locus-tag	class	description
DDJ31_RS00005	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDJ31_RS00010	COG0022	dehydrogenase e1 component
DDJ31_RS00020	COG1024	Enoyl-CoA hydratase
DDJ31_RS00030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS00060	COG2226	methyltransferase
DDJ31_RS00075	COG3335	DDE superfamily endonuclease
DDJ31_RS00105	COG0189	ligase activity
DDJ31_RS00125	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DDJ31_RS00125	COG0028	Belongs to the TPP enzyme family
DDJ31_RS00215	COG0477	Major facilitator Superfamily
DDJ31_RS00220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDJ31_RS00225	COG1024	Enoyl-CoA hydratase
DDJ31_RS00230	COG0583	DNA-binding transcription factor activity
DDJ31_RS00265	COG0515	serine threonine protein kinase
DDJ31_RS00280	COG1132	(ABC) transporter
DDJ31_RS00285	COG1132	(ABC) transporter
DDJ31_RS00290	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDJ31_RS00325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDJ31_RS00345	COG0667	Aldo Keto reductase
DDJ31_RS00360	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DDJ31_RS00395	COG2318	DinB family
DDJ31_RS00415	COG1414	Transcriptional regulator
DDJ31_RS00420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDJ31_RS00430	COG3833	ABC-type maltose transport systems, permease component
DDJ31_RS00460	COG4585	Histidine kinase
DDJ31_RS00465	COG2197	response regulator
DDJ31_RS00475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDJ31_RS00475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDJ31_RS00500	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDJ31_RS00510	COG2124	cytochrome p450
DDJ31_RS00540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDJ31_RS00545	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDJ31_RS00555	COG1129	ABC transporter
DDJ31_RS00560	COG1869	D-ribose catabolic process
DDJ31_RS00565	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DDJ31_RS00570	COG2188	Transcriptional regulator
DDJ31_RS00600	COG2814	Major facilitator Superfamily
DDJ31_RS00625	COG1349	DNA-binding transcription factor activity
DDJ31_RS00635	COG0583	DNA-binding transcription factor activity
DDJ31_RS00675	COG0477	Major facilitator Superfamily
DDJ31_RS00695	COG3959	Transketolase, thiamine diphosphate binding domain
DDJ31_RS00700	COG2259	Doxx family
DDJ31_RS00710	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS00720	COG4948	Mandelate Racemase Muconate Lactonizing
DDJ31_RS00725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DDJ31_RS00730	COG1414	Transcriptional regulator
DDJ31_RS00750	COG1175	transmembrane transport
DDJ31_RS00755	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS00775	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDJ31_RS00795	COG2190	(PTS) system
DDJ31_RS00795	COG2211	Major facilitator Superfamily
DDJ31_RS00800	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS00815	COG1819	glycosyl
DDJ31_RS00850	COG1793	dna ligase
DDJ31_RS00850	COG3285	dna ligase
DDJ31_RS00860	COG2267	carboxylic ester hydrolase activity
DDJ31_RS00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDJ31_RS00870	COG0254	rRNA binding
DDJ31_RS00875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDJ31_RS00885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDJ31_RS00935	COG3842	ATPase activity
DDJ31_RS00940	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDJ31_RS00945	COG1177	transmembrane transport
DDJ31_RS01020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDJ31_RS01040	COG2124	cytochrome p450
DDJ31_RS01050	COG1175	transmembrane transport
DDJ31_RS01055	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS01060	COG1609	Transcriptional regulator
DDJ31_RS01090	COG0385	Bile acid
DDJ31_RS01100	COG2124	cytochrome p450
DDJ31_RS01120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDJ31_RS01130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDJ31_RS01165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDJ31_RS01170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS01180	COG3251	PFAM MbtH domain protein
DDJ31_RS01190	COG3340	Belongs to the peptidase S51 family
DDJ31_RS01195	COG2197	response regulator
DDJ31_RS01200	COG2197	response regulator
DDJ31_RS01215	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DDJ31_RS01215	COG1672	PFAM Archaeal ATPase
DDJ31_RS01225	COG2124	cytochrome p450
DDJ31_RS01250	COG0604	alcohol dehydrogenase
DDJ31_RS01280	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS01285	COG0667	Aldo Keto reductase
DDJ31_RS01290	COG3345	alpha-galactosidase
DDJ31_RS01295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDJ31_RS01305	COG1397	ADP-ribosylglycohydrolase
DDJ31_RS01310	COG2188	Transcriptional regulator
DDJ31_RS01325	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DDJ31_RS01340	COG3469	chitinase activity
DDJ31_RS01355	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS01405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS01410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS01415	COG1120	ATPase activity
DDJ31_RS01440	COG0596	Alpha beta hydrolase
DDJ31_RS01450	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS01460	COG1349	DNA-binding transcription factor activity
DDJ31_RS01465	COG2223	nitrite transmembrane transporter activity
DDJ31_RS01490	COG2814	Major facilitator Superfamily
DDJ31_RS01500	COG4977	sequence-specific DNA binding
DDJ31_RS01510	COG1285	pathogenesis
DDJ31_RS01515	COG1609	Transcriptional regulator
DDJ31_RS01520	COG3250	beta-galactosidase activity
DDJ31_RS01530	COG1175	transmembrane transport
DDJ31_RS01535	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS01580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS01590	COG0444	Belongs to the ABC transporter superfamily
DDJ31_RS01595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDJ31_RS01600	COG0601	transmembrane transport
DDJ31_RS01615	COG1959	2 iron, 2 sulfur cluster binding
DDJ31_RS01635	COG0483	inositol monophosphate 1-phosphatase activity
DDJ31_RS01670	COG0477	Major facilitator Superfamily
DDJ31_RS01680	COG2375	cellular response to nickel ion
DDJ31_RS01700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS01705	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS01715	COG1120	ATPase activity
DDJ31_RS01720	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DDJ31_RS01725	COG2175	clavaminate synthase activity
DDJ31_RS01740	COG2084	Dehydrogenase
DDJ31_RS01745	COG1082	Xylose isomerase domain protein TIM barrel
DDJ31_RS01750	COG0149	triose-phosphate isomerase activity
DDJ31_RS01760	COG2376	Dihydroxyacetone kinase
DDJ31_RS01770	COG2186	Transcriptional regulator
DDJ31_RS01775	COG5001	Diguanylate cyclase
DDJ31_RS01775	COG3300	MHYT domain
DDJ31_RS01780	COG1295	ribonuclease BN
DDJ31_RS01835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDJ31_RS01840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDJ31_RS01855	COG1595	DNA-templated transcription, initiation
DDJ31_RS01870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDJ31_RS01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS01925	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS01935	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS01950	COG1309	transcriptional regulator
DDJ31_RS02025	COG0181	hydroxymethylbilane synthase activity
DDJ31_RS02035	COG0842	Transport permease protein
DDJ31_RS02075	COG0366	Alpha amylase catalytic
DDJ31_RS02090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DDJ31_RS02110	COG1366	Belongs to the anti-sigma-factor antagonist family
DDJ31_RS02130	COG2208	phosphoserine phosphatase activity
DDJ31_RS02130	COG2770	Histidine kinase
DDJ31_RS02150	COG1366	Belongs to the anti-sigma-factor antagonist family
DDJ31_RS02155	COG1366	Belongs to the anti-sigma-factor antagonist family
DDJ31_RS02175	COG1252	NADH dehydrogenase
DDJ31_RS02200	COG0477	Major facilitator Superfamily
DDJ31_RS02230	COG5002	protein histidine kinase activity
DDJ31_RS02235	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS02330	COG2340	Cysteine-rich secretory protein family
DDJ31_RS02345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDJ31_RS02345	COG0515	serine threonine protein kinase
DDJ31_RS02360	COG3647	Membrane
DDJ31_RS02365	COG0667	Aldo Keto reductase
DDJ31_RS02385	COG0328	RNA-DNA hybrid ribonuclease activity
DDJ31_RS02400	COG1309	transcriptional regulator
DDJ31_RS02415	COG0740	serine-type endopeptidase activity
DDJ31_RS02420	COG0740	serine-type endopeptidase activity
DDJ31_RS02425	COG1396	sequence-specific DNA binding
DDJ31_RS02430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDJ31_RS02435	COG1191	sigma factor activity
DDJ31_RS02455	COG0667	Aldo Keto reductase
DDJ31_RS02460	COG0583	DNA-binding transcription factor activity
DDJ31_RS02475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDJ31_RS02480	COG0346	lactoylglutathione lyase activity
DDJ31_RS02485	COG0667	Aldo Keto reductase
DDJ31_RS02495	COG2755	lipolytic protein G-D-S-L family
DDJ31_RS02500	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS02505	COG4941	Belongs to the sigma-70 factor family
DDJ31_RS02520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS02530	COG0431	NADPH-dependent FMN reductase
DDJ31_RS02535	COG0583	DNA-binding transcription factor activity
DDJ31_RS02550	COG1191	sigma factor activity
DDJ31_RS02555	COG2409	Drug exporters of the RND superfamily
DDJ31_RS02560	COG1846	Transcriptional regulator
DDJ31_RS02640	COG0673	inositol 2-dehydrogenase activity
DDJ31_RS02675	COG0589	response to stress
DDJ31_RS02700	COG1024	Enoyl-CoA hydratase
DDJ31_RS02705	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS02720	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS02730	COG2070	2-Nitropropane dioxygenase
DDJ31_RS02750	COG0515	serine threonine protein kinase
DDJ31_RS02790	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS02805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDJ31_RS02835	COG1733	regulation of RNA biosynthetic process
DDJ31_RS02840	COG4221	oxidoreductase activity
DDJ31_RS02840	COG3321	synthase
DDJ31_RS02840	COG0604	alcohol dehydrogenase
DDJ31_RS02840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS02855	COG1396	sequence-specific DNA binding
DDJ31_RS02870	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS02875	COG2376	Dihydroxyacetone kinase
DDJ31_RS02880	COG1461	Dihydroxyacetone kinase
DDJ31_RS02895	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS02905	COG5297	Belongs to the glycosyl hydrolase family 6
DDJ31_RS02905	COG4733	cellulase activity
DDJ31_RS02920	COG1902	pentaerythritol trinitrate reductase activity
DDJ31_RS02920	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDJ31_RS02940	COG2890	protein-(glutamine-N5) methyltransferase activity
DDJ31_RS02965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DDJ31_RS02980	COG3458	cephalosporin-C deacetylase activity
DDJ31_RS02985	COG2188	Transcriptional regulator
DDJ31_RS03000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS03025	COG2124	cytochrome p450
DDJ31_RS03030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DDJ31_RS03035	COG1686	Belongs to the peptidase S11 family
DDJ31_RS03045	COG2066	Belongs to the glutaminase family
DDJ31_RS03050	COG1027	Aspartate ammonia-lyase
DDJ31_RS03060	COG1113	amino acid transport
DDJ31_RS03065	COG2186	Transcriptional regulator
DDJ31_RS03070	COG1968	undecaprenyl-diphosphatase activity
DDJ31_RS03075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDJ31_RS03080	COG1993	acr, cog1993
DDJ31_RS03085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDJ31_RS03110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDJ31_RS03125	COG2423	ornithine cyclodeaminase activity
DDJ31_RS03150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DDJ31_RS03155	COG2814	Major facilitator Superfamily
DDJ31_RS03195	COG1175	transmembrane transport
DDJ31_RS03200	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS03215	COG1846	Transcriptional regulator
DDJ31_RS03275	COG3835	regulator
DDJ31_RS03325	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DDJ31_RS03365	COG1349	DNA-binding transcription factor activity
DDJ31_RS03395	COG1940	carbohydrate kinase activity
DDJ31_RS03405	COG2813	Specifically methylates the guanine in position
DDJ31_RS03415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDJ31_RS03420	COG1349	DNA-binding transcription factor activity
DDJ31_RS03425	COG3387	PFAM Glycoside hydrolase 15-related
DDJ31_RS03430	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DDJ31_RS03435	COG3433	isochorismatase activity
DDJ31_RS03435	COG1535	isochorismatase
DDJ31_RS03440	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DDJ31_RS03460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS03480	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DDJ31_RS03495	COG1169	isochorismate synthase
DDJ31_RS03500	COG1021	2,3-dihydroxybenzoate-AMP ligase
DDJ31_RS03505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS03510	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS03515	COG0596	Alpha beta hydrolase
DDJ31_RS03535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDJ31_RS03550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDJ31_RS03555	COG3938	Belongs to the proline racemase family
DDJ31_RS03565	COG3469	chitinase activity
DDJ31_RS03585	COG0738	Major facilitator superfamily
DDJ31_RS03590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDJ31_RS03610	COG0477	Major facilitator Superfamily
DDJ31_RS03615	COG1819	glycosyl
DDJ31_RS03620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DDJ31_RS03635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDJ31_RS03640	COG1660	Displays ATPase and GTPase activities
DDJ31_RS03670	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDJ31_RS03675	COG2086	electron transfer activity
DDJ31_RS03695	COG0204	Acyl-transferase
DDJ31_RS03720	COG0584	glycerophosphoryl diester phosphodiesterase
DDJ31_RS03755	COG0671	phosphoesterase, PA-phosphatase related
DDJ31_RS03765	COG1309	transcriptional regulator
DDJ31_RS03790	COG0640	Transcriptional regulator
DDJ31_RS03795	COG1902	pentaerythritol trinitrate reductase activity
DDJ31_RS03800	COG3509	depolymerase
DDJ31_RS03820	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS03835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDJ31_RS03885	COG1388	LysM domain
DDJ31_RS03885	COG0791	NLP P60 protein
DDJ31_RS03900	COG4948	Mandelate Racemase Muconate Lactonizing
DDJ31_RS03905	COG0583	DNA-binding transcription factor activity
DDJ31_RS03945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS03970	COG2890	protein-(glutamine-N5) methyltransferase activity
DDJ31_RS03990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDJ31_RS04020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDJ31_RS04025	COG1121	(ABC) transporter
DDJ31_RS04030	COG1120	ATPase activity
DDJ31_RS04035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS04070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDJ31_RS04085	COG2409	Drug exporters of the RND superfamily
DDJ31_RS04100	COG0432	Pfam Uncharacterised protein family UPF0047
DDJ31_RS04105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDJ31_RS04110	COG1116	anion transmembrane transporter activity
DDJ31_RS04120	COG2072	flavoprotein involved in K transport
DDJ31_RS04130	COG1132	(ABC) transporter
DDJ31_RS04135	COG1846	Transcriptional regulator
DDJ31_RS04140	COG1301	dicarboxylic acid transport
DDJ31_RS04160	COG1132	(ABC) transporter
DDJ31_RS04170	COG0254	rRNA binding
DDJ31_RS04185	COG1946	Acyl-CoA thioesterase
DDJ31_RS04195	COG2018	Roadblock/LC7 domain
DDJ31_RS04235	COG1070	Carbohydrate kinase
DDJ31_RS04240	COG1940	carbohydrate kinase activity
DDJ31_RS04240	COG1846	Transcriptional regulator
DDJ31_RS04260	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS04285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DDJ31_RS04300	COG3708	Transcriptional regulator
DDJ31_RS04300	COG2207	Transcriptional regulator
DDJ31_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS04405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS04410	COG1063	alcohol dehydrogenase
DDJ31_RS04415	COG5285	phytanoyl-CoA dioxygenase
DDJ31_RS04445	COG3555	Aspartyl Asparaginyl beta-hydroxylase
DDJ31_RS04475	COG0475	glutathione-regulated potassium exporter activity
DDJ31_RS04490	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DDJ31_RS04500	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS04555	COG1231	oxidoreductase activity
DDJ31_RS04560	COG2084	Dehydrogenase
DDJ31_RS04565	COG1309	transcriptional regulator
DDJ31_RS04600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDJ31_RS04635	COG0596	Alpha beta hydrolase
DDJ31_RS04640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDJ31_RS04645	COG0789	Transcriptional regulator
DDJ31_RS04660	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS04670	COG0583	DNA-binding transcription factor activity
DDJ31_RS04675	COG0483	inositol monophosphate 1-phosphatase activity
DDJ31_RS04685	COG2267	carboxylic ester hydrolase activity
DDJ31_RS04690	COG1309	transcriptional regulator
DDJ31_RS04735	COG0604	alcohol dehydrogenase
DDJ31_RS04740	COG1902	pentaerythritol trinitrate reductase activity
DDJ31_RS04760	COG2186	Transcriptional regulator
DDJ31_RS04780	COG4948	Mandelate Racemase Muconate Lactonizing
DDJ31_RS04785	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDJ31_RS04795	COG1653	transport
DDJ31_RS04800	COG1175	transmembrane transport
DDJ31_RS04835	COG1819	glycosyl
DDJ31_RS04850	COG1233	COG1233 Phytoene dehydrogenase and related
DDJ31_RS04935	COG1674	ftsk spoiiie
DDJ31_RS04940	COG1404	Belongs to the peptidase S8 family
DDJ31_RS04975	COG1366	Belongs to the anti-sigma-factor antagonist family
DDJ31_RS04980	COG1366	Belongs to the anti-sigma-factor antagonist family
DDJ31_RS04985	COG2172	sigma factor antagonist activity
DDJ31_RS04995	COG0784	Response regulator, receiver
DDJ31_RS04995	COG2198	Histidine kinase
DDJ31_RS04995	COG5002	protein histidine kinase activity
DDJ31_RS05000	COG0784	Response regulator, receiver
DDJ31_RS05055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDJ31_RS05065	COG0475	glutathione-regulated potassium exporter activity
DDJ31_RS05070	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS05095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS05165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DDJ31_RS05175	COG3959	Transketolase, thiamine diphosphate binding domain
DDJ31_RS05240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS05245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS05250	COG0659	secondary active sulfate transmembrane transporter activity
DDJ31_RS05255	COG0789	Transcriptional regulator
DDJ31_RS05270	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS05275	COG1175	transmembrane transport
DDJ31_RS05295	COG2814	Major facilitator Superfamily
DDJ31_RS05320	COG1335	isochorismatase
DDJ31_RS05340	COG4106	trans-aconitate 2-methyltransferase activity
DDJ31_RS05350	COG1120	ATPase activity
DDJ31_RS05355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS05375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DDJ31_RS05400	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS05405	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS05420	COG3634	alkyl hydroperoxide reductase activity
DDJ31_RS05425	COG1793	dna ligase
DDJ31_RS05450	COG3424	synthase
DDJ31_RS05455	COG2124	cytochrome p450
DDJ31_RS05465	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS05475	COG0242	peptide deformylase activity
DDJ31_RS05485	COG3442	glutamine amidotransferase
DDJ31_RS05490	COG0205	6-phosphofructokinase activity
DDJ31_RS05505	COG3275	phosphorelay sensor kinase activity
DDJ31_RS05510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDJ31_RS05520	COG3279	Response regulator of the LytR AlgR family
DDJ31_RS05525	COG1522	sequence-specific DNA binding
DDJ31_RS05530	COG1834	amidinotransferase
DDJ31_RS05535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDJ31_RS05565	COG0829	nickel cation binding
DDJ31_RS05570	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DDJ31_RS05580	COG0804	urea catabolic process
DDJ31_RS05585	COG0832	Belongs to the urease beta subunit family
DDJ31_RS05590	COG0831	urea catabolic process
DDJ31_RS05635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DDJ31_RS05640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDJ31_RS05645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DDJ31_RS05680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDJ31_RS05685	COG3663	DNA glycosylase
DDJ31_RS05690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDJ31_RS05755	COG1940	carbohydrate kinase activity
DDJ31_RS05760	COG2188	Transcriptional regulator
DDJ31_RS05765	COG0596	Alpha beta hydrolase
DDJ31_RS05775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDJ31_RS05830	COG1522	sequence-specific DNA binding
DDJ31_RS05835	COG0419	ATPase involved in DNA repair
DDJ31_RS05840	COG0420	3'-5' exonuclease activity
DDJ31_RS05845	COG1739	Uncharacterized protein family UPF0029
DDJ31_RS05860	COG0215	cysteine-tRNA ligase activity
DDJ31_RS05865	COG1832	CoA-binding protein
DDJ31_RS05870	COG0531	amino acid
DDJ31_RS05890	COG0110	maltose O-acetyltransferase activity
DDJ31_RS05915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDJ31_RS05935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDJ31_RS05965	COG1802	Transcriptional regulator
DDJ31_RS05980	COG1968	undecaprenyl-diphosphatase activity
DDJ31_RS05995	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS06000	COG1011	Hydrolase
DDJ31_RS06010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DDJ31_RS06020	COG2318	DinB family
DDJ31_RS06035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDJ31_RS06120	COG1695	Transcriptional regulator
DDJ31_RS06135	COG0667	Aldo Keto reductase
DDJ31_RS06150	COG0137	argininosuccinate synthase activity
DDJ31_RS06160	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DDJ31_RS06190	COG1609	Transcriptional regulator
DDJ31_RS06200	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS06205	COG1175	transmembrane transport
DDJ31_RS06215	COG0531	amino acid
DDJ31_RS06245	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DDJ31_RS06245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DDJ31_RS06255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDJ31_RS06295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DDJ31_RS06325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDJ31_RS06335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDJ31_RS06350	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DDJ31_RS06375	COG2018	Roadblock/LC7 domain
DDJ31_RS06390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDJ31_RS06395	COG2146	nitrite reductase [NAD(P)H] activity
DDJ31_RS06400	COG1414	Transcriptional regulator
DDJ31_RS06415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDJ31_RS06420	COG4638	Rieske (2fe-2S)
DDJ31_RS06425	COG0531	amino acid
DDJ31_RS06450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DDJ31_RS06455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DDJ31_RS06460	COG1984	allophanate hydrolase subunit 2
DDJ31_RS06470	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS06500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDJ31_RS06505	COG2364	Membrane
DDJ31_RS06515	COG2270	Major facilitator Superfamily
DDJ31_RS06530	COG1216	Glycosyl transferase, family 2
DDJ31_RS06555	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS06605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DDJ31_RS06610	COG0140	phosphoribosyl-ATP diphosphatase activity
DDJ31_RS06615	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DDJ31_RS06620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDJ31_RS06620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDJ31_RS06625	COG3201	nicotinamide mononucleotide transporter
DDJ31_RS06635	COG1595	DNA-templated transcription, initiation
DDJ31_RS06640	COG0702	epimerase
DDJ31_RS06645	COG1846	Transcriptional regulator
DDJ31_RS06645	COG1940	carbohydrate kinase activity
DDJ31_RS06650	COG2223	nitrite transmembrane transporter activity
DDJ31_RS06655	COG2233	PERMEase
DDJ31_RS06670	COG2318	DinB family
DDJ31_RS06685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDJ31_RS06695	COG0531	amino acid
DDJ31_RS06715	COG2390	Transcriptional regulator
DDJ31_RS06720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDJ31_RS06730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DDJ31_RS06765	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DDJ31_RS06775	COG1758	RNA polymerase activity
DDJ31_RS06780	COG0194	GDP metabolic process
DDJ31_RS06790	COG0284	orotidine-5'-phosphate decarboxylase activity
DDJ31_RS06795	COG0167	dihydroorotate dehydrogenase activity
DDJ31_RS06800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDJ31_RS06805	COG0505	Belongs to the CarA family
DDJ31_RS06815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDJ31_RS06820	COG0540	Belongs to the ATCase OTCase family
DDJ31_RS06825	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DDJ31_RS06835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDJ31_RS06840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DDJ31_RS06845	COG0006	proline dipeptidase activity
DDJ31_RS06855	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DDJ31_RS06860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DDJ31_RS06865	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DDJ31_RS06870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDJ31_RS06875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDJ31_RS06880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DDJ31_RS06885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DDJ31_RS06905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DDJ31_RS06920	COG0124	histidyl-tRNA synthetase
DDJ31_RS06930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DDJ31_RS06935	COG1196	nuclear chromosome segregation
DDJ31_RS06940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDJ31_RS06945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDJ31_RS06950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDJ31_RS06955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDJ31_RS06965	COG2255	four-way junction helicase activity
DDJ31_RS06970	COG0632	four-way junction helicase activity
DDJ31_RS06975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DDJ31_RS06980	COG0217	transcriptional regulatory protein
DDJ31_RS06985	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DDJ31_RS06990	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DDJ31_RS07000	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS07005	COG1560	Kdo2-lipid A biosynthetic process
DDJ31_RS07010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDJ31_RS07035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDJ31_RS07050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDJ31_RS07080	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS07085	COG1175	transmembrane transport
DDJ31_RS07090	COG1653	transport
DDJ31_RS07130	COG0456	acetyltransferase
DDJ31_RS07140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DDJ31_RS07140	COG0512	Glutamine amidotransferase of anthranilate synthase
DDJ31_RS07200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DDJ31_RS07200	COG1648	precorrin-2 dehydrogenase activity
DDJ31_RS07205	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DDJ31_RS07220	COG1464	Belongs to the NlpA lipoprotein family
DDJ31_RS07225	COG2011	ABC-type metal ion transport system permease component
DDJ31_RS07230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDJ31_RS07235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS07255	COG0584	glycerophosphoryl diester phosphodiesterase
DDJ31_RS07260	COG0204	Acyl-transferase
DDJ31_RS07260	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS07265	COG0477	Major facilitator Superfamily
DDJ31_RS07280	COG0165	Argininosuccinate lyase
DDJ31_RS07310	COG1438	arginine binding
DDJ31_RS07315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDJ31_RS07320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DDJ31_RS07325	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DDJ31_RS07330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DDJ31_RS07335	COG2197	response regulator
DDJ31_RS07340	COG2409	Drug exporters of the RND superfamily
DDJ31_RS07360	COG0463	Glycosyl transferase, family 2
DDJ31_RS07390	COG0697	spore germination
DDJ31_RS07400	COG1649	PFAM Uncharacterised BCR, COG1649
DDJ31_RS07430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDJ31_RS07430	COG0072	phenylalanine-tRNA ligase activity
DDJ31_RS07435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DDJ31_RS07440	COG5002	protein histidine kinase activity
DDJ31_RS07445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDJ31_RS07450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DDJ31_RS07455	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DDJ31_RS07460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DDJ31_RS07495	COG0560	Phosphoserine phosphatase
DDJ31_RS07495	COG3830	Belongs to the UPF0237 family
DDJ31_RS07500	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS07505	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS07510	COG0174	glutamine synthetase
DDJ31_RS07520	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDJ31_RS07545	COG4176	ABC-type proline glycine betaine transport system permease component
DDJ31_RS07550	COG4175	Glycine betaine
DDJ31_RS07550	COG0517	IMP dehydrogenase activity
DDJ31_RS07555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDJ31_RS07600	COG0805	protein transport
DDJ31_RS07605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDJ31_RS07635	COG0545	Peptidyl-prolyl cis-trans isomerase
DDJ31_RS07640	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DDJ31_RS07650	COG1609	Transcriptional regulator
DDJ31_RS07655	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DDJ31_RS07660	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DDJ31_RS07675	COG4122	O-methyltransferase activity
DDJ31_RS07680	COG1222	aaa ATPase
DDJ31_RS07710	COG2197	response regulator
DDJ31_RS07715	COG0747	negative chemotaxis
DDJ31_RS07720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS07725	COG1410	methionine synthase
DDJ31_RS07725	COG0646	methionine synthase
DDJ31_RS07730	COG1414	Transcriptional regulator
DDJ31_RS07735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDJ31_RS07740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DDJ31_RS07745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DDJ31_RS07755	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DDJ31_RS07760	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DDJ31_RS07770	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DDJ31_RS07770	COG0235	Class ii aldolase
DDJ31_RS07800	COG0402	S-adenosylhomocysteine deaminase activity
DDJ31_RS07805	COG2186	Transcriptional regulator
DDJ31_RS07815	COG0215	cysteine-tRNA ligase activity
DDJ31_RS07830	COG0406	alpha-ribazole phosphatase activity
DDJ31_RS07835	COG0598	Magnesium transport protein CorA
DDJ31_RS07845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS07850	COG0667	Aldo Keto reductase
DDJ31_RS07900	COG3012	SEC-C Motif Domain Protein
DDJ31_RS07905	COG2186	Transcriptional regulator
DDJ31_RS07910	COG3265	gluconokinase activity
DDJ31_RS07940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DDJ31_RS07945	COG2149	membrane
DDJ31_RS07980	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS07990	COG3876	Protein conserved in bacteria
DDJ31_RS08010	COG0789	Transcriptional regulator
DDJ31_RS08030	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS08040	COG0640	Transcriptional regulator
DDJ31_RS08070	COG2851	Citrate transporter
DDJ31_RS08075	COG1309	transcriptional regulator
DDJ31_RS08085	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DDJ31_RS08090	COG2188	Transcriptional regulator
DDJ31_RS08110	COG1595	DNA-templated transcription, initiation
DDJ31_RS08130	COG2755	lipolytic protein G-D-S-L family
DDJ31_RS08150	COG0726	polysaccharide deacetylase
DDJ31_RS08170	COG1725	Transcriptional regulator
DDJ31_RS08185	COG2226	methyltransferase
DDJ31_RS08215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDJ31_RS08220	COG0587	DNA-directed DNA polymerase activity
DDJ31_RS08255	COG1126	abc transporter atp-binding protein
DDJ31_RS08265	COG0765	amino acid transport
DDJ31_RS08285	COG1799	cell septum assembly
DDJ31_RS08290	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS08295	COG0477	Major facilitator Superfamily
DDJ31_RS08305	COG0671	phosphoesterase, PA-phosphatase related
DDJ31_RS08320	COG1652	LysM domain
DDJ31_RS08335	COG1160	GTP binding
DDJ31_RS08345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DDJ31_RS08375	COG0494	nUDIX hydrolase
DDJ31_RS08380	COG1187	pseudouridine synthase activity
DDJ31_RS08385	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DDJ31_RS08390	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DDJ31_RS08405	COG0686	Belongs to the AlaDH PNT family
DDJ31_RS08415	COG0494	nUDIX hydrolase
DDJ31_RS08420	COG0504	CTP synthase activity
DDJ31_RS08425	COG3387	PFAM Glycoside hydrolase 15-related
DDJ31_RS08435	COG0297	glycogen (starch) synthase activity
DDJ31_RS08440	COG0497	DNA recombination
DDJ31_RS08445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDJ31_RS08465	COG1120	ATPase activity
DDJ31_RS08470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS08475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS08480	COG0647	UMP catabolic process
DDJ31_RS08515	COG2094	Belongs to the DNA glycosylase MPG family
DDJ31_RS08525	COG1881	PFAM PEBP family protein
DDJ31_RS08545	COG1119	ATPase activity
DDJ31_RS08565	COG2197	response regulator
DDJ31_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS08580	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DDJ31_RS08590	COG1716	ATPase activity
DDJ31_RS08590	COG0842	Transport permease protein
DDJ31_RS08590	COG1131	(ABC) transporter
DDJ31_RS08595	COG0560	Phosphoserine phosphatase
DDJ31_RS08595	COG3830	Belongs to the UPF0237 family
DDJ31_RS08600	COG0588	phosphoglycerate mutase activity
DDJ31_RS08610	COG2807	transmembrane transport
DDJ31_RS08615	COG2186	Transcriptional regulator
DDJ31_RS08625	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DDJ31_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS08650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DDJ31_RS08670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DDJ31_RS08675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDJ31_RS08695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDJ31_RS08705	COG1063	alcohol dehydrogenase
DDJ31_RS08725	COG3387	PFAM Glycoside hydrolase 15-related
DDJ31_RS08775	COG0488	(ABC) transporter
DDJ31_RS08800	COG0235	Class ii aldolase
DDJ31_RS08820	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DDJ31_RS08825	COG1492	cobalamin metabolic process
DDJ31_RS08880	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DDJ31_RS08900	COG1126	abc transporter atp-binding protein
DDJ31_RS08905	COG0765	amino acid transport
DDJ31_RS08915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DDJ31_RS08920	COG0456	acetyltransferase
DDJ31_RS08925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDJ31_RS08930	COG1917	Cupin 2, conserved barrel domain protein
DDJ31_RS08935	COG5285	phytanoyl-CoA dioxygenase
DDJ31_RS08965	COG1414	Transcriptional regulator
DDJ31_RS08980	COG2252	PERMEase
DDJ31_RS08985	COG1595	DNA-templated transcription, initiation
DDJ31_RS08995	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DDJ31_RS09005	COG4677	pectinesterase activity
DDJ31_RS09010	COG4677	pectinesterase activity
DDJ31_RS09015	COG3866	Pectate lyase
DDJ31_RS09020	COG2755	lipolytic protein G-D-S-L family
DDJ31_RS09045	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS09050	COG1175	transmembrane transport
DDJ31_RS09065	COG1802	Transcriptional regulator
DDJ31_RS09075	COG0667	Aldo Keto reductase
DDJ31_RS09080	COG0583	DNA-binding transcription factor activity
DDJ31_RS09090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDJ31_RS09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDJ31_RS09100	COG1349	DNA-binding transcription factor activity
DDJ31_RS09115	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS09120	COG1063	alcohol dehydrogenase
DDJ31_RS09155	COG2814	Major facilitator Superfamily
DDJ31_RS09195	COG1802	Transcriptional regulator
DDJ31_RS09215	COG2171	N-acyltransferase activity
DDJ31_RS09220	COG3226	Transcriptional regulator
DDJ31_RS09225	COG2076	Multidrug Resistance protein
DDJ31_RS09235	COG2151	metal-sulfur cluster biosynthetic enzyme
DDJ31_RS09240	COG0822	iron-sulfur transferase activity
DDJ31_RS09245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDJ31_RS09250	COG0396	ATPase activity
DDJ31_RS09260	COG0719	Fe-S assembly protein
DDJ31_RS09275	COG2746	aminoglycoside 3-N-acetyltransferase activity
DDJ31_RS09280	COG1131	(ABC) transporter
DDJ31_RS09290	COG1612	heme a metabolic process
DDJ31_RS09300	COG0109	protoheme IX farnesyltransferase activity
DDJ31_RS09310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDJ31_RS09325	COG0363	glucosamine-6-phosphate deaminase activity
DDJ31_RS09330	COG0166	Belongs to the GPI family
DDJ31_RS09345	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDJ31_RS09350	COG0149	triose-phosphate isomerase activity
DDJ31_RS09355	COG0126	phosphoglycerate kinase activity
DDJ31_RS09360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DDJ31_RS09370	COG1481	regulation of sporulation
DDJ31_RS09380	COG1660	Displays ATPase and GTPase activities
DDJ31_RS09385	COG0322	excinuclease ABC activity
DDJ31_RS09395	COG4585	Histidine kinase
DDJ31_RS09400	COG2198	Histidine kinase
DDJ31_RS09400	COG5002	protein histidine kinase activity
DDJ31_RS09400	COG0784	Response regulator, receiver
DDJ31_RS09415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDJ31_RS09430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDJ31_RS09435	COG0765	amino acid transport
DDJ31_RS09445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DDJ31_RS09450	COG0477	Major facilitator Superfamily
DDJ31_RS09455	COG0387	Pfam Sodium calcium exchanger
DDJ31_RS09475	COG0556	nucleotide-excision repair
DDJ31_RS09485	COG0584	glycerophosphoryl diester phosphodiesterase
DDJ31_RS09490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDJ31_RS09495	COG1063	alcohol dehydrogenase
DDJ31_RS09505	COG2313	pseudouridylate synthase activity
DDJ31_RS09510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DDJ31_RS09510	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DDJ31_RS09515	COG2226	methyltransferase
DDJ31_RS09520	COG0598	Magnesium transport protein CorA
DDJ31_RS09620	COG1953	Uracil, thiamine, allantoin
DDJ31_RS09625	COG1802	Transcriptional regulator
DDJ31_RS09655	COG0237	dephospho-CoA kinase activity
DDJ31_RS09675	COG1643	Atp-dependent helicase
DDJ31_RS09715	COG2050	protein possibly involved in aromatic compounds catabolism
DDJ31_RS09770	COG0737	Belongs to the 5'-nucleotidase family
DDJ31_RS09795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDJ31_RS09835	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS09840	COG0287	Prephenate dehydrogenase
DDJ31_RS09840	COG1605	Chorismate mutase
DDJ31_RS09860	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS09870	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDJ31_RS09870	COG1024	Enoyl-CoA hydratase
DDJ31_RS09895	COG0183	Belongs to the thiolase family
DDJ31_RS09900	COG1309	transcriptional regulator
DDJ31_RS09905	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS09910	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS09920	COG2304	oxidoreductase activity
DDJ31_RS09935	COG0069	glutamate synthase activity
DDJ31_RS09935	COG0070	glutamate synthase
DDJ31_RS09935	COG0067	glutamate synthase
DDJ31_RS09965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDJ31_RS09975	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DDJ31_RS09985	COG0159	tryptophan synthase activity
DDJ31_RS09990	COG0133	tryptophan synthase activity
DDJ31_RS10000	COG0134	indole-3-glycerol-phosphate synthase activity
DDJ31_RS10015	COG2188	Transcriptional regulator
DDJ31_RS10025	COG2376	Dihydroxyacetone kinase
DDJ31_RS10040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DDJ31_RS10050	COG0107	imidazoleglycerol-phosphate synthase activity
DDJ31_RS10055	COG0251	oxidation-reduction process
DDJ31_RS10060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DDJ31_RS10065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DDJ31_RS10075	COG0131	Imidazoleglycerol-phosphate dehydratase
DDJ31_RS10080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDJ31_RS10085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DDJ31_RS10105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDJ31_RS10125	COG1432	Conserved Protein
DDJ31_RS10135	COG0587	DNA-directed DNA polymerase activity
DDJ31_RS10185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DDJ31_RS10195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DDJ31_RS10200	COG3599	regulation of cell shape
DDJ31_RS10210	COG1799	cell septum assembly
DDJ31_RS10225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DDJ31_RS10230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DDJ31_RS10235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDJ31_RS10245	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DDJ31_RS10250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DDJ31_RS10260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDJ31_RS10275	COG0275	rRNA processing
DDJ31_RS10285	COG0714	Associated with various cellular activities
DDJ31_RS10305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DDJ31_RS10315	COG1309	transcriptional regulator
DDJ31_RS10340	COG0352	thiamine-phosphate diphosphorylase activity
DDJ31_RS10355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDJ31_RS10355	COG2022	thiamine diphosphate biosynthetic process
DDJ31_RS10365	COG2022	thiamine diphosphate biosynthetic process
DDJ31_RS10370	COG2815	serine threonine protein kinase
DDJ31_RS10370	COG0515	serine threonine protein kinase
DDJ31_RS10375	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DDJ31_RS10380	COG2193	ferroxidase activity
DDJ31_RS10385	COG0243	molybdopterin cofactor binding
DDJ31_RS10390	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DDJ31_RS10405	COG0205	6-phosphofructokinase activity
DDJ31_RS10415	COG4585	Histidine kinase
DDJ31_RS10440	COG1940	carbohydrate kinase activity
DDJ31_RS10450	COG0003	Pfam Anion-transporting ATPase
DDJ31_RS10490	COG0791	NLP P60 protein
DDJ31_RS10490	COG0741	lytic transglycosylase activity
DDJ31_RS10520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDJ31_RS10525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DDJ31_RS10530	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DDJ31_RS10535	COG0723	plastoquinol--plastocyanin reductase activity
DDJ31_RS10540	COG2010	Cytochrome c
DDJ31_RS10545	COG1845	cytochrome c oxidase, subunit III
DDJ31_RS10555	COG1376	ErfK ybiS ycfS ynhG family protein
DDJ31_RS10565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DDJ31_RS10570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DDJ31_RS10580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDJ31_RS10600	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DDJ31_RS10605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DDJ31_RS10610	COG2197	response regulator
DDJ31_RS10640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDJ31_RS10660	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DDJ31_RS10665	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DDJ31_RS10665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDJ31_RS10680	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DDJ31_RS10690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DDJ31_RS10695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDJ31_RS10700	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDJ31_RS10710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DDJ31_RS10760	COG0321	lipoyl(octanoyl) transferase activity
DDJ31_RS10765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DDJ31_RS10795	COG0501	Belongs to the peptidase M48B family
DDJ31_RS10830	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS10875	COG1309	transcriptional regulator
DDJ31_RS10910	COG0366	Alpha amylase catalytic
DDJ31_RS10915	COG3833	ABC-type maltose transport systems, permease component
DDJ31_RS10920	COG1175	transmembrane transport
DDJ31_RS10925	COG2182	Extracellular solute-binding protein
DDJ31_RS10930	COG1609	Transcriptional regulator
DDJ31_RS10940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DDJ31_RS10945	COG3511	phospholipase C
DDJ31_RS10960	COG0174	glutamine synthetase
DDJ31_RS10980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDJ31_RS10980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDJ31_RS10995	COG2814	Major facilitator Superfamily
DDJ31_RS11010	COG0477	Major facilitator Superfamily
DDJ31_RS11015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DDJ31_RS11035	COG1994	Peptidase M50
DDJ31_RS11095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS11100	COG1120	ATPase activity
DDJ31_RS11110	COG2837	iron assimilation
DDJ31_RS11115	COG0672	)-iron permease
DDJ31_RS11130	COG1309	transcriptional regulator
DDJ31_RS11140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDJ31_RS11145	COG2814	Major facilitator Superfamily
DDJ31_RS11170	COG1136	(ABC) transporter
DDJ31_RS11180	COG2259	Doxx family
DDJ31_RS11270	COG3022	response to hydroperoxide
DDJ31_RS11275	COG0800	Aldolase
DDJ31_RS11290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DDJ31_RS11305	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS11315	COG2030	dehydratase
DDJ31_RS11330	COG2197	response regulator
DDJ31_RS11345	COG0477	Major facilitator Superfamily
DDJ31_RS11355	COG2247	cell wall binding repeat
DDJ31_RS11355	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDJ31_RS11415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS11440	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS11445	COG1309	transcriptional regulator
DDJ31_RS11480	COG3845	ABC transporter
DDJ31_RS11495	COG3619	membrane
DDJ31_RS11500	COG2124	cytochrome p450
DDJ31_RS11505	COG0183	Belongs to the thiolase family
DDJ31_RS11520	COG0477	Major facilitator Superfamily
DDJ31_RS11530	COG4122	O-methyltransferase activity
DDJ31_RS11565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS11585	COG2259	Doxx family
DDJ31_RS11650	COG1358	cellular component organization or biogenesis
DDJ31_RS11695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DDJ31_RS11700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDJ31_RS11710	COG0477	Major facilitator Superfamily
DDJ31_RS11715	COG1309	transcriptional regulator
DDJ31_RS11730	COG0789	Transcriptional regulator
DDJ31_RS11745	COG1741	Belongs to the pirin family
DDJ31_RS11760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDJ31_RS11765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDJ31_RS11770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDJ31_RS11815	COG1764	response to oxidative stress
DDJ31_RS11820	COG2130	NADP-dependent
DDJ31_RS11860	COG4214	carbohydrate transport
DDJ31_RS11870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDJ31_RS11880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDJ31_RS11890	COG0730	response to heat
DDJ31_RS11950	COG3386	PFAM SMP-30 Gluconolaconase
DDJ31_RS11955	COG1414	Transcriptional regulator
DDJ31_RS11975	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS11980	COG1404	Belongs to the peptidase S8 family
DDJ31_RS11985	COG1077	Cell shape determining protein MreB Mrl
DDJ31_RS12030	COG1070	Carbohydrate kinase
DDJ31_RS12045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDJ31_RS12050	COG0358	DNA primase activity
DDJ31_RS12060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DDJ31_RS12075	COG2949	membrane
DDJ31_RS12090	COG0431	NADPH-dependent FMN reductase
DDJ31_RS12135	COG0574	Belongs to the PEP-utilizing enzyme family
DDJ31_RS12135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDJ31_RS12140	COG1940	carbohydrate kinase activity
DDJ31_RS12140	COG1846	Transcriptional regulator
DDJ31_RS12220	COG0346	lactoylglutathione lyase activity
DDJ31_RS12240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDJ31_RS12280	COG0667	Aldo Keto reductase
DDJ31_RS12290	COG0423	glycine-tRNA ligase activity
DDJ31_RS12295	COG0803	Belongs to the bacterial solute-binding protein 9 family
DDJ31_RS12295	COG3443	Belongs to the bacterial solute-binding protein 9 family
DDJ31_RS12300	COG1121	(ABC) transporter
DDJ31_RS12305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDJ31_RS12320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDJ31_RS12325	COG1381	Involved in DNA repair and RecF pathway recombination
DDJ31_RS12340	COG0747	negative chemotaxis
DDJ31_RS12355	COG4608	Belongs to the ABC transporter superfamily
DDJ31_RS12360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDJ31_RS12375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDJ31_RS12390	COG2723	6-phospho-beta-galactosidase activity
DDJ31_RS12395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDJ31_RS12425	COG2315	Protein conserved in bacteria
DDJ31_RS12435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DDJ31_RS12455	COG4948	Mandelate Racemase Muconate Lactonizing
DDJ31_RS12460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDJ31_RS12475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDJ31_RS12480	COG1234	tRNA 3'-trailer cleavage
DDJ31_RS12485	COG0537	adenosine 5'-monophosphoramidase activity
DDJ31_RS12490	COG0793	Belongs to the peptidase S41A family
DDJ31_RS12490	COG4946	Tricorn protease homolog
DDJ31_RS12510	COG0484	heat shock protein binding
DDJ31_RS12515	COG1420	regulation of RNA biosynthetic process
DDJ31_RS12520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDJ31_RS12540	COG0784	Response regulator, receiver
DDJ31_RS12540	COG2205	protein histidine kinase activity
DDJ31_RS12555	COG0481	GTPase activity
DDJ31_RS12560	COG0268	Binds directly to 16S ribosomal RNA
DDJ31_RS12580	COG2353	YceI-like domain
DDJ31_RS12590	COG1555	photosystem II stabilization
DDJ31_RS12595	COG1307	EDD domain protein, DegV family
DDJ31_RS12605	COG0495	leucyl-tRNA aminoacylation
DDJ31_RS12615	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DDJ31_RS12645	COG0588	phosphoglycerate mutase activity
DDJ31_RS12650	COG0799	negative regulation of ribosome biogenesis
DDJ31_RS12660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DDJ31_RS12675	COG0501	Belongs to the peptidase M48B family
DDJ31_RS12690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DDJ31_RS12700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DDJ31_RS12710	COG1216	Glycosyl transferase, family 2
DDJ31_RS12730	COG3540	Alkaline phosphatase
DDJ31_RS12735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DDJ31_RS12740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DDJ31_RS12745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DDJ31_RS12750	COG1530	ribonuclease E activity
DDJ31_RS12775	COG0772	Belongs to the SEDS family
DDJ31_RS12780	COG0768	penicillin binding
DDJ31_RS12795	COG1077	Cell shape determining protein MreB Mrl
DDJ31_RS12800	COG0105	UTP biosynthetic process
DDJ31_RS12810	COG0285	dihydrofolate synthase activity
DDJ31_RS12815	COG0525	valine-tRNA ligase activity
DDJ31_RS12825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DDJ31_RS12830	COG0740	serine-type endopeptidase activity
DDJ31_RS12835	COG0740	serine-type endopeptidase activity
DDJ31_RS12840	COG0544	peptidyl-prolyl cis-trans isomerase activity
DDJ31_RS12860	COG3594	Acyltransferase
DDJ31_RS12870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDJ31_RS12880	COG4552	Acetyltransferase involved in intracellular survival and related
DDJ31_RS12895	COG1113	amino acid transport
DDJ31_RS12905	COG1113	amino acid transport
DDJ31_RS12910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DDJ31_RS12915	COG0588	phosphoglycerate mutase activity
DDJ31_RS12925	COG1653	transport
DDJ31_RS12930	COG1175	transmembrane transport
DDJ31_RS12935	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS12970	COG0584	glycerophosphoryl diester phosphodiesterase
DDJ31_RS12975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DDJ31_RS13025	COG0494	nUDIX hydrolase
DDJ31_RS13060	COG0697	spore germination
DDJ31_RS13070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDJ31_RS13100	COG0668	transmembrane transport
DDJ31_RS13110	COG1653	transport
DDJ31_RS13115	COG1175	transmembrane transport
DDJ31_RS13120	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS13125	COG1486	melibiose metabolic process
DDJ31_RS13145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDJ31_RS13175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDJ31_RS13305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDJ31_RS13310	COG1518	maintenance of DNA repeat elements
DDJ31_RS13435	COG0105	UTP biosynthetic process
DDJ31_RS13590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DDJ31_RS13750	COG0714	Associated with various cellular activities
DDJ31_RS13830	COG0159	tryptophan synthase activity
DDJ31_RS13875	COG2304	oxidoreductase activity
DDJ31_RS13915	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS13940	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS14000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DDJ31_RS14010	COG1131	(ABC) transporter
DDJ31_RS14020	COG3962	Belongs to the TPP enzyme family
DDJ31_RS14025	COG3718	enzyme involved in inositol metabolism
DDJ31_RS14035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDJ31_RS14040	COG1312	Catalyzes the dehydration of D-mannonate
DDJ31_RS14050	COG1063	alcohol dehydrogenase
DDJ31_RS14085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDJ31_RS14125	COG1129	ABC transporter
DDJ31_RS14135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDJ31_RS14140	COG1869	D-ribose catabolic process
DDJ31_RS14160	COG1234	tRNA 3'-trailer cleavage
DDJ31_RS14195	COG0673	inositol 2-dehydrogenase activity
DDJ31_RS14200	COG1609	Transcriptional regulator
DDJ31_RS14210	COG2197	response regulator
DDJ31_RS14215	COG4585	Histidine kinase
DDJ31_RS14230	COG1846	Transcriptional regulator
DDJ31_RS14230	COG0456	acetyltransferase
DDJ31_RS14250	COG1472	Belongs to the glycosyl hydrolase 3 family
DDJ31_RS14285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DDJ31_RS14290	COG2356	endonuclease I
DDJ31_RS14310	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
DDJ31_RS14315	COG0028	Belongs to the TPP enzyme family
DDJ31_RS14325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDJ31_RS14340	COG1946	Acyl-CoA thioesterase
DDJ31_RS14350	COG1309	transcriptional regulator
DDJ31_RS14355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDJ31_RS14370	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS14375	COG3409	Peptidoglycan-binding domain 1 protein
DDJ31_RS14405	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DDJ31_RS14440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDJ31_RS14445	COG0589	response to stress
DDJ31_RS14455	COG4977	sequence-specific DNA binding
DDJ31_RS14460	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DDJ31_RS14475	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
DDJ31_RS14505	COG3979	chitinase
DDJ31_RS14515	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS14565	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DDJ31_RS14595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS14610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDJ31_RS14630	COG0765	amino acid transport
DDJ31_RS14635	COG0765	amino acid transport
DDJ31_RS14640	COG1126	abc transporter atp-binding protein
DDJ31_RS14655	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS14660	COG3397	chitin binding
DDJ31_RS14680	COG2186	Transcriptional regulator
DDJ31_RS14740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS14745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDJ31_RS14750	COG2188	Transcriptional regulator
DDJ31_RS14760	COG1940	carbohydrate kinase activity
DDJ31_RS14765	COG0673	inositol 2-dehydrogenase activity
DDJ31_RS14770	COG4702	Belongs to the UPF0303 family
DDJ31_RS14835	COG3764	Sortase (surface protein transpeptidase)
DDJ31_RS14850	COG0556	nucleotide-excision repair
DDJ31_RS14895	COG2733	membrane
DDJ31_RS14925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDJ31_RS14955	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DDJ31_RS14965	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DDJ31_RS14970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ31_RS14975	COG1263	PTS System
DDJ31_RS14980	COG1263	PTS System
DDJ31_RS14985	COG1234	tRNA 3'-trailer cleavage
DDJ31_RS15010	COG1113	amino acid transport
DDJ31_RS15020	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DDJ31_RS15030	COG1335	isochorismatase
DDJ31_RS15085	COG0277	FAD linked oxidase domain protein
DDJ31_RS15100	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DDJ31_RS15110	COG1174	glycine betaine transport
DDJ31_RS15120	COG1174	glycine betaine transport
DDJ31_RS15130	COG3480	Lon protease (S16) C-terminal proteolytic domain
DDJ31_RS15215	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DDJ31_RS15220	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS15240	COG1678	Uncharacterized ACR, COG1678
DDJ31_RS15245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDJ31_RS15250	COG0776	regulation of translation
DDJ31_RS15260	COG3973	AAA domain
DDJ31_RS15300	COG0583	DNA-binding transcription factor activity
DDJ31_RS15315	COG1175	transmembrane transport
DDJ31_RS15320	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS15325	COG1501	Belongs to the glycosyl hydrolase 31 family
DDJ31_RS15340	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DDJ31_RS15345	COG0793	Belongs to the peptidase S41A family
DDJ31_RS15355	COG2884	Cell division ATP-binding protein ftsE
DDJ31_RS15370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DDJ31_RS15375	COG0515	serine threonine protein kinase
DDJ31_RS15380	COG0515	serine threonine protein kinase
DDJ31_RS15390	COG1653	transport
DDJ31_RS15395	COG1175	transmembrane transport
DDJ31_RS15400	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS15405	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DDJ31_RS15410	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DDJ31_RS15415	COG1216	Glycosyl transferase, family 2
DDJ31_RS15435	COG1764	response to oxidative stress
DDJ31_RS15440	COG1846	Transcriptional regulator
DDJ31_RS15475	COG1134	teichoic acid transport
DDJ31_RS15485	COG0477	Major facilitator Superfamily
DDJ31_RS15495	COG2902	Dehydrogenase
DDJ31_RS15520	COG0653	protein targeting
DDJ31_RS15530	COG3214	Protein conserved in bacteria
DDJ31_RS15535	COG2197	response regulator
DDJ31_RS15540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DDJ31_RS15550	COG0823	Involved in the tonB-independent uptake of proteins
DDJ31_RS15555	COG5000	phosphorelay sensor kinase activity
DDJ31_RS15555	COG5002	protein histidine kinase activity
DDJ31_RS15560	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS15565	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DDJ31_RS15585	COG0714	Associated with various cellular activities
DDJ31_RS15625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DDJ31_RS15635	COG1482	cell wall glycoprotein biosynthetic process
DDJ31_RS15645	COG2835	tetraacyldisaccharide 4'-kinase activity
DDJ31_RS15650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDJ31_RS15655	COG1620	l-lactate permease
DDJ31_RS15690	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DDJ31_RS15695	COG0778	Nitroreductase
DDJ31_RS15695	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DDJ31_RS15730	COG1316	TRANSCRIPTIONal
DDJ31_RS15745	COG1316	TRANSCRIPTIONal
DDJ31_RS15750	COG1316	TRANSCRIPTIONal
DDJ31_RS15765	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DDJ31_RS15800	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DDJ31_RS15815	COG2205	protein histidine kinase activity
DDJ31_RS15820	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS15825	COG3104	oligopeptide transport
DDJ31_RS15860	COG1366	Belongs to the anti-sigma-factor antagonist family
DDJ31_RS15865	COG1191	sigma factor activity
DDJ31_RS15870	COG1228	amidohydrolase
DDJ31_RS15885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DDJ31_RS15925	COG2986	histidine ammonia-lyase
DDJ31_RS15930	COG0288	reversible hydration of carbon dioxide
DDJ31_RS15935	COG0659	secondary active sulfate transmembrane transporter activity
DDJ31_RS15950	COG2755	lipolytic protein G-D-S-L family
DDJ31_RS15955	COG0183	Belongs to the thiolase family
DDJ31_RS15990	COG1136	(ABC) transporter
DDJ31_RS15990	COG0577	efflux transmembrane transporter activity
DDJ31_RS15995	COG0577	efflux transmembrane transporter activity
DDJ31_RS16000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDJ31_RS16005	COG1252	NADH dehydrogenase
DDJ31_RS16025	COG0148	phosphopyruvate hydratase activity
DDJ31_RS16040	COG2124	cytochrome p450
DDJ31_RS16060	COG0515	serine threonine protein kinase
DDJ31_RS16060	COG2815	serine threonine protein kinase
DDJ31_RS16090	COG1136	(ABC) transporter
DDJ31_RS16095	COG0477	Major facilitator Superfamily
DDJ31_RS16125	COG4585	Histidine kinase
DDJ31_RS16140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DDJ31_RS16145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DDJ31_RS16150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DDJ31_RS16155	COG0193	aminoacyl-tRNA hydrolase activity
DDJ31_RS16165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DDJ31_RS16175	COG1309	transcriptional regulator
DDJ31_RS16185	COG4106	trans-aconitate 2-methyltransferase activity
DDJ31_RS16195	COG2197	response regulator
DDJ31_RS16230	COG0641	radical SAM
DDJ31_RS16245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DDJ31_RS16285	COG0488	(ABC) transporter
DDJ31_RS16290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DDJ31_RS16295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDJ31_RS16305	COG0084	hydrolase, TatD family'
DDJ31_RS16340	COG0310	cobalt ion transport
DDJ31_RS16350	COG1122	ATPase activity
DDJ31_RS16355	COG0456	acetyltransferase
DDJ31_RS16370	COG0442	prolyl-tRNA aminoacylation
DDJ31_RS16375	COG2226	methyltransferase
DDJ31_RS16380	COG2409	Drug exporters of the RND superfamily
DDJ31_RS16390	COG4946	Tricorn protease homolog
DDJ31_RS16390	COG0793	Belongs to the peptidase S41A family
DDJ31_RS16400	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS16405	COG2267	carboxylic ester hydrolase activity
DDJ31_RS16410	COG2072	flavoprotein involved in K transport
DDJ31_RS16445	COG0315	cyclic pyranopterin monophosphate synthase activity
DDJ31_RS16445	COG0521	Mo-molybdopterin cofactor biosynthetic process
DDJ31_RS16450	COG0315	cyclic pyranopterin monophosphate synthase activity
DDJ31_RS16460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDJ31_RS16465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDJ31_RS16475	COG3263	regulation of cellular component size
DDJ31_RS16490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DDJ31_RS16500	COG1970	mechanosensitive ion channel activity
DDJ31_RS16520	COG3191	aminopeptidase activity
DDJ31_RS16535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ31_RS16535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ31_RS16535	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DDJ31_RS16545	COG1349	DNA-binding transcription factor activity
DDJ31_RS16550	COG0477	Major facilitator Superfamily
DDJ31_RS16570	COG3384	dioxygenase
DDJ31_RS16575	COG1846	Transcriptional regulator
DDJ31_RS16610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDJ31_RS16650	COG0529	Catalyzes the synthesis of activated sulfate
DDJ31_RS16650	COG2046	Belongs to the sulfate adenylyltransferase family
DDJ31_RS16680	COG1175	transmembrane transport
DDJ31_RS16685	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS16700	COG0386	Belongs to the glutathione peroxidase family
DDJ31_RS16715	COG1686	Belongs to the peptidase S11 family
DDJ31_RS16760	COG1476	TRANSCRIPTIONal
DDJ31_RS16795	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DDJ31_RS16815	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS16820	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DDJ31_RS16870	COG1024	Enoyl-CoA hydratase
DDJ31_RS16885	COG0667	Aldo Keto reductase
DDJ31_RS16895	COG0515	serine threonine protein kinase
DDJ31_RS16895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDJ31_RS16905	COG1309	transcriptional regulator
DDJ31_RS16935	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS16955	COG0259	pyridoxamine-phosphate oxidase activity
DDJ31_RS16975	COG2072	flavoprotein involved in K transport
DDJ31_RS16980	COG0045	succinate-CoA ligase (ADP-forming) activity
DDJ31_RS16985	COG1024	Enoyl-CoA hydratase
DDJ31_RS16995	COG0747	negative chemotaxis
DDJ31_RS17010	COG4172	Belongs to the ABC transporter superfamily
DDJ31_RS17040	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS17045	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS17060	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS17065	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS17075	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS17140	COG0596	Alpha beta hydrolase
DDJ31_RS17140	COG2945	thiolester hydrolase activity
DDJ31_RS17150	COG4821	SIS domain
DDJ31_RS17170	COG5002	protein histidine kinase activity
DDJ31_RS17175	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS17225	COG0259	pyridoxamine-phosphate oxidase activity
DDJ31_RS17240	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS17255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDJ31_RS17285	COG5006	permease, DMT superfamily
DDJ31_RS17300	COG2172	sigma factor antagonist activity
DDJ31_RS17305	COG0277	FAD linked oxidase domain protein
DDJ31_RS17310	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DDJ31_RS17315	COG0384	phenazine biosynthesis protein PhzF
DDJ31_RS17360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDJ31_RS17370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DDJ31_RS17390	COG0667	Aldo Keto reductase
DDJ31_RS17410	COG2252	PERMEase
DDJ31_RS17420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDJ31_RS17440	COG2814	Major facilitator Superfamily
DDJ31_RS17450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DDJ31_RS17455	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DDJ31_RS17460	COG1278	Cold shock
DDJ31_RS17485	COG3973	AAA domain
DDJ31_RS17495	COG1061	Type III restriction enzyme res subunit
DDJ31_RS17525	COG1737	Transcriptional regulator
DDJ31_RS17530	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DDJ31_RS17535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ31_RS17535	COG1263	PTS System
DDJ31_RS17560	COG1051	belongs to the nudix hydrolase family
DDJ31_RS17565	COG0459	protein refolding
DDJ31_RS17570	COG1278	Cold shock
DDJ31_RS17585	COG0463	Glycosyl transferase, family 2
DDJ31_RS17590	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DDJ31_RS17615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DDJ31_RS17620	COG1105	Belongs to the carbohydrate kinase PfkB family
DDJ31_RS17630	COG5001	Diguanylate cyclase
DDJ31_RS17630	COG3300	MHYT domain
DDJ31_RS17715	COG0723	plastoquinol--plastocyanin reductase activity
DDJ31_RS17715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDJ31_RS17745	COG3903	Transcriptional regulator
DDJ31_RS17745	COG3629	intracellular signal transduction
DDJ31_RS17750	COG3629	intracellular signal transduction
DDJ31_RS17750	COG3903	Transcriptional regulator
DDJ31_RS17795	COG0791	NLP P60 protein
DDJ31_RS17885	COG3842	ATPase activity
DDJ31_RS17905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDJ31_RS17910	COG0215	cysteine-tRNA ligase activity
DDJ31_RS17915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DDJ31_RS17920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DDJ31_RS17925	COG1329	Transcriptional regulator
DDJ31_RS17940	COG5002	protein histidine kinase activity
DDJ31_RS17955	COG4249	Peptidase C14 caspase catalytic subunit p20
DDJ31_RS17955	COG2319	Wd-40 repeat
DDJ31_RS17980	COG2188	Transcriptional regulator
DDJ31_RS17990	COG0588	phosphoglycerate mutase activity
DDJ31_RS18045	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS18145	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS18190	COG0546	phosphoglycolate phosphatase activity
DDJ31_RS18200	COG2188	Transcriptional regulator
DDJ31_RS18205	COG4552	Acetyltransferase involved in intracellular survival and related
DDJ31_RS18220	COG1490	D-aminoacyl-tRNA deacylase activity
DDJ31_RS18225	COG0354	folic acid binding
DDJ31_RS18230	COG0735	belongs to the Fur family
DDJ31_RS18235	COG3485	protocatechuate 3,4-dioxygenase
DDJ31_RS18290	COG2897	thiosulfate sulfurtransferase activity
DDJ31_RS18315	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS18320	COG1609	Transcriptional regulator
DDJ31_RS18325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDJ31_RS18330	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS18340	COG1132	(ABC) transporter
DDJ31_RS18345	COG0737	Belongs to the 5'-nucleotidase family
DDJ31_RS18350	COG0456	acetyltransferase
DDJ31_RS18380	COG1725	Transcriptional regulator
DDJ31_RS18385	COG1131	(ABC) transporter
DDJ31_RS18400	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DDJ31_RS18430	COG1937	Protein conserved in bacteria
DDJ31_RS18440	COG0306	phosphate transporter
DDJ31_RS18445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDJ31_RS18465	COG0277	FAD linked oxidase domain protein
DDJ31_RS18470	COG0671	phosphoesterase, PA-phosphatase related
DDJ31_RS18475	COG0739	heme binding
DDJ31_RS18475	COG0741	lytic transglycosylase activity
DDJ31_RS18475	COG1196	nuclear chromosome segregation
DDJ31_RS18560	COG1252	NADH dehydrogenase
DDJ31_RS18570	COG1470	cell adhesion involved in biofilm formation
DDJ31_RS18570	COG0366	Alpha amylase catalytic
DDJ31_RS18585	COG0579	oxidoreductase
DDJ31_RS18590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDJ31_RS18600	COG0667	Aldo Keto reductase
DDJ31_RS18625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDJ31_RS18625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDJ31_RS18635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDJ31_RS18650	COG0509	glycine decarboxylation via glycine cleavage system
DDJ31_RS18680	COG0513	Belongs to the DEAD box helicase family
DDJ31_RS18720	COG1643	Atp-dependent helicase
DDJ31_RS18755	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DDJ31_RS18785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDJ31_RS18790	COG0047	phosphoribosylformylglycinamidine synthase activity
DDJ31_RS18795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDJ31_RS18830	COG2197	response regulator
DDJ31_RS18840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDJ31_RS18855	COG0151	Belongs to the GarS family
DDJ31_RS18925	COG0433	COG0433 Predicted ATPase
DDJ31_RS18940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DDJ31_RS18975	COG1191	sigma factor activity
DDJ31_RS18980	COG1191	sigma factor activity
DDJ31_RS19000	COG0477	Major facilitator Superfamily
DDJ31_RS19005	COG2353	YceI-like domain
DDJ31_RS19010	COG3467	pyridoxamine 5'-phosphate
DDJ31_RS19020	COG0477	Major facilitator Superfamily
DDJ31_RS19025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DDJ31_RS19035	COG2205	protein histidine kinase activity
DDJ31_RS19040	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS19070	COG2271	Major facilitator Superfamily
DDJ31_RS19090	COG0784	Response regulator, receiver
DDJ31_RS19095	COG1309	transcriptional regulator
DDJ31_RS19100	COG2814	Major facilitator Superfamily
DDJ31_RS19105	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS19110	COG1595	DNA-templated transcription, initiation
DDJ31_RS19150	COG2197	response regulator
DDJ31_RS19180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDJ31_RS19195	COG0653	protein targeting
DDJ31_RS19215	COG0006	proline dipeptidase activity
DDJ31_RS19220	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DDJ31_RS19240	COG1999	signal sequence binding
DDJ31_RS19255	COG2837	iron assimilation
DDJ31_RS19265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DDJ31_RS19270	COG0561	phosphatase activity
DDJ31_RS19310	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DDJ31_RS19320	COG0561	phosphatase activity
DDJ31_RS19325	COG0741	lytic transglycosylase activity
DDJ31_RS19325	COG0739	heme binding
DDJ31_RS19325	COG1196	nuclear chromosome segregation
DDJ31_RS19335	COG4988	ABC transporter
DDJ31_RS19340	COG1294	oxidase, subunit
DDJ31_RS19345	COG1271	oxidase subunit
DDJ31_RS19350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDJ31_RS19355	COG1609	Transcriptional regulator
DDJ31_RS19380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DDJ31_RS19405	COG0662	Cupin 2, conserved barrel domain protein
DDJ31_RS19410	COG1950	PFAM Membrane protein of
DDJ31_RS19415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDJ31_RS19420	COG0626	cystathionine gamma-synthase activity
DDJ31_RS19435	COG1017	nitric oxide dioxygenase activity
DDJ31_RS19435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDJ31_RS19485	COG0305	Participates in initiation and elongation during chromosome replication
DDJ31_RS19495	COG0359	binds to the 23S rRNA
DDJ31_RS19500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DDJ31_RS19505	COG0629	single-stranded DNA binding
DDJ31_RS19510	COG0360	Binds together with S18 to 16S ribosomal RNA
DDJ31_RS19545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDJ31_RS19570	COG0617	tRNA 3'-terminal CCA addition
DDJ31_RS19585	COG0515	serine threonine protein kinase
DDJ31_RS19585	COG2815	serine threonine protein kinase
DDJ31_RS19590	COG1595	DNA-templated transcription, initiation
DDJ31_RS19600	COG0492	ferredoxin-NADP+ reductase activity
DDJ31_RS19605	COG3118	belongs to the thioredoxin family
DDJ31_RS19620	COG1192	Involved in chromosome partitioning
DDJ31_RS19625	COG0357	Ribosomal RNA small subunit methyltransferase G
DDJ31_RS19635	COG0706	membrane insertase activity
DDJ31_RS19640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DDJ31_RS19645	COG0594	ribonuclease P activity
DDJ31_RS19650	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DDJ31_RS19655	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DDJ31_RS19660	COG0592	DNA-directed DNA polymerase activity
DDJ31_RS19665	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DDJ31_RS19670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DDJ31_RS19675	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DDJ31_RS19680	COG0187	DNA topoisomerase II activity
DDJ31_RS19685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDJ31_RS19745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DDJ31_RS19770	COG0515	serine threonine protein kinase
DDJ31_RS19800	COG0705	Rhomboid family
DDJ31_RS19815	COG3764	Sortase (surface protein transpeptidase)
DDJ31_RS19830	COG3764	Sortase (surface protein transpeptidase)
DDJ31_RS19835	COG3764	Sortase (surface protein transpeptidase)
DDJ31_RS19840	COG0515	serine threonine protein kinase
DDJ31_RS19845	COG0768	penicillin binding
DDJ31_RS19860	COG1716	ATPase activity
DDJ31_RS19865	COG1716	ATPase activity
DDJ31_RS19875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DDJ31_RS19880	COG1733	regulation of RNA biosynthetic process
DDJ31_RS19905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDJ31_RS19910	COG2151	metal-sulfur cluster biosynthetic enzyme
DDJ31_RS19915	COG3396	Phenylacetate-CoA oxygenase
DDJ31_RS19920	COG3460	Phenylacetate-CoA oxygenase
DDJ31_RS19925	COG3396	Phenylacetate-CoA oxygenase
DDJ31_RS19950	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDJ31_RS19955	COG1309	transcriptional regulator
DDJ31_RS19960	COG1522	sequence-specific DNA binding
DDJ31_RS19995	COG0604	alcohol dehydrogenase
DDJ31_RS20010	COG0515	serine threonine protein kinase
DDJ31_RS20015	COG0515	serine threonine protein kinase
DDJ31_RS20040	COG0022	dehydrogenase e1 component
DDJ31_RS20045	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDJ31_RS20085	COG1362	aminopeptidase activity
DDJ31_RS20090	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS20100	COG1741	Belongs to the pirin family
DDJ31_RS20115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DDJ31_RS20135	COG3866	Pectate lyase
DDJ31_RS20180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDJ31_RS20195	COG0583	DNA-binding transcription factor activity
DDJ31_RS20205	COG1289	transmembrane transporter activity
DDJ31_RS20245	COG0604	alcohol dehydrogenase
DDJ31_RS20265	COG1957	nucleoside hydrolase
DDJ31_RS20270	COG0667	Aldo Keto reductase
DDJ31_RS20280	COG0366	Alpha amylase catalytic
DDJ31_RS20340	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DDJ31_RS20345	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DDJ31_RS20350	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DDJ31_RS20370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DDJ31_RS20375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DDJ31_RS20390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DDJ31_RS20390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DDJ31_RS20395	COG1136	(ABC) transporter
DDJ31_RS20405	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DDJ31_RS20415	COG4585	Histidine kinase
DDJ31_RS20440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS20455	COG0513	Belongs to the DEAD box helicase family
DDJ31_RS20460	COG1278	Cold shock
DDJ31_RS20500	COG1725	Transcriptional regulator
DDJ31_RS20505	COG1131	(ABC) transporter
DDJ31_RS20525	COG2197	response regulator
DDJ31_RS20530	COG4585	Histidine kinase
DDJ31_RS20570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDJ31_RS20570	COG0515	serine threonine protein kinase
DDJ31_RS20580	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
DDJ31_RS20610	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DDJ31_RS20630	COG2181	nitrate reductase activity
DDJ31_RS20630	COG0247	lactate metabolic process
DDJ31_RS20635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DDJ31_RS20640	COG0443	Heat shock 70 kDa protein
DDJ31_RS20645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DDJ31_RS20650	COG0484	heat shock protein binding
DDJ31_RS20655	COG0789	Transcriptional regulator
DDJ31_RS20660	COG4213	ABC transporter substrate-binding protein
DDJ31_RS20695	COG0542	response to heat
DDJ31_RS20735	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DDJ31_RS20750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DDJ31_RS20755	COG0191	fructose-bisphosphate aldolase activity
DDJ31_RS20760	COG0477	Major facilitator Superfamily
DDJ31_RS20790	COG2197	response regulator
DDJ31_RS20805	COG3559	Exporter of polyketide antibiotics
DDJ31_RS20810	COG1131	(ABC) transporter
DDJ31_RS20825	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DDJ31_RS20835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DDJ31_RS20845	COG2268	Band 7 protein
DDJ31_RS20880	COG1802	Transcriptional regulator
DDJ31_RS20900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DDJ31_RS20905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DDJ31_RS20930	COG1595	DNA-templated transcription, initiation
DDJ31_RS20955	COG0701	Predicted permease
DDJ31_RS20995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DDJ31_RS21020	COG2188	Transcriptional regulator
DDJ31_RS21030	COG2188	Transcriptional regulator
DDJ31_RS21065	COG1408	metallophosphoesterase
DDJ31_RS21085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDJ31_RS21095	COG0003	Pfam Anion-transporting ATPase
DDJ31_RS21120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDJ31_RS21150	COG2267	carboxylic ester hydrolase activity
DDJ31_RS21165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDJ31_RS21230	COG1205	dead DEAH box helicase
DDJ31_RS21230	COG1111	helicase
DDJ31_RS21235	COG1366	Belongs to the anti-sigma-factor antagonist family
DDJ31_RS21240	COG2172	sigma factor antagonist activity
DDJ31_RS21245	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DDJ31_RS21265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDJ31_RS21265	COG1754	DNA topoisomerase type I activity
DDJ31_RS21270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DDJ31_RS21275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDJ31_RS21295	COG2175	clavaminate synthase activity
DDJ31_RS21305	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS21315	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS21320	COG2197	response regulator
DDJ31_RS21325	COG4585	Histidine kinase
DDJ31_RS21340	COG2030	dehydratase
DDJ31_RS21345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDJ31_RS21435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDJ31_RS21435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDJ31_RS21470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDJ31_RS21475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDJ31_RS21480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDJ31_RS21485	COG0254	rRNA binding
DDJ31_RS21495	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DDJ31_RS21515	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS21520	COG2318	DinB family
DDJ31_RS21535	COG0076	glutamate decarboxylase activity
DDJ31_RS21545	COG0393	Putative heavy-metal-binding
DDJ31_RS21560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DDJ31_RS21565	COG2027	D-alanyl-D-alanine carboxypeptidase
DDJ31_RS21575	COG0037	tRNA processing
DDJ31_RS21590	COG0302	gtp cyclohydrolase
DDJ31_RS21605	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DDJ31_RS21620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDJ31_RS21620	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DDJ31_RS21645	COG0649	NAD binding
DDJ31_RS21660	COG2197	response regulator
DDJ31_RS21680	COG0156	8-amino-7-oxononanoate synthase activity
DDJ31_RS21690	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DDJ31_RS21695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DDJ31_RS21705	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DDJ31_RS21725	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DDJ31_RS21750	COG0739	heme binding
DDJ31_RS21760	COG0477	Major facilitator Superfamily
DDJ31_RS21765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DDJ31_RS21770	COG2205	protein histidine kinase activity
DDJ31_RS21775	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS21785	COG1595	DNA-templated transcription, initiation
DDJ31_RS21800	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DDJ31_RS21820	COG0248	Ppx GppA phosphatase
DDJ31_RS21825	COG1082	Xylose isomerase domain protein TIM barrel
DDJ31_RS21835	COG0129	dihydroxy-acid dehydratase activity
DDJ31_RS21855	COG2226	methyltransferase
DDJ31_RS21860	COG0659	secondary active sulfate transmembrane transporter activity
DDJ31_RS21865	COG1129	ABC transporter
DDJ31_RS21865	COG0842	Transport permease protein
DDJ31_RS21875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDJ31_RS21880	COG1335	isochorismatase
DDJ31_RS21890	COG0180	Tryptophanyl-tRNA synthetase
DDJ31_RS21910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS21920	COG0738	Major facilitator superfamily
DDJ31_RS21925	COG0123	including yeast histone deacetylase and acetoin utilization protein
DDJ31_RS21930	COG0739	heme binding
DDJ31_RS21980	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DDJ31_RS21985	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DDJ31_RS21990	COG0181	hydroxymethylbilane synthase activity
DDJ31_RS21995	COG1648	precorrin-2 dehydrogenase activity
DDJ31_RS21995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DDJ31_RS22000	COG0113	porphobilinogen synthase activity
DDJ31_RS22010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDJ31_RS22020	COG0018	arginyl-trna synthetase
DDJ31_RS22025	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DDJ31_RS22045	COG1690	Belongs to the RtcB family
DDJ31_RS22060	COG1742	UPF0060 membrane protein
DDJ31_RS22070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS22080	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS22130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DDJ31_RS22135	COG0406	alpha-ribazole phosphatase activity
DDJ31_RS22150	COG0785	Cytochrome C biogenesis protein
DDJ31_RS22155	COG1333	cytochrome c biogenesis protein
DDJ31_RS22160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DDJ31_RS22180	COG0183	Belongs to the thiolase family
DDJ31_RS22195	COG1309	transcriptional regulator
DDJ31_RS22210	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DDJ31_RS22220	COG0163	prenyltransferase activity
DDJ31_RS22235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DDJ31_RS22245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DDJ31_RS22255	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DDJ31_RS22260	COG1674	ftsk spoiiie
DDJ31_RS22325	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
DDJ31_RS22375	COG3209	COG3209 Rhs family protein
DDJ31_RS22390	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DDJ31_RS22395	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DDJ31_RS22405	COG3979	chitinase
DDJ31_RS22425	COG2226	methyltransferase
DDJ31_RS22455	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDJ31_RS22460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDJ31_RS22465	COG0649	NAD binding
DDJ31_RS22475	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DDJ31_RS22480	COG1034	ATP synthesis coupled electron transport
DDJ31_RS22485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DDJ31_RS22490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDJ31_RS22495	COG0839	Belongs to the complex I subunit 6 family
DDJ31_RS22500	COG0713	ATP synthesis coupled electron transport
DDJ31_RS22505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DDJ31_RS22515	COG1007	ATP synthesis coupled electron transport
DDJ31_RS22520	COG0514	ATP-dependent DNA helicase (RecQ)
DDJ31_RS22535	COG2207	Transcriptional regulator
DDJ31_RS22560	COG0492	ferredoxin-NADP+ reductase activity
DDJ31_RS22565	COG0561	phosphatase activity
DDJ31_RS22580	COG3104	oligopeptide transport
DDJ31_RS22595	COG1131	(ABC) transporter
DDJ31_RS22635	COG0702	epimerase
DDJ31_RS22640	COG1733	regulation of RNA biosynthetic process
DDJ31_RS22645	COG1013	pyruvate-flavodoxin oxidoreductase activity
DDJ31_RS22650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DDJ31_RS22650	COG0674	pyruvate-flavodoxin oxidoreductase activity
DDJ31_RS22670	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDJ31_RS22680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDJ31_RS22685	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DDJ31_RS22690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDJ31_RS22700	COG0713	ATP synthesis coupled electron transport
DDJ31_RS22715	COG1007	ATP synthesis coupled electron transport
DDJ31_RS22720	COG0501	Belongs to the peptidase M48B family
DDJ31_RS22725	COG3304	Inner membrane component domain
DDJ31_RS22735	COG2261	transglycosylase associated protein
DDJ31_RS22740	COG1666	GTP binding
DDJ31_RS22760	COG0702	epimerase
DDJ31_RS22780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDJ31_RS22785	COG2030	dehydratase
DDJ31_RS22805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DDJ31_RS22815	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDJ31_RS22820	COG0436	Aminotransferase
DDJ31_RS22835	COG0250	Participates in transcription elongation, termination and antitermination
DDJ31_RS22840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DDJ31_RS22845	COG0081	regulation of translation
DDJ31_RS22855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DDJ31_RS22865	COG0085	RNA polymerase activity
DDJ31_RS22870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DDJ31_RS22880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DDJ31_RS22885	COG0049	tRNA binding
DDJ31_RS22890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDJ31_RS22895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDJ31_RS22905	COG0051	transcription antitermination factor activity, RNA binding
DDJ31_RS22910	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DDJ31_RS22915	COG0088	Forms part of the polypeptide exit tunnel
DDJ31_RS22920	COG0089	rRNA binding
DDJ31_RS22925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DDJ31_RS22930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DDJ31_RS22935	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DDJ31_RS22940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DDJ31_RS22945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DDJ31_RS22950	COG0255	Belongs to the universal ribosomal protein uL29 family
DDJ31_RS22955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DDJ31_RS22960	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DDJ31_RS22965	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DDJ31_RS22970	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DDJ31_RS22975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDJ31_RS22980	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DDJ31_RS22985	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DDJ31_RS22990	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DDJ31_RS22995	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DDJ31_RS23000	COG1841	ribosomal large subunit assembly
DDJ31_RS23005	COG0200	Binds to the 23S rRNA
DDJ31_RS23015	COG0563	adenylate kinase activity
DDJ31_RS23030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DDJ31_RS23035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDJ31_RS23040	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DDJ31_RS23045	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DDJ31_RS23050	COG0202	RNA polymerase activity
DDJ31_RS23055	COG0203	ribosomal protein L17
DDJ31_RS23060	COG0101	tRNA pseudouridine synthase activity
DDJ31_RS23075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DDJ31_RS23080	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DDJ31_RS23085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDJ31_RS23095	COG1072	(Pantothenic acid kinase))
DDJ31_RS23100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDJ31_RS23105	COG0736	holo-[acyl-carrier-protein] synthase activity
DDJ31_RS23120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DDJ31_RS23130	COG0802	atpase or kinase
DDJ31_RS23150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDJ31_RS23165	COG1609	Transcriptional regulator
DDJ31_RS23175	COG1316	TRANSCRIPTIONal
DDJ31_RS23185	COG4941	Belongs to the sigma-70 factor family
DDJ31_RS23195	COG0726	polysaccharide deacetylase
DDJ31_RS23200	COG0726	polysaccharide deacetylase
DDJ31_RS23205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DDJ31_RS23210	COG0459	protein refolding
DDJ31_RS23225	COG0583	DNA-binding transcription factor activity
DDJ31_RS23240	COG1595	DNA-templated transcription, initiation
DDJ31_RS23250	COG0516	GMP reductase activity
DDJ31_RS23260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DDJ31_RS23270	COG2815	serine threonine protein kinase
DDJ31_RS23270	COG0515	serine threonine protein kinase
DDJ31_RS23275	COG0515	serine threonine protein kinase
DDJ31_RS23275	COG2815	serine threonine protein kinase
DDJ31_RS23280	COG0515	serine threonine protein kinase
DDJ31_RS23290	COG0515	serine threonine protein kinase
DDJ31_RS23295	COG1216	Glycosyl transferase, family 2
DDJ31_RS23300	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS23325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DDJ31_RS23325	COG0519	Catalyzes the synthesis of GMP from XMP
DDJ31_RS23380	COG2197	response regulator
DDJ31_RS23420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDJ31_RS23435	COG0714	Associated with various cellular activities
DDJ31_RS23445	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DDJ31_RS23455	COG0045	succinate-CoA ligase (ADP-forming) activity
DDJ31_RS23485	COG0138	bifunctional purine biosynthesis protein purh
DDJ31_RS23500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DDJ31_RS23520	COG0039	L-malate dehydrogenase activity
DDJ31_RS23540	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS23550	COG0517	IMP dehydrogenase activity
DDJ31_RS23550	COG4175	Glycine betaine
DDJ31_RS23575	COG4221	oxidoreductase activity
DDJ31_RS23620	COG0754	glutathionylspermidine amidase activity
DDJ31_RS23625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DDJ31_RS23630	COG0180	Tryptophanyl-tRNA synthetase
DDJ31_RS23650	COG0671	phosphoesterase, PA-phosphatase related
DDJ31_RS23665	COG1295	ribonuclease BN
DDJ31_RS23680	COG1408	metallophosphoesterase
DDJ31_RS23690	COG2205	protein histidine kinase activity
DDJ31_RS23695	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS23700	COG2409	Drug exporters of the RND superfamily
DDJ31_RS23705	COG1309	transcriptional regulator
DDJ31_RS23745	COG1053	succinate dehydrogenase
DDJ31_RS23755	COG2009	succinate dehydrogenase
DDJ31_RS23765	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DDJ31_RS23800	COG4106	trans-aconitate 2-methyltransferase activity
DDJ31_RS23830	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS23835	COG4221	oxidoreductase activity
DDJ31_RS23845	COG0604	alcohol dehydrogenase
DDJ31_RS23855	COG1278	Cold shock
DDJ31_RS23860	COG0513	Belongs to the DEAD box helicase family
DDJ31_RS23880	COG1595	DNA-templated transcription, initiation
DDJ31_RS23940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DDJ31_RS23950	COG1216	Glycosyl transferase, family 2
DDJ31_RS23965	COG2089	acid synthase
DDJ31_RS23980	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DDJ31_RS23980	COG1473	amidohydrolase
DDJ31_RS23985	COG1744	ABC transporter substrate-binding protein PnrA-like
DDJ31_RS23990	COG1744	ABC transporter substrate-binding protein PnrA-like
DDJ31_RS24035	COG2814	Major facilitator Superfamily
DDJ31_RS24040	COG0583	DNA-binding transcription factor activity
DDJ31_RS24050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDJ31_RS24075	COG2205	protein histidine kinase activity
DDJ31_RS24080	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS24085	COG1595	DNA-templated transcription, initiation
DDJ31_RS24100	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS24105	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS24110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DDJ31_RS24120	COG3973	AAA domain
DDJ31_RS24130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDJ31_RS24160	COG4770	biotin carboxylase activity
DDJ31_RS24170	COG0424	maF-like protein
DDJ31_RS24180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDJ31_RS24190	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DDJ31_RS24195	COG1024	Enoyl-CoA hydratase
DDJ31_RS24205	COG2986	histidine ammonia-lyase
DDJ31_RS24235	COG1136	(ABC) transporter
DDJ31_RS24240	COG1404	Belongs to the peptidase S8 family
DDJ31_RS24250	COG1064	alcohol dehydrogenase
DDJ31_RS24255	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS24260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ31_RS24315	COG1595	DNA-templated transcription, initiation
DDJ31_RS24320	COG2255	four-way junction helicase activity
DDJ31_RS24325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDJ31_RS24340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DDJ31_RS24350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDJ31_RS24365	COG2072	flavoprotein involved in K transport
DDJ31_RS24430	COG1331	Highly conserved protein containing a thioredoxin domain
DDJ31_RS24465	COG1309	transcriptional regulator
DDJ31_RS24475	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DDJ31_RS24490	COG0436	Aminotransferase
DDJ31_RS24500	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DDJ31_RS24515	COG1414	Transcriptional regulator
DDJ31_RS24520	COG0251	oxidation-reduction process
DDJ31_RS24525	COG2610	gluconate transmembrane transporter activity
DDJ31_RS24570	COG2894	cell division
DDJ31_RS24605	COG2197	response regulator
DDJ31_RS24650	COG2226	methyltransferase
DDJ31_RS24655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDJ31_RS24660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DDJ31_RS24680	COG1136	(ABC) transporter
DDJ31_RS24700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDJ31_RS24720	COG0114	fumarate hydratase activity
DDJ31_RS24725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DDJ31_RS24725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DDJ31_RS24750	COG0778	Nitroreductase
DDJ31_RS24755	COG1722	exodeoxyribonuclease VII activity
DDJ31_RS24760	COG1570	exodeoxyribonuclease VII activity
DDJ31_RS24770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DDJ31_RS24785	COG0012	GTP binding
DDJ31_RS24800	COG0504	CTP synthase activity
DDJ31_RS24830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS24835	COG0778	Nitroreductase
DDJ31_RS24840	COG1733	regulation of RNA biosynthetic process
DDJ31_RS24845	COG0477	Major facilitator Superfamily
DDJ31_RS24905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DDJ31_RS24910	COG1053	succinate dehydrogenase
DDJ31_RS24940	COG4166	transmembrane transport
DDJ31_RS24945	COG0601	transmembrane transport
DDJ31_RS24950	COG0444	Belongs to the ABC transporter superfamily
DDJ31_RS24955	COG4608	Belongs to the ABC transporter superfamily
DDJ31_RS24960	COG4608	Belongs to the ABC transporter superfamily
DDJ31_RS24965	COG0444	Belongs to the ABC transporter superfamily
DDJ31_RS24970	COG0601	transmembrane transport
DDJ31_RS24975	COG0747	negative chemotaxis
DDJ31_RS24990	COG0601	transmembrane transport
DDJ31_RS24995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDJ31_RS25005	COG4608	Belongs to the ABC transporter superfamily
DDJ31_RS25020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDJ31_RS25035	COG1131	(ABC) transporter
DDJ31_RS25045	COG4585	Histidine kinase
DDJ31_RS25050	COG2197	response regulator
DDJ31_RS25085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDJ31_RS25095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DDJ31_RS25105	COG0519	Catalyzes the synthesis of GMP from XMP
DDJ31_RS25110	COG1024	Enoyl-CoA hydratase
DDJ31_RS25125	COG1595	DNA-templated transcription, initiation
DDJ31_RS25135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDJ31_RS25140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDJ31_RS25175	COG0598	Magnesium transport protein CorA
DDJ31_RS25185	COG2814	Major facilitator Superfamily
DDJ31_RS25200	COG2095	MarC family integral membrane protein
DDJ31_RS25210	COG1432	Conserved Protein
DDJ31_RS25220	COG0513	Belongs to the DEAD box helicase family
DDJ31_RS25260	COG0747	negative chemotaxis
DDJ31_RS25270	COG0601	transmembrane transport
DDJ31_RS25330	COG0210	DNA helicase
DDJ31_RS25335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDJ31_RS25340	COG2816	NAD+ diphosphatase activity
DDJ31_RS25370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DDJ31_RS25425	COG3480	Lon protease (S16) C-terminal proteolytic domain
DDJ31_RS25435	COG1615	UPF0182 protein
DDJ31_RS25465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDJ31_RS25485	COG0483	inositol monophosphate 1-phosphatase activity
DDJ31_RS25495	COG2076	Multidrug Resistance protein
DDJ31_RS25500	COG1162	GTPase activity
DDJ31_RS25505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DDJ31_RS25515	COG2135	peptidase activity
DDJ31_RS25525	COG1595	DNA-templated transcription, initiation
DDJ31_RS25530	COG5662	AntiSigma factor
DDJ31_RS25535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DDJ31_RS25535	COG2199	diguanylate cyclase activity
DDJ31_RS25550	COG0242	peptide deformylase activity
DDJ31_RS25560	COG2124	cytochrome p450
DDJ31_RS25600	COG2188	Transcriptional regulator
DDJ31_RS25605	COG2182	Extracellular solute-binding protein
DDJ31_RS25610	COG1175	transmembrane transport
DDJ31_RS25615	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS25620	COG1472	Belongs to the glycosyl hydrolase 3 family
DDJ31_RS25625	COG0363	glucosamine-6-phosphate deaminase activity
DDJ31_RS25640	COG1597	lipid kinase activity
DDJ31_RS25680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDJ31_RS25710	COG2226	methyltransferase
DDJ31_RS25730	COG4106	trans-aconitate 2-methyltransferase activity
DDJ31_RS25735	COG1126	abc transporter atp-binding protein
DDJ31_RS25750	COG0281	malic enzyme
DDJ31_RS25755	COG0604	alcohol dehydrogenase
DDJ31_RS25790	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDJ31_RS25790	COG0567	Dehydrogenase, E1 component
DDJ31_RS25795	COG2205	protein histidine kinase activity
DDJ31_RS25800	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS25820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DDJ31_RS25865	COG3883	PFAM NLP P60 protein
DDJ31_RS25865	COG0791	NLP P60 protein
DDJ31_RS25890	COG0768	penicillin binding
DDJ31_RS25930	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DDJ31_RS25950	COG0018	arginyl-trna synthetase
DDJ31_RS25955	COG0019	diaminopimelate decarboxylase activity
DDJ31_RS25960	COG0460	homoserine dehydrogenase
DDJ31_RS25965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DDJ31_RS25970	COG0083	homoserine kinase activity
DDJ31_RS25985	COG0254	rRNA binding
DDJ31_RS25990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DDJ31_RS25995	COG2890	protein-(glutamine-N5) methyltransferase activity
DDJ31_RS26005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDJ31_RS26010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DDJ31_RS26030	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDJ31_RS26035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DDJ31_RS26040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDJ31_RS26045	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DDJ31_RS26050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DDJ31_RS26055	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DDJ31_RS26060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DDJ31_RS26080	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDJ31_RS26095	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DDJ31_RS26130	COG1131	(ABC) transporter
DDJ31_RS26145	COG0346	lactoylglutathione lyase activity
DDJ31_RS26150	COG0183	Belongs to the thiolase family
DDJ31_RS26170	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS26175	COG2205	protein histidine kinase activity
DDJ31_RS26250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDJ31_RS26250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDJ31_RS26285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DDJ31_RS26290	COG0857	belongs to the CobB CobQ family
DDJ31_RS26290	COG0280	phosphate acetyltransferase
DDJ31_RS26295	COG0205	6-phosphofructokinase activity
DDJ31_RS26305	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS26310	COG1175	transmembrane transport
DDJ31_RS26320	COG4565	transcriptional regulatory protein
DDJ31_RS26325	COG3290	protein histidine kinase activity
DDJ31_RS26330	COG1301	dicarboxylic acid transport
DDJ31_RS26340	COG0477	Major facilitator Superfamily
DDJ31_RS26345	COG0789	Transcriptional regulator
DDJ31_RS26360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DDJ31_RS26375	COG0366	Alpha amylase catalytic
DDJ31_RS26385	COG0058	SHG alpha-glucan phosphorylase activity
DDJ31_RS26405	COG1132	(ABC) transporter
DDJ31_RS26410	COG1132	(ABC) transporter
DDJ31_RS26415	COG1132	(ABC) transporter
DDJ31_RS26420	COG1132	(ABC) transporter
DDJ31_RS26430	COG1376	ErfK ybiS ycfS ynhG family protein
DDJ31_RS26435	COG1376	ErfK ybiS ycfS ynhG family protein
DDJ31_RS26475	COG1119	ATPase activity
DDJ31_RS26485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDJ31_RS26490	COG3757	hydrolase, family 25
DDJ31_RS26490	COG3409	Peptidoglycan-binding domain 1 protein
DDJ31_RS26515	COG1846	Transcriptional regulator
DDJ31_RS26530	COG2409	Drug exporters of the RND superfamily
DDJ31_RS26560	COG1309	transcriptional regulator
DDJ31_RS26565	COG3693	PFAM glycoside hydrolase, family 10
DDJ31_RS26590	COG1760	l-serine dehydratase
DDJ31_RS26595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DDJ31_RS26600	COG0509	glycine decarboxylation via glycine cleavage system
DDJ31_RS26605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DDJ31_RS26625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDJ31_RS26640	COG0444	Belongs to the ABC transporter superfamily
DDJ31_RS26655	COG2860	membrane
DDJ31_RS26680	COG1309	transcriptional regulator
DDJ31_RS26705	COG0482	sulfurtransferase activity
DDJ31_RS26715	COG1611	Belongs to the LOG family
DDJ31_RS26720	COG4221	oxidoreductase activity
DDJ31_RS26730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DDJ31_RS26740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDJ31_RS26745	COG0154	amidase activity
DDJ31_RS26755	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDJ31_RS26760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDJ31_RS26780	COG2133	pyrroloquinoline quinone binding
DDJ31_RS26795	COG3300	MHYT domain
DDJ31_RS26795	COG5001	Diguanylate cyclase
DDJ31_RS26805	COG0440	acetolactate synthase activity
DDJ31_RS26810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DDJ31_RS26815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDJ31_RS26825	COG0506	proline dehydrogenase activity
DDJ31_RS26830	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS26840	COG0473	3-isopropylmalate dehydrogenase activity
DDJ31_RS26845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDJ31_RS26850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDJ31_RS26875	COG5492	domain, Protein
DDJ31_RS26880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDJ31_RS26900	COG2018	Roadblock/LC7 domain
DDJ31_RS26920	COG2018	Roadblock/LC7 domain
DDJ31_RS26925	COG5002	protein histidine kinase activity
DDJ31_RS26935	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDJ31_RS26940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDJ31_RS26975	COG1414	Transcriptional regulator
DDJ31_RS26980	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DDJ31_RS26985	COG0066	3-isopropylmalate dehydratase activity
DDJ31_RS26995	COG0776	regulation of translation
DDJ31_RS27005	COG1920	GTP binding
DDJ31_RS27015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDJ31_RS27020	COG1181	Belongs to the D-alanine--D-alanine ligase family
DDJ31_RS27040	COG0351	phosphomethylpyrimidine kinase
DDJ31_RS27045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDJ31_RS27050	COG1461	Dihydroxyacetone kinase
DDJ31_RS27060	COG0326	Molecular chaperone. Has ATPase activity
DDJ31_RS27075	COG0742	ribosomal rna small subunit methyltransferase
DDJ31_RS27080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DDJ31_RS27095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DDJ31_RS27100	COG0571	ribonuclease III activity
DDJ31_RS27105	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDJ31_RS27110	COG1733	regulation of RNA biosynthetic process
DDJ31_RS27115	COG2340	Cysteine-rich secretory protein family
DDJ31_RS27120	COG1254	Belongs to the acylphosphatase family
DDJ31_RS27130	COG1196	nuclear chromosome segregation
DDJ31_RS27135	COG0477	Major facilitator Superfamily
DDJ31_RS27170	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DDJ31_RS27180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDJ31_RS27190	COG0442	prolyl-tRNA aminoacylation
DDJ31_RS27200	COG0228	four-way junction DNA binding
DDJ31_RS27205	COG1837	Belongs to the UPF0109 family
DDJ31_RS27210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DDJ31_RS27215	COG0336	Belongs to the RNA methyltransferase TrmD family
DDJ31_RS27220	COG0335	large ribosomal subunit rRNA binding
DDJ31_RS27225	COG0681	Belongs to the peptidase S26 family
DDJ31_RS27235	COG0681	Belongs to the peptidase S26 family
DDJ31_RS27255	COG0792	nuclease activity
DDJ31_RS27270	COG1191	sigma factor activity
DDJ31_RS27285	COG0052	Belongs to the universal ribosomal protein uS2 family
DDJ31_RS27290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DDJ31_RS27295	COG0528	UMP kinase activity
DDJ31_RS27300	COG0233	cytoplasmic translational termination
DDJ31_RS27305	COG0575	Belongs to the CDS family
DDJ31_RS27310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DDJ31_RS27320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DDJ31_RS27325	COG3842	ATPase activity
DDJ31_RS27355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDJ31_RS27365	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS27375	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS27380	COG1309	transcriptional regulator
DDJ31_RS27390	COG0477	Major facilitator Superfamily
DDJ31_RS27390	COG2814	Major facilitator Superfamily
DDJ31_RS27400	COG2159	amidohydrolase
DDJ31_RS27405	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS27410	COG5002	protein histidine kinase activity
DDJ31_RS27410	COG5000	phosphorelay sensor kinase activity
DDJ31_RS27445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDJ31_RS27470	COG3842	ATPase activity
DDJ31_RS27475	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDJ31_RS27480	COG1177	transmembrane transport
DDJ31_RS27485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDJ31_RS27525	COG1472	Belongs to the glycosyl hydrolase 3 family
DDJ31_RS27530	COG1653	transport
DDJ31_RS27535	COG4209	transmembrane transport
DDJ31_RS27540	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS27580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DDJ31_RS27585	COG0750	zinc metalloprotease
DDJ31_RS27590	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DDJ31_RS27605	COG0442	prolyl-tRNA aminoacylation
DDJ31_RS27625	COG0779	Required for maturation of 30S ribosomal subunits
DDJ31_RS27640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DDJ31_RS27650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DDJ31_RS27655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DDJ31_RS27670	COG0455	bacterial-type flagellum organization
DDJ31_RS27680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DDJ31_RS27685	COG1185	polyribonucleotide nucleotidyltransferase activity
DDJ31_RS27690	COG0612	Peptidase, M16
DDJ31_RS27695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DDJ31_RS27715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDJ31_RS27720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DDJ31_RS27750	COG2770	Histidine kinase
DDJ31_RS27750	COG2208	phosphoserine phosphatase activity
DDJ31_RS27755	COG3850	Histidine kinase
DDJ31_RS27755	COG3437	response regulator, receiver
DDJ31_RS27755	COG4999	Histidine kinase
DDJ31_RS27755	COG2205	protein histidine kinase activity
DDJ31_RS27765	COG1674	ftsk spoiiie
DDJ31_RS27775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDJ31_RS27785	COG1058	Belongs to the CinA family
DDJ31_RS27785	COG1546	Belongs to the CinA family
DDJ31_RS27790	COG1396	sequence-specific DNA binding
DDJ31_RS27795	COG0783	Belongs to the Dps family
DDJ31_RS27800	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS27805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDJ31_RS27810	COG1201	RNA secondary structure unwinding
DDJ31_RS27815	COG2207	Transcriptional regulator
DDJ31_RS27815	COG1917	Cupin 2, conserved barrel domain protein
DDJ31_RS27840	COG0628	permease
DDJ31_RS27845	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DDJ31_RS27870	COG0765	amino acid transport
DDJ31_RS27875	COG0765	amino acid transport
DDJ31_RS27880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDJ31_RS27885	COG1126	abc transporter atp-binding protein
DDJ31_RS27890	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS27895	COG2205	protein histidine kinase activity
DDJ31_RS27900	COG2358	TRAP transporter, solute receptor (TAXI family
DDJ31_RS27925	COG2197	response regulator
DDJ31_RS27935	COG2843	Capsule synthesis protein
DDJ31_RS27960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDJ31_RS27980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DDJ31_RS27990	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DDJ31_RS27995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDJ31_RS28005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDJ31_RS28035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DDJ31_RS28040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DDJ31_RS28045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDJ31_RS28060	COG0588	phosphoglycerate mutase activity
DDJ31_RS28065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DDJ31_RS28105	COG2186	Transcriptional regulator
DDJ31_RS28130	COG0187	DNA topoisomerase II activity
DDJ31_RS28140	COG4585	Histidine kinase
DDJ31_RS28145	COG2197	response regulator
DDJ31_RS28155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDJ31_RS28160	COG4565	transcriptional regulatory protein
DDJ31_RS28170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDJ31_RS28180	COG4565	transcriptional regulatory protein
DDJ31_RS28185	COG3290	protein histidine kinase activity
DDJ31_RS28220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDJ31_RS28225	COG0612	Peptidase, M16
DDJ31_RS28240	COG1802	Transcriptional regulator
DDJ31_RS28245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ31_RS28250	COG0045	succinate-CoA ligase (ADP-forming) activity
DDJ31_RS28250	COG1042	CoA-binding domain protein
DDJ31_RS28250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDJ31_RS28265	COG1435	thymidine kinase activity
DDJ31_RS28315	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS28320	COG2205	protein histidine kinase activity
DDJ31_RS28345	COG0756	dUTP diphosphatase activity
DDJ31_RS28385	COG0569	domain protein
DDJ31_RS28390	COG0531	amino acid
DDJ31_RS28395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDJ31_RS28420	COG0667	Aldo Keto reductase
DDJ31_RS28435	COG0583	DNA-binding transcription factor activity
DDJ31_RS28460	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS28500	COG0667	Aldo Keto reductase
DDJ31_RS28505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DDJ31_RS28535	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DDJ31_RS28560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DDJ31_RS28565	COG4591	ABC-type transport system involved in lipoprotein release permease component
DDJ31_RS28565	COG1136	(ABC) transporter
DDJ31_RS28575	COG4585	Histidine kinase
DDJ31_RS28580	COG2197	response regulator
DDJ31_RS28625	COG2268	Band 7 protein
DDJ31_RS28670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDJ31_RS28670	COG2080	2 iron, 2 sulfur cluster binding
DDJ31_RS28720	COG1799	cell septum assembly
DDJ31_RS28750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DDJ31_RS28770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDJ31_RS28780	COG1024	Enoyl-CoA hydratase
DDJ31_RS28800	COG0529	Catalyzes the synthesis of activated sulfate
DDJ31_RS28840	COG3629	intracellular signal transduction
DDJ31_RS28855	COG3903	Transcriptional regulator
DDJ31_RS28855	COG3629	intracellular signal transduction
DDJ31_RS28865	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DDJ31_RS28880	COG2313	pseudouridylate synthase activity
DDJ31_RS28885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS28885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS28890	COG2807	transmembrane transport
DDJ31_RS28895	COG2186	Transcriptional regulator
DDJ31_RS28925	COG0640	Transcriptional regulator
DDJ31_RS28935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDJ31_RS28970	COG1733	regulation of RNA biosynthetic process
DDJ31_RS29055	COG0017	Asparaginyl-tRNA synthetase
DDJ31_RS29105	COG1061	Type III restriction enzyme res subunit
DDJ31_RS29110	COG1104	cysteine desulfurase activity
DDJ31_RS29125	COG0519	Catalyzes the synthesis of GMP from XMP
DDJ31_RS29325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDJ31_RS29345	COG2771	luxR family
DDJ31_RS29365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DDJ31_RS29380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDJ31_RS29390	COG1051	belongs to the nudix hydrolase family
DDJ31_RS29405	COG2192	nodulation
DDJ31_RS29435	COG0494	nUDIX hydrolase
DDJ31_RS29450	COG0181	hydroxymethylbilane synthase activity
DDJ31_RS29475	COG1051	belongs to the nudix hydrolase family
DDJ31_RS29485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDJ31_RS29520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDJ31_RS29530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DDJ31_RS29540	COG3537	Alpha-1,2-mannosidase
DDJ31_RS29545	COG3458	cephalosporin-C deacetylase activity
DDJ31_RS29550	COG4209	transmembrane transport
DDJ31_RS29555	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS29590	COG1653	transport
DDJ31_RS29595	COG1175	transmembrane transport
DDJ31_RS29600	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS29605	COG1940	carbohydrate kinase activity
DDJ31_RS29610	COG4213	ABC transporter substrate-binding protein
DDJ31_RS29620	COG4214	carbohydrate transport
DDJ31_RS29625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDJ31_RS29630	COG0531	amino acid
DDJ31_RS29660	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDJ31_RS29660	COG1024	Enoyl-CoA hydratase
DDJ31_RS29665	COG0183	Belongs to the thiolase family
DDJ31_RS29670	COG1609	Transcriptional regulator
DDJ31_RS29675	COG3250	beta-galactosidase activity
DDJ31_RS29685	COG1175	transmembrane transport
DDJ31_RS29695	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DDJ31_RS29710	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DDJ31_RS29725	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDJ31_RS29765	COG3220	belongs to the UPF0276 family
DDJ31_RS29780	COG2326	polyphosphate kinase activity
DDJ31_RS29790	COG0330	HflC and HflK could
DDJ31_RS29820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DDJ31_RS29825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDJ31_RS29835	COG2205	protein histidine kinase activity
DDJ31_RS29840	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS29845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDJ31_RS29860	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DDJ31_RS29870	COG1174	glycine betaine transport
DDJ31_RS29875	COG1174	glycine betaine transport
DDJ31_RS29890	COG2018	Roadblock/LC7 domain
DDJ31_RS29895	COG5002	protein histidine kinase activity
DDJ31_RS29905	COG2986	histidine ammonia-lyase
DDJ31_RS29950	COG0640	Transcriptional regulator
DDJ31_RS29955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDJ31_RS29960	COG1316	TRANSCRIPTIONal
DDJ31_RS30020	COG3173	Aminoglycoside phosphotransferase
DDJ31_RS30085	COG2409	Drug exporters of the RND superfamily
DDJ31_RS30095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DDJ31_RS30110	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DDJ31_RS30135	COG0529	Catalyzes the synthesis of activated sulfate
DDJ31_RS30140	COG0175	sulfate reduction
DDJ31_RS30170	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS30235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDJ31_RS30240	COG2272	Belongs to the type-B carboxylesterase lipase family
DDJ31_RS30245	COG2040	homocysteine
DDJ31_RS30325	COG0277	FAD linked oxidase domain protein
DDJ31_RS30345	COG1162	GTPase activity
DDJ31_RS30355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDJ31_RS30370	COG0028	Belongs to the TPP enzyme family
DDJ31_RS30400	COG1802	Transcriptional regulator
DDJ31_RS30425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDJ31_RS30430	COG2252	PERMEase
DDJ31_RS30440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDJ31_RS30440	COG0515	serine threonine protein kinase
DDJ31_RS30465	COG2197	response regulator
DDJ31_RS30475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DDJ31_RS30490	COG0604	alcohol dehydrogenase
DDJ31_RS30520	COG1309	transcriptional regulator
DDJ31_RS30535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DDJ31_RS30540	COG0022	dehydrogenase e1 component
DDJ31_RS30560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDJ31_RS30565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDJ31_RS30580	COG2197	response regulator
DDJ31_RS30585	COG2867	negative regulation of translational initiation
DDJ31_RS30590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDJ31_RS30595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDJ31_RS30600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDJ31_RS30605	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS30610	COG0477	Major facilitator Superfamily
DDJ31_RS30615	COG2130	NADP-dependent
DDJ31_RS30645	COG0596	Alpha beta hydrolase
DDJ31_RS30655	COG0596	Alpha beta hydrolase
DDJ31_RS30665	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DDJ31_RS30685	COG0477	Major facilitator Superfamily
DDJ31_RS30690	COG2378	regulation of single-species biofilm formation
DDJ31_RS30715	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS30740	COG1819	glycosyl
DDJ31_RS30745	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS30785	COG2318	DinB family
DDJ31_RS30805	COG1120	ATPase activity
DDJ31_RS30825	COG3507	Belongs to the glycosyl hydrolase 43 family
DDJ31_RS30825	COG2382	esterase
DDJ31_RS30825	COG3693	PFAM glycoside hydrolase, family 10
DDJ31_RS30830	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DDJ31_RS30865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DDJ31_RS30895	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS30905	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DDJ31_RS30905	COG2508	Transcriptional regulator
DDJ31_RS30950	COG3409	Peptidoglycan-binding domain 1 protein
DDJ31_RS30970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDJ31_RS30975	COG0156	8-amino-7-oxononanoate synthase activity
DDJ31_RS30990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDJ31_RS30995	COG3962	Belongs to the TPP enzyme family
DDJ31_RS31000	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS31050	COG0583	DNA-binding transcription factor activity
DDJ31_RS31060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDJ31_RS31075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDJ31_RS31080	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS31090	COG3321	synthase
DDJ31_RS31090	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS31090	COG0604	alcohol dehydrogenase
DDJ31_RS31100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDJ31_RS31120	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS31130	COG0019	diaminopimelate decarboxylase activity
DDJ31_RS31135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDJ31_RS31140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDJ31_RS31155	COG0300	oxidoreductase activity
DDJ31_RS31180	COG2197	response regulator
DDJ31_RS31185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDJ31_RS31270	COG0577	efflux transmembrane transporter activity
DDJ31_RS31270	COG1136	(ABC) transporter
DDJ31_RS31275	COG3409	Peptidoglycan-binding domain 1 protein
DDJ31_RS31320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDJ31_RS31360	COG2197	response regulator
DDJ31_RS31365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDJ31_RS31370	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS31380	COG3960	tartronate-semialdehyde synthase activity
DDJ31_RS31385	COG2084	Dehydrogenase
DDJ31_RS31390	COG3622	Belongs to the hyi family
DDJ31_RS31410	COG2351	hydroxyisourate hydrolase activity
DDJ31_RS31425	COG2233	PERMEase
DDJ31_RS31445	COG0406	alpha-ribazole phosphatase activity
DDJ31_RS31450	COG0436	Aminotransferase
DDJ31_RS31455	COG1733	regulation of RNA biosynthetic process
DDJ31_RS31470	COG4264	IucA IucC family
DDJ31_RS31515	COG1414	Transcriptional regulator
DDJ31_RS31520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDJ31_RS31525	COG4266	Belongs to the allantoicase family
DDJ31_RS31555	COG0673	inositol 2-dehydrogenase activity
DDJ31_RS31575	COG2197	response regulator
DDJ31_RS31585	COG0673	inositol 2-dehydrogenase activity
DDJ31_RS31590	COG2188	Transcriptional regulator
DDJ31_RS31600	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDJ31_RS31610	COG1940	carbohydrate kinase activity
DDJ31_RS31620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDJ31_RS31660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS31670	COG1063	alcohol dehydrogenase
DDJ31_RS31675	COG2205	protein histidine kinase activity
DDJ31_RS31680	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS31715	COG0516	GMP reductase activity
DDJ31_RS31715	COG0517	IMP dehydrogenase activity
DDJ31_RS31725	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DDJ31_RS31740	COG2326	polyphosphate kinase activity
DDJ31_RS31755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DDJ31_RS31760	COG0596	Alpha beta hydrolase
DDJ31_RS31770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDJ31_RS31775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DDJ31_RS31795	COG1126	abc transporter atp-binding protein
DDJ31_RS31800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDJ31_RS31805	COG0765	amino acid transport
DDJ31_RS31810	COG0765	amino acid transport
DDJ31_RS31825	COG0405	Gamma-glutamyltransferase
DDJ31_RS31845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDJ31_RS31860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDJ31_RS31870	COG1953	Uracil, thiamine, allantoin
DDJ31_RS31885	COG0483	inositol monophosphate 1-phosphatase activity
DDJ31_RS31895	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DDJ31_RS31900	COG1609	Transcriptional regulator
DDJ31_RS31915	COG1309	transcriptional regulator
DDJ31_RS31920	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS31955	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DDJ31_RS31965	COG1929	Belongs to the glycerate kinase type-1 family
DDJ31_RS31975	COG0688	phosphatidylethanolamine metabolic process
DDJ31_RS31980	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS31995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDJ31_RS31995	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDJ31_RS32010	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDJ31_RS32055	COG2226	methyltransferase
DDJ31_RS32075	COG2362	D-Aminopeptidase
DDJ31_RS32080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDJ31_RS32090	COG1619	proteins homologs of microcin C7 resistance protein MccF
DDJ31_RS32125	COG2226	methyltransferase
DDJ31_RS32135	COG0406	alpha-ribazole phosphatase activity
DDJ31_RS32140	COG0488	(ABC) transporter
DDJ31_RS32150	COG0693	protein deglycase activity
DDJ31_RS32205	COG0443	Heat shock 70 kDa protein
DDJ31_RS32230	COG2154	pterin-4-alpha-carbinolamine dehydratase
DDJ31_RS32240	COG3401	FG-GAP repeat protein
DDJ31_RS32250	COG4733	cellulase activity
DDJ31_RS32250	COG5297	Belongs to the glycosyl hydrolase family 6
DDJ31_RS32260	COG5297	Belongs to the glycosyl hydrolase family 6
DDJ31_RS32275	COG0656	L-ascorbic acid biosynthetic process
DDJ31_RS32295	COG0583	DNA-binding transcription factor activity
DDJ31_RS32305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DDJ31_RS32310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DDJ31_RS32320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDJ31_RS32330	COG1940	carbohydrate kinase activity
DDJ31_RS32335	COG1129	ABC transporter
DDJ31_RS32340	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDJ31_RS32350	COG0673	inositol 2-dehydrogenase activity
DDJ31_RS32425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDJ31_RS32435	COG0045	succinate-CoA ligase (ADP-forming) activity
DDJ31_RS32445	COG1012	belongs to the aldehyde dehydrogenase family
DDJ31_RS32490	COG1473	amidohydrolase
DDJ31_RS32500	COG2226	methyltransferase
DDJ31_RS32515	COG1733	regulation of RNA biosynthetic process
DDJ31_RS32565	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS32580	COG1228	amidohydrolase
DDJ31_RS32600	COG0076	glutamate decarboxylase activity
DDJ31_RS32620	COG0640	Transcriptional regulator
DDJ31_RS32625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDJ31_RS32635	COG1253	flavin adenine dinucleotide binding
DDJ31_RS32645	COG3594	Acyltransferase
DDJ31_RS32670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDJ31_RS32675	COG2182	Extracellular solute-binding protein
DDJ31_RS32680	COG1175	transmembrane transport
DDJ31_RS32685	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS32690	COG2723	6-phospho-beta-galactosidase activity
DDJ31_RS32705	COG0747	negative chemotaxis
DDJ31_RS32710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDJ31_RS32735	COG0297	glycogen (starch) synthase activity
DDJ31_RS32750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDJ31_RS32765	COG3467	pyridoxamine 5'-phosphate
DDJ31_RS32775	COG0477	Major facilitator Superfamily
DDJ31_RS32785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDJ31_RS32795	COG0406	alpha-ribazole phosphatase activity
DDJ31_RS32800	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DDJ31_RS32805	COG0166	Belongs to the GPI family
DDJ31_RS32845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DDJ31_RS32865	COG3250	beta-galactosidase activity
DDJ31_RS32875	COG1175	transmembrane transport
DDJ31_RS32885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDJ31_RS32895	COG1486	melibiose metabolic process
DDJ31_RS32905	COG3469	chitinase activity
DDJ31_RS32955	COG1175	transmembrane transport
DDJ31_RS32960	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS32965	COG0366	Alpha amylase catalytic
DDJ31_RS32985	COG0438	transferase activity, transferring glycosyl groups
DDJ31_RS32995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDJ31_RS33000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DDJ31_RS33040	COG2255	four-way junction helicase activity
DDJ31_RS33055	COG3511	phospholipase C
DDJ31_RS33085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DDJ31_RS33090	COG0477	Major facilitator Superfamily
DDJ31_RS33100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDJ31_RS33105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDJ31_RS33110	COG3485	protocatechuate 3,4-dioxygenase
DDJ31_RS33115	COG3485	protocatechuate 3,4-dioxygenase
DDJ31_RS33130	COG1846	Transcriptional regulator
DDJ31_RS33140	COG1793	dna ligase
DDJ31_RS33185	COG1834	amidinotransferase
DDJ31_RS33190	COG0488	(ABC) transporter
DDJ31_RS33210	COG1515	deoxyribonuclease V activity
DDJ31_RS33220	COG3268	Saccharopine dehydrogenase
DDJ31_RS33225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDJ31_RS33230	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS33235	COG0183	Belongs to the thiolase family
DDJ31_RS33240	COG1024	Enoyl-CoA hydratase
DDJ31_RS33240	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDJ31_RS33250	COG1113	amino acid transport
DDJ31_RS33260	COG2936	dipeptidyl-peptidase activity
DDJ31_RS33270	COG0488	(ABC) transporter
DDJ31_RS33275	COG2183	response to ionizing radiation
DDJ31_RS33285	COG4977	sequence-specific DNA binding
DDJ31_RS33295	COG1024	Enoyl-CoA hydratase
DDJ31_RS33305	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DDJ31_RS33345	COG1134	teichoic acid transport
DDJ31_RS33350	COG1562	ergosterol biosynthetic process
DDJ31_RS33365	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DDJ31_RS33375	COG1657	PFAM Prenyltransferase squalene oxidase
DDJ31_RS33390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DDJ31_RS33395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDJ31_RS33425	COG2755	lipolytic protein G-D-S-L family
DDJ31_RS33435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDJ31_RS33475	COG0477	Major facilitator Superfamily
DDJ31_RS33485	COG0583	DNA-binding transcription factor activity
DDJ31_RS33490	COG1063	alcohol dehydrogenase
DDJ31_RS33500	COG0583	DNA-binding transcription factor activity
DDJ31_RS33525	COG3958	Transketolase
DDJ31_RS33565	COG4221	oxidoreductase activity
DDJ31_RS33585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ31_RS33600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDJ31_RS33630	COG1309	transcriptional regulator
DDJ31_RS33635	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DDJ31_RS33675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DDJ31_RS33735	COG2770	Histidine kinase
DDJ31_RS33735	COG2208	phosphoserine phosphatase activity
DDJ31_RS33740	COG0596	Alpha beta hydrolase
DDJ31_RS33750	COG3226	Transcriptional regulator
DDJ31_RS33755	COG0596	Alpha beta hydrolase
DDJ31_RS33755	COG2945	thiolester hydrolase activity
DDJ31_RS33775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DDJ31_RS33790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDJ31_RS33810	COG1940	carbohydrate kinase activity
DDJ31_RS33815	COG2188	Transcriptional regulator
DDJ31_RS33820	COG3962	Belongs to the TPP enzyme family
DDJ31_RS33845	COG0673	inositol 2-dehydrogenase activity
DDJ31_RS33850	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS33860	COG1609	Transcriptional regulator
DDJ31_RS33875	COG1609	Transcriptional regulator
DDJ31_RS33890	COG3485	protocatechuate 3,4-dioxygenase
DDJ31_RS33895	COG1454	alcohol dehydrogenase
DDJ31_RS33900	COG2186	Transcriptional regulator
DDJ31_RS33905	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDJ31_RS33910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DDJ31_RS33925	COG2814	Major facilitator Superfamily
DDJ31_RS33935	COG0477	Major facilitator Superfamily
DDJ31_RS33945	COG3385	transposase activity
DDJ31_RS33970	COG0330	HflC and HflK could
DDJ31_RS33985	COG1609	Transcriptional regulator
DDJ31_RS33995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDJ31_RS34005	COG1595	DNA-templated transcription, initiation
DDJ31_RS34055	COG2124	cytochrome p450
DDJ31_RS34060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDJ31_RS34085	COG0477	Major facilitator Superfamily
DDJ31_RS34090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDJ31_RS34095	COG0435	Glutathione S-transferase
DDJ31_RS34115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS34120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS34130	COG2197	response regulator
DDJ31_RS34140	COG1404	Belongs to the peptidase S8 family
DDJ31_RS34155	COG2124	cytochrome p450
DDJ31_RS34165	COG2838	Isocitrate dehydrogenase
DDJ31_RS34170	COG0668	transmembrane transport
DDJ31_RS34180	COG1132	(ABC) transporter
DDJ31_RS34215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DDJ31_RS34220	COG1652	LysM domain
DDJ31_RS34235	COG0297	glycogen (starch) synthase activity
DDJ31_RS34240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DDJ31_RS34245	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDJ31_RS34250	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDJ31_RS34255	COG1129	ABC transporter
DDJ31_RS34260	COG1879	ABC-type sugar transport system periplasmic component
DDJ31_RS34265	COG1609	Transcriptional regulator
DDJ31_RS34280	COG3537	Alpha-1,2-mannosidase
DDJ31_RS34325	COG1609	Transcriptional regulator
DDJ31_RS34335	COG1175	transmembrane transport
DDJ31_RS34340	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS34380	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDJ31_RS34410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDJ31_RS34410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DDJ31_RS34415	COG0726	polysaccharide deacetylase
DDJ31_RS34460	COG0583	DNA-binding transcription factor activity
DDJ31_RS34470	COG1053	succinate dehydrogenase
DDJ31_RS34475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DDJ31_RS34495	COG0542	response to heat
DDJ31_RS34500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS34505	COG0523	cobalamin synthesis protein
DDJ31_RS34525	COG3360	Dodecin
DDJ31_RS34530	COG2182	Extracellular solute-binding protein
DDJ31_RS34535	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DDJ31_RS34540	COG0121	glutamine amidotransferase
DDJ31_RS34545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DDJ31_RS34550	COG3572	ergothioneine biosynthetic process
DDJ31_RS34560	COG2268	Band 7 protein
DDJ31_RS34590	COG3001	Fructosamine kinase
DDJ31_RS34610	COG2211	Major facilitator Superfamily
DDJ31_RS34625	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS34630	COG0235	Class ii aldolase
DDJ31_RS34635	COG3395	kinase activity
DDJ31_RS34650	COG1349	DNA-binding transcription factor activity
DDJ31_RS34655	COG0656	L-ascorbic acid biosynthetic process
DDJ31_RS34660	COG2814	Major facilitator Superfamily
DDJ31_RS34715	COG1609	Transcriptional regulator
DDJ31_RS34720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDJ31_RS34730	COG0242	peptide deformylase activity
DDJ31_RS34755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDJ31_RS34760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS34765	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS34770	COG0183	Belongs to the thiolase family
DDJ31_RS34775	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDJ31_RS34775	COG1024	Enoyl-CoA hydratase
DDJ31_RS34785	COG1960	acyl-CoA dehydrogenase activity
DDJ31_RS34790	COG1309	transcriptional regulator
DDJ31_RS34810	COG1309	transcriptional regulator
DDJ31_RS34835	COG0789	Transcriptional regulator
DDJ31_RS34885	COG4221	oxidoreductase activity
DDJ31_RS34905	COG0672	)-iron permease
DDJ31_RS34910	COG0586	Pfam SNARE associated Golgi protein
DDJ31_RS34950	COG2755	lipolytic protein G-D-S-L family
DDJ31_RS34955	COG1132	(ABC) transporter
DDJ31_RS34960	COG1819	glycosyl
DDJ31_RS35000	COG0501	Belongs to the peptidase M48B family
DDJ31_RS35025	COG4941	Belongs to the sigma-70 factor family
DDJ31_RS35030	COG3795	YCII-related domain
DDJ31_RS35040	COG3903	Transcriptional regulator
DDJ31_RS35040	COG3629	intracellular signal transduction
DDJ31_RS35045	COG0477	Major facilitator Superfamily
DDJ31_RS35050	COG1309	transcriptional regulator
DDJ31_RS35060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDJ31_RS35065	COG0475	glutathione-regulated potassium exporter activity
DDJ31_RS35115	COG0022	dehydrogenase e1 component
DDJ31_RS35120	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDJ31_RS35130	COG0309	Hydrogenase expression formation protein (HypE)
DDJ31_RS35135	COG0409	Hydrogenase expression formation protein
DDJ31_RS35140	COG0298	carbon dioxide binding
DDJ31_RS35145	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DDJ31_RS35170	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DDJ31_RS35185	COG0375	protein maturation
DDJ31_RS35210	COG1309	transcriptional regulator
DDJ31_RS35260	COG1316	TRANSCRIPTIONal
DDJ31_RS35285	COG0667	Aldo Keto reductase
DDJ31_RS35305	COG2964	Protein conserved in bacteria
DDJ31_RS35325	COG0542	response to heat
DDJ31_RS35335	COG1174	glycine betaine transport
DDJ31_RS35340	COG1174	glycine betaine transport
DDJ31_RS35345	COG1732	Glycine betaine
DDJ31_RS35355	COG1556	Lactate utilization protein
DDJ31_RS35360	COG1139	Iron-sulfur cluster binding protein
DDJ31_RS35365	COG0247	lactate metabolic process
DDJ31_RS35370	COG1070	Carbohydrate kinase
DDJ31_RS35375	COG3347	Dehydrogenase
DDJ31_RS35375	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS35380	COG4952	isomerase
DDJ31_RS35390	COG3896	Chloramphenicol phosphotransferase-like protein
DDJ31_RS35400	COG1309	transcriptional regulator
DDJ31_RS35415	COG4952	isomerase
DDJ31_RS35420	COG1129	ABC transporter
DDJ31_RS35430	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDJ31_RS35435	COG1879	ABC-type sugar transport system periplasmic component
DDJ31_RS35450	COG1609	Transcriptional regulator
DDJ31_RS35460	COG1357	PFAM Pentapeptide repeats (8 copies)
DDJ31_RS35465	COG2124	cytochrome p450
DDJ31_RS35465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DDJ31_RS35470	COG1309	transcriptional regulator
DDJ31_RS35480	COG2706	6-phosphogluconolactonase activity
DDJ31_RS35540	COG1796	DNA polymerase
DDJ31_RS35540	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDJ31_RS35565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DDJ31_RS35585	COG1891	lyase activity
DDJ31_RS35610	COG4977	sequence-specific DNA binding
DDJ31_RS35645	COG2124	cytochrome p450
DDJ31_RS35650	COG2124	cytochrome p450
DDJ31_RS35670	COG2124	cytochrome p450
DDJ31_RS35685	COG1486	melibiose metabolic process
DDJ31_RS35695	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS35715	COG0667	Aldo Keto reductase
DDJ31_RS35740	COG1595	DNA-templated transcription, initiation
DDJ31_RS35750	COG3250	beta-galactosidase activity
DDJ31_RS35760	COG1846	Transcriptional regulator
DDJ31_RS35770	COG2267	carboxylic ester hydrolase activity
DDJ31_RS35795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDJ31_RS35835	COG2197	response regulator
DDJ31_RS35840	COG1132	(ABC) transporter
DDJ31_RS35845	COG1132	(ABC) transporter
DDJ31_RS35855	COG0515	serine threonine protein kinase
DDJ31_RS35895	COG0477	Major facilitator Superfamily
DDJ31_RS35930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DDJ31_RS35955	COG1132	(ABC) transporter
DDJ31_RS36020	COG1175	transmembrane transport
DDJ31_RS36025	COG1940	carbohydrate kinase activity
DDJ31_RS36025	COG1846	Transcriptional regulator
DDJ31_RS36060	COG1309	transcriptional regulator
DDJ31_RS36095	COG2971	BadF BadG BcrA BcrD
DDJ31_RS36100	COG1940	carbohydrate kinase activity
DDJ31_RS36105	COG1653	transport
DDJ31_RS36110	COG1175	transmembrane transport
DDJ31_RS36115	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS36125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDJ31_RS36140	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DDJ31_RS36225	COG2409	Drug exporters of the RND superfamily
DDJ31_RS36255	COG2508	Transcriptional regulator
DDJ31_RS36265	COG0411	ABC transporter
DDJ31_RS36285	COG0667	Aldo Keto reductase
DDJ31_RS36290	COG1132	(ABC) transporter
DDJ31_RS36300	COG4977	sequence-specific DNA binding
DDJ31_RS36350	COG3290	protein histidine kinase activity
DDJ31_RS36380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DDJ31_RS36385	COG0640	Transcriptional regulator
DDJ31_RS36390	COG2217	Heavy metal translocating P-type atpase
DDJ31_RS36405	COG1024	Enoyl-CoA hydratase
DDJ31_RS36420	COG3800	Transcriptional regulator
DDJ31_RS36420	COG1396	sequence-specific DNA binding
DDJ31_RS36430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DDJ31_RS36450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DDJ31_RS36495	COG0277	FAD linked oxidase domain protein
DDJ31_RS36500	COG1597	lipid kinase activity
DDJ31_RS36545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS36550	COG3842	ATPase activity
DDJ31_RS36560	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDJ31_RS36570	COG2188	Transcriptional regulator
DDJ31_RS36575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DDJ31_RS36580	COG3537	Alpha-1,2-mannosidase
DDJ31_RS36600	COG0714	Associated with various cellular activities
DDJ31_RS36605	COG3864	Putative metallopeptidase domain
DDJ31_RS36620	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS36640	COG0745	RESPONSE REGULATOR receiver
DDJ31_RS36680	COG0656	L-ascorbic acid biosynthetic process
DDJ31_RS36715	COG0009	L-threonylcarbamoyladenylate synthase
DDJ31_RS36770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DDJ31_RS36785	COG2197	response regulator
DDJ31_RS36790	COG3851	Histidine kinase
DDJ31_RS36820	COG0667	Aldo Keto reductase
DDJ31_RS36865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDJ31_RS36870	COG1733	regulation of RNA biosynthetic process
DDJ31_RS36905	COG2124	cytochrome p450
DDJ31_RS36910	COG2124	cytochrome p450
DDJ31_RS36915	COG4213	ABC transporter substrate-binding protein
DDJ31_RS36970	COG3903	Transcriptional regulator
DDJ31_RS36970	COG3629	intracellular signal transduction
DDJ31_RS36980	COG0148	phosphopyruvate hydratase activity
DDJ31_RS37005	COG1191	sigma factor activity
DDJ31_RS37015	COG4251	negative regulation of phosphorylation
DDJ31_RS37020	COG0784	Response regulator, receiver
DDJ31_RS37030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS37035	COG3153	acetyltransferase
DDJ31_RS37045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DDJ31_RS37050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDJ31_RS37055	COG3842	ATPase activity
DDJ31_RS37065	COG1177	transmembrane transport
DDJ31_RS37070	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDJ31_RS37075	COG1522	sequence-specific DNA binding
DDJ31_RS37160	COG0714	Associated with various cellular activities
DDJ31_RS37180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DDJ31_RS37235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDJ31_RS37245	COG0367	asparagine synthase
DDJ31_RS37250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDJ31_RS37275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS37280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDJ31_RS37285	COG4521	taurine ABC transporter
DDJ31_RS37290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DDJ31_RS37295	COG2175	clavaminate synthase activity
DDJ31_RS37315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS37330	COG0477	Major facilitator Superfamily
DDJ31_RS37365	COG1278	Cold shock
DDJ31_RS37375	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS37380	COG0477	Major facilitator Superfamily
DDJ31_RS37425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDJ31_RS37445	COG1126	abc transporter atp-binding protein
DDJ31_RS37450	COG0765	amino acid transport
DDJ31_RS37485	COG3250	beta-galactosidase activity
DDJ31_RS37495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DDJ31_RS37500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDJ31_RS37550	COG2072	flavoprotein involved in K transport
DDJ31_RS37570	COG1940	carbohydrate kinase activity
DDJ31_RS37585	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS37590	COG4209	transmembrane transport
DDJ31_RS37600	COG2318	DinB family
DDJ31_RS37610	COG0277	FAD linked oxidase domain protein
DDJ31_RS37635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS37640	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS37645	COG1175	transmembrane transport
DDJ31_RS37655	COG0366	Alpha amylase catalytic
DDJ31_RS37660	COG1653	transport
DDJ31_RS37665	COG1695	Transcriptional regulator
DDJ31_RS37670	COG0577	efflux transmembrane transporter activity
DDJ31_RS37670	COG1136	(ABC) transporter
DDJ31_RS37690	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDJ31_RS37695	COG1129	ABC transporter
DDJ31_RS37725	COG0701	Predicted permease
DDJ31_RS37745	COG2205	protein histidine kinase activity
DDJ31_RS37750	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS37765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDJ31_RS37770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDJ31_RS37820	COG0431	NADPH-dependent FMN reductase
DDJ31_RS37835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDJ31_RS37855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDJ31_RS37890	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DDJ31_RS37895	COG0477	Major facilitator Superfamily
DDJ31_RS37915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DDJ31_RS37915	COG4106	trans-aconitate 2-methyltransferase activity
DDJ31_RS37930	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DDJ31_RS37975	COG0747	negative chemotaxis
DDJ31_RS37980	COG0601	transmembrane transport
DDJ31_RS38000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDJ31_RS38000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DDJ31_RS38000	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DDJ31_RS38000	COG3321	synthase
DDJ31_RS38010	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ31_RS38020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDJ31_RS38060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS38080	COG1045	serine acetyltransferase
DDJ31_RS38140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDJ31_RS38150	COG0583	DNA-binding transcription factor activity
DDJ31_RS38160	COG2855	membrane
DDJ31_RS38195	COG3831	ATPase activity
DDJ31_RS38210	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ31_RS38220	COG2197	response regulator
DDJ31_RS38235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDJ31_RS38240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS38250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDJ31_RS38270	COG0667	Aldo Keto reductase
DDJ31_RS38280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDJ31_RS38295	COG3507	Belongs to the glycosyl hydrolase 43 family
DDJ31_RS38315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ31_RS38335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ31_RS38350	COG0395	ABC-type sugar transport system, permease component
DDJ31_RS38365	COG0477	Major facilitator Superfamily
DDJ31_RS38375	COG1522	sequence-specific DNA binding
DDJ31_RS38385	COG0235	Class ii aldolase
DDJ31_RS38390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDJ31_RS38410	COG0019	diaminopimelate decarboxylase activity
DDJ31_RS38415	COG1607	acyl-coa hydrolase
DDJ31_RS38430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDJ31_RS38455	COG1917	Cupin 2, conserved barrel domain protein
DDJ31_RS38460	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDJ31_RS38470	COG5285	phytanoyl-CoA dioxygenase
DDJ31_RS38495	COG0640	Transcriptional regulator
DDJ31_RS38520	COG0431	NADPH-dependent FMN reductase
DDJ31_RS38535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDJ31_RS38555	COG0477	Major facilitator Superfamily
DDJ31_RS38565	COG1309	transcriptional regulator
DDJ31_RS38575	COG2814	Major facilitator Superfamily
DDJ31_RS38590	COG2814	Major facilitator Superfamily