locus-tag	class	description
SHJG_RS00140	COG1902	pentaerythritol trinitrate reductase activity
SHJG_RS00155	COG1475	DNA binding
SHJG_RS00215	COG0484	heat shock protein binding
SHJG_RS00280	COG3328	transposase activity
SHJG_RS00305	COG1192	Involved in chromosome partitioning
SHJG_RS00335	COG3415	Transposase
SHJG_RS00335	COG2801	Transposase and inactivated derivatives
SHJG_RS00370	COG3547	Transposase (IS116 IS110 IS902 family)
SHJG_RS00395	COG3547	Transposase (IS116 IS110 IS902 family)
SHJG_RS00425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SHJG_RS00430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SHJG_RS00460	COG2801	Transposase and inactivated derivatives
SHJG_RS00460	COG3415	Transposase
SHJG_RS00470	COG2826	transposase and inactivated derivatives, IS30 family
SHJG_RS00505	COG2197	response regulator
SHJG_RS00565	COG3290	protein histidine kinase activity
SHJG_RS00595	COG1063	alcohol dehydrogenase
SHJG_RS00630	COG1414	Transcriptional regulator
SHJG_RS00655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS00680	COG3345	alpha-galactosidase
SHJG_RS00690	COG2755	lipolytic protein G-D-S-L family
SHJG_RS00730	COG3547	Transposase (IS116 IS110 IS902 family)
SHJG_RS00765	COG2801	Transposase and inactivated derivatives
SHJG_RS00770	COG2963	transposase activity
SHJG_RS00775	COG2801	Transposase and inactivated derivatives
SHJG_RS00850	COG3903	Transcriptional regulator
SHJG_RS00850	COG3629	intracellular signal transduction
SHJG_RS00900	COG0596	Alpha beta hydrolase
SHJG_RS00905	COG3903	Transcriptional regulator
SHJG_RS00905	COG3629	intracellular signal transduction
SHJG_RS00935	COG2801	Transposase and inactivated derivatives
SHJG_RS00955	COG0604	alcohol dehydrogenase
SHJG_RS00955	COG3321	synthase
SHJG_RS00985	COG0154	amidase activity
SHJG_RS01020	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS01040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SHJG_RS01050	COG0655	NAD(P)H dehydrogenase (quinone) activity
SHJG_RS01060	COG1672	PFAM Archaeal ATPase
SHJG_RS01060	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJG_RS01080	COG0406	alpha-ribazole phosphatase activity
SHJG_RS01100	COG0395	ABC-type sugar transport system, permease component
SHJG_RS01105	COG1175	transmembrane transport
SHJG_RS01130	COG1335	isochorismatase
SHJG_RS01150	COG3547	Transposase (IS116 IS110 IS902 family)
SHJG_RS01165	COG0179	Fumarylacetoacetate (FAA) hydrolase
SHJG_RS01190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS01195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS01230	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS01250	COG1335	isochorismatase
SHJG_RS01255	COG1733	regulation of RNA biosynthetic process
SHJG_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
SHJG_RS01295	COG1902	pentaerythritol trinitrate reductase activity
SHJG_RS01295	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJG_RS01315	COG1335	isochorismatase
SHJG_RS01320	COG1733	regulation of RNA biosynthetic process
SHJG_RS01330	COG1802	Transcriptional regulator
SHJG_RS01345	COG2801	Transposase and inactivated derivatives
SHJG_RS01350	COG2963	transposase activity
SHJG_RS01365	COG0596	Alpha beta hydrolase
SHJG_RS01370	COG0659	secondary active sulfate transmembrane transporter activity
SHJG_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS01400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SHJG_RS01400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SHJG_RS01405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS01430	COG3386	PFAM SMP-30 Gluconolaconase
SHJG_RS01445	COG4948	Mandelate Racemase Muconate Lactonizing
SHJG_RS01450	COG2186	Transcriptional regulator
SHJG_RS01465	COG0395	ABC-type sugar transport system, permease component
SHJG_RS01470	COG1175	transmembrane transport
SHJG_RS01475	COG1653	transport
SHJG_RS01485	COG3469	chitinase activity
SHJG_RS01570	COG2963	transposase activity
SHJG_RS01575	COG2801	Transposase and inactivated derivatives
SHJG_RS01585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SHJG_RS01590	COG2801	Transposase and inactivated derivatives
SHJG_RS01595	COG2963	transposase activity
SHJG_RS01600	COG3547	Transposase (IS116 IS110 IS902 family)
SHJG_RS01625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SHJG_RS01630	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SHJG_RS01640	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SHJG_RS01645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SHJG_RS01665	COG0673	inositol 2-dehydrogenase activity
SHJG_RS01670	COG1216	Glycosyl transferase, family 2
SHJG_RS01685	COG3387	PFAM Glycoside hydrolase 15-related
SHJG_RS01750	COG5434	Belongs to the glycosyl hydrolase 28 family
SHJG_RS01765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJG_RS01770	COG2249	NAD(P)H dehydrogenase (quinone) activity
SHJG_RS01800	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS01805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SHJG_RS01810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJG_RS01815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJG_RS01820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJG_RS01860	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS01905	COG0604	alcohol dehydrogenase
SHJG_RS01905	COG3321	synthase
SHJG_RS01930	COG3540	Alkaline phosphatase
SHJG_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS02040	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SHJG_RS02060	COG0488	(ABC) transporter
SHJG_RS02065	COG0488	(ABC) transporter
SHJG_RS02085	COG3903	Transcriptional regulator
SHJG_RS02085	COG3629	intracellular signal transduction
SHJG_RS02110	COG2801	Transposase and inactivated derivatives
SHJG_RS02110	COG3415	Transposase
SHJG_RS02140	COG1764	response to oxidative stress
SHJG_RS02145	COG0242	peptide deformylase activity
SHJG_RS02175	COG3415	Transposase
SHJG_RS02175	COG2801	Transposase and inactivated derivatives
SHJG_RS02220	COG0741	lytic transglycosylase activity
SHJG_RS02225	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJG_RS02280	COG0077	Prephenate dehydratase
SHJG_RS02280	COG1605	Chorismate mutase
SHJG_RS02305	COG0477	Major facilitator Superfamily
SHJG_RS02430	COG2855	membrane
SHJG_RS02445	COG0753	catalase activity
SHJG_RS02475	COG2755	lipolytic protein G-D-S-L family
SHJG_RS02500	COG2234	aminopeptidase activity
SHJG_RS02525	COG0242	peptide deformylase activity
SHJG_RS02550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SHJG_RS02565	COG2130	NADP-dependent
SHJG_RS02580	COG1073	alpha beta
SHJG_RS02595	COG1309	transcriptional regulator
SHJG_RS02635	COG0513	Belongs to the DEAD box helicase family
SHJG_RS02640	COG1278	Cold shock
SHJG_RS02645	COG3629	intracellular signal transduction
SHJG_RS02645	COG3903	Transcriptional regulator
SHJG_RS02655	COG1073	alpha beta
SHJG_RS02660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SHJG_RS02665	COG0745	RESPONSE REGULATOR receiver
SHJG_RS02670	COG2205	protein histidine kinase activity
SHJG_RS02675	COG1686	Belongs to the peptidase S11 family
SHJG_RS02705	COG2027	D-alanyl-D-alanine carboxypeptidase
SHJG_RS02725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SHJG_RS02730	COG0028	Belongs to the TPP enzyme family
SHJG_RS02750	COG0577	efflux transmembrane transporter activity
SHJG_RS02755	COG4585	Histidine kinase
SHJG_RS02760	COG2197	response regulator
SHJG_RS02775	COG2197	response regulator
SHJG_RS02780	COG2197	response regulator
SHJG_RS02805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SHJG_RS02820	COG4166	transmembrane transport
SHJG_RS02825	COG0601	transmembrane transport
SHJG_RS02830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJG_RS02840	COG4608	Belongs to the ABC transporter superfamily
SHJG_RS02850	COG1192	Involved in chromosome partitioning
SHJG_RS02865	COG0395	ABC-type sugar transport system, permease component
SHJG_RS02870	COG1175	transmembrane transport
SHJG_RS02880	COG1609	Transcriptional regulator
SHJG_RS02890	COG1136	(ABC) transporter
SHJG_RS02890	COG0577	efflux transmembrane transporter activity
SHJG_RS02895	COG1136	(ABC) transporter
SHJG_RS02895	COG0577	efflux transmembrane transporter activity
SHJG_RS02910	COG0745	RESPONSE REGULATOR receiver
SHJG_RS02915	COG5002	protein histidine kinase activity
SHJG_RS02920	COG1309	transcriptional regulator
SHJG_RS02925	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS02930	COG0667	Aldo Keto reductase
SHJG_RS02950	COG0667	Aldo Keto reductase
SHJG_RS02960	COG0745	RESPONSE REGULATOR receiver
SHJG_RS02970	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS02975	COG2267	carboxylic ester hydrolase activity
SHJG_RS02990	COG1271	oxidase subunit
SHJG_RS03005	COG2837	iron assimilation
SHJG_RS03045	COG0697	spore germination
SHJG_RS03130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJG_RS03135	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS03145	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS03150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS03175	COG4555	ABC transporter
SHJG_RS03230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJG_RS03240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS03270	COG1131	(ABC) transporter
SHJG_RS03290	COG2267	carboxylic ester hydrolase activity
SHJG_RS03295	COG0535	radical SAM domain protein
SHJG_RS03305	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
SHJG_RS03310	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SHJG_RS03320	COG2133	pyrroloquinoline quinone binding
SHJG_RS03370	COG0438	transferase activity, transferring glycosyl groups
SHJG_RS03380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SHJG_RS03385	COG1472	Belongs to the glycosyl hydrolase 3 family
SHJG_RS03390	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS03430	COG0583	DNA-binding transcription factor activity
SHJG_RS03435	COG0667	Aldo Keto reductase
SHJG_RS03440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJG_RS03445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SHJG_RS03450	COG1993	acr, cog1993
SHJG_RS03455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SHJG_RS03480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SHJG_RS03490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJG_RS03505	COG4948	Mandelate Racemase Muconate Lactonizing
SHJG_RS03515	COG1846	Transcriptional regulator
SHJG_RS03550	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS03555	COG0656	L-ascorbic acid biosynthetic process
SHJG_RS03580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SHJG_RS03585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SHJG_RS03590	COG2080	2 iron, 2 sulfur cluster binding
SHJG_RS03610	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SHJG_RS03615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJG_RS03625	COG1737	Transcriptional regulator
SHJG_RS03630	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SHJG_RS03685	COG1132	(ABC) transporter
SHJG_RS03690	COG1937	Protein conserved in bacteria
SHJG_RS03695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJG_RS03695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SHJG_RS03705	COG0730	response to heat
SHJG_RS03710	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SHJG_RS03725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SHJG_RS03725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SHJG_RS03730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SHJG_RS03735	COG0254	rRNA binding
SHJG_RS03740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SHJG_RS03770	COG3795	YCII-related domain
SHJG_RS03775	COG4941	Belongs to the sigma-70 factor family
SHJG_RS03850	COG0673	inositol 2-dehydrogenase activity
SHJG_RS03860	COG1172	Belongs to the binding-protein-dependent transport system permease family
SHJG_RS03865	COG1129	ABC transporter
SHJG_RS03870	COG1940	carbohydrate kinase activity
SHJG_RS03905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS03920	COG2318	DinB family
SHJG_RS04000	COG1846	Transcriptional regulator
SHJG_RS04005	COG0477	Major facilitator Superfamily
SHJG_RS04015	COG1309	transcriptional regulator
SHJG_RS04090	COG2267	carboxylic ester hydrolase activity
SHJG_RS04105	COG1335	isochorismatase
SHJG_RS04115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS04135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJG_RS04140	COG1024	Enoyl-CoA hydratase
SHJG_RS04145	COG1024	Enoyl-CoA hydratase
SHJG_RS04145	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJG_RS04155	COG0604	alcohol dehydrogenase
SHJG_RS04165	COG0596	Alpha beta hydrolase
SHJG_RS04165	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJG_RS04170	COG0583	DNA-binding transcription factor activity
SHJG_RS04175	COG3903	Transcriptional regulator
SHJG_RS04175	COG3629	intracellular signal transduction
SHJG_RS04180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SHJG_RS04195	COG2197	response regulator
SHJG_RS04200	COG0583	DNA-binding transcription factor activity
SHJG_RS04215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SHJG_RS04215	COG0596	Alpha beta hydrolase
SHJG_RS04215	COG2226	methyltransferase
SHJG_RS04220	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJG_RS04220	COG1672	PFAM Archaeal ATPase
SHJG_RS04250	COG3383	formate dehydrogenase (NAD+) activity
SHJG_RS04260	COG2197	response regulator
SHJG_RS04270	COG2267	carboxylic ester hydrolase activity
SHJG_RS04275	COG3903	Transcriptional regulator
SHJG_RS04275	COG3629	intracellular signal transduction
SHJG_RS04310	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS04315	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS04330	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SHJG_RS04340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SHJG_RS04360	COG0254	rRNA binding
SHJG_RS04365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SHJG_RS04370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJG_RS04380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJG_RS04395	COG1335	isochorismatase
SHJG_RS04420	COG0583	DNA-binding transcription factor activity
SHJG_RS04430	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJG_RS04430	COG1672	PFAM Archaeal ATPase
SHJG_RS04455	COG0667	Aldo Keto reductase
SHJG_RS04470	COG1733	regulation of RNA biosynthetic process
SHJG_RS04475	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJG_RS04475	COG0596	Alpha beta hydrolase
SHJG_RS04480	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJG_RS04480	COG1672	PFAM Archaeal ATPase
SHJG_RS04495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SHJG_RS04525	COG2814	Major facilitator Superfamily
SHJG_RS04535	COG0656	L-ascorbic acid biosynthetic process
SHJG_RS04540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS04550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SHJG_RS04580	COG0765	amino acid transport
SHJG_RS04590	COG1609	Transcriptional regulator
SHJG_RS04595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJG_RS04595	COG2022	thiamine diphosphate biosynthetic process
SHJG_RS04600	COG0673	inositol 2-dehydrogenase activity
SHJG_RS04605	COG1902	pentaerythritol trinitrate reductase activity
SHJG_RS04605	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJG_RS04615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SHJG_RS04625	COG1131	(ABC) transporter
SHJG_RS04640	COG0142	geranyltranstransferase activity
SHJG_RS04680	COG0477	Major facilitator Superfamily
SHJG_RS04720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS04735	COG0583	DNA-binding transcription factor activity
SHJG_RS04745	COG0431	NADPH-dependent FMN reductase
SHJG_RS04755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS04820	COG0019	diaminopimelate decarboxylase activity
SHJG_RS04835	COG0745	RESPONSE REGULATOR receiver
SHJG_RS04845	COG0546	phosphoglycolate phosphatase activity
SHJG_RS04860	COG2271	Major facilitator Superfamily
SHJG_RS04865	COG0583	DNA-binding transcription factor activity
SHJG_RS04875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJG_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS04960	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS04970	COG2814	Major facilitator Superfamily
SHJG_RS04985	COG2267	carboxylic ester hydrolase activity
SHJG_RS05060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJG_RS05065	COG2188	Transcriptional regulator
SHJG_RS05110	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS05135	COG1349	DNA-binding transcription factor activity
SHJG_RS05140	COG2223	nitrite transmembrane transporter activity
SHJG_RS05160	COG3572	ergothioneine biosynthetic process
SHJG_RS05165	COG2318	DinB family
SHJG_RS05195	COG2353	YceI-like domain
SHJG_RS05200	COG2353	YceI-like domain
SHJG_RS05210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS05235	COG0596	Alpha beta hydrolase
SHJG_RS05285	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SHJG_RS05295	COG2345	Transcriptional regulator
SHJG_RS05310	COG0671	phosphoesterase, PA-phosphatase related
SHJG_RS05320	COG3321	synthase
SHJG_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS05320	COG0604	alcohol dehydrogenase
SHJG_RS05325	COG0657	acetylesterase activity
SHJG_RS05345	COG2814	Major facilitator Superfamily
SHJG_RS05350	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS05355	COG0596	Alpha beta hydrolase
SHJG_RS05420	COG3345	alpha-galactosidase
SHJG_RS05430	COG3693	PFAM glycoside hydrolase, family 10
SHJG_RS05445	COG2188	Transcriptional regulator
SHJG_RS05465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SHJG_RS05505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJG_RS05510	COG0028	Belongs to the TPP enzyme family
SHJG_RS05515	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS05590	COG0596	Alpha beta hydrolase
SHJG_RS05620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SHJG_RS05660	COG2814	Major facilitator Superfamily
SHJG_RS05685	COG0583	DNA-binding transcription factor activity
SHJG_RS05705	COG1131	(ABC) transporter
SHJG_RS05710	COG4585	Histidine kinase
SHJG_RS05715	COG2197	response regulator
SHJG_RS05735	COG4221	oxidoreductase activity
SHJG_RS05785	COG1301	dicarboxylic acid transport
SHJG_RS05790	COG2828	Protein conserved in bacteria
SHJG_RS05805	COG0596	Alpha beta hydrolase
SHJG_RS05850	COG3321	synthase
SHJG_RS05850	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS05850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS05850	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS05850	COG0300	oxidoreductase activity
SHJG_RS05865	COG2175	clavaminate synthase activity
SHJG_RS05890	COG3631	Ketosteroid isomerase-related protein
SHJG_RS05905	COG1309	transcriptional regulator
SHJG_RS05935	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS05940	COG0583	DNA-binding transcription factor activity
SHJG_RS05945	COG1309	transcriptional regulator
SHJG_RS05950	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS05955	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS05985	COG1309	transcriptional regulator
SHJG_RS05995	COG3903	Transcriptional regulator
SHJG_RS05995	COG3629	intracellular signal transduction
SHJG_RS06000	COG0596	Alpha beta hydrolase
SHJG_RS06010	COG0596	Alpha beta hydrolase
SHJG_RS06030	COG0667	Aldo Keto reductase
SHJG_RS06045	COG1309	transcriptional regulator
SHJG_RS06065	COG0402	S-adenosylhomocysteine deaminase activity
SHJG_RS06070	COG1733	regulation of RNA biosynthetic process
SHJG_RS06075	COG2197	response regulator
SHJG_RS06080	COG4585	Histidine kinase
SHJG_RS06090	COG1136	(ABC) transporter
SHJG_RS06090	COG0577	efflux transmembrane transporter activity
SHJG_RS06130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJG_RS06145	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SHJG_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS06175	COG2867	negative regulation of translational initiation
SHJG_RS06185	COG0477	Major facilitator Superfamily
SHJG_RS06190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJG_RS06200	COG2867	negative regulation of translational initiation
SHJG_RS06250	COG2814	Major facilitator Superfamily
SHJG_RS06265	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS06320	COG0596	Alpha beta hydrolase
SHJG_RS06375	COG1609	Transcriptional regulator
SHJG_RS06390	COG0179	Fumarylacetoacetate (FAA) hydrolase
SHJG_RS06395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJG_RS06400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJG_RS06445	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SHJG_RS06450	COG3844	kynureninase activity
SHJG_RS06460	COG3483	tryptophan 2,3-dioxygenase activity
SHJG_RS06465	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS06470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SHJG_RS06475	COG2151	metal-sulfur cluster biosynthetic enzyme
SHJG_RS06480	COG3396	Phenylacetate-CoA oxygenase
SHJG_RS06490	COG3396	Phenylacetate-CoA oxygenase
SHJG_RS06515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS06565	COG3479	Phenolic acid decarboxylase
SHJG_RS06575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SHJG_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS06600	COG2186	Transcriptional regulator
SHJG_RS06610	COG4948	Mandelate Racemase Muconate Lactonizing
SHJG_RS06620	COG1175	transmembrane transport
SHJG_RS06625	COG0395	ABC-type sugar transport system, permease component
SHJG_RS06650	COG0596	Alpha beta hydrolase
SHJG_RS06655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SHJG_RS06655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SHJG_RS06675	COG3548	integral membrane protein
SHJG_RS06695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SHJG_RS06695	COG1017	nitric oxide dioxygenase activity
SHJG_RS06740	COG0667	Aldo Keto reductase
SHJG_RS06745	COG2207	Transcriptional regulator
SHJG_RS06770	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SHJG_RS06785	COG1309	transcriptional regulator
SHJG_RS06800	COG0673	inositol 2-dehydrogenase activity
SHJG_RS06805	COG1309	transcriptional regulator
SHJG_RS06815	COG2124	cytochrome p450
SHJG_RS06865	COG2175	clavaminate synthase activity
SHJG_RS06870	COG0529	Catalyzes the synthesis of activated sulfate
SHJG_RS06870	COG2046	Belongs to the sulfate adenylyltransferase family
SHJG_RS06880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SHJG_RS06905	COG0601	transmembrane transport
SHJG_RS06915	COG0444	Belongs to the ABC transporter superfamily
SHJG_RS06935	COG0477	Major facilitator Superfamily
SHJG_RS06965	COG0300	oxidoreductase activity
SHJG_RS06980	COG0657	acetylesterase activity
SHJG_RS06990	COG2197	response regulator
SHJG_RS06995	COG4585	Histidine kinase
SHJG_RS07100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS07125	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS07140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJG_RS07140	COG3320	Male sterility
SHJG_RS07160	COG2175	clavaminate synthase activity
SHJG_RS07165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SHJG_RS07195	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SHJG_RS07215	COG2963	transposase activity
SHJG_RS07220	COG2801	Transposase and inactivated derivatives
SHJG_RS07250	COG3293	Transposase
SHJG_RS07275	COG2207	Transcriptional regulator
SHJG_RS07290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SHJG_RS07295	COG4977	sequence-specific DNA binding
SHJG_RS07355	COG2801	Transposase and inactivated derivatives
SHJG_RS07425	COG0747	negative chemotaxis
SHJG_RS07445	COG2801	Transposase and inactivated derivatives
SHJG_RS07460	COG1278	Cold shock
SHJG_RS07470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJG_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS07535	COG0823	Involved in the tonB-independent uptake of proteins
SHJG_RS07535	COG1506	peptidase
SHJG_RS07590	COG2801	Transposase and inactivated derivatives
SHJG_RS07590	COG3415	Transposase
SHJG_RS07615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SHJG_RS07630	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS07630	COG1454	alcohol dehydrogenase
SHJG_RS07655	COG0531	amino acid
SHJG_RS07660	COG2235	arginine
SHJG_RS07670	COG0549	Belongs to the carbamate kinase family
SHJG_RS07700	COG2326	polyphosphate kinase activity
SHJG_RS07715	COG4191	Histidine kinase
SHJG_RS07730	COG0589	response to stress
SHJG_RS07735	COG0574	Belongs to the PEP-utilizing enzyme family
SHJG_RS07735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJG_RS07740	COG0574	Belongs to the PEP-utilizing enzyme family
SHJG_RS07740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJG_RS07745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJG_RS07745	COG0574	Belongs to the PEP-utilizing enzyme family
SHJG_RS07750	COG0574	Belongs to the PEP-utilizing enzyme family
SHJG_RS07750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJG_RS07760	COG0659	secondary active sulfate transmembrane transporter activity
SHJG_RS07780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJG_RS07795	COG0009	L-threonylcarbamoyladenylate synthase
SHJG_RS07800	COG4716	Myosin-crossreactive antigen
SHJG_RS07875	COG2133	pyrroloquinoline quinone binding
SHJG_RS07885	COG1278	Cold shock
SHJG_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS07920	COG0604	alcohol dehydrogenase
SHJG_RS07920	COG3321	synthase
SHJG_RS07925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJG_RS07980	COG2207	Transcriptional regulator
SHJG_RS08070	COG0583	DNA-binding transcription factor activity
SHJG_RS08085	COG3293	Transposase
SHJG_RS08280	COG1404	Belongs to the peptidase S8 family
SHJG_RS08345	COG1231	oxidoreductase activity
SHJG_RS08400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SHJG_RS08410	COG4221	oxidoreductase activity
SHJG_RS08500	COG1486	melibiose metabolic process
SHJG_RS08505	COG1349	DNA-binding transcription factor activity
SHJG_RS08510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJG_RS08520	COG1175	transmembrane transport
SHJG_RS08530	COG3250	beta-galactosidase activity
SHJG_RS08575	COG3340	Belongs to the peptidase S51 family
SHJG_RS08610	COG4865	methylaspartate mutase activity
SHJG_RS08615	COG0017	Asparaginyl-tRNA synthetase
SHJG_RS08625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJG_RS08630	COG2423	ornithine cyclodeaminase activity
SHJG_RS08660	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SHJG_RS08670	COG0142	geranyltranstransferase activity
SHJG_RS08690	COG0789	Transcriptional regulator
SHJG_RS08700	COG2409	Drug exporters of the RND superfamily
SHJG_RS08705	COG1846	Transcriptional regulator
SHJG_RS08710	COG1335	isochorismatase
SHJG_RS08775	COG0583	DNA-binding transcription factor activity
SHJG_RS08785	COG0584	glycerophosphoryl diester phosphodiesterase
SHJG_RS08820	COG3903	Transcriptional regulator
SHJG_RS08820	COG3629	intracellular signal transduction
SHJG_RS08835	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS08845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJG_RS08850	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SHJG_RS08855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJG_RS08860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJG_RS08875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SHJG_RS08975	COG1733	regulation of RNA biosynthetic process
SHJG_RS08980	COG0702	epimerase
SHJG_RS08990	COG0028	Belongs to the TPP enzyme family
SHJG_RS08995	COG3527	Alpha-acetolactate decarboxylase
SHJG_RS09005	COG3842	ATPase activity
SHJG_RS09015	COG1176	ABC-type spermidine putrescine transport system, permease component I
SHJG_RS09020	COG1177	transmembrane transport
SHJG_RS09030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJG_RS09040	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS09045	COG2814	Major facilitator Superfamily
SHJG_RS09080	COG0583	DNA-binding transcription factor activity
SHJG_RS09085	COG0183	Belongs to the thiolase family
SHJG_RS09095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SHJG_RS09100	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJG_RS09120	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS09130	COG0586	Pfam SNARE associated Golgi protein
SHJG_RS09140	COG0431	NADPH-dependent FMN reductase
SHJG_RS09145	COG0583	DNA-binding transcription factor activity
SHJG_RS09150	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS09180	COG1846	Transcriptional regulator
SHJG_RS09185	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SHJG_RS09190	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS09200	COG1309	transcriptional regulator
SHJG_RS09215	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS09220	COG4689	acetoacetate decarboxylase
SHJG_RS09235	COG0174	glutamine synthetase
SHJG_RS09260	COG0596	Alpha beta hydrolase
SHJG_RS09295	COG1129	ABC transporter
SHJG_RS09300	COG4211	Belongs to the binding-protein-dependent transport system permease family
SHJG_RS09305	COG1172	Belongs to the binding-protein-dependent transport system permease family
SHJG_RS09310	COG4948	Mandelate Racemase Muconate Lactonizing
SHJG_RS09320	COG1846	Transcriptional regulator
SHJG_RS09320	COG1940	carbohydrate kinase activity
SHJG_RS09325	COG3345	alpha-galactosidase
SHJG_RS09355	COG1063	alcohol dehydrogenase
SHJG_RS09385	COG1063	alcohol dehydrogenase
SHJG_RS09390	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SHJG_RS09405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJG_RS09415	COG4977	sequence-specific DNA binding
SHJG_RS09430	COG2175	clavaminate synthase activity
SHJG_RS09440	COG4521	taurine ABC transporter
SHJG_RS09445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SHJG_RS09450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SHJG_RS09470	COG2226	methyltransferase
SHJG_RS09495	COG0655	NAD(P)H dehydrogenase (quinone) activity
SHJG_RS09500	COG2226	methyltransferase
SHJG_RS09505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SHJG_RS09515	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SHJG_RS09570	COG2234	aminopeptidase activity
SHJG_RS09585	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SHJG_RS09600	COG1404	Belongs to the peptidase S8 family
SHJG_RS09620	COG0477	Major facilitator Superfamily
SHJG_RS09625	COG3250	beta-galactosidase activity
SHJG_RS09635	COG0583	DNA-binding transcription factor activity
SHJG_RS09645	COG0714	Associated with various cellular activities
SHJG_RS09680	COG0596	Alpha beta hydrolase
SHJG_RS09690	COG2267	carboxylic ester hydrolase activity
SHJG_RS09695	COG2508	Transcriptional regulator
SHJG_RS09720	COG2815	serine threonine protein kinase
SHJG_RS09720	COG0515	serine threonine protein kinase
SHJG_RS09775	COG2318	DinB family
SHJG_RS09780	COG0583	DNA-binding transcription factor activity
SHJG_RS09805	COG3973	AAA domain
SHJG_RS09815	COG3321	synthase
SHJG_RS09815	COG0604	alcohol dehydrogenase
SHJG_RS09820	COG3321	synthase
SHJG_RS09820	COG0604	alcohol dehydrogenase
SHJG_RS09845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS09860	COG2267	carboxylic ester hydrolase activity
SHJG_RS09870	COG2124	cytochrome p450
SHJG_RS09880	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS09890	COG2197	response regulator
SHJG_RS09905	COG0577	efflux transmembrane transporter activity
SHJG_RS09905	COG1136	(ABC) transporter
SHJG_RS09915	COG0604	alcohol dehydrogenase
SHJG_RS09915	COG3321	synthase
SHJG_RS09945	COG4977	sequence-specific DNA binding
SHJG_RS09990	COG3903	Transcriptional regulator
SHJG_RS09990	COG3629	intracellular signal transduction
SHJG_RS09995	COG3896	Chloramphenicol phosphotransferase-like protein
SHJG_RS10010	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS10015	COG1295	ribonuclease BN
SHJG_RS10035	COG0701	Predicted permease
SHJG_RS10050	COG1482	cell wall glycoprotein biosynthetic process
SHJG_RS10085	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SHJG_RS10110	COG0375	protein maturation
SHJG_RS10125	COG0298	carbon dioxide binding
SHJG_RS10130	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SHJG_RS10140	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SHJG_RS10145	COG1024	Enoyl-CoA hydratase
SHJG_RS10145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SHJG_RS10200	COG0640	Transcriptional regulator
SHJG_RS10265	COG0667	Aldo Keto reductase
SHJG_RS10285	COG0586	Pfam SNARE associated Golgi protein
SHJG_RS10300	COG3850	Histidine kinase
SHJG_RS10300	COG3437	response regulator, receiver
SHJG_RS10300	COG2205	protein histidine kinase activity
SHJG_RS10300	COG4999	Histidine kinase
SHJG_RS10320	COG0437	4 iron, 4 sulfur cluster binding
SHJG_RS10340	COG0243	molybdopterin cofactor binding
SHJG_RS10340	COG3383	formate dehydrogenase (NAD+) activity
SHJG_RS10345	COG0243	molybdopterin cofactor binding
SHJG_RS10345	COG3383	formate dehydrogenase (NAD+) activity
SHJG_RS10350	COG0709	Synthesizes selenophosphate from selenide and ATP
SHJG_RS10355	COG0546	phosphoglycolate phosphatase activity
SHJG_RS10375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SHJG_RS10415	COG2267	carboxylic ester hydrolase activity
SHJG_RS10440	COG0583	DNA-binding transcription factor activity
SHJG_RS10530	COG0477	Major facilitator Superfamily
SHJG_RS10540	COG0009	L-threonylcarbamoyladenylate synthase
SHJG_RS10585	COG1621	beta-fructofuranosidase activity
SHJG_RS10595	COG1175	transmembrane transport
SHJG_RS10600	COG0395	ABC-type sugar transport system, permease component
SHJG_RS10605	COG1621	beta-fructofuranosidase activity
SHJG_RS10610	COG1609	Transcriptional regulator
SHJG_RS10615	COG0656	L-ascorbic acid biosynthetic process
SHJG_RS10625	COG0667	Aldo Keto reductase
SHJG_RS10675	COG1414	Transcriptional regulator
SHJG_RS10680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SHJG_RS10695	COG0181	hydroxymethylbilane synthase activity
SHJG_RS10705	COG0842	Transport permease protein
SHJG_RS10715	COG1846	Transcriptional regulator
SHJG_RS10750	COG0366	Alpha amylase catalytic
SHJG_RS10765	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SHJG_RS10770	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SHJG_RS10790	COG1252	NADH dehydrogenase
SHJG_RS10850	COG5002	protein histidine kinase activity
SHJG_RS10890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJG_RS10900	COG0589	response to stress
SHJG_RS10935	COG3345	alpha-galactosidase
SHJG_RS10940	COG1846	Transcriptional regulator
SHJG_RS10940	COG1940	carbohydrate kinase activity
SHJG_RS10970	COG3485	protocatechuate 3,4-dioxygenase
SHJG_RS10995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJG_RS10995	COG0515	serine threonine protein kinase
SHJG_RS11000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS11010	COG3647	Membrane
SHJG_RS11045	COG0328	RNA-DNA hybrid ribonuclease activity
SHJG_RS11065	COG1396	sequence-specific DNA binding
SHJG_RS11070	COG1191	sigma factor activity
SHJG_RS11090	COG0667	Aldo Keto reductase
SHJG_RS11095	COG0583	DNA-binding transcription factor activity
SHJG_RS11105	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJG_RS11110	COG0346	lactoylglutathione lyase activity
SHJG_RS11125	COG0667	Aldo Keto reductase
SHJG_RS11135	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS11160	COG0431	NADPH-dependent FMN reductase
SHJG_RS11170	COG0702	epimerase
SHJG_RS11195	COG3293	Transposase
SHJG_RS11200	COG0531	amino acid
SHJG_RS11205	COG1940	carbohydrate kinase activity
SHJG_RS11210	COG3250	beta-galactosidase activity
SHJG_RS11265	COG0367	asparagine synthase
SHJG_RS11280	COG0673	inositol 2-dehydrogenase activity
SHJG_RS11300	COG0510	thiamine kinase activity
SHJG_RS11335	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS11340	COG0596	Alpha beta hydrolase
SHJG_RS11355	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS11360	COG2070	2-Nitropropane dioxygenase
SHJG_RS11365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJG_RS11395	COG0542	response to heat
SHJG_RS11410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHJG_RS11415	COG0443	Heat shock 70 kDa protein
SHJG_RS11425	COG0047	phosphoribosylformylglycinamidine synthase activity
SHJG_RS11435	COG0656	L-ascorbic acid biosynthetic process
SHJG_RS11470	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS11490	COG2801	Transposase and inactivated derivatives
SHJG_RS11490	COG3415	Transposase
SHJG_RS11525	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SHJG_RS11525	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SHJG_RS11530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SHJG_RS11535	COG0297	glycogen (starch) synthase activity
SHJG_RS11550	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SHJG_RS11560	COG2192	nodulation
SHJG_RS11565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SHJG_RS11585	COG2124	cytochrome p450
SHJG_RS11605	COG2376	Dihydroxyacetone kinase
SHJG_RS11610	COG1461	Dihydroxyacetone kinase
SHJG_RS11640	COG1902	pentaerythritol trinitrate reductase activity
SHJG_RS11640	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJG_RS11675	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJG_RS11695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SHJG_RS11710	COG3458	cephalosporin-C deacetylase activity
SHJG_RS11715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJG_RS11720	COG2188	Transcriptional regulator
SHJG_RS11725	COG2226	methyltransferase
SHJG_RS11755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SHJG_RS11770	COG2066	Belongs to the glutaminase family
SHJG_RS11785	COG1113	amino acid transport
SHJG_RS11790	COG2186	Transcriptional regulator
SHJG_RS11795	COG1968	undecaprenyl-diphosphatase activity
SHJG_RS11825	COG1175	transmembrane transport
SHJG_RS11830	COG0395	ABC-type sugar transport system, permease component
SHJG_RS11845	COG0346	lactoylglutathione lyase activity
SHJG_RS11855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SHJG_RS11895	COG2340	Cysteine-rich secretory protein family
SHJG_RS11900	COG1733	regulation of RNA biosynthetic process
SHJG_RS11915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SHJG_RS11945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJG_RS11955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SHJG_RS12005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SHJG_RS12015	COG2124	cytochrome p450
SHJG_RS12035	COG2814	Major facilitator Superfamily
SHJG_RS12040	COG3548	integral membrane protein
SHJG_RS12070	COG4977	sequence-specific DNA binding
SHJG_RS12070	COG1917	Cupin 2, conserved barrel domain protein
SHJG_RS12075	COG2814	Major facilitator Superfamily
SHJG_RS12090	COG3903	Transcriptional regulator
SHJG_RS12090	COG3629	intracellular signal transduction
SHJG_RS12100	COG0805	protein transport
SHJG_RS12155	COG0561	phosphatase activity
SHJG_RS12165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS12185	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJG_RS12185	COG2172	sigma factor antagonist activity
SHJG_RS12185	COG2208	phosphoserine phosphatase activity
SHJG_RS12205	COG3209	COG3209 Rhs family protein
SHJG_RS12245	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SHJG_RS12250	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SHJG_RS12255	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SHJG_RS12290	COG2197	response regulator
SHJG_RS12305	COG0464	growth
SHJG_RS12405	COG1971	Probably functions as a manganese efflux pump
SHJG_RS12410	COG0535	radical SAM domain protein
SHJG_RS12440	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SHJG_RS12445	COG3284	Transcriptional regulator
SHJG_RS12450	COG0563	adenylate kinase activity
SHJG_RS12460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJG_RS12490	COG0535	radical SAM domain protein
SHJG_RS12520	COG2197	response regulator
SHJG_RS12525	COG4585	Histidine kinase
SHJG_RS12540	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS12555	COG0596	Alpha beta hydrolase
SHJG_RS12555	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJG_RS12560	COG0022	dehydrogenase e1 component
SHJG_RS12565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SHJG_RS12570	COG3199	ATP-NAD kinase
SHJG_RS12575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SHJG_RS12580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SHJG_RS12590	COG1063	alcohol dehydrogenase
SHJG_RS12600	COG0589	response to stress
SHJG_RS12605	COG2706	6-phosphogluconolactonase activity
SHJG_RS12615	COG3387	PFAM Glycoside hydrolase 15-related
SHJG_RS12620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SHJG_RS12625	COG3265	gluconokinase activity
SHJG_RS12640	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS12665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SHJG_RS12670	COG1215	transferase activity, transferring glycosyl groups
SHJG_RS12705	COG1349	DNA-binding transcription factor activity
SHJG_RS12715	COG1024	Enoyl-CoA hydratase
SHJG_RS12785	COG1619	proteins homologs of microcin C7 resistance protein MccF
SHJG_RS12790	COG1940	carbohydrate kinase activity
SHJG_RS12800	COG2813	Specifically methylates the guanine in position
SHJG_RS12805	COG0191	fructose-bisphosphate aldolase activity
SHJG_RS12810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SHJG_RS12815	COG1349	DNA-binding transcription factor activity
SHJG_RS12825	COG3579	cysteine-type endopeptidase activity
SHJG_RS12850	COG2197	response regulator
SHJG_RS12855	COG4585	Histidine kinase
SHJG_RS12875	COG0445	tRNA wobble uridine modification
SHJG_RS12885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJG_RS12890	COG1660	Displays ATPase and GTPase activities
SHJG_RS12900	COG3345	alpha-galactosidase
SHJG_RS12920	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SHJG_RS12965	COG0584	glycerophosphoryl diester phosphodiesterase
SHJG_RS12995	COG2124	cytochrome p450
SHJG_RS13025	COG0671	phosphoesterase, PA-phosphatase related
SHJG_RS13050	COG2233	PERMEase
SHJG_RS13055	COG0640	Transcriptional regulator
SHJG_RS13060	COG1902	pentaerythritol trinitrate reductase activity
SHJG_RS13065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SHJG_RS13080	COG3509	depolymerase
SHJG_RS13095	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS13115	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SHJG_RS13140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SHJG_RS13145	COG0477	Major facilitator Superfamily
SHJG_RS13165	COG0432	Pfam Uncharacterised protein family UPF0047
SHJG_RS13170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SHJG_RS13175	COG1116	anion transmembrane transporter activity
SHJG_RS13185	COG2072	flavoprotein involved in K transport
SHJG_RS13190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SHJG_RS13195	COG1132	(ABC) transporter
SHJG_RS13200	COG1846	Transcriptional regulator
SHJG_RS13225	COG1132	(ABC) transporter
SHJG_RS13235	COG0254	rRNA binding
SHJG_RS13250	COG1946	Acyl-CoA thioesterase
SHJG_RS13260	COG2018	Roadblock/LC7 domain
SHJG_RS13285	COG3547	Transposase (IS116 IS110 IS902 family)
SHJG_RS13340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SHJG_RS13365	COG1940	carbohydrate kinase activity
SHJG_RS13365	COG1846	Transcriptional regulator
SHJG_RS13370	COG1113	amino acid transport
SHJG_RS13390	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS13405	COG0586	Pfam SNARE associated Golgi protein
SHJG_RS13440	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS13445	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS13460	COG3118	belongs to the thioredoxin family
SHJG_RS13460	COG0492	ferredoxin-NADP+ reductase activity
SHJG_RS13465	COG1793	dna ligase
SHJG_RS13485	COG3424	synthase
SHJG_RS13490	COG2124	cytochrome p450
SHJG_RS13500	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS13510	COG0242	peptide deformylase activity
SHJG_RS13520	COG3442	glutamine amidotransferase
SHJG_RS13525	COG0205	6-phosphofructokinase activity
SHJG_RS13540	COG1522	sequence-specific DNA binding
SHJG_RS13545	COG1834	amidinotransferase
SHJG_RS13550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SHJG_RS13570	COG0204	Acyl-transferase
SHJG_RS13585	COG0829	nickel cation binding
SHJG_RS13590	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SHJG_RS13595	COG0830	nickel cation binding
SHJG_RS13600	COG0804	urea catabolic process
SHJG_RS13605	COG0832	Belongs to the urease beta subunit family
SHJG_RS13610	COG0831	urea catabolic process
SHJG_RS13620	COG0740	serine-type endopeptidase activity
SHJG_RS13650	COG0156	8-amino-7-oxononanoate synthase activity
SHJG_RS13655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SHJG_RS13660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SHJG_RS13665	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SHJG_RS13670	COG2226	methyltransferase
SHJG_RS13690	COG0456	acetyltransferase
SHJG_RS13710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SHJG_RS13715	COG3663	DNA glycosylase
SHJG_RS13735	COG4585	Histidine kinase
SHJG_RS13740	COG2197	response regulator
SHJG_RS13745	COG1940	carbohydrate kinase activity
SHJG_RS13755	COG1595	DNA-templated transcription, initiation
SHJG_RS13780	COG0626	cystathionine gamma-synthase activity
SHJG_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS13820	COG4585	Histidine kinase
SHJG_RS13845	COG1522	sequence-specific DNA binding
SHJG_RS13855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SHJG_RS13860	COG0419	ATPase involved in DNA repair
SHJG_RS13865	COG0420	3'-5' exonuclease activity
SHJG_RS13870	COG1739	Uncharacterized protein family UPF0029
SHJG_RS13885	COG1832	CoA-binding protein
SHJG_RS13900	COG0640	Transcriptional regulator
SHJG_RS13965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SHJG_RS13980	COG0183	Belongs to the thiolase family
SHJG_RS13990	COG1968	undecaprenyl-diphosphatase activity
SHJG_RS14005	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SHJG_RS14020	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SHJG_RS14025	COG0747	negative chemotaxis
SHJG_RS14070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SHJG_RS14115	COG0697	spore germination
SHJG_RS14180	COG3507	Belongs to the glycosyl hydrolase 43 family
SHJG_RS14205	COG0725	ABC transporter, periplasmic molybdate-binding protein
SHJG_RS14225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SHJG_RS14225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SHJG_RS14235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SHJG_RS14255	COG1716	ATPase activity
SHJG_RS14275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SHJG_RS14305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJG_RS14315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJG_RS14350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SHJG_RS14355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SHJG_RS14375	COG2018	Roadblock/LC7 domain
SHJG_RS14390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJG_RS14395	COG2146	nitrite reductase [NAD(P)H] activity
SHJG_RS14400	COG1414	Transcriptional regulator
SHJG_RS14420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJG_RS14425	COG4638	Rieske (2fe-2S)
SHJG_RS14430	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS14465	COG2814	Major facilitator Superfamily
SHJG_RS14470	COG4336	lyase activity
SHJG_RS14475	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SHJG_RS14480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SHJG_RS14485	COG1984	allophanate hydrolase subunit 2
SHJG_RS14495	COG0438	transferase activity, transferring glycosyl groups
SHJG_RS14530	COG2364	Membrane
SHJG_RS14540	COG2270	Major facilitator Superfamily
SHJG_RS14550	COG3030	protein affecting phage T7 exclusion by the F plasmid
SHJG_RS14555	COG0463	Glycosyl transferase, family 2
SHJG_RS14575	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS14630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SHJG_RS14635	COG0140	phosphoribosyl-ATP diphosphatase activity
SHJG_RS14640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SHJG_RS14645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SHJG_RS14645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SHJG_RS14650	COG3201	nicotinamide mononucleotide transporter
SHJG_RS14665	COG1940	carbohydrate kinase activity
SHJG_RS14665	COG1846	Transcriptional regulator
SHJG_RS14670	COG0738	Major facilitator superfamily
SHJG_RS14685	COG2233	PERMEase
SHJG_RS14700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SHJG_RS14710	COG0531	amino acid
SHJG_RS14735	COG2390	Transcriptional regulator
SHJG_RS14740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SHJG_RS14750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SHJG_RS14765	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SHJG_RS14780	COG0194	GDP metabolic process
SHJG_RS14790	COG0284	orotidine-5'-phosphate decarboxylase activity
SHJG_RS14795	COG0167	dihydroorotate dehydrogenase activity
SHJG_RS14800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SHJG_RS14805	COG0505	Belongs to the CarA family
SHJG_RS14815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SHJG_RS14820	COG0540	Belongs to the ATCase OTCase family
SHJG_RS14825	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SHJG_RS14835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SHJG_RS14840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SHJG_RS14845	COG0006	proline dipeptidase activity
SHJG_RS14855	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SHJG_RS14860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SHJG_RS14865	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SHJG_RS14870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SHJG_RS14880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SHJG_RS14885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SHJG_RS14905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SHJG_RS14920	COG0124	histidyl-tRNA synthetase
SHJG_RS14930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SHJG_RS14935	COG1196	nuclear chromosome segregation
SHJG_RS14940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SHJG_RS14945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SHJG_RS14950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SHJG_RS14955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SHJG_RS14965	COG2255	four-way junction helicase activity
SHJG_RS14970	COG0632	four-way junction helicase activity
SHJG_RS14975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SHJG_RS14980	COG0217	transcriptional regulatory protein
SHJG_RS14985	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SHJG_RS14990	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SHJG_RS15000	COG0438	transferase activity, transferring glycosyl groups
SHJG_RS15005	COG1560	Kdo2-lipid A biosynthetic process
SHJG_RS15010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SHJG_RS15030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SHJG_RS15045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SHJG_RS15100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SHJG_RS15155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SHJG_RS15155	COG1648	precorrin-2 dehydrogenase activity
SHJG_RS15160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SHJG_RS15185	COG1464	Belongs to the NlpA lipoprotein family
SHJG_RS15190	COG2011	ABC-type metal ion transport system permease component
SHJG_RS15195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SHJG_RS15225	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS15225	COG0204	Acyl-transferase
SHJG_RS15230	COG2132	Multicopper oxidase
SHJG_RS15235	COG0477	Major facilitator Superfamily
SHJG_RS15250	COG0165	Argininosuccinate lyase
SHJG_RS15255	COG0137	argininosuccinate synthase activity
SHJG_RS15275	COG2205	protein histidine kinase activity
SHJG_RS15280	COG0745	RESPONSE REGULATOR receiver
SHJG_RS15320	COG1438	arginine binding
SHJG_RS15325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SHJG_RS15330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SHJG_RS15335	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SHJG_RS15340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SHJG_RS15350	COG0463	Glycosyl transferase, family 2
SHJG_RS15405	COG1649	PFAM Uncharacterised BCR, COG1649
SHJG_RS15435	COG0072	phenylalanine-tRNA ligase activity
SHJG_RS15435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SHJG_RS15440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SHJG_RS15445	COG5002	protein histidine kinase activity
SHJG_RS15450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SHJG_RS15455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SHJG_RS15460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SHJG_RS15465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SHJG_RS15510	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS15515	COG0174	glutamine synthetase
SHJG_RS15525	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SHJG_RS15550	COG4176	ABC-type proline glycine betaine transport system permease component
SHJG_RS15555	COG0517	IMP dehydrogenase activity
SHJG_RS15555	COG4175	Glycine betaine
SHJG_RS15560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SHJG_RS15575	COG0564	pseudouridine synthase activity
SHJG_RS15615	COG0805	protein transport
SHJG_RS15620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SHJG_RS15655	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SHJG_RS15665	COG1609	Transcriptional regulator
SHJG_RS15670	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SHJG_RS15675	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SHJG_RS15690	COG4122	O-methyltransferase activity
SHJG_RS15695	COG1222	aaa ATPase
SHJG_RS15715	COG0517	IMP dehydrogenase activity
SHJG_RS15715	COG1994	Peptidase M50
SHJG_RS15725	COG2197	response regulator
SHJG_RS15730	COG0747	negative chemotaxis
SHJG_RS15740	COG1410	methionine synthase
SHJG_RS15740	COG0646	methionine synthase
SHJG_RS15745	COG1414	Transcriptional regulator
SHJG_RS15750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SHJG_RS15755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SHJG_RS15760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SHJG_RS15765	COG2186	Transcriptional regulator
SHJG_RS15775	COG0215	cysteine-tRNA ligase activity
SHJG_RS15795	COG0598	Magnesium transport protein CorA
SHJG_RS15805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS15810	COG0667	Aldo Keto reductase
SHJG_RS15835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJG_RS15845	COG1796	DNA polymerase
SHJG_RS15845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SHJG_RS15865	COG3012	SEC-C Motif Domain Protein
SHJG_RS15870	COG2186	Transcriptional regulator
SHJG_RS15875	COG3265	gluconokinase activity
SHJG_RS15885	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS15890	COG1063	alcohol dehydrogenase
SHJG_RS15915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SHJG_RS15920	COG2149	membrane
SHJG_RS15950	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS15960	COG3876	Protein conserved in bacteria
SHJG_RS15995	COG0789	Transcriptional regulator
SHJG_RS16015	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS16025	COG0640	Transcriptional regulator
SHJG_RS16055	COG2851	Citrate transporter
SHJG_RS16060	COG0243	molybdopterin cofactor binding
SHJG_RS16065	COG1309	transcriptional regulator
SHJG_RS16075	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SHJG_RS16080	COG2188	Transcriptional regulator
SHJG_RS16120	COG1595	DNA-templated transcription, initiation
SHJG_RS16140	COG2755	lipolytic protein G-D-S-L family
SHJG_RS16155	COG1725	Transcriptional regulator
SHJG_RS16180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SHJG_RS16185	COG0587	DNA-directed DNA polymerase activity
SHJG_RS16210	COG1126	abc transporter atp-binding protein
SHJG_RS16220	COG0765	amino acid transport
SHJG_RS16250	COG1799	cell septum assembly
SHJG_RS16255	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS16260	COG0477	Major facilitator Superfamily
SHJG_RS16270	COG0671	phosphoesterase, PA-phosphatase related
SHJG_RS16280	COG1652	LysM domain
SHJG_RS16295	COG1160	GTP binding
SHJG_RS16305	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SHJG_RS16330	COG3541	Predicted nucleotidyltransferase
SHJG_RS16335	COG1397	ADP-ribosylglycohydrolase
SHJG_RS16340	COG1187	pseudouridine synthase activity
SHJG_RS16345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SHJG_RS16350	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SHJG_RS16365	COG0686	Belongs to the AlaDH PNT family
SHJG_RS16375	COG0494	nUDIX hydrolase
SHJG_RS16380	COG0504	CTP synthase activity
SHJG_RS16385	COG3387	PFAM Glycoside hydrolase 15-related
SHJG_RS16400	COG0297	glycogen (starch) synthase activity
SHJG_RS16410	COG0497	DNA recombination
SHJG_RS16415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SHJG_RS16435	COG1120	ATPase activity
SHJG_RS16440	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SHJG_RS16445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SHJG_RS16450	COG0647	UMP catabolic process
SHJG_RS16485	COG2094	Belongs to the DNA glycosylase MPG family
SHJG_RS16495	COG1881	PFAM PEBP family protein
SHJG_RS16515	COG1119	ATPase activity
SHJG_RS16535	COG2197	response regulator
SHJG_RS16540	COG3850	Histidine kinase
SHJG_RS16560	COG1131	(ABC) transporter
SHJG_RS16560	COG0842	Transport permease protein
SHJG_RS16560	COG1716	ATPase activity
SHJG_RS16565	COG0560	Phosphoserine phosphatase
SHJG_RS16565	COG3830	Belongs to the UPF0237 family
SHJG_RS16585	COG2186	Transcriptional regulator
SHJG_RS16615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SHJG_RS16635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SHJG_RS16640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJG_RS16655	COG1404	Belongs to the peptidase S8 family
SHJG_RS16660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJG_RS16665	COG1063	alcohol dehydrogenase
SHJG_RS16680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SHJG_RS16695	COG3387	PFAM Glycoside hydrolase 15-related
SHJG_RS16745	COG0488	(ABC) transporter
SHJG_RS16765	COG2267	carboxylic ester hydrolase activity
SHJG_RS16770	COG0235	Class ii aldolase
SHJG_RS16790	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SHJG_RS16795	COG1492	cobalamin metabolic process
SHJG_RS16815	COG1797	cobyrinic acid a,c-diamide synthase activity
SHJG_RS16850	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
SHJG_RS16875	COG0765	amino acid transport
SHJG_RS16880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJG_RS16885	COG1104	cysteine desulfurase activity
SHJG_RS16890	COG0456	acetyltransferase
SHJG_RS16895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SHJG_RS16900	COG1917	Cupin 2, conserved barrel domain protein
SHJG_RS16905	COG5285	phytanoyl-CoA dioxygenase
SHJG_RS16935	COG1414	Transcriptional regulator
SHJG_RS16950	COG2252	PERMEase
SHJG_RS16960	COG2186	Transcriptional regulator
SHJG_RS16995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJG_RS17000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SHJG_RS17005	COG1349	DNA-binding transcription factor activity
SHJG_RS17020	COG0395	ABC-type sugar transport system, permease component
SHJG_RS17025	COG1063	alcohol dehydrogenase
SHJG_RS17035	COG1309	transcriptional regulator
SHJG_RS17075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJG_RS17080	COG2171	N-acyltransferase activity
SHJG_RS17085	COG3226	Transcriptional regulator
SHJG_RS17090	COG2076	Multidrug Resistance protein
SHJG_RS17095	COG2151	metal-sulfur cluster biosynthetic enzyme
SHJG_RS17100	COG0822	iron-sulfur transferase activity
SHJG_RS17105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SHJG_RS17110	COG0396	ATPase activity
SHJG_RS17120	COG0719	Fe-S assembly protein
SHJG_RS17135	COG2746	aminoglycoside 3-N-acetyltransferase activity
SHJG_RS17140	COG1131	(ABC) transporter
SHJG_RS17150	COG1612	heme a metabolic process
SHJG_RS17170	COG0109	protoheme IX farnesyltransferase activity
SHJG_RS17180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SHJG_RS17195	COG0363	glucosamine-6-phosphate deaminase activity
SHJG_RS17200	COG0395	ABC-type sugar transport system, permease component
SHJG_RS17205	COG1175	transmembrane transport
SHJG_RS17210	COG1653	transport
SHJG_RS17215	COG0366	Alpha amylase catalytic
SHJG_RS17220	COG1653	transport
SHJG_RS17225	COG1695	Transcriptional regulator
SHJG_RS17230	COG1136	(ABC) transporter
SHJG_RS17240	COG0166	Belongs to the GPI family
SHJG_RS17255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SHJG_RS17260	COG0149	triose-phosphate isomerase activity
SHJG_RS17265	COG0126	phosphoglycerate kinase activity
SHJG_RS17270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SHJG_RS17280	COG1481	regulation of sporulation
SHJG_RS17285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SHJG_RS17290	COG1660	Displays ATPase and GTPase activities
SHJG_RS17295	COG0322	excinuclease ABC activity
SHJG_RS17310	COG1609	Transcriptional regulator
SHJG_RS17320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SHJG_RS17335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJG_RS17340	COG0765	amino acid transport
SHJG_RS17350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SHJG_RS17355	COG0477	Major facilitator Superfamily
SHJG_RS17360	COG0387	Pfam Sodium calcium exchanger
SHJG_RS17380	COG0556	nucleotide-excision repair
SHJG_RS17390	COG0584	glycerophosphoryl diester phosphodiesterase
SHJG_RS17395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SHJG_RS17405	COG2313	pseudouridylate synthase activity
SHJG_RS17410	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SHJG_RS17410	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SHJG_RS17415	COG2226	methyltransferase
SHJG_RS17420	COG0598	Magnesium transport protein CorA
SHJG_RS17445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJG_RS17450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SHJG_RS17480	COG1132	(ABC) transporter
SHJG_RS17515	COG1953	Uracil, thiamine, allantoin
SHJG_RS17520	COG1802	Transcriptional regulator
SHJG_RS17540	COG2226	methyltransferase
SHJG_RS17560	COG0237	dephospho-CoA kinase activity
SHJG_RS17575	COG0539	negative regulation of cytoplasmic translation
SHJG_RS17585	COG1643	Atp-dependent helicase
SHJG_RS17620	COG2050	protein possibly involved in aromatic compounds catabolism
SHJG_RS17680	COG0737	Belongs to the 5'-nucleotidase family
SHJG_RS17700	COG1605	Chorismate mutase
SHJG_RS17700	COG0287	Prephenate dehydrogenase
SHJG_RS17720	COG0183	Belongs to the thiolase family
SHJG_RS17725	COG1309	transcriptional regulator
SHJG_RS17735	COG2304	oxidoreductase activity
SHJG_RS17745	COG0069	glutamate synthase activity
SHJG_RS17745	COG0067	glutamate synthase
SHJG_RS17745	COG0070	glutamate synthase
SHJG_RS17755	COG1397	ADP-ribosylglycohydrolase
SHJG_RS17775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJG_RS17780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJG_RS17785	COG2301	Belongs to the HpcH HpaI aldolase family
SHJG_RS17790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SHJG_RS17800	COG0159	tryptophan synthase activity
SHJG_RS17805	COG0133	tryptophan synthase activity
SHJG_RS17810	COG0134	indole-3-glycerol-phosphate synthase activity
SHJG_RS17830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SHJG_RS17835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SHJG_RS17860	COG0107	imidazoleglycerol-phosphate synthase activity
SHJG_RS17865	COG0251	oxidation-reduction process
SHJG_RS17870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SHJG_RS17875	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SHJG_RS17885	COG0131	Imidazoleglycerol-phosphate dehydratase
SHJG_RS17890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJG_RS17895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SHJG_RS17915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SHJG_RS17935	COG1432	Conserved Protein
SHJG_RS17940	COG0587	DNA-directed DNA polymerase activity
SHJG_RS17995	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SHJG_RS18005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SHJG_RS18010	COG3599	regulation of cell shape
SHJG_RS18020	COG1799	cell septum assembly
SHJG_RS18030	COG1496	oxidoreductase activity
SHJG_RS18035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SHJG_RS18045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SHJG_RS18055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SHJG_RS18060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SHJG_RS18065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SHJG_RS18070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SHJG_RS18075	COG0768	penicillin binding
SHJG_RS18085	COG0275	rRNA processing
SHJG_RS18095	COG0714	Associated with various cellular activities
SHJG_RS18115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SHJG_RS18125	COG1126	abc transporter atp-binding protein
SHJG_RS18135	COG1309	transcriptional regulator
SHJG_RS18160	COG0352	thiamine-phosphate diphosphorylase activity
SHJG_RS18180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJG_RS18180	COG2022	thiamine diphosphate biosynthetic process
SHJG_RS18190	COG2022	thiamine diphosphate biosynthetic process
SHJG_RS18195	COG0515	serine threonine protein kinase
SHJG_RS18195	COG2815	serine threonine protein kinase
SHJG_RS18200	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SHJG_RS18210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SHJG_RS18215	COG2193	ferroxidase activity
SHJG_RS18225	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SHJG_RS18235	COG0205	6-phosphofructokinase activity
SHJG_RS18270	COG1940	carbohydrate kinase activity
SHJG_RS18280	COG0003	Pfam Anion-transporting ATPase
SHJG_RS18355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SHJG_RS18360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SHJG_RS18365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SHJG_RS18370	COG0723	plastoquinol--plastocyanin reductase activity
SHJG_RS18375	COG2010	Cytochrome c
SHJG_RS18380	COG1845	cytochrome c oxidase, subunit III
SHJG_RS18390	COG1376	ErfK ybiS ycfS ynhG family protein
SHJG_RS18400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJG_RS18405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SHJG_RS18415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJG_RS18435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SHJG_RS18440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SHJG_RS18445	COG2197	response regulator
SHJG_RS18450	COG4585	Histidine kinase
SHJG_RS18475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SHJG_RS18495	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SHJG_RS18500	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SHJG_RS18500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SHJG_RS18515	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SHJG_RS18520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SHJG_RS18525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SHJG_RS18540	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SHJG_RS18565	COG2801	Transposase and inactivated derivatives
SHJG_RS18565	COG3415	Transposase
SHJG_RS18590	COG0321	lipoyl(octanoyl) transferase activity
SHJG_RS18595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SHJG_RS18625	COG2867	negative regulation of translational initiation
SHJG_RS18630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJG_RS18635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJG_RS18645	COG0662	Cupin 2, conserved barrel domain protein
SHJG_RS18665	COG0174	glutamine synthetase
SHJG_RS18670	COG1335	isochorismatase
SHJG_RS18690	COG0501	Belongs to the peptidase M48B family
SHJG_RS18730	COG2267	carboxylic ester hydrolase activity
SHJG_RS18745	COG0745	RESPONSE REGULATOR receiver
SHJG_RS18815	COG0366	Alpha amylase catalytic
SHJG_RS18820	COG3833	ABC-type maltose transport systems, permease component
SHJG_RS18825	COG1175	transmembrane transport
SHJG_RS18835	COG1609	Transcriptional regulator
SHJG_RS18845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SHJG_RS18855	COG3511	phospholipase C
SHJG_RS18875	COG0174	glutamine synthetase
SHJG_RS18885	COG1959	2 iron, 2 sulfur cluster binding
SHJG_RS18930	COG2814	Major facilitator Superfamily
SHJG_RS18945	COG0477	Major facilitator Superfamily
SHJG_RS18950	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SHJG_RS18975	COG1994	Peptidase M50
SHJG_RS19035	COG2837	iron assimilation
SHJG_RS19040	COG0672	)-iron permease
SHJG_RS19065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJG_RS19070	COG2814	Major facilitator Superfamily
SHJG_RS19085	COG1686	Belongs to the peptidase S11 family
SHJG_RS19100	COG2259	Doxx family
SHJG_RS19110	COG2801	Transposase and inactivated derivatives
SHJG_RS19110	COG3415	Transposase
SHJG_RS19120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SHJG_RS19145	COG0557	exoribonuclease II activity
SHJG_RS19150	COG3022	response to hydroperoxide
SHJG_RS19155	COG0800	Aldolase
SHJG_RS19170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SHJG_RS19180	COG2030	dehydratase
SHJG_RS19185	COG4585	Histidine kinase
SHJG_RS19200	COG2197	response regulator
SHJG_RS19215	COG0477	Major facilitator Superfamily
SHJG_RS19225	COG0860	N-Acetylmuramoyl-L-alanine amidase
SHJG_RS19225	COG2247	cell wall binding repeat
SHJG_RS19260	COG0438	transferase activity, transferring glycosyl groups
SHJG_RS19265	COG1309	transcriptional regulator
SHJG_RS19295	COG1657	PFAM Prenyltransferase squalene oxidase
SHJG_RS19310	COG3845	ABC transporter
SHJG_RS19330	COG3619	membrane
SHJG_RS19335	COG2124	cytochrome p450
SHJG_RS19340	COG0183	Belongs to the thiolase family
SHJG_RS19355	COG4122	O-methyltransferase activity
SHJG_RS19395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SHJG_RS19465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJG_RS19475	COG1358	cellular component organization or biogenesis
SHJG_RS19520	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SHJG_RS19525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SHJG_RS19535	COG0477	Major facilitator Superfamily
SHJG_RS19540	COG1309	transcriptional regulator
SHJG_RS19555	COG0789	Transcriptional regulator
SHJG_RS19570	COG1741	Belongs to the pirin family
SHJG_RS19585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJG_RS19590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJG_RS19595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJG_RS19630	COG2130	NADP-dependent
SHJG_RS19635	COG1764	response to oxidative stress
SHJG_RS19675	COG4214	carbohydrate transport
SHJG_RS19685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJG_RS19725	COG3386	PFAM SMP-30 Gluconolaconase
SHJG_RS19730	COG1414	Transcriptional regulator
SHJG_RS19755	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS19760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SHJG_RS19760	COG0825	malonyl-CoA metabolic process
SHJG_RS19765	COG1404	Belongs to the peptidase S8 family
SHJG_RS19790	COG1077	Cell shape determining protein MreB Mrl
SHJG_RS19810	COG0515	serine threonine protein kinase
SHJG_RS19810	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJG_RS19815	COG0367	asparagine synthase
SHJG_RS19865	COG1487	ribonuclease activity
SHJG_RS19890	COG1070	Carbohydrate kinase
SHJG_RS19905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SHJG_RS19915	COG0358	DNA primase activity
SHJG_RS19925	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SHJG_RS19935	COG2949	membrane
SHJG_RS19940	COG0243	molybdopterin cofactor binding
SHJG_RS19980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJG_RS19985	COG2146	nitrite reductase [NAD(P)H] activity
SHJG_RS19985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJG_RS19995	COG2130	NADP-dependent
SHJG_RS20000	COG1309	transcriptional regulator
SHJG_RS20005	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS20010	COG0395	ABC-type sugar transport system, permease component
SHJG_RS20015	COG1175	transmembrane transport
SHJG_RS20035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJG_RS20035	COG0574	Belongs to the PEP-utilizing enzyme family
SHJG_RS20040	COG1846	Transcriptional regulator
SHJG_RS20040	COG1940	carbohydrate kinase activity
SHJG_RS20045	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SHJG_RS20075	COG0477	Major facilitator Superfamily
SHJG_RS20085	COG0423	glycine-tRNA ligase activity
SHJG_RS20100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SHJG_RS20110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SHJG_RS20115	COG1381	Involved in DNA repair and RecF pathway recombination
SHJG_RS20160	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS20190	COG1309	transcriptional regulator
SHJG_RS20200	COG0702	epimerase
SHJG_RS20230	COG0747	negative chemotaxis
SHJG_RS20240	COG0444	Belongs to the ABC transporter superfamily
SHJG_RS20245	COG4608	Belongs to the ABC transporter superfamily
SHJG_RS20250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJG_RS20265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SHJG_RS20295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SHJG_RS20315	COG2315	Protein conserved in bacteria
SHJG_RS20325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SHJG_RS20335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJG_RS20340	COG4948	Mandelate Racemase Muconate Lactonizing
SHJG_RS20350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJG_RS20355	COG1234	tRNA 3'-trailer cleavage
SHJG_RS20360	COG0537	adenosine 5'-monophosphoramidase activity
SHJG_RS20365	COG4946	Tricorn protease homolog
SHJG_RS20365	COG0793	Belongs to the peptidase S41A family
SHJG_RS20385	COG2070	2-Nitropropane dioxygenase
SHJG_RS20390	COG0484	heat shock protein binding
SHJG_RS20395	COG1420	regulation of RNA biosynthetic process
SHJG_RS20430	COG0481	GTPase activity
SHJG_RS20435	COG0268	Binds directly to 16S ribosomal RNA
SHJG_RS20450	COG2353	YceI-like domain
SHJG_RS20465	COG1555	photosystem II stabilization
SHJG_RS20465	COG1596	polysaccharide export
SHJG_RS20475	COG1307	EDD domain protein, DegV family
SHJG_RS20485	COG0495	leucyl-tRNA aminoacylation
SHJG_RS20495	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHJG_RS20520	COG0588	phosphoglycerate mutase activity
SHJG_RS20535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SHJG_RS20550	COG0501	Belongs to the peptidase M48B family
SHJG_RS20565	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SHJG_RS20575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SHJG_RS20590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJG_RS20595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJG_RS20605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SHJG_RS20610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SHJG_RS20615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SHJG_RS20620	COG0371	Dehydrogenase
SHJG_RS20630	COG1530	ribonuclease E activity
SHJG_RS20655	COG0772	Belongs to the SEDS family
SHJG_RS20660	COG0768	penicillin binding
SHJG_RS20675	COG1077	Cell shape determining protein MreB Mrl
SHJG_RS20680	COG0105	UTP biosynthetic process
SHJG_RS20690	COG0285	dihydrofolate synthase activity
SHJG_RS20695	COG0525	valine-tRNA ligase activity
SHJG_RS20705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SHJG_RS20710	COG0740	serine-type endopeptidase activity
SHJG_RS20715	COG0740	serine-type endopeptidase activity
SHJG_RS20720	COG0544	peptidyl-prolyl cis-trans isomerase activity
SHJG_RS20740	COG3594	Acyltransferase
SHJG_RS20755	COG4552	Acetyltransferase involved in intracellular survival and related
SHJG_RS20770	COG1113	amino acid transport
SHJG_RS20785	COG1113	amino acid transport
SHJG_RS20790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SHJG_RS20795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SHJG_RS20810	COG2755	lipolytic protein G-D-S-L family
SHJG_RS20840	COG0346	lactoylglutathione lyase activity
SHJG_RS20895	COG0697	spore germination
SHJG_RS20900	COG1846	Transcriptional regulator
SHJG_RS20920	COG1595	DNA-templated transcription, initiation
SHJG_RS20930	COG1131	(ABC) transporter
SHJG_RS20950	COG0668	transmembrane transport
SHJG_RS20970	COG1653	transport
SHJG_RS20975	COG1175	transmembrane transport
SHJG_RS20980	COG0395	ABC-type sugar transport system, permease component
SHJG_RS20985	COG1486	melibiose metabolic process
SHJG_RS20995	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SHJG_RS21005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJG_RS21040	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SHJG_RS21060	COG1136	(ABC) transporter
SHJG_RS21105	COG0629	single-stranded DNA binding
SHJG_RS21110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SHJG_RS21130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SHJG_RS21190	COG0297	glycogen (starch) synthase activity
SHJG_RS21195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SHJG_RS21215	COG0438	transferase activity, transferring glycosyl groups
SHJG_RS21255	COG1022	Amp-dependent synthetase and ligase
SHJG_RS21270	COG1131	(ABC) transporter
SHJG_RS21290	COG3962	Belongs to the TPP enzyme family
SHJG_RS21295	COG3718	enzyme involved in inositol metabolism
SHJG_RS21305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJG_RS21320	COG2409	Drug exporters of the RND superfamily
SHJG_RS21360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SHJG_RS21390	COG1129	ABC transporter
SHJG_RS21400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJG_RS21405	COG1869	D-ribose catabolic process
SHJG_RS21420	COG0673	inositol 2-dehydrogenase activity
SHJG_RS21425	COG1609	Transcriptional regulator
SHJG_RS21435	COG0456	acetyltransferase
SHJG_RS21435	COG1846	Transcriptional regulator
SHJG_RS21455	COG1472	Belongs to the glycosyl hydrolase 3 family
SHJG_RS21490	COG0028	Belongs to the TPP enzyme family
SHJG_RS21500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJG_RS21520	COG1946	Acyl-CoA thioesterase
SHJG_RS21530	COG1309	transcriptional regulator
SHJG_RS21535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SHJG_RS21550	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS21570	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SHJG_RS21605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SHJG_RS21610	COG0589	response to stress
SHJG_RS21620	COG4977	sequence-specific DNA binding
SHJG_RS21625	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SHJG_RS21645	COG0395	ABC-type sugar transport system, permease component
SHJG_RS21670	COG3979	chitinase
SHJG_RS21680	COG0745	RESPONSE REGULATOR receiver
SHJG_RS21705	COG0406	alpha-ribazole phosphatase activity
SHJG_RS21730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS21760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SHJG_RS21765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJG_RS21770	COG0765	amino acid transport
SHJG_RS21775	COG0765	amino acid transport
SHJG_RS21780	COG1126	abc transporter atp-binding protein
SHJG_RS21800	COG3397	chitin binding
SHJG_RS21820	COG2186	Transcriptional regulator
SHJG_RS21845	COG1940	carbohydrate kinase activity
SHJG_RS21850	COG0673	inositol 2-dehydrogenase activity
SHJG_RS21855	COG4702	Belongs to the UPF0303 family
SHJG_RS21870	COG0706	membrane insertase activity
SHJG_RS21890	COG3764	Sortase (surface protein transpeptidase)
SHJG_RS21960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJG_RS21990	COG2271	Major facilitator Superfamily
SHJG_RS21995	COG2733	membrane
SHJG_RS22005	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SHJG_RS22045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJG_RS22060	COG4555	ABC transporter
SHJG_RS22075	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SHJG_RS22080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SHJG_RS22085	COG1263	PTS System
SHJG_RS22090	COG1263	PTS System
SHJG_RS22125	COG1113	amino acid transport
SHJG_RS22135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SHJG_RS22145	COG1335	isochorismatase
SHJG_RS22150	COG2801	Transposase and inactivated derivatives
SHJG_RS22150	COG3415	Transposase
SHJG_RS22185	COG0277	FAD linked oxidase domain protein
SHJG_RS22195	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SHJG_RS22250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SHJG_RS22265	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SHJG_RS22275	COG1678	Uncharacterized ACR, COG1678
SHJG_RS22280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SHJG_RS22285	COG0776	regulation of translation
SHJG_RS22295	COG3973	AAA domain
SHJG_RS22315	COG2223	nitrite transmembrane transporter activity
SHJG_RS22340	COG0583	DNA-binding transcription factor activity
SHJG_RS22350	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SHJG_RS22355	COG0793	Belongs to the peptidase S41A family
SHJG_RS22360	COG2177	Part of the ABC transporter FtsEX involved in
SHJG_RS22365	COG2884	Cell division ATP-binding protein ftsE
SHJG_RS22380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SHJG_RS22385	COG0515	serine threonine protein kinase
SHJG_RS22390	COG0515	serine threonine protein kinase
SHJG_RS22395	COG1674	ftsk spoiiie
SHJG_RS22405	COG1175	transmembrane transport
SHJG_RS22410	COG0395	ABC-type sugar transport system, permease component
SHJG_RS22415	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJG_RS22420	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJG_RS22425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJG_RS22425	COG0463	Glycosyl transferase, family 2
SHJG_RS22430	COG1764	response to oxidative stress
SHJG_RS22435	COG1846	Transcriptional regulator
SHJG_RS22450	COG1215	transferase activity, transferring glycosyl groups
SHJG_RS22465	COG1134	teichoic acid transport
SHJG_RS22470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJG_RS22475	COG1215	transferase activity, transferring glycosyl groups
SHJG_RS22485	COG2902	Dehydrogenase
SHJG_RS22510	COG0653	protein targeting
SHJG_RS22520	COG3214	Protein conserved in bacteria
SHJG_RS22525	COG3415	Transposase
SHJG_RS22525	COG2801	Transposase and inactivated derivatives
SHJG_RS22530	COG2197	response regulator
SHJG_RS22535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SHJG_RS22545	COG0823	Involved in the tonB-independent uptake of proteins
SHJG_RS22550	COG5002	protein histidine kinase activity
SHJG_RS22550	COG5000	phosphorelay sensor kinase activity
SHJG_RS22555	COG0745	RESPONSE REGULATOR receiver
SHJG_RS22580	COG0714	Associated with various cellular activities
SHJG_RS22620	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SHJG_RS22625	COG0681	Belongs to the peptidase S26 family
SHJG_RS22635	COG1482	cell wall glycoprotein biosynthetic process
SHJG_RS22685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SHJG_RS22690	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SHJG_RS22690	COG0778	Nitroreductase
SHJG_RS22720	COG1316	TRANSCRIPTIONal
SHJG_RS22725	COG1316	TRANSCRIPTIONal
SHJG_RS22735	COG1316	TRANSCRIPTIONal
SHJG_RS22745	COG1316	TRANSCRIPTIONal
SHJG_RS22760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SHJG_RS22785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SHJG_RS22800	COG2205	protein histidine kinase activity
SHJG_RS22805	COG0745	RESPONSE REGULATOR receiver
SHJG_RS22810	COG3104	oligopeptide transport
SHJG_RS22825	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJG_RS22830	COG1191	sigma factor activity
SHJG_RS22840	COG1228	amidohydrolase
SHJG_RS22850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJG_RS22855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SHJG_RS22895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SHJG_RS22905	COG4221	oxidoreductase activity
SHJG_RS22920	COG2755	lipolytic protein G-D-S-L family
SHJG_RS22925	COG0183	Belongs to the thiolase family
SHJG_RS22960	COG1136	(ABC) transporter
SHJG_RS22960	COG0577	efflux transmembrane transporter activity
SHJG_RS22965	COG0577	efflux transmembrane transporter activity
SHJG_RS22970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SHJG_RS22975	COG1252	NADH dehydrogenase
SHJG_RS22995	COG0148	phosphopyruvate hydratase activity
SHJG_RS23015	COG2124	cytochrome p450
SHJG_RS23075	COG0789	Transcriptional regulator
SHJG_RS23085	COG0577	efflux transmembrane transporter activity
SHJG_RS23090	COG1136	(ABC) transporter
SHJG_RS23095	COG0477	Major facilitator Superfamily
SHJG_RS23125	COG4585	Histidine kinase
SHJG_RS23140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SHJG_RS23145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SHJG_RS23150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SHJG_RS23155	COG0193	aminoacyl-tRNA hydrolase activity
SHJG_RS23165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SHJG_RS23175	COG1309	transcriptional regulator
SHJG_RS23185	COG4106	trans-aconitate 2-methyltransferase activity
SHJG_RS23195	COG2197	response regulator
SHJG_RS23215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SHJG_RS23255	COG0488	(ABC) transporter
SHJG_RS23265	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SHJG_RS23270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SHJG_RS23275	COG3583	domain protein
SHJG_RS23275	COG3584	3D domain protein
SHJG_RS23280	COG0084	hydrolase, TatD family'
SHJG_RS23320	COG0310	cobalt ion transport
SHJG_RS23330	COG1122	ATPase activity
SHJG_RS23350	COG0442	prolyl-tRNA aminoacylation
SHJG_RS23355	COG2409	Drug exporters of the RND superfamily
SHJG_RS23365	COG4946	Tricorn protease homolog
SHJG_RS23365	COG0793	Belongs to the peptidase S41A family
SHJG_RS23375	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS23380	COG2267	carboxylic ester hydrolase activity
SHJG_RS23385	COG2072	flavoprotein involved in K transport
SHJG_RS23415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SHJG_RS23420	COG0315	cyclic pyranopterin monophosphate synthase activity
SHJG_RS23420	COG0521	Mo-molybdopterin cofactor biosynthetic process
SHJG_RS23425	COG0315	cyclic pyranopterin monophosphate synthase activity
SHJG_RS23435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SHJG_RS23440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SHJG_RS23455	COG3263	regulation of cellular component size
SHJG_RS23470	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SHJG_RS23490	COG3191	aminopeptidase activity
SHJG_RS23495	COG1376	ErfK ybiS ycfS ynhG family protein
SHJG_RS23510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SHJG_RS23510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SHJG_RS23510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SHJG_RS23515	COG1105	Belongs to the carbohydrate kinase PfkB family
SHJG_RS23520	COG1349	DNA-binding transcription factor activity
SHJG_RS23525	COG0477	Major facilitator Superfamily
SHJG_RS23545	COG1247	-acetyltransferase
SHJG_RS23550	COG3384	dioxygenase
SHJG_RS23555	COG1846	Transcriptional regulator
SHJG_RS23560	COG3415	Transposase
SHJG_RS23560	COG2801	Transposase and inactivated derivatives
SHJG_RS23580	COG1414	Transcriptional regulator
SHJG_RS23600	COG0582	viral genome integration into host DNA
SHJG_RS23620	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS23665	COG0277	FAD linked oxidase domain protein
SHJG_RS23680	COG0386	Belongs to the glutathione peroxidase family
SHJG_RS23700	COG1686	Belongs to the peptidase S11 family
SHJG_RS23740	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SHJG_RS23760	COG3903	Transcriptional regulator
SHJG_RS23760	COG3629	intracellular signal transduction
SHJG_RS23810	COG0515	serine threonine protein kinase
SHJG_RS23810	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJG_RS23825	COG1522	sequence-specific DNA binding
SHJG_RS23830	COG1280	lysine exporter protein (LysE YggA)
SHJG_RS23840	COG0259	pyridoxamine-phosphate oxidase activity
SHJG_RS23850	COG2072	flavoprotein involved in K transport
SHJG_RS23885	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJG_RS23930	COG0596	Alpha beta hydrolase
SHJG_RS23930	COG2945	thiolester hydrolase activity
SHJG_RS23940	COG4821	SIS domain
SHJG_RS23955	COG0259	pyridoxamine-phosphate oxidase activity
SHJG_RS23970	COG1309	transcriptional regulator
SHJG_RS23980	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS23990	COG4770	biotin carboxylase activity
SHJG_RS23995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SHJG_RS24010	COG0281	malic enzyme
SHJG_RS24015	COG5006	permease, DMT superfamily
SHJG_RS24020	COG1132	(ABC) transporter
SHJG_RS24035	COG0247	lactate metabolic process
SHJG_RS24035	COG0277	FAD linked oxidase domain protein
SHJG_RS24040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SHJG_RS24055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJG_RS24060	COG0667	Aldo Keto reductase
SHJG_RS24090	COG2252	PERMEase
SHJG_RS24100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SHJG_RS24130	COG2326	polyphosphate kinase activity
SHJG_RS24155	COG2814	Major facilitator Superfamily
SHJG_RS24165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SHJG_RS24170	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SHJG_RS24175	COG1278	Cold shock
SHJG_RS24205	COG1061	Type III restriction enzyme res subunit
SHJG_RS24210	COG1231	oxidoreductase activity
SHJG_RS24230	COG3973	AAA domain
SHJG_RS24250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SHJG_RS24265	COG1737	Transcriptional regulator
SHJG_RS24270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SHJG_RS24285	COG0459	protein refolding
SHJG_RS24290	COG1278	Cold shock
SHJG_RS24305	COG0463	Glycosyl transferase, family 2
SHJG_RS24355	COG3300	MHYT domain
SHJG_RS24355	COG5001	Diguanylate cyclase
SHJG_RS24375	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SHJG_RS24435	COG3842	ATPase activity
SHJG_RS24460	COG0215	cysteine-tRNA ligase activity
SHJG_RS24470	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SHJG_RS24475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SHJG_RS24480	COG1329	Transcriptional regulator
SHJG_RS24495	COG5002	protein histidine kinase activity
SHJG_RS24525	COG0588	phosphoglycerate mutase activity
SHJG_RS24615	COG0438	transferase activity, transferring glycosyl groups
SHJG_RS24650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SHJG_RS24665	COG1309	transcriptional regulator
SHJG_RS24680	COG2186	Transcriptional regulator
SHJG_RS24690	COG2188	Transcriptional regulator
SHJG_RS24700	COG1490	D-aminoacyl-tRNA deacylase activity
SHJG_RS24720	COG2897	thiosulfate sulfurtransferase activity
SHJG_RS24745	COG3485	protocatechuate 3,4-dioxygenase
SHJG_RS24755	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SHJG_RS24770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SHJG_RS24775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJG_RS24795	COG0745	RESPONSE REGULATOR receiver
SHJG_RS24800	COG1609	Transcriptional regulator
SHJG_RS24805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SHJG_RS24815	COG0745	RESPONSE REGULATOR receiver
SHJG_RS24825	COG1846	Transcriptional regulator
SHJG_RS24835	COG0737	Belongs to the 5'-nucleotidase family
SHJG_RS24840	COG0456	acetyltransferase
SHJG_RS24850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SHJG_RS24860	COG0494	nUDIX hydrolase
SHJG_RS24860	COG0406	alpha-ribazole phosphatase activity
SHJG_RS24875	COG1937	Protein conserved in bacteria
SHJG_RS24885	COG0306	phosphate transporter
SHJG_RS24890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SHJG_RS24905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SHJG_RS24910	COG0277	FAD linked oxidase domain protein
SHJG_RS24915	COG0671	phosphoesterase, PA-phosphatase related
SHJG_RS25010	COG1252	NADH dehydrogenase
SHJG_RS25040	COG0579	oxidoreductase
SHJG_RS25045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SHJG_RS25055	COG0667	Aldo Keto reductase
SHJG_RS25075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SHJG_RS25075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SHJG_RS25085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SHJG_RS25090	COG0477	Major facilitator Superfamily
SHJG_RS25120	COG0513	Belongs to the DEAD box helicase family
SHJG_RS25155	COG0582	viral genome integration into host DNA
SHJG_RS25220	COG0494	nUDIX hydrolase
SHJG_RS25235	COG2188	Transcriptional regulator
SHJG_RS25240	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SHJG_RS25255	COG1643	Atp-dependent helicase
SHJG_RS25290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SHJG_RS25320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SHJG_RS25325	COG0047	phosphoribosylformylglycinamidine synthase activity
SHJG_RS25330	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SHJG_RS25360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SHJG_RS25375	COG0151	Belongs to the GarS family
SHJG_RS25405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SHJG_RS25410	COG0798	PFAM Bile acid sodium symporter
SHJG_RS25415	COG0640	Transcriptional regulator
SHJG_RS25430	COG2372	response to copper ion
SHJG_RS25430	COG1276	copper resistance
SHJG_RS25445	COG2375	cellular response to nickel ion
SHJG_RS25445	COG1132	(ABC) transporter
SHJG_RS25465	COG0433	COG0433 Predicted ATPase
SHJG_RS25480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SHJG_RS25515	COG1191	sigma factor activity
SHJG_RS25520	COG1191	sigma factor activity
SHJG_RS25530	COG0477	Major facilitator Superfamily
SHJG_RS25535	COG2353	YceI-like domain
SHJG_RS25540	COG3467	pyridoxamine 5'-phosphate
SHJG_RS25550	COG0477	Major facilitator Superfamily
SHJG_RS25555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SHJG_RS25565	COG2205	protein histidine kinase activity
SHJG_RS25570	COG0745	RESPONSE REGULATOR receiver
SHJG_RS25590	COG1846	Transcriptional regulator
SHJG_RS25625	COG2801	Transposase and inactivated derivatives
SHJG_RS25655	COG2188	Transcriptional regulator
SHJG_RS25725	COG0784	Response regulator, receiver
SHJG_RS25730	COG1309	transcriptional regulator
SHJG_RS25735	COG2814	Major facilitator Superfamily
SHJG_RS25740	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS25745	COG1595	DNA-templated transcription, initiation
SHJG_RS25755	COG3415	Transposase
SHJG_RS25755	COG2801	Transposase and inactivated derivatives
SHJG_RS25765	COG0251	oxidation-reduction process
SHJG_RS25775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SHJG_RS25790	COG0653	protein targeting
SHJG_RS25810	COG0006	proline dipeptidase activity
SHJG_RS25815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SHJG_RS25850	COG2837	iron assimilation
SHJG_RS25860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SHJG_RS25865	COG0561	phosphatase activity
SHJG_RS25905	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SHJG_RS25915	COG0561	phosphatase activity
SHJG_RS25920	COG4988	ABC transporter
SHJG_RS25925	COG1294	oxidase, subunit
SHJG_RS25930	COG1271	oxidase subunit
SHJG_RS25935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJG_RS25940	COG1609	Transcriptional regulator
SHJG_RS25960	COG2801	Transposase and inactivated derivatives
SHJG_RS25965	COG2963	transposase activity
SHJG_RS25975	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SHJG_RS26000	COG0662	Cupin 2, conserved barrel domain protein
SHJG_RS26005	COG1950	PFAM Membrane protein of
SHJG_RS26010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SHJG_RS26015	COG0626	cystathionine gamma-synthase activity
SHJG_RS26050	COG2814	Major facilitator Superfamily
SHJG_RS26070	COG0305	Participates in initiation and elongation during chromosome replication
SHJG_RS26080	COG0359	binds to the 23S rRNA
SHJG_RS26085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SHJG_RS26090	COG0629	single-stranded DNA binding
SHJG_RS26095	COG0360	Binds together with S18 to 16S ribosomal RNA
SHJG_RS26120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJG_RS26140	COG0617	tRNA 3'-terminal CCA addition
SHJG_RS26155	COG0515	serine threonine protein kinase
SHJG_RS26155	COG2815	serine threonine protein kinase
SHJG_RS26160	COG1595	DNA-templated transcription, initiation
SHJG_RS26170	COG0492	ferredoxin-NADP+ reductase activity
SHJG_RS26175	COG3118	belongs to the thioredoxin family
SHJG_RS26190	COG1192	Involved in chromosome partitioning
SHJG_RS26195	COG0357	Ribosomal RNA small subunit methyltransferase G
SHJG_RS26205	COG0706	membrane insertase activity
SHJG_RS26210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SHJG_RS26225	COG0592	DNA-directed DNA polymerase activity
SHJG_RS26230	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SHJG_RS26235	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SHJG_RS26240	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SHJG_RS26245	COG0187	DNA topoisomerase II activity
SHJG_RS26250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SHJG_RS26265	COG4249	Peptidase C14 caspase catalytic subunit p20
SHJG_RS26265	COG2319	Wd-40 repeat
SHJG_RS26265	COG4249	Peptidase C14 caspase catalytic subunit p20
SHJG_RS26265	COG2319	Wd-40 repeat
SHJG_RS26295	COG0515	serine threonine protein kinase
SHJG_RS26320	COG0705	Rhomboid family
SHJG_RS26345	COG3764	Sortase (surface protein transpeptidase)
SHJG_RS26350	COG3764	Sortase (surface protein transpeptidase)
SHJG_RS26355	COG0515	serine threonine protein kinase
SHJG_RS26360	COG0768	penicillin binding
SHJG_RS26375	COG1716	ATPase activity
SHJG_RS26380	COG1716	ATPase activity
SHJG_RS26420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SHJG_RS26425	COG2151	metal-sulfur cluster biosynthetic enzyme
SHJG_RS26430	COG3396	Phenylacetate-CoA oxygenase
SHJG_RS26435	COG3460	Phenylacetate-CoA oxygenase
SHJG_RS26440	COG3396	Phenylacetate-CoA oxygenase
SHJG_RS26465	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJG_RS26470	COG1309	transcriptional regulator
SHJG_RS26475	COG1522	sequence-specific DNA binding
SHJG_RS26505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SHJG_RS26510	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS26510	COG0604	alcohol dehydrogenase
SHJG_RS26510	COG3321	synthase
SHJG_RS26525	COG0515	serine threonine protein kinase
SHJG_RS26530	COG0515	serine threonine protein kinase
SHJG_RS26545	COG0022	dehydrogenase e1 component
SHJG_RS26550	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJG_RS26615	COG1362	aminopeptidase activity
SHJG_RS26620	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS26635	COG1741	Belongs to the pirin family
SHJG_RS26650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SHJG_RS26660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SHJG_RS26670	COG1289	transmembrane transporter activity
SHJG_RS26730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SHJG_RS26735	COG1957	nucleoside hydrolase
SHJG_RS26740	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SHJG_RS26745	COG0640	Transcriptional regulator
SHJG_RS26750	COG0366	Alpha amylase catalytic
SHJG_RS26800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJG_RS26805	COG1595	DNA-templated transcription, initiation
SHJG_RS26820	COG0513	Belongs to the DEAD box helicase family
SHJG_RS26825	COG1278	Cold shock
SHJG_RS26835	COG2197	response regulator
SHJG_RS26840	COG4585	Histidine kinase
SHJG_RS26855	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS26870	COG0477	Major facilitator Superfamily
SHJG_RS26880	COG1959	2 iron, 2 sulfur cluster binding
SHJG_RS26885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SHJG_RS26890	COG0531	amino acid
SHJG_RS26895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SHJG_RS26900	COG1191	sigma factor activity
SHJG_RS26970	COG0515	serine threonine protein kinase
SHJG_RS26970	COG2815	serine threonine protein kinase
SHJG_RS27000	COG0142	geranyltranstransferase activity
SHJG_RS27025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJG_RS27040	COG0717	Belongs to the dCTP deaminase family
SHJG_RS27045	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SHJG_RS27075	COG0247	lactate metabolic process
SHJG_RS27075	COG2181	nitrate reductase activity
SHJG_RS27080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SHJG_RS27085	COG0443	Heat shock 70 kDa protein
SHJG_RS27090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHJG_RS27095	COG0484	heat shock protein binding
SHJG_RS27100	COG0789	Transcriptional regulator
SHJG_RS27105	COG4213	ABC transporter substrate-binding protein
SHJG_RS27135	COG0542	response to heat
SHJG_RS27160	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SHJG_RS27175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SHJG_RS27185	COG0477	Major facilitator Superfamily
SHJG_RS27200	COG3483	tryptophan 2,3-dioxygenase activity
SHJG_RS27205	COG3844	kynureninase activity
SHJG_RS27215	COG4585	Histidine kinase
SHJG_RS27220	COG2197	response regulator
SHJG_RS27240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SHJG_RS27250	COG1802	Transcriptional regulator
SHJG_RS27255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SHJG_RS27275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SHJG_RS27280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SHJG_RS27310	COG1595	DNA-templated transcription, initiation
SHJG_RS27340	COG0701	Predicted permease
SHJG_RS27400	COG1408	metallophosphoesterase
SHJG_RS27410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJG_RS27420	COG0003	Pfam Anion-transporting ATPase
SHJG_RS27440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJG_RS27470	COG2267	carboxylic ester hydrolase activity
SHJG_RS27485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJG_RS27490	COG0659	secondary active sulfate transmembrane transporter activity
SHJG_RS27550	COG1205	dead DEAH box helicase
SHJG_RS27550	COG1111	helicase
SHJG_RS27555	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJG_RS27565	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SHJG_RS27585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SHJG_RS27585	COG1754	DNA topoisomerase type I activity
SHJG_RS27590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SHJG_RS27795	COG3629	intracellular signal transduction
SHJG_RS27795	COG3903	Transcriptional regulator
SHJG_RS27800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SHJG_RS27800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SHJG_RS27830	COG0640	Transcriptional regulator
SHJG_RS27855	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS27860	COG2318	DinB family
SHJG_RS27870	COG0076	glutamate decarboxylase activity
SHJG_RS27880	COG0789	Transcriptional regulator
SHJG_RS27895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SHJG_RS27900	COG2027	D-alanyl-D-alanine carboxypeptidase
SHJG_RS27910	COG0037	tRNA processing
SHJG_RS27925	COG0302	gtp cyclohydrolase
SHJG_RS27940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SHJG_RS27955	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SHJG_RS27955	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SHJG_RS27980	COG0649	NAD binding
SHJG_RS27995	COG2197	response regulator
SHJG_RS28020	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SHJG_RS28025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SHJG_RS28035	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SHJG_RS28055	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SHJG_RS28080	COG0739	heme binding
SHJG_RS28100	COG2205	protein histidine kinase activity
SHJG_RS28105	COG0745	RESPONSE REGULATOR receiver
SHJG_RS28115	COG1595	DNA-templated transcription, initiation
SHJG_RS28130	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SHJG_RS28155	COG0248	Ppx GppA phosphatase
SHJG_RS28160	COG1082	Xylose isomerase domain protein TIM barrel
SHJG_RS28165	COG1309	transcriptional regulator
SHJG_RS28170	COG0129	dihydroxy-acid dehydratase activity
SHJG_RS28175	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJG_RS28175	COG0515	serine threonine protein kinase
SHJG_RS28180	COG4991	sh3 domain protein
SHJG_RS28195	COG1129	ABC transporter
SHJG_RS28195	COG0842	Transport permease protein
SHJG_RS28205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SHJG_RS28210	COG0180	Tryptophanyl-tRNA synthetase
SHJG_RS28230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SHJG_RS28240	COG2223	nitrite transmembrane transporter activity
SHJG_RS28245	COG0123	including yeast histone deacetylase and acetoin utilization protein
SHJG_RS28290	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SHJG_RS28295	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SHJG_RS28300	COG0181	hydroxymethylbilane synthase activity
SHJG_RS28305	COG1648	precorrin-2 dehydrogenase activity
SHJG_RS28305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SHJG_RS28310	COG0113	porphobilinogen synthase activity
SHJG_RS28350	COG3629	intracellular signal transduction
SHJG_RS28350	COG3903	Transcriptional regulator
SHJG_RS28355	COG0018	arginyl-trna synthetase
SHJG_RS28360	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SHJG_RS28380	COG1690	Belongs to the RtcB family
SHJG_RS28400	COG0702	epimerase
SHJG_RS28415	COG1742	UPF0060 membrane protein
SHJG_RS28420	COG1733	regulation of RNA biosynthetic process
SHJG_RS28430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS28435	COG0431	NADPH-dependent FMN reductase
SHJG_RS28445	COG2205	protein histidine kinase activity
SHJG_RS28455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SHJG_RS28455	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SHJG_RS28465	COG2362	D-Aminopeptidase
SHJG_RS28495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SHJG_RS28525	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SHJG_RS28555	COG2226	methyltransferase
SHJG_RS28570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SHJG_RS28575	COG0406	alpha-ribazole phosphatase activity
SHJG_RS28590	COG0785	Cytochrome C biogenesis protein
SHJG_RS28595	COG1333	cytochrome c biogenesis protein
SHJG_RS28600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SHJG_RS28620	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SHJG_RS28625	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SHJG_RS28630	COG0163	prenyltransferase activity
SHJG_RS28640	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SHJG_RS28645	COG1573	uracil-dna glycosylase
SHJG_RS28660	COG1309	transcriptional regulator
SHJG_RS28675	COG0583	DNA-binding transcription factor activity
SHJG_RS28695	COG2226	methyltransferase
SHJG_RS28700	COG0515	serine threonine protein kinase
SHJG_RS28700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJG_RS28720	COG1278	Cold shock
SHJG_RS28725	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SHJG_RS28735	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SHJG_RS28745	COG3979	chitinase
SHJG_RS28765	COG2226	methyltransferase
SHJG_RS28785	COG0242	peptide deformylase activity
SHJG_RS28800	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS28805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS28810	COG0649	NAD binding
SHJG_RS28820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHJG_RS28825	COG1034	ATP synthesis coupled electron transport
SHJG_RS28830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SHJG_RS28835	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS28840	COG0839	Belongs to the complex I subunit 6 family
SHJG_RS28845	COG0713	ATP synthesis coupled electron transport
SHJG_RS28850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SHJG_RS28860	COG1007	ATP synthesis coupled electron transport
SHJG_RS28865	COG0514	ATP-dependent DNA helicase (RecQ)
SHJG_RS28880	COG0561	phosphatase activity
SHJG_RS28885	COG5280	Phage tail tape measure protein TP901
SHJG_RS28885	COG3953	SLT domain
SHJG_RS28890	COG0142	geranyltranstransferase activity
SHJG_RS28900	COG1131	(ABC) transporter
SHJG_RS28910	COG3415	Transposase
SHJG_RS28910	COG2801	Transposase and inactivated derivatives
SHJG_RS28935	COG0702	epimerase
SHJG_RS28940	COG1733	regulation of RNA biosynthetic process
SHJG_RS28945	COG1013	pyruvate-flavodoxin oxidoreductase activity
SHJG_RS28950	COG0674	pyruvate-flavodoxin oxidoreductase activity
SHJG_RS28950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SHJG_RS28970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS28975	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS28980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS28985	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SHJG_RS28990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS28995	COG0839	Belongs to the complex I subunit 6 family
SHJG_RS29000	COG0713	ATP synthesis coupled electron transport
SHJG_RS29010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS29015	COG1007	ATP synthesis coupled electron transport
SHJG_RS29020	COG0501	Belongs to the peptidase M48B family
SHJG_RS29030	COG1672	PFAM Archaeal ATPase
SHJG_RS29030	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJG_RS29055	COG2261	transglycosylase associated protein
SHJG_RS29060	COG1666	GTP binding
SHJG_RS29085	COG0702	epimerase
SHJG_RS29105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SHJG_RS29110	COG2030	dehydratase
SHJG_RS29125	COG0477	Major facilitator Superfamily
SHJG_RS29135	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SHJG_RS29150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJG_RS29155	COG0436	Aminotransferase
SHJG_RS29170	COG0250	Participates in transcription elongation, termination and antitermination
SHJG_RS29180	COG0081	regulation of translation
SHJG_RS29200	COG0085	RNA polymerase activity
SHJG_RS29205	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SHJG_RS29240	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SHJG_RS29245	COG0049	tRNA binding
SHJG_RS29250	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SHJG_RS29270	COG0051	transcription antitermination factor activity, RNA binding
SHJG_RS29275	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SHJG_RS29280	COG0088	Forms part of the polypeptide exit tunnel
SHJG_RS29285	COG0089	rRNA binding
SHJG_RS29290	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SHJG_RS29295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SHJG_RS29300	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SHJG_RS29305	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SHJG_RS29310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SHJG_RS29315	COG0255	Belongs to the universal ribosomal protein uL29 family
SHJG_RS29320	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SHJG_RS29325	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SHJG_RS29330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SHJG_RS29335	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SHJG_RS29340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SHJG_RS29345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SHJG_RS29350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SHJG_RS29355	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SHJG_RS29360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SHJG_RS29365	COG1841	ribosomal large subunit assembly
SHJG_RS29370	COG0200	Binds to the 23S rRNA
SHJG_RS29380	COG0563	adenylate kinase activity
SHJG_RS29390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SHJG_RS29395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SHJG_RS29400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SHJG_RS29405	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SHJG_RS29410	COG0202	RNA polymerase activity
SHJG_RS29415	COG0203	ribosomal protein L17
SHJG_RS29420	COG0101	tRNA pseudouridine synthase activity
SHJG_RS29440	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SHJG_RS29455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SHJG_RS29460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SHJG_RS29465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SHJG_RS29475	COG1072	(Pantothenic acid kinase))
SHJG_RS29480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SHJG_RS29485	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS29490	COG0736	holo-[acyl-carrier-protein] synthase activity
SHJG_RS29500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SHJG_RS29510	COG0802	atpase or kinase
SHJG_RS29535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SHJG_RS29550	COG1609	Transcriptional regulator
SHJG_RS29565	COG4941	Belongs to the sigma-70 factor family
SHJG_RS29575	COG0726	polysaccharide deacetylase
SHJG_RS29580	COG0726	polysaccharide deacetylase
SHJG_RS29590	COG0459	protein refolding
SHJG_RS29600	COG4221	oxidoreductase activity
SHJG_RS29610	COG0583	DNA-binding transcription factor activity
SHJG_RS29625	COG1595	DNA-templated transcription, initiation
SHJG_RS29635	COG0516	GMP reductase activity
SHJG_RS29645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SHJG_RS29655	COG0515	serine threonine protein kinase
SHJG_RS29655	COG2815	serine threonine protein kinase
SHJG_RS29660	COG0515	serine threonine protein kinase
SHJG_RS29665	COG0515	serine threonine protein kinase
SHJG_RS29665	COG2815	serine threonine protein kinase
SHJG_RS29680	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS29695	COG0519	Catalyzes the synthesis of GMP from XMP
SHJG_RS29695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SHJG_RS29750	COG2197	response regulator
SHJG_RS29755	COG0791	NLP P60 protein
SHJG_RS29765	COG0791	NLP P60 protein
SHJG_RS29775	COG0739	heme binding
SHJG_RS29785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJG_RS29785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJG_RS29800	COG0714	Associated with various cellular activities
SHJG_RS29805	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SHJG_RS29815	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SHJG_RS29820	COG0045	succinate-CoA ligase (ADP-forming) activity
SHJG_RS29850	COG0138	bifunctional purine biosynthesis protein purh
SHJG_RS29855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJG_RS29870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJG_RS29895	COG2409	Drug exporters of the RND superfamily
SHJG_RS29905	COG3629	intracellular signal transduction
SHJG_RS29905	COG3903	Transcriptional regulator
SHJG_RS29910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS29915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJG_RS29925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS29950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJG_RS29995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SHJG_RS30005	COG4585	Histidine kinase
SHJG_RS30010	COG2197	response regulator
SHJG_RS30020	COG0039	L-malate dehydrogenase activity
SHJG_RS30035	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS30045	COG4175	Glycine betaine
SHJG_RS30045	COG0517	IMP dehydrogenase activity
SHJG_RS30050	COG4176	ABC-type proline glycine betaine transport system permease component
SHJG_RS30065	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJG_RS30070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SHJG_RS30085	COG0754	glutathionylspermidine amidase activity
SHJG_RS30100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SHJG_RS30105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SHJG_RS30110	COG0180	Tryptophanyl-tRNA synthetase
SHJG_RS30125	COG1295	ribonuclease BN
SHJG_RS30140	COG1408	metallophosphoesterase
SHJG_RS30155	COG1309	transcriptional regulator
SHJG_RS30170	COG1053	succinate dehydrogenase
SHJG_RS30180	COG2009	succinate dehydrogenase
SHJG_RS30190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SHJG_RS30220	COG1595	DNA-templated transcription, initiation
SHJG_RS30235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJG_RS30235	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJG_RS30255	COG1216	Glycosyl transferase, family 2
SHJG_RS30270	COG2089	acid synthase
SHJG_RS30290	COG1473	amidohydrolase
SHJG_RS30290	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SHJG_RS30295	COG1744	ABC transporter substrate-binding protein PnrA-like
SHJG_RS30300	COG3845	ABC transporter
SHJG_RS30305	COG4603	Belongs to the binding-protein-dependent transport system permease family
SHJG_RS30310	COG1079	Belongs to the binding-protein-dependent transport system permease family
SHJG_RS30335	COG2814	Major facilitator Superfamily
SHJG_RS30340	COG0583	DNA-binding transcription factor activity
SHJG_RS30350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJG_RS30375	COG2205	protein histidine kinase activity
SHJG_RS30380	COG0745	RESPONSE REGULATOR receiver
SHJG_RS30385	COG1595	DNA-templated transcription, initiation
SHJG_RS30400	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS30405	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS30425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SHJG_RS30450	COG4770	biotin carboxylase activity
SHJG_RS30460	COG0424	maF-like protein
SHJG_RS30470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SHJG_RS30480	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJG_RS30490	COG1024	Enoyl-CoA hydratase
SHJG_RS30500	COG2986	histidine ammonia-lyase
SHJG_RS30530	COG1136	(ABC) transporter
SHJG_RS30535	COG1404	Belongs to the peptidase S8 family
SHJG_RS30545	COG1064	alcohol dehydrogenase
SHJG_RS30555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SHJG_RS30565	COG0501	Belongs to the peptidase M48B family
SHJG_RS30585	COG1595	DNA-templated transcription, initiation
SHJG_RS30590	COG2255	four-way junction helicase activity
SHJG_RS30595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SHJG_RS30610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SHJG_RS30620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJG_RS30635	COG1331	Highly conserved protein containing a thioredoxin domain
SHJG_RS30645	COG1309	transcriptional regulator
SHJG_RS30655	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SHJG_RS30690	COG0436	Aminotransferase
SHJG_RS30710	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SHJG_RS30725	COG1414	Transcriptional regulator
SHJG_RS30735	COG2610	gluconate transmembrane transporter activity
SHJG_RS30760	COG3209	COG3209 Rhs family protein
SHJG_RS30790	COG2894	cell division
SHJG_RS30820	COG3920	Histidine kinase
SHJG_RS30825	COG2197	response regulator
SHJG_RS30865	COG2226	methyltransferase
SHJG_RS30870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SHJG_RS30875	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SHJG_RS30880	COG0741	lytic transglycosylase activity
SHJG_RS30890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJG_RS30895	COG0450	alkyl hydroperoxide reductase
SHJG_RS30910	COG1136	(ABC) transporter
SHJG_RS30930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJG_RS30945	COG0114	fumarate hydratase activity
SHJG_RS30950	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SHJG_RS30950	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SHJG_RS30975	COG0778	Nitroreductase
SHJG_RS30980	COG1722	exodeoxyribonuclease VII activity
SHJG_RS30985	COG1570	exodeoxyribonuclease VII activity
SHJG_RS30995	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SHJG_RS31010	COG0012	GTP binding
SHJG_RS31015	COG0582	viral genome integration into host DNA
SHJG_RS31020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SHJG_RS31030	COG1181	Belongs to the D-alanine--D-alanine ligase family
SHJG_RS31035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SHJG_RS31065	COG0778	Nitroreductase
SHJG_RS31065	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SHJG_RS31080	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SHJG_RS31085	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SHJG_RS31105	COG0592	DNA-directed DNA polymerase activity
SHJG_RS31115	COG1834	amidinotransferase
SHJG_RS31150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SHJG_RS31150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SHJG_RS31160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SHJG_RS31175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SHJG_RS31185	COG3629	intracellular signal transduction
SHJG_RS31185	COG3903	Transcriptional regulator
SHJG_RS31190	COG3629	intracellular signal transduction
SHJG_RS31190	COG3903	Transcriptional regulator
SHJG_RS31245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SHJG_RS31250	COG1053	succinate dehydrogenase
SHJG_RS31270	COG1217	gtp-binding protein TYPA
SHJG_RS31275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJG_RS31280	COG4166	transmembrane transport
SHJG_RS31285	COG0601	transmembrane transport
SHJG_RS31290	COG0444	Belongs to the ABC transporter superfamily
SHJG_RS31295	COG4608	Belongs to the ABC transporter superfamily
SHJG_RS31305	COG4608	Belongs to the ABC transporter superfamily
SHJG_RS31310	COG0444	Belongs to the ABC transporter superfamily
SHJG_RS31315	COG0601	transmembrane transport
SHJG_RS31320	COG4166	transmembrane transport
SHJG_RS31325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJG_RS31335	COG0601	transmembrane transport
SHJG_RS31340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJG_RS31350	COG4608	Belongs to the ABC transporter superfamily
SHJG_RS31365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJG_RS31380	COG1131	(ABC) transporter
SHJG_RS31390	COG4585	Histidine kinase
SHJG_RS31395	COG2197	response regulator
SHJG_RS31405	COG0456	acetyltransferase
SHJG_RS31405	COG1214	PFAM Peptidase M22, glycoprotease
SHJG_RS31430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJG_RS31435	COG1611	Belongs to the LOG family
SHJG_RS31440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SHJG_RS31450	COG0519	Catalyzes the synthesis of GMP from XMP
SHJG_RS31455	COG1024	Enoyl-CoA hydratase
SHJG_RS31465	COG1595	DNA-templated transcription, initiation
SHJG_RS31475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SHJG_RS31480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SHJG_RS31525	COG0598	Magnesium transport protein CorA
SHJG_RS31535	COG2814	Major facilitator Superfamily
SHJG_RS31550	COG2095	MarC family integral membrane protein
SHJG_RS31555	COG1432	Conserved Protein
SHJG_RS31610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJG_RS31680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJG_RS31685	COG2816	NAD+ diphosphatase activity
SHJG_RS31710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SHJG_RS31760	COG3480	Lon protease (S16) C-terminal proteolytic domain
SHJG_RS31770	COG1615	UPF0182 protein
SHJG_RS31795	COG0753	catalase activity
SHJG_RS31805	COG0483	inositol monophosphate 1-phosphatase activity
SHJG_RS31825	COG2076	Multidrug Resistance protein
SHJG_RS31835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SHJG_RS31845	COG2135	peptidase activity
SHJG_RS31855	COG1595	DNA-templated transcription, initiation
SHJG_RS31860	COG5662	AntiSigma factor
SHJG_RS31865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SHJG_RS31865	COG2199	diguanylate cyclase activity
SHJG_RS31880	COG0242	peptide deformylase activity
SHJG_RS31890	COG2124	cytochrome p450
SHJG_RS31910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SHJG_RS31940	COG2188	Transcriptional regulator
SHJG_RS31945	COG0363	glucosamine-6-phosphate deaminase activity
SHJG_RS31950	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS31970	COG1597	lipid kinase activity
SHJG_RS31985	COG2172	sigma factor antagonist activity
SHJG_RS32000	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SHJG_RS32010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SHJG_RS32015	COG0142	geranyltranstransferase activity
SHJG_RS32060	COG4106	trans-aconitate 2-methyltransferase activity
SHJG_RS32065	COG1126	abc transporter atp-binding protein
SHJG_RS32080	COG0281	malic enzyme
SHJG_RS32085	COG0604	alcohol dehydrogenase
SHJG_RS32125	COG2255	four-way junction helicase activity
SHJG_RS32150	COG0567	Dehydrogenase, E1 component
SHJG_RS32150	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJG_RS32155	COG2205	protein histidine kinase activity
SHJG_RS32160	COG0745	RESPONSE REGULATOR receiver
SHJG_RS32175	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SHJG_RS32255	COG0768	penicillin binding
SHJG_RS32260	COG0772	Belongs to the SEDS family
SHJG_RS32265	COG2205	protein histidine kinase activity
SHJG_RS32285	COG1793	dna ligase
SHJG_RS32285	COG3285	dna ligase
SHJG_RS32290	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SHJG_RS32365	COG2188	Transcriptional regulator
SHJG_RS32410	COG0018	arginyl-trna synthetase
SHJG_RS32415	COG0019	diaminopimelate decarboxylase activity
SHJG_RS32420	COG0460	homoserine dehydrogenase
SHJG_RS32425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SHJG_RS32430	COG0083	homoserine kinase activity
SHJG_RS32445	COG0254	rRNA binding
SHJG_RS32450	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SHJG_RS32455	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJG_RS32465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SHJG_RS32470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SHJG_RS32475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SHJG_RS32490	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SHJG_RS32495	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SHJG_RS32500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SHJG_RS32505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SHJG_RS32510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SHJG_RS32515	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SHJG_RS32520	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SHJG_RS32535	COG2197	response regulator
SHJG_RS32540	COG4585	Histidine kinase
SHJG_RS32550	COG2318	DinB family
SHJG_RS32560	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJG_RS32575	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SHJG_RS32635	COG0183	Belongs to the thiolase family
SHJG_RS32705	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJG_RS32705	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJG_RS32740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SHJG_RS32745	COG0280	phosphate acetyltransferase
SHJG_RS32745	COG0857	belongs to the CobB CobQ family
SHJG_RS32750	COG0205	6-phosphofructokinase activity
SHJG_RS32755	COG0395	ABC-type sugar transport system, permease component
SHJG_RS32760	COG1175	transmembrane transport
SHJG_RS32770	COG3903	Transcriptional regulator
SHJG_RS32770	COG3629	intracellular signal transduction
SHJG_RS32775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SHJG_RS32790	COG4565	transcriptional regulatory protein
SHJG_RS32795	COG3290	protein histidine kinase activity
SHJG_RS32800	COG1301	dicarboxylic acid transport
SHJG_RS32810	COG0477	Major facilitator Superfamily
SHJG_RS32830	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SHJG_RS32835	COG3281	Trehalose synthase
SHJG_RS32845	COG0366	Alpha amylase catalytic
SHJG_RS32850	COG0058	SHG alpha-glucan phosphorylase activity
SHJG_RS32855	COG3415	Transposase
SHJG_RS32855	COG2801	Transposase and inactivated derivatives
SHJG_RS32880	COG1132	(ABC) transporter
SHJG_RS32885	COG1132	(ABC) transporter
SHJG_RS32890	COG1132	(ABC) transporter
SHJG_RS32895	COG1132	(ABC) transporter
SHJG_RS32925	COG1376	ErfK ybiS ycfS ynhG family protein
SHJG_RS32930	COG1376	ErfK ybiS ycfS ynhG family protein
SHJG_RS32960	COG0789	Transcriptional regulator
SHJG_RS32970	COG1119	ATPase activity
SHJG_RS32975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SHJG_RS32995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SHJG_RS33020	COG1760	l-serine dehydratase
SHJG_RS33025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SHJG_RS33030	COG0509	glycine decarboxylation via glycine cleavage system
SHJG_RS33035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SHJG_RS33055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJG_RS33060	COG0747	negative chemotaxis
SHJG_RS33070	COG0444	Belongs to the ABC transporter superfamily
SHJG_RS33075	COG4608	Belongs to the ABC transporter superfamily
SHJG_RS33085	COG2860	membrane
SHJG_RS33105	COG2378	regulation of single-species biofilm formation
SHJG_RS33135	COG0482	sulfurtransferase activity
SHJG_RS33150	COG1611	Belongs to the LOG family
SHJG_RS33155	COG4221	oxidoreductase activity
SHJG_RS33165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SHJG_RS33190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SHJG_RS33195	COG0154	amidase activity
SHJG_RS33205	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SHJG_RS33215	COG2409	Drug exporters of the RND superfamily
SHJG_RS33220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SHJG_RS33235	COG2197	response regulator
SHJG_RS33245	COG2133	pyrroloquinoline quinone binding
SHJG_RS33250	COG0667	Aldo Keto reductase
SHJG_RS33260	COG5001	Diguanylate cyclase
SHJG_RS33270	COG0440	acetolactate synthase activity
SHJG_RS33275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SHJG_RS33280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SHJG_RS33285	COG0477	Major facilitator Superfamily
SHJG_RS33295	COG2508	Transcriptional regulator
SHJG_RS33300	COG0506	proline dehydrogenase activity
SHJG_RS33305	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS33315	COG2130	NADP-dependent
SHJG_RS33320	COG0583	DNA-binding transcription factor activity
SHJG_RS33330	COG0473	3-isopropylmalate dehydrogenase activity
SHJG_RS33335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SHJG_RS33340	COG0831	urea catabolic process
SHJG_RS33340	COG0832	Belongs to the urease beta subunit family
SHJG_RS33345	COG0804	urea catabolic process
SHJG_RS33350	COG2957	Belongs to the agmatine deiminase family
SHJG_RS33360	COG0477	Major facilitator Superfamily
SHJG_RS33365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SHJG_RS33415	COG2353	YceI-like domain
SHJG_RS33425	COG5492	domain, Protein
SHJG_RS33430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SHJG_RS33450	COG2018	Roadblock/LC7 domain
SHJG_RS33470	COG2018	Roadblock/LC7 domain
SHJG_RS33475	COG5002	protein histidine kinase activity
SHJG_RS33485	COG0179	Fumarylacetoacetate (FAA) hydrolase
SHJG_RS33490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SHJG_RS33540	COG1414	Transcriptional regulator
SHJG_RS33545	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SHJG_RS33550	COG0066	3-isopropylmalate dehydratase activity
SHJG_RS33560	COG0776	regulation of translation
SHJG_RS33570	COG1920	GTP binding
SHJG_RS33580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SHJG_RS33585	COG1181	Belongs to the D-alanine--D-alanine ligase family
SHJG_RS33605	COG0351	phosphomethylpyrimidine kinase
SHJG_RS33620	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SHJG_RS33625	COG1461	Dihydroxyacetone kinase
SHJG_RS33635	COG0326	Molecular chaperone. Has ATPase activity
SHJG_RS33645	COG0742	ribosomal rna small subunit methyltransferase
SHJG_RS33650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SHJG_RS33665	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SHJG_RS33670	COG0571	ribonuclease III activity
SHJG_RS33675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SHJG_RS33680	COG1733	regulation of RNA biosynthetic process
SHJG_RS33685	COG0655	NAD(P)H dehydrogenase (quinone) activity
SHJG_RS33695	COG1254	Belongs to the acylphosphatase family
SHJG_RS33705	COG1196	nuclear chromosome segregation
SHJG_RS33710	COG0477	Major facilitator Superfamily
SHJG_RS33750	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SHJG_RS33760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SHJG_RS33775	COG0228	four-way junction DNA binding
SHJG_RS33780	COG1837	Belongs to the UPF0109 family
SHJG_RS33785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SHJG_RS33790	COG0336	Belongs to the RNA methyltransferase TrmD family
SHJG_RS33795	COG0335	large ribosomal subunit rRNA binding
SHJG_RS33810	COG0681	Belongs to the peptidase S26 family
SHJG_RS33830	COG0792	nuclease activity
SHJG_RS33845	COG1191	sigma factor activity
SHJG_RS33860	COG0052	Belongs to the universal ribosomal protein uS2 family
SHJG_RS33865	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SHJG_RS33870	COG0528	UMP kinase activity
SHJG_RS33875	COG0233	cytoplasmic translational termination
SHJG_RS33880	COG0575	Belongs to the CDS family
SHJG_RS33885	COG2124	cytochrome p450
SHJG_RS33895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SHJG_RS33905	COG4208	sulfate ABC transporter
SHJG_RS33910	COG3842	ATPase activity
SHJG_RS33940	COG4181	ATPase activity
SHJG_RS33945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SHJG_RS33955	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS33965	COG2801	Transposase and inactivated derivatives
SHJG_RS33965	COG3415	Transposase
SHJG_RS33970	COG0395	ABC-type sugar transport system, permease component
SHJG_RS33975	COG1175	transmembrane transport
SHJG_RS33990	COG3876	Protein conserved in bacteria
SHJG_RS34000	COG1414	Transcriptional regulator
SHJG_RS34020	COG0584	glycerophosphoryl diester phosphodiesterase
SHJG_RS34025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJG_RS34050	COG3842	ATPase activity
SHJG_RS34055	COG1176	ABC-type spermidine putrescine transport system, permease component I
SHJG_RS34060	COG1177	transmembrane transport
SHJG_RS34065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJG_RS34100	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS34130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SHJG_RS34135	COG0750	zinc metalloprotease
SHJG_RS34140	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SHJG_RS34150	COG1247	-acetyltransferase
SHJG_RS34155	COG0442	prolyl-tRNA aminoacylation
SHJG_RS34175	COG0779	Required for maturation of 30S ribosomal subunits
SHJG_RS34185	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SHJG_RS34195	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SHJG_RS34200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SHJG_RS34215	COG0455	bacterial-type flagellum organization
SHJG_RS34230	COG3266	domain, Protein
SHJG_RS34235	COG1404	Belongs to the peptidase S8 family
SHJG_RS34270	COG1404	Belongs to the peptidase S8 family
SHJG_RS34290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJG_RS34290	COG0515	serine threonine protein kinase
SHJG_RS34295	COG0515	serine threonine protein kinase
SHJG_RS34295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJG_RS34300	COG1674	ftsk spoiiie
SHJG_RS34315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SHJG_RS34320	COG1185	polyribonucleotide nucleotidyltransferase activity
SHJG_RS34325	COG0612	Peptidase, M16
SHJG_RS34330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SHJG_RS34350	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SHJG_RS34355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJG_RS34360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SHJG_RS34390	COG2208	phosphoserine phosphatase activity
SHJG_RS34390	COG2770	Histidine kinase
SHJG_RS34395	COG2205	protein histidine kinase activity
SHJG_RS34395	COG0784	Response regulator, receiver
SHJG_RS34405	COG1674	ftsk spoiiie
SHJG_RS34415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SHJG_RS34425	COG1058	Belongs to the CinA family
SHJG_RS34425	COG1546	Belongs to the CinA family
SHJG_RS34430	COG1396	sequence-specific DNA binding
SHJG_RS34435	COG0783	Belongs to the Dps family
SHJG_RS34445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SHJG_RS34450	COG1201	RNA secondary structure unwinding
SHJG_RS34480	COG0628	permease
SHJG_RS34495	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SHJG_RS34525	COG0765	amino acid transport
SHJG_RS34530	COG0765	amino acid transport
SHJG_RS34535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJG_RS34540	COG1126	abc transporter atp-binding protein
SHJG_RS34545	COG0745	RESPONSE REGULATOR receiver
SHJG_RS34550	COG2205	protein histidine kinase activity
SHJG_RS34555	COG2358	TRAP transporter, solute receptor (TAXI family
SHJG_RS34590	COG0475	glutathione-regulated potassium exporter activity
SHJG_RS34595	COG3469	chitinase activity
SHJG_RS34615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SHJG_RS34635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SHJG_RS34645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SHJG_RS34650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SHJG_RS34660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SHJG_RS34690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SHJG_RS34695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SHJG_RS34700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SHJG_RS34735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SHJG_RS34775	COG2186	Transcriptional regulator
SHJG_RS34780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SHJG_RS34785	COG5640	endopeptidase activity
SHJG_RS34795	COG0187	DNA topoisomerase II activity
SHJG_RS34805	COG4585	Histidine kinase
SHJG_RS34810	COG2197	response regulator
SHJG_RS34820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJG_RS34835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SHJG_RS34850	COG4565	transcriptional regulatory protein
SHJG_RS34855	COG3290	protein histidine kinase activity
SHJG_RS34870	COG0372	Belongs to the citrate synthase family
SHJG_RS34875	COG0523	cobalamin synthesis protein
SHJG_RS34880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SHJG_RS34885	COG0612	Peptidase, M16
SHJG_RS34900	COG1802	Transcriptional regulator
SHJG_RS34905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SHJG_RS34930	COG1435	thymidine kinase activity
SHJG_RS34965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SHJG_RS34970	COG0483	inositol monophosphate 1-phosphatase activity
SHJG_RS34975	COG0745	RESPONSE REGULATOR receiver
SHJG_RS34980	COG2205	protein histidine kinase activity
SHJG_RS35005	COG0756	dUTP diphosphatase activity
SHJG_RS35015	COG1136	(ABC) transporter
SHJG_RS35045	COG0569	domain protein
SHJG_RS35050	COG0531	amino acid
SHJG_RS35055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SHJG_RS35100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SHJG_RS35115	COG1215	transferase activity, transferring glycosyl groups
SHJG_RS35125	COG4310	Domain of unknown function (DUF2172)
SHJG_RS35140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SHJG_RS35150	COG0438	transferase activity, transferring glycosyl groups
SHJG_RS35175	COG0367	asparagine synthase
SHJG_RS35195	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SHJG_RS35235	COG1799	cell septum assembly
SHJG_RS35240	COG0443	Heat shock 70 kDa protein
SHJG_RS35295	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJG_RS35300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SHJG_RS35340	COG2235	arginine
SHJG_RS35345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SHJG_RS35350	COG0531	amino acid
SHJG_RS35360	COG1024	Enoyl-CoA hydratase
SHJG_RS35395	COG2188	Transcriptional regulator
SHJG_RS35400	COG2182	Extracellular solute-binding protein
SHJG_RS35405	COG1175	transmembrane transport
SHJG_RS35410	COG0395	ABC-type sugar transport system, permease component
SHJG_RS35415	COG1472	Belongs to the glycosyl hydrolase 3 family
SHJG_RS35445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJG_RS35460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS35475	COG1595	DNA-templated transcription, initiation
SHJG_RS35485	COG1309	transcriptional regulator
SHJG_RS35490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SHJG_RS35495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SHJG_RS35500	COG3290	protein histidine kinase activity
SHJG_RS35505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHJG_RS35510	COG0443	Heat shock 70 kDa protein
SHJG_RS35515	COG0484	heat shock protein binding
SHJG_RS35525	COG3537	Alpha-1,2-mannosidase
SHJG_RS35535	COG1653	transport
SHJG_RS35540	COG1175	transmembrane transport
SHJG_RS35545	COG0395	ABC-type sugar transport system, permease component
SHJG_RS35550	COG1940	carbohydrate kinase activity
SHJG_RS35555	COG4213	ABC transporter substrate-binding protein
SHJG_RS35565	COG4214	carbohydrate transport
SHJG_RS35570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SHJG_RS35575	COG0531	amino acid
SHJG_RS35600	COG1024	Enoyl-CoA hydratase
SHJG_RS35600	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJG_RS35605	COG0183	Belongs to the thiolase family
SHJG_RS35610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SHJG_RS35625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SHJG_RS35640	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJG_RS35650	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SHJG_RS35655	COG3253	May function as heme-dependent peroxidase
SHJG_RS35675	COG3220	belongs to the UPF0276 family
SHJG_RS35690	COG4152	abc transporter atp-binding protein
SHJG_RS35710	COG0723	plastoquinol--plastocyanin reductase activity
SHJG_RS35710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJG_RS35715	COG2326	polyphosphate kinase activity
SHJG_RS35720	COG0330	HflC and HflK could
SHJG_RS35755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SHJG_RS35760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SHJG_RS35775	COG1174	glycine betaine transport
SHJG_RS35795	COG2018	Roadblock/LC7 domain
SHJG_RS35805	COG1732	Glycine betaine
SHJG_RS35810	COG2986	histidine ammonia-lyase
SHJG_RS35820	COG0640	Transcriptional regulator
SHJG_RS35920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SHJG_RS35925	COG0583	DNA-binding transcription factor activity
SHJG_RS35965	COG1175	transmembrane transport
SHJG_RS35990	COG2409	Drug exporters of the RND superfamily
SHJG_RS35995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SHJG_RS36000	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SHJG_RS36025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SHJG_RS36030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SHJG_RS36030	COG1116	anion transmembrane transporter activity
SHJG_RS36055	COG0529	Catalyzes the synthesis of activated sulfate
SHJG_RS36060	COG0175	sulfate reduction
SHJG_RS36075	COG0456	acetyltransferase
SHJG_RS36090	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS36120	COG3739	integral membrane protein
SHJG_RS36150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SHJG_RS36170	COG2040	homocysteine
SHJG_RS36175	COG3940	Belongs to the glycosyl hydrolase 43 family
SHJG_RS36240	COG1162	GTPase activity
SHJG_RS36250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SHJG_RS36270	COG0028	Belongs to the TPP enzyme family
SHJG_RS36290	COG1802	Transcriptional regulator
SHJG_RS36300	COG3835	regulator
SHJG_RS36315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SHJG_RS36320	COG2252	PERMEase
SHJG_RS36340	COG5634	Uncharacterized conserved protein (DUF2278)
SHJG_RS36355	COG0515	serine threonine protein kinase
SHJG_RS36370	COG1653	transport
SHJG_RS36390	COG2197	response regulator
SHJG_RS36395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJG_RS36400	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS36410	COG3960	tartronate-semialdehyde synthase activity
SHJG_RS36430	COG0753	catalase activity
SHJG_RS36435	COG2084	Dehydrogenase
SHJG_RS36440	COG3622	Belongs to the hyi family
SHJG_RS36460	COG2351	hydroxyisourate hydrolase activity
SHJG_RS36470	COG2233	PERMEase
SHJG_RS36480	COG2233	PERMEase
SHJG_RS36490	COG1733	regulation of RNA biosynthetic process
SHJG_RS36505	COG0406	alpha-ribazole phosphatase activity
SHJG_RS36520	COG0436	Aminotransferase
SHJG_RS36525	COG1733	regulation of RNA biosynthetic process
SHJG_RS36550	COG4264	IucA IucC family
SHJG_RS36565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SHJG_RS36585	COG1414	Transcriptional regulator
SHJG_RS36590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SHJG_RS36595	COG4266	Belongs to the allantoicase family
SHJG_RS36630	COG0673	inositol 2-dehydrogenase activity
SHJG_RS36635	COG2188	Transcriptional regulator
SHJG_RS36655	COG1940	carbohydrate kinase activity
SHJG_RS36665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SHJG_RS36745	COG1063	alcohol dehydrogenase
SHJG_RS36750	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SHJG_RS36755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SHJG_RS36760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SHJG_RS36770	COG0640	Transcriptional regulator
SHJG_RS36780	COG2814	Major facilitator Superfamily
SHJG_RS36790	COG0514	ATP-dependent DNA helicase (RecQ)
SHJG_RS36800	COG0604	alcohol dehydrogenase
SHJG_RS36845	COG3903	Transcriptional regulator
SHJG_RS36845	COG3629	intracellular signal transduction
SHJG_RS36880	COG1271	oxidase subunit
SHJG_RS36910	COG1024	Enoyl-CoA hydratase
SHJG_RS36920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SHJG_RS36925	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SHJG_RS36930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SHJG_RS36935	COG0254	rRNA binding
SHJG_RS36945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SHJG_RS36950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SHJG_RS36955	COG0456	acetyltransferase
SHJG_RS36980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SHJG_RS37000	COG0628	permease
SHJG_RS37005	COG1597	lipid kinase activity
SHJG_RS37015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJG_RS37035	COG0765	amino acid transport
SHJG_RS37050	COG0405	Gamma-glutamyltransferase
SHJG_RS37055	COG0542	response to heat
SHJG_RS37060	COG0024	Methionine aminopeptidase
SHJG_RS37080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SHJG_RS37095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SHJG_RS37100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS37105	COG1953	Uracil, thiamine, allantoin
SHJG_RS37130	COG0095	Lipoate-protein ligase
SHJG_RS37135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SHJG_RS37155	COG0483	inositol monophosphate 1-phosphatase activity
SHJG_RS37175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SHJG_RS37190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SHJG_RS37220	COG1929	Belongs to the glycerate kinase type-1 family
SHJG_RS37230	COG0688	phosphatidylethanolamine metabolic process
SHJG_RS37235	COG1960	acyl-CoA dehydrogenase activity
SHJG_RS37245	COG2301	Belongs to the HpcH HpaI aldolase family
SHJG_RS37250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJG_RS37250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJG_RS37265	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJG_RS37275	COG0456	acetyltransferase
SHJG_RS37305	COG2208	phosphoserine phosphatase activity
SHJG_RS37305	COG2172	sigma factor antagonist activity
SHJG_RS37305	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJG_RS37310	COG4106	trans-aconitate 2-methyltransferase activity
SHJG_RS37315	COG2362	D-Aminopeptidase
SHJG_RS37320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJG_RS37330	COG1619	proteins homologs of microcin C7 resistance protein MccF
SHJG_RS37350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS37365	COG3285	dna ligase
SHJG_RS37365	COG1793	dna ligase
SHJG_RS37435	COG0406	alpha-ribazole phosphatase activity
SHJG_RS37440	COG0488	(ABC) transporter
SHJG_RS37455	COG0693	protein deglycase activity
SHJG_RS37470	COG0028	Belongs to the TPP enzyme family
SHJG_RS37495	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SHJG_RS37530	COG2154	pterin-4-alpha-carbinolamine dehydratase
SHJG_RS37535	COG2226	methyltransferase
SHJG_RS37565	COG4733	cellulase activity
SHJG_RS37565	COG5297	Belongs to the glycosyl hydrolase family 6
SHJG_RS37575	COG5297	Belongs to the glycosyl hydrolase family 6
SHJG_RS37585	COG4106	trans-aconitate 2-methyltransferase activity
SHJG_RS37590	COG4221	oxidoreductase activity
SHJG_RS37605	COG0656	L-ascorbic acid biosynthetic process
SHJG_RS37610	COG1022	Amp-dependent synthetase and ligase
SHJG_RS37635	COG1846	Transcriptional regulator
SHJG_RS37640	COG1335	isochorismatase
SHJG_RS37645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SHJG_RS37655	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHJG_RS37660	COG3383	formate dehydrogenase (NAD+) activity
SHJG_RS37665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SHJG_RS37675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJG_RS37705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJG_RS37715	COG0045	succinate-CoA ligase (ADP-forming) activity
SHJG_RS37725	COG1012	belongs to the aldehyde dehydrogenase family
SHJG_RS37740	COG2182	Extracellular solute-binding protein
SHJG_RS37745	COG1175	transmembrane transport
SHJG_RS37750	COG0395	ABC-type sugar transport system, permease component
SHJG_RS37755	COG2723	6-phospho-beta-galactosidase activity
SHJG_RS37760	COG2273	Hydrolase Family 16
SHJG_RS37860	COG0297	glycogen (starch) synthase activity
SHJG_RS37880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SHJG_RS37905	COG0477	Major facilitator Superfamily
SHJG_RS37915	COG3467	pyridoxamine 5'-phosphate
SHJG_RS37920	COG2084	Dehydrogenase
SHJG_RS37930	COG0477	Major facilitator Superfamily
SHJG_RS37940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SHJG_RS37945	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SHJG_RS37945	COG1082	Xylose isomerase domain protein TIM barrel
SHJG_RS37955	COG0588	phosphoglycerate mutase activity
SHJG_RS37960	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SHJG_RS37965	COG0166	Belongs to the GPI family
SHJG_RS37980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SHJG_RS38005	COG1486	melibiose metabolic process
SHJG_RS38010	COG3469	chitinase activity
SHJG_RS38020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SHJG_RS38060	COG1175	transmembrane transport
SHJG_RS38065	COG0395	ABC-type sugar transport system, permease component
SHJG_RS38070	COG0366	Alpha amylase catalytic
SHJG_RS38080	COG3511	phospholipase C
SHJG_RS38110	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJG_RS38110	COG1672	PFAM Archaeal ATPase
SHJG_RS38120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJG_RS38130	COG3485	protocatechuate 3,4-dioxygenase
SHJG_RS38135	COG3485	protocatechuate 3,4-dioxygenase
SHJG_RS38155	COG1793	dna ligase
SHJG_RS38185	COG1834	amidinotransferase
SHJG_RS38190	COG0488	(ABC) transporter
SHJG_RS38215	COG1515	deoxyribonuclease V activity
SHJG_RS38220	COG3268	Saccharopine dehydrogenase
SHJG_RS38225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJG_RS38230	COG0183	Belongs to the thiolase family
SHJG_RS38235	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJG_RS38235	COG1024	Enoyl-CoA hydratase
SHJG_RS38245	COG1113	amino acid transport
SHJG_RS38250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJG_RS38265	COG2936	dipeptidyl-peptidase activity
SHJG_RS38275	COG0488	(ABC) transporter
SHJG_RS38280	COG2183	response to ionizing radiation
SHJG_RS38285	COG1024	Enoyl-CoA hydratase
SHJG_RS38295	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SHJG_RS38340	COG1134	teichoic acid transport
SHJG_RS38345	COG1562	ergosterol biosynthetic process
SHJG_RS38355	COG1233	COG1233 Phytoene dehydrogenase and related
SHJG_RS38365	COG1657	PFAM Prenyltransferase squalene oxidase
SHJG_RS38380	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SHJG_RS38385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SHJG_RS38415	COG2755	lipolytic protein G-D-S-L family
SHJG_RS38425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SHJG_RS38460	COG1063	alcohol dehydrogenase
SHJG_RS38465	COG0156	8-amino-7-oxononanoate synthase activity
SHJG_RS38470	COG0583	DNA-binding transcription factor activity
SHJG_RS38495	COG3958	Transketolase
SHJG_RS38500	COG3959	Transketolase, thiamine diphosphate binding domain
SHJG_RS38530	COG0561	phosphatase activity
SHJG_RS38550	COG0783	Belongs to the Dps family
SHJG_RS38555	COG2267	carboxylic ester hydrolase activity
SHJG_RS38560	COG0183	Belongs to the thiolase family
SHJG_RS38565	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS38575	COG0546	phosphoglycolate phosphatase activity
SHJG_RS38610	COG0726	polysaccharide deacetylase
SHJG_RS38625	COG1653	transport
SHJG_RS38630	COG1175	transmembrane transport
SHJG_RS38640	COG1472	Belongs to the glycosyl hydrolase 3 family
SHJG_RS38660	COG0395	ABC-type sugar transport system, permease component
SHJG_RS38665	COG1175	transmembrane transport
SHJG_RS38670	COG1653	transport
SHJG_RS38675	COG2188	Transcriptional regulator
SHJG_RS38705	COG0673	inositol 2-dehydrogenase activity
SHJG_RS38710	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS38720	COG1609	Transcriptional regulator
SHJG_RS38725	COG0673	inositol 2-dehydrogenase activity
SHJG_RS38730	COG1609	Transcriptional regulator
SHJG_RS38750	COG0477	Major facilitator Superfamily
SHJG_RS38770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJG_RS38775	COG3275	phosphorelay sensor kinase activity
SHJG_RS38780	COG0531	amino acid
SHJG_RS38790	COG3938	Belongs to the proline racemase family
SHJG_RS38795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJG_RS38800	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJG_RS38810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJG_RS38825	COG1126	abc transporter atp-binding protein
SHJG_RS38830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJG_RS38835	COG0456	acetyltransferase
SHJG_RS38840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS38845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS38850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS38860	COG2197	response regulator
SHJG_RS38890	COG2838	Isocitrate dehydrogenase
SHJG_RS38900	COG0668	transmembrane transport
SHJG_RS38905	COG0531	amino acid
SHJG_RS38915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SHJG_RS38930	COG1024	Enoyl-CoA hydratase
SHJG_RS38940	COG1132	(ABC) transporter
SHJG_RS38950	COG2080	2 iron, 2 sulfur cluster binding
SHJG_RS38955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SHJG_RS38960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SHJG_RS38990	COG1335	isochorismatase
SHJG_RS39020	COG0655	NAD(P)H dehydrogenase (quinone) activity
SHJG_RS39030	COG0477	Major facilitator Superfamily
SHJG_RS39040	COG0583	DNA-binding transcription factor activity
SHJG_RS39045	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS39050	COG1309	transcriptional regulator
SHJG_RS39085	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SHJG_RS39095	COG2815	serine threonine protein kinase
SHJG_RS39095	COG0515	serine threonine protein kinase
SHJG_RS39100	COG0515	serine threonine protein kinase
SHJG_RS39105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SHJG_RS39210	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SHJG_RS39210	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SHJG_RS39215	COG0210	DNA helicase
SHJG_RS39235	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SHJG_RS39245	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SHJG_RS39265	COG0297	glycogen (starch) synthase activity
SHJG_RS39270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SHJG_RS39275	COG3537	Alpha-1,2-mannosidase
SHJG_RS39305	COG2186	Transcriptional regulator
SHJG_RS39315	COG1129	ABC transporter
SHJG_RS39325	COG4948	Mandelate Racemase Muconate Lactonizing
SHJG_RS39360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SHJG_RS39385	COG0531	amino acid
SHJG_RS39400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SHJG_RS39400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SHJG_RS39405	COG0726	polysaccharide deacetylase
SHJG_RS39440	COG0583	DNA-binding transcription factor activity
SHJG_RS39450	COG0583	DNA-binding transcription factor activity
SHJG_RS39460	COG1053	succinate dehydrogenase
SHJG_RS39465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SHJG_RS39490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJG_RS39500	COG3360	Dodecin
SHJG_RS39505	COG2182	Extracellular solute-binding protein
SHJG_RS39510	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SHJG_RS39515	COG0121	glutamine amidotransferase
SHJG_RS39520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SHJG_RS39555	COG2268	Band 7 protein
SHJG_RS39600	COG1609	Transcriptional regulator
SHJG_RS39605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SHJG_RS39615	COG0242	peptide deformylase activity
SHJG_RS39625	COG1793	dna ligase
SHJG_RS39670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SHJG_RS39785	COG0210	DNA helicase
SHJG_RS39825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SHJG_RS39850	COG3328	transposase activity
SHJG_RS40025	COG3336	cytochrome c oxidase
SHJG_RS40040	COG0753	catalase activity
SHJG_RS40075	COG0745	RESPONSE REGULATOR receiver
SHJG_RS40080	COG5002	protein histidine kinase activity
SHJG_RS40090	COG1595	DNA-templated transcription, initiation
SHJG_RS40100	COG0395	ABC-type sugar transport system, permease component
SHJG_RS40105	COG1175	transmembrane transport
SHJG_RS40110	COG2182	Extracellular solute-binding protein
SHJG_RS40115	COG1501	Belongs to the glycosyl hydrolase 31 family
SHJG_RS40135	COG0753	catalase activity
SHJG_RS40155	COG0584	glycerophosphoryl diester phosphodiesterase
SHJG_RS40160	COG1785	Belongs to the alkaline phosphatase family
SHJG_RS40200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SHJG_RS40225	COG0542	response to heat
SHJG_RS40240	COG1174	glycine betaine transport
SHJG_RS40260	COG1556	Lactate utilization protein
SHJG_RS40265	COG1139	Iron-sulfur cluster binding protein
SHJG_RS40270	COG0247	lactate metabolic process
SHJG_RS40275	COG1070	Carbohydrate kinase
SHJG_RS40280	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS40280	COG3347	Dehydrogenase
SHJG_RS40290	COG1129	ABC transporter
SHJG_RS40295	COG1172	Belongs to the binding-protein-dependent transport system permease family
SHJG_RS40325	COG1609	Transcriptional regulator
SHJG_RS40335	COG1357	PFAM Pentapeptide repeats (8 copies)
SHJG_RS40345	COG1309	transcriptional regulator
SHJG_RS40360	COG2706	6-phosphogluconolactonase activity
SHJG_RS40415	COG0546	phosphoglycolate phosphatase activity
SHJG_RS40420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SHJG_RS40420	COG1796	DNA polymerase
SHJG_RS40425	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS40470	COG1006	Multisubunit Na H antiporter MnhC subunit
SHJG_RS40475	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJG_RS40520	COG0435	Glutathione S-transferase
SHJG_RS40540	COG2124	cytochrome p450
SHJG_RS40555	COG0667	Aldo Keto reductase
SHJG_RS40590	COG1595	DNA-templated transcription, initiation
SHJG_RS40600	COG3250	beta-galactosidase activity
SHJG_RS40640	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJG_RS40655	COG0300	oxidoreductase activity
SHJG_RS40665	COG0726	polysaccharide deacetylase
SHJG_RS40685	COG2274	protein secretion by the type I secretion system
SHJG_RS40720	COG2124	cytochrome p450
SHJG_RS40740	COG3251	PFAM MbtH domain protein
SHJG_RS40780	COG0477	Major facilitator Superfamily
SHJG_RS40790	COG0247	lactate metabolic process
SHJG_RS40790	COG0277	FAD linked oxidase domain protein
SHJG_RS40795	COG0300	oxidoreductase activity
SHJG_RS40820	COG0596	Alpha beta hydrolase
SHJG_RS40825	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS40835	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SHJG_RS40870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJG_RS40885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SHJG_RS40910	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS40915	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS40930	COG1940	carbohydrate kinase activity
SHJG_RS40930	COG1846	Transcriptional regulator
SHJG_RS40970	COG1309	transcriptional regulator
SHJG_RS40990	COG0367	asparagine synthase
SHJG_RS41065	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SHJG_RS41080	COG3387	PFAM Glycoside hydrolase 15-related
SHJG_RS41100	COG3290	protein histidine kinase activity
SHJG_RS41115	COG2045	Belongs to the ComB family
SHJG_RS41145	COG0456	acetyltransferase
SHJG_RS41220	COG0667	Aldo Keto reductase
SHJG_RS41230	COG2124	cytochrome p450
SHJG_RS41260	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SHJG_RS41285	COG0248	Ppx GppA phosphatase
SHJG_RS41315	COG1982	Orn Lys Arg decarboxylase major
SHJG_RS41335	COG2172	sigma factor antagonist activity
SHJG_RS41340	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJG_RS41345	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJG_RS41395	COG2197	response regulator
SHJG_RS41405	COG0583	DNA-binding transcription factor activity
SHJG_RS41430	COG0531	amino acid
SHJG_RS41445	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS41465	COG0596	Alpha beta hydrolase
SHJG_RS41475	COG0395	ABC-type sugar transport system, permease component
SHJG_RS41495	COG2267	carboxylic ester hydrolase activity
SHJG_RS41500	COG2755	lipolytic protein G-D-S-L family
SHJG_RS41510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SHJG_RS41525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJG_RS41550	COG1177	transmembrane transport
SHJG_RS41555	COG1176	ABC-type spermidine putrescine transport system, permease component I
SHJG_RS41560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SHJG_RS41565	COG3842	ATPase activity
SHJG_RS41580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SHJG_RS41585	COG1733	regulation of RNA biosynthetic process
SHJG_RS41630	COG0277	FAD linked oxidase domain protein
SHJG_RS41635	COG1597	lipid kinase activity
SHJG_RS41645	COG0542	response to heat
SHJG_RS41655	COG4106	trans-aconitate 2-methyltransferase activity
SHJG_RS41660	COG0640	Transcriptional regulator
SHJG_RS41665	COG1316	TRANSCRIPTIONal
SHJG_RS41685	COG2814	Major facilitator Superfamily
SHJG_RS41705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SHJG_RS41710	COG2409	Drug exporters of the RND superfamily
SHJG_RS41740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJG_RS41765	COG1175	transmembrane transport
SHJG_RS41770	COG2182	Extracellular solute-binding protein
SHJG_RS41795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SHJG_RS41800	COG1132	(ABC) transporter
SHJG_RS41810	COG1271	oxidase subunit
SHJG_RS41815	COG0783	Belongs to the Dps family
SHJG_RS41855	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SHJG_RS41855	COG3608	succinylglutamate desuccinylase aspartoacylase
SHJG_RS41860	COG0028	Belongs to the TPP enzyme family
SHJG_RS41875	COG3619	membrane
SHJG_RS41880	COG2259	Doxx family
SHJG_RS41885	COG1335	isochorismatase
SHJG_RS41890	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SHJG_RS41915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJG_RS41915	COG0515	serine threonine protein kinase
SHJG_RS41940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJG_RS41940	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SHJG_RS41970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJG_RS41980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SHJG_RS41985	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SHJG_RS41990	COG1082	Xylose isomerase domain protein TIM barrel
SHJG_RS42010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SHJG_RS42035	COG0326	Molecular chaperone. Has ATPase activity
SHJG_RS42065	COG0583	DNA-binding transcription factor activity
SHJG_RS42155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SHJG_RS42160	COG1120	ATPase activity
SHJG_RS42170	COG5640	endopeptidase activity
SHJG_RS42175	COG0583	DNA-binding transcription factor activity
SHJG_RS42185	COG3345	alpha-galactosidase
SHJG_RS42195	COG1175	transmembrane transport
SHJG_RS42200	COG0395	ABC-type sugar transport system, permease component
SHJG_RS42215	COG2186	Transcriptional regulator
SHJG_RS42220	COG4948	Mandelate Racemase Muconate Lactonizing
SHJG_RS42230	COG0800	Aldolase
SHJG_RS42235	COG3386	PFAM SMP-30 Gluconolaconase
SHJG_RS42250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SHJG_RS42255	COG0110	maltose O-acetyltransferase activity
SHJG_RS42260	COG0318	PFAM AMP-dependent synthetase and ligase
SHJG_RS42265	COG0492	ferredoxin-NADP+ reductase activity
SHJG_RS42280	COG0475	glutathione-regulated potassium exporter activity
SHJG_RS42310	COG0395	ABC-type sugar transport system, permease component
SHJG_RS42325	COG1609	Transcriptional regulator
SHJG_RS42330	COG0583	DNA-binding transcription factor activity
SHJG_RS42365	COG4249	Peptidase C14 caspase catalytic subunit p20
SHJG_RS42365	COG2319	Wd-40 repeat
SHJG_RS42405	COG2154	pterin-4-alpha-carbinolamine dehydratase
SHJG_RS42425	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS42445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJG_RS42450	COG1660	Displays ATPase and GTPase activities
SHJG_RS42460	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SHJG_RS42470	COG2226	methyltransferase
SHJG_RS42475	COG3623	hexulose-6-phosphate isomerase
SHJG_RS42495	COG1063	alcohol dehydrogenase
SHJG_RS42500	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SHJG_RS42520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SHJG_RS42530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SHJG_RS42550	COG0431	NADPH-dependent FMN reductase
SHJG_RS42585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJG_RS42615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SHJG_RS42685	COG3851	Histidine kinase
SHJG_RS42690	COG2197	response regulator
SHJG_RS42695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SHJG_RS42750	COG1733	regulation of RNA biosynthetic process
SHJG_RS42775	COG0583	DNA-binding transcription factor activity
SHJG_RS42790	COG1397	ADP-ribosylglycohydrolase
SHJG_RS42860	COG0596	Alpha beta hydrolase
SHJG_RS42865	COG1595	DNA-templated transcription, initiation
SHJG_RS42875	COG1278	Cold shock
SHJG_RS42920	COG2508	Transcriptional regulator
SHJG_RS42925	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS42935	COG0179	Fumarylacetoacetate (FAA) hydrolase
SHJG_RS42950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJG_RS42985	COG0671	phosphoesterase, PA-phosphatase related
SHJG_RS42990	COG0671	phosphoesterase, PA-phosphatase related
SHJG_RS43010	COG0305	Participates in initiation and elongation during chromosome replication
SHJG_RS43015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJG_RS43040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SHJG_RS43075	COG4585	Histidine kinase
SHJG_RS43080	COG2197	response regulator
SHJG_RS43090	COG2272	Belongs to the type-B carboxylesterase lipase family
SHJG_RS43105	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS43155	COG1028	Short-chain dehydrogenase reductase Sdr
SHJG_RS43210	COG0475	glutathione-regulated potassium exporter activity
SHJG_RS43225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SHJG_RS43245	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SHJG_RS43260	COG0477	Major facilitator Superfamily
SHJG_RS43265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SHJG_RS43300	COG1476	TRANSCRIPTIONal
SHJG_RS43305	COG3903	Transcriptional regulator
SHJG_RS43305	COG3629	intracellular signal transduction
SHJG_RS43330	COG0702	epimerase
SHJG_RS43355	COG0492	ferredoxin-NADP+ reductase activity
SHJG_RS43400	COG2814	Major facilitator Superfamily
SHJG_RS43405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SHJG_RS43420	COG5285	phytanoyl-CoA dioxygenase
SHJG_RS43445	COG2235	arginine
SHJG_RS43450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SHJG_RS43560	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SHJG_RS43585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SHJG_RS43610	COG2801	Transposase and inactivated derivatives
SHJG_RS43730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SHJG_RS43740	COG2233	PERMEase
SHJG_RS43750	COG0402	S-adenosylhomocysteine deaminase activity
SHJG_RS43770	COG3547	Transposase (IS116 IS110 IS902 family)
SHJG_RS43775	COG3547	Transposase (IS116 IS110 IS902 family)
SHJG_RS43855	COG0516	GMP reductase activity
SHJG_RS43855	COG0517	IMP dehydrogenase activity
SHJG_RS43885	COG1063	alcohol dehydrogenase
SHJG_RS43895	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJG_RS43900	COG0022	dehydrogenase e1 component
SHJG_RS43900	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJG_RS43905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SHJG_RS43910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJG_RS43960	COG0569	domain protein
SHJG_RS43965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SHJG_RS44000	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SHJG_RS44005	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SHJG_RS44070	COG0574	Belongs to the PEP-utilizing enzyme family
SHJG_RS44070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJG_RS44080	COG0517	IMP dehydrogenase activity
SHJG_RS44080	COG0516	GMP reductase activity
SHJG_RS44260	COG0477	Major facilitator Superfamily
SHJG_RS44285	COG3293	Transposase
SHJG_RS44385	COG0583	DNA-binding transcription factor activity
SHJG_RS45610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJG_RS45665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SHJG_RS45665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SHJG_RS45815	COG1028	Short-chain dehydrogenase reductase Sdr