locus-tag	class	description
SGR_RS00140	COG2801	Transposase and inactivated derivatives
SGR_RS00150	COG1335	isochorismatase
SGR_RS00170	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SGR_RS00245	COG1309	transcriptional regulator
SGR_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS00285	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGR_RS00305	COG0142	geranyltranstransferase activity
SGR_RS00320	COG2837	iron assimilation
SGR_RS00345	COG0477	Major facilitator Superfamily
SGR_RS00350	COG0431	NADPH-dependent FMN reductase
SGR_RS00530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SGR_RS00555	COG3293	Transposase
SGR_RS00645	COG1309	transcriptional regulator
SGR_RS00665	COG2188	Transcriptional regulator
SGR_RS00670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SGR_RS00675	COG1869	D-ribose catabolic process
SGR_RS00680	COG1129	ABC transporter
SGR_RS00690	COG1172	Belongs to the binding-protein-dependent transport system permease family
SGR_RS00695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGR_RS00705	COG0515	serine threonine protein kinase
SGR_RS00725	COG1162	GTPase activity
SGR_RS00730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SGR_RS00765	COG0778	Nitroreductase
SGR_RS00785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGR_RS00795	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SGR_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS00835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGR_RS00850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS00915	COG2197	response regulator
SGR_RS00920	COG4585	Histidine kinase
SGR_RS00925	COG2409	Drug exporters of the RND superfamily
SGR_RS00930	COG1802	Transcriptional regulator
SGR_RS00935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGR_RS00950	COG0395	ABC-type sugar transport system, permease component
SGR_RS00970	COG1653	transport
SGR_RS00975	COG3866	Pectate lyase
SGR_RS00990	COG1309	transcriptional regulator
SGR_RS01000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SGR_RS01025	COG4213	ABC transporter substrate-binding protein
SGR_RS01035	COG4214	carbohydrate transport
SGR_RS01040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGR_RS01065	COG0829	nickel cation binding
SGR_RS01070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SGR_RS01085	COG0831	urea catabolic process
SGR_RS01095	COG1595	DNA-templated transcription, initiation
SGR_RS01115	COG1404	Belongs to the peptidase S8 family
SGR_RS01125	COG2205	protein histidine kinase activity
SGR_RS01130	COG0745	RESPONSE REGULATOR receiver
SGR_RS01135	COG2226	methyltransferase
SGR_RS01150	COG2226	methyltransferase
SGR_RS01190	COG0596	Alpha beta hydrolase
SGR_RS01200	COG0586	Pfam SNARE associated Golgi protein
SGR_RS01240	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SGR_RS01250	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SGR_RS01255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS01265	COG0745	RESPONSE REGULATOR receiver
SGR_RS01270	COG2205	protein histidine kinase activity
SGR_RS01300	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SGR_RS01305	COG0714	Associated with various cellular activities
SGR_RS01315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGR_RS01325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGR_RS01330	COG0395	ABC-type sugar transport system, permease component
SGR_RS01345	COG1609	Transcriptional regulator
SGR_RS01360	COG2318	DinB family
SGR_RS01375	COG1910	domain protein
SGR_RS01400	COG0009	L-threonylcarbamoyladenylate synthase
SGR_RS01420	COG0488	(ABC) transporter
SGR_RS01460	COG2340	Cysteine-rich secretory protein family
SGR_RS01475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SGR_RS01480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SGR_RS01495	COG1595	DNA-templated transcription, initiation
SGR_RS01525	COG1357	PFAM Pentapeptide repeats (8 copies)
SGR_RS01540	COG1024	Enoyl-CoA hydratase
SGR_RS01570	COG2018	Roadblock/LC7 domain
SGR_RS01585	COG0640	Transcriptional regulator
SGR_RS01590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGR_RS01625	COG3239	Fatty acid desaturase
SGR_RS01630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SGR_RS01650	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS01685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS01690	COG0601	transmembrane transport
SGR_RS01700	COG4608	Belongs to the ABC transporter superfamily
SGR_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS01715	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SGR_RS01720	COG2318	DinB family
SGR_RS01755	COG2814	Major facilitator Superfamily
SGR_RS01855	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SGR_RS01860	COG3118	belongs to the thioredoxin family
SGR_RS01865	COG1115	amino acid carrier protein
SGR_RS01870	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS01885	COG0745	RESPONSE REGULATOR receiver
SGR_RS01915	COG2124	cytochrome p450
SGR_RS01925	COG1309	transcriptional regulator
SGR_RS01935	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS01965	COG2124	cytochrome p450
SGR_RS01975	COG0110	maltose O-acetyltransferase activity
SGR_RS02015	COG1960	acyl-CoA dehydrogenase activity
SGR_RS02020	COG0789	Transcriptional regulator
SGR_RS02050	COG1175	transmembrane transport
SGR_RS02060	COG1063	alcohol dehydrogenase
SGR_RS02075	COG4044	May play a role in the intracellular transport of hydrophobic ligands
SGR_RS02080	COG1132	(ABC) transporter
SGR_RS02100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGR_RS02115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGR_RS02130	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS02135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS02140	COG2375	cellular response to nickel ion
SGR_RS02155	COG0693	protein deglycase activity
SGR_RS02160	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SGR_RS02175	COG1278	Cold shock
SGR_RS02240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SGR_RS02280	COG1796	DNA polymerase
SGR_RS02280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SGR_RS02340	COG0444	Belongs to the ABC transporter superfamily
SGR_RS02345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS02350	COG0601	transmembrane transport
SGR_RS02365	COG1960	acyl-CoA dehydrogenase activity
SGR_RS02370	COG1960	acyl-CoA dehydrogenase activity
SGR_RS02390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SGR_RS02400	COG0517	IMP dehydrogenase activity
SGR_RS02400	COG1125	glycine betaine transport
SGR_RS02405	COG0656	L-ascorbic acid biosynthetic process
SGR_RS02425	COG1174	glycine betaine transport
SGR_RS02430	COG1174	glycine betaine transport
SGR_RS02450	COG0297	glycogen (starch) synthase activity
SGR_RS02450	COG0438	transferase activity, transferring glycosyl groups
SGR_RS02455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGR_RS02475	COG0438	transferase activity, transferring glycosyl groups
SGR_RS02495	COG2304	oxidoreductase activity
SGR_RS02520	COG1132	(ABC) transporter
SGR_RS02525	COG1132	(ABC) transporter
SGR_RS02550	COG1120	ATPase activity
SGR_RS02555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS02560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS02575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SGR_RS02580	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SGR_RS02585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SGR_RS02590	COG0254	rRNA binding
SGR_RS02600	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGR_RS02605	COG0477	Major facilitator Superfamily
SGR_RS02615	COG1120	ATPase activity
SGR_RS02665	COG0156	8-amino-7-oxononanoate synthase activity
SGR_RS02675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGR_RS02680	COG4569	acetaldehyde dehydrogenase (acetylating) activity
SGR_RS02695	COG1309	transcriptional regulator
SGR_RS02700	COG0275	rRNA processing
SGR_RS02705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SGR_RS02765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGR_RS02765	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SGR_RS02775	COG2226	methyltransferase
SGR_RS02795	COG1132	(ABC) transporter
SGR_RS02835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGR_RS02860	COG2207	Transcriptional regulator
SGR_RS02860	COG3708	Transcriptional regulator
SGR_RS02895	COG0604	alcohol dehydrogenase
SGR_RS02895	COG3321	synthase
SGR_RS02950	COG0477	Major facilitator Superfamily
SGR_RS02955	COG3795	YCII-related domain
SGR_RS02980	COG0596	Alpha beta hydrolase
SGR_RS02990	COG1960	acyl-CoA dehydrogenase activity
SGR_RS02995	COG4941	Belongs to the sigma-70 factor family
SGR_RS03000	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SGR_RS03015	COG1960	acyl-CoA dehydrogenase activity
SGR_RS03040	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SGR_RS03050	COG0793	Belongs to the peptidase S41A family
SGR_RS03110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGR_RS03150	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS03175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SGR_RS03205	COG1834	amidinotransferase
SGR_RS03210	COG0697	spore germination
SGR_RS03220	COG2045	Belongs to the ComB family
SGR_RS03245	COG0326	Molecular chaperone. Has ATPase activity
SGR_RS03260	COG2066	Belongs to the glutaminase family
SGR_RS03285	COG3547	Transposase (IS116 IS110 IS902 family)
SGR_RS03290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGR_RS03295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SGR_RS03305	COG1609	Transcriptional regulator
SGR_RS03325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SGR_RS03330	COG0121	glutamine amidotransferase
SGR_RS03335	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SGR_RS03355	COG3360	Dodecin
SGR_RS03365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS03375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SGR_RS03380	COG1053	succinate dehydrogenase
SGR_RS03390	COG0583	DNA-binding transcription factor activity
SGR_RS03460	COG3275	phosphorelay sensor kinase activity
SGR_RS03465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGR_RS03480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGR_RS03520	COG1191	sigma factor activity
SGR_RS03530	COG4251	negative regulation of phosphorylation
SGR_RS03535	COG0784	Response regulator, receiver
SGR_RS03580	COG1652	LysM domain
SGR_RS03595	COG1940	carbohydrate kinase activity
SGR_RS03605	COG1175	transmembrane transport
SGR_RS03610	COG0395	ABC-type sugar transport system, permease component
SGR_RS03615	COG2723	6-phospho-beta-galactosidase activity
SGR_RS03675	COG1595	DNA-templated transcription, initiation
SGR_RS03685	COG1119	ATPase activity
SGR_RS03695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SGR_RS03705	COG2837	iron assimilation
SGR_RS03715	COG0019	diaminopimelate decarboxylase activity
SGR_RS03725	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SGR_RS03730	COG2376	Dihydroxyacetone kinase
SGR_RS03735	COG2376	Dihydroxyacetone kinase
SGR_RS03750	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SGR_RS03755	COG1228	amidohydrolase
SGR_RS03775	COG1007	ATP synthesis coupled electron transport
SGR_RS03785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGR_RS03800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SGR_RS03810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGR_RS03815	COG2186	Transcriptional regulator
SGR_RS03820	COG1620	l-lactate permease
SGR_RS03825	COG0247	lactate metabolic process
SGR_RS03830	COG1139	Iron-sulfur cluster binding protein
SGR_RS03835	COG1556	Lactate utilization protein
SGR_RS03875	COG2188	Transcriptional regulator
SGR_RS03890	COG0395	ABC-type sugar transport system, permease component
SGR_RS03895	COG4948	Mandelate Racemase Muconate Lactonizing
SGR_RS03905	COG2130	NADP-dependent
SGR_RS03910	COG1233	COG1233 Phytoene dehydrogenase and related
SGR_RS03955	COG1846	Transcriptional regulator
SGR_RS03960	COG2409	Drug exporters of the RND superfamily
SGR_RS03975	COG1902	pentaerythritol trinitrate reductase activity
SGR_RS03975	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGR_RS04000	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS04010	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SGR_RS04030	COG1414	Transcriptional regulator
SGR_RS04035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGR_RS04045	COG3833	ABC-type maltose transport systems, permease component
SGR_RS04065	COG0829	nickel cation binding
SGR_RS04070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SGR_RS04075	COG0830	nickel cation binding
SGR_RS04080	COG0804	urea catabolic process
SGR_RS04105	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SGR_RS04110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SGR_RS04125	COG0667	Aldo Keto reductase
SGR_RS04160	COG1733	regulation of RNA biosynthetic process
SGR_RS04165	COG0640	Transcriptional regulator
SGR_RS04175	COG2208	phosphoserine phosphatase activity
SGR_RS04215	COG2197	response regulator
SGR_RS04230	COG1131	(ABC) transporter
SGR_RS04240	COG1672	PFAM Archaeal ATPase
SGR_RS04240	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SGR_RS04270	COG3851	Histidine kinase
SGR_RS04275	COG2197	response regulator
SGR_RS04285	COG3511	phospholipase C
SGR_RS04310	COG0714	Associated with various cellular activities
SGR_RS04345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGR_RS04360	COG0477	Major facilitator Superfamily
SGR_RS04410	COG3251	PFAM MbtH domain protein
SGR_RS04460	COG3959	Transketolase, thiamine diphosphate binding domain
SGR_RS04465	COG3958	Transketolase
SGR_RS04490	COG1116	anion transmembrane transporter activity
SGR_RS04500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGR_RS04505	COG1609	Transcriptional regulator
SGR_RS04560	COG0789	Transcriptional regulator
SGR_RS04575	COG3467	pyridoxamine 5'-phosphate
SGR_RS04615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGR_RS04625	COG2755	lipolytic protein G-D-S-L family
SGR_RS04630	COG0739	heme binding
SGR_RS04635	COG2365	Tyrosine phosphatase family
SGR_RS04660	COG1657	PFAM Prenyltransferase squalene oxidase
SGR_RS04670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SGR_RS04680	COG1562	ergosterol biosynthetic process
SGR_RS04685	COG1134	teichoic acid transport
SGR_RS04705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGR_RS04730	COG2226	methyltransferase
SGR_RS04735	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SGR_RS04750	COG1024	Enoyl-CoA hydratase
SGR_RS04760	COG4977	sequence-specific DNA binding
SGR_RS04770	COG2183	response to ionizing radiation
SGR_RS04785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SGR_RS04810	COG0789	Transcriptional regulator
SGR_RS04815	COG1024	Enoyl-CoA hydratase
SGR_RS04815	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGR_RS04820	COG0183	Belongs to the thiolase family
SGR_RS04825	COG1960	acyl-CoA dehydrogenase activity
SGR_RS04830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SGR_RS04835	COG3268	Saccharopine dehydrogenase
SGR_RS04840	COG1515	deoxyribonuclease V activity
SGR_RS04875	COG0488	(ABC) transporter
SGR_RS04880	COG2267	carboxylic ester hydrolase activity
SGR_RS04885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SGR_RS04905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS04910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGR_RS04915	COG1116	anion transmembrane transporter activity
SGR_RS04920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGR_RS04970	COG1793	dna ligase
SGR_RS04975	COG2326	polyphosphate kinase activity
SGR_RS05045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SGR_RS05090	COG1960	acyl-CoA dehydrogenase activity
SGR_RS05105	COG3012	SEC-C Motif Domain Protein
SGR_RS05135	COG1486	melibiose metabolic process
SGR_RS05140	COG2124	cytochrome p450
SGR_RS05165	COG1846	Transcriptional regulator
SGR_RS05190	COG1940	carbohydrate kinase activity
SGR_RS05200	COG1070	Carbohydrate kinase
SGR_RS05210	COG0488	(ABC) transporter
SGR_RS05230	COG0569	domain protein
SGR_RS05230	COG2985	domain, Protein
SGR_RS05240	COG2124	cytochrome p450
SGR_RS05250	COG4176	ABC-type proline glycine betaine transport system permease component
SGR_RS05255	COG0517	IMP dehydrogenase activity
SGR_RS05255	COG4175	Glycine betaine
SGR_RS05265	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS05280	COG0745	RESPONSE REGULATOR receiver
SGR_RS05285	COG5002	protein histidine kinase activity
SGR_RS05300	COG3568	Endonuclease Exonuclease Phosphatase
SGR_RS05310	COG1869	D-ribose catabolic process
SGR_RS05315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGR_RS05325	COG1129	ABC transporter
SGR_RS05345	COG0494	nUDIX hydrolase
SGR_RS05355	COG1349	DNA-binding transcription factor activity
SGR_RS05360	COG2267	carboxylic ester hydrolase activity
SGR_RS05390	COG0084	hydrolase, TatD family'
SGR_RS05405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SGR_RS05425	COG0673	inositol 2-dehydrogenase activity
SGR_RS05430	COG1879	ABC-type sugar transport system periplasmic component
SGR_RS05435	COG1172	Belongs to the binding-protein-dependent transport system permease family
SGR_RS05440	COG1129	ABC transporter
SGR_RS05450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGR_RS05455	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SGR_RS05480	COG0656	L-ascorbic acid biosynthetic process
SGR_RS05490	COG4106	trans-aconitate 2-methyltransferase activity
SGR_RS05500	COG0702	epimerase
SGR_RS05505	COG0583	DNA-binding transcription factor activity
SGR_RS05510	COG2154	pterin-4-alpha-carbinolamine dehydratase
SGR_RS05520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGR_RS05520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGR_RS05535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGR_RS05580	COG2226	methyltransferase
SGR_RS05610	COG1619	proteins homologs of microcin C7 resistance protein MccF
SGR_RS05620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGR_RS05625	COG2362	D-Aminopeptidase
SGR_RS05640	COG0667	Aldo Keto reductase
SGR_RS05645	COG0583	DNA-binding transcription factor activity
SGR_RS05670	COG0596	Alpha beta hydrolase
SGR_RS05680	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGR_RS05700	COG0604	alcohol dehydrogenase
SGR_RS05705	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGR_RS05705	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGR_RS05710	COG2301	Belongs to the HpcH HpaI aldolase family
SGR_RS05720	COG1960	acyl-CoA dehydrogenase activity
SGR_RS05725	COG0688	phosphatidylethanolamine metabolic process
SGR_RS05765	COG0559	Belongs to the binding-protein-dependent transport system permease family
SGR_RS05770	COG0559	Belongs to the binding-protein-dependent transport system permease family
SGR_RS05790	COG1929	Belongs to the glycerate kinase type-1 family
SGR_RS05825	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS05850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGR_RS05895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SGR_RS05910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SGR_RS05935	COG1024	Enoyl-CoA hydratase
SGR_RS05950	COG0095	Lipoate-protein ligase
SGR_RS05970	COG2838	Isocitrate dehydrogenase
SGR_RS05975	COG1191	sigma factor activity
SGR_RS05995	COG1953	Uracil, thiamine, allantoin
SGR_RS06005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGR_RS06010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SGR_RS06045	COG0405	Gamma-glutamyltransferase
SGR_RS06050	COG4221	oxidoreductase activity
SGR_RS06065	COG0640	Transcriptional regulator
SGR_RS06075	COG3548	integral membrane protein
SGR_RS06090	COG0765	amino acid transport
SGR_RS06095	COG0765	amino acid transport
SGR_RS06100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS06105	COG1126	abc transporter atp-binding protein
SGR_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS06130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SGR_RS06135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGR_RS06155	COG1132	(ABC) transporter
SGR_RS06160	COG0494	nUDIX hydrolase
SGR_RS06165	COG1937	Protein conserved in bacteria
SGR_RS06180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SGR_RS06180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SGR_RS06185	COG0785	Cytochrome C biogenesis protein
SGR_RS06205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SGR_RS06215	COG1940	carbohydrate kinase activity
SGR_RS06220	COG1129	ABC transporter
SGR_RS06230	COG1879	ABC-type sugar transport system periplasmic component
SGR_RS06235	COG2188	Transcriptional regulator
SGR_RS06240	COG0673	inositol 2-dehydrogenase activity
SGR_RS06255	COG2197	response regulator
SGR_RS06280	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS06285	COG0656	L-ascorbic acid biosynthetic process
SGR_RS06295	COG4266	Belongs to the allantoicase family
SGR_RS06300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGR_RS06305	COG1414	Transcriptional regulator
SGR_RS06325	COG2197	response regulator
SGR_RS06335	COG0746	molybdenum cofactor guanylyltransferase activity
SGR_RS06340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SGR_RS06380	COG2233	PERMEase
SGR_RS06390	COG2233	PERMEase
SGR_RS06400	COG2351	hydroxyisourate hydrolase activity
SGR_RS06420	COG2706	6-phosphogluconolactonase activity
SGR_RS06425	COG2188	Transcriptional regulator
SGR_RS06430	COG2182	Extracellular solute-binding protein
SGR_RS06435	COG1175	transmembrane transport
SGR_RS06440	COG0395	ABC-type sugar transport system, permease component
SGR_RS06445	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SGR_RS06450	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SGR_RS06455	COG3622	Belongs to the hyi family
SGR_RS06460	COG2084	Dehydrogenase
SGR_RS06465	COG0753	catalase activity
SGR_RS06495	COG3960	tartronate-semialdehyde synthase activity
SGR_RS06515	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS06520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SGR_RS06525	COG2197	response regulator
SGR_RS06540	COG0435	Glutathione S-transferase
SGR_RS06570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGR_RS06605	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SGR_RS06605	COG3608	succinylglutamate desuccinylase aspartoacylase
SGR_RS06610	COG2252	PERMEase
SGR_RS06615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SGR_RS06640	COG1802	Transcriptional regulator
SGR_RS06670	COG0028	Belongs to the TPP enzyme family
SGR_RS06695	COG1162	GTPase activity
SGR_RS06745	COG0183	Belongs to the thiolase family
SGR_RS06750	COG0583	DNA-binding transcription factor activity
SGR_RS06755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SGR_RS06760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SGR_RS06765	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGR_RS06785	COG1960	acyl-CoA dehydrogenase activity
SGR_RS06810	COG0175	sulfate reduction
SGR_RS06815	COG0529	Catalyzes the synthesis of activated sulfate
SGR_RS06840	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SGR_RS06845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGR_RS06855	COG2226	methyltransferase
SGR_RS06865	COG1120	ATPase activity
SGR_RS06870	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS06875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS06880	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SGR_RS06890	COG1132	(ABC) transporter
SGR_RS06925	COG1175	transmembrane transport
SGR_RS07000	COG2723	6-phospho-beta-galactosidase activity
SGR_RS07010	COG0667	Aldo Keto reductase
SGR_RS07020	COG1072	(Pantothenic acid kinase))
SGR_RS07025	COG0346	lactoylglutathione lyase activity
SGR_RS07030	COG2197	response regulator
SGR_RS07040	COG1136	(ABC) transporter
SGR_RS07055	COG0583	DNA-binding transcription factor activity
SGR_RS07060	COG0156	8-amino-7-oxononanoate synthase activity
SGR_RS07065	COG1063	alcohol dehydrogenase
SGR_RS07070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SGR_RS07070	COG0515	serine threonine protein kinase
SGR_RS07115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SGR_RS07120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SGR_RS07170	COG3220	belongs to the UPF0276 family
SGR_RS07185	COG3253	May function as heme-dependent peroxidase
SGR_RS07190	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SGR_RS07200	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGR_RS07205	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SGR_RS07225	COG0183	Belongs to the thiolase family
SGR_RS07230	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGR_RS07230	COG1024	Enoyl-CoA hydratase
SGR_RS07240	COG0438	transferase activity, transferring glycosyl groups
SGR_RS07250	COG0438	transferase activity, transferring glycosyl groups
SGR_RS07265	COG1316	TRANSCRIPTIONal
SGR_RS07300	COG1505	serine-type exopeptidase activity
SGR_RS07305	COG0531	amino acid
SGR_RS07310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SGR_RS07315	COG4214	carbohydrate transport
SGR_RS07325	COG4213	ABC transporter substrate-binding protein
SGR_RS07330	COG1940	carbohydrate kinase activity
SGR_RS07335	COG0395	ABC-type sugar transport system, permease component
SGR_RS07340	COG1175	transmembrane transport
SGR_RS07345	COG1653	transport
SGR_RS07355	COG0406	alpha-ribazole phosphatase activity
SGR_RS07365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SGR_RS07385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGR_RS07420	COG2226	methyltransferase
SGR_RS07425	COG1132	(ABC) transporter
SGR_RS07480	COG1129	ABC transporter
SGR_RS07500	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS07520	COG2172	sigma factor antagonist activity
SGR_RS07520	COG2208	phosphoserine phosphatase activity
SGR_RS07520	COG1366	Belongs to the anti-sigma-factor antagonist family
SGR_RS07535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGR_RS07540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGR_RS07545	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SGR_RS07565	COG0438	transferase activity, transferring glycosyl groups
SGR_RS07580	COG0489	protein tyrosine kinase activity
SGR_RS07585	COG0297	glycogen (starch) synthase activity
SGR_RS07605	COG1320	monovalent cation:proton antiporter activity
SGR_RS07620	COG0651	ATP synthesis coupled electron transport
SGR_RS07625	COG1006	Multisubunit Na H antiporter MnhC subunit
SGR_RS07630	COG2111	Na H antiporter
SGR_RS07630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGR_RS07675	COG1024	Enoyl-CoA hydratase
SGR_RS07685	COG0531	amino acid
SGR_RS07690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SGR_RS07700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SGR_RS07710	COG2040	homocysteine
SGR_RS07730	COG1799	cell septum assembly
SGR_RS07735	COG1349	DNA-binding transcription factor activity
SGR_RS07740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGR_RS07745	COG0586	Pfam SNARE associated Golgi protein
SGR_RS07755	COG2375	cellular response to nickel ion
SGR_RS07755	COG1132	(ABC) transporter
SGR_RS07775	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS07780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS07810	COG3046	protein related to deoxyribodipyrimidine photolyase
SGR_RS07880	COG1201	RNA secondary structure unwinding
SGR_RS07885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGR_RS07890	COG1280	lysine exporter protein (LysE YggA)
SGR_RS07900	COG3291	Pkd domain containing protein
SGR_RS07905	COG4608	Belongs to the ABC transporter superfamily
SGR_RS07910	COG0444	Belongs to the ABC transporter superfamily
SGR_RS07915	COG0601	transmembrane transport
SGR_RS07920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS07925	COG0747	negative chemotaxis
SGR_RS07930	COG0006	proline dipeptidase activity
SGR_RS07935	COG1802	Transcriptional regulator
SGR_RS07945	COG3938	Belongs to the proline racemase family
SGR_RS07950	COG3938	Belongs to the proline racemase family
SGR_RS07960	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGR_RS07970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGR_RS08020	COG0539	negative regulation of cytoplasmic translation
SGR_RS08040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SGR_RS08070	COG3845	ABC transporter
SGR_RS08085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGR_RS08090	COG0531	amino acid
SGR_RS08095	COG0569	domain protein
SGR_RS08125	COG4591	ABC-type transport system involved in lipoprotein release permease component
SGR_RS08125	COG1136	(ABC) transporter
SGR_RS08135	COG0756	dUTP diphosphatase activity
SGR_RS08160	COG2205	protein histidine kinase activity
SGR_RS08165	COG0745	RESPONSE REGULATOR receiver
SGR_RS08175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SGR_RS08210	COG1435	thymidine kinase activity
SGR_RS08225	COG0045	succinate-CoA ligase (ADP-forming) activity
SGR_RS08225	COG1042	CoA-binding domain protein
SGR_RS08225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGR_RS08230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGR_RS08235	COG1802	Transcriptional regulator
SGR_RS08250	COG0612	Peptidase, M16
SGR_RS08255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGR_RS08265	COG0372	Belongs to the citrate synthase family
SGR_RS08270	COG0372	Belongs to the citrate synthase family
SGR_RS08280	COG3290	protein histidine kinase activity
SGR_RS08285	COG4565	transcriptional regulatory protein
SGR_RS08290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGR_RS08315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGR_RS08320	COG2186	Transcriptional regulator
SGR_RS08355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGR_RS08385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGR_RS08390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SGR_RS08395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SGR_RS08430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SGR_RS08440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SGR_RS08445	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SGR_RS08455	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SGR_RS08470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGR_RS08475	COG2358	TRAP transporter, solute receptor (TAXI family
SGR_RS08480	COG2205	protein histidine kinase activity
SGR_RS08485	COG0745	RESPONSE REGULATOR receiver
SGR_RS08495	COG1126	abc transporter atp-binding protein
SGR_RS08500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS08505	COG0765	amino acid transport
SGR_RS08510	COG0765	amino acid transport
SGR_RS08515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGR_RS08525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SGR_RS08540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SGR_RS08550	COG0640	Transcriptional regulator
SGR_RS08555	COG0798	PFAM Bile acid sodium symporter
SGR_RS08560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGR_RS08605	COG1917	Cupin 2, conserved barrel domain protein
SGR_RS08605	COG2207	Transcriptional regulator
SGR_RS08610	COG1201	RNA secondary structure unwinding
SGR_RS08615	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGR_RS08620	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS08630	COG0783	Belongs to the Dps family
SGR_RS08635	COG1396	sequence-specific DNA binding
SGR_RS08640	COG1546	Belongs to the CinA family
SGR_RS08640	COG1058	Belongs to the CinA family
SGR_RS08650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGR_RS08660	COG1674	ftsk spoiiie
SGR_RS08670	COG2205	protein histidine kinase activity
SGR_RS08670	COG4999	Histidine kinase
SGR_RS08670	COG3437	response regulator, receiver
SGR_RS08670	COG3850	Histidine kinase
SGR_RS08675	COG2208	phosphoserine phosphatase activity
SGR_RS08675	COG2770	Histidine kinase
SGR_RS08700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SGR_RS08705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGR_RS08710	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SGR_RS08730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SGR_RS08735	COG0612	Peptidase, M16
SGR_RS08740	COG1185	polyribonucleotide nucleotidyltransferase activity
SGR_RS08745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SGR_RS08755	COG1674	ftsk spoiiie
SGR_RS08770	COG4935	Belongs to the peptidase S8 family
SGR_RS08770	COG1404	Belongs to the peptidase S8 family
SGR_RS08785	COG1404	Belongs to the peptidase S8 family
SGR_RS08790	COG3266	domain, Protein
SGR_RS08810	COG0455	bacterial-type flagellum organization
SGR_RS08815	COG0747	negative chemotaxis
SGR_RS08820	COG0601	transmembrane transport
SGR_RS08825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS08865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SGR_RS08870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SGR_RS08880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SGR_RS08895	COG0779	Required for maturation of 30S ribosomal subunits
SGR_RS08915	COG0442	prolyl-tRNA aminoacylation
SGR_RS08930	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SGR_RS08935	COG0750	zinc metalloprotease
SGR_RS08940	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SGR_RS08945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGR_RS08955	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS08960	COG2508	Transcriptional regulator
SGR_RS08990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGR_RS08995	COG1177	transmembrane transport
SGR_RS09000	COG1176	ABC-type spermidine putrescine transport system, permease component I
SGR_RS09005	COG3842	ATPase activity
SGR_RS09010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SGR_RS09030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGR_RS09050	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS09060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SGR_RS09095	COG2197	response regulator
SGR_RS09100	COG3842	ATPase activity
SGR_RS09115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SGR_RS09120	COG0575	Belongs to the CDS family
SGR_RS09125	COG0233	cytoplasmic translational termination
SGR_RS09130	COG0528	UMP kinase activity
SGR_RS09135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SGR_RS09140	COG0052	Belongs to the universal ribosomal protein uS2 family
SGR_RS09155	COG1191	sigma factor activity
SGR_RS09200	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
SGR_RS09210	COG0792	nuclease activity
SGR_RS09225	COG0681	Belongs to the peptidase S26 family
SGR_RS09230	COG0681	Belongs to the peptidase S26 family
SGR_RS09245	COG0335	large ribosomal subunit rRNA binding
SGR_RS09250	COG0336	Belongs to the RNA methyltransferase TrmD family
SGR_RS09255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SGR_RS09260	COG1837	Belongs to the UPF0109 family
SGR_RS09265	COG0228	four-way junction DNA binding
SGR_RS09285	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SGR_RS09320	COG0477	Major facilitator Superfamily
SGR_RS09325	COG1196	nuclear chromosome segregation
SGR_RS09335	COG1254	Belongs to the acylphosphatase family
SGR_RS09340	COG2340	Cysteine-rich secretory protein family
SGR_RS09350	COG1733	regulation of RNA biosynthetic process
SGR_RS09355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGR_RS09360	COG0571	ribonuclease III activity
SGR_RS09365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SGR_RS09380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SGR_RS09385	COG0742	ribosomal rna small subunit methyltransferase
SGR_RS09390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SGR_RS09395	COG1461	Dihydroxyacetone kinase
SGR_RS09400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SGR_RS09405	COG0351	phosphomethylpyrimidine kinase
SGR_RS09425	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGR_RS09430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SGR_RS09440	COG1920	GTP binding
SGR_RS09450	COG0776	regulation of translation
SGR_RS09460	COG0066	3-isopropylmalate dehydratase activity
SGR_RS09465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SGR_RS09470	COG1414	Transcriptional regulator
SGR_RS09505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SGR_RS09510	COG0179	Fumarylacetoacetate (FAA) hydrolase
SGR_RS09520	COG5002	protein histidine kinase activity
SGR_RS09525	COG2018	Roadblock/LC7 domain
SGR_RS09545	COG2018	Roadblock/LC7 domain
SGR_RS09565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGR_RS09570	COG1470	cell adhesion involved in biofilm formation
SGR_RS09570	COG0366	Alpha amylase catalytic
SGR_RS09595	COG4607	ABC-type enterochelin transport system periplasmic component
SGR_RS09600	COG1120	ATPase activity
SGR_RS09605	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS09610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS09630	COG0494	nUDIX hydrolase
SGR_RS09645	COG0492	ferredoxin-NADP+ reductase activity
SGR_RS09655	COG3708	Transcriptional regulator
SGR_RS09655	COG2207	Transcriptional regulator
SGR_RS09665	COG1309	transcriptional regulator
SGR_RS09705	COG0444	Belongs to the ABC transporter superfamily
SGR_RS09710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS09715	COG0601	transmembrane transport
SGR_RS09720	COG4608	Belongs to the ABC transporter superfamily
SGR_RS09730	COG1609	Transcriptional regulator
SGR_RS09735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGR_RS09745	COG2957	Belongs to the agmatine deiminase family
SGR_RS09750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SGR_RS09755	COG0473	3-isopropylmalate dehydrogenase activity
SGR_RS09770	COG0778	Nitroreductase
SGR_RS09770	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SGR_RS09775	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS09780	COG0506	proline dehydrogenase activity
SGR_RS09785	COG2508	Transcriptional regulator
SGR_RS09790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGR_RS09820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SGR_RS09825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SGR_RS09830	COG0440	acetolactate synthase activity
SGR_RS09860	COG3835	regulator
SGR_RS09865	COG0667	Aldo Keto reductase
SGR_RS09870	COG2133	pyrroloquinoline quinone binding
SGR_RS09880	COG2197	response regulator
SGR_RS09895	COG2409	Drug exporters of the RND superfamily
SGR_RS09910	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGR_RS09920	COG0154	amidase activity
SGR_RS09925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGR_RS09935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGR_RS09945	COG4221	oxidoreductase activity
SGR_RS09965	COG0482	sulfurtransferase activity
SGR_RS10000	COG0789	Transcriptional regulator
SGR_RS10010	COG2860	membrane
SGR_RS10015	COG4608	Belongs to the ABC transporter superfamily
SGR_RS10025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS10030	COG0601	transmembrane transport
SGR_RS10035	COG0747	negative chemotaxis
SGR_RS10055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SGR_RS10060	COG0509	glycine decarboxylation via glycine cleavage system
SGR_RS10065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SGR_RS10070	COG1760	l-serine dehydratase
SGR_RS10105	COG0464	growth
SGR_RS10115	COG0823	Involved in the tonB-independent uptake of proteins
SGR_RS10115	COG1506	peptidase
SGR_RS10275	COG1132	(ABC) transporter
SGR_RS10280	COG1132	(ABC) transporter
SGR_RS10305	COG0058	SHG alpha-glucan phosphorylase activity
SGR_RS10310	COG0366	Alpha amylase catalytic
SGR_RS10315	COG0366	Alpha amylase catalytic
SGR_RS10320	COG3281	Trehalose synthase
SGR_RS10325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SGR_RS10335	COG3118	belongs to the thioredoxin family
SGR_RS10350	COG1301	dicarboxylic acid transport
SGR_RS10355	COG3290	protein histidine kinase activity
SGR_RS10360	COG4565	transcriptional regulatory protein
SGR_RS10370	COG0205	6-phosphofructokinase activity
SGR_RS10375	COG0857	belongs to the CobB CobQ family
SGR_RS10375	COG0280	phosphate acetyltransferase
SGR_RS10380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SGR_RS10415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGR_RS10415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGR_RS10485	COG5002	protein histidine kinase activity
SGR_RS10485	COG5000	phosphorelay sensor kinase activity
SGR_RS10505	COG0183	Belongs to the thiolase family
SGR_RS10525	COG1131	(ABC) transporter
SGR_RS10560	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SGR_RS10575	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGR_RS10605	COG4585	Histidine kinase
SGR_RS10610	COG2197	response regulator
SGR_RS10625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SGR_RS10630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SGR_RS10635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SGR_RS10640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SGR_RS10645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGR_RS10650	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SGR_RS10655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGR_RS10675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SGR_RS10680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGR_RS10690	COG2890	protein-(glutamine-N5) methyltransferase activity
SGR_RS10695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SGR_RS10700	COG0254	rRNA binding
SGR_RS10705	COG1316	TRANSCRIPTIONal
SGR_RS10715	COG0083	homoserine kinase activity
SGR_RS10720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SGR_RS10725	COG0460	homoserine dehydrogenase
SGR_RS10730	COG0019	diaminopimelate decarboxylase activity
SGR_RS10735	COG0018	arginyl-trna synthetase
SGR_RS10775	COG3629	intracellular signal transduction
SGR_RS10775	COG3903	Transcriptional regulator
SGR_RS10790	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SGR_RS10795	COG1793	dna ligase
SGR_RS10795	COG3285	dna ligase
SGR_RS10815	COG2205	protein histidine kinase activity
SGR_RS10830	COG0768	penicillin binding
SGR_RS10860	COG1309	transcriptional regulator
SGR_RS10920	COG0726	polysaccharide deacetylase
SGR_RS10925	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SGR_RS10935	COG0745	RESPONSE REGULATOR receiver
SGR_RS10940	COG2205	protein histidine kinase activity
SGR_RS10945	COG0567	Dehydrogenase, E1 component
SGR_RS10945	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGR_RS10990	COG0604	alcohol dehydrogenase
SGR_RS10995	COG0281	malic enzyme
SGR_RS11000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS11005	COG0765	amino acid transport
SGR_RS11010	COG1126	abc transporter atp-binding protein
SGR_RS11020	COG1595	DNA-templated transcription, initiation
SGR_RS11025	COG4106	trans-aconitate 2-methyltransferase activity
SGR_RS11060	COG4585	Histidine kinase
SGR_RS11130	COG0142	geranyltranstransferase activity
SGR_RS11135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SGR_RS11140	COG1959	2 iron, 2 sulfur cluster binding
SGR_RS11165	COG2172	sigma factor antagonist activity
SGR_RS11180	COG1597	lipid kinase activity
SGR_RS11195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGR_RS11200	COG0363	glucosamine-6-phosphate deaminase activity
SGR_RS11205	COG1472	Belongs to the glycosyl hydrolase 3 family
SGR_RS11210	COG0395	ABC-type sugar transport system, permease component
SGR_RS11215	COG1175	transmembrane transport
SGR_RS11220	COG2182	Extracellular solute-binding protein
SGR_RS11230	COG0667	Aldo Keto reductase
SGR_RS11250	COG1215	transferase activity, transferring glycosyl groups
SGR_RS11260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGR_RS11265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGR_RS11275	COG1215	transferase activity, transferring glycosyl groups
SGR_RS11290	COG1966	Carbon starvation protein
SGR_RS11335	COG0242	peptide deformylase activity
SGR_RS11345	COG5662	AntiSigma factor
SGR_RS11350	COG1595	DNA-templated transcription, initiation
SGR_RS11360	COG2135	peptidase activity
SGR_RS11370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGR_RS11375	COG1162	GTPase activity
SGR_RS11380	COG2076	Multidrug Resistance protein
SGR_RS11390	COG0483	inositol monophosphate 1-phosphatase activity
SGR_RS11400	COG0753	catalase activity
SGR_RS11425	COG1615	UPF0182 protein
SGR_RS11435	COG3480	Lon protease (S16) C-terminal proteolytic domain
SGR_RS11485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SGR_RS11530	COG0210	DNA helicase
SGR_RS11625	COG0513	Belongs to the DEAD box helicase family
SGR_RS11635	COG1432	Conserved Protein
SGR_RS11640	COG2095	MarC family integral membrane protein
SGR_RS11655	COG2814	Major facilitator Superfamily
SGR_RS11665	COG0598	Magnesium transport protein CorA
SGR_RS11700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SGR_RS11705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGR_RS11715	COG1595	DNA-templated transcription, initiation
SGR_RS11725	COG1024	Enoyl-CoA hydratase
SGR_RS11730	COG0519	Catalyzes the synthesis of GMP from XMP
SGR_RS11740	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SGR_RS11745	COG1611	Belongs to the LOG family
SGR_RS11750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGR_RS11780	COG2912	Transglutaminase-like superfamily
SGR_RS11785	COG2197	response regulator
SGR_RS11790	COG1132	(ABC) transporter
SGR_RS11795	COG1132	(ABC) transporter
SGR_RS11805	COG0515	serine threonine protein kinase
SGR_RS11820	COG0110	maltose O-acetyltransferase activity
SGR_RS11845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SGR_RS11865	COG4608	Belongs to the ABC transporter superfamily
SGR_RS11875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS11880	COG0601	transmembrane transport
SGR_RS11885	COG4166	transmembrane transport
SGR_RS11890	COG4608	Belongs to the ABC transporter superfamily
SGR_RS11895	COG0444	Belongs to the ABC transporter superfamily
SGR_RS11900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS11905	COG0601	transmembrane transport
SGR_RS11910	COG4166	transmembrane transport
SGR_RS11915	COG1217	gtp-binding protein TYPA
SGR_RS11925	COG1609	Transcriptional regulator
SGR_RS11940	COG1175	transmembrane transport
SGR_RS11945	COG0395	ABC-type sugar transport system, permease component
SGR_RS11980	COG0456	acetyltransferase
SGR_RS12015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGR_RS12025	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS12065	COG0463	Glycosyl transferase, family 2
SGR_RS12075	COG1842	Phage shock protein A
SGR_RS12160	COG0012	GTP binding
SGR_RS12175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SGR_RS12185	COG1570	exodeoxyribonuclease VII activity
SGR_RS12190	COG1722	exodeoxyribonuclease VII activity
SGR_RS12195	COG0778	Nitroreductase
SGR_RS12220	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SGR_RS12220	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SGR_RS12235	COG3321	synthase
SGR_RS12235	COG0604	alcohol dehydrogenase
SGR_RS12245	COG1362	aminopeptidase activity
SGR_RS12260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGR_RS12270	COG0114	fumarate hydratase activity
SGR_RS12285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGR_RS12285	COG4499	WXG100 protein secretion system (Wss), protein YukC
SGR_RS12305	COG1136	(ABC) transporter
SGR_RS12320	COG0450	alkyl hydroperoxide reductase
SGR_RS12325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGR_RS12340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SGR_RS12345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGR_RS12350	COG0667	Aldo Keto reductase
SGR_RS12400	COG0154	amidase activity
SGR_RS12420	COG2885	chlorophyll binding
SGR_RS12440	COG2197	response regulator
SGR_RS12445	COG3920	Histidine kinase
SGR_RS12475	COG2894	cell division
SGR_RS12505	COG1131	(ABC) transporter
SGR_RS12510	COG1725	Transcriptional regulator
SGR_RS12530	COG2610	gluconate transmembrane transporter activity
SGR_RS12535	COG0251	oxidation-reduction process
SGR_RS12540	COG1414	Transcriptional regulator
SGR_RS12555	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SGR_RS12575	COG1733	regulation of RNA biosynthetic process
SGR_RS12600	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SGR_RS12610	COG1331	Highly conserved protein containing a thioredoxin domain
SGR_RS12630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SGR_RS12640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SGR_RS12660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SGR_RS12670	COG1366	Belongs to the anti-sigma-factor antagonist family
SGR_RS12675	COG1366	Belongs to the anti-sigma-factor antagonist family
SGR_RS12680	COG2172	sigma factor antagonist activity
SGR_RS12690	COG2205	protein histidine kinase activity
SGR_RS12690	COG2202	Pas domain
SGR_RS12700	COG1595	DNA-templated transcription, initiation
SGR_RS12730	COG0583	DNA-binding transcription factor activity
SGR_RS12735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SGR_RS12775	COG2423	ornithine cyclodeaminase activity
SGR_RS12790	COG0475	glutathione-regulated potassium exporter activity
SGR_RS12800	COG1131	(ABC) transporter
SGR_RS12810	COG1335	isochorismatase
SGR_RS12835	COG1396	sequence-specific DNA binding
SGR_RS12840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SGR_RS12860	COG1376	ErfK ybiS ycfS ynhG family protein
SGR_RS12885	COG1024	Enoyl-CoA hydratase
SGR_RS12900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGR_RS12910	COG0424	maF-like protein
SGR_RS12920	COG4770	biotin carboxylase activity
SGR_RS12950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGR_RS12965	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS12970	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS12985	COG1595	DNA-templated transcription, initiation
SGR_RS12990	COG0745	RESPONSE REGULATOR receiver
SGR_RS12995	COG2205	protein histidine kinase activity
SGR_RS13020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGR_RS13030	COG0583	DNA-binding transcription factor activity
SGR_RS13035	COG2814	Major facilitator Superfamily
SGR_RS13055	COG1404	Belongs to the peptidase S8 family
SGR_RS13070	COG1079	Belongs to the binding-protein-dependent transport system permease family
SGR_RS13075	COG4603	Belongs to the binding-protein-dependent transport system permease family
SGR_RS13080	COG3845	ABC transporter
SGR_RS13085	COG1744	ABC transporter substrate-binding protein PnrA-like
SGR_RS13090	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SGR_RS13090	COG1473	amidohydrolase
SGR_RS13110	COG2089	acid synthase
SGR_RS13115	COG1083	cytidylyl-transferase
SGR_RS13125	COG1216	Glycosyl transferase, family 2
SGR_RS13155	COG1216	Glycosyl transferase, family 2
SGR_RS13180	COG1595	DNA-templated transcription, initiation
SGR_RS13185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGR_RS13195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SGR_RS13200	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SGR_RS13205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SGR_RS13210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SGR_RS13255	COG2009	succinate dehydrogenase
SGR_RS13265	COG1053	succinate dehydrogenase
SGR_RS13270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SGR_RS13300	COG1408	metallophosphoesterase
SGR_RS13315	COG1295	ribonuclease BN
SGR_RS13335	COG0180	Tryptophanyl-tRNA synthetase
SGR_RS13340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGR_RS13345	COG0754	glutathionylspermidine amidase activity
SGR_RS13355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGR_RS13360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGR_RS13380	COG0039	L-malate dehydrogenase activity
SGR_RS13395	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SGR_RS13410	COG0138	bifunctional purine biosynthesis protein purh
SGR_RS13440	COG0045	succinate-CoA ligase (ADP-forming) activity
SGR_RS13445	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SGR_RS13455	COG0714	Associated with various cellular activities
SGR_RS13475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SGR_RS13485	COG0739	heme binding
SGR_RS13515	COG2197	response regulator
SGR_RS13550	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SGR_RS13555	COG0519	Catalyzes the synthesis of GMP from XMP
SGR_RS13555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGR_RS13575	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS13580	COG0515	serine threonine protein kinase
SGR_RS13610	COG0516	GMP reductase activity
SGR_RS13620	COG1595	DNA-templated transcription, initiation
SGR_RS13625	COG2197	response regulator
SGR_RS13635	COG0583	DNA-binding transcription factor activity
SGR_RS13645	COG4221	oxidoreductase activity
SGR_RS13650	COG1609	Transcriptional regulator
SGR_RS13665	COG0395	ABC-type sugar transport system, permease component
SGR_RS13680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SGR_RS13690	COG0726	polysaccharide deacetylase
SGR_RS13725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SGR_RS13750	COG0802	atpase or kinase
SGR_RS13760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SGR_RS13765	COG3189	MarR family transcriptional regulator
SGR_RS13775	COG0736	holo-[acyl-carrier-protein] synthase activity
SGR_RS13780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGR_RS13790	COG4941	Belongs to the sigma-70 factor family
SGR_RS13795	COG3795	YCII-related domain
SGR_RS13815	COG1072	(Pantothenic acid kinase))
SGR_RS13825	COG2770	Histidine kinase
SGR_RS13825	COG2208	phosphoserine phosphatase activity
SGR_RS13830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGR_RS13835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SGR_RS13840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SGR_RS13845	COG0488	(ABC) transporter
SGR_RS13855	COG0101	tRNA pseudouridine synthase activity
SGR_RS13860	COG0203	ribosomal protein L17
SGR_RS13865	COG0202	RNA polymerase activity
SGR_RS13870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SGR_RS13875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SGR_RS13880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SGR_RS13885	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SGR_RS13895	COG0563	adenylate kinase activity
SGR_RS13905	COG0200	Binds to the 23S rRNA
SGR_RS13910	COG1841	ribosomal large subunit assembly
SGR_RS13915	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SGR_RS13920	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SGR_RS13925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SGR_RS13930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SGR_RS13935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SGR_RS13940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SGR_RS13945	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SGR_RS13950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SGR_RS13955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SGR_RS13960	COG0255	Belongs to the universal ribosomal protein uL29 family
SGR_RS13965	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SGR_RS13970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SGR_RS13975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SGR_RS13980	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SGR_RS13985	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SGR_RS13990	COG0089	rRNA binding
SGR_RS13995	COG0088	Forms part of the polypeptide exit tunnel
SGR_RS14000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SGR_RS14005	COG0051	transcription antitermination factor activity, RNA binding
SGR_RS14020	COG2197	response regulator
SGR_RS14040	COG4585	Histidine kinase
SGR_RS14045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGR_RS14050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGR_RS14055	COG0049	tRNA binding
SGR_RS14060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SGR_RS14170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SGR_RS14175	COG0085	RNA polymerase activity
SGR_RS14180	COG0222	ribosome binding
SGR_RS14185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SGR_RS14195	COG0081	regulation of translation
SGR_RS14200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SGR_RS14220	COG0436	Aminotransferase
SGR_RS14225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGR_RS14240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SGR_RS14250	COG2030	dehydratase
SGR_RS14255	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SGR_RS14275	COG0702	epimerase
SGR_RS14355	COG0270	DNA (cytosine-5-)-methyltransferase activity
SGR_RS14390	COG1666	GTP binding
SGR_RS14395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGR_RS14410	COG3304	Inner membrane component domain
SGR_RS14415	COG0501	Belongs to the peptidase M48B family
SGR_RS14425	COG1007	ATP synthesis coupled electron transport
SGR_RS14440	COG0713	ATP synthesis coupled electron transport
SGR_RS14445	COG0839	Belongs to the complex I subunit 6 family
SGR_RS14450	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGR_RS14455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SGR_RS14460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGR_RS14465	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGR_RS14470	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGR_RS14490	COG0674	pyruvate-flavodoxin oxidoreductase activity
SGR_RS14490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SGR_RS14495	COG1013	pyruvate-flavodoxin oxidoreductase activity
SGR_RS14500	COG1733	regulation of RNA biosynthetic process
SGR_RS14505	COG0702	epimerase
SGR_RS14585	COG1136	(ABC) transporter
SGR_RS14615	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SGR_RS14620	COG0561	phosphatase activity
SGR_RS14655	COG1131	(ABC) transporter
SGR_RS14665	COG0142	geranyltranstransferase activity
SGR_RS14670	COG3104	oligopeptide transport
SGR_RS14680	COG0179	Fumarylacetoacetate (FAA) hydrolase
SGR_RS14695	COG0514	ATP-dependent DNA helicase (RecQ)
SGR_RS14700	COG1007	ATP synthesis coupled electron transport
SGR_RS14710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGR_RS14715	COG0713	ATP synthesis coupled electron transport
SGR_RS14720	COG0839	Belongs to the complex I subunit 6 family
SGR_RS14725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGR_RS14730	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SGR_RS14735	COG1034	ATP synthesis coupled electron transport
SGR_RS14740	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SGR_RS14750	COG0649	NAD binding
SGR_RS14755	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGR_RS14760	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGR_RS14790	COG2226	methyltransferase
SGR_RS14795	COG2175	clavaminate synthase activity
SGR_RS14805	COG4521	taurine ABC transporter
SGR_RS14810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGR_RS14835	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGR_RS14845	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SGR_RS14850	COG1278	Cold shock
SGR_RS14855	COG4608	Belongs to the ABC transporter superfamily
SGR_RS14865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGR_RS14870	COG0601	transmembrane transport
SGR_RS14875	COG4166	transmembrane transport
SGR_RS14920	COG1024	Enoyl-CoA hydratase
SGR_RS14945	COG1309	transcriptional regulator
SGR_RS14955	COG1960	acyl-CoA dehydrogenase activity
SGR_RS14970	COG0501	Belongs to the peptidase M48B family
SGR_RS14990	COG2072	flavoprotein involved in K transport
SGR_RS14995	COG0477	Major facilitator Superfamily
SGR_RS15040	COG1024	Enoyl-CoA hydratase
SGR_RS15050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGR_RS15055	COG2814	Major facilitator Superfamily
SGR_RS15090	COG1960	acyl-CoA dehydrogenase activity
SGR_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS15110	COG1960	acyl-CoA dehydrogenase activity
SGR_RS15115	COG1960	acyl-CoA dehydrogenase activity
SGR_RS15125	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS15135	COG1366	Belongs to the anti-sigma-factor antagonist family
SGR_RS15185	COG1131	(ABC) transporter
SGR_RS15195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SGR_RS15205	COG4821	SIS domain
SGR_RS15215	COG0259	pyridoxamine-phosphate oxidase activity
SGR_RS15240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SGR_RS15250	COG2318	DinB family
SGR_RS15265	COG0456	acetyltransferase
SGR_RS15285	COG1024	Enoyl-CoA hydratase
SGR_RS15290	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS15305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGR_RS15320	COG1051	belongs to the nudix hydrolase family
SGR_RS15325	COG1309	transcriptional regulator
SGR_RS15335	COG5006	permease, DMT superfamily
SGR_RS15340	COG0583	DNA-binding transcription factor activity
SGR_RS15345	COG0247	lactate metabolic process
SGR_RS15345	COG0277	FAD linked oxidase domain protein
SGR_RS15350	COG2205	protein histidine kinase activity
SGR_RS15380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SGR_RS15390	COG1302	Protein conserved in bacteria
SGR_RS15400	COG1335	isochorismatase
SGR_RS15470	COG1309	transcriptional regulator
SGR_RS15480	COG2205	protein histidine kinase activity
SGR_RS15485	COG0745	RESPONSE REGULATOR receiver
SGR_RS15500	COG1136	(ABC) transporter
SGR_RS15500	COG0577	efflux transmembrane transporter activity
SGR_RS15505	COG0577	efflux transmembrane transporter activity
SGR_RS15505	COG1136	(ABC) transporter
SGR_RS15545	COG1511	domain protein
SGR_RS15580	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS15590	COG0477	Major facilitator Superfamily
SGR_RS15605	COG2267	carboxylic ester hydrolase activity
SGR_RS15620	COG0671	phosphoesterase, PA-phosphatase related
SGR_RS15635	COG0667	Aldo Keto reductase
SGR_RS15660	COG2252	PERMEase
SGR_RS15670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGR_RS15695	COG2814	Major facilitator Superfamily
SGR_RS15705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SGR_RS15710	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SGR_RS15715	COG1278	Cold shock
SGR_RS15730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS15735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS15740	COG1120	ATPase activity
SGR_RS15745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGR_RS15765	COG1061	Type III restriction enzyme res subunit
SGR_RS15775	COG3973	AAA domain
SGR_RS15800	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SGR_RS15830	COG1737	Transcriptional regulator
SGR_RS15835	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SGR_RS15860	COG2201	protein-glutamate methylesterase activity
SGR_RS15865	COG4251	negative regulation of phosphorylation
SGR_RS15900	COG1175	transmembrane transport
SGR_RS15905	COG0395	ABC-type sugar transport system, permease component
SGR_RS15950	COG1595	DNA-templated transcription, initiation
SGR_RS15955	COG1132	(ABC) transporter
SGR_RS15980	COG0463	Glycosyl transferase, family 2
SGR_RS15985	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SGR_RS16010	COG2197	response regulator
SGR_RS16015	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SGR_RS16045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SGR_RS16065	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS16070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SGR_RS16075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SGR_RS16100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGR_RS16105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGR_RS16110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGR_RS16165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGR_RS16185	COG2197	response regulator
SGR_RS16200	COG1136	(ABC) transporter
SGR_RS16200	COG0577	efflux transmembrane transporter activity
SGR_RS16205	COG2124	cytochrome p450
SGR_RS16210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SGR_RS16220	COG3629	intracellular signal transduction
SGR_RS16220	COG3903	Transcriptional regulator
SGR_RS16225	COG3903	Transcriptional regulator
SGR_RS16225	COG3629	intracellular signal transduction
SGR_RS16235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGR_RS16245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SGR_RS16260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGR_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS16260	COG3321	synthase
SGR_RS16260	COG0300	oxidoreductase activity
SGR_RS16260	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS16280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SGR_RS16285	COG0142	geranyltranstransferase activity
SGR_RS16300	COG2197	response regulator
SGR_RS16315	COG4585	Histidine kinase
SGR_RS16330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SGR_RS16335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SGR_RS16340	COG1754	DNA topoisomerase type I activity
SGR_RS16340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SGR_RS16350	COG2890	protein-(glutamine-N5) methyltransferase activity
SGR_RS16360	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SGR_RS16365	COG2172	sigma factor antagonist activity
SGR_RS16370	COG1366	Belongs to the anti-sigma-factor antagonist family
SGR_RS16375	COG1111	helicase
SGR_RS16375	COG1205	dead DEAH box helicase
SGR_RS16470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SGR_RS16475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SGR_RS16485	COG2267	carboxylic ester hydrolase activity
SGR_RS16510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGR_RS16520	COG0251	oxidation-reduction process
SGR_RS16530	COG0003	Pfam Anion-transporting ATPase
SGR_RS16540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SGR_RS16545	COG1610	YqeY-like protein
SGR_RS16550	COG1408	metallophosphoesterase
SGR_RS16650	COG2755	lipolytic protein G-D-S-L family
SGR_RS16660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SGR_RS16680	COG1595	DNA-templated transcription, initiation
SGR_RS16705	COG0702	epimerase
SGR_RS16715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SGR_RS16720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SGR_RS16735	COG1802	Transcriptional regulator
SGR_RS16740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SGR_RS16745	COG0693	protein deglycase activity
SGR_RS16755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SGR_RS16755	COG0515	serine threonine protein kinase
SGR_RS16760	COG0738	Major facilitator superfamily
SGR_RS16765	COG3226	Transcriptional regulator
SGR_RS16820	COG0592	DNA-directed DNA polymerase activity
SGR_RS16825	COG2319	Wd-40 repeat
SGR_RS16825	COG4249	Peptidase C14 caspase catalytic subunit p20
SGR_RS16855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SGR_RS16880	COG2197	response regulator
SGR_RS16885	COG4585	Histidine kinase
SGR_RS16890	COG0702	epimerase
SGR_RS16900	COG3844	kynureninase activity
SGR_RS16915	COG0477	Major facilitator Superfamily
SGR_RS16920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SGR_RS16925	COG0191	fructose-bisphosphate aldolase activity
SGR_RS16930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SGR_RS16945	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SGR_RS16970	COG0542	response to heat
SGR_RS17000	COG0789	Transcriptional regulator
SGR_RS17005	COG0484	heat shock protein binding
SGR_RS17010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SGR_RS17015	COG0443	Heat shock 70 kDa protein
SGR_RS17020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGR_RS17025	COG0247	lactate metabolic process
SGR_RS17025	COG2181	nitrate reductase activity
SGR_RS17045	COG0717	Belongs to the dCTP deaminase family
SGR_RS17100	COG3209	COG3209 Rhs family protein
SGR_RS17140	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SGR_RS17170	COG2205	protein histidine kinase activity
SGR_RS17175	COG0745	RESPONSE REGULATOR receiver
SGR_RS17205	COG0745	RESPONSE REGULATOR receiver
SGR_RS17215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGR_RS17225	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SGR_RS17230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SGR_RS17240	COG0519	Catalyzes the synthesis of GMP from XMP
SGR_RS17240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGR_RS17245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SGR_RS17250	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS17265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS17270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS17280	COG1609	Transcriptional regulator
SGR_RS17305	COG2124	cytochrome p450
SGR_RS17330	COG3585	molybdate ion transport
SGR_RS17355	COG0531	amino acid
SGR_RS17365	COG0475	glutathione-regulated potassium exporter activity
SGR_RS17370	COG2409	Drug exporters of the RND superfamily
SGR_RS17375	COG3594	Acyltransferase
SGR_RS17390	COG0513	Belongs to the DEAD box helicase family
SGR_RS17395	COG1278	Cold shock
SGR_RS17450	COG0450	alkyl hydroperoxide reductase
SGR_RS17460	COG2268	Band 7 protein
SGR_RS17485	COG4941	Belongs to the sigma-70 factor family
SGR_RS17510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SGR_RS17540	COG2154	pterin-4-alpha-carbinolamine dehydratase
SGR_RS17575	COG1518	maintenance of DNA repeat elements
SGR_RS17590	COG1191	sigma factor activity
SGR_RS17595	COG1191	sigma factor activity
SGR_RS17620	COG2353	YceI-like domain
SGR_RS17625	COG3467	pyridoxamine 5'-phosphate
SGR_RS17640	COG0477	Major facilitator Superfamily
SGR_RS17655	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SGR_RS17665	COG2205	protein histidine kinase activity
SGR_RS17670	COG0745	RESPONSE REGULATOR receiver
SGR_RS17690	COG1595	DNA-templated transcription, initiation
SGR_RS17715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SGR_RS17740	COG0758	DNA mediated transformation
SGR_RS17830	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS17835	COG1595	DNA-templated transcription, initiation
SGR_RS17860	COG1960	acyl-CoA dehydrogenase activity
SGR_RS17895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGR_RS17910	COG0653	protein targeting
SGR_RS17930	COG0006	proline dipeptidase activity
SGR_RS17950	COG1999	signal sequence binding
SGR_RS17960	COG2372	response to copper ion
SGR_RS17965	COG2837	iron assimilation
SGR_RS17975	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SGR_RS17980	COG0561	phosphatase activity
SGR_RS18005	COG1131	(ABC) transporter
SGR_RS18025	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SGR_RS18035	COG0561	phosphatase activity
SGR_RS18045	COG4988	ABC transporter
SGR_RS18050	COG1294	oxidase, subunit
SGR_RS18055	COG1271	oxidase subunit
SGR_RS18060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGR_RS18065	COG1609	Transcriptional regulator
SGR_RS18080	COG3152	Membrane
SGR_RS18090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SGR_RS18115	COG0662	Cupin 2, conserved barrel domain protein
SGR_RS18120	COG1950	PFAM Membrane protein of
SGR_RS18125	COG0626	cystathionine gamma-synthase activity
SGR_RS18140	COG2814	Major facilitator Superfamily
SGR_RS18160	COG0137	argininosuccinate synthase activity
SGR_RS18165	COG0305	Participates in initiation and elongation during chromosome replication
SGR_RS18175	COG0359	binds to the 23S rRNA
SGR_RS18180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGR_RS18185	COG0629	single-stranded DNA binding
SGR_RS18190	COG0360	Binds together with S18 to 16S ribosomal RNA
SGR_RS18215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGR_RS18240	COG0617	tRNA 3'-terminal CCA addition
SGR_RS18255	COG0515	serine threonine protein kinase
SGR_RS18255	COG2815	serine threonine protein kinase
SGR_RS18260	COG1595	DNA-templated transcription, initiation
SGR_RS18270	COG0492	ferredoxin-NADP+ reductase activity
SGR_RS18275	COG3118	belongs to the thioredoxin family
SGR_RS18290	COG1192	Involved in chromosome partitioning
SGR_RS18295	COG0357	Ribosomal RNA small subunit methyltransferase G
SGR_RS18305	COG0706	membrane insertase activity
SGR_RS18310	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SGR_RS18315	COG0592	DNA-directed DNA polymerase activity
SGR_RS18320	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SGR_RS18325	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGR_RS18330	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SGR_RS18340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGR_RS18370	COG0515	serine threonine protein kinase
SGR_RS18400	COG0705	Rhomboid family
SGR_RS18415	COG3764	Sortase (surface protein transpeptidase)
SGR_RS18430	COG3764	Sortase (surface protein transpeptidase)
SGR_RS18435	COG3764	Sortase (surface protein transpeptidase)
SGR_RS18440	COG0515	serine threonine protein kinase
SGR_RS18445	COG0768	penicillin binding
SGR_RS18460	COG1716	ATPase activity
SGR_RS18465	COG1716	ATPase activity
SGR_RS18480	COG1733	regulation of RNA biosynthetic process
SGR_RS18505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SGR_RS18510	COG2151	metal-sulfur cluster biosynthetic enzyme
SGR_RS18515	COG3396	Phenylacetate-CoA oxygenase
SGR_RS18520	COG3460	Phenylacetate-CoA oxygenase
SGR_RS18525	COG3396	Phenylacetate-CoA oxygenase
SGR_RS18550	COG1309	transcriptional regulator
SGR_RS18555	COG1522	sequence-specific DNA binding
SGR_RS18590	COG0604	alcohol dehydrogenase
SGR_RS18605	COG4591	ABC-type transport system involved in lipoprotein release permease component
SGR_RS18605	COG1136	(ABC) transporter
SGR_RS18620	COG0515	serine threonine protein kinase
SGR_RS18625	COG0515	serine threonine protein kinase
SGR_RS18650	COG0022	dehydrogenase e1 component
SGR_RS18655	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGR_RS18680	COG1802	Transcriptional regulator
SGR_RS18695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGR_RS18720	COG3903	Transcriptional regulator
SGR_RS18720	COG3629	intracellular signal transduction
SGR_RS18730	COG1362	aminopeptidase activity
SGR_RS18735	COG1960	acyl-CoA dehydrogenase activity
SGR_RS18745	COG1741	Belongs to the pirin family
SGR_RS18760	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SGR_RS18770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGR_RS18775	COG0745	RESPONSE REGULATOR receiver
SGR_RS18780	COG2205	protein histidine kinase activity
SGR_RS18785	COG2304	oxidoreductase activity
SGR_RS18815	COG0431	NADPH-dependent FMN reductase
SGR_RS18835	COG1672	PFAM Archaeal ATPase
SGR_RS18835	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SGR_RS18850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS18855	COG0180	Tryptophanyl-tRNA synthetase
SGR_RS18865	COG2255	four-way junction helicase activity
SGR_RS18890	COG0475	glutathione-regulated potassium exporter activity
SGR_RS18895	COG0490	domain, Protein
SGR_RS18910	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SGR_RS19045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SGR_RS19090	COG0151	Belongs to the GarS family
SGR_RS19105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SGR_RS19115	COG2197	response regulator
SGR_RS19130	COG1131	(ABC) transporter
SGR_RS19150	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGR_RS19155	COG0047	phosphoribosylformylglycinamidine synthase activity
SGR_RS19160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGR_RS19170	COG0739	heme binding
SGR_RS19170	COG0741	lytic transglycosylase activity
SGR_RS19170	COG1196	nuclear chromosome segregation
SGR_RS19185	COG3119	arylsulfatase activity
SGR_RS19195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SGR_RS19230	COG1643	Atp-dependent helicase
SGR_RS19240	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SGR_RS19240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SGR_RS19245	COG0785	Cytochrome C biogenesis protein
SGR_RS19275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SGR_RS19280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SGR_RS19290	COG0513	Belongs to the DEAD box helicase family
SGR_RS19315	COG0789	Transcriptional regulator
SGR_RS19325	COG0739	heme binding
SGR_RS19325	COG0741	lytic transglycosylase activity
SGR_RS19325	COG1196	nuclear chromosome segregation
SGR_RS19340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SGR_RS19345	COG0579	oxidoreductase
SGR_RS19370	COG1252	NADH dehydrogenase
SGR_RS19385	COG1846	Transcriptional regulator
SGR_RS19405	COG2197	response regulator
SGR_RS19410	COG4585	Histidine kinase
SGR_RS19420	COG1131	(ABC) transporter
SGR_RS19470	COG1196	nuclear chromosome segregation
SGR_RS19470	COG0739	heme binding
SGR_RS19470	COG0741	lytic transglycosylase activity
SGR_RS19475	COG0671	phosphoesterase, PA-phosphatase related
SGR_RS19495	COG1937	Protein conserved in bacteria
SGR_RS19505	COG0306	phosphate transporter
SGR_RS19525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SGR_RS19530	COG0406	alpha-ribazole phosphatase activity
SGR_RS19530	COG0494	nUDIX hydrolase
SGR_RS19555	COG1725	Transcriptional regulator
SGR_RS19560	COG0456	acetyltransferase
SGR_RS19565	COG0737	Belongs to the 5'-nucleotidase family
SGR_RS19610	COG0739	heme binding
SGR_RS19645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGR_RS19650	COG1609	Transcriptional regulator
SGR_RS19655	COG0745	RESPONSE REGULATOR receiver
SGR_RS19680	COG2897	thiosulfate sulfurtransferase activity
SGR_RS19705	COG3485	protocatechuate 3,4-dioxygenase
SGR_RS19720	COG1490	D-aminoacyl-tRNA deacylase activity
SGR_RS19735	COG4552	Acetyltransferase involved in intracellular survival and related
SGR_RS19815	COG0438	transferase activity, transferring glycosyl groups
SGR_RS19870	COG0588	phosphoglycerate mutase activity
SGR_RS19885	COG5002	protein histidine kinase activity
SGR_RS19900	COG1329	Transcriptional regulator
SGR_RS19905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SGR_RS19910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SGR_RS19920	COG0747	negative chemotaxis
SGR_RS19935	COG3467	pyridoxamine 5'-phosphate
SGR_RS19940	COG0215	cysteine-tRNA ligase activity
SGR_RS19945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGR_RS19965	COG3842	ATPase activity
SGR_RS20025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGR_RS20040	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SGR_RS20060	COG2197	response regulator
SGR_RS20065	COG4585	Histidine kinase
SGR_RS20075	COG0666	response to abiotic stimulus
SGR_RS20100	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SGR_RS20120	COG1105	Belongs to the carbohydrate kinase PfkB family
SGR_RS20125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SGR_RS20160	COG1595	DNA-templated transcription, initiation
SGR_RS20170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGR_RS20170	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGR_RS20205	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS20235	COG0076	glutamate decarboxylase activity
SGR_RS20240	COG0655	NAD(P)H dehydrogenase (quinone) activity
SGR_RS20250	COG0393	Putative heavy-metal-binding
SGR_RS20255	COG0586	Pfam SNARE associated Golgi protein
SGR_RS20265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SGR_RS20270	COG2027	D-alanyl-D-alanine carboxypeptidase
SGR_RS20280	COG0037	tRNA processing
SGR_RS20295	COG0302	gtp cyclohydrolase
SGR_RS20305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SGR_RS20310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SGR_RS20325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SGR_RS20325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SGR_RS20335	COG0517	IMP dehydrogenase activity
SGR_RS20335	COG1125	glycine betaine transport
SGR_RS20340	COG1174	glycine betaine transport
SGR_RS20345	COG1174	glycine betaine transport
SGR_RS20350	COG1732	Glycine betaine
SGR_RS20360	COG0649	NAD binding
SGR_RS20375	COG2197	response regulator
SGR_RS20395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SGR_RS20400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SGR_RS20410	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SGR_RS20430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SGR_RS20460	COG0739	heme binding
SGR_RS20465	COG2205	protein histidine kinase activity
SGR_RS20470	COG0745	RESPONSE REGULATOR receiver
SGR_RS20480	COG1595	DNA-templated transcription, initiation
SGR_RS20485	COG1194	a g-specific adenine glycosylase
SGR_RS20495	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SGR_RS20515	COG0248	Ppx GppA phosphatase
SGR_RS20520	COG1082	Xylose isomerase domain protein TIM barrel
SGR_RS20530	COG0129	dihydroxy-acid dehydratase activity
SGR_RS20535	COG0515	serine threonine protein kinase
SGR_RS20535	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SGR_RS20540	COG4991	sh3 domain protein
SGR_RS20550	COG0842	Transport permease protein
SGR_RS20550	COG1129	ABC transporter
SGR_RS20560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SGR_RS20580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGR_RS20635	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SGR_RS20640	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SGR_RS20645	COG0181	hydroxymethylbilane synthase activity
SGR_RS20650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SGR_RS20650	COG1648	precorrin-2 dehydrogenase activity
SGR_RS20655	COG0113	porphobilinogen synthase activity
SGR_RS20695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGR_RS20710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SGR_RS20735	COG1802	Transcriptional regulator
SGR_RS20755	COG0018	arginyl-trna synthetase
SGR_RS20760	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SGR_RS20785	COG1690	Belongs to the RtcB family
SGR_RS20820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SGR_RS20825	COG0406	alpha-ribazole phosphatase activity
SGR_RS20845	COG0785	Cytochrome C biogenesis protein
SGR_RS20850	COG1333	cytochrome c biogenesis protein
SGR_RS20855	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SGR_RS20865	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SGR_RS20870	COG0109	protoheme IX farnesyltransferase activity
SGR_RS20875	COG0705	Rhomboid family
SGR_RS20880	COG0163	prenyltransferase activity
SGR_RS20890	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGR_RS20905	COG1301	dicarboxylic acid transport
SGR_RS20915	COG1309	transcriptional regulator
SGR_RS20930	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS21020	COG0768	penicillin binding
SGR_RS21035	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGR_RS21040	COG0667	Aldo Keto reductase
SGR_RS21060	COG3903	Transcriptional regulator
SGR_RS21060	COG3629	intracellular signal transduction
SGR_RS21090	COG2304	oxidoreductase activity
SGR_RS21095	COG2814	Major facilitator Superfamily
SGR_RS21130	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS21225	COG1846	Transcriptional regulator
SGR_RS21230	COG3384	dioxygenase
SGR_RS21250	COG0477	Major facilitator Superfamily
SGR_RS21260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGR_RS21265	COG0640	Transcriptional regulator
SGR_RS21280	COG0243	molybdopterin cofactor binding
SGR_RS21285	COG0437	4 iron, 4 sulfur cluster binding
SGR_RS21310	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SGR_RS21340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SGR_RS21345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SGR_RS21355	COG0315	cyclic pyranopterin monophosphate synthase activity
SGR_RS21360	COG0521	Mo-molybdopterin cofactor biosynthetic process
SGR_RS21420	COG0708	Exodeoxyribonuclease III
SGR_RS21430	COG2072	flavoprotein involved in K transport
SGR_RS21435	COG2267	carboxylic ester hydrolase activity
SGR_RS21440	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS21450	COG4946	Tricorn protease homolog
SGR_RS21450	COG0793	Belongs to the peptidase S41A family
SGR_RS21460	COG2409	Drug exporters of the RND superfamily
SGR_RS21475	COG0310	cobalt ion transport
SGR_RS21485	COG1122	ATPase activity
SGR_RS21490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGR_RS21495	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS21505	COG2364	Membrane
SGR_RS21510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGR_RS21550	COG0442	prolyl-tRNA aminoacylation
SGR_RS21555	COG2207	Transcriptional regulator
SGR_RS21560	COG2223	nitrite transmembrane transporter activity
SGR_RS21605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGR_RS21630	COG0084	hydrolase, TatD family'
SGR_RS21640	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SGR_RS21645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SGR_RS21670	COG0488	(ABC) transporter
SGR_RS21700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGR_RS21715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SGR_RS21725	COG2197	response regulator
SGR_RS21730	COG1846	Transcriptional regulator
SGR_RS21735	COG4106	trans-aconitate 2-methyltransferase activity
SGR_RS21755	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SGR_RS21765	COG0193	aminoacyl-tRNA hydrolase activity
SGR_RS21770	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SGR_RS21775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SGR_RS21780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SGR_RS21785	COG4585	Histidine kinase
SGR_RS21815	COG2124	cytochrome p450
SGR_RS21820	COG2124	cytochrome p450
SGR_RS21860	COG0346	lactoylglutathione lyase activity
SGR_RS21865	COG0640	Transcriptional regulator
SGR_RS21875	COG2814	Major facilitator Superfamily
SGR_RS21880	COG1136	(ABC) transporter
SGR_RS21885	COG0577	efflux transmembrane transporter activity
SGR_RS21895	COG3629	intracellular signal transduction
SGR_RS21895	COG3903	Transcriptional regulator
SGR_RS21950	COG1473	amidohydrolase
SGR_RS21995	COG1335	isochorismatase
SGR_RS22015	COG2815	serine threonine protein kinase
SGR_RS22015	COG0515	serine threonine protein kinase
SGR_RS22035	COG2124	cytochrome p450
SGR_RS22050	COG0148	phosphopyruvate hydratase activity
SGR_RS22070	COG1252	NADH dehydrogenase
SGR_RS22075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SGR_RS22080	COG0577	efflux transmembrane transporter activity
SGR_RS22080	COG1136	(ABC) transporter
SGR_RS22085	COG0577	efflux transmembrane transporter activity
SGR_RS22085	COG1136	(ABC) transporter
SGR_RS22110	COG0183	Belongs to the thiolase family
SGR_RS22115	COG2755	lipolytic protein G-D-S-L family
SGR_RS22170	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SGR_RS22185	COG1228	amidohydrolase
SGR_RS22190	COG1191	sigma factor activity
SGR_RS22195	COG1366	Belongs to the anti-sigma-factor antagonist family
SGR_RS22225	COG3104	oligopeptide transport
SGR_RS22230	COG0745	RESPONSE REGULATOR receiver
SGR_RS22235	COG2205	protein histidine kinase activity
SGR_RS22265	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SGR_RS22300	COG1316	TRANSCRIPTIONal
SGR_RS22305	COG1607	acyl-coa hydrolase
SGR_RS22310	COG1316	TRANSCRIPTIONal
SGR_RS22325	COG1316	TRANSCRIPTIONal
SGR_RS22330	COG1316	TRANSCRIPTIONal
SGR_RS22345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SGR_RS22355	COG0531	amino acid
SGR_RS22360	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SGR_RS22360	COG0778	Nitroreductase
SGR_RS22365	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SGR_RS22400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGR_RS22405	COG2835	tetraacyldisaccharide 4'-kinase activity
SGR_RS22425	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SGR_RS22465	COG0714	Associated with various cellular activities
SGR_RS22485	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SGR_RS22490	COG0745	RESPONSE REGULATOR receiver
SGR_RS22495	COG5002	protein histidine kinase activity
SGR_RS22495	COG5000	phosphorelay sensor kinase activity
SGR_RS22500	COG0823	Involved in the tonB-independent uptake of proteins
SGR_RS22510	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SGR_RS22515	COG2197	response regulator
SGR_RS22530	COG0653	protein targeting
SGR_RS22555	COG2902	Dehydrogenase
SGR_RS22560	COG1134	teichoic acid transport
SGR_RS22570	COG1309	transcriptional regulator
SGR_RS22580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGR_RS22585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGR_RS22590	COG1073	alpha beta
SGR_RS22590	COG2226	methyltransferase
SGR_RS22595	COG4122	O-methyltransferase activity
SGR_RS22600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGR_RS22605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGR_RS22610	COG0438	transferase activity, transferring glycosyl groups
SGR_RS22615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGR_RS22620	COG0395	ABC-type sugar transport system, permease component
SGR_RS22625	COG1175	transmembrane transport
SGR_RS22630	COG1653	transport
SGR_RS22640	COG0515	serine threonine protein kinase
SGR_RS22645	COG0515	serine threonine protein kinase
SGR_RS22650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SGR_RS22665	COG2884	Cell division ATP-binding protein ftsE
SGR_RS22670	COG2177	Part of the ABC transporter FtsEX involved in
SGR_RS22675	COG0793	Belongs to the peptidase S41A family
SGR_RS22680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SGR_RS22685	COG1132	(ABC) transporter
SGR_RS22690	COG1132	(ABC) transporter
SGR_RS22710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS22715	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS22720	COG1120	ATPase activity
SGR_RS22730	COG0583	DNA-binding transcription factor activity
SGR_RS22750	COG2223	nitrite transmembrane transporter activity
SGR_RS22775	COG3973	AAA domain
SGR_RS22775	COG3973	AAA domain
SGR_RS22785	COG0776	regulation of translation
SGR_RS22800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGR_RS22805	COG1678	Uncharacterized ACR, COG1678
SGR_RS22820	COG1175	transmembrane transport
SGR_RS22825	COG0395	ABC-type sugar transport system, permease component
SGR_RS22830	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SGR_RS22880	COG2814	Major facilitator Superfamily
SGR_RS22895	COG3480	Lon protease (S16) C-terminal proteolytic domain
SGR_RS22915	COG1732	Glycine betaine
SGR_RS22920	COG1174	glycine betaine transport
SGR_RS22925	COG1125	glycine betaine transport
SGR_RS22925	COG0517	IMP dehydrogenase activity
SGR_RS22930	COG1174	glycine betaine transport
SGR_RS22940	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SGR_RS22950	COG0277	FAD linked oxidase domain protein
SGR_RS22985	COG1335	isochorismatase
SGR_RS22995	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SGR_RS23005	COG1113	amino acid transport
SGR_RS23015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGR_RS23020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS23045	COG1234	tRNA 3'-trailer cleavage
SGR_RS23050	COG1263	PTS System
SGR_RS23055	COG1263	PTS System
SGR_RS23060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGR_RS23065	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SGR_RS23075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SGR_RS23095	COG0477	Major facilitator Superfamily
SGR_RS23115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGR_RS23130	COG4555	ABC transporter
SGR_RS23145	COG2733	membrane
SGR_RS23155	COG2267	carboxylic ester hydrolase activity
SGR_RS23230	COG1074	ATP-dependent DNA helicase activity
SGR_RS23260	COG0270	DNA (cytosine-5-)-methyltransferase activity
SGR_RS23280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SGR_RS23290	COG3764	Sortase (surface protein transpeptidase)
SGR_RS23300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGR_RS23310	COG0706	membrane insertase activity
SGR_RS23310	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
SGR_RS23320	COG4702	Belongs to the UPF0303 family
SGR_RS23325	COG0673	inositol 2-dehydrogenase activity
SGR_RS23340	COG2188	Transcriptional regulator
SGR_RS23345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGR_RS23425	COG3397	chitin binding
SGR_RS23430	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS23445	COG1126	abc transporter atp-binding protein
SGR_RS23450	COG0765	amino acid transport
SGR_RS23455	COG0765	amino acid transport
SGR_RS23460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS23475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS23520	COG0588	phosphoglycerate mutase activity
SGR_RS23560	COG2985	domain, Protein
SGR_RS23565	COG2985	domain, Protein
SGR_RS23580	COG0395	ABC-type sugar transport system, permease component
SGR_RS23595	COG3397	chitin binding
SGR_RS23610	COG4977	sequence-specific DNA binding
SGR_RS23620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGR_RS23645	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SGR_RS23650	COG0076	glutamate decarboxylase activity
SGR_RS23655	COG2375	cellular response to nickel ion
SGR_RS23665	COG1733	regulation of RNA biosynthetic process
SGR_RS23680	COG1960	acyl-CoA dehydrogenase activity
SGR_RS23695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SGR_RS23700	COG1309	transcriptional regulator
SGR_RS23720	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SGR_RS23720	COG2755	lipolytic protein G-D-S-L family
SGR_RS23740	COG1946	Acyl-CoA thioesterase
SGR_RS23815	COG4106	trans-aconitate 2-methyltransferase activity
SGR_RS23835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGR_RS23845	COG0028	Belongs to the TPP enzyme family
SGR_RS23875	COG1472	Belongs to the glycosyl hydrolase 3 family
SGR_RS23890	COG1404	Belongs to the peptidase S8 family
SGR_RS23920	COG0515	serine threonine protein kinase
SGR_RS23960	COG0673	inositol 2-dehydrogenase activity
SGR_RS23995	COG0596	Alpha beta hydrolase
SGR_RS24010	COG0477	Major facilitator Superfamily
SGR_RS24020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SGR_RS24045	COG2409	Drug exporters of the RND superfamily
SGR_RS24050	COG2226	methyltransferase
SGR_RS24075	COG3718	enzyme involved in inositol metabolism
SGR_RS24080	COG3962	Belongs to the TPP enzyme family
SGR_RS24095	COG4585	Histidine kinase
SGR_RS24110	COG1131	(ABC) transporter
SGR_RS24155	COG0629	single-stranded DNA binding
SGR_RS24185	COG1136	(ABC) transporter
SGR_RS24185	COG0577	efflux transmembrane transporter activity
SGR_RS24200	COG2346	COG2346, Truncated hemoglobins
SGR_RS24205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SGR_RS24240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS24255	COG1486	melibiose metabolic process
SGR_RS24260	COG0395	ABC-type sugar transport system, permease component
SGR_RS24265	COG1175	transmembrane transport
SGR_RS24280	COG0668	transmembrane transport
SGR_RS24290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SGR_RS24290	COG3291	Pkd domain containing protein
SGR_RS24315	COG4266	Belongs to the allantoicase family
SGR_RS24360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SGR_RS24375	COG2252	PERMEase
SGR_RS24385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SGR_RS24415	COG0110	maltose O-acetyltransferase activity
SGR_RS24430	COG0640	Transcriptional regulator
SGR_RS24435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SGR_RS24440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SGR_RS24450	COG0584	glycerophosphoryl diester phosphodiesterase
SGR_RS24455	COG1113	amino acid transport
SGR_RS24460	COG1113	amino acid transport
SGR_RS24465	COG1268	BioY protein
SGR_RS24475	COG1113	amino acid transport
SGR_RS24495	COG0475	glutathione-regulated potassium exporter activity
SGR_RS24505	COG3594	Acyltransferase
SGR_RS24525	COG0544	peptidyl-prolyl cis-trans isomerase activity
SGR_RS24530	COG0740	serine-type endopeptidase activity
SGR_RS24535	COG0740	serine-type endopeptidase activity
SGR_RS24540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SGR_RS24550	COG0525	valine-tRNA ligase activity
SGR_RS24555	COG0285	dihydrofolate synthase activity
SGR_RS24565	COG0105	UTP biosynthetic process
SGR_RS24570	COG1077	Cell shape determining protein MreB Mrl
SGR_RS24590	COG0772	Belongs to the SEDS family
SGR_RS24615	COG1530	ribonuclease E activity
SGR_RS24620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SGR_RS24625	COG0673	inositol 2-dehydrogenase activity
SGR_RS24675	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SGR_RS24680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SGR_RS24685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SGR_RS24705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SGR_RS24710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SGR_RS24720	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SGR_RS24735	COG0501	Belongs to the peptidase M48B family
SGR_RS24750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SGR_RS24760	COG0799	negative regulation of ribosome biogenesis
SGR_RS24765	COG0588	phosphoglycerate mutase activity
SGR_RS24785	COG0495	leucyl-tRNA aminoacylation
SGR_RS24795	COG1307	EDD domain protein, DegV family
SGR_RS24800	COG1555	photosystem II stabilization
SGR_RS24835	COG0268	Binds directly to 16S ribosomal RNA
SGR_RS24840	COG0481	GTPase activity
SGR_RS24885	COG1420	regulation of RNA biosynthetic process
SGR_RS24890	COG0484	heat shock protein binding
SGR_RS24905	COG0537	adenosine 5'-monophosphoramidase activity
SGR_RS24910	COG1234	tRNA 3'-trailer cleavage
SGR_RS24915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SGR_RS24925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SGR_RS24925	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SGR_RS24935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SGR_RS24945	COG2315	Protein conserved in bacteria
SGR_RS24965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SGR_RS24980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGR_RS24990	COG1381	Involved in DNA repair and RecF pathway recombination
SGR_RS24995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGR_RS25005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGR_RS25010	COG1121	(ABC) transporter
SGR_RS25020	COG0423	glycine-tRNA ligase activity
SGR_RS25070	COG1595	DNA-templated transcription, initiation
SGR_RS25100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGR_RS25115	COG2066	Belongs to the glutaminase family
SGR_RS25125	COG2226	methyltransferase
SGR_RS25135	COG1309	transcriptional regulator
SGR_RS25155	COG0574	Belongs to the PEP-utilizing enzyme family
SGR_RS25155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGR_RS25175	COG2146	nitrite reductase [NAD(P)H] activity
SGR_RS25175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SGR_RS25180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SGR_RS25180	COG2146	nitrite reductase [NAD(P)H] activity
SGR_RS25185	COG0730	response to heat
SGR_RS25225	COG2949	membrane
SGR_RS25235	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SGR_RS25245	COG0358	DNA primase activity
SGR_RS25265	COG1070	Carbohydrate kinase
SGR_RS25330	COG0402	S-adenosylhomocysteine deaminase activity
SGR_RS25340	COG1609	Transcriptional regulator
SGR_RS25345	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS25350	COG1309	transcriptional regulator
SGR_RS25365	COG0825	malonyl-CoA metabolic process
SGR_RS25365	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SGR_RS25370	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS25375	COG3291	Pkd domain containing protein
SGR_RS25390	COG1522	sequence-specific DNA binding
SGR_RS25420	COG2130	NADP-dependent
SGR_RS25425	COG1764	response to oxidative stress
SGR_RS25455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGR_RS25460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGR_RS25465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGR_RS25480	COG1741	Belongs to the pirin family
SGR_RS25495	COG2814	Major facilitator Superfamily
SGR_RS25505	COG1929	Belongs to the glycerate kinase type-1 family
SGR_RS25515	COG0745	RESPONSE REGULATOR receiver
SGR_RS25520	COG2205	protein histidine kinase activity
SGR_RS25530	COG0789	Transcriptional regulator
SGR_RS25535	COG0667	Aldo Keto reductase
SGR_RS25550	COG2197	response regulator
SGR_RS25555	COG4585	Histidine kinase
SGR_RS25570	COG1309	transcriptional regulator
SGR_RS25575	COG0477	Major facilitator Superfamily
SGR_RS25585	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SGR_RS25630	COG1358	cellular component organization or biogenesis
SGR_RS25690	COG0483	inositol monophosphate 1-phosphatase activity
SGR_RS25780	COG2124	cytochrome p450
SGR_RS25785	COG0183	Belongs to the thiolase family
SGR_RS25795	COG3845	ABC transporter
SGR_RS25865	COG1309	transcriptional regulator
SGR_RS25870	COG0438	transferase activity, transferring glycosyl groups
SGR_RS25900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS25920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGR_RS25925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SGR_RS25940	COG3340	Belongs to the peptidase S51 family
SGR_RS25950	COG1960	acyl-CoA dehydrogenase activity
SGR_RS25955	COG0183	Belongs to the thiolase family
SGR_RS25960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SGR_RS25970	COG2030	dehydratase
SGR_RS25980	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS25990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGR_RS25995	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SGR_RS26015	COG0800	Aldolase
SGR_RS26020	COG3022	response to hydroperoxide
SGR_RS26035	COG0456	acetyltransferase
SGR_RS26060	COG0384	phenazine biosynthesis protein PhzF
SGR_RS26070	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS26075	COG3540	Alkaline phosphatase
SGR_RS26085	COG2814	Major facilitator Superfamily
SGR_RS26100	COG1834	amidinotransferase
SGR_RS26120	COG1120	ATPase activity
SGR_RS26125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS26130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGR_RS26150	COG5398	heme oxygenase
SGR_RS26180	COG1994	Peptidase M50
SGR_RS26200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SGR_RS26205	COG0477	Major facilitator Superfamily
SGR_RS26220	COG2814	Major facilitator Superfamily
SGR_RS26225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SGR_RS26225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGR_RS26230	COG2132	Multicopper oxidase
SGR_RS26255	COG0174	glutamine synthetase
SGR_RS26285	COG2814	Major facilitator Superfamily
SGR_RS26290	COG2890	protein-(glutamine-N5) methyltransferase activity
SGR_RS26295	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SGR_RS26305	COG1609	Transcriptional regulator
SGR_RS26310	COG2182	Extracellular solute-binding protein
SGR_RS26320	COG0395	ABC-type sugar transport system, permease component
SGR_RS26325	COG0366	Alpha amylase catalytic
SGR_RS26360	COG3903	Transcriptional regulator
SGR_RS26360	COG3629	intracellular signal transduction
SGR_RS26375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGR_RS26385	COG2130	NADP-dependent
SGR_RS26410	COG0156	8-amino-7-oxononanoate synthase activity
SGR_RS26430	COG2197	response regulator
SGR_RS26435	COG4585	Histidine kinase
SGR_RS26440	COG0745	RESPONSE REGULATOR receiver
SGR_RS26465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGR_RS26470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SGR_RS26490	COG3467	pyridoxamine 5'-phosphate
SGR_RS26495	COG3896	Chloramphenicol phosphotransferase-like protein
SGR_RS26500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGR_RS26525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SGR_RS26530	COG0321	lipoyl(octanoyl) transferase activity
SGR_RS26545	COG1090	epimerase
SGR_RS26565	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SGR_RS26575	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGR_RS26580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGR_RS26585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SGR_RS26590	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SGR_RS26605	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SGR_RS26620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGR_RS26625	COG2226	methyltransferase
SGR_RS26650	COG2197	response regulator
SGR_RS26655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SGR_RS26660	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SGR_RS26680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGR_RS26685	COG1104	cysteine desulfurase activity
SGR_RS26690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SGR_RS26695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SGR_RS26705	COG1376	ErfK ybiS ycfS ynhG family protein
SGR_RS26715	COG1845	cytochrome c oxidase, subunit III
SGR_RS26720	COG2010	Cytochrome c
SGR_RS26725	COG0723	plastoquinol--plastocyanin reductase activity
SGR_RS26730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SGR_RS26735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SGR_RS26740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGR_RS26805	COG0003	Pfam Anion-transporting ATPase
SGR_RS26815	COG1940	carbohydrate kinase activity
SGR_RS26850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGR_RS26860	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SGR_RS26870	COG2193	ferroxidase activity
SGR_RS26875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SGR_RS26880	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SGR_RS26885	COG0515	serine threonine protein kinase
SGR_RS26885	COG2815	serine threonine protein kinase
SGR_RS26890	COG2022	thiamine diphosphate biosynthetic process
SGR_RS26900	COG2022	thiamine diphosphate biosynthetic process
SGR_RS26900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGR_RS26920	COG0352	thiamine-phosphate diphosphorylase activity
SGR_RS26955	COG1121	(ABC) transporter
SGR_RS26965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGR_RS26985	COG0714	Associated with various cellular activities
SGR_RS26995	COG0275	rRNA processing
SGR_RS27005	COG0768	penicillin binding
SGR_RS27010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGR_RS27020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGR_RS27025	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SGR_RS27035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SGR_RS27055	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SGR_RS27060	COG1799	cell septum assembly
SGR_RS27070	COG3599	regulation of cell shape
SGR_RS27075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SGR_RS27085	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SGR_RS27130	COG0587	DNA-directed DNA polymerase activity
SGR_RS27140	COG1432	Conserved Protein
SGR_RS27160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SGR_RS27180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SGR_RS27185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGR_RS27190	COG0131	Imidazoleglycerol-phosphate dehydratase
SGR_RS27200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SGR_RS27205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SGR_RS27210	COG0251	oxidation-reduction process
SGR_RS27215	COG0107	imidazoleglycerol-phosphate synthase activity
SGR_RS27230	COG2508	Transcriptional regulator
SGR_RS27250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SGR_RS27255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGR_RS27275	COG0134	indole-3-glycerol-phosphate synthase activity
SGR_RS27285	COG0133	tryptophan synthase activity
SGR_RS27290	COG0159	tryptophan synthase activity
SGR_RS27300	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SGR_RS27310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SGR_RS27315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGR_RS27345	COG0069	glutamate synthase activity
SGR_RS27345	COG0070	glutamate synthase
SGR_RS27345	COG0067	glutamate synthase
SGR_RS27355	COG0705	Rhomboid family
SGR_RS27380	COG1960	acyl-CoA dehydrogenase activity
SGR_RS27385	COG1960	acyl-CoA dehydrogenase activity
SGR_RS27390	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS27395	COG1309	transcriptional regulator
SGR_RS27405	COG1278	Cold shock
SGR_RS27410	COG0513	Belongs to the DEAD box helicase family
SGR_RS27430	COG1024	Enoyl-CoA hydratase
SGR_RS27435	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS27475	COG0287	Prephenate dehydrogenase
SGR_RS27475	COG1605	Chorismate mutase
SGR_RS27500	COG0737	Belongs to the 5'-nucleotidase family
SGR_RS27545	COG0559	Belongs to the binding-protein-dependent transport system permease family
SGR_RS27555	COG2050	protein possibly involved in aromatic compounds catabolism
SGR_RS27590	COG1643	Atp-dependent helicase
SGR_RS27595	COG2226	methyltransferase
SGR_RS27615	COG0237	dephospho-CoA kinase activity
SGR_RS27630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGR_RS27640	COG0330	HflC and HflK could
SGR_RS27645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SGR_RS27670	COG0436	Aminotransferase
SGR_RS27685	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SGR_RS27690	COG2313	pseudouridylate synthase activity
SGR_RS27700	COG2814	Major facilitator Superfamily
SGR_RS27705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGR_RS27710	COG0584	glycerophosphoryl diester phosphodiesterase
SGR_RS27720	COG0556	nucleotide-excision repair
SGR_RS27750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SGR_RS27775	COG0322	excinuclease ABC activity
SGR_RS27780	COG1660	Displays ATPase and GTPase activities
SGR_RS27785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SGR_RS27790	COG1481	regulation of sporulation
SGR_RS27795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SGR_RS27800	COG0126	phosphoglycerate kinase activity
SGR_RS27805	COG0149	triose-phosphate isomerase activity
SGR_RS27810	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SGR_RS27820	COG0166	Belongs to the GPI family
SGR_RS27835	COG4195	phage-related replication protein
SGR_RS27850	COG0363	glucosamine-6-phosphate deaminase activity
SGR_RS27865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SGR_RS27875	COG0109	protoheme IX farnesyltransferase activity
SGR_RS27910	COG0719	Fe-S assembly protein
SGR_RS27920	COG0396	ATPase activity
SGR_RS27925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGR_RS27930	COG0822	iron-sulfur transferase activity
SGR_RS27935	COG2151	metal-sulfur cluster biosynthetic enzyme
SGR_RS27955	COG3226	Transcriptional regulator
SGR_RS27960	COG2171	N-acyltransferase activity
SGR_RS27965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGR_RS27975	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SGR_RS28010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGR_RS28015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGR_RS28035	COG0768	penicillin binding
SGR_RS28040	COG2197	response regulator
SGR_RS28050	COG1414	Transcriptional regulator
SGR_RS28075	COG1846	Transcriptional regulator
SGR_RS28080	COG1902	pentaerythritol trinitrate reductase activity
SGR_RS28095	COG1917	Cupin 2, conserved barrel domain protein
SGR_RS28110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SGR_RS28135	COG1797	cobyrinic acid a,c-diamide synthase activity
SGR_RS28150	COG1492	cobalamin metabolic process
SGR_RS28155	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SGR_RS28170	COG0235	Class ii aldolase
SGR_RS28190	COG0488	(ABC) transporter
SGR_RS28240	COG3387	PFAM Glycoside hydrolase 15-related
SGR_RS28255	COG1199	ATP-dependent helicase activity
SGR_RS28255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SGR_RS28275	COG1063	alcohol dehydrogenase
SGR_RS28290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGR_RS28295	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SGR_RS28315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SGR_RS28330	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS28335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SGR_RS28345	COG2186	Transcriptional regulator
SGR_RS28365	COG0560	Phosphoserine phosphatase
SGR_RS28365	COG3830	Belongs to the UPF0237 family
SGR_RS28370	COG0842	Transport permease protein
SGR_RS28370	COG1716	ATPase activity
SGR_RS28370	COG1131	(ABC) transporter
SGR_RS28380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SGR_RS28385	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS28390	COG4585	Histidine kinase
SGR_RS28395	COG2197	response regulator
SGR_RS28410	COG1119	ATPase activity
SGR_RS28435	COG1881	PFAM PEBP family protein
SGR_RS28445	COG2094	Belongs to the DNA glycosylase MPG family
SGR_RS28480	COG0647	UMP catabolic process
SGR_RS28485	COG1120	ATPase activity
SGR_RS28505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SGR_RS28510	COG0497	DNA recombination
SGR_RS28535	COG3387	PFAM Glycoside hydrolase 15-related
SGR_RS28540	COG0504	CTP synthase activity
SGR_RS28545	COG0494	nUDIX hydrolase
SGR_RS28555	COG0686	Belongs to the AlaDH PNT family
SGR_RS28570	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SGR_RS28575	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SGR_RS28580	COG1187	pseudouridine synthase activity
SGR_RS28595	COG0494	nUDIX hydrolase
SGR_RS28630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SGR_RS28640	COG1160	GTP binding
SGR_RS28655	COG0438	transferase activity, transferring glycosyl groups
SGR_RS28675	COG0671	phosphoesterase, PA-phosphatase related
SGR_RS28680	COG0477	Major facilitator Superfamily
SGR_RS28685	COG1960	acyl-CoA dehydrogenase activity
SGR_RS28690	COG1799	cell septum assembly
SGR_RS28700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS28705	COG0765	amino acid transport
SGR_RS28725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS28735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS28765	COG0641	radical SAM
SGR_RS28805	COG2201	protein-glutamate methylesterase activity
SGR_RS28825	COG2226	methyltransferase
SGR_RS28840	COG1725	Transcriptional regulator
SGR_RS28850	COG2755	lipolytic protein G-D-S-L family
SGR_RS28860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SGR_RS28870	COG2188	Transcriptional regulator
SGR_RS28875	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SGR_RS28880	COG1309	transcriptional regulator
SGR_RS28885	COG0243	molybdopterin cofactor binding
SGR_RS28890	COG2851	Citrate transporter
SGR_RS28900	COG2318	DinB family
SGR_RS28915	COG2326	polyphosphate kinase activity
SGR_RS28930	COG1960	acyl-CoA dehydrogenase activity
SGR_RS28950	COG0789	Transcriptional regulator
SGR_RS28960	COG3876	Protein conserved in bacteria
SGR_RS28980	COG4935	Belongs to the peptidase S8 family
SGR_RS28980	COG2234	aminopeptidase activity
SGR_RS28985	COG1960	acyl-CoA dehydrogenase activity
SGR_RS28995	COG4948	Mandelate Racemase Muconate Lactonizing
SGR_RS29010	COG2149	membrane
SGR_RS29015	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SGR_RS29020	COG3573	Dehydrogenase
SGR_RS29035	COG1113	amino acid transport
SGR_RS29045	COG3265	gluconokinase activity
SGR_RS29050	COG2186	Transcriptional regulator
SGR_RS29060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGR_RS29065	COG0564	pseudouridine synthase activity
SGR_RS29075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SGR_RS29105	COG0667	Aldo Keto reductase
SGR_RS29110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS29120	COG0598	Magnesium transport protein CorA
SGR_RS29140	COG0215	cysteine-tRNA ligase activity
SGR_RS29150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS29155	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SGR_RS29160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SGR_RS29165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SGR_RS29170	COG1414	Transcriptional regulator
SGR_RS29175	COG0646	methionine synthase
SGR_RS29175	COG1410	methionine synthase
SGR_RS29180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGR_RS29190	COG2197	response regulator
SGR_RS29200	COG0517	IMP dehydrogenase activity
SGR_RS29200	COG1994	Peptidase M50
SGR_RS29220	COG1222	aaa ATPase
SGR_RS29225	COG4122	O-methyltransferase activity
SGR_RS29235	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SGR_RS29240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SGR_RS29245	COG1609	Transcriptional regulator
SGR_RS29255	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SGR_RS29260	COG0545	Peptidyl-prolyl cis-trans isomerase
SGR_RS29270	COG2378	regulation of single-species biofilm formation
SGR_RS29290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SGR_RS29295	COG0805	protein transport
SGR_RS29335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SGR_RS29340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SGR_RS29385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGR_RS29390	COG0517	IMP dehydrogenase activity
SGR_RS29390	COG4175	Glycine betaine
SGR_RS29435	COG1404	Belongs to the peptidase S8 family
SGR_RS29455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SGR_RS29465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SGR_RS29470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SGR_RS29475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SGR_RS29480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGR_RS29485	COG5002	protein histidine kinase activity
SGR_RS29490	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SGR_RS29495	COG0072	phenylalanine-tRNA ligase activity
SGR_RS29495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGR_RS29525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGR_RS29655	COG1649	PFAM Uncharacterised BCR, COG1649
SGR_RS29665	COG0697	spore germination
SGR_RS29740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SGR_RS29745	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SGR_RS29750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SGR_RS29755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGR_RS29760	COG1438	arginine binding
SGR_RS29770	COG0137	argininosuccinate synthase activity
SGR_RS29775	COG0165	Argininosuccinate lyase
SGR_RS29785	COG3973	AAA domain
SGR_RS29795	COG0477	Major facilitator Superfamily
SGR_RS29835	COG2011	ABC-type metal ion transport system permease component
SGR_RS29840	COG1464	Belongs to the NlpA lipoprotein family
SGR_RS29855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SGR_RS29860	COG1648	precorrin-2 dehydrogenase activity
SGR_RS29860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SGR_RS29915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGR_RS29925	COG0456	acetyltransferase
SGR_RS29970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SGR_RS29985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SGR_RS29990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SGR_RS30010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SGR_RS30015	COG1560	Kdo2-lipid A biosynthetic process
SGR_RS30020	COG0438	transferase activity, transferring glycosyl groups
SGR_RS30030	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SGR_RS30035	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SGR_RS30040	COG0217	transcriptional regulatory protein
SGR_RS30045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SGR_RS30050	COG0632	four-way junction helicase activity
SGR_RS30055	COG2255	four-way junction helicase activity
SGR_RS30065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGR_RS30070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGR_RS30075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SGR_RS30080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SGR_RS30085	COG1196	nuclear chromosome segregation
SGR_RS30090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGR_RS30100	COG0124	histidyl-tRNA synthetase
SGR_RS30120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SGR_RS30140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SGR_RS30145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SGR_RS30155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SGR_RS30160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SGR_RS30165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGR_RS30170	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SGR_RS30180	COG0006	proline dipeptidase activity
SGR_RS30185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SGR_RS30190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGR_RS30200	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SGR_RS30205	COG0540	Belongs to the ATCase OTCase family
SGR_RS30210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGR_RS30220	COG0505	Belongs to the CarA family
SGR_RS30225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SGR_RS30230	COG0167	dihydroorotate dehydrogenase activity
SGR_RS30235	COG0284	orotidine-5'-phosphate decarboxylase activity
SGR_RS30250	COG1758	RNA polymerase activity
SGR_RS30260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SGR_RS30275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SGR_RS30285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SGR_RS30290	COG2390	Transcriptional regulator
SGR_RS30305	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS30315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGR_RS30340	COG0604	alcohol dehydrogenase
SGR_RS30340	COG3321	synthase
SGR_RS30375	COG2409	Drug exporters of the RND superfamily
SGR_RS30380	COG1309	transcriptional regulator
SGR_RS30390	COG2233	PERMEase
SGR_RS30395	COG0738	Major facilitator superfamily
SGR_RS30400	COG1940	carbohydrate kinase activity
SGR_RS30405	COG0702	epimerase
SGR_RS30425	COG3201	nicotinamide mononucleotide transporter
SGR_RS30430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGR_RS30430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGR_RS30435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SGR_RS30440	COG0140	phosphoribosyl-ATP diphosphatase activity
SGR_RS30445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SGR_RS30495	COG1960	acyl-CoA dehydrogenase activity
SGR_RS30515	COG1216	Glycosyl transferase, family 2
SGR_RS30530	COG2270	Major facilitator Superfamily
SGR_RS30540	COG2364	Membrane
SGR_RS30610	COG2018	Roadblock/LC7 domain
SGR_RS30640	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SGR_RS30655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SGR_RS30665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGR_RS30695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SGR_RS30715	COG1716	ATPase activity
SGR_RS30735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SGR_RS30745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SGR_RS30745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SGR_RS30775	COG0384	phenazine biosynthesis protein PhzF
SGR_RS30785	COG2814	Major facilitator Superfamily
SGR_RS30815	COG1695	Transcriptional regulator
SGR_RS30855	COG0697	spore germination
SGR_RS30860	COG0583	DNA-binding transcription factor activity
SGR_RS30875	COG2197	response regulator
SGR_RS30925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGR_RS30945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS30955	COG0667	Aldo Keto reductase
SGR_RS30975	COG2076	Multidrug Resistance protein
SGR_RS30990	COG2318	DinB family
SGR_RS31010	COG0789	Transcriptional regulator
SGR_RS31025	COG0069	glutamate synthase activity
SGR_RS31030	COG0659	secondary active sulfate transmembrane transporter activity
SGR_RS31045	COG0596	Alpha beta hydrolase
SGR_RS31085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SGR_RS31105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SGR_RS31145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SGR_RS31150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGR_RS31155	COG0243	molybdopterin cofactor binding
SGR_RS31165	COG1968	undecaprenyl-diphosphatase activity
SGR_RS31180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGR_RS31225	COG1832	CoA-binding protein
SGR_RS31230	COG1739	Uncharacterized protein family UPF0029
SGR_RS31240	COG0420	3'-5' exonuclease activity
SGR_RS31245	COG0419	ATPase involved in DNA repair
SGR_RS31250	COG1522	sequence-specific DNA binding
SGR_RS31275	COG0626	cystathionine gamma-synthase activity
SGR_RS31300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGR_RS31310	COG2267	carboxylic ester hydrolase activity
SGR_RS31315	COG1595	DNA-templated transcription, initiation
SGR_RS31320	COG2188	Transcriptional regulator
SGR_RS31325	COG1940	carbohydrate kinase activity
SGR_RS31330	COG2197	response regulator
SGR_RS31335	COG4585	Histidine kinase
SGR_RS31355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SGR_RS31375	COG0456	acetyltransferase
SGR_RS31390	COG2226	methyltransferase
SGR_RS31395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SGR_RS31400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SGR_RS31405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SGR_RS31425	COG0583	DNA-binding transcription factor activity
SGR_RS31430	COG1280	lysine exporter protein (LysE YggA)
SGR_RS31445	COG0740	serine-type endopeptidase activity
SGR_RS31460	COG1309	transcriptional regulator
SGR_RS31465	COG0831	urea catabolic process
SGR_RS31470	COG0832	Belongs to the urease beta subunit family
SGR_RS31475	COG0804	urea catabolic process
SGR_RS31485	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SGR_RS31490	COG0829	nickel cation binding
SGR_RS31505	COG0204	Acyl-transferase
SGR_RS31520	COG0205	6-phosphofructokinase activity
SGR_RS31525	COG3442	glutamine amidotransferase
SGR_RS31535	COG0242	peptide deformylase activity
SGR_RS31545	COG1960	acyl-CoA dehydrogenase activity
SGR_RS31550	COG0386	Belongs to the glutathione peroxidase family
SGR_RS31575	COG1946	Acyl-CoA thioesterase
SGR_RS31590	COG1793	dna ligase
SGR_RS31605	COG1132	(ABC) transporter
SGR_RS31615	COG0673	inositol 2-dehydrogenase activity
SGR_RS31620	COG0277	FAD linked oxidase domain protein
SGR_RS31630	COG1132	(ABC) transporter
SGR_RS31640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SGR_RS31645	COG2072	flavoprotein involved in K transport
SGR_RS31650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS31655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGR_RS31660	COG1116	anion transmembrane transporter activity
SGR_RS31665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGR_RS31720	COG0464	growth
SGR_RS31725	COG1404	Belongs to the peptidase S8 family
SGR_RS31730	COG1674	ftsk spoiiie
SGR_RS31750	COG4842	Belongs to the WXG100 family
SGR_RS31785	COG1136	(ABC) transporter
SGR_RS31815	COG3629	intracellular signal transduction
SGR_RS31815	COG3903	Transcriptional regulator
SGR_RS31840	COG3321	synthase
SGR_RS31840	COG0604	alcohol dehydrogenase
SGR_RS31845	COG3321	synthase
SGR_RS31845	COG0604	alcohol dehydrogenase
SGR_RS31860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGR_RS31880	COG1960	acyl-CoA dehydrogenase activity
SGR_RS31910	COG3629	intracellular signal transduction
SGR_RS31920	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SGR_RS31930	COG1408	metallophosphoesterase
SGR_RS31950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SGR_RS31955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS31960	COG1120	ATPase activity
SGR_RS31965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SGR_RS31985	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SGR_RS32000	COG1891	lyase activity
SGR_RS32025	COG4166	transmembrane transport
SGR_RS32050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS32055	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS32085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SGR_RS32095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGR_RS32105	COG0444	Belongs to the ABC transporter superfamily
SGR_RS32115	COG0747	negative chemotaxis
SGR_RS32125	COG3458	cephalosporin-C deacetylase activity
SGR_RS32135	COG2186	Transcriptional regulator
SGR_RS32140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGR_RS32150	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SGR_RS32170	COG2080	2 iron, 2 sulfur cluster binding
SGR_RS32175	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SGR_RS32180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SGR_RS32205	COG2890	protein-(glutamine-N5) methyltransferase activity
SGR_RS32260	COG0542	response to heat
SGR_RS32275	COG0402	S-adenosylhomocysteine deaminase activity
SGR_RS32280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGR_RS32285	COG1802	Transcriptional regulator
SGR_RS32295	COG2835	tetraacyldisaccharide 4'-kinase activity
SGR_RS32315	COG4981	capsule polysaccharide biosynthetic process
SGR_RS32320	COG0500	methyltransferase
SGR_RS32345	COG1012	belongs to the aldehyde dehydrogenase family
SGR_RS32350	COG0174	glutamine synthetase
SGR_RS32360	COG0531	amino acid
SGR_RS32365	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SGR_RS32400	COG1253	flavin adenine dinucleotide binding
SGR_RS32435	COG3469	chitinase activity
SGR_RS32440	COG0667	Aldo Keto reductase
SGR_RS32445	COG0515	serine threonine protein kinase
SGR_RS32445	COG2815	serine threonine protein kinase
SGR_RS32450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGR_RS32465	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS32475	COG2706	6-phosphogluconolactonase activity
SGR_RS32490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SGR_RS32535	COG0671	phosphoesterase, PA-phosphatase related
SGR_RS32555	COG0584	glycerophosphoryl diester phosphodiesterase
SGR_RS32600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SGR_RS32630	COG1940	carbohydrate kinase activity
SGR_RS32650	COG0445	tRNA wobble uridine modification
SGR_RS32675	COG2223	nitrite transmembrane transporter activity
SGR_RS32680	COG1940	carbohydrate kinase activity
SGR_RS32720	COG0702	epimerase
SGR_RS32735	COG1349	DNA-binding transcription factor activity
SGR_RS32745	COG0464	growth
SGR_RS32765	COG0477	Major facilitator Superfamily
SGR_RS32785	COG2205	protein histidine kinase activity
SGR_RS32815	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SGR_RS32875	COG1132	(ABC) transporter
SGR_RS32880	COG1132	(ABC) transporter
SGR_RS32890	COG1120	ATPase activity
SGR_RS32895	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS32900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS32905	COG2207	Transcriptional regulator
SGR_RS32905	COG4753	response regulator
SGR_RS32910	COG0659	secondary active sulfate transmembrane transporter activity
SGR_RS32915	COG0288	reversible hydration of carbon dioxide
SGR_RS32920	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SGR_RS32930	COG1132	(ABC) transporter
SGR_RS32935	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS32940	COG0328	RNA-DNA hybrid ribonuclease activity
SGR_RS33000	COG1879	ABC-type sugar transport system periplasmic component
SGR_RS33005	COG1129	ABC transporter
SGR_RS33015	COG1172	Belongs to the binding-protein-dependent transport system permease family
SGR_RS33020	COG1609	Transcriptional regulator
SGR_RS33035	COG1874	Beta-galactosidase
SGR_RS33035	COG0366	Alpha amylase catalytic
SGR_RS33070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS33075	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS33080	COG1120	ATPase activity
SGR_RS33115	COG1295	ribonuclease BN
SGR_RS33115	COG1959	2 iron, 2 sulfur cluster binding
SGR_RS33170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGR_RS33195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS33200	COG1120	ATPase activity
SGR_RS33220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SGR_RS33230	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGR_RS33230	COG0824	Thioesterase
SGR_RS33235	COG1250	3-hydroxyacyl-CoA dehydrogenase
SGR_RS33240	COG3246	L-lysine catabolic process to acetate
SGR_RS33245	COG1309	transcriptional regulator
SGR_RS33250	COG1191	sigma factor activity
SGR_RS33280	COG0488	(ABC) transporter
SGR_RS33295	COG1461	Dihydroxyacetone kinase
SGR_RS33300	COG2376	Dihydroxyacetone kinase
SGR_RS33340	COG0546	phosphoglycolate phosphatase activity
SGR_RS33345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SGR_RS33375	COG0596	Alpha beta hydrolase
SGR_RS33380	COG0784	Response regulator, receiver
SGR_RS33385	COG4251	negative regulation of phosphorylation
SGR_RS33415	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SGR_RS33420	COG3285	dna ligase
SGR_RS33420	COG1793	dna ligase
SGR_RS33425	COG0587	DNA-directed DNA polymerase activity
SGR_RS33430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SGR_RS33450	COG1131	(ABC) transporter
SGR_RS33455	COG3559	Exporter of polyketide antibiotics
SGR_RS33510	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SGR_RS33515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS33520	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS33525	COG1120	ATPase activity
SGR_RS33530	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SGR_RS33535	COG1132	(ABC) transporter
SGR_RS33545	COG1132	(ABC) transporter
SGR_RS33550	COG2382	esterase
SGR_RS33565	COG0148	phosphopyruvate hydratase activity
SGR_RS33605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SGR_RS33610	COG3433	isochorismatase activity
SGR_RS33610	COG1535	isochorismatase
SGR_RS33615	COG1535	isochorismatase
SGR_RS33615	COG3433	isochorismatase activity
SGR_RS33620	COG1021	2,3-dihydroxybenzoate-AMP ligase
SGR_RS33625	COG1169	isochorismate synthase
SGR_RS33630	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS33635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGR_RS33640	COG2382	esterase
SGR_RS33645	COG0477	Major facilitator Superfamily
SGR_RS33655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGR_RS33665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGR_RS33670	COG1120	ATPase activity
SGR_RS33700	COG2365	Tyrosine phosphatase family
SGR_RS33750	COG2080	2 iron, 2 sulfur cluster binding
SGR_RS33755	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SGR_RS33760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SGR_RS33775	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SGR_RS33780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SGR_RS33800	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
SGR_RS33800	COG2066	Belongs to the glutaminase family
SGR_RS33805	COG2356	endonuclease I
SGR_RS33830	COG2813	Specifically methylates the guanine in position
SGR_RS33835	COG1960	acyl-CoA dehydrogenase activity
SGR_RS33840	COG0300	oxidoreductase activity
SGR_RS33840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGR_RS33840	COG3321	synthase
SGR_RS33840	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS33840	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS33845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGR_RS33845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGR_RS33845	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SGR_RS33845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGR_RS33845	COG3321	synthase
SGR_RS33845	COG3321	synthase
SGR_RS33845	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SGR_RS33845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGR_RS33855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGR_RS33865	COG3629	intracellular signal transduction
SGR_RS33865	COG3903	Transcriptional regulator
SGR_RS33875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGR_RS33880	COG0367	asparagine synthase
SGR_RS33885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGR_RS33885	COG0300	oxidoreductase activity
SGR_RS33885	COG4221	oxidoreductase activity
SGR_RS33885	COG3321	synthase
SGR_RS33890	COG0583	DNA-binding transcription factor activity
SGR_RS33905	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS33930	COG0515	serine threonine protein kinase
SGR_RS33950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGR_RS33955	COG2070	2-Nitropropane dioxygenase
SGR_RS33980	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SGR_RS33980	COG1672	PFAM Archaeal ATPase
SGR_RS34010	COG2366	antibiotic biosynthetic process
SGR_RS34015	COG0318	PFAM AMP-dependent synthetase and ligase
SGR_RS34025	COG0765	amino acid transport
SGR_RS34030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGR_RS34060	COG2770	Histidine kinase
SGR_RS34060	COG2208	phosphoserine phosphatase activity
SGR_RS34080	COG1191	sigma factor activity
SGR_RS34090	COG4106	trans-aconitate 2-methyltransferase activity
SGR_RS34095	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGR_RS34115	COG0142	geranyltranstransferase activity
SGR_RS34125	COG1024	Enoyl-CoA hydratase
SGR_RS34140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SGR_RS34190	COG0254	rRNA binding
SGR_RS34220	COG2318	DinB family
SGR_RS34250	COG0596	Alpha beta hydrolase
SGR_RS34265	COG0681	Belongs to the peptidase S26 family
SGR_RS34275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGR_RS34290	COG1349	DNA-binding transcription factor activity
SGR_RS34305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGR_RS34340	COG1175	transmembrane transport
SGR_RS34345	COG0395	ABC-type sugar transport system, permease component
SGR_RS34350	COG0366	Alpha amylase catalytic
SGR_RS34360	COG2318	DinB family
SGR_RS34375	COG0642	Histidine kinase
SGR_RS34405	COG0702	epimerase
SGR_RS34415	COG1064	alcohol dehydrogenase
SGR_RS34420	COG0640	Transcriptional regulator
SGR_RS34425	COG1902	pentaerythritol trinitrate reductase activity
SGR_RS34450	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SGR_RS34455	COG3457	Alanine racemase
SGR_RS34460	COG0626	cystathionine gamma-synthase activity
SGR_RS34465	COG1735	metal-dependent hydrolase with the TIM-barrel fold
SGR_RS34485	COG2188	Transcriptional regulator
SGR_RS34495	COG1136	(ABC) transporter
SGR_RS34500	COG0577	efflux transmembrane transporter activity
SGR_RS34525	COG0583	DNA-binding transcription factor activity
SGR_RS34540	COG1764	response to oxidative stress
SGR_RS34545	COG1846	Transcriptional regulator
SGR_RS34555	COG0477	Major facilitator Superfamily
SGR_RS34595	COG5297	Belongs to the glycosyl hydrolase family 6
SGR_RS34610	COG0142	geranyltranstransferase activity
SGR_RS34620	COG4941	Belongs to the sigma-70 factor family
SGR_RS34625	COG3795	YCII-related domain
SGR_RS34650	COG4977	sequence-specific DNA binding
SGR_RS34685	COG4585	Histidine kinase
SGR_RS34690	COG2197	response regulator
SGR_RS34695	COG0574	Belongs to the PEP-utilizing enzyme family
SGR_RS34695	COG3848	Pyruvate phosphate dikinase
SGR_RS34700	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS34705	COG2072	flavoprotein involved in K transport
SGR_RS34745	COG2267	carboxylic ester hydrolase activity
SGR_RS34785	COG2814	Major facilitator Superfamily
SGR_RS34865	COG2226	methyltransferase
SGR_RS34930	COG2197	response regulator
SGR_RS34955	COG0667	Aldo Keto reductase
SGR_RS34985	COG0640	Transcriptional regulator
SGR_RS34995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SGR_RS35040	COG3293	Transposase
SGR_RS35065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SGR_RS35245	COG0431	NADPH-dependent FMN reductase
SGR_RS35250	COG0477	Major facilitator Superfamily
SGR_RS35275	COG2837	iron assimilation
SGR_RS35290	COG0142	geranyltranstransferase activity
SGR_RS35310	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGR_RS35345	COG1028	Short-chain dehydrogenase reductase Sdr
SGR_RS35350	COG1309	transcriptional regulator
SGR_RS35425	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SGR_RS35445	COG1335	isochorismatase
SGR_RS35455	COG2801	Transposase and inactivated derivatives
SGR_RS35605	COG0443	Heat shock 70 kDa protein
SGR_RS35650	COG0267	Belongs to the bacterial ribosomal protein bL33 family