_RS01235	COG1278	Cold shock
SGLAU_RS01325	COG2124	cytochrome p450
SGLAU_RS01345	COG0515	serine threonine protein kinase
SGLAU_RS01345	COG2815	serine threonine protein kinase
SGLAU_RS01350	COG0583	DNA-binding transcription factor activity
SGLAU_RS01370	COG1396	sequence-specific DNA binding
SGLAU_RS01375	COG2326	polyphosphate kinase activity
SGLAU_RS01395	COG1802	Transcriptional regulator
SGLAU_RS01400	COG3938	Belongs to the proline racemase family
SGLAU_RS01415	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGLAU_RS01415	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SGLAU_RS01440	COG0297	glycogen (starch) synthase activity
SGLAU_RS01450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGLAU_RS01455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SGLAU_RS01480	COG0628	permease
SGLAU_RS01545	COG0142	geranyltranstransferase activity
SGLAU_RS01560	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGLAU_RS01580	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SGLAU_RS01600	COG0367	asparagine synthase
SGLAU_RS01620	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SGLAU_RS01640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGLAU_RS01650	COG2188	Transcriptional regulator
SGLAU_RS01655	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SGLAU_RS01675	COG0531	amino acid
SGLAU_RS01685	COG0789	Transcriptional regulator
SGLAU_RS01705	COG5297	Belongs to the glycosyl hydrolase family 6
SGLAU_RS01705	COG4733	cellulase activity
SGLAU_RS01710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SGLAU_RS01715	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SGLAU_RS01725	COG0443	Heat shock 70 kDa protein
SGLAU_RS01730	COG0484	heat shock protein binding
SGLAU_RS01750	COG0346	lactoylglutathione lyase activity
SGLAU_RS01755	COG0640	Transcriptional regulator
SGLAU_RS01775	COG2814	Major facilitator Superfamily
SGLAU_RS01825	COG0477	Major facilitator Superfamily
SGLAU_RS01885	COG1473	amidohydrolase
SGLAU_RS01890	COG1982	Orn Lys Arg decarboxylase major
SGLAU_RS01930	COG0657	acetylesterase activity
SGLAU_RS01945	COG0726	polysaccharide deacetylase
SGLAU_RS01950	COG3226	Transcriptional regulator
SGLAU_RS01965	COG4977	sequence-specific DNA binding
SGLAU_RS01975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGLAU_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS02015	COG4977	sequence-specific DNA binding
SGLAU_RS02030	COG0702	epimerase
SGLAU_RS02040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SGLAU_RS02040	COG2755	lipolytic protein G-D-S-L family
SGLAU_RS02070	COG1473	amidohydrolase
SGLAU_RS02120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGLAU_RS02125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGLAU_RS02130	COG1120	ATPase activity
SGLAU_RS02155	COG1132	(ABC) transporter
SGLAU_RS02160	COG1132	(ABC) transporter
SGLAU_RS02215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SGLAU_RS02245	COG0366	Alpha amylase catalytic
SGLAU_RS02250	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS02255	COG1175	transmembrane transport
SGLAU_RS02280	COG1335	isochorismatase
SGLAU_RS02285	COG4977	sequence-specific DNA binding
SGLAU_RS02290	COG2234	aminopeptidase activity
SGLAU_RS02290	COG4935	Belongs to the peptidase S8 family
SGLAU_RS02305	COG4948	Mandelate Racemase Muconate Lactonizing
SGLAU_RS02320	COG0714	Associated with various cellular activities
SGLAU_RS02325	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SGLAU_RS02345	COG1051	belongs to the nudix hydrolase family
SGLAU_RS02355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGLAU_RS02355	COG0723	plastoquinol--plastocyanin reductase activity
SGLAU_RS02400	COG0009	L-threonylcarbamoyladenylate synthase
SGLAU_RS02435	COG2223	nitrite transmembrane transporter activity
SGLAU_RS02440	COG1793	dna ligase
SGLAU_RS02460	COG0181	hydroxymethylbilane synthase activity
SGLAU_RS02500	COG0366	Alpha amylase catalytic
SGLAU_RS02510	COG3281	Trehalose synthase
SGLAU_RS02515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SGLAU_RS02520	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SGLAU_RS02560	COG1982	Orn Lys Arg decarboxylase major
SGLAU_RS02610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGLAU_RS02645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SGLAU_RS02650	COG0515	serine threonine protein kinase
SGLAU_RS02650	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SGLAU_RS02660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS02675	COG0667	Aldo Keto reductase
SGLAU_RS02690	COG2304	oxidoreductase activity
SGLAU_RS02700	COG0328	RNA-DNA hybrid ribonuclease activity
SGLAU_RS02715	COG0596	Alpha beta hydrolase
SGLAU_RS02720	COG0740	serine-type endopeptidase activity
SGLAU_RS02725	COG0740	serine-type endopeptidase activity
SGLAU_RS02735	COG1191	sigma factor activity
SGLAU_RS02765	COG0842	Transport permease protein
SGLAU_RS02765	COG1716	ATPase activity
SGLAU_RS02765	COG1131	(ABC) transporter
SGLAU_RS02780	COG0667	Aldo Keto reductase
SGLAU_RS02785	COG0583	DNA-binding transcription factor activity
SGLAU_RS02795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGLAU_RS02800	COG0346	lactoylglutathione lyase activity
SGLAU_RS02825	COG1796	DNA polymerase
SGLAU_RS02825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SGLAU_RS02830	COG2409	Drug exporters of the RND superfamily
SGLAU_RS02835	COG1846	Transcriptional regulator
SGLAU_RS02840	COG0702	epimerase
SGLAU_RS02885	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS02930	COG0596	Alpha beta hydrolase
SGLAU_RS02945	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS02950	COG2366	antibiotic biosynthetic process
SGLAU_RS02955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGLAU_RS02985	COG3467	pyridoxamine 5'-phosphate
SGLAU_RS03015	COG2326	polyphosphate kinase activity
SGLAU_RS03020	COG0435	Glutathione S-transferase
SGLAU_RS03025	COG0431	NADPH-dependent FMN reductase
SGLAU_RS03030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGLAU_RS03035	COG1126	abc transporter atp-binding protein
SGLAU_RS03045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGLAU_RS03055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS03075	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SGLAU_RS03080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLAU_RS03115	COG2376	Dihydroxyacetone kinase
SGLAU_RS03120	COG1461	Dihydroxyacetone kinase
SGLAU_RS03150	COG1902	pentaerythritol trinitrate reductase activity
SGLAU_RS03150	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGLAU_RS03165	COG2890	protein-(glutamine-N5) methyltransferase activity
SGLAU_RS03180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SGLAU_RS03195	COG3458	cephalosporin-C deacetylase activity
SGLAU_RS03200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGLAU_RS03215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGLAU_RS03225	COG2066	Belongs to the glutaminase family
SGLAU_RS03240	COG1113	amino acid transport
SGLAU_RS03280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SGLAU_RS03285	COG1993	acr, cog1993
SGLAU_RS03290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SGLAU_RS03295	COG0640	Transcriptional regulator
SGLAU_RS03315	COG1175	transmembrane transport
SGLAU_RS03320	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS03390	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SGLAU_RS03395	COG1501	Belongs to the glycosyl hydrolase 31 family
SGLAU_RS03400	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SGLAU_RS03460	COG3401	FG-GAP repeat protein
SGLAU_RS03485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SGLAU_RS03495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS03500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS03505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS03510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS03535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS03540	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SGLAU_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS03630	COG1215	transferase activity, transferring glycosyl groups
SGLAU_RS03665	COG1349	DNA-binding transcription factor activity
SGLAU_RS03705	COG1309	transcriptional regulator
SGLAU_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS03720	COG1940	carbohydrate kinase activity
SGLAU_RS03730	COG2813	Specifically methylates the guanine in position
SGLAU_RS03740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGLAU_RS03745	COG1349	DNA-binding transcription factor activity
SGLAU_RS03750	COG3387	PFAM Glycoside hydrolase 15-related
SGLAU_RS03805	COG2197	response regulator
SGLAU_RS03810	COG4585	Histidine kinase
SGLAU_RS03835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGLAU_RS03840	COG1660	Displays ATPase and GTPase activities
SGLAU_RS03865	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SGLAU_RS03885	COG0204	Acyl-transferase
SGLAU_RS03910	COG0584	glycerophosphoryl diester phosphodiesterase
SGLAU_RS03930	COG0667	Aldo Keto reductase
SGLAU_RS03955	COG0671	phosphoesterase, PA-phosphatase related
SGLAU_RS03960	COG1309	transcriptional regulator
SGLAU_RS03980	COG0493	'glutamate synthase
SGLAU_RS03985	COG0640	Transcriptional regulator
SGLAU_RS03990	COG1902	pentaerythritol trinitrate reductase activity
SGLAU_RS03995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGLAU_RS04005	COG3509	depolymerase
SGLAU_RS04020	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS04030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SGLAU_RS04035	COG2971	BadF BadG BcrA BcrD
SGLAU_RS04045	COG2706	6-phosphogluconolactonase activity
SGLAU_RS04085	COG2124	cytochrome p450
SGLAU_RS04180	COG2072	flavoprotein involved in K transport
SGLAU_RS04190	COG1132	(ABC) transporter
SGLAU_RS04210	COG1132	(ABC) transporter
SGLAU_RS04220	COG0254	rRNA binding
SGLAU_RS04235	COG1946	Acyl-CoA thioesterase
SGLAU_RS04245	COG2018	Roadblock/LC7 domain
SGLAU_RS04285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SGLAU_RS04310	COG1846	Transcriptional regulator
SGLAU_RS04310	COG1940	carbohydrate kinase activity
SGLAU_RS04330	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS04340	COG3903	Transcriptional regulator
SGLAU_RS04340	COG3629	intracellular signal transduction
SGLAU_RS04345	COG1169	isochorismate synthase
SGLAU_RS04350	COG0367	asparagine synthase
SGLAU_RS04355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGLAU_RS04360	COG1129	ABC transporter
SGLAU_RS04380	COG1132	(ABC) transporter
SGLAU_RS04385	COG2375	cellular response to nickel ion
SGLAU_RS04385	COG1132	(ABC) transporter
SGLAU_RS04395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGLAU_RS04400	COG3433	isochorismatase activity
SGLAU_RS04400	COG2226	methyltransferase
SGLAU_RS04400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGLAU_RS04410	COG3483	tryptophan 2,3-dioxygenase activity
SGLAU_RS04430	COG2197	response regulator
SGLAU_RS04475	COG0475	glutathione-regulated potassium exporter activity
SGLAU_RS04495	COG2192	nodulation
SGLAU_RS04505	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS04510	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS04520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGLAU_RS04530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGLAU_RS04540	COG2070	2-Nitropropane dioxygenase
SGLAU_RS04565	COG2197	response regulator
SGLAU_RS04570	COG2226	methyltransferase
SGLAU_RS04570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGLAU_RS04570	COG3433	isochorismatase activity
SGLAU_RS04580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGLAU_RS04580	COG2226	methyltransferase
SGLAU_RS04580	COG3433	isochorismatase activity
SGLAU_RS04585	COG1021	2,3-dihydroxybenzoate-AMP ligase
SGLAU_RS04620	COG1053	succinate dehydrogenase
SGLAU_RS04620	COG3976	FMN-binding domain protein
SGLAU_RS04635	COG2192	nodulation
SGLAU_RS04650	COG0859	PFAM glycosyl transferase family 9
SGLAU_RS04660	COG0438	transferase activity, transferring glycosyl groups
SGLAU_RS04665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SGLAU_RS04670	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SGLAU_RS04670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SGLAU_RS04675	COG0859	PFAM glycosyl transferase family 9
SGLAU_RS04695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGLAU_RS04715	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS04720	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS04740	COG1793	dna ligase
SGLAU_RS04750	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS04760	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS04770	COG0242	peptide deformylase activity
SGLAU_RS04780	COG3442	glutamine amidotransferase
SGLAU_RS04785	COG0205	6-phosphofructokinase activity
SGLAU_RS04800	COG3275	phosphorelay sensor kinase activity
SGLAU_RS04805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGLAU_RS04815	COG3279	Response regulator of the LytR AlgR family
SGLAU_RS04820	COG1522	sequence-specific DNA binding
SGLAU_RS04825	COG1834	amidinotransferase
SGLAU_RS04830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGLAU_RS04840	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SGLAU_RS04860	COG0829	nickel cation binding
SGLAU_RS04865	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SGLAU_RS04875	COG0804	urea catabolic process
SGLAU_RS04880	COG0832	Belongs to the urease beta subunit family
SGLAU_RS04885	COG0831	urea catabolic process
SGLAU_RS04890	COG1309	transcriptional regulator
SGLAU_RS04935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SGLAU_RS04940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SGLAU_RS04945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SGLAU_RS04950	COG2226	methyltransferase
SGLAU_RS04965	COG1136	(ABC) transporter
SGLAU_RS04970	COG0577	efflux transmembrane transporter activity
SGLAU_RS04970	COG1136	(ABC) transporter
SGLAU_RS04975	COG0456	acetyltransferase
SGLAU_RS04995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SGLAU_RS05000	COG3663	DNA glycosylase
SGLAU_RS05020	COG4585	Histidine kinase
SGLAU_RS05025	COG2197	response regulator
SGLAU_RS05030	COG1940	carbohydrate kinase activity
SGLAU_RS05035	COG2188	Transcriptional regulator
SGLAU_RS05040	COG1595	DNA-templated transcription, initiation
SGLAU_RS05055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGLAU_RS05070	COG0626	cystathionine gamma-synthase activity
SGLAU_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS05095	COG1522	sequence-specific DNA binding
SGLAU_RS05100	COG0419	ATPase involved in DNA repair
SGLAU_RS05105	COG0420	3'-5' exonuclease activity
SGLAU_RS05110	COG2814	Major facilitator Superfamily
SGLAU_RS05115	COG0583	DNA-binding transcription factor activity
SGLAU_RS05120	COG1739	Uncharacterized protein family UPF0029
SGLAU_RS05135	COG1832	CoA-binding protein
SGLAU_RS05165	COG0110	maltose O-acetyltransferase activity
SGLAU_RS05205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGLAU_RS05215	COG0183	Belongs to the thiolase family
SGLAU_RS05235	COG1968	undecaprenyl-diphosphatase activity
SGLAU_RS05245	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SGLAU_RS05250	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS05275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SGLAU_RS05280	COG0747	negative chemotaxis
SGLAU_RS05325	COG0697	spore germination
SGLAU_RS05350	COG1695	Transcriptional regulator
SGLAU_RS05380	COG3507	Belongs to the glycosyl hydrolase 43 family
SGLAU_RS05405	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SGLAU_RS05405	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SGLAU_RS05415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SGLAU_RS05435	COG1716	ATPase activity
SGLAU_RS05455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SGLAU_RS05485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGLAU_RS05495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SGLAU_RS05510	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SGLAU_RS05530	COG2018	Roadblock/LC7 domain
SGLAU_RS05570	COG2814	Major facilitator Superfamily
SGLAU_RS05575	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SGLAU_RS05580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SGLAU_RS05585	COG1984	allophanate hydrolase subunit 2
SGLAU_RS05610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGLAU_RS05615	COG2364	Membrane
SGLAU_RS05625	COG2270	Major facilitator Superfamily
SGLAU_RS05635	COG3030	protein affecting phage T7 exclusion by the F plasmid
SGLAU_RS05640	COG1216	Glycosyl transferase, family 2
SGLAU_RS05660	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS05705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SGLAU_RS05710	COG0140	phosphoribosyl-ATP diphosphatase activity
SGLAU_RS05715	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SGLAU_RS05720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGLAU_RS05720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGLAU_RS05725	COG3201	nicotinamide mononucleotide transporter
SGLAU_RS05740	COG1940	carbohydrate kinase activity
SGLAU_RS05740	COG1846	Transcriptional regulator
SGLAU_RS05745	COG2223	nitrite transmembrane transporter activity
SGLAU_RS05755	COG2233	PERMEase
SGLAU_RS05770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGLAU_RS05790	COG0531	amino acid
SGLAU_RS05810	COG2390	Transcriptional regulator
SGLAU_RS05815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SGLAU_RS05825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SGLAU_RS05840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SGLAU_RS05850	COG1758	RNA polymerase activity
SGLAU_RS05855	COG0194	GDP metabolic process
SGLAU_RS05865	COG0284	orotidine-5'-phosphate decarboxylase activity
SGLAU_RS05870	COG0167	dihydroorotate dehydrogenase activity
SGLAU_RS05875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SGLAU_RS05880	COG0505	Belongs to the CarA family
SGLAU_RS05890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGLAU_RS05895	COG0540	Belongs to the ATCase OTCase family
SGLAU_RS05900	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SGLAU_RS05910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGLAU_RS05915	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SGLAU_RS05920	COG0006	proline dipeptidase activity
SGLAU_RS05930	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGLAU_RS05935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SGLAU_RS05940	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SGLAU_RS05945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SGLAU_RS05950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SGLAU_RS05955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SGLAU_RS05960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SGLAU_RS05980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SGLAU_RS05995	COG0124	histidyl-tRNA synthetase
SGLAU_RS06005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGLAU_RS06010	COG1196	nuclear chromosome segregation
SGLAU_RS06015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SGLAU_RS06020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SGLAU_RS06025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGLAU_RS06030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGLAU_RS06040	COG2255	four-way junction helicase activity
SGLAU_RS06045	COG0632	four-way junction helicase activity
SGLAU_RS06050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SGLAU_RS06055	COG0217	transcriptional regulatory protein
SGLAU_RS06060	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SGLAU_RS06065	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SGLAU_RS06075	COG0438	transferase activity, transferring glycosyl groups
SGLAU_RS06080	COG1560	Kdo2-lipid A biosynthetic process
SGLAU_RS06085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SGLAU_RS06105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SGLAU_RS06120	COG5002	protein histidine kinase activity
SGLAU_RS06120	COG2176	DNA-directed DNA polymerase activity
SGLAU_RS06150	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS06155	COG1175	transmembrane transport
SGLAU_RS06160	COG1653	transport
SGLAU_RS06205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGLAU_RS06265	COG1648	precorrin-2 dehydrogenase activity
SGLAU_RS06265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SGLAU_RS06270	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SGLAU_RS06285	COG1464	Belongs to the NlpA lipoprotein family
SGLAU_RS06290	COG2011	ABC-type metal ion transport system permease component
SGLAU_RS06295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGLAU_RS06330	COG0584	glycerophosphoryl diester phosphodiesterase
SGLAU_RS06335	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS06335	COG0204	Acyl-transferase
SGLAU_RS06355	COG0165	Argininosuccinate lyase
SGLAU_RS06385	COG1438	arginine binding
SGLAU_RS06390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGLAU_RS06395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SGLAU_RS06400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SGLAU_RS06405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SGLAU_RS06440	COG0697	spore germination
SGLAU_RS06450	COG1649	PFAM Uncharacterised BCR, COG1649
SGLAU_RS06480	COG0072	phenylalanine-tRNA ligase activity
SGLAU_RS06480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGLAU_RS06485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SGLAU_RS06490	COG5002	protein histidine kinase activity
SGLAU_RS06495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGLAU_RS06500	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SGLAU_RS06505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SGLAU_RS06510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SGLAU_RS06550	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS06555	COG0174	glutamine synthetase
SGLAU_RS06565	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SGLAU_RS06590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGLAU_RS06640	COG0805	protein transport
SGLAU_RS06645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SGLAU_RS06675	COG0545	Peptidyl-prolyl cis-trans isomerase
SGLAU_RS06680	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SGLAU_RS06690	COG1609	Transcriptional regulator
SGLAU_RS06695	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SGLAU_RS06700	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SGLAU_RS06710	COG4122	O-methyltransferase activity
SGLAU_RS06715	COG1222	aaa ATPase
SGLAU_RS06735	COG0517	IMP dehydrogenase activity
SGLAU_RS06735	COG1994	Peptidase M50
SGLAU_RS06745	COG2197	response regulator
SGLAU_RS06755	COG0747	negative chemotaxis
SGLAU_RS06760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGLAU_RS06765	COG1410	methionine synthase
SGLAU_RS06765	COG0646	methionine synthase
SGLAU_RS06770	COG1414	Transcriptional regulator
SGLAU_RS06775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SGLAU_RS06780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SGLAU_RS06785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SGLAU_RS06795	COG0640	Transcriptional regulator
SGLAU_RS06805	COG0215	cysteine-tRNA ligase activity
SGLAU_RS06820	COG0588	phosphoglycerate mutase activity
SGLAU_RS06825	COG0598	Magnesium transport protein CorA
SGLAU_RS06835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS06840	COG0667	Aldo Keto reductase
SGLAU_RS06870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGLAU_RS06900	COG0601	transmembrane transport
SGLAU_RS06920	COG3281	Trehalose synthase
SGLAU_RS06945	COG0277	FAD linked oxidase domain protein
SGLAU_RS06965	COG2814	Major facilitator Superfamily
SGLAU_RS06995	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS07000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS07005	COG0583	DNA-binding transcription factor activity
SGLAU_RS07015	COG2175	clavaminate synthase activity
SGLAU_RS07020	COG0527	aspartate kinase activity
SGLAU_RS07025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SGLAU_RS07030	COG0697	spore germination
SGLAU_RS07035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGLAU_RS07040	COG4865	methylaspartate mutase activity
SGLAU_RS07050	COG0439	Biotin carboxylase
SGLAU_RS07055	COG0511	ligase activity, forming carbon-carbon bonds
SGLAU_RS07060	COG0825	malonyl-CoA metabolic process
SGLAU_RS07060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SGLAU_RS07095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SGLAU_RS07095	COG2070	2-Nitropropane dioxygenase
SGLAU_RS07115	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGLAU_RS07125	COG0477	Major facilitator Superfamily
SGLAU_RS07200	COG1222	aaa ATPase
SGLAU_RS07230	COG3012	SEC-C Motif Domain Protein
SGLAU_RS07235	COG2186	Transcriptional regulator
SGLAU_RS07240	COG3265	gluconokinase activity
SGLAU_RS07265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SGLAU_RS07270	COG2149	membrane
SGLAU_RS07300	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS07305	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS07310	COG3876	Protein conserved in bacteria
SGLAU_RS07330	COG0789	Transcriptional regulator
SGLAU_RS07350	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS07360	COG0640	Transcriptional regulator
SGLAU_RS07380	COG2851	Citrate transporter
SGLAU_RS07385	COG0243	molybdopterin cofactor binding
SGLAU_RS07390	COG1309	transcriptional regulator
SGLAU_RS07400	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SGLAU_RS07405	COG2188	Transcriptional regulator
SGLAU_RS07460	COG2755	lipolytic protein G-D-S-L family
SGLAU_RS07500	COG3664	PFAM glycoside hydrolase family 39
SGLAU_RS07515	COG1725	Transcriptional regulator
SGLAU_RS07550	COG0587	DNA-directed DNA polymerase activity
SGLAU_RS07585	COG0765	amino acid transport
SGLAU_RS07595	COG1799	cell septum assembly
SGLAU_RS07600	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS07605	COG0477	Major facilitator Superfamily
SGLAU_RS07615	COG0671	phosphoesterase, PA-phosphatase related
SGLAU_RS07640	COG1160	GTP binding
SGLAU_RS07650	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SGLAU_RS07670	COG1187	pseudouridine synthase activity
SGLAU_RS07675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SGLAU_RS07680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SGLAU_RS07695	COG0686	Belongs to the AlaDH PNT family
SGLAU_RS07705	COG0494	nUDIX hydrolase
SGLAU_RS07710	COG0504	CTP synthase activity
SGLAU_RS07715	COG3387	PFAM Glycoside hydrolase 15-related
SGLAU_RS07740	COG0497	DNA recombination
SGLAU_RS07745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SGLAU_RS07765	COG1120	ATPase activity
SGLAU_RS07770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGLAU_RS07775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGLAU_RS07780	COG0647	UMP catabolic process
SGLAU_RS07815	COG2094	Belongs to the DNA glycosylase MPG family
SGLAU_RS07825	COG1881	PFAM PEBP family protein
SGLAU_RS07845	COG1119	ATPase activity
SGLAU_RS07855	COG2197	response regulator
SGLAU_RS07865	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS07870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SGLAU_RS07880	COG1716	ATPase activity
SGLAU_RS07880	COG1131	(ABC) transporter
SGLAU_RS07880	COG0842	Transport permease protein
SGLAU_RS07885	COG0560	Phosphoserine phosphatase
SGLAU_RS07885	COG3830	Belongs to the UPF0237 family
SGLAU_RS07890	COG0588	phosphoglycerate mutase activity
SGLAU_RS07905	COG2186	Transcriptional regulator
SGLAU_RS07935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SGLAU_RS07955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SGLAU_RS07960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGLAU_RS07975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SGLAU_RS07995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGLAU_RS08010	COG3387	PFAM Glycoside hydrolase 15-related
SGLAU_RS08050	COG1024	Enoyl-CoA hydratase
SGLAU_RS08060	COG0488	(ABC) transporter
SGLAU_RS08085	COG0235	Class ii aldolase
SGLAU_RS08100	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SGLAU_RS08105	COG1492	cobalamin metabolic process
SGLAU_RS08125	COG1797	cobyrinic acid a,c-diamide synthase activity
SGLAU_RS08185	COG0765	amino acid transport
SGLAU_RS08190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGLAU_RS08195	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SGLAU_RS08205	COG0456	acetyltransferase
SGLAU_RS08210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SGLAU_RS08215	COG1917	Cupin 2, conserved barrel domain protein
SGLAU_RS08220	COG5285	phytanoyl-CoA dioxygenase
SGLAU_RS08245	COG1414	Transcriptional regulator
SGLAU_RS08260	COG4585	Histidine kinase
SGLAU_RS08265	COG2197	response regulator
SGLAU_RS08270	COG0768	penicillin binding
SGLAU_RS08275	COG1595	DNA-templated transcription, initiation
SGLAU_RS08295	COG4677	pectinesterase activity
SGLAU_RS08305	COG2755	lipolytic protein G-D-S-L family
SGLAU_RS08335	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS08340	COG1175	transmembrane transport
SGLAU_RS08355	COG1802	Transcriptional regulator
SGLAU_RS08360	COG1234	tRNA 3'-trailer cleavage
SGLAU_RS08380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGLAU_RS08385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGLAU_RS08405	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS08410	COG1063	alcohol dehydrogenase
SGLAU_RS08440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGLAU_RS08450	COG2171	N-acyltransferase activity
SGLAU_RS08455	COG2151	metal-sulfur cluster biosynthetic enzyme
SGLAU_RS08460	COG0822	iron-sulfur transferase activity
SGLAU_RS08465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGLAU_RS08470	COG0396	ATPase activity
SGLAU_RS08480	COG0719	Fe-S assembly protein
SGLAU_RS08495	COG2746	aminoglycoside 3-N-acetyltransferase activity
SGLAU_RS08500	COG1131	(ABC) transporter
SGLAU_RS08510	COG1612	heme a metabolic process
SGLAU_RS08525	COG0109	protoheme IX farnesyltransferase activity
SGLAU_RS08535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SGLAU_RS08550	COG0363	glucosamine-6-phosphate deaminase activity
SGLAU_RS08555	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS08560	COG1175	transmembrane transport
SGLAU_RS08565	COG1653	transport
SGLAU_RS08570	COG0366	Alpha amylase catalytic
SGLAU_RS08575	COG1653	transport
SGLAU_RS08580	COG1695	Transcriptional regulator
SGLAU_RS08585	COG1136	(ABC) transporter
SGLAU_RS08600	COG0166	Belongs to the GPI family
SGLAU_RS08610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SGLAU_RS08615	COG0149	triose-phosphate isomerase activity
SGLAU_RS08620	COG0126	phosphoglycerate kinase activity
SGLAU_RS08625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SGLAU_RS08635	COG1481	regulation of sporulation
SGLAU_RS08640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SGLAU_RS08645	COG1660	Displays ATPase and GTPase activities
SGLAU_RS08650	COG0322	excinuclease ABC activity
SGLAU_RS08665	COG1609	Transcriptional regulator
SGLAU_RS08685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SGLAU_RS08695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGLAU_RS08700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGLAU_RS08705	COG0765	amino acid transport
SGLAU_RS08715	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SGLAU_RS08725	COG0477	Major facilitator Superfamily
SGLAU_RS08730	COG0387	Pfam Sodium calcium exchanger
SGLAU_RS08750	COG0556	nucleotide-excision repair
SGLAU_RS08760	COG0584	glycerophosphoryl diester phosphodiesterase
SGLAU_RS08765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGLAU_RS08770	COG2313	pseudouridylate synthase activity
SGLAU_RS08775	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SGLAU_RS08775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SGLAU_RS08780	COG2226	methyltransferase
SGLAU_RS08785	COG0598	Magnesium transport protein CorA
SGLAU_RS08815	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGLAU_RS08820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGLAU_RS08850	COG0402	S-adenosylhomocysteine deaminase activity
SGLAU_RS08895	COG2226	methyltransferase
SGLAU_RS08910	COG0237	dephospho-CoA kinase activity
SGLAU_RS08920	COG0539	negative regulation of cytoplasmic translation
SGLAU_RS08930	COG1643	Atp-dependent helicase
SGLAU_RS08955	COG2050	protein possibly involved in aromatic compounds catabolism
SGLAU_RS08975	COG0411	ABC transporter
SGLAU_RS09005	COG0737	Belongs to the 5'-nucleotidase family
SGLAU_RS09025	COG0287	Prephenate dehydrogenase
SGLAU_RS09025	COG1605	Chorismate mutase
SGLAU_RS09035	COG5640	endopeptidase activity
SGLAU_RS09045	COG2304	oxidoreductase activity
SGLAU_RS09065	COG0070	glutamate synthase
SGLAU_RS09065	COG0069	glutamate synthase activity
SGLAU_RS09065	COG0067	glutamate synthase
SGLAU_RS09095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SGLAU_RS09105	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SGLAU_RS09115	COG0159	tryptophan synthase activity
SGLAU_RS09120	COG0133	tryptophan synthase activity
SGLAU_RS09125	COG0134	indole-3-glycerol-phosphate synthase activity
SGLAU_RS09150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SGLAU_RS09160	COG0107	imidazoleglycerol-phosphate synthase activity
SGLAU_RS09165	COG0251	oxidation-reduction process
SGLAU_RS09170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SGLAU_RS09175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SGLAU_RS09185	COG0131	Imidazoleglycerol-phosphate dehydratase
SGLAU_RS09190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGLAU_RS09195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SGLAU_RS09230	COG1432	Conserved Protein
SGLAU_RS09235	COG0587	DNA-directed DNA polymerase activity
SGLAU_RS09280	COG2153	protein acetylation
SGLAU_RS09290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SGLAU_RS09305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SGLAU_RS09315	COG3599	regulation of cell shape
SGLAU_RS09325	COG1799	cell septum assembly
SGLAU_RS09335	COG1496	oxidoreductase activity
SGLAU_RS09340	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SGLAU_RS09345	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SGLAU_RS09350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SGLAU_RS09360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SGLAU_RS09365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGLAU_RS09370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SGLAU_RS09375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGLAU_RS09380	COG0768	penicillin binding
SGLAU_RS09390	COG0275	rRNA processing
SGLAU_RS09400	COG0714	Associated with various cellular activities
SGLAU_RS09420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGLAU_RS09430	COG1126	abc transporter atp-binding protein
SGLAU_RS09435	COG1511	domain protein
SGLAU_RS09440	COG1309	transcriptional regulator
SGLAU_RS09460	COG0352	thiamine-phosphate diphosphorylase activity
SGLAU_RS09480	COG2022	thiamine diphosphate biosynthetic process
SGLAU_RS09480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGLAU_RS09490	COG2022	thiamine diphosphate biosynthetic process
SGLAU_RS09495	COG2815	serine threonine protein kinase
SGLAU_RS09495	COG0515	serine threonine protein kinase
SGLAU_RS09500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SGLAU_RS09505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SGLAU_RS09510	COG2193	ferroxidase activity
SGLAU_RS09515	COG0243	molybdopterin cofactor binding
SGLAU_RS09520	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SGLAU_RS09535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGLAU_RS09540	COG2197	response regulator
SGLAU_RS09570	COG1940	carbohydrate kinase activity
SGLAU_RS09580	COG0003	Pfam Anion-transporting ATPase
SGLAU_RS09610	COG0534	Mate efflux family protein
SGLAU_RS09655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGLAU_RS09660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SGLAU_RS09665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SGLAU_RS09670	COG0723	plastoquinol--plastocyanin reductase activity
SGLAU_RS09675	COG2010	Cytochrome c
SGLAU_RS09680	COG1845	cytochrome c oxidase, subunit III
SGLAU_RS09690	COG1376	ErfK ybiS ycfS ynhG family protein
SGLAU_RS09700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SGLAU_RS09705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SGLAU_RS09715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGLAU_RS09735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SGLAU_RS09740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SGLAU_RS09740	COG0515	serine threonine protein kinase
SGLAU_RS09745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SGLAU_RS09750	COG2197	response regulator
SGLAU_RS09755	COG4585	Histidine kinase
SGLAU_RS09775	COG2226	methyltransferase
SGLAU_RS09795	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SGLAU_RS09810	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SGLAU_RS09825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SGLAU_RS09830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGLAU_RS09835	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGLAU_RS09850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SGLAU_RS09875	COG0456	acetyltransferase
SGLAU_RS09895	COG0321	lipoyl(octanoyl) transferase activity
SGLAU_RS09900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SGLAU_RS09920	COG0174	glutamine synthetase
SGLAU_RS09960	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS09990	COG1309	transcriptional regulator
SGLAU_RS10010	COG0366	Alpha amylase catalytic
SGLAU_RS10015	COG3833	ABC-type maltose transport systems, permease component
SGLAU_RS10020	COG1175	transmembrane transport
SGLAU_RS10030	COG1609	Transcriptional regulator
SGLAU_RS10040	COG0583	DNA-binding transcription factor activity
SGLAU_RS10045	COG0697	spore germination
SGLAU_RS10050	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SGLAU_RS10060	COG0174	glutamine synthetase
SGLAU_RS10075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SGLAU_RS10075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGLAU_RS10080	COG2814	Major facilitator Superfamily
SGLAU_RS10095	COG0477	Major facilitator Superfamily
SGLAU_RS10100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SGLAU_RS10125	COG1994	Peptidase M50
SGLAU_RS10180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGLAU_RS10185	COG2814	Major facilitator Superfamily
SGLAU_RS10195	COG3540	Alkaline phosphatase
SGLAU_RS10205	COG2259	Doxx family
SGLAU_RS10210	COG1653	transport
SGLAU_RS10280	COG1201	RNA secondary structure unwinding
SGLAU_RS10340	COG1401	restriction endodeoxyribonuclease activity
SGLAU_RS10370	COG3022	response to hydroperoxide
SGLAU_RS10375	COG0800	Aldolase
SGLAU_RS10390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SGLAU_RS10400	COG2030	dehydratase
SGLAU_RS10430	COG0477	Major facilitator Superfamily
SGLAU_RS10485	COG1309	transcriptional regulator
SGLAU_RS10530	COG3845	ABC transporter
SGLAU_RS10565	COG4122	O-methyltransferase activity
SGLAU_RS10585	COG4977	sequence-specific DNA binding
SGLAU_RS10650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SGLAU_RS10700	COG1358	cellular component organization or biogenesis
SGLAU_RS10745	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SGLAU_RS10750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SGLAU_RS10760	COG0477	Major facilitator Superfamily
SGLAU_RS10765	COG1309	transcriptional regulator
SGLAU_RS10780	COG0667	Aldo Keto reductase
SGLAU_RS10785	COG0789	Transcriptional regulator
SGLAU_RS10815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGLAU_RS10820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGLAU_RS10825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGLAU_RS10850	COG1280	lysine exporter protein (LysE YggA)
SGLAU_RS10865	COG1764	response to oxidative stress
SGLAU_RS10870	COG2130	NADP-dependent
SGLAU_RS10885	COG4948	Mandelate Racemase Muconate Lactonizing
SGLAU_RS10900	COG4213	ABC transporter substrate-binding protein
SGLAU_RS10910	COG4214	carbohydrate transport
SGLAU_RS10920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGLAU_RS10925	COG3507	Belongs to the glycosyl hydrolase 43 family
SGLAU_RS10950	COG3973	AAA domain
SGLAU_RS10955	COG3209	COG3209 Rhs family protein
SGLAU_RS10990	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS10995	COG1175	transmembrane transport
SGLAU_RS11035	COG1414	Transcriptional regulator
SGLAU_RS11060	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS11065	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SGLAU_RS11065	COG0825	malonyl-CoA metabolic process
SGLAU_RS11070	COG1404	Belongs to the peptidase S8 family
SGLAU_RS11095	COG1077	Cell shape determining protein MreB Mrl
SGLAU_RS11125	COG1070	Carbohydrate kinase
SGLAU_RS11140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGLAU_RS11145	COG0358	DNA primase activity
SGLAU_RS11155	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SGLAU_RS11165	COG2949	membrane
SGLAU_RS11170	COG0243	molybdopterin cofactor binding
SGLAU_RS11205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SGLAU_RS11210	COG2146	nitrite reductase [NAD(P)H] activity
SGLAU_RS11210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SGLAU_RS11230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGLAU_RS11240	COG0574	Belongs to the PEP-utilizing enzyme family
SGLAU_RS11240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGLAU_RS11245	COG1846	Transcriptional regulator
SGLAU_RS11245	COG1940	carbohydrate kinase activity
SGLAU_RS11250	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SGLAU_RS11280	COG0667	Aldo Keto reductase
SGLAU_RS11290	COG0423	glycine-tRNA ligase activity
SGLAU_RS11300	COG1121	(ABC) transporter
SGLAU_RS11305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGLAU_RS11315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGLAU_RS11320	COG1381	Involved in DNA repair and RecF pathway recombination
SGLAU_RS11335	COG1595	DNA-templated transcription, initiation
SGLAU_RS11345	COG2197	response regulator
SGLAU_RS11350	COG4585	Histidine kinase
SGLAU_RS11360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGLAU_RS11375	COG2723	6-phospho-beta-galactosidase activity
SGLAU_RS11390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SGLAU_RS11410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGLAU_RS11415	COG2315	Protein conserved in bacteria
SGLAU_RS11425	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SGLAU_RS11435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGLAU_RS11445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGLAU_RS11450	COG1234	tRNA 3'-trailer cleavage
SGLAU_RS11455	COG0537	adenosine 5'-monophosphoramidase activity
SGLAU_RS11460	COG4946	Tricorn protease homolog
SGLAU_RS11460	COG0793	Belongs to the peptidase S41A family
SGLAU_RS11480	COG0484	heat shock protein binding
SGLAU_RS11485	COG1420	regulation of RNA biosynthetic process
SGLAU_RS11515	COG0481	GTPase activity
SGLAU_RS11520	COG0268	Binds directly to 16S ribosomal RNA
SGLAU_RS11565	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SGLAU_RS11570	COG1234	tRNA 3'-trailer cleavage
SGLAU_RS11575	COG1555	photosystem II stabilization
SGLAU_RS11580	COG1307	EDD domain protein, DegV family
SGLAU_RS11590	COG0495	leucyl-tRNA aminoacylation
SGLAU_RS11600	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SGLAU_RS11625	COG0588	phosphoglycerate mutase activity
SGLAU_RS11640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SGLAU_RS11655	COG0501	Belongs to the peptidase M48B family
SGLAU_RS11670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SGLAU_RS11680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SGLAU_RS11685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SGLAU_RS11690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SGLAU_RS11695	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SGLAU_RS11700	COG1530	ribonuclease E activity
SGLAU_RS11725	COG0772	Belongs to the SEDS family
SGLAU_RS11745	COG1077	Cell shape determining protein MreB Mrl
SGLAU_RS11750	COG0105	UTP biosynthetic process
SGLAU_RS11760	COG0285	dihydrofolate synthase activity
SGLAU_RS11765	COG0525	valine-tRNA ligase activity
SGLAU_RS11775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SGLAU_RS11780	COG0740	serine-type endopeptidase activity
SGLAU_RS11785	COG0740	serine-type endopeptidase activity
SGLAU_RS11790	COG0544	peptidyl-prolyl cis-trans isomerase activity
SGLAU_RS11810	COG3594	Acyltransferase
SGLAU_RS11825	COG4552	Acetyltransferase involved in intracellular survival and related
SGLAU_RS11840	COG1113	amino acid transport
SGLAU_RS11855	COG1113	amino acid transport
SGLAU_RS11860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SGLAU_RS11865	COG2409	Drug exporters of the RND superfamily
SGLAU_RS11870	COG4585	Histidine kinase
SGLAU_RS11875	COG2197	response regulator
SGLAU_RS11880	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SGLAU_RS11965	COG0697	spore germination
SGLAU_RS11970	COG1846	Transcriptional regulator
SGLAU_RS11975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGLAU_RS12000	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SGLAU_RS12000	COG3291	Pkd domain containing protein
SGLAU_RS12010	COG0668	transmembrane transport
SGLAU_RS12020	COG1486	melibiose metabolic process
SGLAU_RS12035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGLAU_RS12070	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SGLAU_RS12100	COG0629	single-stranded DNA binding
SGLAU_RS12105	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SGLAU_RS12135	COG2304	oxidoreductase activity
SGLAU_RS12160	COG0438	transferase activity, transferring glycosyl groups
SGLAU_RS12165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGLAU_RS12190	COG0438	transferase activity, transferring glycosyl groups
SGLAU_RS12240	COG3962	Belongs to the TPP enzyme family
SGLAU_RS12245	COG3718	enzyme involved in inositol metabolism
SGLAU_RS12255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGLAU_RS12340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SGLAU_RS12370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGLAU_RS12390	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS12395	COG1609	Transcriptional regulator
SGLAU_RS12410	COG1846	Transcriptional regulator
SGLAU_RS12410	COG0456	acetyltransferase
SGLAU_RS12420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGLAU_RS12425	COG1472	Belongs to the glycosyl hydrolase 3 family
SGLAU_RS12460	COG2356	endonuclease I
SGLAU_RS12465	COG0028	Belongs to the TPP enzyme family
SGLAU_RS12475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGLAU_RS12490	COG1946	Acyl-CoA thioesterase
SGLAU_RS12500	COG1309	transcriptional regulator
SGLAU_RS12505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGLAU_RS12520	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS12535	COG0076	glutamate decarboxylase activity
SGLAU_RS12540	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SGLAU_RS12565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGLAU_RS12570	COG0589	response to stress
SGLAU_RS12580	COG4977	sequence-specific DNA binding
SGLAU_RS12585	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SGLAU_RS12610	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS12630	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS12680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS12720	COG3397	chitin binding
SGLAU_RS12780	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS12785	COG4702	Belongs to the UPF0303 family
SGLAU_RS12800	COG0706	membrane insertase activity
SGLAU_RS12835	COG0270	DNA (cytosine-5-)-methyltransferase activity
SGLAU_RS12855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SGLAU_RS12860	COG0596	Alpha beta hydrolase
SGLAU_RS12875	COG0071	Belongs to the small heat shock protein (HSP20) family
SGLAU_RS12895	COG2814	Major facilitator Superfamily
SGLAU_RS12900	COG2733	membrane
SGLAU_RS12915	COG4555	ABC transporter
SGLAU_RS12930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGLAU_RS12965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SGLAU_RS12975	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SGLAU_RS12980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGLAU_RS12985	COG1263	PTS System
SGLAU_RS12990	COG1263	PTS System
SGLAU_RS12995	COG1234	tRNA 3'-trailer cleavage
SGLAU_RS13020	COG1113	amino acid transport
SGLAU_RS13030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SGLAU_RS13040	COG1335	isochorismatase
SGLAU_RS13075	COG0277	FAD linked oxidase domain protein
SGLAU_RS13085	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SGLAU_RS13095	COG1174	glycine betaine transport
SGLAU_RS13105	COG1174	glycine betaine transport
SGLAU_RS13115	COG3480	Lon protease (S16) C-terminal proteolytic domain
SGLAU_RS13145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SGLAU_RS13160	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SGLAU_RS13165	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS13170	COG1175	transmembrane transport
SGLAU_RS13185	COG1678	Uncharacterized ACR, COG1678
SGLAU_RS13190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGLAU_RS13195	COG0776	regulation of translation
SGLAU_RS13205	COG3973	AAA domain
SGLAU_RS13230	COG2223	nitrite transmembrane transporter activity
SGLAU_RS13255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SGLAU_RS13295	COG1609	Transcriptional regulator
SGLAU_RS13300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SGLAU_RS13305	COG0793	Belongs to the peptidase S41A family
SGLAU_RS13315	COG2884	Cell division ATP-binding protein ftsE
SGLAU_RS13330	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SGLAU_RS13335	COG0515	serine threonine protein kinase
SGLAU_RS13340	COG0515	serine threonine protein kinase
SGLAU_RS13355	COG1175	transmembrane transport
SGLAU_RS13360	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS13365	COG0463	Glycosyl transferase, family 2
SGLAU_RS13365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGLAU_RS13370	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGLAU_RS13375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGLAU_RS13390	COG1764	response to oxidative stress
SGLAU_RS13395	COG1846	Transcriptional regulator
SGLAU_RS13420	COG1388	LysM domain
SGLAU_RS13420	COG1134	teichoic acid transport
SGLAU_RS13425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGLAU_RS13430	COG1216	Glycosyl transferase, family 2
SGLAU_RS13455	COG0653	protein targeting
SGLAU_RS13465	COG3214	Protein conserved in bacteria
SGLAU_RS13470	COG2197	response regulator
SGLAU_RS13475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SGLAU_RS13485	COG0823	Involved in the tonB-independent uptake of proteins
SGLAU_RS13490	COG5002	protein histidine kinase activity
SGLAU_RS13495	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS13500	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SGLAU_RS13520	COG0714	Associated with various cellular activities
SGLAU_RS13560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SGLAU_RS13570	COG1482	cell wall glycoprotein biosynthetic process
SGLAU_RS13615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SGLAU_RS13620	COG0778	Nitroreductase
SGLAU_RS13620	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SGLAU_RS13650	COG1316	TRANSCRIPTIONal
SGLAU_RS13655	COG1316	TRANSCRIPTIONal
SGLAU_RS13665	COG0463	Glycosyl transferase, family 2
SGLAU_RS13670	COG1316	TRANSCRIPTIONal
SGLAU_RS13680	COG1316	TRANSCRIPTIONal
SGLAU_RS13690	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SGLAU_RS13725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SGLAU_RS13740	COG2205	protein histidine kinase activity
SGLAU_RS13745	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS13750	COG3104	oligopeptide transport
SGLAU_RS13760	COG1366	Belongs to the anti-sigma-factor antagonist family
SGLAU_RS13765	COG1191	sigma factor activity
SGLAU_RS13775	COG1228	amidohydrolase
SGLAU_RS13785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGLAU_RS13790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SGLAU_RS13840	COG2755	lipolytic protein G-D-S-L family
SGLAU_RS13845	COG0183	Belongs to the thiolase family
SGLAU_RS13875	COG1136	(ABC) transporter
SGLAU_RS13880	COG0577	efflux transmembrane transporter activity
SGLAU_RS13885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SGLAU_RS13890	COG1252	NADH dehydrogenase
SGLAU_RS13920	COG0148	phosphopyruvate hydratase activity
SGLAU_RS13990	COG0577	efflux transmembrane transporter activity
SGLAU_RS13995	COG1136	(ABC) transporter
SGLAU_RS14000	COG2814	Major facilitator Superfamily
SGLAU_RS14035	COG4585	Histidine kinase
SGLAU_RS14050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SGLAU_RS14055	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SGLAU_RS14060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SGLAU_RS14065	COG0193	aminoacyl-tRNA hydrolase activity
SGLAU_RS14080	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SGLAU_RS14090	COG1309	transcriptional regulator
SGLAU_RS14095	COG4106	trans-aconitate 2-methyltransferase activity
SGLAU_RS14105	COG2197	response regulator
SGLAU_RS14115	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SGLAU_RS14155	COG0488	(ABC) transporter
SGLAU_RS14165	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SGLAU_RS14170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SGLAU_RS14180	COG0084	hydrolase, TatD family'
SGLAU_RS14210	COG0310	cobalt ion transport
SGLAU_RS14220	COG1122	ATPase activity
SGLAU_RS14240	COG1764	response to oxidative stress
SGLAU_RS14260	COG0442	prolyl-tRNA aminoacylation
SGLAU_RS14265	COG2409	Drug exporters of the RND superfamily
SGLAU_RS14275	COG0793	Belongs to the peptidase S41A family
SGLAU_RS14275	COG4946	Tricorn protease homolog
SGLAU_RS14285	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS14290	COG2267	carboxylic ester hydrolase activity
SGLAU_RS14295	COG2072	flavoprotein involved in K transport
SGLAU_RS14305	COG0708	Exodeoxyribonuclease III
SGLAU_RS14325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGLAU_RS14330	COG0521	Mo-molybdopterin cofactor biosynthetic process
SGLAU_RS14330	COG0315	cyclic pyranopterin monophosphate synthase activity
SGLAU_RS14335	COG0315	cyclic pyranopterin monophosphate synthase activity
SGLAU_RS14345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SGLAU_RS14350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SGLAU_RS14375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SGLAU_RS14385	COG1970	mechanosensitive ion channel activity
SGLAU_RS14400	COG3191	aminopeptidase activity
SGLAU_RS14425	COG1349	DNA-binding transcription factor activity
SGLAU_RS14430	COG0477	Major facilitator Superfamily
SGLAU_RS14450	COG3384	dioxygenase
SGLAU_RS14455	COG1846	Transcriptional regulator
SGLAU_RS14565	COG0464	growth
SGLAU_RS14600	COG3655	Transcriptional regulator
SGLAU_RS14630	COG0386	Belongs to the glutathione peroxidase family
SGLAU_RS14650	COG1686	Belongs to the peptidase S11 family
SGLAU_RS14715	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGLAU_RS14755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SGLAU_RS14755	COG0515	serine threonine protein kinase
SGLAU_RS14765	COG1309	transcriptional regulator
SGLAU_RS14770	COG1522	sequence-specific DNA binding
SGLAU_RS14775	COG1280	lysine exporter protein (LysE YggA)
SGLAU_RS14780	COG0259	pyridoxamine-phosphate oxidase activity
SGLAU_RS14790	COG2072	flavoprotein involved in K transport
SGLAU_RS14875	COG0596	Alpha beta hydrolase
SGLAU_RS14875	COG2945	thiolester hydrolase activity
SGLAU_RS14885	COG4821	SIS domain
SGLAU_RS14905	COG0259	pyridoxamine-phosphate oxidase activity
SGLAU_RS14920	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS14935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGLAU_RS14965	COG0247	lactate metabolic process
SGLAU_RS14965	COG0277	FAD linked oxidase domain protein
SGLAU_RS14970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SGLAU_RS15010	COG0667	Aldo Keto reductase
SGLAU_RS15035	COG2252	PERMEase
SGLAU_RS15045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGLAU_RS15080	COG2814	Major facilitator Superfamily
SGLAU_RS15090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SGLAU_RS15095	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SGLAU_RS15100	COG1278	Cold shock
SGLAU_RS15135	COG1061	Type III restriction enzyme res subunit
SGLAU_RS15150	COG3973	AAA domain
SGLAU_RS15185	COG1737	Transcriptional regulator
SGLAU_RS15190	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SGLAU_RS15195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGLAU_RS15195	COG1263	PTS System
SGLAU_RS15215	COG0459	protein refolding
SGLAU_RS15220	COG1278	Cold shock
SGLAU_RS15235	COG0463	Glycosyl transferase, family 2
SGLAU_RS15400	COG0270	DNA (cytosine-5-)-methyltransferase activity
SGLAU_RS15425	COG0582	viral genome integration into host DNA
SGLAU_RS15435	COG3842	ATPase activity
SGLAU_RS15460	COG0215	cysteine-tRNA ligase activity
SGLAU_RS15465	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SGLAU_RS15470	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SGLAU_RS15475	COG1329	Transcriptional regulator
SGLAU_RS15490	COG5002	protein histidine kinase activity
SGLAU_RS15500	COG0588	phosphoglycerate mutase activity
SGLAU_RS15505	COG0438	transferase activity, transferring glycosyl groups
SGLAU_RS15510	COG0438	transferase activity, transferring glycosyl groups
SGLAU_RS15530	COG0438	transferase activity, transferring glycosyl groups
SGLAU_RS15555	COG2084	Dehydrogenase
SGLAU_RS15560	COG1733	regulation of RNA biosynthetic process
SGLAU_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS15595	COG3321	synthase
SGLAU_RS15595	COG0604	alcohol dehydrogenase
SGLAU_RS15600	COG4552	Acetyltransferase involved in intracellular survival and related
SGLAU_RS15610	COG1490	D-aminoacyl-tRNA deacylase activity
SGLAU_RS15615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SGLAU_RS15625	COG3485	protocatechuate 3,4-dioxygenase
SGLAU_RS15655	COG2897	thiosulfate sulfurtransferase activity
SGLAU_RS15680	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS15685	COG1609	Transcriptional regulator
SGLAU_RS15690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGLAU_RS15695	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS15740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGLAU_RS15750	COG0737	Belongs to the 5'-nucleotidase family
SGLAU_RS15755	COG0456	acetyltransferase
SGLAU_RS15760	COG1725	Transcriptional regulator
SGLAU_RS15765	COG1131	(ABC) transporter
SGLAU_RS15775	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SGLAU_RS15785	COG0406	alpha-ribazole phosphatase activity
SGLAU_RS15785	COG0494	nUDIX hydrolase
SGLAU_RS15795	COG1937	Protein conserved in bacteria
SGLAU_RS15805	COG0306	phosphate transporter
SGLAU_RS15810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGLAU_RS15830	COG0277	FAD linked oxidase domain protein
SGLAU_RS15835	COG0671	phosphoesterase, PA-phosphatase related
SGLAU_RS15840	COG0741	lytic transglycosylase activity
SGLAU_RS15840	COG1196	nuclear chromosome segregation
SGLAU_RS15840	COG0739	heme binding
SGLAU_RS15905	COG1846	Transcriptional regulator
SGLAU_RS15920	COG1252	NADH dehydrogenase
SGLAU_RS15945	COG0579	oxidoreductase
SGLAU_RS15950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SGLAU_RS15975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGLAU_RS15975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGLAU_RS15990	COG0513	Belongs to the DEAD box helicase family
SGLAU_RS16030	COG1643	Atp-dependent helicase
SGLAU_RS16065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SGLAU_RS16085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGLAU_RS16090	COG0047	phosphoribosylformylglycinamidine synthase activity
SGLAU_RS16095	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGLAU_RS16130	COG2197	response regulator
SGLAU_RS16140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SGLAU_RS16155	COG0151	Belongs to the GarS family
SGLAU_RS16175	COG2197	response regulator
SGLAU_RS16180	COG4585	Histidine kinase
SGLAU_RS16225	COG0433	COG0433 Predicted ATPase
SGLAU_RS16240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SGLAU_RS16275	COG1191	sigma factor activity
SGLAU_RS16280	COG1191	sigma factor activity
SGLAU_RS16305	COG3467	pyridoxamine 5'-phosphate
SGLAU_RS16315	COG0477	Major facilitator Superfamily
SGLAU_RS16320	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SGLAU_RS16330	COG2205	protein histidine kinase activity
SGLAU_RS16335	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS16350	COG1131	(ABC) transporter
SGLAU_RS16375	COG0561	phosphatase activity
SGLAU_RS16380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SGLAU_RS16390	COG2837	iron assimilation
SGLAU_RS16425	COG0006	proline dipeptidase activity
SGLAU_RS16445	COG0653	protein targeting
SGLAU_RS16460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGLAU_RS16475	COG1595	DNA-templated transcription, initiation
SGLAU_RS16480	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS16485	COG2814	Major facilitator Superfamily
SGLAU_RS16490	COG1309	transcriptional regulator
SGLAU_RS16495	COG0784	Response regulator, receiver
SGLAU_RS16515	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SGLAU_RS16525	COG0561	phosphatase activity
SGLAU_RS16530	COG0739	heme binding
SGLAU_RS16530	COG0741	lytic transglycosylase activity
SGLAU_RS16530	COG1196	nuclear chromosome segregation
SGLAU_RS16535	COG4988	ABC transporter
SGLAU_RS16540	COG1294	oxidase, subunit
SGLAU_RS16545	COG1271	oxidase subunit
SGLAU_RS16555	COG2409	Drug exporters of the RND superfamily
SGLAU_RS16560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGLAU_RS16565	COG1609	Transcriptional regulator
SGLAU_RS16580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SGLAU_RS16605	COG0662	Cupin 2, conserved barrel domain protein
SGLAU_RS16610	COG1950	PFAM Membrane protein of
SGLAU_RS16615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGLAU_RS16620	COG0626	cystathionine gamma-synthase activity
SGLAU_RS16640	COG2814	Major facilitator Superfamily
SGLAU_RS16665	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SGLAU_RS16670	COG0305	Participates in initiation and elongation during chromosome replication
SGLAU_RS16680	COG0359	binds to the 23S rRNA
SGLAU_RS16685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGLAU_RS16690	COG0629	single-stranded DNA binding
SGLAU_RS16695	COG0360	Binds together with S18 to 16S ribosomal RNA
SGLAU_RS16720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGLAU_RS16745	COG0617	tRNA 3'-terminal CCA addition
SGLAU_RS16760	COG0515	serine threonine protein kinase
SGLAU_RS16760	COG2815	serine threonine protein kinase
SGLAU_RS16765	COG1595	DNA-templated transcription, initiation
SGLAU_RS16775	COG0492	ferredoxin-NADP+ reductase activity
SGLAU_RS16780	COG3118	belongs to the thioredoxin family
SGLAU_RS16795	COG1192	Involved in chromosome partitioning
SGLAU_RS16800	COG0357	Ribosomal RNA small subunit methyltransferase G
SGLAU_RS16810	COG0706	membrane insertase activity
SGLAU_RS16815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SGLAU_RS16825	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SGLAU_RS16830	COG0592	DNA-directed DNA polymerase activity
SGLAU_RS16835	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SGLAU_RS16840	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGLAU_RS16845	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SGLAU_RS16850	COG0187	DNA topoisomerase II activity
SGLAU_RS16855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGLAU_RS16880	COG0515	serine threonine protein kinase
SGLAU_RS16905	COG0705	Rhomboid family
SGLAU_RS16930	COG3764	Sortase (surface protein transpeptidase)
SGLAU_RS16935	COG3764	Sortase (surface protein transpeptidase)
SGLAU_RS16940	COG0515	serine threonine protein kinase
SGLAU_RS16945	COG0768	penicillin binding
SGLAU_RS16960	COG1716	ATPase activity
SGLAU_RS16965	COG1716	ATPase activity
SGLAU_RS16990	COG2264	protein methyltransferase activity
SGLAU_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS17045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SGLAU_RS17065	COG0189	ligase activity
SGLAU_RS17080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SGLAU_RS17085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGLAU_RS17090	COG3959	Transketolase, thiamine diphosphate binding domain
SGLAU_RS17095	COG3958	Transketolase
SGLAU_RS17100	COG0747	negative chemotaxis
SGLAU_RS17120	COG0655	NAD(P)H dehydrogenase (quinone) activity
SGLAU_RS17150	COG0702	epimerase
SGLAU_RS17165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SGLAU_RS17195	COG1741	Belongs to the pirin family
SGLAU_RS17200	COG0431	NADPH-dependent FMN reductase
SGLAU_RS17230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SGLAU_RS17235	COG2151	metal-sulfur cluster biosynthetic enzyme
SGLAU_RS17240	COG3396	Phenylacetate-CoA oxygenase
SGLAU_RS17245	COG3460	Phenylacetate-CoA oxygenase
SGLAU_RS17250	COG3396	Phenylacetate-CoA oxygenase
SGLAU_RS17275	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGLAU_RS17280	COG1309	transcriptional regulator
SGLAU_RS17290	COG1522	sequence-specific DNA binding
SGLAU_RS17340	COG0604	alcohol dehydrogenase
SGLAU_RS17340	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS17340	COG3321	synthase
SGLAU_RS17355	COG0515	serine threonine protein kinase
SGLAU_RS17360	COG0515	serine threonine protein kinase
SGLAU_RS17375	COG0022	dehydrogenase e1 component
SGLAU_RS17380	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGLAU_RS17390	COG1802	Transcriptional regulator
SGLAU_RS17435	COG1362	aminopeptidase activity
SGLAU_RS17440	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS17455	COG1741	Belongs to the pirin family
SGLAU_RS17470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SGLAU_RS17495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGLAU_RS17510	COG1289	transmembrane transporter activity
SGLAU_RS17520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGLAU_RS17570	COG0366	Alpha amylase catalytic
SGLAU_RS17610	COG0531	amino acid
SGLAU_RS17615	COG4977	sequence-specific DNA binding
SGLAU_RS17630	COG1215	transferase activity, transferring glycosyl groups
SGLAU_RS17650	COG1801	Protein of unknown function DUF72
SGLAU_RS17655	COG1595	DNA-templated transcription, initiation
SGLAU_RS17660	COG1252	NADH dehydrogenase
SGLAU_RS17665	COG2070	2-Nitropropane dioxygenase
SGLAU_RS17675	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SGLAU_RS17675	COG1672	PFAM Archaeal ATPase
SGLAU_RS17690	COG2197	response regulator
SGLAU_RS17695	COG4585	Histidine kinase
SGLAU_RS17700	COG0586	Pfam SNARE associated Golgi protein
SGLAU_RS17765	COG0142	geranyltranstransferase activity
SGLAU_RS17790	COG0717	Belongs to the dCTP deaminase family
SGLAU_RS17850	COG0247	lactate metabolic process
SGLAU_RS17850	COG2181	nitrate reductase activity
SGLAU_RS17855	COG0443	Heat shock 70 kDa protein
SGLAU_RS17860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SGLAU_RS17865	COG0484	heat shock protein binding
SGLAU_RS17870	COG0789	Transcriptional regulator
SGLAU_RS17880	COG4213	ABC transporter substrate-binding protein
SGLAU_RS17910	COG0542	response to heat
SGLAU_RS17935	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SGLAU_RS17950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SGLAU_RS17955	COG0191	fructose-bisphosphate aldolase activity
SGLAU_RS17975	COG3844	kynureninase activity
SGLAU_RS18000	COG4585	Histidine kinase
SGLAU_RS18005	COG2197	response regulator
SGLAU_RS18010	COG4585	Histidine kinase
SGLAU_RS18015	COG2197	response regulator
SGLAU_RS18030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SGLAU_RS18045	COG1802	Transcriptional regulator
SGLAU_RS18050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SGLAU_RS18055	COG0693	protein deglycase activity
SGLAU_RS18075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SGLAU_RS18080	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SGLAU_RS18100	COG1595	DNA-templated transcription, initiation
SGLAU_RS18140	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS18160	COG2319	Wd-40 repeat
SGLAU_RS18160	COG4249	Peptidase C14 caspase catalytic subunit p20
SGLAU_RS18160	COG2319	Wd-40 repeat
SGLAU_RS18160	COG4249	Peptidase C14 caspase catalytic subunit p20
SGLAU_RS18170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SGLAU_RS18200	COG1408	metallophosphoesterase
SGLAU_RS18210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGLAU_RS18220	COG0003	Pfam Anion-transporting ATPase
SGLAU_RS18240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGLAU_RS18255	COG0494	nUDIX hydrolase
SGLAU_RS18265	COG0596	Alpha beta hydrolase
SGLAU_RS18275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SGLAU_RS18280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SGLAU_RS18345	COG1205	dead DEAH box helicase
SGLAU_RS18345	COG1111	helicase
SGLAU_RS18350	COG1366	Belongs to the anti-sigma-factor antagonist family
SGLAU_RS18360	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SGLAU_RS18370	COG2264	protein methyltransferase activity
SGLAU_RS18385	COG1754	DNA topoisomerase type I activity
SGLAU_RS18385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SGLAU_RS18390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SGLAU_RS18395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SGLAU_RS18430	COG3903	Transcriptional regulator
SGLAU_RS18430	COG3629	intracellular signal transduction
SGLAU_RS18435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGLAU_RS18435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGLAU_RS18465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SGLAU_RS18470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SGLAU_RS18475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SGLAU_RS18480	COG0254	rRNA binding
SGLAU_RS18490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGLAU_RS18510	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS18515	COG2318	DinB family
SGLAU_RS18520	COG0789	Transcriptional regulator
SGLAU_RS18525	COG0393	Putative heavy-metal-binding
SGLAU_RS18530	COG0586	Pfam SNARE associated Golgi protein
SGLAU_RS18540	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SGLAU_RS18545	COG2027	D-alanyl-D-alanine carboxypeptidase
SGLAU_RS18555	COG0037	tRNA processing
SGLAU_RS18570	COG0302	gtp cyclohydrolase
SGLAU_RS18585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SGLAU_RS18600	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SGLAU_RS18600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SGLAU_RS18625	COG0649	NAD binding
SGLAU_RS18640	COG2197	response regulator
SGLAU_RS18645	COG1660	Displays ATPase and GTPase activities
SGLAU_RS18670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SGLAU_RS18675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SGLAU_RS18685	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SGLAU_RS18705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SGLAU_RS18735	COG0739	heme binding
SGLAU_RS18745	COG0346	lactoylglutathione lyase activity
SGLAU_RS18750	COG2205	protein histidine kinase activity
SGLAU_RS18755	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS18765	COG1595	DNA-templated transcription, initiation
SGLAU_RS18780	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SGLAU_RS18800	COG0248	Ppx GppA phosphatase
SGLAU_RS18805	COG1082	Xylose isomerase domain protein TIM barrel
SGLAU_RS18815	COG0129	dihydroxy-acid dehydratase activity
SGLAU_RS18825	COG4991	sh3 domain protein
SGLAU_RS18835	COG0842	Transport permease protein
SGLAU_RS18835	COG1129	ABC transporter
SGLAU_RS18845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SGLAU_RS18860	COG0180	Tryptophanyl-tRNA synthetase
SGLAU_RS18880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGLAU_RS18890	COG0123	including yeast histone deacetylase and acetoin utilization protein
SGLAU_RS18935	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SGLAU_RS18940	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SGLAU_RS18945	COG0181	hydroxymethylbilane synthase activity
SGLAU_RS18950	COG1648	precorrin-2 dehydrogenase activity
SGLAU_RS18950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SGLAU_RS18970	COG0113	porphobilinogen synthase activity
SGLAU_RS18985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGLAU_RS18990	COG0018	arginyl-trna synthetase
SGLAU_RS18995	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SGLAU_RS19015	COG1690	Belongs to the RtcB family
SGLAU_RS19035	COG1742	UPF0060 membrane protein
SGLAU_RS19045	COG1733	regulation of RNA biosynthetic process
SGLAU_RS19055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS19075	COG1247	-acetyltransferase
SGLAU_RS19080	COG0640	Transcriptional regulator
SGLAU_RS19090	COG0697	spore germination
SGLAU_RS19105	COG1597	lipid kinase activity
SGLAU_RS19130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SGLAU_RS19185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SGLAU_RS19190	COG0406	alpha-ribazole phosphatase activity
SGLAU_RS19200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SGLAU_RS19205	COG0785	Cytochrome C biogenesis protein
SGLAU_RS19210	COG1333	cytochrome c biogenesis protein
SGLAU_RS19215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SGLAU_RS19245	COG0697	spore germination
SGLAU_RS19255	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SGLAU_RS19265	COG0163	prenyltransferase activity
SGLAU_RS19275	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGLAU_RS19280	COG1573	uracil-dna glycosylase
SGLAU_RS19295	COG1301	dicarboxylic acid transport
SGLAU_RS19300	COG1309	transcriptional regulator
SGLAU_RS19335	COG1278	Cold shock
SGLAU_RS19340	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SGLAU_RS19365	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGLAU_RS19390	COG2226	methyltransferase
SGLAU_RS19425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGLAU_RS19430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGLAU_RS19435	COG0649	NAD binding
SGLAU_RS19445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SGLAU_RS19450	COG1034	ATP synthesis coupled electron transport
SGLAU_RS19455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SGLAU_RS19460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGLAU_RS19465	COG0839	Belongs to the complex I subunit 6 family
SGLAU_RS19470	COG0713	ATP synthesis coupled electron transport
SGLAU_RS19475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGLAU_RS19485	COG1007	ATP synthesis coupled electron transport
SGLAU_RS19495	COG0514	ATP-dependent DNA helicase (RecQ)
SGLAU_RS19510	COG0561	phosphatase activity
SGLAU_RS19515	COG5280	Phage tail tape measure protein TP901
SGLAU_RS19515	COG3953	SLT domain
SGLAU_RS19520	COG0142	geranyltranstransferase activity
SGLAU_RS19560	COG1733	regulation of RNA biosynthetic process
SGLAU_RS19570	COG0702	epimerase
SGLAU_RS19575	COG1733	regulation of RNA biosynthetic process
SGLAU_RS19580	COG1013	pyruvate-flavodoxin oxidoreductase activity
SGLAU_RS19585	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SGLAU_RS19585	COG0674	pyruvate-flavodoxin oxidoreductase activity
SGLAU_RS19605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGLAU_RS19610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGLAU_RS19615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGLAU_RS19620	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SGLAU_RS19625	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGLAU_RS19630	COG0839	Belongs to the complex I subunit 6 family
SGLAU_RS19635	COG0713	ATP synthesis coupled electron transport
SGLAU_RS19640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGLAU_RS19645	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGLAU_RS19650	COG1007	ATP synthesis coupled electron transport
SGLAU_RS19655	COG0501	Belongs to the peptidase M48B family
SGLAU_RS19660	COG3304	Inner membrane component domain
SGLAU_RS19670	COG1666	GTP binding
SGLAU_RS19680	COG3903	Transcriptional regulator
SGLAU_RS19680	COG3629	intracellular signal transduction
SGLAU_RS19685	COG0702	epimerase
SGLAU_RS19705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SGLAU_RS19710	COG2030	dehydratase
SGLAU_RS19725	COG0477	Major facilitator Superfamily
SGLAU_RS19730	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SGLAU_RS19735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGLAU_RS19740	COG0436	Aminotransferase
SGLAU_RS19755	COG0250	Participates in transcription elongation, termination and antitermination
SGLAU_RS19765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SGLAU_RS19770	COG0081	regulation of translation
SGLAU_RS19795	COG0085	RNA polymerase activity
SGLAU_RS19800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SGLAU_RS19835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SGLAU_RS19840	COG0049	tRNA binding
SGLAU_RS19845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGLAU_RS19850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGLAU_RS19880	COG0051	transcription antitermination factor activity, RNA binding
SGLAU_RS19885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SGLAU_RS19890	COG0088	Forms part of the polypeptide exit tunnel
SGLAU_RS19895	COG0089	rRNA binding
SGLAU_RS19900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SGLAU_RS19905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SGLAU_RS19910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SGLAU_RS19915	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SGLAU_RS19920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SGLAU_RS19925	COG0255	Belongs to the universal ribosomal protein uL29 family
SGLAU_RS19930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SGLAU_RS19935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SGLAU_RS19940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SGLAU_RS19945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SGLAU_RS19950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SGLAU_RS19955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SGLAU_RS19960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SGLAU_RS19965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SGLAU_RS19970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SGLAU_RS19975	COG1841	ribosomal large subunit assembly
SGLAU_RS19980	COG0200	Binds to the 23S rRNA
SGLAU_RS19985	COG0201	protein transport
SGLAU_RS19990	COG0563	adenylate kinase activity
SGLAU_RS20000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SGLAU_RS20005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SGLAU_RS20010	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SGLAU_RS20015	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SGLAU_RS20020	COG0202	RNA polymerase activity
SGLAU_RS20025	COG0203	ribosomal protein L17
SGLAU_RS20035	COG0101	tRNA pseudouridine synthase activity
SGLAU_RS20050	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SGLAU_RS20055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SGLAU_RS20060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGLAU_RS20070	COG1072	(Pantothenic acid kinase))
SGLAU_RS20085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGLAU_RS20090	COG0736	holo-[acyl-carrier-protein] synthase activity
SGLAU_RS20100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SGLAU_RS20110	COG0802	atpase or kinase
SGLAU_RS20130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SGLAU_RS20150	COG1175	transmembrane transport
SGLAU_RS20185	COG0726	polysaccharide deacetylase
SGLAU_RS20190	COG0726	polysaccharide deacetylase
SGLAU_RS20195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SGLAU_RS20200	COG0459	protein refolding
SGLAU_RS20210	COG4221	oxidoreductase activity
SGLAU_RS20220	COG0583	DNA-binding transcription factor activity
SGLAU_RS20235	COG1595	DNA-templated transcription, initiation
SGLAU_RS20245	COG0516	GMP reductase activity
SGLAU_RS20260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SGLAU_RS20270	COG2815	serine threonine protein kinase
SGLAU_RS20270	COG0515	serine threonine protein kinase
SGLAU_RS20275	COG0515	serine threonine protein kinase
SGLAU_RS20280	COG0515	serine threonine protein kinase
SGLAU_RS20285	COG0515	serine threonine protein kinase
SGLAU_RS20290	COG0515	serine threonine protein kinase
SGLAU_RS20295	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS20310	COG0519	Catalyzes the synthesis of GMP from XMP
SGLAU_RS20310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGLAU_RS20345	COG2197	response regulator
SGLAU_RS20355	COG0791	NLP P60 protein
SGLAU_RS20390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGLAU_RS20390	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGLAU_RS20405	COG0714	Associated with various cellular activities
SGLAU_RS20410	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SGLAU_RS20415	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SGLAU_RS20430	COG0045	succinate-CoA ligase (ADP-forming) activity
SGLAU_RS20460	COG0138	bifunctional purine biosynthesis protein purh
SGLAU_RS20470	COG2815	serine threonine protein kinase
SGLAU_RS20470	COG0515	serine threonine protein kinase
SGLAU_RS20485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SGLAU_RS20500	COG0039	L-malate dehydrogenase activity
SGLAU_RS20505	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS20515	COG0517	IMP dehydrogenase activity
SGLAU_RS20515	COG4175	Glycine betaine
SGLAU_RS20520	COG4176	ABC-type proline glycine betaine transport system permease component
SGLAU_RS20530	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SGLAU_RS20535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGLAU_RS20540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGLAU_RS20545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGLAU_RS20555	COG0754	glutathionylspermidine amidase activity
SGLAU_RS20560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGLAU_RS20565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SGLAU_RS20570	COG0180	Tryptophanyl-tRNA synthetase
SGLAU_RS20590	COG0671	phosphoesterase, PA-phosphatase related
SGLAU_RS20605	COG1295	ribonuclease BN
SGLAU_RS20610	COG1686	Belongs to the peptidase S11 family
SGLAU_RS20620	COG1408	metallophosphoesterase
SGLAU_RS20655	COG1053	succinate dehydrogenase
SGLAU_RS20665	COG2009	succinate dehydrogenase
SGLAU_RS20675	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SGLAU_RS20705	COG1595	DNA-templated transcription, initiation
SGLAU_RS20720	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGLAU_RS20720	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGLAU_RS20730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SGLAU_RS20755	COG1216	Glycosyl transferase, family 2
SGLAU_RS20770	COG2089	acid synthase
SGLAU_RS20785	COG1473	amidohydrolase
SGLAU_RS20785	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SGLAU_RS20790	COG1744	ABC transporter substrate-binding protein PnrA-like
SGLAU_RS20795	COG1744	ABC transporter substrate-binding protein PnrA-like
SGLAU_RS20800	COG3845	ABC transporter
SGLAU_RS20810	COG1079	Belongs to the binding-protein-dependent transport system permease family
SGLAU_RS20825	COG3344	reverse transcriptase
SGLAU_RS20850	COG2814	Major facilitator Superfamily
SGLAU_RS20855	COG0583	DNA-binding transcription factor activity
SGLAU_RS20865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGLAU_RS20890	COG2205	protein histidine kinase activity
SGLAU_RS20895	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS20900	COG1595	DNA-templated transcription, initiation
SGLAU_RS20915	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS20920	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS20925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SGLAU_RS20935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGLAU_RS20960	COG4770	biotin carboxylase activity
SGLAU_RS20970	COG0424	maF-like protein
SGLAU_RS20985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGLAU_RS20995	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SGLAU_RS21005	COG1024	Enoyl-CoA hydratase
SGLAU_RS21015	COG2986	histidine ammonia-lyase
SGLAU_RS21040	COG1404	Belongs to the peptidase S8 family
SGLAU_RS21050	COG1064	alcohol dehydrogenase
SGLAU_RS21060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SGLAU_RS21090	COG1595	DNA-templated transcription, initiation
SGLAU_RS21100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SGLAU_RS21105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SGLAU_RS21115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SGLAU_RS21135	COG1331	Highly conserved protein containing a thioredoxin domain
SGLAU_RS21165	COG1309	transcriptional regulator
SGLAU_RS21180	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SGLAU_RS21190	COG0436	Aminotransferase
SGLAU_RS21205	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SGLAU_RS21220	COG1414	Transcriptional regulator
SGLAU_RS21225	COG0251	oxidation-reduction process
SGLAU_RS21230	COG2610	gluconate transmembrane transporter activity
SGLAU_RS21265	COG1595	DNA-templated transcription, initiation
SGLAU_RS21295	COG2894	cell division
SGLAU_RS21330	COG2197	response regulator
SGLAU_RS21350	COG2885	chlorophyll binding
SGLAU_RS21365	COG1404	Belongs to the peptidase S8 family
SGLAU_RS21385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGLAU_RS21390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SGLAU_RS21405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGLAU_RS21410	COG0450	alkyl hydroperoxide reductase
SGLAU_RS21425	COG1136	(ABC) transporter
SGLAU_RS21445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGLAU_RS21460	COG0114	fumarate hydratase activity
SGLAU_RS21465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SGLAU_RS21465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SGLAU_RS21490	COG0778	Nitroreductase
SGLAU_RS21495	COG1722	exodeoxyribonuclease VII activity
SGLAU_RS21500	COG1570	exodeoxyribonuclease VII activity
SGLAU_RS21510	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SGLAU_RS21525	COG0012	GTP binding
SGLAU_RS21540	COG0300	oxidoreductase activity
SGLAU_RS21595	COG1053	succinate dehydrogenase
SGLAU_RS21615	COG1217	gtp-binding protein TYPA
SGLAU_RS21620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGLAU_RS21625	COG4166	transmembrane transport
SGLAU_RS21630	COG0601	transmembrane transport
SGLAU_RS21635	COG0444	Belongs to the ABC transporter superfamily
SGLAU_RS21640	COG4608	Belongs to the ABC transporter superfamily
SGLAU_RS21645	COG2318	DinB family
SGLAU_RS21650	COG4608	Belongs to the ABC transporter superfamily
SGLAU_RS21655	COG0444	Belongs to the ABC transporter superfamily
SGLAU_RS21670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGLAU_RS21680	COG0601	transmembrane transport
SGLAU_RS21685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGLAU_RS21695	COG4608	Belongs to the ABC transporter superfamily
SGLAU_RS21710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SGLAU_RS21755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGLAU_RS21765	COG3415	Transposase
SGLAU_RS21765	COG2801	Transposase and inactivated derivatives
SGLAU_RS21770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SGLAU_RS21780	COG0519	Catalyzes the synthesis of GMP from XMP
SGLAU_RS21785	COG1024	Enoyl-CoA hydratase
SGLAU_RS21795	COG1595	DNA-templated transcription, initiation
SGLAU_RS21805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGLAU_RS21810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SGLAU_RS21835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SGLAU_RS21845	COG0598	Magnesium transport protein CorA
SGLAU_RS21865	COG2095	MarC family integral membrane protein
SGLAU_RS21870	COG1432	Conserved Protein
SGLAU_RS21880	COG0513	Belongs to the DEAD box helicase family
SGLAU_RS21955	COG0596	Alpha beta hydrolase
SGLAU_RS21980	COG0210	DNA helicase
SGLAU_RS21985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGLAU_RS21990	COG2816	NAD+ diphosphatase activity
SGLAU_RS22015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SGLAU_RS22070	COG3480	Lon protease (S16) C-terminal proteolytic domain
SGLAU_RS22080	COG1615	UPF0182 protein
SGLAU_RS22105	COG0753	catalase activity
SGLAU_RS22115	COG0483	inositol monophosphate 1-phosphatase activity
SGLAU_RS22125	COG2076	Multidrug Resistance protein
SGLAU_RS22135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGLAU_RS22145	COG2135	peptidase activity
SGLAU_RS22155	COG1595	DNA-templated transcription, initiation
SGLAU_RS22160	COG5662	AntiSigma factor
SGLAU_RS22165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SGLAU_RS22165	COG2199	diguanylate cyclase activity
SGLAU_RS22180	COG0242	peptide deformylase activity
SGLAU_RS22190	COG2124	cytochrome p450
SGLAU_RS22195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGLAU_RS22230	COG2188	Transcriptional regulator
SGLAU_RS22235	COG2182	Extracellular solute-binding protein
SGLAU_RS22240	COG1175	transmembrane transport
SGLAU_RS22245	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS22250	COG1472	Belongs to the glycosyl hydrolase 3 family
SGLAU_RS22255	COG0363	glucosamine-6-phosphate deaminase activity
SGLAU_RS22260	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS22265	COG1309	transcriptional regulator
SGLAU_RS22280	COG1597	lipid kinase activity
SGLAU_RS22310	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SGLAU_RS22320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SGLAU_RS22325	COG0142	geranyltranstransferase activity
SGLAU_RS22360	COG0537	adenosine 5'-monophosphoramidase activity
SGLAU_RS22385	COG4106	trans-aconitate 2-methyltransferase activity
SGLAU_RS22390	COG1126	abc transporter atp-binding protein
SGLAU_RS22405	COG0281	malic enzyme
SGLAU_RS22410	COG0604	alcohol dehydrogenase
SGLAU_RS22450	COG2255	four-way junction helicase activity
SGLAU_RS22460	COG0567	Dehydrogenase, E1 component
SGLAU_RS22460	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGLAU_RS22465	COG2205	protein histidine kinase activity
SGLAU_RS22470	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS22490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SGLAU_RS22550	COG0768	penicillin binding
SGLAU_RS22565	COG2205	protein histidine kinase activity
SGLAU_RS22585	COG3285	dna ligase
SGLAU_RS22585	COG1793	dna ligase
SGLAU_RS22590	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SGLAU_RS22610	COG1733	regulation of RNA biosynthetic process
SGLAU_RS22650	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS22655	COG0018	arginyl-trna synthetase
SGLAU_RS22660	COG0019	diaminopimelate decarboxylase activity
SGLAU_RS22665	COG0460	homoserine dehydrogenase
SGLAU_RS22670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SGLAU_RS22675	COG0083	homoserine kinase activity
SGLAU_RS22695	COG0254	rRNA binding
SGLAU_RS22700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SGLAU_RS22705	COG2890	protein-(glutamine-N5) methyltransferase activity
SGLAU_RS22715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGLAU_RS22720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SGLAU_RS22740	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGLAU_RS22745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SGLAU_RS22750	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGLAU_RS22755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SGLAU_RS22760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SGLAU_RS22765	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SGLAU_RS22770	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SGLAU_RS22785	COG2197	response regulator
SGLAU_RS22790	COG4585	Histidine kinase
SGLAU_RS22825	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGLAU_RS22840	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SGLAU_RS22875	COG1131	(ABC) transporter
SGLAU_RS22895	COG0183	Belongs to the thiolase family
SGLAU_RS22910	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS22915	COG2205	protein histidine kinase activity
SGLAU_RS22975	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGLAU_RS22975	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGLAU_RS23010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SGLAU_RS23015	COG0857	belongs to the CobB CobQ family
SGLAU_RS23015	COG0280	phosphate acetyltransferase
SGLAU_RS23020	COG0205	6-phosphofructokinase activity
SGLAU_RS23030	COG4565	transcriptional regulatory protein
SGLAU_RS23035	COG3290	protein histidine kinase activity
SGLAU_RS23060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SGLAU_RS23065	COG3281	Trehalose synthase
SGLAU_RS23075	COG0366	Alpha amylase catalytic
SGLAU_RS23080	COG0058	SHG alpha-glucan phosphorylase activity
SGLAU_RS23100	COG0366	Alpha amylase catalytic
SGLAU_RS23100	COG1874	Beta-galactosidase
SGLAU_RS23105	COG1132	(ABC) transporter
SGLAU_RS23110	COG1132	(ABC) transporter
SGLAU_RS23115	COG3119	arylsulfatase activity
SGLAU_RS23130	COG1376	ErfK ybiS ycfS ynhG family protein
SGLAU_RS23135	COG1024	Enoyl-CoA hydratase
SGLAU_RS23160	COG1120	ATPase activity
SGLAU_RS23165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SGLAU_RS23175	COG1760	l-serine dehydratase
SGLAU_RS23180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SGLAU_RS23185	COG0509	glycine decarboxylation via glycine cleavage system
SGLAU_RS23190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SGLAU_RS23210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGLAU_RS23225	COG0444	Belongs to the ABC transporter superfamily
SGLAU_RS23230	COG4608	Belongs to the ABC transporter superfamily
SGLAU_RS23235	COG2860	membrane
SGLAU_RS23245	COG2378	regulation of single-species biofilm formation
SGLAU_RS23275	COG0482	sulfurtransferase activity
SGLAU_RS23285	COG1611	Belongs to the LOG family
SGLAU_RS23290	COG4221	oxidoreductase activity
SGLAU_RS23300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGLAU_RS23310	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGLAU_RS23315	COG0154	amidase activity
SGLAU_RS23325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGLAU_RS23330	COG2226	methyltransferase
SGLAU_RS23335	COG2409	Drug exporters of the RND superfamily
SGLAU_RS23340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGLAU_RS23350	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SGLAU_RS23350	COG1672	PFAM Archaeal ATPase
SGLAU_RS23360	COG2133	pyrroloquinoline quinone binding
SGLAU_RS23365	COG0667	Aldo Keto reductase
SGLAU_RS23385	COG0440	acetolactate synthase activity
SGLAU_RS23390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SGLAU_RS23400	COG2508	Transcriptional regulator
SGLAU_RS23405	COG0506	proline dehydrogenase activity
SGLAU_RS23410	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS23415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGLAU_RS23425	COG0473	3-isopropylmalate dehydrogenase activity
SGLAU_RS23430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SGLAU_RS23435	COG0831	urea catabolic process
SGLAU_RS23435	COG0832	Belongs to the urease beta subunit family
SGLAU_RS23440	COG0804	urea catabolic process
SGLAU_RS23445	COG2957	Belongs to the agmatine deiminase family
SGLAU_RS23460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGLAU_RS23480	COG2353	YceI-like domain
SGLAU_RS23485	COG0438	transferase activity, transferring glycosyl groups
SGLAU_RS23490	COG0697	spore germination
SGLAU_RS23495	COG1032	radical SAM domain protein
SGLAU_RS23500	COG0300	oxidoreductase activity
SGLAU_RS23505	COG5492	domain, Protein
SGLAU_RS23510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGLAU_RS23530	COG2018	Roadblock/LC7 domain
SGLAU_RS23550	COG2018	Roadblock/LC7 domain
SGLAU_RS23555	COG5002	protein histidine kinase activity
SGLAU_RS23565	COG0179	Fumarylacetoacetate (FAA) hydrolase
SGLAU_RS23570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SGLAU_RS23605	COG1414	Transcriptional regulator
SGLAU_RS23610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SGLAU_RS23615	COG0066	3-isopropylmalate dehydratase activity
SGLAU_RS23625	COG0776	regulation of translation
SGLAU_RS23635	COG1920	GTP binding
SGLAU_RS23645	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SGLAU_RS23650	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGLAU_RS23670	COG0351	phosphomethylpyrimidine kinase
SGLAU_RS23680	COG1461	Dihydroxyacetone kinase
SGLAU_RS23690	COG0326	Molecular chaperone. Has ATPase activity
SGLAU_RS23700	COG0742	ribosomal rna small subunit methyltransferase
SGLAU_RS23705	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SGLAU_RS23720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SGLAU_RS23725	COG0571	ribonuclease III activity
SGLAU_RS23730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGLAU_RS23735	COG1733	regulation of RNA biosynthetic process
SGLAU_RS23780	COG2340	Cysteine-rich secretory protein family
SGLAU_RS23785	COG1254	Belongs to the acylphosphatase family
SGLAU_RS23795	COG1196	nuclear chromosome segregation
SGLAU_RS23800	COG0477	Major facilitator Superfamily
SGLAU_RS23835	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SGLAU_RS23855	COG0228	four-way junction DNA binding
SGLAU_RS23860	COG1837	Belongs to the UPF0109 family
SGLAU_RS23865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SGLAU_RS23870	COG0336	Belongs to the RNA methyltransferase TrmD family
SGLAU_RS23875	COG0335	large ribosomal subunit rRNA binding
SGLAU_RS23885	COG0681	Belongs to the peptidase S26 family
SGLAU_RS23890	COG0681	Belongs to the peptidase S26 family
SGLAU_RS23895	COG0681	Belongs to the peptidase S26 family
SGLAU_RS23900	COG0494	nUDIX hydrolase
SGLAU_RS23910	COG0792	nuclease activity
SGLAU_RS23925	COG1191	sigma factor activity
SGLAU_RS23940	COG0052	Belongs to the universal ribosomal protein uS2 family
SGLAU_RS23945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SGLAU_RS23950	COG0528	UMP kinase activity
SGLAU_RS23955	COG0233	cytoplasmic translational termination
SGLAU_RS23960	COG0575	Belongs to the CDS family
SGLAU_RS23970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SGLAU_RS23980	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SGLAU_RS23985	COG3842	ATPase activity
SGLAU_RS24015	COG1136	(ABC) transporter
SGLAU_RS24020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SGLAU_RS24030	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS24035	COG1846	Transcriptional regulator
SGLAU_RS24055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGLAU_RS24060	COG0584	glycerophosphoryl diester phosphodiesterase
SGLAU_RS24065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGLAU_RS24080	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS24090	COG3842	ATPase activity
SGLAU_RS24100	COG1177	transmembrane transport
SGLAU_RS24105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGLAU_RS24135	COG2508	Transcriptional regulator
SGLAU_RS24140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGLAU_RS24145	COG1012	belongs to the aldehyde dehydrogenase family
SGLAU_RS24160	COG4209	transmembrane transport
SGLAU_RS24165	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS24200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SGLAU_RS24205	COG0750	zinc metalloprotease
SGLAU_RS24210	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SGLAU_RS24225	COG0442	prolyl-tRNA aminoacylation
SGLAU_RS24245	COG0779	Required for maturation of 30S ribosomal subunits
SGLAU_RS24260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SGLAU_RS24270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SGLAU_RS24275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SGLAU_RS24290	COG0455	bacterial-type flagellum organization
SGLAU_RS24310	COG1404	Belongs to the peptidase S8 family
SGLAU_RS24355	COG1404	Belongs to the peptidase S8 family
SGLAU_RS24370	COG1674	ftsk spoiiie
SGLAU_RS24390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SGLAU_RS24395	COG1185	polyribonucleotide nucleotidyltransferase activity
SGLAU_RS24400	COG0612	Peptidase, M16
SGLAU_RS24405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SGLAU_RS24425	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SGLAU_RS24430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGLAU_RS24435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SGLAU_RS24465	COG2770	Histidine kinase
SGLAU_RS24465	COG2208	phosphoserine phosphatase activity
SGLAU_RS24470	COG0784	Response regulator, receiver
SGLAU_RS24470	COG2205	protein histidine kinase activity
SGLAU_RS24480	COG1674	ftsk spoiiie
SGLAU_RS24490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGLAU_RS24500	COG1546	Belongs to the CinA family
SGLAU_RS24500	COG1058	Belongs to the CinA family
SGLAU_RS24505	COG1396	sequence-specific DNA binding
SGLAU_RS24510	COG0783	Belongs to the Dps family
SGLAU_RS24520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGLAU_RS24525	COG1201	RNA secondary structure unwinding
SGLAU_RS24530	COG1917	Cupin 2, conserved barrel domain protein
SGLAU_RS24530	COG2207	Transcriptional regulator
SGLAU_RS24555	COG0628	permease
SGLAU_RS24560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SGLAU_RS24570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SGLAU_RS24585	COG0765	amino acid transport
SGLAU_RS24590	COG0765	amino acid transport
SGLAU_RS24595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGLAU_RS24600	COG1126	abc transporter atp-binding protein
SGLAU_RS24605	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS24610	COG2205	protein histidine kinase activity
SGLAU_RS24615	COG2358	TRAP transporter, solute receptor (TAXI family
SGLAU_RS24635	COG2197	response regulator
SGLAU_RS24640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGLAU_RS24660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SGLAU_RS24670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SGLAU_RS24675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SGLAU_RS24685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SGLAU_RS24715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SGLAU_RS24720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SGLAU_RS24725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGLAU_RS24740	COG0588	phosphoglycerate mutase activity
SGLAU_RS24760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGLAU_RS24795	COG1802	Transcriptional regulator
SGLAU_RS24800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGLAU_RS24815	COG0187	DNA topoisomerase II activity
SGLAU_RS24825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGLAU_RS24830	COG4565	transcriptional regulatory protein
SGLAU_RS24835	COG3290	protein histidine kinase activity
SGLAU_RS24845	COG0523	cobalamin synthesis protein
SGLAU_RS24850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGLAU_RS24855	COG0612	Peptidase, M16
SGLAU_RS24870	COG1802	Transcriptional regulator
SGLAU_RS24875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGLAU_RS24895	COG1435	thymidine kinase activity
SGLAU_RS24925	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SGLAU_RS24935	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS24940	COG2205	protein histidine kinase activity
SGLAU_RS24965	COG0756	dUTP diphosphatase activity
SGLAU_RS24990	COG0569	domain protein
SGLAU_RS24995	COG0531	amino acid
SGLAU_RS25000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGLAU_RS25035	COG1940	carbohydrate kinase activity
SGLAU_RS25085	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SGLAU_RS25090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGLAU_RS25105	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SGLAU_RS25125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGLAU_RS25135	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS25145	COG4552	Acetyltransferase involved in intracellular survival and related
SGLAU_RS25170	COG0702	epimerase
SGLAU_RS25220	COG1799	cell septum assembly
SGLAU_RS25250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SGLAU_RS25260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SGLAU_RS25265	COG0531	amino acid
SGLAU_RS25275	COG1024	Enoyl-CoA hydratase
SGLAU_RS25280	COG1902	pentaerythritol trinitrate reductase activity
SGLAU_RS25320	COG1366	Belongs to the anti-sigma-factor antagonist family
SGLAU_RS25325	COG1366	Belongs to the anti-sigma-factor antagonist family
SGLAU_RS25330	COG2172	sigma factor antagonist activity
SGLAU_RS25355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGLAU_RS25360	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SGLAU_RS25370	COG1653	transport
SGLAU_RS25375	COG1175	transmembrane transport
SGLAU_RS25380	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS25385	COG1940	carbohydrate kinase activity
SGLAU_RS25390	COG4213	ABC transporter substrate-binding protein
SGLAU_RS25400	COG4214	carbohydrate transport
SGLAU_RS25405	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SGLAU_RS25410	COG0531	amino acid
SGLAU_RS25430	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGLAU_RS25430	COG1024	Enoyl-CoA hydratase
SGLAU_RS25435	COG0183	Belongs to the thiolase family
SGLAU_RS25440	COG1609	Transcriptional regulator
SGLAU_RS25445	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SGLAU_RS25460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SGLAU_RS25475	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGLAU_RS25490	COG3253	May function as heme-dependent peroxidase
SGLAU_RS25505	COG2208	phosphoserine phosphatase activity
SGLAU_RS25505	COG2770	Histidine kinase
SGLAU_RS25510	COG0596	Alpha beta hydrolase
SGLAU_RS25545	COG3220	belongs to the UPF0276 family
SGLAU_RS25565	COG4152	abc transporter atp-binding protein
SGLAU_RS25590	COG0330	HflC and HflK could
SGLAU_RS25620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SGLAU_RS25625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SGLAU_RS25630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGLAU_RS25635	COG0475	glutathione-regulated potassium exporter activity
SGLAU_RS25645	COG2205	protein histidine kinase activity
SGLAU_RS25650	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS25680	COG1174	glycine betaine transport
SGLAU_RS25685	COG1174	glycine betaine transport
SGLAU_RS25700	COG2018	Roadblock/LC7 domain
SGLAU_RS25705	COG5002	protein histidine kinase activity
SGLAU_RS25720	COG1404	Belongs to the peptidase S8 family
SGLAU_RS25725	COG1309	transcriptional regulator
SGLAU_RS25750	COG0504	CTP synthase activity
SGLAU_RS25755	COG0583	DNA-binding transcription factor activity
SGLAU_RS25830	COG1175	transmembrane transport
SGLAU_RS25870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLAU_RS25875	COG1116	anion transmembrane transporter activity
SGLAU_RS25895	COG0529	Catalyzes the synthesis of activated sulfate
SGLAU_RS25900	COG0175	sulfate reduction
SGLAU_RS25930	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS25940	COG2207	Transcriptional regulator
SGLAU_RS25965	COG1309	transcriptional regulator
SGLAU_RS25970	COG0477	Major facilitator Superfamily
SGLAU_RS25975	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SGLAU_RS25980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGLAU_RS25985	COG2329	Antibiotic biosynthesis monooxygenase
SGLAU_RS25995	COG0662	Cupin 2, conserved barrel domain protein
SGLAU_RS26000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGLAU_RS26005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGLAU_RS26010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGLAU_RS26015	COG2226	methyltransferase
SGLAU_RS26015	COG2867	negative regulation of translational initiation
SGLAU_RS26020	COG2226	methyltransferase
SGLAU_RS26020	COG2867	negative regulation of translational initiation
SGLAU_RS26025	COG2345	Transcriptional regulator
SGLAU_RS26065	COG2040	homocysteine
SGLAU_RS26090	COG5006	permease, DMT superfamily
SGLAU_RS26115	COG0277	FAD linked oxidase domain protein
SGLAU_RS26130	COG1162	GTPase activity
SGLAU_RS26140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGLAU_RS26165	COG0028	Belongs to the TPP enzyme family
SGLAU_RS26195	COG1802	Transcriptional regulator
SGLAU_RS26205	COG3835	regulator
SGLAU_RS26210	COG2252	PERMEase
SGLAU_RS26220	COG0726	polysaccharide deacetylase
SGLAU_RS26245	COG0590	tRNA wobble adenosine to inosine editing
SGLAU_RS26265	COG2197	response regulator
SGLAU_RS26270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SGLAU_RS26275	COG0318	PFAM AMP-dependent synthetase and ligase
SGLAU_RS26300	COG5297	Belongs to the glycosyl hydrolase family 6
SGLAU_RS26315	COG3960	tartronate-semialdehyde synthase activity
SGLAU_RS26330	COG0753	catalase activity
SGLAU_RS26335	COG2084	Dehydrogenase
SGLAU_RS26340	COG3622	Belongs to the hyi family
SGLAU_RS26365	COG2351	hydroxyisourate hydrolase activity
SGLAU_RS26375	COG2233	PERMEase
SGLAU_RS26385	COG2233	PERMEase
SGLAU_RS26405	COG0406	alpha-ribazole phosphatase activity
SGLAU_RS26415	COG1733	regulation of RNA biosynthetic process
SGLAU_RS26455	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SGLAU_RS26465	COG1414	Transcriptional regulator
SGLAU_RS26470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGLAU_RS26475	COG4266	Belongs to the allantoicase family
SGLAU_RS26480	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS26510	COG2197	response regulator
SGLAU_RS26520	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS26525	COG2188	Transcriptional regulator
SGLAU_RS26545	COG1940	carbohydrate kinase activity
SGLAU_RS26555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SGLAU_RS26580	COG3693	PFAM glycoside hydrolase, family 10
SGLAU_RS26590	COG3345	alpha-galactosidase
SGLAU_RS26610	COG0513	Belongs to the DEAD box helicase family
SGLAU_RS26615	COG1278	Cold shock
SGLAU_RS26620	COG0513	Belongs to the DEAD box helicase family
SGLAU_RS26635	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SGLAU_RS26655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGLAU_RS26660	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SGLAU_RS26690	COG0405	Gamma-glutamyltransferase
SGLAU_RS26700	COG0714	Associated with various cellular activities
SGLAU_RS26710	COG0542	response to heat
SGLAU_RS26735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGLAU_RS26740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGLAU_RS26760	COG0483	inositol monophosphate 1-phosphatase activity
SGLAU_RS26770	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SGLAU_RS26825	COG0640	Transcriptional regulator
SGLAU_RS26840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGLAU_RS26845	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SGLAU_RS26865	COG1929	Belongs to the glycerate kinase type-1 family
SGLAU_RS26875	COG0688	phosphatidylethanolamine metabolic process
SGLAU_RS26880	COG1960	acyl-CoA dehydrogenase activity
SGLAU_RS26890	COG2301	Belongs to the HpcH HpaI aldolase family
SGLAU_RS26895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGLAU_RS26895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGLAU_RS26900	COG0604	alcohol dehydrogenase
SGLAU_RS26910	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGLAU_RS26925	COG0596	Alpha beta hydrolase
SGLAU_RS26950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGLAU_RS26960	COG1619	proteins homologs of microcin C7 resistance protein MccF
SGLAU_RS26990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS27000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SGLAU_RS27065	COG1597	lipid kinase activity
SGLAU_RS27070	COG0488	(ABC) transporter
SGLAU_RS27085	COG0693	protein deglycase activity
SGLAU_RS27090	COG0517	IMP dehydrogenase activity
SGLAU_RS27090	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SGLAU_RS27105	COG1309	transcriptional regulator
SGLAU_RS27120	COG0028	Belongs to the TPP enzyme family
SGLAU_RS27160	COG0531	amino acid
SGLAU_RS27200	COG2154	pterin-4-alpha-carbinolamine dehydratase
SGLAU_RS27205	COG2226	methyltransferase
SGLAU_RS27215	COG5297	Belongs to the glycosyl hydrolase family 6
SGLAU_RS27215	COG4733	cellulase activity
SGLAU_RS27220	COG5297	Belongs to the glycosyl hydrolase family 6
SGLAU_RS27230	COG0656	L-ascorbic acid biosynthetic process
SGLAU_RS27250	COG0483	inositol monophosphate 1-phosphatase activity
SGLAU_RS27270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SGLAU_RS27275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGLAU_RS27280	COG0702	epimerase
SGLAU_RS27285	COG1940	carbohydrate kinase activity
SGLAU_RS27290	COG1129	ABC transporter
SGLAU_RS27295	COG1172	Belongs to the binding-protein-dependent transport system permease family
SGLAU_RS27305	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS27415	COG3540	Alkaline phosphatase
SGLAU_RS27425	COG0601	transmembrane transport
SGLAU_RS27430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGLAU_RS27435	COG0444	Belongs to the ABC transporter superfamily
SGLAU_RS27445	COG1132	(ABC) transporter
SGLAU_RS27455	COG1122	ATPase activity
SGLAU_RS27460	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SGLAU_RS27465	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
SGLAU_RS27470	COG0310	cobalt ion transport
SGLAU_RS27475	COG0584	glycerophosphoryl diester phosphodiesterase
SGLAU_RS27485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGLAU_RS27510	COG0297	glycogen (starch) synthase activity
SGLAU_RS27530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGLAU_RS27540	COG0477	Major facilitator Superfamily
SGLAU_RS27550	COG2814	Major facilitator Superfamily
SGLAU_RS27560	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SGLAU_RS27565	COG0166	Belongs to the GPI family
SGLAU_RS27580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SGLAU_RS27615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SGLAU_RS27640	COG3511	phospholipase C
SGLAU_RS27680	COG1793	dna ligase
SGLAU_RS27725	COG1834	amidinotransferase
SGLAU_RS27730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SGLAU_RS27735	COG0488	(ABC) transporter
SGLAU_RS27740	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SGLAU_RS27760	COG1515	deoxyribonuclease V activity
SGLAU_RS27765	COG3268	Saccharopine dehydrogenase
SGLAU_RS27775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SGLAU_RS27780	COG0183	Belongs to the thiolase family
SGLAU_RS27785	COG1024	Enoyl-CoA hydratase
SGLAU_RS27785	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGLAU_RS27790	COG0789	Transcriptional regulator
SGLAU_RS27795	COG1113	amino acid transport
SGLAU_RS27805	COG2936	dipeptidyl-peptidase activity
SGLAU_RS27815	COG0488	(ABC) transporter
SGLAU_RS27820	COG2183	response to ionizing radiation
SGLAU_RS27845	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SGLAU_RS27890	COG1134	teichoic acid transport
SGLAU_RS27895	COG1562	ergosterol biosynthetic process
SGLAU_RS27910	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SGLAU_RS27920	COG1657	PFAM Prenyltransferase squalene oxidase
SGLAU_RS27935	COG5322	oxidoreductase activity
SGLAU_RS27935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGLAU_RS27950	COG2365	Tyrosine phosphatase family
SGLAU_RS27965	COG2755	lipolytic protein G-D-S-L family
SGLAU_RS27990	COG3629	intracellular signal transduction
SGLAU_RS27990	COG3903	Transcriptional regulator
SGLAU_RS28000	COG0477	Major facilitator Superfamily
SGLAU_RS28010	COG1175	transmembrane transport
SGLAU_RS28025	COG1609	Transcriptional regulator
SGLAU_RS28060	COG1063	alcohol dehydrogenase
SGLAU_RS28065	COG0156	8-amino-7-oxononanoate synthase activity
SGLAU_RS28070	COG0583	DNA-binding transcription factor activity
SGLAU_RS28130	COG0561	phosphatase activity
SGLAU_RS28135	COG2837	iron assimilation
SGLAU_RS28140	COG0515	serine threonine protein kinase
SGLAU_RS28140	COG2815	serine threonine protein kinase
SGLAU_RS28165	COG2267	carboxylic ester hydrolase activity
SGLAU_RS28170	COG0183	Belongs to the thiolase family
SGLAU_RS28195	COG2205	protein histidine kinase activity
SGLAU_RS28200	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS28215	COG1376	ErfK ybiS ycfS ynhG family protein
SGLAU_RS28295	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS28305	COG3548	integral membrane protein
SGLAU_RS28310	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS28345	COG2197	response regulator
SGLAU_RS28355	COG1404	Belongs to the peptidase S8 family
SGLAU_RS28375	COG2838	Isocitrate dehydrogenase
SGLAU_RS28385	COG0668	transmembrane transport
SGLAU_RS28400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SGLAU_RS28415	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS28420	COG1132	(ABC) transporter
SGLAU_RS28460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGLAU_RS28475	COG2159	amidohydrolase
SGLAU_RS28485	COG2124	cytochrome p450
SGLAU_RS28490	COG2329	Antibiotic biosynthesis monooxygenase
SGLAU_RS28495	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SGLAU_RS28510	COG2207	Transcriptional regulator
SGLAU_RS28515	COG1695	Transcriptional regulator
SGLAU_RS28525	COG2409	Drug exporters of the RND superfamily
SGLAU_RS28540	COG2197	response regulator
SGLAU_RS28545	COG2345	Transcriptional regulator
SGLAU_RS28555	COG0300	oxidoreductase activity
SGLAU_RS28570	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS28595	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS28600	COG2867	negative regulation of translational initiation
SGLAU_RS28605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGLAU_RS28610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGLAU_RS28615	COG0662	Cupin 2, conserved barrel domain protein
SGLAU_RS28625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGLAU_RS28640	COG2132	Multicopper oxidase
SGLAU_RS28695	COG1408	metallophosphoesterase
SGLAU_RS28700	COG1404	Belongs to the peptidase S8 family
SGLAU_RS28710	COG1522	sequence-specific DNA binding
SGLAU_RS28725	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
SGLAU_RS28730	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SGLAU_RS28745	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SGLAU_RS28765	COG0297	glycogen (starch) synthase activity
SGLAU_RS28770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGLAU_RS28805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGLAU_RS28810	COG2208	phosphoserine phosphatase activity
SGLAU_RS28810	COG2770	Histidine kinase
SGLAU_RS28840	COG2267	carboxylic ester hydrolase activity
SGLAU_RS28845	COG0531	amino acid
SGLAU_RS28855	COG0726	polysaccharide deacetylase
SGLAU_RS28905	COG0583	DNA-binding transcription factor activity
SGLAU_RS28915	COG1053	succinate dehydrogenase
SGLAU_RS28920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SGLAU_RS28940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS28950	COG3360	Dodecin
SGLAU_RS28955	COG2182	Extracellular solute-binding protein
SGLAU_RS28960	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SGLAU_RS28965	COG0121	glutamine amidotransferase
SGLAU_RS28970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SGLAU_RS28975	COG3572	ergothioneine biosynthetic process
SGLAU_RS28995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SGLAU_RS29010	COG1609	Transcriptional regulator
SGLAU_RS29015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SGLAU_RS29020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGLAU_RS29025	COG0242	peptide deformylase activity
SGLAU_RS29055	COG2208	phosphoserine phosphatase activity
SGLAU_RS29065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SGLAU_RS29090	COG1127	ABC transporter
SGLAU_RS29100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SGLAU_RS29125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SGLAU_RS29185	COG0431	NADPH-dependent FMN reductase
SGLAU_RS29195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGLAU_RS29200	COG4733	cellulase activity
SGLAU_RS29200	COG5297	Belongs to the glycosyl hydrolase family 6
SGLAU_RS29260	COG1191	sigma factor activity
SGLAU_RS29300	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS29305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SGLAU_RS29320	COG0477	Major facilitator Superfamily
SGLAU_RS29340	COG2964	Protein conserved in bacteria
SGLAU_RS29360	COG0542	response to heat
SGLAU_RS29365	COG1556	Lactate utilization protein
SGLAU_RS29370	COG1139	Iron-sulfur cluster binding protein
SGLAU_RS29375	COG0247	lactate metabolic process
SGLAU_RS29380	COG1070	Carbohydrate kinase
SGLAU_RS29385	COG3347	Dehydrogenase
SGLAU_RS29385	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS29390	COG4952	isomerase
SGLAU_RS29400	COG1609	Transcriptional regulator
SGLAU_RS29415	COG1357	PFAM Pentapeptide repeats (8 copies)
SGLAU_RS29425	COG2706	6-phosphogluconolactonase activity
SGLAU_RS29460	COG1796	DNA polymerase
SGLAU_RS29460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SGLAU_RS29465	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS29530	COG2124	cytochrome p450
SGLAU_RS29545	COG0435	Glutathione S-transferase
SGLAU_RS29570	COG0667	Aldo Keto reductase
SGLAU_RS29585	COG5002	protein histidine kinase activity
SGLAU_RS29585	COG2205	protein histidine kinase activity
SGLAU_RS29585	COG0784	Response regulator, receiver
SGLAU_RS29630	COG2890	protein-(glutamine-N5) methyltransferase activity
SGLAU_RS29645	COG0248	Ppx GppA phosphatase
SGLAU_RS29650	COG2274	protein secretion by the type I secretion system
SGLAU_RS29690	COG0517	IMP dehydrogenase activity
SGLAU_RS29725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SGLAU_RS29735	COG1132	(ABC) transporter
SGLAU_RS29750	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS29795	COG1309	transcriptional regulator
SGLAU_RS29855	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SGLAU_RS29870	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS29890	COG0410	ABC transporter
SGLAU_RS29900	COG0559	Belongs to the binding-protein-dependent transport system permease family
SGLAU_RS29940	COG1132	(ABC) transporter
SGLAU_RS29975	COG0640	Transcriptional regulator
SGLAU_RS29990	COG1073	alpha beta
SGLAU_RS29990	COG2226	methyltransferase
SGLAU_RS30015	COG1959	2 iron, 2 sulfur cluster binding
SGLAU_RS30015	COG1295	ribonuclease BN
SGLAU_RS30050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SGLAU_RS30050	COG1017	nitric oxide dioxygenase activity
SGLAU_RS30065	COG1864	DNA RNA non-specific endonuclease
SGLAU_RS30065	COG3591	Belongs to the peptidase S1B family
SGLAU_RS30100	COG2182	Extracellular solute-binding protein
SGLAU_RS30105	COG1175	transmembrane transport
SGLAU_RS30110	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS30115	COG2723	6-phospho-beta-galactosidase activity
SGLAU_RS30120	COG1609	Transcriptional regulator
SGLAU_RS30165	COG2272	Belongs to the type-B carboxylesterase lipase family
SGLAU_RS30220	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS30240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGLAU_RS30265	COG3507	Belongs to the glycosyl hydrolase 43 family
SGLAU_RS30300	COG1278	Cold shock
SGLAU_RS30305	COG0789	Transcriptional regulator
SGLAU_RS30335	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS30340	COG4251	negative regulation of phosphorylation
SGLAU_RS30345	COG0784	Response regulator, receiver
SGLAU_RS30360	COG2207	Transcriptional regulator
SGLAU_RS30360	COG3708	Transcriptional regulator
SGLAU_RS30375	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS30395	COG0514	ATP-dependent DNA helicase (RecQ)
SGLAU_RS30420	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS30440	COG1231	oxidoreductase activity
SGLAU_RS30445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGLAU_RS30465	COG2340	Cysteine-rich secretory protein family
SGLAU_RS30520	COG0596	Alpha beta hydrolase
SGLAU_RS30535	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS30575	COG3851	Histidine kinase
SGLAU_RS30580	COG2197	response regulator
SGLAU_RS30590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGLAU_RS30590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGLAU_RS30615	COG0302	gtp cyclohydrolase
SGLAU_RS30645	COG1132	(ABC) transporter
SGLAU_RS30655	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS30660	COG1175	transmembrane transport
SGLAU_RS30665	COG1653	transport
SGLAU_RS30670	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGLAU_RS30675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGLAU_RS30695	COG1482	cell wall glycoprotein biosynthetic process
SGLAU_RS30720	COG1113	amino acid transport
SGLAU_RS30725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SGLAU_RS30765	COG1295	ribonuclease BN
SGLAU_RS30785	COG2084	Dehydrogenase
SGLAU_RS30800	COG2124	cytochrome p450
SGLAU_RS30820	COG3251	PFAM MbtH domain protein
SGLAU_RS30840	COG1278	Cold shock
SGLAU_RS30845	COG0513	Belongs to the DEAD box helicase family
SGLAU_RS30855	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS30860	COG1175	transmembrane transport
SGLAU_RS30875	COG3250	beta-galactosidase activity
SGLAU_RS30890	COG0596	Alpha beta hydrolase
SGLAU_RS30895	COG0673	inositol 2-dehydrogenase activity
SGLAU_RS30905	COG0667	Aldo Keto reductase
SGLAU_RS30910	COG0789	Transcriptional regulator
SGLAU_RS30930	COG0789	Transcriptional regulator
SGLAU_RS31020	COG1280	lysine exporter protein (LysE YggA)
SGLAU_RS31025	COG2199	diguanylate cyclase activity
SGLAU_RS31025	COG2200	EAL domain
SGLAU_RS31025	COG2202	Pas domain
SGLAU_RS31030	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
SGLAU_RS31040	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS31045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGLAU_RS31070	COG2409	Drug exporters of the RND superfamily
SGLAU_RS31080	COG0745	RESPONSE REGULATOR receiver
SGLAU_RS31145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SGLAU_RS31165	COG2272	Belongs to the type-B carboxylesterase lipase family
SGLAU_RS31230	COG4552	Acetyltransferase involved in intracellular survival and related
SGLAU_RS31240	COG1309	transcriptional regulator
SGLAU_RS31245	COG0300	oxidoreductase activity
SGLAU_RS31260	COG2045	Belongs to the ComB family
SGLAU_RS31275	COG4585	Histidine kinase
SGLAU_RS31285	COG2755	lipolytic protein G-D-S-L family
SGLAU_RS31300	COG2226	methyltransferase
SGLAU_RS31305	COG4221	oxidoreductase activity
SGLAU_RS31310	COG2308	Evidence 4 Homologs of previously reported genes of
SGLAU_RS31310	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SGLAU_RS31320	COG2135	peptidase activity
SGLAU_RS31360	COG4106	trans-aconitate 2-methyltransferase activity
SGLAU_RS31370	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS31400	COG1846	Transcriptional regulator
SGLAU_RS31400	COG1940	carbohydrate kinase activity
SGLAU_RS31405	COG0366	Alpha amylase catalytic
SGLAU_RS31420	COG0395	ABC-type sugar transport system, permease component
SGLAU_RS31470	COG3209	COG3209 Rhs family protein
SGLAU_RS31490	COG0477	Major facilitator Superfamily
SGLAU_RS31495	COG1733	regulation of RNA biosynthetic process
SGLAU_RS31550	COG1472	Belongs to the glycosyl hydrolase 3 family
SGLAU_RS31585	COG2226	methyltransferase
SGLAU_RS31605	COG2197	response regulator
SGLAU_RS31620	COG1136	(ABC) transporter
SGLAU_RS31625	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGLAU_RS31635	COG4221	oxidoreductase activity
SGLAU_RS31645	COG1309	transcriptional regulator
SGLAU_RS31650	COG0655	NAD(P)H dehydrogenase (quinone) activity
SGLAU_RS31655	COG2070	2-Nitropropane dioxygenase
SGLAU_RS31660	COG0831	urea catabolic process
SGLAU_RS31665	COG0804	urea catabolic process
SGLAU_RS31670	COG0830	nickel cation binding
SGLAU_RS31675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SGLAU_RS31680	COG0829	nickel cation binding
SGLAU_RS31720	COG0463	Glycosyl transferase, family 2
SGLAU_RS31735	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGLAU_RS31745	COG2226	methyltransferase
SGLAU_RS31760	COG0583	DNA-binding transcription factor activity
SGLAU_RS31800	COG1028	Short-chain dehydrogenase reductase Sdr
SGLAU_RS31805	COG1959	2 iron, 2 sulfur cluster binding
SGLAU_RS31900	COG2378	regulation of single-species biofilm formation
SGLAU_RS32740	COG5297	Belongs to the glycosyl hydrolase family 6
SGLAU_RS32740	COG4733	cellulase activity
SGLAU_RS32780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGLAU_RS32815	COG0604	alcohol dehydrogenase
SGLAU_RS32815	COG3321	synthase
SGLAU_RS32835	COG2318	DinB family
SGLAU_RS32880	COG1404	Belongs to the peptidase S8 family
SGLAU_RS32935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SGLAU_RS33035	COG2205	protein histidine kinase activity