locus-tag	class	description
FJ654_RS00040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJ654_RS00060	COG0673	inositol 2-dehydrogenase activity
FJ654_RS00065	COG0673	inositol 2-dehydrogenase activity
FJ654_RS00070	COG1609	Transcriptional regulator
FJ654_RS00075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS00085	COG3718	enzyme involved in inositol metabolism
FJ654_RS00105	COG2814	Major facilitator Superfamily
FJ654_RS00110	COG0673	inositol 2-dehydrogenase activity
FJ654_RS00115	COG1082	Xylose isomerase domain protein TIM barrel
FJ654_RS00120	COG3408	Glycogen debranching enzyme
FJ654_RS00120	COG3119	arylsulfatase activity
FJ654_RS00135	COG3250	beta-galactosidase activity
FJ654_RS00155	COG0444	Belongs to the ABC transporter superfamily
FJ654_RS00160	COG0601	transmembrane transport
FJ654_RS00185	COG2723	6-phospho-beta-galactosidase activity
FJ654_RS00190	COG2814	Major facilitator Superfamily
FJ654_RS00195	COG3250	beta-galactosidase activity
FJ654_RS00215	COG2423	ornithine cyclodeaminase activity
FJ654_RS00235	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS00255	COG0183	Belongs to the thiolase family
FJ654_RS00280	COG3246	L-lysine catabolic process to acetate
FJ654_RS00285	COG1309	transcriptional regulator
FJ654_RS00290	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS00300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJ654_RS00315	COG1024	Enoyl-CoA hydratase
FJ654_RS00330	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS00385	COG1309	transcriptional regulator
FJ654_RS00390	COG2814	Major facilitator Superfamily
FJ654_RS00410	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS00415	COG3958	Transketolase
FJ654_RS00420	COG3959	Transketolase, thiamine diphosphate binding domain
FJ654_RS00615	COG1510	regulation of RNA biosynthetic process
FJ654_RS00625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FJ654_RS00635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FJ654_RS00650	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FJ654_RS00655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FJ654_RS00680	COG0475	glutathione-regulated potassium exporter activity
FJ654_RS00685	COG2808	Putative FMN-binding domain
FJ654_RS00700	COG1510	regulation of RNA biosynthetic process
FJ654_RS00715	COG0183	Belongs to the thiolase family
FJ654_RS00735	COG1834	amidinotransferase
FJ654_RS00750	COG2124	cytochrome p450
FJ654_RS00900	COG2318	DinB family
FJ654_RS00910	COG0604	alcohol dehydrogenase
FJ654_RS00930	COG0800	Aldolase
FJ654_RS00940	COG4948	Mandelate Racemase Muconate Lactonizing
FJ654_RS00945	COG2186	Transcriptional regulator
FJ654_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS00960	COG0395	ABC-type sugar transport system, permease component
FJ654_RS00960	COG0395	ABC-type sugar transport system, permease component
FJ654_RS00965	COG1175	transmembrane transport
FJ654_RS00975	COG3345	alpha-galactosidase
FJ654_RS00995	COG2814	Major facilitator Superfamily
FJ654_RS01005	COG0583	DNA-binding transcription factor activity
FJ654_RS01020	COG2267	carboxylic ester hydrolase activity
FJ654_RS01055	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS01060	COG2409	Drug exporters of the RND superfamily
FJ654_RS01065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FJ654_RS01070	COG0477	Major facilitator Superfamily
FJ654_RS01075	COG1733	regulation of RNA biosynthetic process
FJ654_RS01080	COG0583	DNA-binding transcription factor activity
FJ654_RS01090	COG2814	Major facilitator Superfamily
FJ654_RS01100	COG3903	Transcriptional regulator
FJ654_RS01100	COG3629	intracellular signal transduction
FJ654_RS01120	COG2816	NAD+ diphosphatase activity
FJ654_RS01195	COG2814	Major facilitator Superfamily
FJ654_RS01205	COG2409	Drug exporters of the RND superfamily
FJ654_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS01250	COG0659	secondary active sulfate transmembrane transporter activity
FJ654_RS01295	COG0456	acetyltransferase
FJ654_RS01295	COG0454	-acetyltransferase
FJ654_RS01345	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FJ654_RS01355	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS01360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FJ654_RS01365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FJ654_RS01370	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS01385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS01400	COG0277	FAD linked oxidase domain protein
FJ654_RS01430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FJ654_RS01445	COG0477	Major facilitator Superfamily
FJ654_RS01455	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS01465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS01480	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS01490	COG0583	DNA-binding transcription factor activity
FJ654_RS01505	COG3629	intracellular signal transduction
FJ654_RS01505	COG3903	Transcriptional regulator
FJ654_RS01565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJ654_RS01605	COG2197	response regulator
FJ654_RS01625	COG0583	DNA-binding transcription factor activity
FJ654_RS01645	COG1309	transcriptional regulator
FJ654_RS01655	COG0739	heme binding
FJ654_RS01685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJ654_RS01710	COG2072	flavoprotein involved in K transport
FJ654_RS01740	COG0254	rRNA binding
FJ654_RS01745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FJ654_RS01755	COG4989	oxidoreductase activity
FJ654_RS01800	COG0516	GMP reductase activity
FJ654_RS01800	COG0517	IMP dehydrogenase activity
FJ654_RS01830	COG2326	polyphosphate kinase activity
FJ654_RS01880	COG3693	PFAM glycoside hydrolase, family 10
FJ654_RS01895	COG0300	oxidoreductase activity
FJ654_RS01930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FJ654_RS01935	COG3851	Histidine kinase
FJ654_RS01940	COG2197	response regulator
FJ654_RS01950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJ654_RS01960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FJ654_RS01975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJ654_RS02010	COG0673	inositol 2-dehydrogenase activity
FJ654_RS02020	COG1172	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS02025	COG1129	ABC transporter
FJ654_RS02030	COG1940	carbohydrate kinase activity
FJ654_RS02035	COG0443	Heat shock 70 kDa protein
FJ654_RS02045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FJ654_RS02060	COG2208	phosphoserine phosphatase activity
FJ654_RS02060	COG2770	Histidine kinase
FJ654_RS02115	COG2197	response regulator
FJ654_RS02130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJ654_RS02180	COG1397	ADP-ribosylglycohydrolase
FJ654_RS02190	COG5520	Belongs to the glycosyl hydrolase 30 family
FJ654_RS02240	COG3655	Transcriptional regulator
FJ654_RS02250	COG2318	DinB family
FJ654_RS02285	COG2186	Transcriptional regulator
FJ654_RS02295	COG1175	transmembrane transport
FJ654_RS02300	COG0395	ABC-type sugar transport system, permease component
FJ654_RS02320	COG1063	alcohol dehydrogenase
FJ654_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS02330	COG0800	Aldolase
FJ654_RS02355	COG1606	tRNA processing
FJ654_RS02360	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FJ654_RS02365	COG1691	(AIR) carboxylase
FJ654_RS02370	COG3875	lactate racemase activity
FJ654_RS02385	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS02395	COG2186	Transcriptional regulator
FJ654_RS02400	COG4948	Mandelate Racemase Muconate Lactonizing
FJ654_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS02415	COG1129	ABC transporter
FJ654_RS02420	COG1172	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS02425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FJ654_RS02435	COG0667	Aldo Keto reductase
FJ654_RS02450	COG3507	Belongs to the glycosyl hydrolase 43 family
FJ654_RS02460	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS02465	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS02470	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS02475	COG1309	transcriptional regulator
FJ654_RS02480	COG0183	Belongs to the thiolase family
FJ654_RS02500	COG1024	Enoyl-CoA hydratase
FJ654_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS02520	COG2261	transglycosylase associated protein
FJ654_RS02535	COG1191	sigma factor activity
FJ654_RS02550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FJ654_RS02565	COG3226	Transcriptional regulator
FJ654_RS02570	COG0738	Major facilitator superfamily
FJ654_RS02575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FJ654_RS02585	COG1366	Belongs to the anti-sigma-factor antagonist family
FJ654_RS02590	COG5002	protein histidine kinase activity
FJ654_RS02590	COG0784	Response regulator, receiver
FJ654_RS02590	COG2205	protein histidine kinase activity
FJ654_RS02605	COG0514	ATP-dependent DNA helicase (RecQ)
FJ654_RS02610	COG1982	Orn Lys Arg decarboxylase major
FJ654_RS02620	COG0367	asparagine synthase
FJ654_RS02625	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FJ654_RS02625	COG2308	Evidence 4 Homologs of previously reported genes of
FJ654_RS02680	COG0753	catalase activity
FJ654_RS02720	COG0784	Response regulator, receiver
FJ654_RS02725	COG4251	negative regulation of phosphorylation
FJ654_RS02745	COG3903	Transcriptional regulator
FJ654_RS02745	COG3629	intracellular signal transduction
FJ654_RS02845	COG2124	cytochrome p450
FJ654_RS02850	COG2353	YceI-like domain
FJ654_RS02855	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJ654_RS02865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FJ654_RS02870	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS02875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FJ654_RS02875	COG3321	synthase
FJ654_RS02905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FJ654_RS02915	COG1136	(ABC) transporter
FJ654_RS02920	COG4585	Histidine kinase
FJ654_RS02925	COG2197	response regulator
FJ654_RS02950	COG0009	L-threonylcarbamoyladenylate synthase
FJ654_RS02980	COG1131	(ABC) transporter
FJ654_RS02985	COG0842	Transport permease protein
FJ654_RS02995	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS03000	COG5001	Diguanylate cyclase
FJ654_RS03000	COG3300	MHYT domain
FJ654_RS03025	COG1175	transmembrane transport
FJ654_RS03030	COG0395	ABC-type sugar transport system, permease component
FJ654_RS03040	COG1609	Transcriptional regulator
FJ654_RS03045	COG0656	L-ascorbic acid biosynthetic process
FJ654_RS03085	COG2197	response regulator
FJ654_RS03095	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS03120	COG2814	Major facilitator Superfamily
FJ654_RS03125	COG0181	hydroxymethylbilane synthase activity
FJ654_RS03135	COG0842	Transport permease protein
FJ654_RS03150	COG1191	sigma factor activity
FJ654_RS03180	COG0366	Alpha amylase catalytic
FJ654_RS03190	COG3281	Trehalose synthase
FJ654_RS03195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FJ654_RS03200	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FJ654_RS03225	COG1252	NADH dehydrogenase
FJ654_RS03270	COG1982	Orn Lys Arg decarboxylase major
FJ654_RS03280	COG0477	Major facilitator Superfamily
FJ654_RS03315	COG5002	protein histidine kinase activity
FJ654_RS03320	COG0745	RESPONSE REGULATOR receiver
FJ654_RS03335	COG3189	MarR family transcriptional regulator
FJ654_RS03355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FJ654_RS03375	COG0492	ferredoxin-NADP+ reductase activity
FJ654_RS03380	COG3852	Histidine kinase
FJ654_RS03390	COG1672	PFAM Archaeal ATPase
FJ654_RS03390	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FJ654_RS03405	COG3345	alpha-galactosidase
FJ654_RS03410	COG1940	carbohydrate kinase activity
FJ654_RS03410	COG1846	Transcriptional regulator
FJ654_RS03420	COG2340	Cysteine-rich secretory protein family
FJ654_RS03440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FJ654_RS03445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJ654_RS03445	COG0515	serine threonine protein kinase
FJ654_RS03455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS03470	COG3647	Membrane
FJ654_RS03480	COG0667	Aldo Keto reductase
FJ654_RS03495	COG0477	Major facilitator Superfamily
FJ654_RS03520	COG0328	RNA-DNA hybrid ribonuclease activity
FJ654_RS03530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FJ654_RS03540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FJ654_RS03545	COG0745	RESPONSE REGULATOR receiver
FJ654_RS03565	COG0596	Alpha beta hydrolase
FJ654_RS03570	COG0740	serine-type endopeptidase activity
FJ654_RS03575	COG0740	serine-type endopeptidase activity
FJ654_RS03580	COG1396	sequence-specific DNA binding
FJ654_RS03585	COG1191	sigma factor activity
FJ654_RS03615	COG1716	ATPase activity
FJ654_RS03615	COG1131	(ABC) transporter
FJ654_RS03615	COG0842	Transport permease protein
FJ654_RS03630	COG0667	Aldo Keto reductase
FJ654_RS03635	COG0583	DNA-binding transcription factor activity
FJ654_RS03650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FJ654_RS03655	COG0346	lactoylglutathione lyase activity
FJ654_RS03660	COG0412	Dienelactone hydrolase
FJ654_RS03665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FJ654_RS03680	COG0667	Aldo Keto reductase
FJ654_RS03685	COG1082	Xylose isomerase domain protein TIM barrel
FJ654_RS03685	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FJ654_RS03690	COG1414	Transcriptional regulator
FJ654_RS03695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FJ654_RS03710	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS03715	COG4941	Belongs to the sigma-70 factor family
FJ654_RS03740	COG0431	NADPH-dependent FMN reductase
FJ654_RS03770	COG2409	Drug exporters of the RND superfamily
FJ654_RS03775	COG1846	Transcriptional regulator
FJ654_RS03780	COG0702	epimerase
FJ654_RS03825	COG2814	Major facilitator Superfamily
FJ654_RS03880	COG2319	Wd-40 repeat
FJ654_RS03880	COG4249	Peptidase C14 caspase catalytic subunit p20
FJ654_RS03915	COG1024	Enoyl-CoA hydratase
FJ654_RS03930	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS03935	COG2366	antibiotic biosynthetic process
FJ654_RS03945	COG2070	2-Nitropropane dioxygenase
FJ654_RS03955	COG0515	serine threonine protein kinase
FJ654_RS03965	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS03980	COG3387	PFAM Glycoside hydrolase 15-related
FJ654_RS04000	COG2376	Dihydroxyacetone kinase
FJ654_RS04005	COG1461	Dihydroxyacetone kinase
FJ654_RS04010	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FJ654_RS04035	COG0446	pyridine nucleotide-disulphide oxidoreductase
FJ654_RS04035	COG1902	pentaerythritol trinitrate reductase activity
FJ654_RS04050	COG0475	glutathione-regulated potassium exporter activity
FJ654_RS04075	COG2890	protein-(glutamine-N5) methyltransferase activity
FJ654_RS04095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FJ654_RS04110	COG3458	cephalosporin-C deacetylase activity
FJ654_RS04115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJ654_RS04125	COG2226	methyltransferase
FJ654_RS04130	COG1695	Transcriptional regulator
FJ654_RS04140	COG4941	Belongs to the sigma-70 factor family
FJ654_RS04150	COG3795	YCII-related domain
FJ654_RS04155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FJ654_RS04160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FJ654_RS04165	COG1686	Belongs to the peptidase S11 family
FJ654_RS04180	COG2066	Belongs to the glutaminase family
FJ654_RS04195	COG1113	amino acid transport
FJ654_RS04200	COG2186	Transcriptional regulator
FJ654_RS04205	COG1968	undecaprenyl-diphosphatase activity
FJ654_RS04210	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FJ654_RS04215	COG1993	acr, cog1993
FJ654_RS04220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FJ654_RS04285	COG0667	Aldo Keto reductase
FJ654_RS04300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJ654_RS04305	COG1316	TRANSCRIPTIONal
FJ654_RS04310	COG0640	Transcriptional regulator
FJ654_RS04330	COG1653	transport
FJ654_RS04335	COG1175	transmembrane transport
FJ654_RS04340	COG0395	ABC-type sugar transport system, permease component
FJ654_RS04355	COG1090	epimerase
FJ654_RS04365	COG2814	Major facilitator Superfamily
FJ654_RS04375	COG2723	6-phospho-beta-galactosidase activity
FJ654_RS04380	COG0395	ABC-type sugar transport system, permease component
FJ654_RS04385	COG1175	transmembrane transport
FJ654_RS04390	COG2182	Extracellular solute-binding protein
FJ654_RS04420	COG1408	metallophosphoesterase
FJ654_RS04425	COG2376	Dihydroxyacetone kinase
FJ654_RS04430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FJ654_RS04435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FJ654_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS04505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FJ654_RS04510	COG0463	Glycosyl transferase, family 2
FJ654_RS04550	COG1349	DNA-binding transcription factor activity
FJ654_RS04630	COG1940	carbohydrate kinase activity
FJ654_RS04640	COG2813	Specifically methylates the guanine in position
FJ654_RS04650	COG0191	fructose-bisphosphate aldolase activity
FJ654_RS04655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJ654_RS04660	COG1349	DNA-binding transcription factor activity
FJ654_RS04665	COG3387	PFAM Glycoside hydrolase 15-related
FJ654_RS04695	COG0673	inositol 2-dehydrogenase activity
FJ654_RS04730	COG1609	Transcriptional regulator
FJ654_RS04740	COG2814	Major facilitator Superfamily
FJ654_RS04750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FJ654_RS04775	COG1703	isobutyryl-CoA mutase activity
FJ654_RS04775	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS04775	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS04780	COG2207	Transcriptional regulator
FJ654_RS04785	COG0667	Aldo Keto reductase
FJ654_RS04790	COG2409	Drug exporters of the RND superfamily
FJ654_RS04810	COG1653	transport
FJ654_RS04825	COG0515	serine threonine protein kinase
FJ654_RS04825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJ654_RS04865	COG2223	nitrite transmembrane transporter activity
FJ654_RS04870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FJ654_RS04925	COG2197	response regulator
FJ654_RS04930	COG4585	Histidine kinase
FJ654_RS04945	COG0445	tRNA wobble uridine modification
FJ654_RS04960	COG4608	Belongs to the ABC transporter superfamily
FJ654_RS04970	COG0601	transmembrane transport
FJ654_RS04975	COG0747	negative chemotaxis
FJ654_RS04980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJ654_RS04985	COG1660	Displays ATPase and GTPase activities
FJ654_RS05010	COG0515	serine threonine protein kinase
FJ654_RS05025	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FJ654_RS05050	COG0204	Acyl-transferase
FJ654_RS05065	COG0456	acetyltransferase
FJ654_RS05085	COG0584	glycerophosphoryl diester phosphodiesterase
FJ654_RS05135	COG1309	transcriptional regulator
FJ654_RS05165	COG0640	Transcriptional regulator
FJ654_RS05170	COG1902	pentaerythritol trinitrate reductase activity
FJ654_RS05175	COG3509	depolymerase
FJ654_RS05195	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS05220	COG0725	ABC transporter, periplasmic molybdate-binding protein
FJ654_RS05245	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FJ654_RS05260	COG2706	6-phosphogluconolactonase activity
FJ654_RS05275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FJ654_RS05315	COG4249	Peptidase C14 caspase catalytic subunit p20
FJ654_RS05315	COG2319	Wd-40 repeat
FJ654_RS05360	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FJ654_RS05375	COG0789	Transcriptional regulator
FJ654_RS05385	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS05405	COG0714	Associated with various cellular activities
FJ654_RS05425	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FJ654_RS05435	COG2207	Transcriptional regulator
FJ654_RS05435	COG1609	Transcriptional regulator
FJ654_RS05470	COG2205	protein histidine kinase activity
FJ654_RS05475	COG0745	RESPONSE REGULATOR receiver
FJ654_RS05485	COG1404	Belongs to the peptidase S8 family
FJ654_RS05505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJ654_RS05515	COG0640	Transcriptional regulator
FJ654_RS05520	COG2226	methyltransferase
FJ654_RS05550	COG3629	intracellular signal transduction
FJ654_RS05550	COG3903	Transcriptional regulator
FJ654_RS05585	COG0791	NLP P60 protein
FJ654_RS05595	COG2311	Membrane
FJ654_RS05655	COG3903	Transcriptional regulator
FJ654_RS05655	COG3629	intracellular signal transduction
FJ654_RS05660	COG0432	Pfam Uncharacterised protein family UPF0047
FJ654_RS05665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJ654_RS05670	COG1116	anion transmembrane transporter activity
FJ654_RS05680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS05685	COG0492	ferredoxin-NADP+ reductase activity
FJ654_RS05695	COG1132	(ABC) transporter
FJ654_RS05705	COG1301	dicarboxylic acid transport
FJ654_RS05720	COG1132	(ABC) transporter
FJ654_RS05725	COG1132	(ABC) transporter
FJ654_RS05735	COG0254	rRNA binding
FJ654_RS05750	COG1946	Acyl-CoA thioesterase
FJ654_RS05760	COG2018	Roadblock/LC7 domain
FJ654_RS05835	COG3239	Fatty acid desaturase
FJ654_RS05840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FJ654_RS05860	COG2115	Belongs to the xylose isomerase family
FJ654_RS05870	COG1940	carbohydrate kinase activity
FJ654_RS05890	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS05920	COG3509	depolymerase
FJ654_RS05950	COG3345	alpha-galactosidase
FJ654_RS05975	COG0702	epimerase
FJ654_RS05990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS05995	COG2124	cytochrome p450
FJ654_RS06005	COG0477	Major facilitator Superfamily
FJ654_RS06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS06080	COG0326	Molecular chaperone. Has ATPase activity
FJ654_RS06090	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FJ654_RS06090	COG3408	Glycogen debranching enzyme
FJ654_RS06105	COG2182	Extracellular solute-binding protein
FJ654_RS06160	COG4176	ABC-type proline glycine betaine transport system permease component
FJ654_RS06165	COG0517	IMP dehydrogenase activity
FJ654_RS06165	COG4175	Glycine betaine
FJ654_RS06170	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS06200	COG2172	sigma factor antagonist activity
FJ654_RS06205	COG1366	Belongs to the anti-sigma-factor antagonist family
FJ654_RS06210	COG1366	Belongs to the anti-sigma-factor antagonist family
FJ654_RS06225	COG1191	sigma factor activity
FJ654_RS06240	COG4638	Rieske (2fe-2S)
FJ654_RS06245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJ654_RS06250	COG2146	nitrite reductase [NAD(P)H] activity
FJ654_RS06260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FJ654_RS06320	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS06325	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS06355	COG1396	sequence-specific DNA binding
FJ654_RS06355	COG3800	Transcriptional regulator
FJ654_RS06360	COG0492	ferredoxin-NADP+ reductase activity
FJ654_RS06365	COG1793	dna ligase
FJ654_RS06385	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS06395	COG0242	peptide deformylase activity
FJ654_RS06405	COG3442	glutamine amidotransferase
FJ654_RS06410	COG0205	6-phosphofructokinase activity
FJ654_RS06425	COG0515	serine threonine protein kinase
FJ654_RS06435	COG3275	phosphorelay sensor kinase activity
FJ654_RS06440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJ654_RS06450	COG3279	Response regulator of the LytR AlgR family
FJ654_RS06455	COG1522	sequence-specific DNA binding
FJ654_RS06460	COG1834	amidinotransferase
FJ654_RS06465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FJ654_RS06495	COG0829	nickel cation binding
FJ654_RS06500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FJ654_RS06510	COG0804	urea catabolic process
FJ654_RS06515	COG0832	Belongs to the urease beta subunit family
FJ654_RS06520	COG0831	urea catabolic process
FJ654_RS06525	COG1309	transcriptional regulator
FJ654_RS06540	COG0740	serine-type endopeptidase activity
FJ654_RS06550	COG0791	NLP P60 protein
FJ654_RS06550	COG0741	lytic transglycosylase activity
FJ654_RS06580	COG0156	8-amino-7-oxononanoate synthase activity
FJ654_RS06585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FJ654_RS06590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FJ654_RS06595	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FJ654_RS06605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FJ654_RS06610	COG2226	methyltransferase
FJ654_RS06625	COG1136	(ABC) transporter
FJ654_RS06630	COG1136	(ABC) transporter
FJ654_RS06630	COG0577	efflux transmembrane transporter activity
FJ654_RS06640	COG0456	acetyltransferase
FJ654_RS06665	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FJ654_RS06670	COG3663	DNA glycosylase
FJ654_RS06685	COG1131	(ABC) transporter
FJ654_RS06690	COG4585	Histidine kinase
FJ654_RS06695	COG2197	response regulator
FJ654_RS06700	COG1940	carbohydrate kinase activity
FJ654_RS06705	COG2188	Transcriptional regulator
FJ654_RS06710	COG1595	DNA-templated transcription, initiation
FJ654_RS06715	COG0596	Alpha beta hydrolase
FJ654_RS06730	COG0626	cystathionine gamma-synthase activity
FJ654_RS06755	COG1522	sequence-specific DNA binding
FJ654_RS06760	COG0419	ATPase involved in DNA repair
FJ654_RS06765	COG0420	3'-5' exonuclease activity
FJ654_RS06770	COG1739	Uncharacterized protein family UPF0029
FJ654_RS06785	COG1832	CoA-binding protein
FJ654_RS06790	COG0531	amino acid
FJ654_RS06800	COG0640	Transcriptional regulator
FJ654_RS06825	COG0110	maltose O-acetyltransferase activity
FJ654_RS06845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FJ654_RS06865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FJ654_RS06875	COG0183	Belongs to the thiolase family
FJ654_RS06885	COG1968	undecaprenyl-diphosphatase activity
FJ654_RS06900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS06910	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FJ654_RS06920	COG2318	DinB family
FJ654_RS06935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FJ654_RS06940	COG0747	negative chemotaxis
FJ654_RS06980	COG0583	DNA-binding transcription factor activity
FJ654_RS07000	COG0697	spore germination
FJ654_RS07030	COG0657	acetylesterase activity
FJ654_RS07035	COG1595	DNA-templated transcription, initiation
FJ654_RS07085	COG1609	Transcriptional regulator
FJ654_RS07095	COG0395	ABC-type sugar transport system, permease component
FJ654_RS07100	COG1175	transmembrane transport
FJ654_RS07120	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FJ654_RS07120	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FJ654_RS07130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FJ654_RS07150	COG1716	ATPase activity
FJ654_RS07170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FJ654_RS07205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FJ654_RS07215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJ654_RS07235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJ654_RS07240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FJ654_RS07245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FJ654_RS07300	COG2814	Major facilitator Superfamily
FJ654_RS07305	COG4336	lyase activity
FJ654_RS07310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FJ654_RS07315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FJ654_RS07320	COG1984	allophanate hydrolase subunit 2
FJ654_RS07325	COG2755	lipolytic protein G-D-S-L family
FJ654_RS07330	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS07375	COG2364	Membrane
FJ654_RS07385	COG2270	Major facilitator Superfamily
FJ654_RS07400	COG1216	Glycosyl transferase, family 2
FJ654_RS07435	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS07485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FJ654_RS07490	COG0140	phosphoribosyl-ATP diphosphatase activity
FJ654_RS07495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FJ654_RS07500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FJ654_RS07500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FJ654_RS07505	COG3201	nicotinamide mononucleotide transporter
FJ654_RS07515	COG1846	Transcriptional regulator
FJ654_RS07515	COG1940	carbohydrate kinase activity
FJ654_RS07520	COG2223	nitrite transmembrane transporter activity
FJ654_RS07540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJ654_RS07555	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FJ654_RS07575	COG2186	Transcriptional regulator
FJ654_RS07590	COG0531	amino acid
FJ654_RS07600	COG2390	Transcriptional regulator
FJ654_RS07605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FJ654_RS07610	COG2409	Drug exporters of the RND superfamily
FJ654_RS07620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJ654_RS07640	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FJ654_RS07650	COG1758	RNA polymerase activity
FJ654_RS07655	COG0194	GDP metabolic process
FJ654_RS07665	COG0284	orotidine-5'-phosphate decarboxylase activity
FJ654_RS07670	COG0167	dihydroorotate dehydrogenase activity
FJ654_RS07675	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FJ654_RS07680	COG0505	Belongs to the CarA family
FJ654_RS07690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FJ654_RS07695	COG0540	Belongs to the ATCase OTCase family
FJ654_RS07700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FJ654_RS07710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FJ654_RS07715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FJ654_RS07720	COG0006	proline dipeptidase activity
FJ654_RS07730	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FJ654_RS07735	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FJ654_RS07740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FJ654_RS07745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FJ654_RS07760	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FJ654_RS07765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FJ654_RS07785	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FJ654_RS07800	COG1131	(ABC) transporter
FJ654_RS07810	COG4585	Histidine kinase
FJ654_RS07815	COG2197	response regulator
FJ654_RS07820	COG0124	histidyl-tRNA synthetase
FJ654_RS07830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FJ654_RS07835	COG1196	nuclear chromosome segregation
FJ654_RS07840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FJ654_RS07850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FJ654_RS07855	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJ654_RS07860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJ654_RS07870	COG2255	four-way junction helicase activity
FJ654_RS07875	COG0632	four-way junction helicase activity
FJ654_RS07880	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FJ654_RS07885	COG0217	transcriptional regulatory protein
FJ654_RS07890	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FJ654_RS07895	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FJ654_RS07905	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS07910	COG1560	Kdo2-lipid A biosynthetic process
FJ654_RS07915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FJ654_RS07935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJ654_RS07940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FJ654_RS07955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FJ654_RS07985	COG0395	ABC-type sugar transport system, permease component
FJ654_RS07990	COG1175	transmembrane transport
FJ654_RS07995	COG1653	transport
FJ654_RS08040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJ654_RS08100	COG1648	precorrin-2 dehydrogenase activity
FJ654_RS08100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FJ654_RS08105	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FJ654_RS08120	COG1464	Belongs to the NlpA lipoprotein family
FJ654_RS08125	COG2011	ABC-type metal ion transport system permease component
FJ654_RS08130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FJ654_RS08165	COG0204	Acyl-transferase
FJ654_RS08165	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS08170	COG0477	Major facilitator Superfamily
FJ654_RS08185	COG0165	Argininosuccinate lyase
FJ654_RS08200	COG2205	protein histidine kinase activity
FJ654_RS08205	COG0745	RESPONSE REGULATOR receiver
FJ654_RS08220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FJ654_RS08220	COG1017	nitric oxide dioxygenase activity
FJ654_RS08235	COG1438	arginine binding
FJ654_RS08240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FJ654_RS08245	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FJ654_RS08250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FJ654_RS08255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FJ654_RS08300	COG0697	spore germination
FJ654_RS08310	COG1649	PFAM Uncharacterised BCR, COG1649
FJ654_RS08340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJ654_RS08340	COG0072	phenylalanine-tRNA ligase activity
FJ654_RS08345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FJ654_RS08350	COG5002	protein histidine kinase activity
FJ654_RS08355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJ654_RS08360	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FJ654_RS08365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FJ654_RS08370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FJ654_RS08425	COG0174	glutamine synthetase
FJ654_RS08435	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FJ654_RS08465	COG0517	IMP dehydrogenase activity
FJ654_RS08465	COG4175	Glycine betaine
FJ654_RS08470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJ654_RS08565	COG0805	protein transport
FJ654_RS08570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJ654_RS08600	COG0545	Peptidyl-prolyl cis-trans isomerase
FJ654_RS08605	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FJ654_RS08615	COG1609	Transcriptional regulator
FJ654_RS08620	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FJ654_RS08625	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FJ654_RS08640	COG4122	O-methyltransferase activity
FJ654_RS08645	COG1222	aaa ATPase
FJ654_RS08670	COG0517	IMP dehydrogenase activity
FJ654_RS08670	COG1994	Peptidase M50
FJ654_RS08680	COG2197	response regulator
FJ654_RS08685	COG4166	transmembrane transport
FJ654_RS08690	COG0747	negative chemotaxis
FJ654_RS08695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FJ654_RS08700	COG0646	methionine synthase
FJ654_RS08700	COG1410	methionine synthase
FJ654_RS08705	COG1414	Transcriptional regulator
FJ654_RS08710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FJ654_RS08715	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FJ654_RS08720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FJ654_RS08730	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FJ654_RS08740	COG1129	ABC transporter
FJ654_RS08750	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FJ654_RS08755	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FJ654_RS08760	COG0235	Class ii aldolase
FJ654_RS08765	COG0235	Class ii aldolase
FJ654_RS08765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FJ654_RS08770	COG2186	Transcriptional regulator
FJ654_RS08785	COG0215	cysteine-tRNA ligase activity
FJ654_RS08800	COG0588	phosphoglycerate mutase activity
FJ654_RS08805	COG0598	Magnesium transport protein CorA
FJ654_RS08815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS08820	COG0667	Aldo Keto reductase
FJ654_RS08865	COG0308	aminopeptidase N
FJ654_RS08870	COG3012	SEC-C Motif Domain Protein
FJ654_RS08875	COG2186	Transcriptional regulator
FJ654_RS08880	COG3265	gluconokinase activity
FJ654_RS08915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FJ654_RS08920	COG2205	protein histidine kinase activity
FJ654_RS08925	COG0745	RESPONSE REGULATOR receiver
FJ654_RS08930	COG2149	membrane
FJ654_RS08950	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS08960	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS08970	COG3876	Protein conserved in bacteria
FJ654_RS09025	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS09070	COG2851	Citrate transporter
FJ654_RS09075	COG0243	molybdopterin cofactor binding
FJ654_RS09080	COG1309	transcriptional regulator
FJ654_RS09090	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FJ654_RS09095	COG2188	Transcriptional regulator
FJ654_RS09130	COG1595	DNA-templated transcription, initiation
FJ654_RS09145	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FJ654_RS09150	COG2815	serine threonine protein kinase
FJ654_RS09150	COG0515	serine threonine protein kinase
FJ654_RS09155	COG2755	lipolytic protein G-D-S-L family
FJ654_RS09175	COG0463	Glycosyl transferase, family 2
FJ654_RS09185	COG1649	PFAM Uncharacterised BCR, COG1649
FJ654_RS09185	COG0726	polysaccharide deacetylase
FJ654_RS09210	COG1725	Transcriptional regulator
FJ654_RS09225	COG2226	methyltransferase
FJ654_RS09265	COG0587	DNA-directed DNA polymerase activity
FJ654_RS09330	COG0330	HflC and HflK could
FJ654_RS09350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS09365	COG1799	cell septum assembly
FJ654_RS09370	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS09375	COG0477	Major facilitator Superfamily
FJ654_RS09395	COG0671	phosphoesterase, PA-phosphatase related
FJ654_RS09415	COG0596	Alpha beta hydrolase
FJ654_RS09435	COG0411	ABC transporter
FJ654_RS09460	COG1160	GTP binding
FJ654_RS09470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FJ654_RS09515	COG1187	pseudouridine synthase activity
FJ654_RS09520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FJ654_RS09525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FJ654_RS09540	COG0686	Belongs to the AlaDH PNT family
FJ654_RS09550	COG0494	nUDIX hydrolase
FJ654_RS09555	COG0504	CTP synthase activity
FJ654_RS09560	COG3387	PFAM Glycoside hydrolase 15-related
FJ654_RS09580	COG0297	glycogen (starch) synthase activity
FJ654_RS09585	COG0497	DNA recombination
FJ654_RS09590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FJ654_RS09610	COG1120	ATPase activity
FJ654_RS09615	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FJ654_RS09620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FJ654_RS09625	COG0647	UMP catabolic process
FJ654_RS09665	COG2094	Belongs to the DNA glycosylase MPG family
FJ654_RS09675	COG1881	PFAM PEBP family protein
FJ654_RS09695	COG1119	ATPase activity
FJ654_RS09715	COG2197	response regulator
FJ654_RS09725	COG4221	oxidoreductase activity
FJ654_RS09730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FJ654_RS09740	COG1716	ATPase activity
FJ654_RS09740	COG1131	(ABC) transporter
FJ654_RS09740	COG0842	Transport permease protein
FJ654_RS09750	COG0560	Phosphoserine phosphatase
FJ654_RS09750	COG3830	Belongs to the UPF0237 family
FJ654_RS09755	COG0588	phosphoglycerate mutase activity
FJ654_RS09770	COG2186	Transcriptional regulator
FJ654_RS09790	COG0312	modulator of DNA gyrase
FJ654_RS09800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FJ654_RS09820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FJ654_RS09825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJ654_RS09845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FJ654_RS09855	COG1063	alcohol dehydrogenase
FJ654_RS09875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FJ654_RS09890	COG3387	PFAM Glycoside hydrolase 15-related
FJ654_RS09930	COG1024	Enoyl-CoA hydratase
FJ654_RS09940	COG0488	(ABC) transporter
FJ654_RS09965	COG0235	Class ii aldolase
FJ654_RS09980	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FJ654_RS09985	COG1492	cobalamin metabolic process
FJ654_RS10005	COG1797	cobyrinic acid a,c-diamide synthase activity
FJ654_RS10040	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
FJ654_RS10060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FJ654_RS10065	COG1126	abc transporter atp-binding protein
FJ654_RS10070	COG0765	amino acid transport
FJ654_RS10075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJ654_RS10080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FJ654_RS10085	COG2318	DinB family
FJ654_RS10090	COG0456	acetyltransferase
FJ654_RS10095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FJ654_RS10100	COG1917	Cupin 2, conserved barrel domain protein
FJ654_RS10105	COG5285	phytanoyl-CoA dioxygenase
FJ654_RS10110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FJ654_RS10130	COG1414	Transcriptional regulator
FJ654_RS10145	COG2252	PERMEase
FJ654_RS10150	COG1595	DNA-templated transcription, initiation
FJ654_RS10175	COG4677	pectinesterase activity
FJ654_RS10180	COG4677	pectinesterase activity
FJ654_RS10185	COG3866	Pectate lyase
FJ654_RS10205	COG0673	inositol 2-dehydrogenase activity
FJ654_RS10215	COG0395	ABC-type sugar transport system, permease component
FJ654_RS10220	COG1175	transmembrane transport
FJ654_RS10230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJ654_RS10235	COG1802	Transcriptional regulator
FJ654_RS10240	COG1234	tRNA 3'-trailer cleavage
FJ654_RS10260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJ654_RS10265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJ654_RS10275	COG1349	DNA-binding transcription factor activity
FJ654_RS10290	COG0395	ABC-type sugar transport system, permease component
FJ654_RS10295	COG1063	alcohol dehydrogenase
FJ654_RS10305	COG1309	transcriptional regulator
FJ654_RS10310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS10315	COG1609	Transcriptional regulator
FJ654_RS10335	COG2017	converts alpha-aldose to the beta-anomer
FJ654_RS10340	COG1609	Transcriptional regulator
FJ654_RS10350	COG1802	Transcriptional regulator
FJ654_RS10385	COG1295	ribonuclease BN
FJ654_RS10385	COG1959	2 iron, 2 sulfur cluster binding
FJ654_RS10405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJ654_RS10415	COG1595	DNA-templated transcription, initiation
FJ654_RS10420	COG2171	N-acyltransferase activity
FJ654_RS10425	COG3226	Transcriptional regulator
FJ654_RS10430	COG2076	Multidrug Resistance protein
FJ654_RS10440	COG2151	metal-sulfur cluster biosynthetic enzyme
FJ654_RS10445	COG0822	iron-sulfur transferase activity
FJ654_RS10450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FJ654_RS10455	COG0396	ATPase activity
FJ654_RS10465	COG0719	Fe-S assembly protein
FJ654_RS10480	COG2746	aminoglycoside 3-N-acetyltransferase activity
FJ654_RS10485	COG1131	(ABC) transporter
FJ654_RS10495	COG1612	heme a metabolic process
FJ654_RS10515	COG0109	protoheme IX farnesyltransferase activity
FJ654_RS10530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FJ654_RS10545	COG0363	glucosamine-6-phosphate deaminase activity
FJ654_RS10550	COG0166	Belongs to the GPI family
FJ654_RS10560	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FJ654_RS10565	COG0149	triose-phosphate isomerase activity
FJ654_RS10570	COG0126	phosphoglycerate kinase activity
FJ654_RS10575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FJ654_RS10585	COG1481	regulation of sporulation
FJ654_RS10590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FJ654_RS10595	COG1660	Displays ATPase and GTPase activities
FJ654_RS10600	COG0322	excinuclease ABC activity
FJ654_RS10615	COG1609	Transcriptional regulator
FJ654_RS10625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FJ654_RS10640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJ654_RS10645	COG0765	amino acid transport
FJ654_RS10655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FJ654_RS10660	COG1619	proteins homologs of microcin C7 resistance protein MccF
FJ654_RS10665	COG0387	Pfam Sodium calcium exchanger
FJ654_RS10690	COG0556	nucleotide-excision repair
FJ654_RS10700	COG0584	glycerophosphoryl diester phosphodiesterase
FJ654_RS10705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FJ654_RS10715	COG2313	pseudouridylate synthase activity
FJ654_RS10720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FJ654_RS10720	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FJ654_RS10725	COG2226	methyltransferase
FJ654_RS10730	COG0598	Magnesium transport protein CorA
FJ654_RS10760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FJ654_RS10765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FJ654_RS10790	COG1132	(ABC) transporter
FJ654_RS10805	COG0402	S-adenosylhomocysteine deaminase activity
FJ654_RS10840	COG1953	Uracil, thiamine, allantoin
FJ654_RS10845	COG1802	Transcriptional regulator
FJ654_RS10880	COG0237	dephospho-CoA kinase activity
FJ654_RS10900	COG1643	Atp-dependent helicase
FJ654_RS10940	COG2050	protein possibly involved in aromatic compounds catabolism
FJ654_RS11000	COG0737	Belongs to the 5'-nucleotidase family
FJ654_RS11020	COG4566	intracellular signal transduction
FJ654_RS11025	COG0287	Prephenate dehydrogenase
FJ654_RS11025	COG1605	Chorismate mutase
FJ654_RS11045	COG2304	oxidoreductase activity
FJ654_RS11065	COG0070	glutamate synthase
FJ654_RS11065	COG0069	glutamate synthase activity
FJ654_RS11065	COG0067	glutamate synthase
FJ654_RS11095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS11100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FJ654_RS11110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FJ654_RS11120	COG0159	tryptophan synthase activity
FJ654_RS11125	COG0133	tryptophan synthase activity
FJ654_RS11135	COG0134	indole-3-glycerol-phosphate synthase activity
FJ654_RS11155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJ654_RS11160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FJ654_RS11170	COG0107	imidazoleglycerol-phosphate synthase activity
FJ654_RS11175	COG0251	oxidation-reduction process
FJ654_RS11180	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FJ654_RS11185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FJ654_RS11190	COG0131	Imidazoleglycerol-phosphate dehydratase
FJ654_RS11195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJ654_RS11200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FJ654_RS11220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FJ654_RS11240	COG1432	Conserved Protein
FJ654_RS11245	COG0587	DNA-directed DNA polymerase activity
FJ654_RS11300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FJ654_RS11315	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FJ654_RS11320	COG3599	regulation of cell shape
FJ654_RS11330	COG1799	cell septum assembly
FJ654_RS11340	COG1496	oxidoreductase activity
FJ654_RS11345	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FJ654_RS11355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FJ654_RS11365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FJ654_RS11370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FJ654_RS11380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FJ654_RS11395	COG0275	rRNA processing
FJ654_RS11405	COG0714	Associated with various cellular activities
FJ654_RS11435	COG1126	abc transporter atp-binding protein
FJ654_RS11445	COG1309	transcriptional regulator
FJ654_RS11470	COG0352	thiamine-phosphate diphosphorylase activity
FJ654_RS11490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FJ654_RS11490	COG2022	thiamine diphosphate biosynthetic process
FJ654_RS11500	COG2022	thiamine diphosphate biosynthetic process
FJ654_RS11505	COG2815	serine threonine protein kinase
FJ654_RS11505	COG0515	serine threonine protein kinase
FJ654_RS11510	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FJ654_RS11520	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FJ654_RS11525	COG2193	ferroxidase activity
FJ654_RS11530	COG0243	molybdopterin cofactor binding
FJ654_RS11535	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FJ654_RS11550	COG0205	6-phosphofructokinase activity
FJ654_RS11555	COG2197	response regulator
FJ654_RS11585	COG1940	carbohydrate kinase activity
FJ654_RS11595	COG0003	Pfam Anion-transporting ATPase
FJ654_RS11640	COG0791	NLP P60 protein
FJ654_RS11665	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJ654_RS11665	COG0515	serine threonine protein kinase
FJ654_RS11670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FJ654_RS11675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FJ654_RS11680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FJ654_RS11685	COG0723	plastoquinol--plastocyanin reductase activity
FJ654_RS11690	COG2010	Cytochrome c
FJ654_RS11695	COG1845	cytochrome c oxidase, subunit III
FJ654_RS11705	COG1376	ErfK ybiS ycfS ynhG family protein
FJ654_RS11715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FJ654_RS11720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FJ654_RS11730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS11750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FJ654_RS11760	COG4941	Belongs to the sigma-70 factor family
FJ654_RS11765	COG3795	YCII-related domain
FJ654_RS11770	COG2197	response regulator
FJ654_RS11775	COG4585	Histidine kinase
FJ654_RS11795	COG2226	methyltransferase
FJ654_RS11815	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FJ654_RS11820	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FJ654_RS11820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FJ654_RS11835	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FJ654_RS11845	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FJ654_RS11850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FJ654_RS11855	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJ654_RS11870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FJ654_RS11925	COG0321	lipoyl(octanoyl) transferase activity
FJ654_RS11930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FJ654_RS11955	COG0174	glutamine synthetase
FJ654_RS11970	COG0501	Belongs to the peptidase M48B family
FJ654_RS11990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS12030	COG0745	RESPONSE REGULATOR receiver
FJ654_RS12045	COG4585	Histidine kinase
FJ654_RS12050	COG2197	response regulator
FJ654_RS12075	COG1309	transcriptional regulator
FJ654_RS12110	COG0366	Alpha amylase catalytic
FJ654_RS12115	COG3833	ABC-type maltose transport systems, permease component
FJ654_RS12120	COG1175	transmembrane transport
FJ654_RS12125	COG1653	transport
FJ654_RS12130	COG1609	Transcriptional regulator
FJ654_RS12140	COG0583	DNA-binding transcription factor activity
FJ654_RS12145	COG0697	spore germination
FJ654_RS12150	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FJ654_RS12175	COG0174	glutamine synthetase
FJ654_RS12205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FJ654_RS12210	COG0477	Major facilitator Superfamily
FJ654_RS12225	COG2814	Major facilitator Superfamily
FJ654_RS12245	COG1994	Peptidase M50
FJ654_RS12290	COG2822	iron ion transport
FJ654_RS12295	COG2837	iron assimilation
FJ654_RS12300	COG0672	)-iron permease
FJ654_RS12330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJ654_RS12335	COG2814	Major facilitator Superfamily
FJ654_RS12355	COG1136	(ABC) transporter
FJ654_RS12390	COG3903	Transcriptional regulator
FJ654_RS12390	COG3629	intracellular signal transduction
FJ654_RS12395	COG1595	DNA-templated transcription, initiation
FJ654_RS12400	COG0464	growth
FJ654_RS12405	COG1404	Belongs to the peptidase S8 family
FJ654_RS12410	COG1674	ftsk spoiiie
FJ654_RS12485	COG1172	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS12490	COG1129	ABC transporter
FJ654_RS12500	COG1609	Transcriptional regulator
FJ654_RS12550	COG0557	exoribonuclease II activity
FJ654_RS12555	COG3022	response to hydroperoxide
FJ654_RS12560	COG0800	Aldolase
FJ654_RS12575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FJ654_RS12585	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS12595	COG2030	dehydratase
FJ654_RS12600	COG4585	Histidine kinase
FJ654_RS12605	COG2197	response regulator
FJ654_RS12625	COG0477	Major facilitator Superfamily
FJ654_RS12635	COG0860	N-Acetylmuramoyl-L-alanine amidase
FJ654_RS12645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS12665	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS12670	COG1309	transcriptional regulator
FJ654_RS12710	COG3845	ABC transporter
FJ654_RS12730	COG3619	membrane
FJ654_RS12735	COG2267	carboxylic ester hydrolase activity
FJ654_RS12755	COG0183	Belongs to the thiolase family
FJ654_RS12760	COG2124	cytochrome p450
FJ654_RS12775	COG4122	O-methyltransferase activity
FJ654_RS12900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJ654_RS12925	COG1358	cellular component organization or biogenesis
FJ654_RS12975	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FJ654_RS12980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FJ654_RS12990	COG0477	Major facilitator Superfamily
FJ654_RS12995	COG1309	transcriptional regulator
FJ654_RS13010	COG0667	Aldo Keto reductase
FJ654_RS13015	COG0789	Transcriptional regulator
FJ654_RS13030	COG1741	Belongs to the pirin family
FJ654_RS13045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJ654_RS13050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJ654_RS13055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS13105	COG1764	response to oxidative stress
FJ654_RS13110	COG2130	NADP-dependent
FJ654_RS13125	COG1172	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS13130	COG1172	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS13140	COG1879	ABC-type sugar transport system periplasmic component
FJ654_RS13145	COG1609	Transcriptional regulator
FJ654_RS13150	COG4948	Mandelate Racemase Muconate Lactonizing
FJ654_RS13170	COG1129	ABC transporter
FJ654_RS13175	COG4214	carbohydrate transport
FJ654_RS13185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJ654_RS13285	COG3386	PFAM SMP-30 Gluconolaconase
FJ654_RS13290	COG1414	Transcriptional regulator
FJ654_RS13320	COG4981	capsule polysaccharide biosynthetic process
FJ654_RS13340	COG2835	tetraacyldisaccharide 4'-kinase activity
FJ654_RS13370	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS13375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FJ654_RS13375	COG0825	malonyl-CoA metabolic process
FJ654_RS13380	COG1077	Cell shape determining protein MreB Mrl
FJ654_RS13395	COG0531	amino acid
FJ654_RS13410	COG0121	glutamine amidotransferase
FJ654_RS13435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FJ654_RS13465	COG1070	Carbohydrate kinase
FJ654_RS13480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FJ654_RS13485	COG0358	DNA primase activity
FJ654_RS13495	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FJ654_RS13505	COG2949	membrane
FJ654_RS13530	COG0243	molybdopterin cofactor binding
FJ654_RS13570	COG3896	Chloramphenicol phosphotransferase-like protein
FJ654_RS13580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJ654_RS13585	COG2146	nitrite reductase [NAD(P)H] activity
FJ654_RS13585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJ654_RS13605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS13630	COG0574	Belongs to the PEP-utilizing enzyme family
FJ654_RS13630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FJ654_RS13635	COG1846	Transcriptional regulator
FJ654_RS13635	COG1940	carbohydrate kinase activity
FJ654_RS13640	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FJ654_RS13670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJ654_RS13685	COG0477	Major facilitator Superfamily
FJ654_RS13695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FJ654_RS13705	COG0667	Aldo Keto reductase
FJ654_RS13710	COG0423	glycine-tRNA ligase activity
FJ654_RS13720	COG1121	(ABC) transporter
FJ654_RS13725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FJ654_RS13740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FJ654_RS13745	COG1381	Involved in DNA repair and RecF pathway recombination
FJ654_RS13765	COG1595	DNA-templated transcription, initiation
FJ654_RS13780	COG2197	response regulator
FJ654_RS13785	COG4585	Histidine kinase
FJ654_RS13790	COG2409	Drug exporters of the RND superfamily
FJ654_RS13800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJ654_RS13820	COG2723	6-phospho-beta-galactosidase activity
FJ654_RS13840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FJ654_RS13885	COG2315	Protein conserved in bacteria
FJ654_RS13895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FJ654_RS13910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS13915	COG4948	Mandelate Racemase Muconate Lactonizing
FJ654_RS13920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJ654_RS13935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FJ654_RS13940	COG1234	tRNA 3'-trailer cleavage
FJ654_RS13945	COG0537	adenosine 5'-monophosphoramidase activity
FJ654_RS13950	COG4946	Tricorn protease homolog
FJ654_RS13950	COG0793	Belongs to the peptidase S41A family
FJ654_RS13975	COG0484	heat shock protein binding
FJ654_RS13980	COG1420	regulation of RNA biosynthetic process
FJ654_RS14010	COG0745	RESPONSE REGULATOR receiver
FJ654_RS14020	COG0481	GTPase activity
FJ654_RS14025	COG0268	Binds directly to 16S ribosomal RNA
FJ654_RS14050	COG1234	tRNA 3'-trailer cleavage
FJ654_RS14055	COG1596	polysaccharide export
FJ654_RS14055	COG1555	photosystem II stabilization
FJ654_RS14065	COG1307	EDD domain protein, DegV family
FJ654_RS14075	COG0495	leucyl-tRNA aminoacylation
FJ654_RS14085	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FJ654_RS14115	COG0588	phosphoglycerate mutase activity
FJ654_RS14120	COG0799	negative regulation of ribosome biogenesis
FJ654_RS14130	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FJ654_RS14135	COG0501	Belongs to the peptidase M48B family
FJ654_RS14150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FJ654_RS14160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FJ654_RS14170	COG1215	transferase activity, transferring glycosyl groups
FJ654_RS14185	COG3540	Alkaline phosphatase
FJ654_RS14195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FJ654_RS14200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FJ654_RS14205	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FJ654_RS14235	COG1530	ribonuclease E activity
FJ654_RS14265	COG0539	negative regulation of cytoplasmic translation
FJ654_RS14295	COG0772	Belongs to the SEDS family
FJ654_RS14300	COG0768	penicillin binding
FJ654_RS14315	COG1077	Cell shape determining protein MreB Mrl
FJ654_RS14320	COG0105	UTP biosynthetic process
FJ654_RS14330	COG0285	dihydrofolate synthase activity
FJ654_RS14335	COG0525	valine-tRNA ligase activity
FJ654_RS14345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FJ654_RS14350	COG0740	serine-type endopeptidase activity
FJ654_RS14355	COG0740	serine-type endopeptidase activity
FJ654_RS14360	COG0544	peptidyl-prolyl cis-trans isomerase activity
FJ654_RS14380	COG3594	Acyltransferase
FJ654_RS14400	COG4552	Acetyltransferase involved in intracellular survival and related
FJ654_RS14410	COG0698	ribose 5-phosphate isomerase
FJ654_RS14415	COG1113	amino acid transport
FJ654_RS14450	COG1940	carbohydrate kinase activity
FJ654_RS14460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJ654_RS14465	COG1116	anion transmembrane transporter activity
FJ654_RS14470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS14490	COG0588	phosphoglycerate mutase activity
FJ654_RS14505	COG1070	Carbohydrate kinase
FJ654_RS14515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FJ654_RS14610	COG0697	spore germination
FJ654_RS14615	COG1846	Transcriptional regulator
FJ654_RS14640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS14670	COG1136	(ABC) transporter
FJ654_RS14685	COG0668	transmembrane transport
FJ654_RS14695	COG1940	carbohydrate kinase activity
FJ654_RS14705	COG1175	transmembrane transport
FJ654_RS14710	COG0395	ABC-type sugar transport system, permease component
FJ654_RS14715	COG1486	melibiose metabolic process
FJ654_RS14770	COG2346	COG2346, Truncated hemoglobins
FJ654_RS14785	COG1136	(ABC) transporter
FJ654_RS14785	COG0577	efflux transmembrane transporter activity
FJ654_RS14840	COG0629	single-stranded DNA binding
FJ654_RS14860	COG1720	tRNA m6t6A37 methyltransferase activity
FJ654_RS14865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FJ654_RS14880	COG2304	oxidoreductase activity
FJ654_RS14920	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS14935	COG0728	peptidoglycan biosynthetic process
FJ654_RS14945	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS14990	COG1316	TRANSCRIPTIONal
FJ654_RS15015	COG1131	(ABC) transporter
FJ654_RS15035	COG3962	Belongs to the TPP enzyme family
FJ654_RS15040	COG3718	enzyme involved in inositol metabolism
FJ654_RS15050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS15065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FJ654_RS15070	COG1063	alcohol dehydrogenase
FJ654_RS15075	COG2409	Drug exporters of the RND superfamily
FJ654_RS15105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FJ654_RS15125	COG1609	Transcriptional regulator
FJ654_RS15130	COG1129	ABC transporter
FJ654_RS15140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS15145	COG1869	D-ribose catabolic process
FJ654_RS15160	COG0673	inositol 2-dehydrogenase activity
FJ654_RS15190	COG0456	acetyltransferase
FJ654_RS15190	COG1846	Transcriptional regulator
FJ654_RS15210	COG0456	acetyltransferase
FJ654_RS15225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FJ654_RS15235	COG1472	Belongs to the glycosyl hydrolase 3 family
FJ654_RS15270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FJ654_RS15285	COG2356	endonuclease I
FJ654_RS15290	COG0028	Belongs to the TPP enzyme family
FJ654_RS15300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJ654_RS15315	COG1946	Acyl-CoA thioesterase
FJ654_RS15325	COG1309	transcriptional regulator
FJ654_RS15330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FJ654_RS15345	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS15365	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FJ654_RS15390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJ654_RS15395	COG0589	response to stress
FJ654_RS15405	COG4977	sequence-specific DNA binding
FJ654_RS15410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FJ654_RS15420	COG0583	DNA-binding transcription factor activity
FJ654_RS15445	COG0395	ABC-type sugar transport system, permease component
FJ654_RS15460	COG3345	alpha-galactosidase
FJ654_RS15465	COG0395	ABC-type sugar transport system, permease component
FJ654_RS15470	COG1175	transmembrane transport
FJ654_RS15475	COG1653	transport
FJ654_RS15485	COG0745	RESPONSE REGULATOR receiver
FJ654_RS15510	COG0406	alpha-ribazole phosphatase activity
FJ654_RS15560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS15580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FJ654_RS15590	COG2226	methyltransferase
FJ654_RS15600	COG0477	Major facilitator Superfamily
FJ654_RS15610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJ654_RS15615	COG0765	amino acid transport
FJ654_RS15620	COG0765	amino acid transport
FJ654_RS15625	COG1126	abc transporter atp-binding protein
FJ654_RS15640	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS15650	COG3397	chitin binding
FJ654_RS15715	COG0673	inositol 2-dehydrogenase activity
FJ654_RS15720	COG4702	Belongs to the UPF0303 family
FJ654_RS15755	COG3764	Sortase (surface protein transpeptidase)
FJ654_RS15785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FJ654_RS15890	COG0071	Belongs to the small heat shock protein (HSP20) family
FJ654_RS15910	COG2733	membrane
FJ654_RS15925	COG4555	ABC transporter
FJ654_RS15940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FJ654_RS15980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FJ654_RS15990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FJ654_RS15995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FJ654_RS16000	COG1263	PTS System
FJ654_RS16005	COG1263	PTS System
FJ654_RS16010	COG1234	tRNA 3'-trailer cleavage
FJ654_RS16035	COG1113	amino acid transport
FJ654_RS16045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FJ654_RS16055	COG1335	isochorismatase
FJ654_RS16110	COG0277	FAD linked oxidase domain protein
FJ654_RS16135	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FJ654_RS16170	COG4948	Mandelate Racemase Muconate Lactonizing
FJ654_RS16195	COG3654	unkown
FJ654_RS16265	COG1674	ftsk spoiiie
FJ654_RS16310	COG2188	Transcriptional regulator
FJ654_RS16340	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FJ654_RS16355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FJ654_RS16370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FJ654_RS16380	COG1678	Uncharacterized ACR, COG1678
FJ654_RS16385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FJ654_RS16390	COG0776	regulation of translation
FJ654_RS16400	COG3973	AAA domain
FJ654_RS16400	COG3973	AAA domain
FJ654_RS16430	COG2223	nitrite transmembrane transporter activity
FJ654_RS16460	COG0583	DNA-binding transcription factor activity
FJ654_RS16475	COG1175	transmembrane transport
FJ654_RS16480	COG0395	ABC-type sugar transport system, permease component
FJ654_RS16485	COG1501	Belongs to the glycosyl hydrolase 31 family
FJ654_RS16510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FJ654_RS16515	COG0793	Belongs to the peptidase S41A family
FJ654_RS16520	COG2177	Part of the ABC transporter FtsEX involved in
FJ654_RS16525	COG2884	Cell division ATP-binding protein ftsE
FJ654_RS16540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FJ654_RS16545	COG0515	serine threonine protein kinase
FJ654_RS16550	COG0515	serine threonine protein kinase
FJ654_RS16565	COG1175	transmembrane transport
FJ654_RS16570	COG0395	ABC-type sugar transport system, permease component
FJ654_RS16580	COG1764	response to oxidative stress
FJ654_RS16585	COG1846	Transcriptional regulator
FJ654_RS16615	COG1134	teichoic acid transport
FJ654_RS16620	COG2902	Dehydrogenase
FJ654_RS16645	COG0653	protein targeting
FJ654_RS16650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FJ654_RS16655	COG3214	Protein conserved in bacteria
FJ654_RS16660	COG2197	response regulator
FJ654_RS16665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FJ654_RS16675	COG0823	Involved in the tonB-independent uptake of proteins
FJ654_RS16680	COG5002	protein histidine kinase activity
FJ654_RS16680	COG5000	phosphorelay sensor kinase activity
FJ654_RS16685	COG0745	RESPONSE REGULATOR receiver
FJ654_RS16690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FJ654_RS16710	COG0714	Associated with various cellular activities
FJ654_RS16755	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FJ654_RS16765	COG1482	cell wall glycoprotein biosynthetic process
FJ654_RS16775	COG2835	tetraacyldisaccharide 4'-kinase activity
FJ654_RS16780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJ654_RS16815	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FJ654_RS16820	COG0778	Nitroreductase
FJ654_RS16820	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FJ654_RS16845	COG1316	TRANSCRIPTIONal
FJ654_RS16850	COG1316	TRANSCRIPTIONal
FJ654_RS16855	COG1316	TRANSCRIPTIONal
FJ654_RS16860	COG1316	TRANSCRIPTIONal
FJ654_RS16875	COG1316	TRANSCRIPTIONal
FJ654_RS16880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FJ654_RS16890	COG1316	TRANSCRIPTIONal
FJ654_RS16910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FJ654_RS16970	COG2205	protein histidine kinase activity
FJ654_RS16975	COG0745	RESPONSE REGULATOR receiver
FJ654_RS16980	COG3104	oligopeptide transport
FJ654_RS17010	COG1366	Belongs to the anti-sigma-factor antagonist family
FJ654_RS17015	COG1191	sigma factor activity
FJ654_RS17025	COG1228	amidohydrolase
FJ654_RS17035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FJ654_RS17040	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FJ654_RS17090	COG1174	glycine betaine transport
FJ654_RS17095	COG1174	glycine betaine transport
FJ654_RS17110	COG4221	oxidoreductase activity
FJ654_RS17125	COG2755	lipolytic protein G-D-S-L family
FJ654_RS17130	COG0183	Belongs to the thiolase family
FJ654_RS17195	COG1136	(ABC) transporter
FJ654_RS17200	COG0577	efflux transmembrane transporter activity
FJ654_RS17205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FJ654_RS17210	COG1252	NADH dehydrogenase
FJ654_RS17230	COG0148	phosphopyruvate hydratase activity
FJ654_RS17315	COG0577	efflux transmembrane transporter activity
FJ654_RS17320	COG1136	(ABC) transporter
FJ654_RS17325	COG0477	Major facilitator Superfamily
FJ654_RS17335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJ654_RS17365	COG4585	Histidine kinase
FJ654_RS17375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FJ654_RS17380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FJ654_RS17385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FJ654_RS17390	COG0193	aminoacyl-tRNA hydrolase activity
FJ654_RS17405	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FJ654_RS17415	COG1309	transcriptional regulator
FJ654_RS17445	COG4106	trans-aconitate 2-methyltransferase activity
FJ654_RS17455	COG2197	response regulator
FJ654_RS17470	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FJ654_RS17505	COG0488	(ABC) transporter
FJ654_RS17510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FJ654_RS17515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FJ654_RS17520	COG3584	3D domain protein
FJ654_RS17520	COG3583	domain protein
FJ654_RS17525	COG0084	hydrolase, TatD family'
FJ654_RS17560	COG0310	cobalt ion transport
FJ654_RS17570	COG1122	ATPase activity
FJ654_RS17575	COG1846	Transcriptional regulator
FJ654_RS17580	COG1764	response to oxidative stress
FJ654_RS17585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJ654_RS17600	COG0442	prolyl-tRNA aminoacylation
FJ654_RS17605	COG0456	acetyltransferase
FJ654_RS17615	COG0793	Belongs to the peptidase S41A family
FJ654_RS17615	COG4946	Tricorn protease homolog
FJ654_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS17630	COG2267	carboxylic ester hydrolase activity
FJ654_RS17635	COG2072	flavoprotein involved in K transport
FJ654_RS17650	COG0708	Exodeoxyribonuclease III
FJ654_RS17675	COG0315	cyclic pyranopterin monophosphate synthase activity
FJ654_RS17675	COG0521	Mo-molybdopterin cofactor biosynthetic process
FJ654_RS17680	COG0315	cyclic pyranopterin monophosphate synthase activity
FJ654_RS17690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FJ654_RS17695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FJ654_RS17710	COG0477	Major facilitator Superfamily
FJ654_RS17720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FJ654_RS17730	COG1970	mechanosensitive ion channel activity
FJ654_RS17745	COG3191	aminopeptidase activity
FJ654_RS17755	COG1376	ErfK ybiS ycfS ynhG family protein
FJ654_RS17770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FJ654_RS17770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FJ654_RS17780	COG1349	DNA-binding transcription factor activity
FJ654_RS17785	COG0477	Major facilitator Superfamily
FJ654_RS17815	COG1247	-acetyltransferase
FJ654_RS17820	COG3384	dioxygenase
FJ654_RS17825	COG1846	Transcriptional regulator
FJ654_RS17845	COG1414	Transcriptional regulator
FJ654_RS17860	COG3973	AAA domain
FJ654_RS17905	COG0386	Belongs to the glutathione peroxidase family
FJ654_RS17925	COG1686	Belongs to the peptidase S11 family
FJ654_RS17940	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS17975	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJ654_RS17985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS18045	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS18075	COG2197	response regulator
FJ654_RS18090	COG3903	Transcriptional regulator
FJ654_RS18090	COG3629	intracellular signal transduction
FJ654_RS18105	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS18120	COG1024	Enoyl-CoA hydratase
FJ654_RS18125	COG0596	Alpha beta hydrolase
FJ654_RS18135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJ654_RS18135	COG0515	serine threonine protein kinase
FJ654_RS18145	COG1309	transcriptional regulator
FJ654_RS18155	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS18165	COG0259	pyridoxamine-phosphate oxidase activity
FJ654_RS18175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FJ654_RS18190	COG2072	flavoprotein involved in K transport
FJ654_RS18195	COG1231	oxidoreductase activity
FJ654_RS18205	COG1024	Enoyl-CoA hydratase
FJ654_RS18235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FJ654_RS18240	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS18245	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS18265	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS18270	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS18275	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS18340	COG0596	Alpha beta hydrolase
FJ654_RS18340	COG2945	thiolester hydrolase activity
FJ654_RS18350	COG4821	SIS domain
FJ654_RS18370	COG0259	pyridoxamine-phosphate oxidase activity
FJ654_RS18390	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS18405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FJ654_RS18425	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FJ654_RS18440	COG0277	FAD linked oxidase domain protein
FJ654_RS18440	COG0247	lactate metabolic process
FJ654_RS18445	COG2815	serine threonine protein kinase
FJ654_RS18445	COG0515	serine threonine protein kinase
FJ654_RS18450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FJ654_RS18455	COG0596	Alpha beta hydrolase
FJ654_RS18465	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FJ654_RS18480	COG3321	synthase
FJ654_RS18480	COG0604	alcohol dehydrogenase
FJ654_RS18495	COG0667	Aldo Keto reductase
FJ654_RS18515	COG1846	Transcriptional regulator
FJ654_RS18525	COG2252	PERMEase
FJ654_RS18535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJ654_RS18570	COG2814	Major facilitator Superfamily
FJ654_RS18580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FJ654_RS18585	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FJ654_RS18595	COG1278	Cold shock
FJ654_RS18625	COG1061	Type III restriction enzyme res subunit
FJ654_RS18635	COG3973	AAA domain
FJ654_RS18665	COG1737	Transcriptional regulator
FJ654_RS18670	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FJ654_RS18680	COG4106	trans-aconitate 2-methyltransferase activity
FJ654_RS18695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FJ654_RS18705	COG0459	protein refolding
FJ654_RS18710	COG1278	Cold shock
FJ654_RS18725	COG0463	Glycosyl transferase, family 2
FJ654_RS18730	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FJ654_RS18760	COG1105	Belongs to the carbohydrate kinase PfkB family
FJ654_RS18770	COG5001	Diguanylate cyclase
FJ654_RS18770	COG3300	MHYT domain
FJ654_RS18785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FJ654_RS18835	COG0667	Aldo Keto reductase
FJ654_RS18840	COG0583	DNA-binding transcription factor activity
FJ654_RS18900	COG3842	ATPase activity
FJ654_RS18910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FJ654_RS18920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJ654_RS18925	COG0215	cysteine-tRNA ligase activity
FJ654_RS18930	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FJ654_RS18935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FJ654_RS18945	COG1329	Transcriptional regulator
FJ654_RS18990	COG0588	phosphoglycerate mutase activity
FJ654_RS19020	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS19070	COG2226	methyltransferase
FJ654_RS19090	COG3973	AAA domain
FJ654_RS19095	COG1309	transcriptional regulator
FJ654_RS19115	COG2188	Transcriptional regulator
FJ654_RS19125	COG2186	Transcriptional regulator
FJ654_RS19135	COG4552	Acetyltransferase involved in intracellular survival and related
FJ654_RS19145	COG1490	D-aminoacyl-tRNA deacylase activity
FJ654_RS19165	COG0735	belongs to the Fur family
FJ654_RS19170	COG3485	protocatechuate 3,4-dioxygenase
FJ654_RS19220	COG2897	thiosulfate sulfurtransferase activity
FJ654_RS19255	COG0745	RESPONSE REGULATOR receiver
FJ654_RS19260	COG1609	Transcriptional regulator
FJ654_RS19265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FJ654_RS19275	COG0745	RESPONSE REGULATOR receiver
FJ654_RS19320	COG0737	Belongs to the 5'-nucleotidase family
FJ654_RS19325	COG0456	acetyltransferase
FJ654_RS19345	COG1131	(ABC) transporter
FJ654_RS19360	COG1725	Transcriptional regulator
FJ654_RS19365	COG3842	ATPase activity
FJ654_RS19375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FJ654_RS19405	COG1937	Protein conserved in bacteria
FJ654_RS19415	COG0306	phosphate transporter
FJ654_RS19420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FJ654_RS19440	COG0277	FAD linked oxidase domain protein
FJ654_RS19445	COG0671	phosphoesterase, PA-phosphatase related
FJ654_RS19450	COG0739	heme binding
FJ654_RS19450	COG1196	nuclear chromosome segregation
FJ654_RS19450	COG0741	lytic transglycosylase activity
FJ654_RS19545	COG1252	NADH dehydrogenase
FJ654_RS19575	COG0579	oxidoreductase
FJ654_RS19580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FJ654_RS19590	COG0667	Aldo Keto reductase
FJ654_RS19615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FJ654_RS19625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJ654_RS19625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJ654_RS19645	COG0513	Belongs to the DEAD box helicase family
FJ654_RS19690	COG1643	Atp-dependent helicase
FJ654_RS19715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FJ654_RS19725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FJ654_RS19745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJ654_RS19750	COG0047	phosphoribosylformylglycinamidine synthase activity
FJ654_RS19755	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJ654_RS19790	COG2197	response regulator
FJ654_RS19800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FJ654_RS19815	COG0151	Belongs to the GarS family
FJ654_RS19880	COG1609	Transcriptional regulator
FJ654_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS19970	COG0433	COG0433 Predicted ATPase
FJ654_RS19985	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FJ654_RS20100	COG1191	sigma factor activity
FJ654_RS20105	COG1191	sigma factor activity
FJ654_RS20130	COG2353	YceI-like domain
FJ654_RS20135	COG3467	pyridoxamine 5'-phosphate
FJ654_RS20145	COG0477	Major facilitator Superfamily
FJ654_RS20150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FJ654_RS20160	COG2205	protein histidine kinase activity
FJ654_RS20165	COG0745	RESPONSE REGULATOR receiver
FJ654_RS20180	COG1846	Transcriptional regulator
FJ654_RS20240	COG1309	transcriptional regulator
FJ654_RS20245	COG2814	Major facilitator Superfamily
FJ654_RS20250	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS20255	COG1595	DNA-templated transcription, initiation
FJ654_RS20285	COG0641	radical SAM
FJ654_RS20295	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FJ654_RS20310	COG0006	proline dipeptidase activity
FJ654_RS20330	COG0653	protein targeting
FJ654_RS20350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FJ654_RS20400	COG2746	aminoglycoside 3-N-acetyltransferase activity
FJ654_RS20415	COG2267	carboxylic ester hydrolase activity
FJ654_RS20440	COG1999	signal sequence binding
FJ654_RS20455	COG2837	iron assimilation
FJ654_RS20465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FJ654_RS20470	COG0561	phosphatase activity
FJ654_RS20500	COG1131	(ABC) transporter
FJ654_RS20520	COG0789	Transcriptional regulator
FJ654_RS20525	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FJ654_RS20540	COG0561	phosphatase activity
FJ654_RS20545	COG1196	nuclear chromosome segregation
FJ654_RS20545	COG0741	lytic transglycosylase activity
FJ654_RS20545	COG0739	heme binding
FJ654_RS20550	COG4988	ABC transporter
FJ654_RS20555	COG1294	oxidase, subunit
FJ654_RS20560	COG1271	oxidase subunit
FJ654_RS20565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJ654_RS20570	COG1609	Transcriptional regulator
FJ654_RS20590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FJ654_RS20620	COG0662	Cupin 2, conserved barrel domain protein
FJ654_RS20625	COG1950	PFAM Membrane protein of
FJ654_RS20630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJ654_RS20635	COG0626	cystathionine gamma-synthase activity
FJ654_RS20665	COG2814	Major facilitator Superfamily
FJ654_RS20680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FJ654_RS20685	COG0305	Participates in initiation and elongation during chromosome replication
FJ654_RS20695	COG0359	binds to the 23S rRNA
FJ654_RS20700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FJ654_RS20705	COG0629	single-stranded DNA binding
FJ654_RS20710	COG0360	Binds together with S18 to 16S ribosomal RNA
FJ654_RS20735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FJ654_RS20745	COG1260	myo-inositol-1-phosphate synthase
FJ654_RS20755	COG0617	tRNA 3'-terminal CCA addition
FJ654_RS20770	COG0515	serine threonine protein kinase
FJ654_RS20770	COG2815	serine threonine protein kinase
FJ654_RS20775	COG1595	DNA-templated transcription, initiation
FJ654_RS20785	COG0492	ferredoxin-NADP+ reductase activity
FJ654_RS20790	COG3118	belongs to the thioredoxin family
FJ654_RS20805	COG1192	Involved in chromosome partitioning
FJ654_RS20810	COG0357	Ribosomal RNA small subunit methyltransferase G
FJ654_RS20820	COG0706	membrane insertase activity
FJ654_RS20825	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FJ654_RS20830	COG0594	ribonuclease P activity
FJ654_RS20845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FJ654_RS20855	COG0592	DNA-directed DNA polymerase activity
FJ654_RS20860	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FJ654_RS20865	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FJ654_RS20870	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FJ654_RS20875	COG0187	DNA topoisomerase II activity
FJ654_RS20880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FJ654_RS20945	COG0705	Rhomboid family
FJ654_RS20960	COG3764	Sortase (surface protein transpeptidase)
FJ654_RS20975	COG3764	Sortase (surface protein transpeptidase)
FJ654_RS20980	COG3764	Sortase (surface protein transpeptidase)
FJ654_RS20985	COG0515	serine threonine protein kinase
FJ654_RS20995	COG0768	penicillin binding
FJ654_RS21010	COG1716	ATPase activity
FJ654_RS21015	COG1716	ATPase activity
FJ654_RS21025	COG0577	efflux transmembrane transporter activity
FJ654_RS21030	COG1136	(ABC) transporter
FJ654_RS21085	COG1250	3-hydroxyacyl-CoA dehydrogenase
FJ654_RS21090	COG1309	transcriptional regulator
FJ654_RS21095	COG1522	sequence-specific DNA binding
FJ654_RS21140	COG0604	alcohol dehydrogenase
FJ654_RS21140	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS21140	COG3321	synthase
FJ654_RS21155	COG0515	serine threonine protein kinase
FJ654_RS21170	COG0022	dehydrogenase e1 component
FJ654_RS21175	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJ654_RS21195	COG2271	Major facilitator Superfamily
FJ654_RS21220	COG0662	Cupin 2, conserved barrel domain protein
FJ654_RS21235	COG1362	aminopeptidase activity
FJ654_RS21240	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS21260	COG1741	Belongs to the pirin family
FJ654_RS21275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FJ654_RS21315	COG0326	Molecular chaperone. Has ATPase activity
FJ654_RS21325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJ654_RS21340	COG0583	DNA-binding transcription factor activity
FJ654_RS21350	COG1289	transmembrane transporter activity
FJ654_RS21360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FJ654_RS21365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FJ654_RS21435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FJ654_RS21440	COG1957	nucleoside hydrolase
FJ654_RS21445	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FJ654_RS21450	COG0640	Transcriptional regulator
FJ654_RS21470	COG0366	Alpha amylase catalytic
FJ654_RS21505	COG4213	ABC transporter substrate-binding protein
FJ654_RS21510	COG4585	Histidine kinase
FJ654_RS21515	COG2197	response regulator
FJ654_RS21530	COG1595	DNA-templated transcription, initiation
FJ654_RS21545	COG0135	phosphoribosylanthranilate isomerase activity
FJ654_RS21560	COG2409	Drug exporters of the RND superfamily
FJ654_RS21565	COG4585	Histidine kinase
FJ654_RS21585	COG3387	PFAM Glycoside hydrolase 15-related
FJ654_RS21605	COG2755	lipolytic protein G-D-S-L family
FJ654_RS21605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FJ654_RS21655	COG0513	Belongs to the DEAD box helicase family
FJ654_RS21660	COG1278	Cold shock
FJ654_RS21710	COG2867	negative regulation of translational initiation
FJ654_RS21715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJ654_RS21720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS21730	COG0662	Cupin 2, conserved barrel domain protein
FJ654_RS21750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS21785	COG1595	DNA-templated transcription, initiation
FJ654_RS21800	COG0300	oxidoreductase activity
FJ654_RS21830	COG1309	transcriptional regulator
FJ654_RS21845	COG0717	Belongs to the dCTP deaminase family
FJ654_RS21850	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FJ654_RS21880	COG0247	lactate metabolic process
FJ654_RS21880	COG2181	nitrate reductase activity
FJ654_RS21885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FJ654_RS21890	COG0443	Heat shock 70 kDa protein
FJ654_RS21895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FJ654_RS21900	COG0484	heat shock protein binding
FJ654_RS21905	COG0789	Transcriptional regulator
FJ654_RS21920	COG4213	ABC transporter substrate-binding protein
FJ654_RS21925	COG1305	Transglutaminase-like
FJ654_RS21975	COG0542	response to heat
FJ654_RS22025	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FJ654_RS22040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FJ654_RS22045	COG0191	fructose-bisphosphate aldolase activity
FJ654_RS22050	COG0477	Major facilitator Superfamily
FJ654_RS22065	COG3844	kynureninase activity
FJ654_RS22085	COG4585	Histidine kinase
FJ654_RS22090	COG2197	response regulator
FJ654_RS22095	COG4585	Histidine kinase
FJ654_RS22100	COG2197	response regulator
FJ654_RS22140	COG3559	Exporter of polyketide antibiotics
FJ654_RS22145	COG1131	(ABC) transporter
FJ654_RS22160	COG4303	Ethanolamine ammonia lyase large subunit
FJ654_RS22175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FJ654_RS22185	COG0737	Belongs to the 5'-nucleotidase family
FJ654_RS22220	COG1802	Transcriptional regulator
FJ654_RS22225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FJ654_RS22240	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FJ654_RS22245	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FJ654_RS22315	COG0701	Predicted permease
FJ654_RS22335	COG4249	Peptidase C14 caspase catalytic subunit p20
FJ654_RS22335	COG2319	Wd-40 repeat
FJ654_RS22340	COG0640	Transcriptional regulator
FJ654_RS22350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJ654_RS22370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJ654_RS22375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS22380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS22410	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS22415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS22420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJ654_RS22425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FJ654_RS22430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FJ654_RS22435	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS22445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FJ654_RS22450	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS22475	COG2409	Drug exporters of the RND superfamily
FJ654_RS22480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FJ654_RS22505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FJ654_RS22525	COG2091	lysine biosynthetic process via aminoadipic acid
FJ654_RS22555	COG0586	Pfam SNARE associated Golgi protein
FJ654_RS22670	COG0515	serine threonine protein kinase
FJ654_RS22670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJ654_RS22730	COG2188	Transcriptional regulator
FJ654_RS22750	COG1674	ftsk spoiiie
FJ654_RS22810	COG1408	metallophosphoesterase
FJ654_RS22840	COG0003	Pfam Anion-transporting ATPase
FJ654_RS22900	COG2267	carboxylic ester hydrolase activity
FJ654_RS22910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FJ654_RS22915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJ654_RS22990	COG1111	helicase
FJ654_RS22990	COG1205	dead DEAH box helicase
FJ654_RS22995	COG1366	Belongs to the anti-sigma-factor antagonist family
FJ654_RS23000	COG2172	sigma factor antagonist activity
FJ654_RS23005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FJ654_RS23025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FJ654_RS23025	COG1754	DNA topoisomerase type I activity
FJ654_RS23030	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FJ654_RS23125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FJ654_RS23130	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FJ654_RS23160	COG0673	inositol 2-dehydrogenase activity
FJ654_RS23170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS23220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FJ654_RS23235	COG3629	intracellular signal transduction
FJ654_RS23235	COG3903	Transcriptional regulator
FJ654_RS23265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJ654_RS23270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS23270	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS23275	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS23275	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS23295	COG3903	Transcriptional regulator
FJ654_RS23295	COG3629	intracellular signal transduction
FJ654_RS23300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJ654_RS23300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJ654_RS23325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FJ654_RS23330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FJ654_RS23335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FJ654_RS23340	COG0254	rRNA binding
FJ654_RS23350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FJ654_RS23370	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS23375	COG2318	DinB family
FJ654_RS23395	COG0076	glutamate decarboxylase activity
FJ654_RS23405	COG0789	Transcriptional regulator
FJ654_RS23410	COG0393	Putative heavy-metal-binding
FJ654_RS23415	COG0586	Pfam SNARE associated Golgi protein
FJ654_RS23425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FJ654_RS23430	COG2027	D-alanyl-D-alanine carboxypeptidase
FJ654_RS23440	COG0037	tRNA processing
FJ654_RS23455	COG0302	gtp cyclohydrolase
FJ654_RS23470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FJ654_RS23485	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FJ654_RS23485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FJ654_RS23510	COG0649	NAD binding
FJ654_RS23525	COG2197	response regulator
FJ654_RS23540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FJ654_RS23545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FJ654_RS23555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FJ654_RS23570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FJ654_RS23610	COG0739	heme binding
FJ654_RS23620	COG0477	Major facilitator Superfamily
FJ654_RS23625	COG2205	protein histidine kinase activity
FJ654_RS23630	COG0745	RESPONSE REGULATOR receiver
FJ654_RS23640	COG1595	DNA-templated transcription, initiation
FJ654_RS23645	COG1194	a g-specific adenine glycosylase
FJ654_RS23655	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FJ654_RS23675	COG0248	Ppx GppA phosphatase
FJ654_RS23680	COG1082	Xylose isomerase domain protein TIM barrel
FJ654_RS23685	COG1309	transcriptional regulator
FJ654_RS23690	COG0129	dihydroxy-acid dehydratase activity
FJ654_RS23705	COG4991	sh3 domain protein
FJ654_RS23720	COG1129	ABC transporter
FJ654_RS23720	COG0842	Transport permease protein
FJ654_RS23730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FJ654_RS23735	COG0180	Tryptophanyl-tRNA synthetase
FJ654_RS23770	COG0738	Major facilitator superfamily
FJ654_RS23775	COG0123	including yeast histone deacetylase and acetoin utilization protein
FJ654_RS23825	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FJ654_RS23830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FJ654_RS23835	COG0181	hydroxymethylbilane synthase activity
FJ654_RS23840	COG1648	precorrin-2 dehydrogenase activity
FJ654_RS23840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FJ654_RS23845	COG0113	porphobilinogen synthase activity
FJ654_RS23850	COG3152	Membrane
FJ654_RS23860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FJ654_RS23865	COG0569	domain protein
FJ654_RS23870	COG0483	inositol monophosphate 1-phosphatase activity
FJ654_RS23910	COG0018	arginyl-trna synthetase
FJ654_RS23915	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FJ654_RS23935	COG1690	Belongs to the RtcB family
FJ654_RS23950	COG1742	UPF0060 membrane protein
FJ654_RS23960	COG1733	regulation of RNA biosynthetic process
FJ654_RS23965	COG0604	alcohol dehydrogenase
FJ654_RS23970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS23985	COG2205	protein histidine kinase activity
FJ654_RS24000	COG0477	Major facilitator Superfamily
FJ654_RS24025	COG0513	Belongs to the DEAD box helicase family
FJ654_RS24030	COG1278	Cold shock
FJ654_RS24065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FJ654_RS24070	COG0406	alpha-ribazole phosphatase activity
FJ654_RS24080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FJ654_RS24085	COG0785	Cytochrome C biogenesis protein
FJ654_RS24090	COG1333	cytochrome c biogenesis protein
FJ654_RS24095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FJ654_RS24135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FJ654_RS24145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FJ654_RS24155	COG0163	prenyltransferase activity
FJ654_RS24165	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJ654_RS24170	COG1573	uracil-dna glycosylase
FJ654_RS24185	COG1309	transcriptional regulator
FJ654_RS24200	COG0183	Belongs to the thiolase family
FJ654_RS24240	COG2124	cytochrome p450
FJ654_RS24245	COG0456	acetyltransferase
FJ654_RS24250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FJ654_RS24265	COG1607	acyl-coa hydrolase
FJ654_RS24270	COG0019	diaminopimelate decarboxylase activity
FJ654_RS24300	COG1053	succinate dehydrogenase
FJ654_RS24305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FJ654_RS24310	COG1278	Cold shock
FJ654_RS24315	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FJ654_RS24320	COG0515	serine threonine protein kinase
FJ654_RS24320	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJ654_RS24330	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJ654_RS24340	COG3979	chitinase
FJ654_RS24360	COG2226	methyltransferase
FJ654_RS24380	COG0242	peptide deformylase activity
FJ654_RS24395	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJ654_RS24400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJ654_RS24405	COG0649	NAD binding
FJ654_RS24415	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FJ654_RS24420	COG1034	ATP synthesis coupled electron transport
FJ654_RS24425	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FJ654_RS24430	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJ654_RS24440	COG0713	ATP synthesis coupled electron transport
FJ654_RS24445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FJ654_RS24455	COG1007	ATP synthesis coupled electron transport
FJ654_RS24465	COG0514	ATP-dependent DNA helicase (RecQ)
FJ654_RS24470	COG0657	acetylesterase activity
FJ654_RS24485	COG0300	oxidoreductase activity
FJ654_RS24490	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FJ654_RS24500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJ654_RS24515	COG2188	Transcriptional regulator
FJ654_RS24555	COG1175	transmembrane transport
FJ654_RS24560	COG0395	ABC-type sugar transport system, permease component
FJ654_RS24570	COG0561	phosphatase activity
FJ654_RS24585	COG0142	geranyltranstransferase activity
FJ654_RS24605	COG0655	NAD(P)H dehydrogenase (quinone) activity
FJ654_RS24635	COG0702	epimerase
FJ654_RS24640	COG1733	regulation of RNA biosynthetic process
FJ654_RS24645	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJ654_RS24650	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJ654_RS24650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJ654_RS24670	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJ654_RS24675	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJ654_RS24680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJ654_RS24685	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FJ654_RS24700	COG0713	ATP synthesis coupled electron transport
FJ654_RS24715	COG1007	ATP synthesis coupled electron transport
FJ654_RS24720	COG0501	Belongs to the peptidase M48B family
FJ654_RS24725	COG3304	Inner membrane component domain
FJ654_RS24740	COG2261	transglycosylase associated protein
FJ654_RS24745	COG1666	GTP binding
FJ654_RS24785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FJ654_RS24790	COG2030	dehydratase
FJ654_RS24805	COG0477	Major facilitator Superfamily
FJ654_RS24815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FJ654_RS24825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FJ654_RS24830	COG0436	Aminotransferase
FJ654_RS24845	COG0250	Participates in transcription elongation, termination and antitermination
FJ654_RS24865	COG0081	regulation of translation
FJ654_RS24880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FJ654_RS24885	COG0222	ribosome binding
FJ654_RS24895	COG0085	RNA polymerase activity
FJ654_RS24900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FJ654_RS24910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FJ654_RS24915	COG0049	tRNA binding
FJ654_RS24920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FJ654_RS24925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FJ654_RS24930	COG2755	lipolytic protein G-D-S-L family
FJ654_RS24930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FJ654_RS24940	COG0051	transcription antitermination factor activity, RNA binding
FJ654_RS24945	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FJ654_RS24950	COG0088	Forms part of the polypeptide exit tunnel
FJ654_RS24955	COG0089	rRNA binding
FJ654_RS24960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FJ654_RS24965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FJ654_RS24970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FJ654_RS24975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FJ654_RS24980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FJ654_RS24985	COG0255	Belongs to the universal ribosomal protein uL29 family
FJ654_RS24990	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FJ654_RS24995	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FJ654_RS25000	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FJ654_RS25005	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FJ654_RS25010	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FJ654_RS25020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FJ654_RS25025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FJ654_RS25030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FJ654_RS25035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FJ654_RS25040	COG1841	ribosomal large subunit assembly
FJ654_RS25045	COG0200	Binds to the 23S rRNA
FJ654_RS25055	COG0563	adenylate kinase activity
FJ654_RS25065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FJ654_RS25070	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FJ654_RS25075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FJ654_RS25080	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FJ654_RS25085	COG0202	RNA polymerase activity
FJ654_RS25090	COG0203	ribosomal protein L17
FJ654_RS25095	COG0101	tRNA pseudouridine synthase activity
FJ654_RS25105	COG1215	transferase activity, transferring glycosyl groups
FJ654_RS25140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FJ654_RS25145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FJ654_RS25150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJ654_RS25160	COG1072	(Pantothenic acid kinase))
FJ654_RS25170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJ654_RS25200	COG0736	holo-[acyl-carrier-protein] synthase activity
FJ654_RS25220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FJ654_RS25230	COG0802	atpase or kinase
FJ654_RS25250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FJ654_RS25265	COG1609	Transcriptional regulator
FJ654_RS25285	COG4941	Belongs to the sigma-70 factor family
FJ654_RS25300	COG0726	polysaccharide deacetylase
FJ654_RS25305	COG0726	polysaccharide deacetylase
FJ654_RS25310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FJ654_RS25315	COG0459	protein refolding
FJ654_RS25325	COG4221	oxidoreductase activity
FJ654_RS25330	COG0583	DNA-binding transcription factor activity
FJ654_RS25345	COG1595	DNA-templated transcription, initiation
FJ654_RS25355	COG0516	GMP reductase activity
FJ654_RS25370	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FJ654_RS25385	COG0515	serine threonine protein kinase
FJ654_RS25385	COG2815	serine threonine protein kinase
FJ654_RS25390	COG0515	serine threonine protein kinase
FJ654_RS25395	COG0515	serine threonine protein kinase
FJ654_RS25400	COG0515	serine threonine protein kinase
FJ654_RS25405	COG0515	serine threonine protein kinase
FJ654_RS25410	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS25435	COG0519	Catalyzes the synthesis of GMP from XMP
FJ654_RS25435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FJ654_RS25485	COG2197	response regulator
FJ654_RS25515	COG0739	heme binding
FJ654_RS25525	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS25525	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS25540	COG0714	Associated with various cellular activities
FJ654_RS25545	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FJ654_RS25555	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FJ654_RS25565	COG0045	succinate-CoA ligase (ADP-forming) activity
FJ654_RS25595	COG0138	bifunctional purine biosynthesis protein purh
FJ654_RS25610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FJ654_RS25640	COG0039	L-malate dehydrogenase activity
FJ654_RS25650	COG0477	Major facilitator Superfamily
FJ654_RS25685	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS25695	COG4175	Glycine betaine
FJ654_RS25695	COG0517	IMP dehydrogenase activity
FJ654_RS25715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FJ654_RS25720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FJ654_RS25725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FJ654_RS25740	COG0754	glutathionylspermidine amidase activity
FJ654_RS25750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FJ654_RS25770	COG0180	Tryptophanyl-tRNA synthetase
FJ654_RS25790	COG0671	phosphoesterase, PA-phosphatase related
FJ654_RS25800	COG1295	ribonuclease BN
FJ654_RS25805	COG1686	Belongs to the peptidase S11 family
FJ654_RS25810	COG1408	metallophosphoesterase
FJ654_RS25825	COG2205	protein histidine kinase activity
FJ654_RS25830	COG0745	RESPONSE REGULATOR receiver
FJ654_RS25835	COG2409	Drug exporters of the RND superfamily
FJ654_RS25895	COG1053	succinate dehydrogenase
FJ654_RS25905	COG2009	succinate dehydrogenase
FJ654_RS25915	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FJ654_RS25985	COG1595	DNA-templated transcription, initiation
FJ654_RS26000	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS26000	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS26025	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FJ654_RS26035	COG1216	Glycosyl transferase, family 2
FJ654_RS26050	COG2089	acid synthase
FJ654_RS26080	COG2226	methyltransferase
FJ654_RS26100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FJ654_RS26100	COG1473	amidohydrolase
FJ654_RS26105	COG1744	ABC transporter substrate-binding protein PnrA-like
FJ654_RS26110	COG3845	ABC transporter
FJ654_RS26115	COG4603	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS26120	COG1079	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS26150	COG2814	Major facilitator Superfamily
FJ654_RS26155	COG0583	DNA-binding transcription factor activity
FJ654_RS26165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FJ654_RS26190	COG2205	protein histidine kinase activity
FJ654_RS26195	COG0745	RESPONSE REGULATOR receiver
FJ654_RS26200	COG1595	DNA-templated transcription, initiation
FJ654_RS26215	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS26220	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS26245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJ654_RS26270	COG4770	biotin carboxylase activity
FJ654_RS26280	COG0424	maF-like protein
FJ654_RS26290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FJ654_RS26300	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FJ654_RS26310	COG1024	Enoyl-CoA hydratase
FJ654_RS26325	COG2986	histidine ammonia-lyase
FJ654_RS26350	COG1404	Belongs to the peptidase S8 family
FJ654_RS26360	COG1136	(ABC) transporter
FJ654_RS26365	COG1404	Belongs to the peptidase S8 family
FJ654_RS26380	COG1064	alcohol dehydrogenase
FJ654_RS26395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJ654_RS26470	COG2186	Transcriptional regulator
FJ654_RS26530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJ654_RS26555	COG2255	four-way junction helicase activity
FJ654_RS26560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FJ654_RS26575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FJ654_RS26585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FJ654_RS26595	COG2255	four-way junction helicase activity
FJ654_RS26600	COG1331	Highly conserved protein containing a thioredoxin domain
FJ654_RS26610	COG1309	transcriptional regulator
FJ654_RS26615	COG0477	Major facilitator Superfamily
FJ654_RS26625	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FJ654_RS26645	COG0436	Aminotransferase
FJ654_RS26660	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FJ654_RS26670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS26675	COG1414	Transcriptional regulator
FJ654_RS26680	COG0251	oxidation-reduction process
FJ654_RS26720	COG2894	cell division
FJ654_RS26750	COG4585	Histidine kinase
FJ654_RS26755	COG2197	response regulator
FJ654_RS26800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FJ654_RS26805	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FJ654_RS26810	COG0741	lytic transglycosylase activity
FJ654_RS26845	COG1136	(ABC) transporter
FJ654_RS26865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FJ654_RS26880	COG0114	fumarate hydratase activity
FJ654_RS26905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FJ654_RS26905	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FJ654_RS26930	COG0778	Nitroreductase
FJ654_RS26935	COG1722	exodeoxyribonuclease VII activity
FJ654_RS26940	COG1570	exodeoxyribonuclease VII activity
FJ654_RS26950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FJ654_RS26965	COG0012	GTP binding
FJ654_RS26970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FJ654_RS26975	COG0583	DNA-binding transcription factor activity
FJ654_RS27030	COG1053	succinate dehydrogenase
FJ654_RS27050	COG1217	gtp-binding protein TYPA
FJ654_RS27055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJ654_RS27060	COG4166	transmembrane transport
FJ654_RS27065	COG0601	transmembrane transport
FJ654_RS27075	COG4608	Belongs to the ABC transporter superfamily
FJ654_RS27085	COG0601	transmembrane transport
FJ654_RS27090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJ654_RS27095	COG0444	Belongs to the ABC transporter superfamily
FJ654_RS27100	COG4608	Belongs to the ABC transporter superfamily
FJ654_RS27115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FJ654_RS27130	COG1131	(ABC) transporter
FJ654_RS27140	COG4585	Histidine kinase
FJ654_RS27145	COG2197	response regulator
FJ654_RS27155	COG0456	acetyltransferase
FJ654_RS27180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FJ654_RS27190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FJ654_RS27200	COG2818	Glycosylase
FJ654_RS27205	COG1024	Enoyl-CoA hydratase
FJ654_RS27220	COG1595	DNA-templated transcription, initiation
FJ654_RS27230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FJ654_RS27235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJ654_RS27275	COG0598	Magnesium transport protein CorA
FJ654_RS27285	COG2814	Major facilitator Superfamily
FJ654_RS27300	COG2095	MarC family integral membrane protein
FJ654_RS27310	COG1432	Conserved Protein
FJ654_RS27320	COG0513	Belongs to the DEAD box helicase family
FJ654_RS27365	COG0747	negative chemotaxis
FJ654_RS27370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJ654_RS27435	COG0210	DNA helicase
FJ654_RS27445	COG2816	NAD+ diphosphatase activity
FJ654_RS27480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FJ654_RS27530	COG3480	Lon protease (S16) C-terminal proteolytic domain
FJ654_RS27540	COG1615	UPF0182 protein
FJ654_RS27570	COG0483	inositol monophosphate 1-phosphatase activity
FJ654_RS27585	COG1162	GTPase activity
FJ654_RS27590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FJ654_RS27600	COG2135	peptidase activity
FJ654_RS27610	COG1595	DNA-templated transcription, initiation
FJ654_RS27615	COG5662	AntiSigma factor
FJ654_RS27645	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJ654_RS27645	COG2199	diguanylate cyclase activity
FJ654_RS27660	COG0242	peptide deformylase activity
FJ654_RS27670	COG2124	cytochrome p450
FJ654_RS27695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJ654_RS27720	COG2188	Transcriptional regulator
FJ654_RS27725	COG2182	Extracellular solute-binding protein
FJ654_RS27730	COG1175	transmembrane transport
FJ654_RS27735	COG0395	ABC-type sugar transport system, permease component
FJ654_RS27740	COG1472	Belongs to the glycosyl hydrolase 3 family
FJ654_RS27745	COG0363	glucosamine-6-phosphate deaminase activity
FJ654_RS27750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJ654_RS27765	COG1597	lipid kinase activity
FJ654_RS27795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FJ654_RS27805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FJ654_RS27810	COG0142	geranyltranstransferase activity
FJ654_RS27815	COG0456	acetyltransferase
FJ654_RS27830	COG4941	Belongs to the sigma-70 factor family
FJ654_RS27865	COG2326	polyphosphate kinase activity
FJ654_RS27885	COG4106	trans-aconitate 2-methyltransferase activity
FJ654_RS27890	COG1126	abc transporter atp-binding protein
FJ654_RS27910	COG0281	malic enzyme
FJ654_RS27915	COG0604	alcohol dehydrogenase
FJ654_RS27945	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJ654_RS27945	COG0567	Dehydrogenase, E1 component
FJ654_RS27950	COG2205	protein histidine kinase activity
FJ654_RS27955	COG0745	RESPONSE REGULATOR receiver
FJ654_RS27980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FJ654_RS28025	COG0791	NLP P60 protein
FJ654_RS28060	COG0768	penicillin binding
FJ654_RS28075	COG2205	protein histidine kinase activity
FJ654_RS28095	COG3285	dna ligase
FJ654_RS28095	COG1793	dna ligase
FJ654_RS28100	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FJ654_RS28115	COG1595	DNA-templated transcription, initiation
FJ654_RS28120	COG3594	Acyltransferase
FJ654_RS28150	COG1404	Belongs to the peptidase S8 family
FJ654_RS28160	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS28175	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FJ654_RS28275	COG0018	arginyl-trna synthetase
FJ654_RS28280	COG0019	diaminopimelate decarboxylase activity
FJ654_RS28285	COG0460	homoserine dehydrogenase
FJ654_RS28290	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FJ654_RS28295	COG0083	homoserine kinase activity
FJ654_RS28315	COG0254	rRNA binding
FJ654_RS28320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FJ654_RS28325	COG2890	protein-(glutamine-N5) methyltransferase activity
FJ654_RS28335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJ654_RS28340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FJ654_RS28360	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJ654_RS28365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FJ654_RS28370	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJ654_RS28375	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FJ654_RS28380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FJ654_RS28385	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FJ654_RS28390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FJ654_RS28420	COG1250	3-hydroxyacyl-CoA dehydrogenase
FJ654_RS28435	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FJ654_RS28470	COG1131	(ABC) transporter
FJ654_RS28485	COG0346	lactoylglutathione lyase activity
FJ654_RS28490	COG0183	Belongs to the thiolase family
FJ654_RS28510	COG0745	RESPONSE REGULATOR receiver
FJ654_RS28610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FJ654_RS28615	COG0280	phosphate acetyltransferase
FJ654_RS28615	COG0857	belongs to the CobB CobQ family
FJ654_RS28620	COG0205	6-phosphofructokinase activity
FJ654_RS28635	COG4565	transcriptional regulatory protein
FJ654_RS28640	COG3290	protein histidine kinase activity
FJ654_RS28660	COG1846	Transcriptional regulator
FJ654_RS28690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FJ654_RS28695	COG3281	Trehalose synthase
FJ654_RS28700	COG0366	Alpha amylase catalytic
FJ654_RS28705	COG0366	Alpha amylase catalytic
FJ654_RS28715	COG0058	SHG alpha-glucan phosphorylase activity
FJ654_RS28735	COG1132	(ABC) transporter
FJ654_RS28740	COG1132	(ABC) transporter
FJ654_RS28745	COG1132	(ABC) transporter
FJ654_RS28750	COG1132	(ABC) transporter
FJ654_RS28755	COG1131	(ABC) transporter
FJ654_RS28765	COG4585	Histidine kinase
FJ654_RS28770	COG2197	response regulator
FJ654_RS28845	COG2160	L-arabinose isomerase activity
FJ654_RS28850	COG0235	Class ii aldolase
FJ654_RS28865	COG1349	DNA-binding transcription factor activity
FJ654_RS28880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FJ654_RS28885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FJ654_RS28900	COG1295	ribonuclease BN
FJ654_RS28935	COG1595	DNA-templated transcription, initiation
FJ654_RS28955	COG1595	DNA-templated transcription, initiation
FJ654_RS28960	COG1760	l-serine dehydratase
FJ654_RS28965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FJ654_RS28970	COG0509	glycine decarboxylation via glycine cleavage system
FJ654_RS28975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FJ654_RS28995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJ654_RS29000	COG0747	negative chemotaxis
FJ654_RS29010	COG0444	Belongs to the ABC transporter superfamily
FJ654_RS29015	COG4608	Belongs to the ABC transporter superfamily
FJ654_RS29025	COG2860	membrane
FJ654_RS29040	COG2378	regulation of single-species biofilm formation
FJ654_RS29065	COG0482	sulfurtransferase activity
FJ654_RS29075	COG4124	Belongs to the glycosyl hydrolase 26 family
FJ654_RS29075	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FJ654_RS29100	COG4221	oxidoreductase activity
FJ654_RS29110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FJ654_RS29120	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FJ654_RS29125	COG0154	amidase activity
FJ654_RS29135	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FJ654_RS29150	COG2409	Drug exporters of the RND superfamily
FJ654_RS29155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FJ654_RS29170	COG1672	PFAM Archaeal ATPase
FJ654_RS29170	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FJ654_RS29180	COG2133	pyrroloquinoline quinone binding
FJ654_RS29185	COG0667	Aldo Keto reductase
FJ654_RS29195	COG3300	MHYT domain
FJ654_RS29195	COG5001	Diguanylate cyclase
FJ654_RS29205	COG0440	acetolactate synthase activity
FJ654_RS29210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FJ654_RS29215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FJ654_RS29220	COG0477	Major facilitator Superfamily
FJ654_RS29235	COG0506	proline dehydrogenase activity
FJ654_RS29240	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS29245	COG2130	NADP-dependent
FJ654_RS29250	COG0583	DNA-binding transcription factor activity
FJ654_RS29265	COG0473	3-isopropylmalate dehydrogenase activity
FJ654_RS29270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FJ654_RS29275	COG0832	Belongs to the urease beta subunit family
FJ654_RS29275	COG0831	urea catabolic process
FJ654_RS29280	COG0804	urea catabolic process
FJ654_RS29285	COG2957	Belongs to the agmatine deiminase family
FJ654_RS29300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJ654_RS29310	COG1472	Belongs to the glycosyl hydrolase 3 family
FJ654_RS29340	COG5492	domain, Protein
FJ654_RS29345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FJ654_RS29365	COG2018	Roadblock/LC7 domain
FJ654_RS29385	COG2018	Roadblock/LC7 domain
FJ654_RS29390	COG5002	protein histidine kinase activity
FJ654_RS29410	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS29415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJ654_RS29455	COG1414	Transcriptional regulator
FJ654_RS29460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FJ654_RS29465	COG0066	3-isopropylmalate dehydratase activity
FJ654_RS29475	COG0776	regulation of translation
FJ654_RS29485	COG1920	GTP binding
FJ654_RS29495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FJ654_RS29500	COG1181	Belongs to the D-alanine--D-alanine ligase family
FJ654_RS29520	COG0351	phosphomethylpyrimidine kinase
FJ654_RS29525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FJ654_RS29530	COG1461	Dihydroxyacetone kinase
FJ654_RS29540	COG0326	Molecular chaperone. Has ATPase activity
FJ654_RS29550	COG0742	ribosomal rna small subunit methyltransferase
FJ654_RS29555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FJ654_RS29570	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FJ654_RS29575	COG0571	ribonuclease III activity
FJ654_RS29580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FJ654_RS29585	COG1733	regulation of RNA biosynthetic process
FJ654_RS29590	COG2340	Cysteine-rich secretory protein family
FJ654_RS29595	COG1254	Belongs to the acylphosphatase family
FJ654_RS29615	COG0477	Major facilitator Superfamily
FJ654_RS29650	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FJ654_RS29665	COG0442	prolyl-tRNA aminoacylation
FJ654_RS29675	COG0228	four-way junction DNA binding
FJ654_RS29680	COG1837	Belongs to the UPF0109 family
FJ654_RS29685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FJ654_RS29690	COG0336	Belongs to the RNA methyltransferase TrmD family
FJ654_RS29695	COG0335	large ribosomal subunit rRNA binding
FJ654_RS29710	COG0681	Belongs to the peptidase S26 family
FJ654_RS29730	COG0792	nuclease activity
FJ654_RS29745	COG1191	sigma factor activity
FJ654_RS29760	COG0052	Belongs to the universal ribosomal protein uS2 family
FJ654_RS29765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FJ654_RS29770	COG0528	UMP kinase activity
FJ654_RS29775	COG0233	cytoplasmic translational termination
FJ654_RS29780	COG0575	Belongs to the CDS family
FJ654_RS29820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FJ654_RS29830	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FJ654_RS29835	COG3842	ATPase activity
FJ654_RS29870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FJ654_RS29880	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS29900	COG0584	glycerophosphoryl diester phosphodiesterase
FJ654_RS29905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FJ654_RS29930	COG3842	ATPase activity
FJ654_RS29940	COG1177	transmembrane transport
FJ654_RS29945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FJ654_RS29970	COG2508	Transcriptional regulator
FJ654_RS29975	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS29995	COG4209	transmembrane transport
FJ654_RS30000	COG0395	ABC-type sugar transport system, permease component
FJ654_RS30020	COG1605	Chorismate mutase
FJ654_RS30040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FJ654_RS30045	COG0750	zinc metalloprotease
FJ654_RS30055	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FJ654_RS30075	COG0442	prolyl-tRNA aminoacylation
FJ654_RS30095	COG0779	Required for maturation of 30S ribosomal subunits
FJ654_RS30110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FJ654_RS30120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FJ654_RS30125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FJ654_RS30140	COG0455	bacterial-type flagellum organization
FJ654_RS30175	COG1404	Belongs to the peptidase S8 family
FJ654_RS30190	COG1404	Belongs to the peptidase S8 family
FJ654_RS30320	COG1674	ftsk spoiiie
FJ654_RS30330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FJ654_RS30335	COG1185	polyribonucleotide nucleotidyltransferase activity
FJ654_RS30340	COG0612	Peptidase, M16
FJ654_RS30345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FJ654_RS30365	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FJ654_RS30370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJ654_RS30375	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FJ654_RS30410	COG2208	phosphoserine phosphatase activity
FJ654_RS30410	COG2770	Histidine kinase
FJ654_RS30420	COG0784	Response regulator, receiver
FJ654_RS30420	COG2205	protein histidine kinase activity
FJ654_RS30430	COG1674	ftsk spoiiie
FJ654_RS30440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJ654_RS30450	COG1546	Belongs to the CinA family
FJ654_RS30450	COG1058	Belongs to the CinA family
FJ654_RS30455	COG1396	sequence-specific DNA binding
FJ654_RS30465	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS30470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FJ654_RS30475	COG1201	RNA secondary structure unwinding
FJ654_RS30515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FJ654_RS30540	COG0765	amino acid transport
FJ654_RS30545	COG0765	amino acid transport
FJ654_RS30550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJ654_RS30555	COG1126	abc transporter atp-binding protein
FJ654_RS30560	COG0745	RESPONSE REGULATOR receiver
FJ654_RS30565	COG2205	protein histidine kinase activity
FJ654_RS30570	COG2358	TRAP transporter, solute receptor (TAXI family
FJ654_RS30585	COG4585	Histidine kinase
FJ654_RS30590	COG2197	response regulator
FJ654_RS30605	COG0137	argininosuccinate synthase activity
FJ654_RS30610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJ654_RS30635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FJ654_RS30645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FJ654_RS30650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FJ654_RS30660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FJ654_RS30690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FJ654_RS30695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FJ654_RS30700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJ654_RS30720	COG0588	phosphoglycerate mutase activity
FJ654_RS30745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FJ654_RS30760	COG0514	ATP-dependent DNA helicase (RecQ)
FJ654_RS30785	COG1802	Transcriptional regulator
FJ654_RS30790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FJ654_RS30805	COG0187	DNA topoisomerase II activity
FJ654_RS30820	COG2197	response regulator
FJ654_RS30830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJ654_RS30835	COG4565	transcriptional regulatory protein
FJ654_RS30845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJ654_RS30855	COG4565	transcriptional regulatory protein
FJ654_RS30860	COG3290	protein histidine kinase activity
FJ654_RS30875	COG0372	Belongs to the citrate synthase family
FJ654_RS30895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FJ654_RS30900	COG0612	Peptidase, M16
FJ654_RS30915	COG1802	Transcriptional regulator
FJ654_RS30920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FJ654_RS30930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FJ654_RS30930	COG1042	CoA-binding domain protein
FJ654_RS30930	COG0045	succinate-CoA ligase (ADP-forming) activity
FJ654_RS30945	COG1435	thymidine kinase activity
FJ654_RS30980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FJ654_RS30990	COG0745	RESPONSE REGULATOR receiver
FJ654_RS30995	COG2205	protein histidine kinase activity
FJ654_RS31020	COG0756	dUTP diphosphatase activity
FJ654_RS31035	COG4591	ABC-type transport system involved in lipoprotein release permease component
FJ654_RS31035	COG1136	(ABC) transporter
FJ654_RS31065	COG0569	domain protein
FJ654_RS31070	COG0531	amino acid
FJ654_RS31075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FJ654_RS31080	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS31100	COG0436	Aminotransferase
FJ654_RS31140	COG0247	lactate metabolic process
FJ654_RS31140	COG0277	FAD linked oxidase domain protein
FJ654_RS31160	COG1799	cell septum assembly
FJ654_RS31195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FJ654_RS31210	COG2235	arginine
FJ654_RS31215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FJ654_RS31225	COG1024	Enoyl-CoA hydratase
FJ654_RS31290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FJ654_RS31305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FJ654_RS31310	COG2205	protein histidine kinase activity
FJ654_RS31325	COG3458	cephalosporin-C deacetylase activity
FJ654_RS31330	COG4209	transmembrane transport
FJ654_RS31335	COG0395	ABC-type sugar transport system, permease component
FJ654_RS31365	COG1653	transport
FJ654_RS31370	COG1175	transmembrane transport
FJ654_RS31375	COG0395	ABC-type sugar transport system, permease component
FJ654_RS31380	COG1940	carbohydrate kinase activity
FJ654_RS31385	COG4213	ABC transporter substrate-binding protein
FJ654_RS31395	COG4214	carbohydrate transport
FJ654_RS31400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FJ654_RS31405	COG0531	amino acid
FJ654_RS31420	COG1024	Enoyl-CoA hydratase
FJ654_RS31420	COG1250	3-hydroxyacyl-CoA dehydrogenase
FJ654_RS31425	COG0183	Belongs to the thiolase family
FJ654_RS31440	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FJ654_RS31455	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FJ654_RS31470	COG0446	pyridine nucleotide-disulphide oxidoreductase
FJ654_RS31485	COG3253	May function as heme-dependent peroxidase
FJ654_RS31505	COG3220	belongs to the UPF0276 family
FJ654_RS31525	COG0723	plastoquinol--plastocyanin reductase activity
FJ654_RS31525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FJ654_RS31530	COG2326	polyphosphate kinase activity
FJ654_RS31540	COG0330	HflC and HflK could
FJ654_RS31575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FJ654_RS31580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJ654_RS31585	COG1472	Belongs to the glycosyl hydrolase 3 family
FJ654_RS31605	COG0395	ABC-type sugar transport system, permease component
FJ654_RS31610	COG1175	transmembrane transport
FJ654_RS31630	COG1737	Transcriptional regulator
FJ654_RS31635	COG4821	SIS domain
FJ654_RS31640	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FJ654_RS31660	COG3903	Transcriptional regulator
FJ654_RS31660	COG3629	intracellular signal transduction
FJ654_RS31670	COG1595	DNA-templated transcription, initiation
FJ654_RS31675	COG0791	NLP P60 protein
FJ654_RS31675	COG3883	PFAM NLP P60 protein
FJ654_RS31680	COG2205	protein histidine kinase activity
FJ654_RS31685	COG0745	RESPONSE REGULATOR receiver
FJ654_RS31690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FJ654_RS31690	COG1017	nitric oxide dioxygenase activity
FJ654_RS31700	COG1477	protein flavinylation
FJ654_RS31710	COG1174	glycine betaine transport
FJ654_RS31715	COG1174	glycine betaine transport
FJ654_RS31730	COG2018	Roadblock/LC7 domain
FJ654_RS31735	COG5002	protein histidine kinase activity
FJ654_RS31770	COG3340	Belongs to the peptidase S51 family
FJ654_RS31795	COG1404	Belongs to the peptidase S8 family
FJ654_RS31810	COG1309	transcriptional regulator
FJ654_RS31825	COG3903	Transcriptional regulator
FJ654_RS31825	COG3629	intracellular signal transduction
FJ654_RS31845	COG3173	Aminoglycoside phosphotransferase
FJ654_RS31925	COG1175	transmembrane transport
FJ654_RS31945	COG2409	Drug exporters of the RND superfamily
FJ654_RS31960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FJ654_RS31975	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FJ654_RS32000	COG0529	Catalyzes the synthesis of activated sulfate
FJ654_RS32005	COG0175	sulfate reduction
FJ654_RS32035	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS32095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS32100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJ654_RS32115	COG2409	Drug exporters of the RND superfamily
FJ654_RS32125	COG0604	alcohol dehydrogenase
FJ654_RS32125	COG3321	synthase
FJ654_RS32125	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS32135	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS32155	COG2040	homocysteine
FJ654_RS32180	COG2755	lipolytic protein G-D-S-L family
FJ654_RS32190	COG0596	Alpha beta hydrolase
FJ654_RS32235	COG1131	(ABC) transporter
FJ654_RS32245	COG0395	ABC-type sugar transport system, permease component
FJ654_RS32270	COG0277	FAD linked oxidase domain protein
FJ654_RS32285	COG5297	Belongs to the glycosyl hydrolase family 6
FJ654_RS32295	COG3938	Belongs to the proline racemase family
FJ654_RS32300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJ654_RS32315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FJ654_RS32325	COG1162	GTPase activity
FJ654_RS32355	COG0028	Belongs to the TPP enzyme family
FJ654_RS32390	COG1802	Transcriptional regulator
FJ654_RS32400	COG3835	regulator
FJ654_RS32415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FJ654_RS32420	COG2252	PERMEase
FJ654_RS32440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FJ654_RS32510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS32550	COG0076	glutamate decarboxylase activity
FJ654_RS32590	COG0745	RESPONSE REGULATOR receiver
FJ654_RS32595	COG5002	protein histidine kinase activity
FJ654_RS32630	COG0598	Magnesium transport protein CorA
FJ654_RS32655	COG2197	response regulator
FJ654_RS32660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJ654_RS32665	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS32675	COG3960	tartronate-semialdehyde synthase activity
FJ654_RS32680	COG2084	Dehydrogenase
FJ654_RS32685	COG3622	Belongs to the hyi family
FJ654_RS32705	COG2351	hydroxyisourate hydrolase activity
FJ654_RS32720	COG2233	PERMEase
FJ654_RS32750	COG0406	alpha-ribazole phosphatase activity
FJ654_RS32765	COG0436	Aminotransferase
FJ654_RS32770	COG1733	regulation of RNA biosynthetic process
FJ654_RS32785	COG4264	IucA IucC family
FJ654_RS32820	COG0515	serine threonine protein kinase
FJ654_RS32820	COG2815	serine threonine protein kinase
FJ654_RS32840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FJ654_RS32845	COG0746	molybdenum cofactor guanylyltransferase activity
FJ654_RS32860	COG1414	Transcriptional regulator
FJ654_RS32865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FJ654_RS32870	COG4266	Belongs to the allantoicase family
FJ654_RS32875	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS32885	COG4585	Histidine kinase
FJ654_RS32890	COG2197	response regulator
FJ654_RS32900	COG0673	inositol 2-dehydrogenase activity
FJ654_RS32905	COG2188	Transcriptional regulator
FJ654_RS32910	COG1940	carbohydrate kinase activity
FJ654_RS32920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FJ654_RS32930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FJ654_RS32935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FJ654_RS32955	COG1126	abc transporter atp-binding protein
FJ654_RS32970	COG0405	Gamma-glutamyltransferase
FJ654_RS32975	COG0542	response to heat
FJ654_RS33005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FJ654_RS33020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FJ654_RS33030	COG1953	Uracil, thiamine, allantoin
FJ654_RS33050	COG2197	response regulator
FJ654_RS33055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FJ654_RS33070	COG0483	inositol monophosphate 1-phosphatase activity
FJ654_RS33080	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FJ654_RS33095	COG0640	Transcriptional regulator
FJ654_RS33125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FJ654_RS33130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FJ654_RS33150	COG1929	Belongs to the glycerate kinase type-1 family
FJ654_RS33190	COG0688	phosphatidylethanolamine metabolic process
FJ654_RS33195	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS33210	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS33210	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJ654_RS33215	COG0604	alcohol dehydrogenase
FJ654_RS33225	COG1250	3-hydroxyacyl-CoA dehydrogenase
FJ654_RS33240	COG0251	oxidation-reduction process
FJ654_RS33270	COG2226	methyltransferase
FJ654_RS33275	COG3594	Acyltransferase
FJ654_RS33280	COG2362	D-Aminopeptidase
FJ654_RS33285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FJ654_RS33290	COG4946	Tricorn protease homolog
FJ654_RS33290	COG1506	peptidase
FJ654_RS33290	COG0823	Involved in the tonB-independent uptake of proteins
FJ654_RS33295	COG1619	proteins homologs of microcin C7 resistance protein MccF
FJ654_RS33310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FJ654_RS33340	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS33345	COG4948	Mandelate Racemase Muconate Lactonizing
FJ654_RS33350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS33360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FJ654_RS33365	COG1793	dna ligase
FJ654_RS33365	COG3285	dna ligase
FJ654_RS33425	COG2226	methyltransferase
FJ654_RS33430	COG0488	(ABC) transporter
FJ654_RS33450	COG0693	protein deglycase activity
FJ654_RS33460	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FJ654_RS33460	COG0517	IMP dehydrogenase activity
FJ654_RS33470	COG2267	carboxylic ester hydrolase activity
FJ654_RS33475	COG0028	Belongs to the TPP enzyme family
FJ654_RS33540	COG0443	Heat shock 70 kDa protein
FJ654_RS33565	COG2154	pterin-4-alpha-carbinolamine dehydratase
FJ654_RS33570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FJ654_RS33580	COG5297	Belongs to the glycosyl hydrolase family 6
FJ654_RS33580	COG4733	cellulase activity
FJ654_RS33585	COG5297	Belongs to the glycosyl hydrolase family 6
FJ654_RS33605	COG0656	L-ascorbic acid biosynthetic process
FJ654_RS33625	COG3469	chitinase activity
FJ654_RS33630	COG3250	beta-galactosidase activity
FJ654_RS33640	COG0477	Major facilitator Superfamily
FJ654_RS33665	COG1335	isochorismatase
FJ654_RS33670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FJ654_RS33680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJ654_RS33690	COG0702	epimerase
FJ654_RS33695	COG1940	carbohydrate kinase activity
FJ654_RS33705	COG1129	ABC transporter
FJ654_RS33710	COG1172	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS33720	COG0673	inositol 2-dehydrogenase activity
FJ654_RS33735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FJ654_RS33770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FJ654_RS33785	COG2223	nitrite transmembrane transporter activity
FJ654_RS33790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FJ654_RS33795	COG0045	succinate-CoA ligase (ADP-forming) activity
FJ654_RS33805	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS33810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FJ654_RS33820	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS33835	COG3383	formate dehydrogenase (NAD+) activity
FJ654_RS33845	COG0583	DNA-binding transcription factor activity
FJ654_RS33850	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS33855	COG0028	Belongs to the TPP enzyme family
FJ654_RS33860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FJ654_RS33875	COG1595	DNA-templated transcription, initiation
FJ654_RS33885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJ654_RS33890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FJ654_RS33910	COG0747	negative chemotaxis
FJ654_RS33915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJ654_RS33945	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS33965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FJ654_RS33995	COG3467	pyridoxamine 5'-phosphate
FJ654_RS34000	COG0346	lactoylglutathione lyase activity
FJ654_RS34005	COG0477	Major facilitator Superfamily
FJ654_RS34015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FJ654_RS34025	COG0588	phosphoglycerate mutase activity
FJ654_RS34030	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FJ654_RS34035	COG0166	Belongs to the GPI family
FJ654_RS34050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FJ654_RS34065	COG3511	phospholipase C
FJ654_RS34080	COG2382	esterase
FJ654_RS34080	COG3507	Belongs to the glycosyl hydrolase 43 family
FJ654_RS34080	COG3693	PFAM glycoside hydrolase, family 10
FJ654_RS34090	COG2409	Drug exporters of the RND superfamily
FJ654_RS34100	COG2197	response regulator
FJ654_RS34105	COG3850	Histidine kinase
FJ654_RS34130	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS34155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FJ654_RS34160	COG3250	beta-galactosidase activity
FJ654_RS34170	COG0395	ABC-type sugar transport system, permease component
FJ654_RS34185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS34195	COG1486	melibiose metabolic process
FJ654_RS34210	COG3469	chitinase activity
FJ654_RS34220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FJ654_RS34265	COG1175	transmembrane transport
FJ654_RS34270	COG0395	ABC-type sugar transport system, permease component
FJ654_RS34275	COG0366	Alpha amylase catalytic
FJ654_RS34290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJ654_RS34295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJ654_RS34335	COG0154	amidase activity
FJ654_RS34345	COG1595	DNA-templated transcription, initiation
FJ654_RS34360	COG1175	transmembrane transport
FJ654_RS34365	COG0395	ABC-type sugar transport system, permease component
FJ654_RS34370	COG1940	carbohydrate kinase activity
FJ654_RS34390	COG0477	Major facilitator Superfamily
FJ654_RS34395	COG3511	phospholipase C
FJ654_RS34425	COG1672	PFAM Archaeal ATPase
FJ654_RS34425	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FJ654_RS34435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FJ654_RS34440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FJ654_RS34445	COG3485	protocatechuate 3,4-dioxygenase
FJ654_RS34450	COG3485	protocatechuate 3,4-dioxygenase
FJ654_RS34455	COG0183	Belongs to the thiolase family
FJ654_RS34485	COG1793	dna ligase
FJ654_RS34580	COG1834	amidinotransferase
FJ654_RS34585	COG0488	(ABC) transporter
FJ654_RS34615	COG1515	deoxyribonuclease V activity
FJ654_RS34620	COG3268	Saccharopine dehydrogenase
FJ654_RS34630	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS34635	COG0183	Belongs to the thiolase family
FJ654_RS34640	COG1024	Enoyl-CoA hydratase
FJ654_RS34640	COG1250	3-hydroxyacyl-CoA dehydrogenase
FJ654_RS34645	COG0789	Transcriptional regulator
FJ654_RS34650	COG1113	amino acid transport
FJ654_RS34665	COG2936	dipeptidyl-peptidase activity
FJ654_RS34670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FJ654_RS34680	COG0488	(ABC) transporter
FJ654_RS34690	COG2183	response to ionizing radiation
FJ654_RS34700	COG4977	sequence-specific DNA binding
FJ654_RS34710	COG1024	Enoyl-CoA hydratase
FJ654_RS34725	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FJ654_RS34775	COG1134	teichoic acid transport
FJ654_RS34780	COG1562	ergosterol biosynthetic process
FJ654_RS34790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FJ654_RS34800	COG1657	PFAM Prenyltransferase squalene oxidase
FJ654_RS34815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FJ654_RS34820	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FJ654_RS34840	COG2365	Tyrosine phosphatase family
FJ654_RS34850	COG4942	peptidase
FJ654_RS34855	COG2755	lipolytic protein G-D-S-L family
FJ654_RS34905	COG1063	alcohol dehydrogenase
FJ654_RS34910	COG0156	8-amino-7-oxononanoate synthase activity
FJ654_RS34915	COG0583	DNA-binding transcription factor activity
FJ654_RS34940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FJ654_RS34985	COG0174	glutamine synthetase
FJ654_RS34995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJ654_RS35055	COG0494	nUDIX hydrolase
FJ654_RS35070	COG1086	Polysaccharide biosynthesis protein
FJ654_RS35075	COG1316	TRANSCRIPTIONal
FJ654_RS35125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FJ654_RS35130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJ654_RS35155	COG3387	PFAM Glycoside hydrolase 15-related
FJ654_RS35160	COG2188	Transcriptional regulator
FJ654_RS35165	COG3962	Belongs to the TPP enzyme family
FJ654_RS35195	COG0673	inositol 2-dehydrogenase activity
FJ654_RS35215	COG0673	inositol 2-dehydrogenase activity
FJ654_RS35220	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS35240	COG1609	Transcriptional regulator
FJ654_RS35260	COG0477	Major facilitator Superfamily
FJ654_RS35315	COG1597	lipid kinase activity
FJ654_RS35345	COG1132	(ABC) transporter
FJ654_RS35350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FJ654_RS35355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FJ654_RS35400	COG0438	transferase activity, transferring glycosyl groups
FJ654_RS35410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FJ654_RS35425	COG4310	Domain of unknown function (DUF2172)
FJ654_RS35435	COG1215	transferase activity, transferring glycosyl groups
FJ654_RS35450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FJ654_RS35460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FJ654_RS35465	COG1063	alcohol dehydrogenase
FJ654_RS35470	COG0129	dihydroxy-acid dehydratase activity
FJ654_RS35475	COG0435	Glutathione S-transferase
FJ654_RS35485	COG1126	abc transporter atp-binding protein
FJ654_RS35500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS35505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS35510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS35515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS35580	COG1404	Belongs to the peptidase S8 family
FJ654_RS35605	COG2838	Isocitrate dehydrogenase
FJ654_RS35615	COG0668	transmembrane transport
FJ654_RS35625	COG1132	(ABC) transporter
FJ654_RS35670	COG0443	Heat shock 70 kDa protein
FJ654_RS35675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FJ654_RS35690	COG0542	response to heat
FJ654_RS35710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FJ654_RS35725	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FJ654_RS35745	COG0297	glycogen (starch) synthase activity
FJ654_RS35750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FJ654_RS35775	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS35805	COG2186	Transcriptional regulator
FJ654_RS35810	COG1879	ABC-type sugar transport system periplasmic component
FJ654_RS35815	COG1129	ABC transporter
FJ654_RS35825	COG4948	Mandelate Racemase Muconate Lactonizing
FJ654_RS35830	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS35845	COG3618	amidohydrolase
FJ654_RS35860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FJ654_RS35910	COG0726	polysaccharide deacetylase
FJ654_RS35955	COG0583	DNA-binding transcription factor activity
FJ654_RS35965	COG1053	succinate dehydrogenase
FJ654_RS35970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FJ654_RS35990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS36000	COG0523	cobalamin synthesis protein
FJ654_RS36020	COG3360	Dodecin
FJ654_RS36030	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FJ654_RS36035	COG0121	glutamine amidotransferase
FJ654_RS36040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FJ654_RS36045	COG3572	ergothioneine biosynthetic process
FJ654_RS36060	COG2268	Band 7 protein
FJ654_RS36100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FJ654_RS36110	COG0640	Transcriptional regulator
FJ654_RS36145	COG0281	malic enzyme
FJ654_RS36150	COG1609	Transcriptional regulator
FJ654_RS36180	COG1595	DNA-templated transcription, initiation
FJ654_RS36190	COG3284	Transcriptional regulator
FJ654_RS36200	COG3485	protocatechuate 3,4-dioxygenase
FJ654_RS36205	COG1454	alcohol dehydrogenase
FJ654_RS36210	COG2353	YceI-like domain
FJ654_RS36225	COG2197	response regulator
FJ654_RS36245	COG0300	oxidoreductase activity
FJ654_RS36305	COG1609	Transcriptional regulator
FJ654_RS36320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FJ654_RS36330	COG0242	peptide deformylase activity
FJ654_RS36370	COG1920	GTP binding
FJ654_RS36375	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJ654_RS36395	COG2197	response regulator
FJ654_RS36430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS36440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS36455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJ654_RS36460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJ654_RS36470	COG1960	acyl-CoA dehydrogenase activity
FJ654_RS36500	COG2828	Protein conserved in bacteria
FJ654_RS36505	COG1301	dicarboxylic acid transport
FJ654_RS36515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FJ654_RS36520	COG1120	ATPase activity
FJ654_RS36545	COG2197	response regulator
FJ654_RS36565	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FJ654_RS36580	COG2186	Transcriptional regulator
FJ654_RS36600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FJ654_RS36605	COG1609	Transcriptional regulator
FJ654_RS36645	COG0542	response to heat
FJ654_RS36660	COG3940	Belongs to the glycosyl hydrolase 43 family
FJ654_RS36665	COG3250	beta-galactosidase activity
FJ654_RS36670	COG1556	Lactate utilization protein
FJ654_RS36675	COG1139	Iron-sulfur cluster binding protein
FJ654_RS36680	COG0247	lactate metabolic process
FJ654_RS36685	COG1070	Carbohydrate kinase
FJ654_RS36690	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS36690	COG3347	Dehydrogenase
FJ654_RS36695	COG4952	isomerase
FJ654_RS36700	COG1129	ABC transporter
FJ654_RS36705	COG1172	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS36710	COG1172	Belongs to the binding-protein-dependent transport system permease family
FJ654_RS36730	COG1609	Transcriptional regulator
FJ654_RS36745	COG1357	PFAM Pentapeptide repeats (8 copies)
FJ654_RS36755	COG1309	transcriptional regulator
FJ654_RS36765	COG2706	6-phosphogluconolactonase activity
FJ654_RS36800	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS36830	COG1940	carbohydrate kinase activity
FJ654_RS36860	COG0546	phosphoglycolate phosphatase activity
FJ654_RS36865	COG1796	DNA polymerase
FJ654_RS36865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FJ654_RS36870	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS36900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FJ654_RS36900	COG2111	Na H antiporter
FJ654_RS36910	COG1006	Multisubunit Na H antiporter MnhC subunit
FJ654_RS36915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJ654_RS36935	COG1846	Transcriptional regulator
FJ654_RS36940	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS36990	COG0435	Glutathione S-transferase
FJ654_RS37010	COG2124	cytochrome p450
FJ654_RS37030	COG0667	Aldo Keto reductase
FJ654_RS37070	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FJ654_RS37125	COG2890	protein-(glutamine-N5) methyltransferase activity
FJ654_RS37140	COG0248	Ppx GppA phosphatase
FJ654_RS37185	COG2197	response regulator
FJ654_RS37195	COG1132	(ABC) transporter
FJ654_RS37205	COG0515	serine threonine protein kinase
FJ654_RS37215	COG0517	IMP dehydrogenase activity
FJ654_RS37235	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FJ654_RS37285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FJ654_RS37310	COG1132	(ABC) transporter
FJ654_RS37365	COG1846	Transcriptional regulator
FJ654_RS37365	COG1940	carbohydrate kinase activity
FJ654_RS37380	COG2072	flavoprotein involved in K transport
FJ654_RS37390	COG1309	transcriptional regulator
FJ654_RS37410	COG1309	transcriptional regulator
FJ654_RS37470	COG1940	carbohydrate kinase activity
FJ654_RS37485	COG0395	ABC-type sugar transport system, permease component
FJ654_RS37505	COG1072	(Pantothenic acid kinase))
FJ654_RS37535	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FJ654_RS37540	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FJ654_RS37570	COG2409	Drug exporters of the RND superfamily
FJ654_RS37590	COG0673	inositol 2-dehydrogenase activity
FJ654_RS37595	COG0667	Aldo Keto reductase
FJ654_RS37675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FJ654_RS37680	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FJ654_RS37685	COG2080	2 iron, 2 sulfur cluster binding
FJ654_RS37715	COG2755	lipolytic protein G-D-S-L family
FJ654_RS37740	COG1846	Transcriptional regulator
FJ654_RS37755	COG3290	protein histidine kinase activity
FJ654_RS37770	COG0640	Transcriptional regulator
FJ654_RS37800	COG1473	amidohydrolase
FJ654_RS37800	COG1473	amidohydrolase
FJ654_RS37825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJ654_RS37855	COG4977	sequence-specific DNA binding
FJ654_RS37885	COG5002	protein histidine kinase activity
FJ654_RS37890	COG0745	RESPONSE REGULATOR receiver
FJ654_RS37905	COG1136	(ABC) transporter
FJ654_RS37910	COG1136	(ABC) transporter
FJ654_RS37910	COG0577	efflux transmembrane transporter activity
FJ654_RS37915	COG2045	Belongs to the ComB family
FJ654_RS37930	COG3046	protein related to deoxyribodipyrimidine photolyase
FJ654_RS37955	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS37965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJ654_RS38000	COG0142	geranyltranstransferase activity
FJ654_RS38020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FJ654_RS38035	COG0596	Alpha beta hydrolase
FJ654_RS38040	COG2208	phosphoserine phosphatase activity
FJ654_RS38040	COG2770	Histidine kinase
FJ654_RS38050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FJ654_RS38055	COG0546	phosphoglycolate phosphatase activity
FJ654_RS38070	COG3848	Pyruvate phosphate dikinase
FJ654_RS38070	COG0574	Belongs to the PEP-utilizing enzyme family
FJ654_RS38080	COG0183	Belongs to the thiolase family
FJ654_RS38085	COG3396	Phenylacetate-CoA oxygenase
FJ654_RS38090	COG3460	Phenylacetate-CoA oxygenase
FJ654_RS38095	COG3396	Phenylacetate-CoA oxygenase
FJ654_RS38100	COG2151	metal-sulfur cluster biosynthetic enzyme
FJ654_RS38105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FJ654_RS38110	COG1295	ribonuclease BN
FJ654_RS38130	COG0671	phosphoesterase, PA-phosphatase related
FJ654_RS38135	COG0671	phosphoesterase, PA-phosphatase related
FJ654_RS38145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FJ654_RS38200	COG3345	alpha-galactosidase
FJ654_RS38300	COG4733	cellulase activity
FJ654_RS38300	COG5297	Belongs to the glycosyl hydrolase family 6
FJ654_RS38305	COG5297	Belongs to the glycosyl hydrolase family 6
FJ654_RS38315	COG0402	S-adenosylhomocysteine deaminase activity
FJ654_RS38335	COG0477	Major facilitator Superfamily
FJ654_RS38350	COG0753	catalase activity
FJ654_RS38365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FJ654_RS38370	COG1802	Transcriptional regulator
FJ654_RS38430	COG2226	methyltransferase
FJ654_RS38470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FJ654_RS38480	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FJ654_RS38500	COG0726	polysaccharide deacetylase
FJ654_RS38555	COG1131	(ABC) transporter
FJ654_RS38560	COG1725	Transcriptional regulator
FJ654_RS38580	COG2860	membrane
FJ654_RS38610	COG4585	Histidine kinase
FJ654_RS38615	COG2197	response regulator
FJ654_RS38635	COG1278	Cold shock
FJ654_RS38640	COG1295	ribonuclease BN
FJ654_RS38700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FJ654_RS38705	COG0254	rRNA binding
FJ654_RS38730	COG0577	efflux transmembrane transporter activity
FJ654_RS38730	COG1136	(ABC) transporter
FJ654_RS38750	COG4935	Belongs to the peptidase S8 family
FJ654_RS38750	COG2234	aminopeptidase activity
FJ654_RS38760	COG5002	protein histidine kinase activity
FJ654_RS38765	COG0745	RESPONSE REGULATOR receiver
FJ654_RS38810	COG2124	cytochrome p450
FJ654_RS38815	COG3629	intracellular signal transduction
FJ654_RS38815	COG3903	Transcriptional regulator
FJ654_RS38840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJ654_RS38895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS38905	COG2326	polyphosphate kinase activity
FJ654_RS38940	COG1609	Transcriptional regulator
FJ654_RS38955	COG1129	ABC transporter
FJ654_RS38960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJ654_RS38970	COG3718	enzyme involved in inositol metabolism
FJ654_RS38975	COG3962	Belongs to the TPP enzyme family
FJ654_RS38990	COG1082	Xylose isomerase domain protein TIM barrel
FJ654_RS38995	COG1082	Xylose isomerase domain protein TIM barrel
FJ654_RS39015	COG1137	ATPase activity
FJ654_RS39040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJ654_RS39045	COG1414	Transcriptional regulator
FJ654_RS39060	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS39070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJ654_RS39075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS39080	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS39100	COG0477	Major facilitator Superfamily
FJ654_RS39110	COG2186	Transcriptional regulator
FJ654_RS39120	COG1609	Transcriptional regulator
FJ654_RS39150	COG2186	Transcriptional regulator
FJ654_RS39170	COG3507	Belongs to the glycosyl hydrolase 43 family
FJ654_RS39175	COG1506	peptidase
FJ654_RS39175	COG0823	Involved in the tonB-independent uptake of proteins
FJ654_RS39190	COG0492	ferredoxin-NADP+ reductase activity
FJ654_RS39230	COG2267	carboxylic ester hydrolase activity
FJ654_RS39245	COG1024	Enoyl-CoA hydratase
FJ654_RS39250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FJ654_RS39280	COG0604	alcohol dehydrogenase
FJ654_RS39290	COG0431	NADPH-dependent FMN reductase
FJ654_RS39300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJ654_RS39305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS39310	COG4608	Belongs to the ABC transporter superfamily
FJ654_RS39315	COG0444	Belongs to the ABC transporter superfamily
FJ654_RS39320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJ654_RS39325	COG0601	transmembrane transport
FJ654_RS39360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJ654_RS39370	COG3971	2-oxopent-4-enoate hydratase activity
FJ654_RS39375	COG1414	Transcriptional regulator
FJ654_RS39380	COG2272	Belongs to the type-B carboxylesterase lipase family
FJ654_RS39385	COG3693	PFAM glycoside hydrolase, family 10
FJ654_RS39410	COG0583	DNA-binding transcription factor activity
FJ654_RS39415	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FJ654_RS39435	COG0318	PFAM AMP-dependent synthetase and ligase
FJ654_RS39445	COG3971	2-oxopent-4-enoate hydratase activity
FJ654_RS39460	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
FJ654_RS39475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS39480	COG4172	Belongs to the ABC transporter superfamily
FJ654_RS39485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJ654_RS39495	COG0747	negative chemotaxis
FJ654_RS39510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS39515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS39520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS39535	COG2040	homocysteine
FJ654_RS39540	COG1126	abc transporter atp-binding protein
FJ654_RS39545	COG0765	amino acid transport
FJ654_RS39555	COG1414	Transcriptional regulator
FJ654_RS39565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJ654_RS39575	COG0583	DNA-binding transcription factor activity
FJ654_RS39590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJ654_RS39595	COG1116	anion transmembrane transporter activity
FJ654_RS39610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FJ654_RS39620	COG0277	FAD linked oxidase domain protein
FJ654_RS39635	COG2409	Drug exporters of the RND superfamily
FJ654_RS39720	COG1819	glycosyl
FJ654_RS39760	COG0395	ABC-type sugar transport system, permease component
FJ654_RS39765	COG1175	transmembrane transport
FJ654_RS39770	COG2182	Extracellular solute-binding protein
FJ654_RS39850	COG1366	Belongs to the anti-sigma-factor antagonist family
FJ654_RS39880	COG2084	Dehydrogenase
FJ654_RS39930	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FJ654_RS39935	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FJ654_RS39940	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FJ654_RS39950	COG0583	DNA-binding transcription factor activity
FJ654_RS39955	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS39980	COG1882	Formate acetyltransferase
FJ654_RS39985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FJ654_RS39995	COG4191	Histidine kinase
FJ654_RS40030	COG0205	6-phosphofructokinase activity
FJ654_RS40040	COG1063	alcohol dehydrogenase
FJ654_RS40055	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FJ654_RS40070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FJ654_RS40110	COG0549	Belongs to the carbamate kinase family
FJ654_RS40135	COG0516	GMP reductase activity
FJ654_RS40135	COG0517	IMP dehydrogenase activity
FJ654_RS40150	COG0309	Hydrogenase expression formation protein (HypE)
FJ654_RS40160	COG0516	GMP reductase activity
FJ654_RS40160	COG0517	IMP dehydrogenase activity
FJ654_RS40195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FJ654_RS40210	COG0574	Belongs to the PEP-utilizing enzyme family
FJ654_RS40210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FJ654_RS40215	COG0402	S-adenosylhomocysteine deaminase activity
FJ654_RS40245	COG4221	oxidoreductase activity
FJ654_RS40260	COG2197	response regulator
FJ654_RS40270	COG3469	chitinase activity
FJ654_RS40295	COG1335	isochorismatase
FJ654_RS40345	COG0477	Major facilitator Superfamily
FJ654_RS40425	COG3250	beta-galactosidase activity
FJ654_RS40435	COG0488	(ABC) transporter
FJ654_RS40440	COG0488	(ABC) transporter
FJ654_RS40455	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FJ654_RS40485	COG1073	alpha beta
FJ654_RS40500	COG1309	transcriptional regulator
FJ654_RS40515	COG1733	regulation of RNA biosynthetic process
FJ654_RS40520	COG0702	epimerase
FJ654_RS40525	COG2319	Wd-40 repeat
FJ654_RS40525	COG4249	Peptidase C14 caspase catalytic subunit p20
FJ654_RS40575	COG4221	oxidoreductase activity
FJ654_RS40620	COG0174	glutamine synthetase
FJ654_RS40635	COG4689	acetoacetate decarboxylase
FJ654_RS40640	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS40650	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJ654_RS40660	COG2124	cytochrome p450
FJ654_RS40675	COG1012	belongs to the aldehyde dehydrogenase family
FJ654_RS40680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FJ654_RS40690	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FJ654_RS40700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FJ654_RS40710	COG4249	Peptidase C14 caspase catalytic subunit p20
FJ654_RS40710	COG2319	Wd-40 repeat
FJ654_RS40735	COG3940	Belongs to the glycosyl hydrolase 43 family
FJ654_RS40755	COG0583	DNA-binding transcription factor activity
FJ654_RS40770	COG4733	cellulase activity
FJ654_RS40770	COG5297	Belongs to the glycosyl hydrolase family 6
FJ654_RS40855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJ654_RS40870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJ654_RS40875	COG0069	glutamate synthase activity
FJ654_RS40880	COG0017	Asparaginyl-tRNA synthetase
FJ654_RS40900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FJ654_RS40905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FJ654_RS40910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FJ654_RS40925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FJ654_RS40930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJ654_RS40950	COG3903	Transcriptional regulator
FJ654_RS40950	COG3629	intracellular signal transduction
FJ654_RS41010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJ654_RS41025	COG0628	permease
FJ654_RS41035	COG1028	Short-chain dehydrogenase reductase Sdr
FJ654_RS41050	COG0300	oxidoreductase activity
FJ654_RS41065	COG0667	Aldo Keto reductase
FJ654_RS41070	COG0494	nUDIX hydrolase
FJ654_RS41080	COG1595	DNA-templated transcription, initiation
FJ654_RS41135	COG2080	2 iron, 2 sulfur cluster binding
FJ654_RS41140	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FJ654_RS41145	COG3608	succinylglutamate desuccinylase aspartoacylase
FJ654_RS41145	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FJ654_RS41150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FJ654_RS41180	COG2207	Transcriptional regulator
FJ654_RS41195	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FJ654_RS41235	COG0300	oxidoreductase activity
FJ654_RS41265	COG1252	NADH dehydrogenase
FJ654_RS41270	COG1595	DNA-templated transcription, initiation