locus-tag	class	description
DIJ69_RS00050	COG2801	Transposase and inactivated derivatives
DIJ69_RS00075	COG0596	Alpha beta hydrolase
DIJ69_RS00120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DIJ69_RS00155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIJ69_RS00160	COG0028	Belongs to the TPP enzyme family
DIJ69_RS00205	COG1070	Carbohydrate kinase
DIJ69_RS00220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIJ69_RS00230	COG4213	ABC transporter substrate-binding protein
DIJ69_RS00240	COG4214	carbohydrate transport
DIJ69_RS00255	COG1595	DNA-templated transcription, initiation
DIJ69_RS00275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DIJ69_RS00280	COG1175	transmembrane transport
DIJ69_RS00285	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS00290	COG1609	Transcriptional regulator
DIJ69_RS00295	COG1874	Beta-galactosidase
DIJ69_RS00310	COG2226	methyltransferase
DIJ69_RS00315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DIJ69_RS00325	COG0586	Pfam SNARE associated Golgi protein
DIJ69_RS00370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DIJ69_RS00385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DIJ69_RS00390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS00430	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DIJ69_RS00435	COG0714	Associated with various cellular activities
DIJ69_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS00450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DIJ69_RS00460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DIJ69_RS00465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DIJ69_RS00470	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS00500	COG2318	DinB family
DIJ69_RS00550	COG0009	L-threonylcarbamoyladenylate synthase
DIJ69_RS00570	COG0488	(ABC) transporter
DIJ69_RS00590	COG0583	DNA-binding transcription factor activity
DIJ69_RS00625	COG2340	Cysteine-rich secretory protein family
DIJ69_RS00640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DIJ69_RS00645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIJ69_RS00665	COG1024	Enoyl-CoA hydratase
DIJ69_RS00695	COG2018	Roadblock/LC7 domain
DIJ69_RS00710	COG0640	Transcriptional regulator
DIJ69_RS00715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DIJ69_RS00720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIJ69_RS00750	COG3239	Fatty acid desaturase
DIJ69_RS00755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DIJ69_RS00775	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS00800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIJ69_RS00835	COG0326	Molecular chaperone. Has ATPase activity
DIJ69_RS00860	COG1794	racemase activity, acting on amino acids and derivatives
DIJ69_RS00885	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DIJ69_RS00885	COG1672	PFAM Archaeal ATPase
DIJ69_RS00900	COG1408	metallophosphoesterase
DIJ69_RS00910	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS00915	COG0789	Transcriptional regulator
DIJ69_RS00950	COG1063	alcohol dehydrogenase
DIJ69_RS00970	COG4044	May play a role in the intracellular transport of hydrophobic ligands
DIJ69_RS00980	COG2375	cellular response to nickel ion
DIJ69_RS00990	COG0693	protein deglycase activity
DIJ69_RS00995	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DIJ69_RS01010	COG1278	Cold shock
DIJ69_RS01075	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DIJ69_RS01115	COG1796	DNA polymerase
DIJ69_RS01115	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DIJ69_RS01200	COG0444	Belongs to the ABC transporter superfamily
DIJ69_RS01205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIJ69_RS01210	COG0601	transmembrane transport
DIJ69_RS01220	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS01225	COG1175	transmembrane transport
DIJ69_RS01240	COG2188	Transcriptional regulator
DIJ69_RS01245	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS01250	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS01270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DIJ69_RS01280	COG0656	L-ascorbic acid biosynthetic process
DIJ69_RS01320	COG0438	transferase activity, transferring glycosyl groups
DIJ69_RS01340	COG0726	polysaccharide deacetylase
DIJ69_RS01345	COG0438	transferase activity, transferring glycosyl groups
DIJ69_RS01365	COG2304	oxidoreductase activity
DIJ69_RS01390	COG1132	(ABC) transporter
DIJ69_RS01425	COG1120	ATPase activity
DIJ69_RS01430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS01450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DIJ69_RS01455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DIJ69_RS01460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DIJ69_RS01465	COG0254	rRNA binding
DIJ69_RS01475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DIJ69_RS01480	COG0477	Major facilitator Superfamily
DIJ69_RS01490	COG1120	ATPase activity
DIJ69_RS01505	COG3250	beta-galactosidase activity
DIJ69_RS01510	COG1070	Carbohydrate kinase
DIJ69_RS01520	COG4952	isomerase
DIJ69_RS01525	COG1129	ABC transporter
DIJ69_RS01530	COG1172	Belongs to the binding-protein-dependent transport system permease family
DIJ69_RS01545	COG1609	Transcriptional regulator
DIJ69_RS01575	COG1233	COG1233 Phytoene dehydrogenase and related
DIJ69_RS01600	COG0657	acetylesterase activity
DIJ69_RS01615	COG1024	Enoyl-CoA hydratase
DIJ69_RS01620	COG1131	(ABC) transporter
DIJ69_RS01630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIJ69_RS01640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIJ69_RS01645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIJ69_RS01650	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS01685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIJ69_RS01690	COG1024	Enoyl-CoA hydratase
DIJ69_RS01715	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DIJ69_RS01730	COG0640	Transcriptional regulator
DIJ69_RS01735	COG0587	DNA-directed DNA polymerase activity
DIJ69_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS01795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DIJ69_RS01820	COG1228	amidohydrolase
DIJ69_RS01830	COG1834	amidinotransferase
DIJ69_RS01845	COG3903	Transcriptional regulator
DIJ69_RS01845	COG3629	intracellular signal transduction
DIJ69_RS01850	COG2045	Belongs to the ComB family
DIJ69_RS01860	COG1357	PFAM Pentapeptide repeats (8 copies)
DIJ69_RS01885	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DIJ69_RS01890	COG0714	Associated with various cellular activities
DIJ69_RS01915	COG0477	Major facilitator Superfamily
DIJ69_RS01920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DIJ69_RS01925	COG0297	glycogen (starch) synthase activity
DIJ69_RS01935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIJ69_RS01940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIJ69_RS01950	COG1609	Transcriptional regulator
DIJ69_RS01970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIJ69_RS01975	COG0121	glutamine amidotransferase
DIJ69_RS01980	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DIJ69_RS01995	COG2182	Extracellular solute-binding protein
DIJ69_RS02000	COG3360	Dodecin
DIJ69_RS02020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DIJ69_RS02025	COG1053	succinate dehydrogenase
DIJ69_RS02035	COG0583	DNA-binding transcription factor activity
DIJ69_RS02110	COG3275	phosphorelay sensor kinase activity
DIJ69_RS02115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIJ69_RS02135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DIJ69_RS02175	COG1191	sigma factor activity
DIJ69_RS02185	COG4251	negative regulation of phosphorylation
DIJ69_RS02190	COG0784	Response regulator, receiver
DIJ69_RS02250	COG1940	carbohydrate kinase activity
DIJ69_RS02265	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS02275	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DIJ69_RS02310	COG1119	ATPase activity
DIJ69_RS02330	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DIJ69_RS02335	COG2837	iron assimilation
DIJ69_RS02345	COG0019	diaminopimelate decarboxylase activity
DIJ69_RS02355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIJ69_RS02365	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DIJ69_RS02415	COG2188	Transcriptional regulator
DIJ69_RS02425	COG1175	transmembrane transport
DIJ69_RS02430	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS02435	COG4948	Mandelate Racemase Muconate Lactonizing
DIJ69_RS02445	COG2130	NADP-dependent
DIJ69_RS02450	COG1233	COG1233 Phytoene dehydrogenase and related
DIJ69_RS02495	COG1846	Transcriptional regulator
DIJ69_RS02500	COG2409	Drug exporters of the RND superfamily
DIJ69_RS02515	COG0446	pyridine nucleotide-disulphide oxidoreductase
DIJ69_RS02515	COG1902	pentaerythritol trinitrate reductase activity
DIJ69_RS02550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DIJ69_RS02565	COG1953	Uracil, thiamine, allantoin
DIJ69_RS02575	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DIJ69_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS02615	COG1556	Lactate utilization protein
DIJ69_RS02620	COG1139	Iron-sulfur cluster binding protein
DIJ69_RS02625	COG0247	lactate metabolic process
DIJ69_RS02630	COG2186	Transcriptional regulator
DIJ69_RS02640	COG3851	Histidine kinase
DIJ69_RS02645	COG2197	response regulator
DIJ69_RS02655	COG3511	phospholipase C
DIJ69_RS02685	COG3959	Transketolase, thiamine diphosphate binding domain
DIJ69_RS02690	COG3958	Transketolase
DIJ69_RS02700	COG3507	Belongs to the glycosyl hydrolase 43 family
DIJ69_RS02715	COG1116	anion transmembrane transporter activity
DIJ69_RS02725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIJ69_RS02730	COG1609	Transcriptional regulator
DIJ69_RS02785	COG0789	Transcriptional regulator
DIJ69_RS02795	COG3467	pyridoxamine 5'-phosphate
DIJ69_RS02880	COG1657	PFAM Prenyltransferase squalene oxidase
DIJ69_RS02890	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DIJ69_RS02900	COG1562	ergosterol biosynthetic process
DIJ69_RS02905	COG1134	teichoic acid transport
DIJ69_RS02905	COG1388	LysM domain
DIJ69_RS02925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DIJ69_RS02970	COG1024	Enoyl-CoA hydratase
DIJ69_RS02980	COG4977	sequence-specific DNA binding
DIJ69_RS03000	COG0488	(ABC) transporter
DIJ69_RS03020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DIJ69_RS03050	COG0789	Transcriptional regulator
DIJ69_RS03055	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIJ69_RS03055	COG1024	Enoyl-CoA hydratase
DIJ69_RS03060	COG0183	Belongs to the thiolase family
DIJ69_RS03065	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS03070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DIJ69_RS03075	COG3268	Saccharopine dehydrogenase
DIJ69_RS03085	COG1515	deoxyribonuclease V activity
DIJ69_RS03115	COG0488	(ABC) transporter
DIJ69_RS03120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DIJ69_RS03175	COG1793	dna ligase
DIJ69_RS03180	COG2326	polyphosphate kinase activity
DIJ69_RS03220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DIJ69_RS03245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DIJ69_RS03290	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS03315	COG3012	SEC-C Motif Domain Protein
DIJ69_RS03345	COG1486	melibiose metabolic process
DIJ69_RS03350	COG2124	cytochrome p450
DIJ69_RS03375	COG1846	Transcriptional regulator
DIJ69_RS03400	COG1940	carbohydrate kinase activity
DIJ69_RS03430	COG0569	domain protein
DIJ69_RS03430	COG2985	domain, Protein
DIJ69_RS03455	COG4176	ABC-type proline glycine betaine transport system permease component
DIJ69_RS03460	COG4175	Glycine betaine
DIJ69_RS03460	COG0517	IMP dehydrogenase activity
DIJ69_RS03470	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS03500	COG2255	four-way junction helicase activity
DIJ69_RS03525	COG5002	protein histidine kinase activity
DIJ69_RS03540	COG3568	Endonuclease Exonuclease Phosphatase
DIJ69_RS03550	COG3903	Transcriptional regulator
DIJ69_RS03550	COG3629	intracellular signal transduction
DIJ69_RS03565	COG0714	Associated with various cellular activities
DIJ69_RS03575	COG1376	ErfK ybiS ycfS ynhG family protein
DIJ69_RS03590	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS03595	COG2205	protein histidine kinase activity
DIJ69_RS03605	COG1869	D-ribose catabolic process
DIJ69_RS03610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIJ69_RS03620	COG1129	ABC transporter
DIJ69_RS03675	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DIJ69_RS03695	COG0673	inositol 2-dehydrogenase activity
DIJ69_RS03700	COG1879	ABC-type sugar transport system periplasmic component
DIJ69_RS03705	COG1172	Belongs to the binding-protein-dependent transport system permease family
DIJ69_RS03710	COG1129	ABC transporter
DIJ69_RS03720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIJ69_RS03725	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DIJ69_RS03750	COG0656	L-ascorbic acid biosynthetic process
DIJ69_RS03760	COG4106	trans-aconitate 2-methyltransferase activity
DIJ69_RS03770	COG0702	epimerase
DIJ69_RS03780	COG2154	pterin-4-alpha-carbinolamine dehydratase
DIJ69_RS03790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DIJ69_RS03790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DIJ69_RS03805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DIJ69_RS03860	COG0457	Tetratricopeptide repeat
DIJ69_RS03880	COG1619	proteins homologs of microcin C7 resistance protein MccF
DIJ69_RS03890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DIJ69_RS03895	COG2362	D-Aminopeptidase
DIJ69_RS03915	COG0667	Aldo Keto reductase
DIJ69_RS03920	COG0583	DNA-binding transcription factor activity
DIJ69_RS03945	COG0596	Alpha beta hydrolase
DIJ69_RS03960	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIJ69_RS03975	COG0604	alcohol dehydrogenase
DIJ69_RS03980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DIJ69_RS03980	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DIJ69_RS03985	COG2301	Belongs to the HpcH HpaI aldolase family
DIJ69_RS03995	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS04000	COG0688	phosphatidylethanolamine metabolic process
DIJ69_RS04030	COG0559	Belongs to the binding-protein-dependent transport system permease family
DIJ69_RS04050	COG1929	Belongs to the glycerate kinase type-1 family
DIJ69_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS04110	COG2072	flavoprotein involved in K transport
DIJ69_RS04145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DIJ69_RS04165	COG0483	inositol monophosphate 1-phosphatase activity
DIJ69_RS04195	COG2233	PERMEase
DIJ69_RS04225	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DIJ69_RS04245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DIJ69_RS04265	COG0095	Lipoate-protein ligase
DIJ69_RS04285	COG2838	Isocitrate dehydrogenase
DIJ69_RS04290	COG2205	protein histidine kinase activity
DIJ69_RS04300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIJ69_RS04310	COG1191	sigma factor activity
DIJ69_RS04330	COG1953	Uracil, thiamine, allantoin
DIJ69_RS04340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DIJ69_RS04345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIJ69_RS04380	COG0405	Gamma-glutamyltransferase
DIJ69_RS04405	COG0765	amino acid transport
DIJ69_RS04410	COG0765	amino acid transport
DIJ69_RS04415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIJ69_RS04420	COG1126	abc transporter atp-binding protein
DIJ69_RS04430	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS04445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DIJ69_RS04450	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIJ69_RS04460	COG1940	carbohydrate kinase activity
DIJ69_RS04465	COG1129	ABC transporter
DIJ69_RS04475	COG1879	ABC-type sugar transport system periplasmic component
DIJ69_RS04480	COG2188	Transcriptional regulator
DIJ69_RS04485	COG0673	inositol 2-dehydrogenase activity
DIJ69_RS04500	COG2197	response regulator
DIJ69_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS04530	COG0656	L-ascorbic acid biosynthetic process
DIJ69_RS04535	COG4266	Belongs to the allantoicase family
DIJ69_RS04540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DIJ69_RS04545	COG1414	Transcriptional regulator
DIJ69_RS04550	COG1136	(ABC) transporter
DIJ69_RS04575	COG0746	molybdenum cofactor guanylyltransferase activity
DIJ69_RS04580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DIJ69_RS04605	COG2233	PERMEase
DIJ69_RS04615	COG2233	PERMEase
DIJ69_RS04625	COG2351	hydroxyisourate hydrolase activity
DIJ69_RS04645	COG2706	6-phosphogluconolactonase activity
DIJ69_RS04650	COG2188	Transcriptional regulator
DIJ69_RS04660	COG1175	transmembrane transport
DIJ69_RS04665	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS04670	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIJ69_RS04675	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DIJ69_RS04680	COG3622	Belongs to the hyi family
DIJ69_RS04685	COG2084	Dehydrogenase
DIJ69_RS04690	COG0753	catalase activity
DIJ69_RS04705	COG3960	tartronate-semialdehyde synthase activity
DIJ69_RS04725	COG0318	PFAM AMP-dependent synthetase and ligase
DIJ69_RS04730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIJ69_RS04735	COG2197	response regulator
DIJ69_RS04750	COG0435	Glutathione S-transferase
DIJ69_RS04780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIJ69_RS04800	COG1309	transcriptional regulator
DIJ69_RS04825	COG1404	Belongs to the peptidase S8 family
DIJ69_RS04830	COG3608	succinylglutamate desuccinylase aspartoacylase
DIJ69_RS04830	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DIJ69_RS04835	COG2252	PERMEase
DIJ69_RS04840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DIJ69_RS04865	COG1802	Transcriptional regulator
DIJ69_RS04895	COG0028	Belongs to the TPP enzyme family
DIJ69_RS04925	COG1162	GTPase activity
DIJ69_RS04975	COG0183	Belongs to the thiolase family
DIJ69_RS04980	COG0583	DNA-binding transcription factor activity
DIJ69_RS04985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DIJ69_RS04990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DIJ69_RS04995	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIJ69_RS05015	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS05030	COG1191	sigma factor activity
DIJ69_RS05055	COG0175	sulfate reduction
DIJ69_RS05060	COG0529	Catalyzes the synthesis of activated sulfate
DIJ69_RS05080	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DIJ69_RS05085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIJ69_RS05095	COG2226	methyltransferase
DIJ69_RS05110	COG1120	ATPase activity
DIJ69_RS05115	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS05120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS05125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DIJ69_RS05130	COG1132	(ABC) transporter
DIJ69_RS05155	COG1404	Belongs to the peptidase S8 family
DIJ69_RS05175	COG1175	transmembrane transport
DIJ69_RS05270	COG0346	lactoylglutathione lyase activity
DIJ69_RS05290	COG0583	DNA-binding transcription factor activity
DIJ69_RS05295	COG0156	8-amino-7-oxononanoate synthase activity
DIJ69_RS05300	COG1063	alcohol dehydrogenase
DIJ69_RS05305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DIJ69_RS05305	COG0515	serine threonine protein kinase
DIJ69_RS05325	COG2267	carboxylic ester hydrolase activity
DIJ69_RS05410	COG1653	transport
DIJ69_RS05445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIJ69_RS05450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DIJ69_RS05505	COG3220	belongs to the UPF0276 family
DIJ69_RS05520	COG3253	May function as heme-dependent peroxidase
DIJ69_RS05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DIJ69_RS05535	COG0446	pyridine nucleotide-disulphide oxidoreductase
DIJ69_RS05540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DIJ69_RS05560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DIJ69_RS05565	COG0183	Belongs to the thiolase family
DIJ69_RS05570	COG1024	Enoyl-CoA hydratase
DIJ69_RS05570	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIJ69_RS05575	COG1316	TRANSCRIPTIONal
DIJ69_RS05590	COG0531	amino acid
DIJ69_RS05595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DIJ69_RS05600	COG4214	carbohydrate transport
DIJ69_RS05610	COG4213	ABC transporter substrate-binding protein
DIJ69_RS05615	COG1940	carbohydrate kinase activity
DIJ69_RS05620	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS05625	COG1175	transmembrane transport
DIJ69_RS05630	COG1653	transport
DIJ69_RS05640	COG0588	phosphoglycerate mutase activity
DIJ69_RS05650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DIJ69_RS05665	COG1742	UPF0060 membrane protein
DIJ69_RS05690	COG3548	integral membrane protein
DIJ69_RS05695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIJ69_RS05700	COG0525	valine-tRNA ligase activity
DIJ69_RS05715	COG0500	methyltransferase
DIJ69_RS05760	COG3251	PFAM MbtH domain protein
DIJ69_RS05770	COG1131	(ABC) transporter
DIJ69_RS05810	COG2319	Wd-40 repeat
DIJ69_RS05815	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DIJ69_RS05850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIJ69_RS05875	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS05895	COG2172	sigma factor antagonist activity
DIJ69_RS05895	COG2208	phosphoserine phosphatase activity
DIJ69_RS05895	COG1366	Belongs to the anti-sigma-factor antagonist family
DIJ69_RS05910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DIJ69_RS05915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIJ69_RS05920	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DIJ69_RS05960	COG0489	protein tyrosine kinase activity
DIJ69_RS05965	COG0297	glycogen (starch) synthase activity
DIJ69_RS05985	COG1320	monovalent cation:proton antiporter activity
DIJ69_RS06000	COG0651	ATP synthesis coupled electron transport
DIJ69_RS06005	COG1006	Multisubunit Na H antiporter MnhC subunit
DIJ69_RS06010	COG2111	Na H antiporter
DIJ69_RS06010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIJ69_RS06055	COG1024	Enoyl-CoA hydratase
DIJ69_RS06065	COG0531	amino acid
DIJ69_RS06070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DIJ69_RS06080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DIJ69_RS06140	COG2040	homocysteine
DIJ69_RS06160	COG1799	cell septum assembly
DIJ69_RS06165	COG1349	DNA-binding transcription factor activity
DIJ69_RS06170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DIJ69_RS06175	COG0586	Pfam SNARE associated Golgi protein
DIJ69_RS06185	COG3467	pyridoxamine 5'-phosphate
DIJ69_RS06190	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS06195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS06220	COG3046	protein related to deoxyribodipyrimidine photolyase
DIJ69_RS06225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIJ69_RS06230	COG1280	lysine exporter protein (LysE YggA)
DIJ69_RS06240	COG3291	Pkd domain containing protein
DIJ69_RS06245	COG1802	Transcriptional regulator
DIJ69_RS06250	COG3938	Belongs to the proline racemase family
DIJ69_RS06260	COG0446	pyridine nucleotide-disulphide oxidoreductase
DIJ69_RS06270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIJ69_RS06280	COG0477	Major facilitator Superfamily
DIJ69_RS06315	COG2843	Capsule synthesis protein
DIJ69_RS06345	COG0803	Belongs to the bacterial solute-binding protein 9 family
DIJ69_RS06355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DIJ69_RS06360	COG1120	ATPase activity
DIJ69_RS06410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DIJ69_RS06415	COG0531	amino acid
DIJ69_RS06420	COG0569	domain protein
DIJ69_RS06450	COG1136	(ABC) transporter
DIJ69_RS06450	COG4591	ABC-type transport system involved in lipoprotein release permease component
DIJ69_RS06485	COG2205	protein histidine kinase activity
DIJ69_RS06490	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS06540	COG1435	thymidine kinase activity
DIJ69_RS06555	COG0045	succinate-CoA ligase (ADP-forming) activity
DIJ69_RS06555	COG1042	CoA-binding domain protein
DIJ69_RS06555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIJ69_RS06560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIJ69_RS06565	COG1802	Transcriptional regulator
DIJ69_RS06580	COG0612	Peptidase, M16
DIJ69_RS06585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIJ69_RS06595	COG0372	Belongs to the citrate synthase family
DIJ69_RS06600	COG0372	Belongs to the citrate synthase family
DIJ69_RS06610	COG3290	protein histidine kinase activity
DIJ69_RS06615	COG4565	transcriptional regulatory protein
DIJ69_RS06620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIJ69_RS06645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DIJ69_RS06650	COG1802	Transcriptional regulator
DIJ69_RS06685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIJ69_RS06725	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DIJ69_RS06730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DIJ69_RS06770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DIJ69_RS06780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DIJ69_RS06785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DIJ69_RS06795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DIJ69_RS06815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DIJ69_RS06825	COG2205	protein histidine kinase activity
DIJ69_RS06830	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS06835	COG1126	abc transporter atp-binding protein
DIJ69_RS06840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIJ69_RS06845	COG0765	amino acid transport
DIJ69_RS06850	COG0765	amino acid transport
DIJ69_RS06855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIJ69_RS06880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DIJ69_RS06920	COG2207	Transcriptional regulator
DIJ69_RS06920	COG1917	Cupin 2, conserved barrel domain protein
DIJ69_RS06925	COG1201	RNA secondary structure unwinding
DIJ69_RS06935	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS06950	COG0783	Belongs to the Dps family
DIJ69_RS06955	COG1396	sequence-specific DNA binding
DIJ69_RS06960	COG1058	Belongs to the CinA family
DIJ69_RS06960	COG1546	Belongs to the CinA family
DIJ69_RS06980	COG1674	ftsk spoiiie
DIJ69_RS06990	COG2205	protein histidine kinase activity
DIJ69_RS06990	COG4999	Histidine kinase
DIJ69_RS06990	COG3850	Histidine kinase
DIJ69_RS06990	COG3437	response regulator, receiver
DIJ69_RS06995	COG2208	phosphoserine phosphatase activity
DIJ69_RS06995	COG2770	Histidine kinase
DIJ69_RS07025	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DIJ69_RS07030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIJ69_RS07035	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DIJ69_RS07055	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DIJ69_RS07060	COG0612	Peptidase, M16
DIJ69_RS07065	COG1185	polyribonucleotide nucleotidyltransferase activity
DIJ69_RS07070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DIJ69_RS07080	COG1674	ftsk spoiiie
DIJ69_RS07085	COG4842	Belongs to the WXG100 family
DIJ69_RS07095	COG1404	Belongs to the peptidase S8 family
DIJ69_RS07110	COG1404	Belongs to the peptidase S8 family
DIJ69_RS07115	COG3266	domain, Protein
DIJ69_RS07135	COG0455	bacterial-type flagellum organization
DIJ69_RS07140	COG0747	negative chemotaxis
DIJ69_RS07145	COG0601	transmembrane transport
DIJ69_RS07150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIJ69_RS07160	COG4608	Belongs to the ABC transporter superfamily
DIJ69_RS07195	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DIJ69_RS07210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DIJ69_RS07225	COG0779	Required for maturation of 30S ribosomal subunits
DIJ69_RS07245	COG0442	prolyl-tRNA aminoacylation
DIJ69_RS07260	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DIJ69_RS07265	COG0750	zinc metalloprotease
DIJ69_RS07270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DIJ69_RS07275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DIJ69_RS07290	COG2508	Transcriptional regulator
DIJ69_RS07325	COG1177	transmembrane transport
DIJ69_RS07330	COG1176	ABC-type spermidine putrescine transport system, permease component I
DIJ69_RS07335	COG3842	ATPase activity
DIJ69_RS07340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DIJ69_RS07365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DIJ69_RS07380	COG4585	Histidine kinase
DIJ69_RS07385	COG2197	response regulator
DIJ69_RS07405	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS07415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DIJ69_RS07420	COG4181	ATPase activity
DIJ69_RS07435	COG0438	transferase activity, transferring glycosyl groups
DIJ69_RS07445	COG4585	Histidine kinase
DIJ69_RS07450	COG2197	response regulator
DIJ69_RS07455	COG3842	ATPase activity
DIJ69_RS07470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DIJ69_RS07475	COG0575	Belongs to the CDS family
DIJ69_RS07480	COG0233	cytoplasmic translational termination
DIJ69_RS07485	COG0528	UMP kinase activity
DIJ69_RS07490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DIJ69_RS07495	COG0052	Belongs to the universal ribosomal protein uS2 family
DIJ69_RS07510	COG1191	sigma factor activity
DIJ69_RS07525	COG0792	nuclease activity
DIJ69_RS07545	COG0681	Belongs to the peptidase S26 family
DIJ69_RS07550	COG0681	Belongs to the peptidase S26 family
DIJ69_RS07560	COG0335	large ribosomal subunit rRNA binding
DIJ69_RS07565	COG0336	Belongs to the RNA methyltransferase TrmD family
DIJ69_RS07570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DIJ69_RS07575	COG1837	Belongs to the UPF0109 family
DIJ69_RS07580	COG0228	four-way junction DNA binding
DIJ69_RS07600	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DIJ69_RS07635	COG0477	Major facilitator Superfamily
DIJ69_RS07640	COG1196	nuclear chromosome segregation
DIJ69_RS07655	COG1254	Belongs to the acylphosphatase family
DIJ69_RS07660	COG2340	Cysteine-rich secretory protein family
DIJ69_RS07665	COG1733	regulation of RNA biosynthetic process
DIJ69_RS07670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DIJ69_RS07675	COG0571	ribonuclease III activity
DIJ69_RS07680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DIJ69_RS07695	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DIJ69_RS07700	COG0742	ribosomal rna small subunit methyltransferase
DIJ69_RS07705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DIJ69_RS07710	COG1461	Dihydroxyacetone kinase
DIJ69_RS07715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DIJ69_RS07720	COG0351	phosphomethylpyrimidine kinase
DIJ69_RS07740	COG1181	Belongs to the D-alanine--D-alanine ligase family
DIJ69_RS07745	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DIJ69_RS07760	COG0776	regulation of translation
DIJ69_RS07770	COG0066	3-isopropylmalate dehydratase activity
DIJ69_RS07775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DIJ69_RS07780	COG1414	Transcriptional regulator
DIJ69_RS07820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DIJ69_RS07825	COG0179	Fumarylacetoacetate (FAA) hydrolase
DIJ69_RS07835	COG5002	protein histidine kinase activity
DIJ69_RS07840	COG2018	Roadblock/LC7 domain
DIJ69_RS07860	COG2018	Roadblock/LC7 domain
DIJ69_RS07880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIJ69_RS07885	COG1470	cell adhesion involved in biofilm formation
DIJ69_RS07885	COG0366	Alpha amylase catalytic
DIJ69_RS07910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIJ69_RS07915	COG1120	ATPase activity
DIJ69_RS07920	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS07925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS07965	COG0492	ferredoxin-NADP+ reductase activity
DIJ69_RS07990	COG2207	Transcriptional regulator
DIJ69_RS07990	COG3708	Transcriptional regulator
DIJ69_RS08000	COG1309	transcriptional regulator
DIJ69_RS08010	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DIJ69_RS08025	COG1472	Belongs to the glycosyl hydrolase 3 family
DIJ69_RS08035	COG0444	Belongs to the ABC transporter superfamily
DIJ69_RS08040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIJ69_RS08045	COG0601	transmembrane transport
DIJ69_RS08050	COG4608	Belongs to the ABC transporter superfamily
DIJ69_RS08060	COG1609	Transcriptional regulator
DIJ69_RS08065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DIJ69_RS08080	COG2957	Belongs to the agmatine deiminase family
DIJ69_RS08085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DIJ69_RS08090	COG0473	3-isopropylmalate dehydrogenase activity
DIJ69_RS08105	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS08110	COG0506	proline dehydrogenase activity
DIJ69_RS08115	COG2508	Transcriptional regulator
DIJ69_RS08120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIJ69_RS08145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DIJ69_RS08150	COG0440	acetolactate synthase activity
DIJ69_RS08160	COG5001	Diguanylate cyclase
DIJ69_RS08160	COG3300	MHYT domain
DIJ69_RS08170	COG0667	Aldo Keto reductase
DIJ69_RS08175	COG2133	pyrroloquinoline quinone binding
DIJ69_RS08185	COG2197	response regulator
DIJ69_RS08200	COG2409	Drug exporters of the RND superfamily
DIJ69_RS08210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DIJ69_RS08215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIJ69_RS08225	COG0154	amidase activity
DIJ69_RS08230	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIJ69_RS08240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DIJ69_RS08250	COG4221	oxidoreductase activity
DIJ69_RS08270	COG0482	sulfurtransferase activity
DIJ69_RS08305	COG0477	Major facilitator Superfamily
DIJ69_RS08320	COG2860	membrane
DIJ69_RS08325	COG4608	Belongs to the ABC transporter superfamily
DIJ69_RS08330	COG0444	Belongs to the ABC transporter superfamily
DIJ69_RS08335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIJ69_RS08340	COG0601	transmembrane transport
DIJ69_RS08345	COG0747	negative chemotaxis
DIJ69_RS08365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DIJ69_RS08370	COG0509	glycine decarboxylation via glycine cleavage system
DIJ69_RS08375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DIJ69_RS08380	COG1760	l-serine dehydratase
DIJ69_RS08400	COG4566	intracellular signal transduction
DIJ69_RS08430	COG2235	arginine
DIJ69_RS08435	COG0464	growth
DIJ69_RS08445	COG1506	peptidase
DIJ69_RS08445	COG0823	Involved in the tonB-independent uptake of proteins
DIJ69_RS08590	COG1131	(ABC) transporter
DIJ69_RS08595	COG1132	(ABC) transporter
DIJ69_RS08600	COG1132	(ABC) transporter
DIJ69_RS08605	COG1597	lipid kinase activity
DIJ69_RS08640	COG0058	SHG alpha-glucan phosphorylase activity
DIJ69_RS08645	COG0366	Alpha amylase catalytic
DIJ69_RS08650	COG0366	Alpha amylase catalytic
DIJ69_RS08655	COG3281	Trehalose synthase
DIJ69_RS08660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DIJ69_RS08670	COG3118	belongs to the thioredoxin family
DIJ69_RS08670	COG0492	ferredoxin-NADP+ reductase activity
DIJ69_RS08685	COG1301	dicarboxylic acid transport
DIJ69_RS08690	COG3290	protein histidine kinase activity
DIJ69_RS08695	COG4565	transcriptional regulatory protein
DIJ69_RS08705	COG0205	6-phosphofructokinase activity
DIJ69_RS08710	COG0857	belongs to the CobB CobQ family
DIJ69_RS08710	COG0280	phosphate acetyltransferase
DIJ69_RS08715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DIJ69_RS08750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DIJ69_RS08825	COG5000	phosphorelay sensor kinase activity
DIJ69_RS08825	COG5002	protein histidine kinase activity
DIJ69_RS08845	COG0183	Belongs to the thiolase family
DIJ69_RS08865	COG1131	(ABC) transporter
DIJ69_RS08900	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DIJ69_RS08915	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIJ69_RS08940	COG4585	Histidine kinase
DIJ69_RS08945	COG2197	response regulator
DIJ69_RS08960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DIJ69_RS08965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DIJ69_RS08970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DIJ69_RS08975	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DIJ69_RS08980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIJ69_RS08985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DIJ69_RS08990	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIJ69_RS09010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DIJ69_RS09015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIJ69_RS09025	COG2890	protein-(glutamine-N5) methyltransferase activity
DIJ69_RS09030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DIJ69_RS09035	COG0254	rRNA binding
DIJ69_RS09040	COG1316	TRANSCRIPTIONal
DIJ69_RS09055	COG0083	homoserine kinase activity
DIJ69_RS09060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DIJ69_RS09065	COG0460	homoserine dehydrogenase
DIJ69_RS09070	COG0019	diaminopimelate decarboxylase activity
DIJ69_RS09075	COG0018	arginyl-trna synthetase
DIJ69_RS09100	COG0546	phosphoglycolate phosphatase activity
DIJ69_RS09105	COG2313	pseudouridylate synthase activity
DIJ69_RS09115	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS09120	COG0662	Cupin 2, conserved barrel domain protein
DIJ69_RS09130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIJ69_RS09155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DIJ69_RS09160	COG0454	-acetyltransferase
DIJ69_RS09175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DIJ69_RS09190	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DIJ69_RS09195	COG3285	dna ligase
DIJ69_RS09195	COG1793	dna ligase
DIJ69_RS09215	COG2205	protein histidine kinase activity
DIJ69_RS09230	COG0768	penicillin binding
DIJ69_RS09235	COG0154	amidase activity
DIJ69_RS09255	COG1309	transcriptional regulator
DIJ69_RS09300	COG5002	protein histidine kinase activity
DIJ69_RS09315	COG0726	polysaccharide deacetylase
DIJ69_RS09320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DIJ69_RS09330	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS09335	COG2205	protein histidine kinase activity
DIJ69_RS09340	COG0567	Dehydrogenase, E1 component
DIJ69_RS09340	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIJ69_RS09365	COG0542	response to heat
DIJ69_RS09385	COG0604	alcohol dehydrogenase
DIJ69_RS09390	COG0281	malic enzyme
DIJ69_RS09395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIJ69_RS09400	COG0765	amino acid transport
DIJ69_RS09405	COG1126	abc transporter atp-binding protein
DIJ69_RS09410	COG4106	trans-aconitate 2-methyltransferase activity
DIJ69_RS09435	COG0659	secondary active sulfate transmembrane transporter activity
DIJ69_RS09445	COG0789	Transcriptional regulator
DIJ69_RS09455	COG4977	sequence-specific DNA binding
DIJ69_RS09525	COG0142	geranyltranstransferase activity
DIJ69_RS09530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DIJ69_RS09535	COG1959	2 iron, 2 sulfur cluster binding
DIJ69_RS09540	COG1017	nitric oxide dioxygenase activity
DIJ69_RS09540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIJ69_RS09545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DIJ69_RS09560	COG2172	sigma factor antagonist activity
DIJ69_RS09575	COG1597	lipid kinase activity
DIJ69_RS09590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DIJ69_RS09595	COG0363	glucosamine-6-phosphate deaminase activity
DIJ69_RS09600	COG1472	Belongs to the glycosyl hydrolase 3 family
DIJ69_RS09605	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS09610	COG1175	transmembrane transport
DIJ69_RS09615	COG2182	Extracellular solute-binding protein
DIJ69_RS09625	COG0667	Aldo Keto reductase
DIJ69_RS09645	COG1215	transferase activity, transferring glycosyl groups
DIJ69_RS09650	COG0109	protoheme IX farnesyltransferase activity
DIJ69_RS09655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIJ69_RS09660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIJ69_RS09670	COG1216	Glycosyl transferase, family 2
DIJ69_RS09670	COG1442	glycosyl transferase family 8
DIJ69_RS09685	COG1966	Carbon starvation protein
DIJ69_RS09715	COG1131	(ABC) transporter
DIJ69_RS09740	COG0242	peptide deformylase activity
DIJ69_RS09760	COG5662	AntiSigma factor
DIJ69_RS09765	COG1595	DNA-templated transcription, initiation
DIJ69_RS09775	COG2135	peptidase activity
DIJ69_RS09785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DIJ69_RS09790	COG1162	GTPase activity
DIJ69_RS09795	COG2076	Multidrug Resistance protein
DIJ69_RS09805	COG0483	inositol monophosphate 1-phosphatase activity
DIJ69_RS09815	COG0753	catalase activity
DIJ69_RS09840	COG1615	UPF0182 protein
DIJ69_RS09850	COG3480	Lon protease (S16) C-terminal proteolytic domain
DIJ69_RS09900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DIJ69_RS09945	COG0210	DNA helicase
DIJ69_RS10040	COG0513	Belongs to the DEAD box helicase family
DIJ69_RS10050	COG1432	Conserved Protein
DIJ69_RS10055	COG2095	MarC family integral membrane protein
DIJ69_RS10060	COG0613	PHP domain protein
DIJ69_RS10070	COG2814	Major facilitator Superfamily
DIJ69_RS10120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIJ69_RS10125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIJ69_RS10135	COG1595	DNA-templated transcription, initiation
DIJ69_RS10150	COG1024	Enoyl-CoA hydratase
DIJ69_RS10155	COG0519	Catalyzes the synthesis of GMP from XMP
DIJ69_RS10165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DIJ69_RS10170	COG1611	Belongs to the LOG family
DIJ69_RS10175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DIJ69_RS10205	COG2912	Transglutaminase-like superfamily
DIJ69_RS10210	COG2197	response regulator
DIJ69_RS10215	COG1132	(ABC) transporter
DIJ69_RS10220	COG1132	(ABC) transporter
DIJ69_RS10230	COG0515	serine threonine protein kinase
DIJ69_RS10245	COG0110	maltose O-acetyltransferase activity
DIJ69_RS10275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIJ69_RS10295	COG4608	Belongs to the ABC transporter superfamily
DIJ69_RS10300	COG0444	Belongs to the ABC transporter superfamily
DIJ69_RS10305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIJ69_RS10310	COG0601	transmembrane transport
DIJ69_RS10315	COG4166	transmembrane transport
DIJ69_RS10320	COG4608	Belongs to the ABC transporter superfamily
DIJ69_RS10330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIJ69_RS10335	COG0601	transmembrane transport
DIJ69_RS10340	COG4166	transmembrane transport
DIJ69_RS10345	COG1217	gtp-binding protein TYPA
DIJ69_RS10355	COG1609	Transcriptional regulator
DIJ69_RS10375	COG1175	transmembrane transport
DIJ69_RS10380	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS10440	COG3631	Ketosteroid isomerase-related protein
DIJ69_RS10445	COG0702	epimerase
DIJ69_RS10460	COG2208	phosphoserine phosphatase activity
DIJ69_RS10460	COG2770	Histidine kinase
DIJ69_RS10495	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS10515	COG1309	transcriptional regulator
DIJ69_RS10540	COG0463	Glycosyl transferase, family 2
DIJ69_RS10550	COG1842	Phage shock protein A
DIJ69_RS10635	COG0012	GTP binding
DIJ69_RS10650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DIJ69_RS10660	COG1570	exodeoxyribonuclease VII activity
DIJ69_RS10665	COG1722	exodeoxyribonuclease VII activity
DIJ69_RS10670	COG0778	Nitroreductase
DIJ69_RS10695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DIJ69_RS10695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DIJ69_RS10720	COG1362	aminopeptidase activity
DIJ69_RS10735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIJ69_RS10745	COG0114	fumarate hydratase activity
DIJ69_RS10780	COG1136	(ABC) transporter
DIJ69_RS10795	COG0450	alkyl hydroperoxide reductase
DIJ69_RS10800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIJ69_RS10815	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DIJ69_RS10820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIJ69_RS10825	COG0667	Aldo Keto reductase
DIJ69_RS10885	COG2885	chlorophyll binding
DIJ69_RS10905	COG2197	response regulator
DIJ69_RS10940	COG2894	cell division
DIJ69_RS10980	COG0251	oxidation-reduction process
DIJ69_RS10985	COG1414	Transcriptional regulator
DIJ69_RS11000	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DIJ69_RS11020	COG1733	regulation of RNA biosynthetic process
DIJ69_RS11040	COG0436	Aminotransferase
DIJ69_RS11055	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DIJ69_RS11065	COG1331	Highly conserved protein containing a thioredoxin domain
DIJ69_RS11085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIJ69_RS11095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DIJ69_RS11110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DIJ69_RS11115	COG2255	four-way junction helicase activity
DIJ69_RS11120	COG1366	Belongs to the anti-sigma-factor antagonist family
DIJ69_RS11125	COG1366	Belongs to the anti-sigma-factor antagonist family
DIJ69_RS11130	COG2172	sigma factor antagonist activity
DIJ69_RS11140	COG3437	response regulator, receiver
DIJ69_RS11140	COG4999	Histidine kinase
DIJ69_RS11140	COG2205	protein histidine kinase activity
DIJ69_RS11140	COG3850	Histidine kinase
DIJ69_RS11145	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS11185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIJ69_RS11200	COG1396	sequence-specific DNA binding
DIJ69_RS11205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DIJ69_RS11225	COG1376	ErfK ybiS ycfS ynhG family protein
DIJ69_RS11250	COG1024	Enoyl-CoA hydratase
DIJ69_RS11265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIJ69_RS11275	COG0424	maF-like protein
DIJ69_RS11285	COG4770	biotin carboxylase activity
DIJ69_RS11315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIJ69_RS11330	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS11370	COG1595	DNA-templated transcription, initiation
DIJ69_RS11375	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS11380	COG2205	protein histidine kinase activity
DIJ69_RS11405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DIJ69_RS11420	COG0583	DNA-binding transcription factor activity
DIJ69_RS11425	COG2814	Major facilitator Superfamily
DIJ69_RS11445	COG1404	Belongs to the peptidase S8 family
DIJ69_RS11470	COG1079	Belongs to the binding-protein-dependent transport system permease family
DIJ69_RS11475	COG4603	Belongs to the binding-protein-dependent transport system permease family
DIJ69_RS11480	COG3845	ABC transporter
DIJ69_RS11485	COG1744	ABC transporter substrate-binding protein PnrA-like
DIJ69_RS11490	COG1473	amidohydrolase
DIJ69_RS11490	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DIJ69_RS11500	COG2089	acid synthase
DIJ69_RS11505	COG1083	cytidylyl-transferase
DIJ69_RS11515	COG1216	Glycosyl transferase, family 2
DIJ69_RS11545	COG1216	Glycosyl transferase, family 2
DIJ69_RS11570	COG1595	DNA-templated transcription, initiation
DIJ69_RS11575	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DIJ69_RS11580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DIJ69_RS11585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DIJ69_RS11640	COG2009	succinate dehydrogenase
DIJ69_RS11655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DIJ69_RS11690	COG1408	metallophosphoesterase
DIJ69_RS11705	COG1295	ribonuclease BN
DIJ69_RS11725	COG0180	Tryptophanyl-tRNA synthetase
DIJ69_RS11730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIJ69_RS11735	COG0754	glutathionylspermidine amidase activity
DIJ69_RS11745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIJ69_RS11750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIJ69_RS11770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DIJ69_RS11785	COG0138	bifunctional purine biosynthesis protein purh
DIJ69_RS11815	COG0045	succinate-CoA ligase (ADP-forming) activity
DIJ69_RS11830	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DIJ69_RS11840	COG0714	Associated with various cellular activities
DIJ69_RS11860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DIJ69_RS11875	COG0739	heme binding
DIJ69_RS11895	COG0791	NLP P60 protein
DIJ69_RS11900	COG2197	response regulator
DIJ69_RS11960	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS11965	COG0515	serine threonine protein kinase
DIJ69_RS11965	COG2815	serine threonine protein kinase
DIJ69_RS11970	COG0515	serine threonine protein kinase
DIJ69_RS12000	COG0516	GMP reductase activity
DIJ69_RS12010	COG1595	DNA-templated transcription, initiation
DIJ69_RS12025	COG0583	DNA-binding transcription factor activity
DIJ69_RS12050	COG1609	Transcriptional regulator
DIJ69_RS12065	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS12080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DIJ69_RS12090	COG0726	polysaccharide deacetylase
DIJ69_RS12115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DIJ69_RS12140	COG0802	atpase or kinase
DIJ69_RS12150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DIJ69_RS12155	COG3189	MarR family transcriptional regulator
DIJ69_RS12160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DIJ69_RS12160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DIJ69_RS12165	COG0736	holo-[acyl-carrier-protein] synthase activity
DIJ69_RS12170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DIJ69_RS12180	COG4941	Belongs to the sigma-70 factor family
DIJ69_RS12185	COG3795	YCII-related domain
DIJ69_RS12190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS12195	COG0596	Alpha beta hydrolase
DIJ69_RS12210	COG1309	transcriptional regulator
DIJ69_RS12255	COG1072	(Pantothenic acid kinase))
DIJ69_RS12265	COG2208	phosphoserine phosphatase activity
DIJ69_RS12265	COG2770	Histidine kinase
DIJ69_RS12270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIJ69_RS12275	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DIJ69_RS12280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DIJ69_RS12285	COG0488	(ABC) transporter
DIJ69_RS12295	COG0101	tRNA pseudouridine synthase activity
DIJ69_RS12300	COG0203	ribosomal protein L17
DIJ69_RS12305	COG0202	RNA polymerase activity
DIJ69_RS12310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DIJ69_RS12315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DIJ69_RS12320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DIJ69_RS12325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DIJ69_RS12335	COG0563	adenylate kinase activity
DIJ69_RS12345	COG0200	Binds to the 23S rRNA
DIJ69_RS12360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DIJ69_RS12365	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DIJ69_RS12380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DIJ69_RS12385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DIJ69_RS12390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DIJ69_RS12395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DIJ69_RS12400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DIJ69_RS12405	COG0255	Belongs to the universal ribosomal protein uL29 family
DIJ69_RS12410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DIJ69_RS12415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DIJ69_RS12420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DIJ69_RS12425	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DIJ69_RS12430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DIJ69_RS12435	COG0089	rRNA binding
DIJ69_RS12440	COG0088	Forms part of the polypeptide exit tunnel
DIJ69_RS12445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DIJ69_RS12450	COG0051	transcription antitermination factor activity, RNA binding
DIJ69_RS12470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DIJ69_RS12475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DIJ69_RS12480	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DIJ69_RS12485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIJ69_RS12490	COG0085	RNA polymerase activity
DIJ69_RS12500	COG0222	ribosome binding
DIJ69_RS12505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DIJ69_RS12515	COG0081	regulation of translation
DIJ69_RS12520	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DIJ69_RS12540	COG0436	Aminotransferase
DIJ69_RS12545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DIJ69_RS12560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DIJ69_RS12570	COG2030	dehydratase
DIJ69_RS12575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DIJ69_RS12595	COG0702	epimerase
DIJ69_RS12610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DIJ69_RS12625	COG3304	Inner membrane component domain
DIJ69_RS12630	COG0501	Belongs to the peptidase M48B family
DIJ69_RS12640	COG1007	ATP synthesis coupled electron transport
DIJ69_RS12650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIJ69_RS12655	COG0713	ATP synthesis coupled electron transport
DIJ69_RS12660	COG0839	Belongs to the complex I subunit 6 family
DIJ69_RS12665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIJ69_RS12670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DIJ69_RS12675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIJ69_RS12680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIJ69_RS12685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIJ69_RS12705	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DIJ69_RS12705	COG0674	pyruvate-flavodoxin oxidoreductase activity
DIJ69_RS12710	COG1013	pyruvate-flavodoxin oxidoreductase activity
DIJ69_RS12715	COG1733	regulation of RNA biosynthetic process
DIJ69_RS12720	COG0702	epimerase
DIJ69_RS12760	COG1064	alcohol dehydrogenase
DIJ69_RS12780	COG0583	DNA-binding transcription factor activity
DIJ69_RS12785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DIJ69_RS12840	COG0561	phosphatase activity
DIJ69_RS12860	COG1917	Cupin 2, conserved barrel domain protein
DIJ69_RS12865	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DIJ69_RS12865	COG0515	serine threonine protein kinase
DIJ69_RS12895	COG0142	geranyltranstransferase activity
DIJ69_RS12900	COG3104	oligopeptide transport
DIJ69_RS12910	COG0179	Fumarylacetoacetate (FAA) hydrolase
DIJ69_RS12935	COG2197	response regulator
DIJ69_RS12945	COG0596	Alpha beta hydrolase
DIJ69_RS12960	COG1007	ATP synthesis coupled electron transport
DIJ69_RS12970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIJ69_RS12975	COG0713	ATP synthesis coupled electron transport
DIJ69_RS12980	COG0839	Belongs to the complex I subunit 6 family
DIJ69_RS12985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIJ69_RS12990	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DIJ69_RS12995	COG1034	ATP synthesis coupled electron transport
DIJ69_RS13010	COG0649	NAD binding
DIJ69_RS13015	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIJ69_RS13020	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIJ69_RS13060	COG2226	methyltransferase
DIJ69_RS13065	COG2175	clavaminate synthase activity
DIJ69_RS13090	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DIJ69_RS13100	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DIJ69_RS13105	COG1278	Cold shock
DIJ69_RS13180	COG1309	transcriptional regulator
DIJ69_RS13190	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS13210	COG0259	pyridoxamine-phosphate oxidase activity
DIJ69_RS13215	COG0501	Belongs to the peptidase M48B family
DIJ69_RS13235	COG2072	flavoprotein involved in K transport
DIJ69_RS13270	COG1024	Enoyl-CoA hydratase
DIJ69_RS13275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIJ69_RS13315	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS13320	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS13335	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS13340	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS13350	COG0318	PFAM AMP-dependent synthetase and ligase
DIJ69_RS13360	COG1366	Belongs to the anti-sigma-factor antagonist family
DIJ69_RS13405	COG1131	(ABC) transporter
DIJ69_RS13415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DIJ69_RS13425	COG4821	SIS domain
DIJ69_RS13430	COG2205	protein histidine kinase activity
DIJ69_RS13435	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS13450	COG0577	efflux transmembrane transporter activity
DIJ69_RS13450	COG1136	(ABC) transporter
DIJ69_RS13455	COG0577	efflux transmembrane transporter activity
DIJ69_RS13455	COG1136	(ABC) transporter
DIJ69_RS13470	COG0259	pyridoxamine-phosphate oxidase activity
DIJ69_RS13535	COG1024	Enoyl-CoA hydratase
DIJ69_RS13540	COG0318	PFAM AMP-dependent synthetase and ligase
DIJ69_RS13555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIJ69_RS13570	COG2318	DinB family
DIJ69_RS13575	COG1051	belongs to the nudix hydrolase family
DIJ69_RS13580	COG5006	permease, DMT superfamily
DIJ69_RS13585	COG0583	DNA-binding transcription factor activity
DIJ69_RS13595	COG2207	Transcriptional regulator
DIJ69_RS13600	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DIJ69_RS13605	COG0300	oxidoreductase activity
DIJ69_RS13605	COG0318	PFAM AMP-dependent synthetase and ligase
DIJ69_RS13605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIJ69_RS13605	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS13605	COG3321	synthase
DIJ69_RS13625	COG2124	cytochrome p450
DIJ69_RS13640	COG0583	DNA-binding transcription factor activity
DIJ69_RS13660	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DIJ69_RS13675	COG0247	lactate metabolic process
DIJ69_RS13675	COG0277	FAD linked oxidase domain protein
DIJ69_RS13680	COG2205	protein histidine kinase activity
DIJ69_RS13710	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DIJ69_RS13725	COG2226	methyltransferase
DIJ69_RS13790	COG1309	transcriptional regulator
DIJ69_RS13810	COG2197	response regulator
DIJ69_RS13830	COG1132	(ABC) transporter
DIJ69_RS13835	COG1132	(ABC) transporter
DIJ69_RS13940	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS13950	COG0515	serine threonine protein kinase
DIJ69_RS13960	COG2267	carboxylic ester hydrolase activity
DIJ69_RS13990	COG0671	phosphoesterase, PA-phosphatase related
DIJ69_RS14005	COG0667	Aldo Keto reductase
DIJ69_RS14035	COG2252	PERMEase
DIJ69_RS14045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DIJ69_RS14070	COG2814	Major facilitator Superfamily
DIJ69_RS14080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DIJ69_RS14085	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DIJ69_RS14095	COG1278	Cold shock
DIJ69_RS14135	COG1061	Type III restriction enzyme res subunit
DIJ69_RS14145	COG3973	AAA domain
DIJ69_RS14150	COG3142	Participates in the control of copper homeostasis
DIJ69_RS14160	COG1984	allophanate hydrolase subunit 2
DIJ69_RS14170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DIJ69_RS14205	COG1737	Transcriptional regulator
DIJ69_RS14210	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DIJ69_RS14215	COG1263	PTS System
DIJ69_RS14215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIJ69_RS14240	COG4251	negative regulation of phosphorylation
DIJ69_RS14265	COG1175	transmembrane transport
DIJ69_RS14270	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS14360	COG0604	alcohol dehydrogenase
DIJ69_RS14360	COG3321	synthase
DIJ69_RS14360	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS14390	COG1595	DNA-templated transcription, initiation
DIJ69_RS14395	COG1132	(ABC) transporter
DIJ69_RS14445	COG0463	Glycosyl transferase, family 2
DIJ69_RS14450	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DIJ69_RS14465	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DIJ69_RS14520	COG0513	Belongs to the DEAD box helicase family
DIJ69_RS14525	COG1278	Cold shock
DIJ69_RS14550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DIJ69_RS14555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DIJ69_RS14560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DIJ69_RS14560	COG1754	DNA topoisomerase type I activity
DIJ69_RS14570	COG2890	protein-(glutamine-N5) methyltransferase activity
DIJ69_RS14580	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DIJ69_RS14585	COG2172	sigma factor antagonist activity
DIJ69_RS14590	COG1366	Belongs to the anti-sigma-factor antagonist family
DIJ69_RS14595	COG1111	helicase
DIJ69_RS14595	COG1205	dead DEAH box helicase
DIJ69_RS14655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIJ69_RS14660	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DIJ69_RS14670	COG2267	carboxylic ester hydrolase activity
DIJ69_RS14700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIJ69_RS14725	COG0003	Pfam Anion-transporting ATPase
DIJ69_RS14740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DIJ69_RS14745	COG1610	YqeY-like protein
DIJ69_RS14750	COG1408	metallophosphoesterase
DIJ69_RS14855	COG1937	Protein conserved in bacteria
DIJ69_RS14870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIJ69_RS14870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DIJ69_RS14935	COG2755	lipolytic protein G-D-S-L family
DIJ69_RS14945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DIJ69_RS14970	COG1595	DNA-templated transcription, initiation
DIJ69_RS14995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DIJ69_RS15000	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DIJ69_RS15015	COG1802	Transcriptional regulator
DIJ69_RS15020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DIJ69_RS15025	COG0693	protein deglycase activity
DIJ69_RS15035	COG0515	serine threonine protein kinase
DIJ69_RS15035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DIJ69_RS15040	COG0738	Major facilitator superfamily
DIJ69_RS15045	COG3226	Transcriptional regulator
DIJ69_RS15160	COG0592	DNA-directed DNA polymerase activity
DIJ69_RS15175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DIJ69_RS15200	COG2197	response regulator
DIJ69_RS15205	COG4585	Histidine kinase
DIJ69_RS15210	COG0702	epimerase
DIJ69_RS15220	COG3844	kynureninase activity
DIJ69_RS15235	COG0477	Major facilitator Superfamily
DIJ69_RS15240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DIJ69_RS15245	COG0191	fructose-bisphosphate aldolase activity
DIJ69_RS15250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DIJ69_RS15265	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DIJ69_RS15290	COG0542	response to heat
DIJ69_RS15340	COG0612	Peptidase, M16
DIJ69_RS15345	COG2226	methyltransferase
DIJ69_RS15365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DIJ69_RS15385	COG2197	response regulator
DIJ69_RS15405	COG0789	Transcriptional regulator
DIJ69_RS15410	COG0484	heat shock protein binding
DIJ69_RS15415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DIJ69_RS15420	COG0443	Heat shock 70 kDa protein
DIJ69_RS15425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DIJ69_RS15430	COG0247	lactate metabolic process
DIJ69_RS15430	COG2181	nitrate reductase activity
DIJ69_RS15450	COG0717	Belongs to the dCTP deaminase family
DIJ69_RS15610	COG3209	COG3209 Rhs family protein
DIJ69_RS15655	COG0277	FAD linked oxidase domain protein
DIJ69_RS15785	COG2205	protein histidine kinase activity
DIJ69_RS15790	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS15805	COG1609	Transcriptional regulator
DIJ69_RS15830	COG2124	cytochrome p450
DIJ69_RS15860	COG3585	molybdate ion transport
DIJ69_RS15885	COG0531	amino acid
DIJ69_RS15895	COG0475	glutathione-regulated potassium exporter activity
DIJ69_RS15905	COG2409	Drug exporters of the RND superfamily
DIJ69_RS15910	COG3594	Acyltransferase
DIJ69_RS15920	COG0513	Belongs to the DEAD box helicase family
DIJ69_RS15925	COG1278	Cold shock
DIJ69_RS15985	COG2268	Band 7 protein
DIJ69_RS16015	COG4941	Belongs to the sigma-70 factor family
DIJ69_RS16040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DIJ69_RS16100	COG1191	sigma factor activity
DIJ69_RS16105	COG1191	sigma factor activity
DIJ69_RS16130	COG2353	YceI-like domain
DIJ69_RS16135	COG3467	pyridoxamine 5'-phosphate
DIJ69_RS16150	COG0477	Major facilitator Superfamily
DIJ69_RS16165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DIJ69_RS16170	COG1215	transferase activity, transferring glycosyl groups
DIJ69_RS16175	COG2205	protein histidine kinase activity
DIJ69_RS16180	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS16200	COG1595	DNA-templated transcription, initiation
DIJ69_RS16205	COG1252	NADH dehydrogenase
DIJ69_RS16210	COG3629	intracellular signal transduction
DIJ69_RS16210	COG3903	Transcriptional regulator
DIJ69_RS16240	COG1595	DNA-templated transcription, initiation
DIJ69_RS16265	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS16280	COG3693	PFAM glycoside hydrolase, family 10
DIJ69_RS16315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIJ69_RS16350	COG0006	proline dipeptidase activity
DIJ69_RS16370	COG1999	signal sequence binding
DIJ69_RS16380	COG2372	response to copper ion
DIJ69_RS16385	COG2837	iron assimilation
DIJ69_RS16390	COG0077	Prephenate dehydratase
DIJ69_RS16395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DIJ69_RS16425	COG1131	(ABC) transporter
DIJ69_RS16440	COG0789	Transcriptional regulator
DIJ69_RS16445	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DIJ69_RS16455	COG0561	phosphatase activity
DIJ69_RS16465	COG4988	ABC transporter
DIJ69_RS16470	COG1294	oxidase, subunit
DIJ69_RS16475	COG1271	oxidase subunit
DIJ69_RS16485	COG1609	Transcriptional regulator
DIJ69_RS16490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DIJ69_RS16500	COG3152	Membrane
DIJ69_RS16510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DIJ69_RS16535	COG0662	Cupin 2, conserved barrel domain protein
DIJ69_RS16540	COG1950	PFAM Membrane protein of
DIJ69_RS16565	COG2814	Major facilitator Superfamily
DIJ69_RS16585	COG2945	thiolester hydrolase activity
DIJ69_RS16585	COG0596	Alpha beta hydrolase
DIJ69_RS16595	COG0305	Participates in initiation and elongation during chromosome replication
DIJ69_RS16605	COG0359	binds to the 23S rRNA
DIJ69_RS16610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DIJ69_RS16615	COG0629	single-stranded DNA binding
DIJ69_RS16620	COG0360	Binds together with S18 to 16S ribosomal RNA
DIJ69_RS16645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DIJ69_RS16665	COG0617	tRNA 3'-terminal CCA addition
DIJ69_RS16680	COG0515	serine threonine protein kinase
DIJ69_RS16680	COG2815	serine threonine protein kinase
DIJ69_RS16685	COG1595	DNA-templated transcription, initiation
DIJ69_RS16695	COG0492	ferredoxin-NADP+ reductase activity
DIJ69_RS16700	COG3118	belongs to the thioredoxin family
DIJ69_RS16715	COG1192	Involved in chromosome partitioning
DIJ69_RS16720	COG0357	Ribosomal RNA small subunit methyltransferase G
DIJ69_RS16730	COG0706	membrane insertase activity
DIJ69_RS16735	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DIJ69_RS16740	COG0594	ribonuclease P activity
DIJ69_RS16745	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DIJ69_RS16760	COG0592	DNA-directed DNA polymerase activity
DIJ69_RS16765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DIJ69_RS16770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DIJ69_RS16775	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DIJ69_RS16785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIJ69_RS16825	COG0515	serine threonine protein kinase
DIJ69_RS16855	COG0705	Rhomboid family
DIJ69_RS16870	COG3764	Sortase (surface protein transpeptidase)
DIJ69_RS16885	COG3764	Sortase (surface protein transpeptidase)
DIJ69_RS16890	COG3764	Sortase (surface protein transpeptidase)
DIJ69_RS16895	COG0515	serine threonine protein kinase
DIJ69_RS16900	COG0768	penicillin binding
DIJ69_RS16915	COG1716	ATPase activity
DIJ69_RS16920	COG1716	ATPase activity
DIJ69_RS16935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DIJ69_RS16940	COG1733	regulation of RNA biosynthetic process
DIJ69_RS16965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIJ69_RS16970	COG2151	metal-sulfur cluster biosynthetic enzyme
DIJ69_RS16975	COG3396	Phenylacetate-CoA oxygenase
DIJ69_RS16980	COG3460	Phenylacetate-CoA oxygenase
DIJ69_RS16985	COG3396	Phenylacetate-CoA oxygenase
DIJ69_RS17010	COG1309	transcriptional regulator
DIJ69_RS17015	COG1522	sequence-specific DNA binding
DIJ69_RS17065	COG1136	(ABC) transporter
DIJ69_RS17065	COG4591	ABC-type transport system involved in lipoprotein release permease component
DIJ69_RS17080	COG0515	serine threonine protein kinase
DIJ69_RS17085	COG0515	serine threonine protein kinase
DIJ69_RS17110	COG0022	dehydrogenase e1 component
DIJ69_RS17115	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIJ69_RS17145	COG2271	Major facilitator Superfamily
DIJ69_RS17155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIJ69_RS17175	COG1362	aminopeptidase activity
DIJ69_RS17180	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS17190	COG1741	Belongs to the pirin family
DIJ69_RS17205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DIJ69_RS17215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIJ69_RS17220	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS17225	COG2205	protein histidine kinase activity
DIJ69_RS17230	COG2304	oxidoreductase activity
DIJ69_RS17260	COG0431	NADPH-dependent FMN reductase
DIJ69_RS17280	COG1672	PFAM Archaeal ATPase
DIJ69_RS17280	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DIJ69_RS17295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS17300	COG0180	Tryptophanyl-tRNA synthetase
DIJ69_RS17310	COG2255	four-way junction helicase activity
DIJ69_RS17335	COG0181	hydroxymethylbilane synthase activity
DIJ69_RS17340	COG0475	glutathione-regulated potassium exporter activity
DIJ69_RS17345	COG0490	domain, Protein
DIJ69_RS17370	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DIJ69_RS17460	COG0151	Belongs to the GarS family
DIJ69_RS17475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DIJ69_RS17485	COG2197	response regulator
DIJ69_RS17520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DIJ69_RS17525	COG0047	phosphoribosylformylglycinamidine synthase activity
DIJ69_RS17530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DIJ69_RS17540	COG0741	lytic transglycosylase activity
DIJ69_RS17540	COG0739	heme binding
DIJ69_RS17540	COG1196	nuclear chromosome segregation
DIJ69_RS17560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DIJ69_RS17570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DIJ69_RS17595	COG1643	Atp-dependent helicase
DIJ69_RS17605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DIJ69_RS17605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DIJ69_RS17610	COG0785	Cytochrome C biogenesis protein
DIJ69_RS17640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DIJ69_RS17645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DIJ69_RS17655	COG0513	Belongs to the DEAD box helicase family
DIJ69_RS17705	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DIJ69_RS17710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DIJ69_RS17720	COG0789	Transcriptional regulator
DIJ69_RS17730	COG0739	heme binding
DIJ69_RS17730	COG0741	lytic transglycosylase activity
DIJ69_RS17730	COG1196	nuclear chromosome segregation
DIJ69_RS17735	COG0667	Aldo Keto reductase
DIJ69_RS17745	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DIJ69_RS17750	COG0579	oxidoreductase
DIJ69_RS17775	COG1252	NADH dehydrogenase
DIJ69_RS17790	COG1846	Transcriptional regulator
DIJ69_RS17815	COG2197	response regulator
DIJ69_RS17830	COG1131	(ABC) transporter
DIJ69_RS17900	COG0739	heme binding
DIJ69_RS17900	COG1196	nuclear chromosome segregation
DIJ69_RS17900	COG0741	lytic transglycosylase activity
DIJ69_RS17905	COG0671	phosphoesterase, PA-phosphatase related
DIJ69_RS17935	COG0306	phosphate transporter
DIJ69_RS17955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DIJ69_RS17960	COG0406	alpha-ribazole phosphatase activity
DIJ69_RS17960	COG0494	nUDIX hydrolase
DIJ69_RS17985	COG1725	Transcriptional regulator
DIJ69_RS17995	COG0456	acetyltransferase
DIJ69_RS18000	COG0737	Belongs to the 5'-nucleotidase family
DIJ69_RS18050	COG0739	heme binding
DIJ69_RS18085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIJ69_RS18090	COG1609	Transcriptional regulator
DIJ69_RS18095	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS18120	COG2897	thiosulfate sulfurtransferase activity
DIJ69_RS18160	COG3485	protocatechuate 3,4-dioxygenase
DIJ69_RS18165	COG0735	belongs to the Fur family
DIJ69_RS18175	COG1490	D-aminoacyl-tRNA deacylase activity
DIJ69_RS18190	COG4552	Acetyltransferase involved in intracellular survival and related
DIJ69_RS18230	COG0789	Transcriptional regulator
DIJ69_RS18265	COG0438	transferase activity, transferring glycosyl groups
DIJ69_RS18315	COG0588	phosphoglycerate mutase activity
DIJ69_RS18330	COG5002	protein histidine kinase activity
DIJ69_RS18350	COG1329	Transcriptional regulator
DIJ69_RS18355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DIJ69_RS18360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DIJ69_RS18365	COG3467	pyridoxamine 5'-phosphate
DIJ69_RS18370	COG0215	cysteine-tRNA ligase activity
DIJ69_RS18385	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DIJ69_RS18395	COG3842	ATPase activity
DIJ69_RS18445	COG2208	phosphoserine phosphatase activity
DIJ69_RS18445	COG2770	Histidine kinase
DIJ69_RS18500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIJ69_RS18515	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DIJ69_RS18535	COG2197	response regulator
DIJ69_RS18540	COG4585	Histidine kinase
DIJ69_RS18550	COG0666	response to abiotic stimulus
DIJ69_RS18575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DIJ69_RS18600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DIJ69_RS18685	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS18715	COG0076	glutamate decarboxylase activity
DIJ69_RS18720	COG0655	NAD(P)H dehydrogenase (quinone) activity
DIJ69_RS18730	COG0393	Putative heavy-metal-binding
DIJ69_RS18735	COG0586	Pfam SNARE associated Golgi protein
DIJ69_RS18745	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DIJ69_RS18750	COG2027	D-alanyl-D-alanine carboxypeptidase
DIJ69_RS18775	COG0302	gtp cyclohydrolase
DIJ69_RS18785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DIJ69_RS18790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DIJ69_RS18805	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DIJ69_RS18805	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DIJ69_RS18815	COG0517	IMP dehydrogenase activity
DIJ69_RS18815	COG1125	glycine betaine transport
DIJ69_RS18820	COG1174	glycine betaine transport
DIJ69_RS18825	COG1174	glycine betaine transport
DIJ69_RS18840	COG0649	NAD binding
DIJ69_RS18855	COG2197	response regulator
DIJ69_RS18880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DIJ69_RS18885	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DIJ69_RS18895	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DIJ69_RS18915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DIJ69_RS18950	COG0739	heme binding
DIJ69_RS18955	COG2205	protein histidine kinase activity
DIJ69_RS18960	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS18970	COG1595	DNA-templated transcription, initiation
DIJ69_RS18975	COG1194	a g-specific adenine glycosylase
DIJ69_RS18985	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DIJ69_RS19005	COG0248	Ppx GppA phosphatase
DIJ69_RS19010	COG1082	Xylose isomerase domain protein TIM barrel
DIJ69_RS19020	COG0129	dihydroxy-acid dehydratase activity
DIJ69_RS19025	COG0515	serine threonine protein kinase
DIJ69_RS19025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DIJ69_RS19030	COG4991	sh3 domain protein
DIJ69_RS19040	COG0842	Transport permease protein
DIJ69_RS19040	COG1129	ABC transporter
DIJ69_RS19050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DIJ69_RS19075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DIJ69_RS19080	COG2223	nitrite transmembrane transporter activity
DIJ69_RS19135	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DIJ69_RS19140	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DIJ69_RS19145	COG0181	hydroxymethylbilane synthase activity
DIJ69_RS19150	COG1648	precorrin-2 dehydrogenase activity
DIJ69_RS19150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DIJ69_RS19155	COG0113	porphobilinogen synthase activity
DIJ69_RS19195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DIJ69_RS19200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIJ69_RS19230	COG0789	Transcriptional regulator
DIJ69_RS19235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIJ69_RS19245	COG0018	arginyl-trna synthetase
DIJ69_RS19250	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DIJ69_RS19270	COG1690	Belongs to the RtcB family
DIJ69_RS19280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DIJ69_RS19305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DIJ69_RS19320	COG1116	anion transmembrane transporter activity
DIJ69_RS19350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DIJ69_RS19355	COG0406	alpha-ribazole phosphatase activity
DIJ69_RS19375	COG0785	Cytochrome C biogenesis protein
DIJ69_RS19380	COG1333	cytochrome c biogenesis protein
DIJ69_RS19385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DIJ69_RS19395	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DIJ69_RS19400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DIJ69_RS19445	COG1309	transcriptional regulator
DIJ69_RS19450	COG3647	Membrane
DIJ69_RS19460	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS19495	COG3940	Belongs to the glycosyl hydrolase 43 family
DIJ69_RS19520	COG0667	Aldo Keto reductase
DIJ69_RS19530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIJ69_RS19535	COG1802	Transcriptional regulator
DIJ69_RS19540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIJ69_RS19555	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS19575	COG1653	transport
DIJ69_RS19580	COG2755	lipolytic protein G-D-S-L family
DIJ69_RS19585	COG3866	Pectate lyase
DIJ69_RS19590	COG4677	pectinesterase activity
DIJ69_RS19615	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DIJ69_RS19660	COG0768	penicillin binding
DIJ69_RS19670	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DIJ69_RS19710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DIJ69_RS19750	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS19775	COG1686	Belongs to the peptidase S11 family
DIJ69_RS19805	COG1309	transcriptional regulator
DIJ69_RS19830	COG1846	Transcriptional regulator
DIJ69_RS19835	COG3384	dioxygenase
DIJ69_RS19850	COG0477	Major facilitator Superfamily
DIJ69_RS19870	COG0243	molybdopterin cofactor binding
DIJ69_RS19875	COG0437	4 iron, 4 sulfur cluster binding
DIJ69_RS19895	COG1970	mechanosensitive ion channel activity
DIJ69_RS19905	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DIJ69_RS19930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DIJ69_RS19935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DIJ69_RS19945	COG0315	cyclic pyranopterin monophosphate synthase activity
DIJ69_RS19950	COG0521	Mo-molybdopterin cofactor biosynthetic process
DIJ69_RS19955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIJ69_RS20010	COG0419	ATPase involved in DNA repair
DIJ69_RS20025	COG0419	ATPase involved in DNA repair
DIJ69_RS20055	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DIJ69_RS20085	COG0708	Exodeoxyribonuclease III
DIJ69_RS20095	COG2072	flavoprotein involved in K transport
DIJ69_RS20105	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS20120	COG0793	Belongs to the peptidase S41A family
DIJ69_RS20120	COG4946	Tricorn protease homolog
DIJ69_RS20130	COG2409	Drug exporters of the RND superfamily
DIJ69_RS20150	COG0310	cobalt ion transport
DIJ69_RS20160	COG1122	ATPase activity
DIJ69_RS20165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIJ69_RS20190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIJ69_RS20195	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
DIJ69_RS20230	COG1115	amino acid carrier protein
DIJ69_RS20240	COG0442	prolyl-tRNA aminoacylation
DIJ69_RS20295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIJ69_RS20320	COG0084	hydrolase, TatD family'
DIJ69_RS20330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DIJ69_RS20335	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DIJ69_RS20345	COG0488	(ABC) transporter
DIJ69_RS20375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIJ69_RS20390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DIJ69_RS20400	COG2197	response regulator
DIJ69_RS20405	COG1846	Transcriptional regulator
DIJ69_RS20410	COG4106	trans-aconitate 2-methyltransferase activity
DIJ69_RS20435	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DIJ69_RS20445	COG0193	aminoacyl-tRNA hydrolase activity
DIJ69_RS20455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIJ69_RS20460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DIJ69_RS20470	COG4585	Histidine kinase
DIJ69_RS20505	COG2124	cytochrome p450
DIJ69_RS20545	COG0346	lactoylglutathione lyase activity
DIJ69_RS20550	COG0640	Transcriptional regulator
DIJ69_RS20565	COG2814	Major facilitator Superfamily
DIJ69_RS20570	COG1136	(ABC) transporter
DIJ69_RS20585	COG3629	intracellular signal transduction
DIJ69_RS20585	COG3903	Transcriptional regulator
DIJ69_RS20640	COG1473	amidohydrolase
DIJ69_RS20710	COG0515	serine threonine protein kinase
DIJ69_RS20710	COG2815	serine threonine protein kinase
DIJ69_RS20730	COG1652	LysM domain
DIJ69_RS20740	COG0148	phosphopyruvate hydratase activity
DIJ69_RS20760	COG1252	NADH dehydrogenase
DIJ69_RS20765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DIJ69_RS20770	COG1136	(ABC) transporter
DIJ69_RS20770	COG0577	efflux transmembrane transporter activity
DIJ69_RS20775	COG0577	efflux transmembrane transporter activity
DIJ69_RS20775	COG1136	(ABC) transporter
DIJ69_RS20800	COG0183	Belongs to the thiolase family
DIJ69_RS20805	COG2755	lipolytic protein G-D-S-L family
DIJ69_RS20850	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DIJ69_RS20865	COG1228	amidohydrolase
DIJ69_RS20870	COG1191	sigma factor activity
DIJ69_RS20875	COG1366	Belongs to the anti-sigma-factor antagonist family
DIJ69_RS20905	COG3104	oligopeptide transport
DIJ69_RS20910	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS20915	COG2205	protein histidine kinase activity
DIJ69_RS20950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DIJ69_RS20980	COG2226	methyltransferase
DIJ69_RS21020	COG1316	TRANSCRIPTIONal
DIJ69_RS21030	COG1316	TRANSCRIPTIONal
DIJ69_RS21045	COG1316	TRANSCRIPTIONal
DIJ69_RS21050	COG1316	TRANSCRIPTIONal
DIJ69_RS21065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DIJ69_RS21075	COG0778	Nitroreductase
DIJ69_RS21075	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DIJ69_RS21080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DIJ69_RS21115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIJ69_RS21120	COG2835	tetraacyldisaccharide 4'-kinase activity
DIJ69_RS21140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DIJ69_RS21185	COG0714	Associated with various cellular activities
DIJ69_RS21205	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DIJ69_RS21210	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS21215	COG5000	phosphorelay sensor kinase activity
DIJ69_RS21215	COG5002	protein histidine kinase activity
DIJ69_RS21220	COG0823	Involved in the tonB-independent uptake of proteins
DIJ69_RS21230	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DIJ69_RS21235	COG2197	response regulator
DIJ69_RS21280	COG1134	teichoic acid transport
DIJ69_RS21290	COG1309	transcriptional regulator
DIJ69_RS21300	COG1216	Glycosyl transferase, family 2
DIJ69_RS21305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DIJ69_RS21310	COG2226	methyltransferase
DIJ69_RS21310	COG1073	alpha beta
DIJ69_RS21320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DIJ69_RS21325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DIJ69_RS21330	COG0438	transferase activity, transferring glycosyl groups
DIJ69_RS21335	COG1216	Glycosyl transferase, family 2
DIJ69_RS21335	COG1442	glycosyl transferase family 8
DIJ69_RS21340	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS21345	COG1175	transmembrane transport
DIJ69_RS21350	COG1653	transport
DIJ69_RS21360	COG0515	serine threonine protein kinase
DIJ69_RS21365	COG0515	serine threonine protein kinase
DIJ69_RS21370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DIJ69_RS21385	COG2884	Cell division ATP-binding protein ftsE
DIJ69_RS21390	COG2177	Part of the ABC transporter FtsEX involved in
DIJ69_RS21395	COG0793	Belongs to the peptidase S41A family
DIJ69_RS21400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DIJ69_RS21415	COG0583	DNA-binding transcription factor activity
DIJ69_RS21435	COG2223	nitrite transmembrane transporter activity
DIJ69_RS21470	COG3973	AAA domain
DIJ69_RS21470	COG3973	AAA domain
DIJ69_RS21480	COG0776	regulation of translation
DIJ69_RS21495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIJ69_RS21500	COG1678	Uncharacterized ACR, COG1678
DIJ69_RS21515	COG1175	transmembrane transport
DIJ69_RS21520	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS21525	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIJ69_RS21585	COG2814	Major facilitator Superfamily
DIJ69_RS21595	COG3654	unkown
DIJ69_RS21610	COG3480	Lon protease (S16) C-terminal proteolytic domain
DIJ69_RS21630	COG1732	Glycine betaine
DIJ69_RS21635	COG1174	glycine betaine transport
DIJ69_RS21645	COG1174	glycine betaine transport
DIJ69_RS21655	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DIJ69_RS21665	COG0277	FAD linked oxidase domain protein
DIJ69_RS21705	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DIJ69_RS21715	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DIJ69_RS21720	COG2192	nodulation
DIJ69_RS21735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DIJ69_RS21745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DIJ69_RS21750	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DIJ69_RS21780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIJ69_RS21790	COG1335	isochorismatase
DIJ69_RS21800	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DIJ69_RS21810	COG1113	amino acid transport
DIJ69_RS21825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS21870	COG1263	PTS System
DIJ69_RS21875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIJ69_RS21880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DIJ69_RS21890	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DIJ69_RS21910	COG0477	Major facilitator Superfamily
DIJ69_RS21935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DIJ69_RS21955	COG4555	ABC transporter
DIJ69_RS21970	COG2733	membrane
DIJ69_RS21985	COG2175	clavaminate synthase activity
DIJ69_RS22000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIJ69_RS22005	COG3135	benzoate transporter
DIJ69_RS22045	COG3655	Transcriptional regulator
DIJ69_RS22120	COG0706	membrane insertase activity
DIJ69_RS22120	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
DIJ69_RS22130	COG4702	Belongs to the UPF0303 family
DIJ69_RS22135	COG0673	inositol 2-dehydrogenase activity
DIJ69_RS22140	COG1940	carbohydrate kinase activity
DIJ69_RS22150	COG2188	Transcriptional regulator
DIJ69_RS22155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIJ69_RS22235	COG3397	chitin binding
DIJ69_RS22240	COG0318	PFAM AMP-dependent synthetase and ligase
DIJ69_RS22255	COG1126	abc transporter atp-binding protein
DIJ69_RS22260	COG0765	amino acid transport
DIJ69_RS22265	COG0765	amino acid transport
DIJ69_RS22270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIJ69_RS22285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS22375	COG2985	domain, Protein
DIJ69_RS22390	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS22415	COG4977	sequence-specific DNA binding
DIJ69_RS22420	COG0589	response to stress
DIJ69_RS22425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DIJ69_RS22450	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DIJ69_RS22455	COG0076	glutamate decarboxylase activity
DIJ69_RS22460	COG2375	cellular response to nickel ion
DIJ69_RS22470	COG1733	regulation of RNA biosynthetic process
DIJ69_RS22480	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS22495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIJ69_RS22500	COG1309	transcriptional regulator
DIJ69_RS22540	COG1946	Acyl-CoA thioesterase
DIJ69_RS22560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DIJ69_RS22635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIJ69_RS22645	COG0028	Belongs to the TPP enzyme family
DIJ69_RS22675	COG1472	Belongs to the glycosyl hydrolase 3 family
DIJ69_RS22690	COG1404	Belongs to the peptidase S8 family
DIJ69_RS22720	COG0515	serine threonine protein kinase
DIJ69_RS22745	COG1609	Transcriptional regulator
DIJ69_RS22750	COG0673	inositol 2-dehydrogenase activity
DIJ69_RS22765	COG2318	DinB family
DIJ69_RS22800	COG0596	Alpha beta hydrolase
DIJ69_RS22810	COG0477	Major facilitator Superfamily
DIJ69_RS22820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DIJ69_RS22845	COG2409	Drug exporters of the RND superfamily
DIJ69_RS22860	COG2318	DinB family
DIJ69_RS22870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIJ69_RS22880	COG3718	enzyme involved in inositol metabolism
DIJ69_RS22885	COG3962	Belongs to the TPP enzyme family
DIJ69_RS22900	COG4585	Histidine kinase
DIJ69_RS22920	COG1131	(ABC) transporter
DIJ69_RS22955	COG4585	Histidine kinase
DIJ69_RS22960	COG2197	response regulator
DIJ69_RS23000	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DIJ69_RS23040	COG0629	single-stranded DNA binding
DIJ69_RS23065	COG0577	efflux transmembrane transporter activity
DIJ69_RS23065	COG1136	(ABC) transporter
DIJ69_RS23080	COG2346	COG2346, Truncated hemoglobins
DIJ69_RS23085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DIJ69_RS23115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIJ69_RS23130	COG1486	melibiose metabolic process
DIJ69_RS23135	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS23140	COG1175	transmembrane transport
DIJ69_RS23150	COG1940	carbohydrate kinase activity
DIJ69_RS23155	COG0668	transmembrane transport
DIJ69_RS23165	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIJ69_RS23165	COG3291	Pkd domain containing protein
DIJ69_RS23190	COG4266	Belongs to the allantoicase family
DIJ69_RS23215	COG2337	Toxic component of a toxin-antitoxin (TA) module
DIJ69_RS23240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DIJ69_RS23255	COG2252	PERMEase
DIJ69_RS23275	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS23285	COG0110	maltose O-acetyltransferase activity
DIJ69_RS23300	COG0640	Transcriptional regulator
DIJ69_RS23305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DIJ69_RS23315	COG0783	Belongs to the Dps family
DIJ69_RS23320	COG0584	glycerophosphoryl diester phosphodiesterase
DIJ69_RS23325	COG1113	amino acid transport
DIJ69_RS23335	COG1268	BioY protein
DIJ69_RS23345	COG1113	amino acid transport
DIJ69_RS23365	COG0475	glutathione-regulated potassium exporter activity
DIJ69_RS23375	COG3594	Acyltransferase
DIJ69_RS23395	COG0544	peptidyl-prolyl cis-trans isomerase activity
DIJ69_RS23400	COG0740	serine-type endopeptidase activity
DIJ69_RS23405	COG0740	serine-type endopeptidase activity
DIJ69_RS23410	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DIJ69_RS23420	COG0525	valine-tRNA ligase activity
DIJ69_RS23425	COG0285	dihydrofolate synthase activity
DIJ69_RS23435	COG0105	UTP biosynthetic process
DIJ69_RS23440	COG1077	Cell shape determining protein MreB Mrl
DIJ69_RS23455	COG0768	penicillin binding
DIJ69_RS23460	COG0772	Belongs to the SEDS family
DIJ69_RS23485	COG1530	ribonuclease E activity
DIJ69_RS23490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DIJ69_RS23495	COG0673	inositol 2-dehydrogenase activity
DIJ69_RS23520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DIJ69_RS23525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DIJ69_RS23530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DIJ69_RS23550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DIJ69_RS23555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DIJ69_RS23565	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DIJ69_RS23580	COG0501	Belongs to the peptidase M48B family
DIJ69_RS23585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DIJ69_RS23595	COG0799	negative regulation of ribosome biogenesis
DIJ69_RS23600	COG0588	phosphoglycerate mutase activity
DIJ69_RS23625	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DIJ69_RS23635	COG0495	leucyl-tRNA aminoacylation
DIJ69_RS23645	COG1307	EDD domain protein, DegV family
DIJ69_RS23650	COG1555	photosystem II stabilization
DIJ69_RS23655	COG1234	tRNA 3'-trailer cleavage
DIJ69_RS23680	COG0268	Binds directly to 16S ribosomal RNA
DIJ69_RS23685	COG0481	GTPase activity
DIJ69_RS23690	COG1022	Amp-dependent synthetase and ligase
DIJ69_RS23730	COG1420	regulation of RNA biosynthetic process
DIJ69_RS23735	COG0484	heat shock protein binding
DIJ69_RS23750	COG0537	adenosine 5'-monophosphoramidase activity
DIJ69_RS23755	COG1234	tRNA 3'-trailer cleavage
DIJ69_RS23760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DIJ69_RS23770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIJ69_RS23780	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DIJ69_RS23790	COG2315	Protein conserved in bacteria
DIJ69_RS23800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DIJ69_RS23815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DIJ69_RS23825	COG1381	Involved in DNA repair and RecF pathway recombination
DIJ69_RS23830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIJ69_RS23840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DIJ69_RS23845	COG1121	(ABC) transporter
DIJ69_RS23855	COG0423	glycine-tRNA ligase activity
DIJ69_RS23880	COG4221	oxidoreductase activity
DIJ69_RS23990	COG2066	Belongs to the glutaminase family
DIJ69_RS24000	COG1309	transcriptional regulator
DIJ69_RS24010	COG0477	Major facilitator Superfamily
DIJ69_RS24045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DIJ69_RS24045	COG0574	Belongs to the PEP-utilizing enzyme family
DIJ69_RS24065	COG2146	nitrite reductase [NAD(P)H] activity
DIJ69_RS24065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIJ69_RS24070	COG2146	nitrite reductase [NAD(P)H] activity
DIJ69_RS24070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIJ69_RS24115	COG2949	membrane
DIJ69_RS24125	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DIJ69_RS24135	COG0358	DNA primase activity
DIJ69_RS24155	COG1070	Carbohydrate kinase
DIJ69_RS24185	COG0477	Major facilitator Superfamily
DIJ69_RS24190	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS24195	COG1309	transcriptional regulator
DIJ69_RS24200	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DIJ69_RS24200	COG0825	malonyl-CoA metabolic process
DIJ69_RS24205	COG0318	PFAM AMP-dependent synthetase and ligase
DIJ69_RS24225	COG1522	sequence-specific DNA binding
DIJ69_RS24255	COG2130	NADP-dependent
DIJ69_RS24260	COG1764	response to oxidative stress
DIJ69_RS24270	COG1280	lysine exporter protein (LysE YggA)
DIJ69_RS24290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIJ69_RS24295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIJ69_RS24300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIJ69_RS24315	COG1741	Belongs to the pirin family
DIJ69_RS24335	COG1404	Belongs to the peptidase S8 family
DIJ69_RS24420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIJ69_RS24455	COG1929	Belongs to the glycerate kinase type-1 family
DIJ69_RS24465	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS24470	COG2205	protein histidine kinase activity
DIJ69_RS24480	COG0789	Transcriptional regulator
DIJ69_RS24485	COG0667	Aldo Keto reductase
DIJ69_RS24500	COG2197	response regulator
DIJ69_RS24505	COG4585	Histidine kinase
DIJ69_RS24520	COG1309	transcriptional regulator
DIJ69_RS24525	COG0477	Major facilitator Superfamily
DIJ69_RS24535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DIJ69_RS24585	COG1358	cellular component organization or biogenesis
DIJ69_RS24735	COG2124	cytochrome p450
DIJ69_RS24750	COG3845	ABC transporter
DIJ69_RS24830	COG1309	transcriptional regulator
DIJ69_RS24835	COG0438	transferase activity, transferring glycosyl groups
DIJ69_RS24870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS24880	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIJ69_RS24890	COG2814	Major facilitator Superfamily
DIJ69_RS24895	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS24900	COG0183	Belongs to the thiolase family
DIJ69_RS24910	COG2030	dehydratase
DIJ69_RS24920	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS24935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DIJ69_RS24955	COG0800	Aldolase
DIJ69_RS24960	COG3022	response to hydroperoxide
DIJ69_RS24990	COG2273	Hydrolase Family 16
DIJ69_RS25030	COG0384	phenazine biosynthesis protein PhzF
DIJ69_RS25040	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS25055	COG2814	Major facilitator Superfamily
DIJ69_RS25070	COG1834	amidinotransferase
DIJ69_RS25090	COG1120	ATPase activity
DIJ69_RS25095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS25160	COG1994	Peptidase M50
DIJ69_RS25180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DIJ69_RS25185	COG0477	Major facilitator Superfamily
DIJ69_RS25200	COG2814	Major facilitator Superfamily
DIJ69_RS25205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DIJ69_RS25205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIJ69_RS25210	COG2132	Multicopper oxidase
DIJ69_RS25235	COG0174	glutamine synthetase
DIJ69_RS25290	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DIJ69_RS25330	COG2814	Major facilitator Superfamily
DIJ69_RS25335	COG2890	protein-(glutamine-N5) methyltransferase activity
DIJ69_RS25345	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DIJ69_RS25355	COG1609	Transcriptional regulator
DIJ69_RS25370	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS25375	COG0366	Alpha amylase catalytic
DIJ69_RS25445	COG2197	response regulator
DIJ69_RS25450	COG4585	Histidine kinase
DIJ69_RS25455	COG2409	Drug exporters of the RND superfamily
DIJ69_RS25460	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS25485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIJ69_RS25490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIJ69_RS25510	COG2362	D-Aminopeptidase
DIJ69_RS25525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIJ69_RS25570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DIJ69_RS25575	COG0321	lipoyl(octanoyl) transferase activity
DIJ69_RS25595	COG1090	epimerase
DIJ69_RS25625	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIJ69_RS25630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIJ69_RS25635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DIJ69_RS25640	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DIJ69_RS25655	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DIJ69_RS25675	COG4106	trans-aconitate 2-methyltransferase activity
DIJ69_RS25695	COG4585	Histidine kinase
DIJ69_RS25700	COG2197	response regulator
DIJ69_RS25705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIJ69_RS25715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DIJ69_RS25735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIJ69_RS25745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DIJ69_RS25750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DIJ69_RS25760	COG1376	ErfK ybiS ycfS ynhG family protein
DIJ69_RS25770	COG1845	cytochrome c oxidase, subunit III
DIJ69_RS25775	COG2010	Cytochrome c
DIJ69_RS25780	COG0723	plastoquinol--plastocyanin reductase activity
DIJ69_RS25785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DIJ69_RS25790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DIJ69_RS25795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DIJ69_RS25860	COG0003	Pfam Anion-transporting ATPase
DIJ69_RS25870	COG1940	carbohydrate kinase activity
DIJ69_RS25900	COG2197	response regulator
DIJ69_RS25905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DIJ69_RS25920	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DIJ69_RS25930	COG2193	ferroxidase activity
DIJ69_RS25935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DIJ69_RS25940	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DIJ69_RS25945	COG2815	serine threonine protein kinase
DIJ69_RS25945	COG0515	serine threonine protein kinase
DIJ69_RS25950	COG2022	thiamine diphosphate biosynthetic process
DIJ69_RS25960	COG2022	thiamine diphosphate biosynthetic process
DIJ69_RS25960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIJ69_RS25980	COG0352	thiamine-phosphate diphosphorylase activity
DIJ69_RS26015	COG1136	(ABC) transporter
DIJ69_RS26045	COG0714	Associated with various cellular activities
DIJ69_RS26055	COG0275	rRNA processing
DIJ69_RS26065	COG0768	penicillin binding
DIJ69_RS26070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DIJ69_RS26080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DIJ69_RS26085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DIJ69_RS26095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIJ69_RS26115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DIJ69_RS26120	COG1799	cell septum assembly
DIJ69_RS26130	COG3599	regulation of cell shape
DIJ69_RS26135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DIJ69_RS26145	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DIJ69_RS26190	COG0587	DNA-directed DNA polymerase activity
DIJ69_RS26200	COG1432	Conserved Protein
DIJ69_RS26240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DIJ69_RS26245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DIJ69_RS26250	COG0131	Imidazoleglycerol-phosphate dehydratase
DIJ69_RS26255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DIJ69_RS26260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DIJ69_RS26265	COG0251	oxidation-reduction process
DIJ69_RS26270	COG0107	imidazoleglycerol-phosphate synthase activity
DIJ69_RS26285	COG2508	Transcriptional regulator
DIJ69_RS26305	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DIJ69_RS26310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DIJ69_RS26330	COG0134	indole-3-glycerol-phosphate synthase activity
DIJ69_RS26340	COG0133	tryptophan synthase activity
DIJ69_RS26345	COG0159	tryptophan synthase activity
DIJ69_RS26355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DIJ69_RS26365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DIJ69_RS26370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIJ69_RS26400	COG0069	glutamate synthase activity
DIJ69_RS26400	COG0067	glutamate synthase
DIJ69_RS26400	COG0070	glutamate synthase
DIJ69_RS26430	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS26435	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS26440	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS26445	COG1309	transcriptional regulator
DIJ69_RS26450	COG0183	Belongs to the thiolase family
DIJ69_RS26455	COG1278	Cold shock
DIJ69_RS26480	COG1024	Enoyl-CoA hydratase
DIJ69_RS26485	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS26520	COG0287	Prephenate dehydrogenase
DIJ69_RS26520	COG1605	Chorismate mutase
DIJ69_RS26555	COG0737	Belongs to the 5'-nucleotidase family
DIJ69_RS26610	COG2050	protein possibly involved in aromatic compounds catabolism
DIJ69_RS26645	COG1643	Atp-dependent helicase
DIJ69_RS26650	COG2226	methyltransferase
DIJ69_RS26675	COG0237	dephospho-CoA kinase activity
DIJ69_RS26690	COG2226	methyltransferase
DIJ69_RS26700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DIJ69_RS26720	COG0436	Aminotransferase
DIJ69_RS26740	COG2313	pseudouridylate synthase activity
DIJ69_RS26750	COG2814	Major facilitator Superfamily
DIJ69_RS26755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DIJ69_RS26760	COG0584	glycerophosphoryl diester phosphodiesterase
DIJ69_RS26770	COG0556	nucleotide-excision repair
DIJ69_RS26800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DIJ69_RS26825	COG0322	excinuclease ABC activity
DIJ69_RS26830	COG1660	Displays ATPase and GTPase activities
DIJ69_RS26835	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DIJ69_RS26840	COG1481	regulation of sporulation
DIJ69_RS26845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DIJ69_RS26850	COG0126	phosphoglycerate kinase activity
DIJ69_RS26855	COG0149	triose-phosphate isomerase activity
DIJ69_RS26860	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DIJ69_RS26895	COG0363	glucosamine-6-phosphate deaminase activity
DIJ69_RS26910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DIJ69_RS26920	COG0109	protoheme IX farnesyltransferase activity
DIJ69_RS26960	COG0719	Fe-S assembly protein
DIJ69_RS26970	COG0396	ATPase activity
DIJ69_RS26975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DIJ69_RS26980	COG0822	iron-sulfur transferase activity
DIJ69_RS26985	COG2151	metal-sulfur cluster biosynthetic enzyme
DIJ69_RS27020	COG2171	N-acyltransferase activity
DIJ69_RS27025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIJ69_RS27035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DIJ69_RS27060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIJ69_RS27065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIJ69_RS27080	COG0583	DNA-binding transcription factor activity
DIJ69_RS27095	COG0431	NADPH-dependent FMN reductase
DIJ69_RS27105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS27115	COG0768	penicillin binding
DIJ69_RS27120	COG2197	response regulator
DIJ69_RS27125	COG4585	Histidine kinase
DIJ69_RS27140	COG1414	Transcriptional regulator
DIJ69_RS27170	COG1846	Transcriptional regulator
DIJ69_RS27175	COG1902	pentaerythritol trinitrate reductase activity
DIJ69_RS27205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DIJ69_RS27230	COG1797	cobyrinic acid a,c-diamide synthase activity
DIJ69_RS27245	COG1492	cobalamin metabolic process
DIJ69_RS27250	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DIJ69_RS27265	COG0235	Class ii aldolase
DIJ69_RS27290	COG0488	(ABC) transporter
DIJ69_RS27340	COG3387	PFAM Glycoside hydrolase 15-related
DIJ69_RS27355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DIJ69_RS27355	COG1199	ATP-dependent helicase activity
DIJ69_RS27385	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIJ69_RS27390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DIJ69_RS27405	COG2261	transglycosylase associated protein
DIJ69_RS27410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DIJ69_RS27425	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS27430	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DIJ69_RS27440	COG2186	Transcriptional regulator
DIJ69_RS27460	COG3830	Belongs to the UPF0237 family
DIJ69_RS27460	COG0560	Phosphoserine phosphatase
DIJ69_RS27465	COG0842	Transport permease protein
DIJ69_RS27465	COG1131	(ABC) transporter
DIJ69_RS27465	COG1716	ATPase activity
DIJ69_RS27475	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DIJ69_RS27490	COG2197	response regulator
DIJ69_RS27505	COG1119	ATPase activity
DIJ69_RS27530	COG1881	PFAM PEBP family protein
DIJ69_RS27540	COG2094	Belongs to the DNA glycosylase MPG family
DIJ69_RS27580	COG0647	UMP catabolic process
DIJ69_RS27585	COG1120	ATPase activity
DIJ69_RS27605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DIJ69_RS27610	COG0497	DNA recombination
DIJ69_RS27625	COG0789	Transcriptional regulator
DIJ69_RS27635	COG3387	PFAM Glycoside hydrolase 15-related
DIJ69_RS27640	COG0504	CTP synthase activity
DIJ69_RS27645	COG0494	nUDIX hydrolase
DIJ69_RS27670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DIJ69_RS27675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DIJ69_RS27680	COG1187	pseudouridine synthase activity
DIJ69_RS27740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DIJ69_RS27750	COG1160	GTP binding
DIJ69_RS27765	COG0438	transferase activity, transferring glycosyl groups
DIJ69_RS27785	COG0671	phosphoesterase, PA-phosphatase related
DIJ69_RS27790	COG0477	Major facilitator Superfamily
DIJ69_RS27795	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS27800	COG1799	cell septum assembly
DIJ69_RS27810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIJ69_RS27815	COG0765	amino acid transport
DIJ69_RS27830	COG1126	abc transporter atp-binding protein
DIJ69_RS27835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIJ69_RS27840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS27845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS27915	COG4565	transcriptional regulatory protein
DIJ69_RS27935	COG0346	lactoylglutathione lyase activity
DIJ69_RS27950	COG1725	Transcriptional regulator
DIJ69_RS27960	COG2755	lipolytic protein G-D-S-L family
DIJ69_RS27970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DIJ69_RS27980	COG2188	Transcriptional regulator
DIJ69_RS27985	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DIJ69_RS27990	COG1309	transcriptional regulator
DIJ69_RS27995	COG0243	molybdopterin cofactor binding
DIJ69_RS28000	COG2851	Citrate transporter
DIJ69_RS28010	COG2318	DinB family
DIJ69_RS28045	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS28065	COG0789	Transcriptional regulator
DIJ69_RS28080	COG3876	Protein conserved in bacteria
DIJ69_RS28090	COG0318	PFAM AMP-dependent synthetase and ligase
DIJ69_RS28100	COG2234	aminopeptidase activity
DIJ69_RS28100	COG4935	Belongs to the peptidase S8 family
DIJ69_RS28105	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS28115	COG4948	Mandelate Racemase Muconate Lactonizing
DIJ69_RS28130	COG2149	membrane
DIJ69_RS28135	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DIJ69_RS28140	COG3573	Dehydrogenase
DIJ69_RS28165	COG3265	gluconokinase activity
DIJ69_RS28170	COG2186	Transcriptional regulator
DIJ69_RS28185	COG0564	pseudouridine synthase activity
DIJ69_RS28195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DIJ69_RS28225	COG0667	Aldo Keto reductase
DIJ69_RS28230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS28240	COG0598	Magnesium transport protein CorA
DIJ69_RS28260	COG0215	cysteine-tRNA ligase activity
DIJ69_RS28275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS28280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DIJ69_RS28285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DIJ69_RS28290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DIJ69_RS28295	COG1414	Transcriptional regulator
DIJ69_RS28300	COG0646	methionine synthase
DIJ69_RS28300	COG1410	methionine synthase
DIJ69_RS28305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DIJ69_RS28310	COG4166	transmembrane transport
DIJ69_RS28315	COG2197	response regulator
DIJ69_RS28325	COG1994	Peptidase M50
DIJ69_RS28325	COG0517	IMP dehydrogenase activity
DIJ69_RS28350	COG1222	aaa ATPase
DIJ69_RS28355	COG4122	O-methyltransferase activity
DIJ69_RS28370	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DIJ69_RS28375	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DIJ69_RS28390	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DIJ69_RS28395	COG0545	Peptidyl-prolyl cis-trans isomerase
DIJ69_RS28405	COG2378	regulation of single-species biofilm formation
DIJ69_RS28425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIJ69_RS28430	COG0805	protein transport
DIJ69_RS28465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DIJ69_RS28470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DIJ69_RS28515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DIJ69_RS28520	COG4175	Glycine betaine
DIJ69_RS28520	COG0517	IMP dehydrogenase activity
DIJ69_RS28565	COG1404	Belongs to the peptidase S8 family
DIJ69_RS28575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DIJ69_RS28585	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DIJ69_RS28590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DIJ69_RS28595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DIJ69_RS28600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIJ69_RS28605	COG5002	protein histidine kinase activity
DIJ69_RS28610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DIJ69_RS28615	COG0072	phenylalanine-tRNA ligase activity
DIJ69_RS28615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIJ69_RS28625	COG0494	nUDIX hydrolase
DIJ69_RS28640	COG1649	PFAM Uncharacterised BCR, COG1649
DIJ69_RS28650	COG0697	spore germination
DIJ69_RS28665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIJ69_RS28715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DIJ69_RS28720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DIJ69_RS28725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DIJ69_RS28730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIJ69_RS28735	COG1438	arginine binding
DIJ69_RS28750	COG0137	argininosuccinate synthase activity
DIJ69_RS28755	COG0165	Argininosuccinate lyase
DIJ69_RS28775	COG0477	Major facilitator Superfamily
DIJ69_RS28815	COG2011	ABC-type metal ion transport system permease component
DIJ69_RS28820	COG1464	Belongs to the NlpA lipoprotein family
DIJ69_RS28835	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DIJ69_RS28840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DIJ69_RS28840	COG1648	precorrin-2 dehydrogenase activity
DIJ69_RS28895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DIJ69_RS28905	COG0454	-acetyltransferase
DIJ69_RS28905	COG0456	acetyltransferase
DIJ69_RS28950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DIJ69_RS28965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DIJ69_RS28990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DIJ69_RS28995	COG1560	Kdo2-lipid A biosynthetic process
DIJ69_RS29000	COG0438	transferase activity, transferring glycosyl groups
DIJ69_RS29010	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DIJ69_RS29015	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DIJ69_RS29020	COG0217	transcriptional regulatory protein
DIJ69_RS29025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DIJ69_RS29030	COG0632	four-way junction helicase activity
DIJ69_RS29035	COG2255	four-way junction helicase activity
DIJ69_RS29045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DIJ69_RS29050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DIJ69_RS29055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DIJ69_RS29060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DIJ69_RS29065	COG1196	nuclear chromosome segregation
DIJ69_RS29080	COG0124	histidyl-tRNA synthetase
DIJ69_RS29100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DIJ69_RS29120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DIJ69_RS29125	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DIJ69_RS29140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DIJ69_RS29145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DIJ69_RS29150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DIJ69_RS29155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DIJ69_RS29165	COG0006	proline dipeptidase activity
DIJ69_RS29170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DIJ69_RS29175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DIJ69_RS29185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DIJ69_RS29190	COG0540	Belongs to the ATCase OTCase family
DIJ69_RS29195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DIJ69_RS29205	COG0505	Belongs to the CarA family
DIJ69_RS29210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DIJ69_RS29215	COG0167	dihydroorotate dehydrogenase activity
DIJ69_RS29220	COG0284	orotidine-5'-phosphate decarboxylase activity
DIJ69_RS29235	COG1758	RNA polymerase activity
DIJ69_RS29245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DIJ69_RS29250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DIJ69_RS29260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DIJ69_RS29270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DIJ69_RS29275	COG2390	Transcriptional regulator
DIJ69_RS29290	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS29300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIJ69_RS29340	COG2233	PERMEase
DIJ69_RS29345	COG0738	Major facilitator superfamily
DIJ69_RS29350	COG1940	carbohydrate kinase activity
DIJ69_RS29355	COG0702	epimerase
DIJ69_RS29375	COG3201	nicotinamide mononucleotide transporter
DIJ69_RS29380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DIJ69_RS29380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DIJ69_RS29385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DIJ69_RS29390	COG0140	phosphoribosyl-ATP diphosphatase activity
DIJ69_RS29395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DIJ69_RS29445	COG2318	DinB family
DIJ69_RS29460	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS29485	COG1216	Glycosyl transferase, family 2
DIJ69_RS29500	COG2270	Major facilitator Superfamily
DIJ69_RS29510	COG2364	Membrane
DIJ69_RS29580	COG2018	Roadblock/LC7 domain
DIJ69_RS29595	COG2732	(Barnase) inhibitor
DIJ69_RS29615	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DIJ69_RS29630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIJ69_RS29640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DIJ69_RS29675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DIJ69_RS29695	COG1716	ATPase activity
DIJ69_RS29725	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DIJ69_RS29725	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DIJ69_RS29815	COG1695	Transcriptional regulator
DIJ69_RS29855	COG0697	spore germination
DIJ69_RS29860	COG0583	DNA-binding transcription factor activity
DIJ69_RS29925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DIJ69_RS29940	COG2318	DinB family
DIJ69_RS29950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DIJ69_RS29990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DIJ69_RS29995	COG2226	methyltransferase
DIJ69_RS30000	COG0243	molybdopterin cofactor binding
DIJ69_RS30015	COG1968	undecaprenyl-diphosphatase activity
DIJ69_RS30035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DIJ69_RS30075	COG2746	aminoglycoside 3-N-acetyltransferase activity
DIJ69_RS30080	COG1832	CoA-binding protein
DIJ69_RS30085	COG1739	Uncharacterized protein family UPF0029
DIJ69_RS30090	COG0420	3'-5' exonuclease activity
DIJ69_RS30095	COG0419	ATPase involved in DNA repair
DIJ69_RS30100	COG1522	sequence-specific DNA binding
DIJ69_RS30125	COG0626	cystathionine gamma-synthase activity
DIJ69_RS30165	COG1595	DNA-templated transcription, initiation
DIJ69_RS30170	COG2188	Transcriptional regulator
DIJ69_RS30175	COG1940	carbohydrate kinase activity
DIJ69_RS30185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DIJ69_RS30215	COG2226	methyltransferase
DIJ69_RS30220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DIJ69_RS30225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DIJ69_RS30230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DIJ69_RS30235	COG0156	8-amino-7-oxononanoate synthase activity
DIJ69_RS30255	COG0583	DNA-binding transcription factor activity
DIJ69_RS30260	COG1280	lysine exporter protein (LysE YggA)
DIJ69_RS30275	COG0740	serine-type endopeptidase activity
DIJ69_RS30290	COG1309	transcriptional regulator
DIJ69_RS30295	COG0831	urea catabolic process
DIJ69_RS30300	COG0832	Belongs to the urease beta subunit family
DIJ69_RS30305	COG0804	urea catabolic process
DIJ69_RS30315	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DIJ69_RS30320	COG0829	nickel cation binding
DIJ69_RS30335	COG0204	Acyl-transferase
DIJ69_RS30345	COG0205	6-phosphofructokinase activity
DIJ69_RS30350	COG3442	glutamine amidotransferase
DIJ69_RS30360	COG0242	peptide deformylase activity
DIJ69_RS30370	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS30375	COG0386	Belongs to the glutathione peroxidase family
DIJ69_RS30405	COG1946	Acyl-CoA thioesterase
DIJ69_RS30425	COG1252	NADH dehydrogenase
DIJ69_RS30440	COG1132	(ABC) transporter
DIJ69_RS30455	COG0277	FAD linked oxidase domain protein
DIJ69_RS30460	COG1846	Transcriptional regulator
DIJ69_RS30475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DIJ69_RS30485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS30495	COG1116	anion transmembrane transporter activity
DIJ69_RS30500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIJ69_RS30520	COG0596	Alpha beta hydrolase
DIJ69_RS30525	COG1309	transcriptional regulator
DIJ69_RS30550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIJ69_RS30575	COG1959	2 iron, 2 sulfur cluster binding
DIJ69_RS30620	COG1131	(ABC) transporter
DIJ69_RS30675	COG1126	abc transporter atp-binding protein
DIJ69_RS30705	COG1191	sigma factor activity
DIJ69_RS30725	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DIJ69_RS30745	COG0142	geranyltranstransferase activity
DIJ69_RS30795	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS30810	COG1335	isochorismatase
DIJ69_RS30845	COG0640	Transcriptional regulator
DIJ69_RS30850	COG1247	-acetyltransferase
DIJ69_RS30860	COG0798	PFAM Bile acid sodium symporter
DIJ69_RS30870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIJ69_RS30890	COG2197	response regulator
DIJ69_RS30955	COG1309	transcriptional regulator
DIJ69_RS30970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DIJ69_RS30990	COG0385	Bile acid
DIJ69_RS30995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIJ69_RS31010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DIJ69_RS31035	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DIJ69_RS31050	COG1891	lyase activity
DIJ69_RS31060	COG2160	L-arabinose isomerase activity
DIJ69_RS31070	COG1609	Transcriptional regulator
DIJ69_RS31085	COG1129	ABC transporter
DIJ69_RS31090	COG4214	carbohydrate transport
DIJ69_RS31130	COG4592	Periplasmic binding protein
DIJ69_RS31140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS31145	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS31155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DIJ69_RS31175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DIJ69_RS31190	COG1174	glycine betaine transport
DIJ69_RS31200	COG2986	histidine ammonia-lyase
DIJ69_RS31215	COG2080	2 iron, 2 sulfur cluster binding
DIJ69_RS31220	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DIJ69_RS31225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DIJ69_RS31250	COG2890	protein-(glutamine-N5) methyltransferase activity
DIJ69_RS31270	COG1191	sigma factor activity
DIJ69_RS31330	COG0542	response to heat
DIJ69_RS31350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DIJ69_RS31350	COG0515	serine threonine protein kinase
DIJ69_RS31365	COG0402	S-adenosylhomocysteine deaminase activity
DIJ69_RS31370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DIJ69_RS31375	COG1802	Transcriptional regulator
DIJ69_RS31385	COG2835	tetraacyldisaccharide 4'-kinase activity
DIJ69_RS31405	COG4981	capsule polysaccharide biosynthetic process
DIJ69_RS31435	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS31440	COG0174	glutamine synthetase
DIJ69_RS31450	COG0531	amino acid
DIJ69_RS31455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DIJ69_RS31490	COG1253	flavin adenine dinucleotide binding
DIJ69_RS31525	COG0667	Aldo Keto reductase
DIJ69_RS31530	COG2815	serine threonine protein kinase
DIJ69_RS31530	COG0515	serine threonine protein kinase
DIJ69_RS31550	COG2706	6-phosphogluconolactonase activity
DIJ69_RS31565	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DIJ69_RS31610	COG0671	phosphoesterase, PA-phosphatase related
DIJ69_RS31630	COG0584	glycerophosphoryl diester phosphodiesterase
DIJ69_RS31675	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DIJ69_RS31705	COG1940	carbohydrate kinase activity
DIJ69_RS31715	COG1660	Displays ATPase and GTPase activities
DIJ69_RS31730	COG0445	tRNA wobble uridine modification
DIJ69_RS31760	COG2223	nitrite transmembrane transporter activity
DIJ69_RS31765	COG1940	carbohydrate kinase activity
DIJ69_RS31795	COG0702	epimerase
DIJ69_RS31810	COG1349	DNA-binding transcription factor activity
DIJ69_RS31820	COG0464	growth
DIJ69_RS31840	COG1215	transferase activity, transferring glycosyl groups
DIJ69_RS31900	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS31995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DIJ69_RS32005	COG1132	(ABC) transporter
DIJ69_RS32010	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS32015	COG0328	RNA-DNA hybrid ribonuclease activity
DIJ69_RS32060	COG0515	serine threonine protein kinase
DIJ69_RS32060	COG2815	serine threonine protein kinase
DIJ69_RS32070	COG1716	ATPase activity
DIJ69_RS32070	COG0842	Transport permease protein
DIJ69_RS32070	COG1131	(ABC) transporter
DIJ69_RS32100	COG1879	ABC-type sugar transport system periplasmic component
DIJ69_RS32105	COG1129	ABC transporter
DIJ69_RS32115	COG1172	Belongs to the binding-protein-dependent transport system permease family
DIJ69_RS32120	COG1609	Transcriptional regulator
DIJ69_RS32130	COG0366	Alpha amylase catalytic
DIJ69_RS32130	COG1874	Beta-galactosidase
DIJ69_RS32155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS32160	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS32165	COG1120	ATPase activity
DIJ69_RS32170	COG2837	iron assimilation
DIJ69_RS32205	COG1959	2 iron, 2 sulfur cluster binding
DIJ69_RS32205	COG1295	ribonuclease BN
DIJ69_RS32250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIJ69_RS32280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DIJ69_RS32285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DIJ69_RS32300	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIJ69_RS32305	COG3246	L-lysine catabolic process to acetate
DIJ69_RS32310	COG1309	transcriptional regulator
DIJ69_RS32315	COG1191	sigma factor activity
DIJ69_RS32345	COG0488	(ABC) transporter
DIJ69_RS32360	COG1461	Dihydroxyacetone kinase
DIJ69_RS32365	COG2376	Dihydroxyacetone kinase
DIJ69_RS32385	COG0596	Alpha beta hydrolase
DIJ69_RS32415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIJ69_RS32430	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS32495	COG0587	DNA-directed DNA polymerase activity
DIJ69_RS32500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIJ69_RS32550	COG0745	RESPONSE REGULATOR receiver
DIJ69_RS32555	COG5002	protein histidine kinase activity
DIJ69_RS32570	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DIJ69_RS32575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS32580	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS32585	COG1120	ATPase activity
DIJ69_RS32590	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DIJ69_RS32595	COG1132	(ABC) transporter
DIJ69_RS32605	COG1132	(ABC) transporter
DIJ69_RS32610	COG2382	esterase
DIJ69_RS32620	COG0148	phosphopyruvate hydratase activity
DIJ69_RS32635	COG1470	cell adhesion involved in biofilm formation
DIJ69_RS32675	COG1535	isochorismatase
DIJ69_RS32675	COG3433	isochorismatase activity
DIJ69_RS32680	COG1535	isochorismatase
DIJ69_RS32680	COG3433	isochorismatase activity
DIJ69_RS32685	COG1021	2,3-dihydroxybenzoate-AMP ligase
DIJ69_RS32690	COG1169	isochorismate synthase
DIJ69_RS32695	COG1028	Short-chain dehydrogenase reductase Sdr
DIJ69_RS32700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIJ69_RS32705	COG2382	esterase
DIJ69_RS32710	COG0477	Major facilitator Superfamily
DIJ69_RS32720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIJ69_RS32730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIJ69_RS32735	COG1120	ATPase activity
DIJ69_RS32760	COG2365	Tyrosine phosphatase family
DIJ69_RS32815	COG2080	2 iron, 2 sulfur cluster binding
DIJ69_RS32820	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DIJ69_RS32825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DIJ69_RS32835	COG1012	belongs to the aldehyde dehydrogenase family
DIJ69_RS32840	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DIJ69_RS32845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIJ69_RS32865	COG2066	Belongs to the glutaminase family
DIJ69_RS32865	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DIJ69_RS32870	COG2356	endonuclease I
DIJ69_RS32885	COG2813	Specifically methylates the guanine in position
DIJ69_RS32890	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS32910	COG0515	serine threonine protein kinase
DIJ69_RS32930	COG2070	2-Nitropropane dioxygenase
DIJ69_RS32940	COG2366	antibiotic biosynthetic process
DIJ69_RS32960	COG0765	amino acid transport
DIJ69_RS32965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIJ69_RS32985	COG1024	Enoyl-CoA hydratase
DIJ69_RS33015	COG1309	transcriptional regulator
DIJ69_RS33030	COG0300	oxidoreductase activity
DIJ69_RS33070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DIJ69_RS33075	COG0254	rRNA binding
DIJ69_RS33105	COG2318	DinB family
DIJ69_RS33160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIJ69_RS33170	COG1105	Belongs to the carbohydrate kinase PfkB family
DIJ69_RS33175	COG1349	DNA-binding transcription factor activity
DIJ69_RS33190	COG0596	Alpha beta hydrolase
DIJ69_RS33195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIJ69_RS33235	COG1175	transmembrane transport
DIJ69_RS33240	COG0395	ABC-type sugar transport system, permease component
DIJ69_RS33245	COG0366	Alpha amylase catalytic
DIJ69_RS33255	COG2318	DinB family
DIJ69_RS33270	COG0642	Histidine kinase
DIJ69_RS33285	COG0583	DNA-binding transcription factor activity
DIJ69_RS33315	COG0702	epimerase
DIJ69_RS33325	COG2226	methyltransferase
DIJ69_RS33335	COG1064	alcohol dehydrogenase
DIJ69_RS33345	COG0277	FAD linked oxidase domain protein
DIJ69_RS33405	COG1764	response to oxidative stress
DIJ69_RS33410	COG1846	Transcriptional regulator
DIJ69_RS33420	COG0477	Major facilitator Superfamily
DIJ69_RS33440	COG0477	Major facilitator Superfamily
DIJ69_RS33455	COG5297	Belongs to the glycosyl hydrolase family 6
DIJ69_RS33470	COG4941	Belongs to the sigma-70 factor family
DIJ69_RS33475	COG3795	YCII-related domain
DIJ69_RS33535	COG2770	Histidine kinase
DIJ69_RS33535	COG2208	phosphoserine phosphatase activity
DIJ69_RS33555	COG0142	geranyltranstransferase activity
DIJ69_RS33575	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DIJ69_RS33605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DIJ69_RS33620	COG0300	oxidoreductase activity
DIJ69_RS33650	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DIJ69_RS33655	COG3457	Alanine racemase
DIJ69_RS33660	COG0626	cystathionine gamma-synthase activity
DIJ69_RS33665	COG1735	metal-dependent hydrolase with the TIM-barrel fold
DIJ69_RS33685	COG2188	Transcriptional regulator
DIJ69_RS33695	COG2197	response regulator
DIJ69_RS33760	COG2382	esterase
DIJ69_RS33760	COG3507	Belongs to the glycosyl hydrolase 43 family
DIJ69_RS33760	COG3693	PFAM glycoside hydrolase, family 10
DIJ69_RS33770	COG0477	Major facilitator Superfamily
DIJ69_RS33795	COG3507	Belongs to the glycosyl hydrolase 43 family
DIJ69_RS33795	COG3693	PFAM glycoside hydrolase, family 10
DIJ69_RS33795	COG2382	esterase
DIJ69_RS33815	COG1192	Involved in chromosome partitioning
DIJ69_RS33940	COG0604	alcohol dehydrogenase
DIJ69_RS33940	COG3321	synthase
DIJ69_RS34020	COG1960	acyl-CoA dehydrogenase activity
DIJ69_RS34035	COG2409	Drug exporters of the RND superfamily
DIJ69_RS34095	COG0477	Major facilitator Superfamily
DIJ69_RS34110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIJ69_RS34145	COG0596	Alpha beta hydrolase
DIJ69_RS34180	COG0475	glutathione-regulated potassium exporter activity
DIJ69_RS34185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DIJ69_RS34380	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DIJ69_RS34405	COG1191	sigma factor activity