locus-tag	class	description
SHJGH_RS00125	COG2801	Transposase and inactivated derivatives
SHJGH_RS00130	COG2963	transposase activity
SHJGH_RS00150	COG1902	pentaerythritol trinitrate reductase activity
SHJGH_RS00165	COG1475	DNA binding
SHJGH_RS00225	COG0484	heat shock protein binding
SHJGH_RS00290	COG3328	transposase activity
SHJGH_RS00315	COG1192	Involved in chromosome partitioning
SHJGH_RS00345	COG3415	Transposase
SHJGH_RS00345	COG2801	Transposase and inactivated derivatives
SHJGH_RS00390	COG3547	Transposase (IS116 IS110 IS902 family)
SHJGH_RS00415	COG3547	Transposase (IS116 IS110 IS902 family)
SHJGH_RS00445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SHJGH_RS00450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SHJGH_RS00480	COG3415	Transposase
SHJGH_RS00480	COG2801	Transposase and inactivated derivatives
SHJGH_RS00490	COG2826	transposase and inactivated derivatives, IS30 family
SHJGH_RS00525	COG2197	response regulator
SHJGH_RS00585	COG0596	Alpha beta hydrolase
SHJGH_RS00590	COG3629	intracellular signal transduction
SHJGH_RS00590	COG3903	Transcriptional regulator
SHJGH_RS00620	COG2801	Transposase and inactivated derivatives
SHJGH_RS00645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SHJGH_RS00650	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SHJGH_RS00660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SHJGH_RS00665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SHJGH_RS00685	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS00690	COG1216	Glycosyl transferase, family 2
SHJGH_RS00705	COG3387	PFAM Glycoside hydrolase 15-related
SHJGH_RS00770	COG5434	Belongs to the glycosyl hydrolase 28 family
SHJGH_RS00785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJGH_RS00790	COG2249	NAD(P)H dehydrogenase (quinone) activity
SHJGH_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS00825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SHJGH_RS00830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJGH_RS00835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJGH_RS00840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJGH_RS00880	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS00925	COG0604	alcohol dehydrogenase
SHJGH_RS00925	COG3321	synthase
SHJGH_RS00950	COG3540	Alkaline phosphatase
SHJGH_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS01060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SHJGH_RS01080	COG0488	(ABC) transporter
SHJGH_RS01085	COG0488	(ABC) transporter
SHJGH_RS01105	COG3903	Transcriptional regulator
SHJGH_RS01105	COG3629	intracellular signal transduction
SHJGH_RS01130	COG2801	Transposase and inactivated derivatives
SHJGH_RS01130	COG3415	Transposase
SHJGH_RS01160	COG1764	response to oxidative stress
SHJGH_RS01165	COG0242	peptide deformylase activity
SHJGH_RS01195	COG3415	Transposase
SHJGH_RS01195	COG2801	Transposase and inactivated derivatives
SHJGH_RS01240	COG0741	lytic transglycosylase activity
SHJGH_RS01245	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJGH_RS01300	COG1605	Chorismate mutase
SHJGH_RS01300	COG0077	Prephenate dehydratase
SHJGH_RS01325	COG0477	Major facilitator Superfamily
SHJGH_RS01450	COG2855	membrane
SHJGH_RS01465	COG0753	catalase activity
SHJGH_RS01495	COG2755	lipolytic protein G-D-S-L family
SHJGH_RS01520	COG2234	aminopeptidase activity
SHJGH_RS01545	COG0242	peptide deformylase activity
SHJGH_RS01570	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SHJGH_RS01585	COG2130	NADP-dependent
SHJGH_RS01600	COG1073	alpha beta
SHJGH_RS01615	COG1309	transcriptional regulator
SHJGH_RS01655	COG0513	Belongs to the DEAD box helicase family
SHJGH_RS01660	COG1278	Cold shock
SHJGH_RS01665	COG3903	Transcriptional regulator
SHJGH_RS01665	COG3629	intracellular signal transduction
SHJGH_RS01675	COG1073	alpha beta
SHJGH_RS01680	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SHJGH_RS01685	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS01690	COG2205	protein histidine kinase activity
SHJGH_RS01695	COG1686	Belongs to the peptidase S11 family
SHJGH_RS01725	COG2027	D-alanyl-D-alanine carboxypeptidase
SHJGH_RS01745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SHJGH_RS01750	COG0028	Belongs to the TPP enzyme family
SHJGH_RS01770	COG0577	efflux transmembrane transporter activity
SHJGH_RS01775	COG4585	Histidine kinase
SHJGH_RS01780	COG2197	response regulator
SHJGH_RS01795	COG2197	response regulator
SHJGH_RS01800	COG2197	response regulator
SHJGH_RS01825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SHJGH_RS01840	COG4166	transmembrane transport
SHJGH_RS01845	COG0601	transmembrane transport
SHJGH_RS01850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJGH_RS01860	COG4608	Belongs to the ABC transporter superfamily
SHJGH_RS01870	COG1192	Involved in chromosome partitioning
SHJGH_RS01885	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS01890	COG1175	transmembrane transport
SHJGH_RS01900	COG1609	Transcriptional regulator
SHJGH_RS01910	COG1136	(ABC) transporter
SHJGH_RS01910	COG0577	efflux transmembrane transporter activity
SHJGH_RS01915	COG0577	efflux transmembrane transporter activity
SHJGH_RS01915	COG1136	(ABC) transporter
SHJGH_RS01930	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS01935	COG5002	protein histidine kinase activity
SHJGH_RS01940	COG1309	transcriptional regulator
SHJGH_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS01950	COG0667	Aldo Keto reductase
SHJGH_RS01970	COG0667	Aldo Keto reductase
SHJGH_RS01980	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS01990	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS01995	COG2267	carboxylic ester hydrolase activity
SHJGH_RS02010	COG1271	oxidase subunit
SHJGH_RS02025	COG2837	iron assimilation
SHJGH_RS02065	COG0697	spore germination
SHJGH_RS02150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJGH_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS02165	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS02170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS02195	COG4555	ABC transporter
SHJGH_RS02250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJGH_RS02260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS02290	COG1131	(ABC) transporter
SHJGH_RS02310	COG2267	carboxylic ester hydrolase activity
SHJGH_RS02315	COG0535	radical SAM domain protein
SHJGH_RS02325	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
SHJGH_RS02330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SHJGH_RS02340	COG2133	pyrroloquinoline quinone binding
SHJGH_RS02390	COG0438	transferase activity, transferring glycosyl groups
SHJGH_RS02400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SHJGH_RS02405	COG1472	Belongs to the glycosyl hydrolase 3 family
SHJGH_RS02410	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS02450	COG0583	DNA-binding transcription factor activity
SHJGH_RS02455	COG0667	Aldo Keto reductase
SHJGH_RS02460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJGH_RS02465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SHJGH_RS02470	COG1993	acr, cog1993
SHJGH_RS02475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SHJGH_RS02500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SHJGH_RS02510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJGH_RS02525	COG4948	Mandelate Racemase Muconate Lactonizing
SHJGH_RS02535	COG1846	Transcriptional regulator
SHJGH_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS02575	COG0656	L-ascorbic acid biosynthetic process
SHJGH_RS02600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SHJGH_RS02605	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SHJGH_RS02610	COG2080	2 iron, 2 sulfur cluster binding
SHJGH_RS02630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SHJGH_RS02635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJGH_RS02645	COG1737	Transcriptional regulator
SHJGH_RS02650	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SHJGH_RS02705	COG1132	(ABC) transporter
SHJGH_RS02710	COG1937	Protein conserved in bacteria
SHJGH_RS02715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SHJGH_RS02715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJGH_RS02725	COG0730	response to heat
SHJGH_RS02730	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SHJGH_RS02745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SHJGH_RS02745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SHJGH_RS02750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SHJGH_RS02755	COG0254	rRNA binding
SHJGH_RS02760	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SHJGH_RS02790	COG3795	YCII-related domain
SHJGH_RS02795	COG4941	Belongs to the sigma-70 factor family
SHJGH_RS02870	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS02880	COG1172	Belongs to the binding-protein-dependent transport system permease family
SHJGH_RS02885	COG1129	ABC transporter
SHJGH_RS02890	COG1940	carbohydrate kinase activity
SHJGH_RS02925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS02940	COG2318	DinB family
SHJGH_RS03015	COG1846	Transcriptional regulator
SHJGH_RS03020	COG0477	Major facilitator Superfamily
SHJGH_RS03030	COG1309	transcriptional regulator
SHJGH_RS03105	COG2267	carboxylic ester hydrolase activity
SHJGH_RS03120	COG1335	isochorismatase
SHJGH_RS03130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS03150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJGH_RS03155	COG1024	Enoyl-CoA hydratase
SHJGH_RS03160	COG1024	Enoyl-CoA hydratase
SHJGH_RS03160	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJGH_RS03170	COG0604	alcohol dehydrogenase
SHJGH_RS03180	COG0596	Alpha beta hydrolase
SHJGH_RS03180	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJGH_RS03185	COG0583	DNA-binding transcription factor activity
SHJGH_RS03190	COG3903	Transcriptional regulator
SHJGH_RS03190	COG3629	intracellular signal transduction
SHJGH_RS03195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SHJGH_RS03210	COG2197	response regulator
SHJGH_RS03215	COG0583	DNA-binding transcription factor activity
SHJGH_RS03230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SHJGH_RS03230	COG0596	Alpha beta hydrolase
SHJGH_RS03230	COG2226	methyltransferase
SHJGH_RS03235	COG1672	PFAM Archaeal ATPase
SHJGH_RS03235	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJGH_RS03265	COG3383	formate dehydrogenase (NAD+) activity
SHJGH_RS03275	COG2197	response regulator
SHJGH_RS03285	COG2267	carboxylic ester hydrolase activity
SHJGH_RS03290	COG3903	Transcriptional regulator
SHJGH_RS03290	COG3629	intracellular signal transduction
SHJGH_RS03325	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS03330	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS03345	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SHJGH_RS03355	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SHJGH_RS03375	COG0254	rRNA binding
SHJGH_RS03380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SHJGH_RS03385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJGH_RS03395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJGH_RS03410	COG1335	isochorismatase
SHJGH_RS03435	COG0583	DNA-binding transcription factor activity
SHJGH_RS03445	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJGH_RS03445	COG1672	PFAM Archaeal ATPase
SHJGH_RS03470	COG0667	Aldo Keto reductase
SHJGH_RS03480	COG1733	regulation of RNA biosynthetic process
SHJGH_RS03485	COG0596	Alpha beta hydrolase
SHJGH_RS03485	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJGH_RS03490	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJGH_RS03490	COG1672	PFAM Archaeal ATPase
SHJGH_RS03505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SHJGH_RS03535	COG2814	Major facilitator Superfamily
SHJGH_RS03545	COG0656	L-ascorbic acid biosynthetic process
SHJGH_RS03550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS03560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SHJGH_RS03590	COG0765	amino acid transport
SHJGH_RS03600	COG1609	Transcriptional regulator
SHJGH_RS03605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJGH_RS03605	COG2022	thiamine diphosphate biosynthetic process
SHJGH_RS03610	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS03615	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJGH_RS03615	COG1902	pentaerythritol trinitrate reductase activity
SHJGH_RS03625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SHJGH_RS03635	COG1131	(ABC) transporter
SHJGH_RS03650	COG0142	geranyltranstransferase activity
SHJGH_RS03690	COG0477	Major facilitator Superfamily
SHJGH_RS03730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS03745	COG0583	DNA-binding transcription factor activity
SHJGH_RS03755	COG0431	NADPH-dependent FMN reductase
SHJGH_RS03765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS03830	COG0019	diaminopimelate decarboxylase activity
SHJGH_RS03845	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS03855	COG0546	phosphoglycolate phosphatase activity
SHJGH_RS03870	COG2271	Major facilitator Superfamily
SHJGH_RS03875	COG0583	DNA-binding transcription factor activity
SHJGH_RS03885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJGH_RS03955	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS03985	COG2814	Major facilitator Superfamily
SHJGH_RS04000	COG2267	carboxylic ester hydrolase activity
SHJGH_RS04075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJGH_RS04080	COG2188	Transcriptional regulator
SHJGH_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS04150	COG1349	DNA-binding transcription factor activity
SHJGH_RS04155	COG2223	nitrite transmembrane transporter activity
SHJGH_RS04175	COG3572	ergothioneine biosynthetic process
SHJGH_RS04180	COG2318	DinB family
SHJGH_RS04210	COG2353	YceI-like domain
SHJGH_RS04215	COG2353	YceI-like domain
SHJGH_RS04225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS04250	COG0596	Alpha beta hydrolase
SHJGH_RS04300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SHJGH_RS04310	COG2345	Transcriptional regulator
SHJGH_RS04325	COG0671	phosphoesterase, PA-phosphatase related
SHJGH_RS04335	COG3321	synthase
SHJGH_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS04335	COG0604	alcohol dehydrogenase
SHJGH_RS04340	COG0657	acetylesterase activity
SHJGH_RS04360	COG2814	Major facilitator Superfamily
SHJGH_RS04365	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS04370	COG0596	Alpha beta hydrolase
SHJGH_RS04435	COG3345	alpha-galactosidase
SHJGH_RS04445	COG3693	PFAM glycoside hydrolase, family 10
SHJGH_RS04460	COG2188	Transcriptional regulator
SHJGH_RS04480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SHJGH_RS04520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJGH_RS04525	COG0028	Belongs to the TPP enzyme family
SHJGH_RS04530	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS04605	COG0596	Alpha beta hydrolase
SHJGH_RS04635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SHJGH_RS04675	COG2814	Major facilitator Superfamily
SHJGH_RS04700	COG0583	DNA-binding transcription factor activity
SHJGH_RS04720	COG1131	(ABC) transporter
SHJGH_RS04725	COG4585	Histidine kinase
SHJGH_RS04730	COG2197	response regulator
SHJGH_RS04750	COG4221	oxidoreductase activity
SHJGH_RS04800	COG1301	dicarboxylic acid transport
SHJGH_RS04805	COG2828	Protein conserved in bacteria
SHJGH_RS04820	COG0596	Alpha beta hydrolase
SHJGH_RS04865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS04865	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS04865	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS04865	COG0300	oxidoreductase activity
SHJGH_RS04865	COG3321	synthase
SHJGH_RS04880	COG2175	clavaminate synthase activity
SHJGH_RS04905	COG3631	Ketosteroid isomerase-related protein
SHJGH_RS04920	COG1309	transcriptional regulator
SHJGH_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS04955	COG0583	DNA-binding transcription factor activity
SHJGH_RS04960	COG1309	transcriptional regulator
SHJGH_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS04970	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS05000	COG1309	transcriptional regulator
SHJGH_RS05010	COG3629	intracellular signal transduction
SHJGH_RS05010	COG3903	Transcriptional regulator
SHJGH_RS05015	COG0596	Alpha beta hydrolase
SHJGH_RS05025	COG0596	Alpha beta hydrolase
SHJGH_RS05045	COG0667	Aldo Keto reductase
SHJGH_RS05060	COG1309	transcriptional regulator
SHJGH_RS05080	COG0402	S-adenosylhomocysteine deaminase activity
SHJGH_RS05085	COG1733	regulation of RNA biosynthetic process
SHJGH_RS05090	COG2197	response regulator
SHJGH_RS05095	COG4585	Histidine kinase
SHJGH_RS05105	COG0577	efflux transmembrane transporter activity
SHJGH_RS05105	COG1136	(ABC) transporter
SHJGH_RS05145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJGH_RS05160	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SHJGH_RS05165	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS05190	COG2867	negative regulation of translational initiation
SHJGH_RS05200	COG0477	Major facilitator Superfamily
SHJGH_RS05205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJGH_RS05215	COG2867	negative regulation of translational initiation
SHJGH_RS05265	COG2814	Major facilitator Superfamily
SHJGH_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS05335	COG0596	Alpha beta hydrolase
SHJGH_RS05390	COG1609	Transcriptional regulator
SHJGH_RS05405	COG0179	Fumarylacetoacetate (FAA) hydrolase
SHJGH_RS05410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJGH_RS05415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJGH_RS05460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SHJGH_RS05465	COG3844	kynureninase activity
SHJGH_RS05475	COG3483	tryptophan 2,3-dioxygenase activity
SHJGH_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS05485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SHJGH_RS05490	COG2151	metal-sulfur cluster biosynthetic enzyme
SHJGH_RS05495	COG3396	Phenylacetate-CoA oxygenase
SHJGH_RS05505	COG3396	Phenylacetate-CoA oxygenase
SHJGH_RS05530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS05580	COG3479	Phenolic acid decarboxylase
SHJGH_RS05590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SHJGH_RS05605	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS05615	COG2186	Transcriptional regulator
SHJGH_RS05625	COG4948	Mandelate Racemase Muconate Lactonizing
SHJGH_RS05635	COG1175	transmembrane transport
SHJGH_RS05640	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS05665	COG0596	Alpha beta hydrolase
SHJGH_RS05670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SHJGH_RS05670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SHJGH_RS05690	COG3548	integral membrane protein
SHJGH_RS05710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SHJGH_RS05710	COG1017	nitric oxide dioxygenase activity
SHJGH_RS05760	COG0667	Aldo Keto reductase
SHJGH_RS05765	COG2207	Transcriptional regulator
SHJGH_RS05790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SHJGH_RS05805	COG1309	transcriptional regulator
SHJGH_RS05820	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS05825	COG1309	transcriptional regulator
SHJGH_RS05835	COG2124	cytochrome p450
SHJGH_RS05885	COG2175	clavaminate synthase activity
SHJGH_RS05890	COG0529	Catalyzes the synthesis of activated sulfate
SHJGH_RS05890	COG2046	Belongs to the sulfate adenylyltransferase family
SHJGH_RS05900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SHJGH_RS05925	COG0601	transmembrane transport
SHJGH_RS05935	COG0444	Belongs to the ABC transporter superfamily
SHJGH_RS05955	COG0477	Major facilitator Superfamily
SHJGH_RS05985	COG0300	oxidoreductase activity
SHJGH_RS06000	COG0657	acetylesterase activity
SHJGH_RS06010	COG2197	response regulator
SHJGH_RS06015	COG4585	Histidine kinase
SHJGH_RS06120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS06145	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS06160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJGH_RS06160	COG3320	Male sterility
SHJGH_RS06180	COG2175	clavaminate synthase activity
SHJGH_RS06185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SHJGH_RS06215	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SHJGH_RS06235	COG2963	transposase activity
SHJGH_RS06240	COG2801	Transposase and inactivated derivatives
SHJGH_RS06270	COG3293	Transposase
SHJGH_RS06295	COG2207	Transcriptional regulator
SHJGH_RS06310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SHJGH_RS06315	COG4977	sequence-specific DNA binding
SHJGH_RS06375	COG2801	Transposase and inactivated derivatives
SHJGH_RS06445	COG0747	negative chemotaxis
SHJGH_RS06465	COG2801	Transposase and inactivated derivatives
SHJGH_RS06480	COG1278	Cold shock
SHJGH_RS06490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJGH_RS06510	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS06560	COG0823	Involved in the tonB-independent uptake of proteins
SHJGH_RS06560	COG1506	peptidase
SHJGH_RS06640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SHJGH_RS06655	COG1454	alcohol dehydrogenase
SHJGH_RS06655	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS06680	COG0531	amino acid
SHJGH_RS06685	COG2235	arginine
SHJGH_RS06695	COG0549	Belongs to the carbamate kinase family
SHJGH_RS06725	COG2326	polyphosphate kinase activity
SHJGH_RS06740	COG4191	Histidine kinase
SHJGH_RS06755	COG0589	response to stress
SHJGH_RS06760	COG0574	Belongs to the PEP-utilizing enzyme family
SHJGH_RS06760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJGH_RS06765	COG0574	Belongs to the PEP-utilizing enzyme family
SHJGH_RS06765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJGH_RS06770	COG0574	Belongs to the PEP-utilizing enzyme family
SHJGH_RS06770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJGH_RS06775	COG0574	Belongs to the PEP-utilizing enzyme family
SHJGH_RS06775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJGH_RS06785	COG0659	secondary active sulfate transmembrane transporter activity
SHJGH_RS06805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJGH_RS06820	COG0009	L-threonylcarbamoyladenylate synthase
SHJGH_RS06825	COG4716	Myosin-crossreactive antigen
SHJGH_RS06900	COG2133	pyrroloquinoline quinone binding
SHJGH_RS06910	COG1278	Cold shock
SHJGH_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS06945	COG0604	alcohol dehydrogenase
SHJGH_RS06945	COG3321	synthase
SHJGH_RS06950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJGH_RS07000	COG2207	Transcriptional regulator
SHJGH_RS07090	COG0583	DNA-binding transcription factor activity
SHJGH_RS07125	COG1486	melibiose metabolic process
SHJGH_RS07130	COG1349	DNA-binding transcription factor activity
SHJGH_RS07135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJGH_RS07145	COG1175	transmembrane transport
SHJGH_RS07155	COG3250	beta-galactosidase activity
SHJGH_RS07200	COG3340	Belongs to the peptidase S51 family
SHJGH_RS07235	COG4865	methylaspartate mutase activity
SHJGH_RS07240	COG0017	Asparaginyl-tRNA synthetase
SHJGH_RS07250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJGH_RS07255	COG2423	ornithine cyclodeaminase activity
SHJGH_RS07285	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SHJGH_RS07295	COG0142	geranyltranstransferase activity
SHJGH_RS07325	COG2409	Drug exporters of the RND superfamily
SHJGH_RS07330	COG1846	Transcriptional regulator
SHJGH_RS07335	COG1335	isochorismatase
SHJGH_RS07400	COG0583	DNA-binding transcription factor activity
SHJGH_RS07410	COG0584	glycerophosphoryl diester phosphodiesterase
SHJGH_RS07445	COG3629	intracellular signal transduction
SHJGH_RS07445	COG3903	Transcriptional regulator
SHJGH_RS07460	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS07470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJGH_RS07475	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SHJGH_RS07480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJGH_RS07485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJGH_RS07500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SHJGH_RS07600	COG1733	regulation of RNA biosynthetic process
SHJGH_RS07605	COG0702	epimerase
SHJGH_RS07615	COG0028	Belongs to the TPP enzyme family
SHJGH_RS07620	COG3527	Alpha-acetolactate decarboxylase
SHJGH_RS07630	COG3842	ATPase activity
SHJGH_RS07640	COG1176	ABC-type spermidine putrescine transport system, permease component I
SHJGH_RS07645	COG1177	transmembrane transport
SHJGH_RS07655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJGH_RS07665	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS07670	COG2814	Major facilitator Superfamily
SHJGH_RS07705	COG0583	DNA-binding transcription factor activity
SHJGH_RS07710	COG0183	Belongs to the thiolase family
SHJGH_RS07720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SHJGH_RS07725	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJGH_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS07755	COG0586	Pfam SNARE associated Golgi protein
SHJGH_RS07765	COG0431	NADPH-dependent FMN reductase
SHJGH_RS07770	COG0583	DNA-binding transcription factor activity
SHJGH_RS07775	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS07805	COG1846	Transcriptional regulator
SHJGH_RS07810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SHJGH_RS07815	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS07825	COG1309	transcriptional regulator
SHJGH_RS07840	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS07845	COG4689	acetoacetate decarboxylase
SHJGH_RS07860	COG0174	glutamine synthetase
SHJGH_RS07885	COG0596	Alpha beta hydrolase
SHJGH_RS07920	COG1129	ABC transporter
SHJGH_RS07925	COG4211	Belongs to the binding-protein-dependent transport system permease family
SHJGH_RS07930	COG1172	Belongs to the binding-protein-dependent transport system permease family
SHJGH_RS07935	COG4948	Mandelate Racemase Muconate Lactonizing
SHJGH_RS07945	COG1940	carbohydrate kinase activity
SHJGH_RS07945	COG1846	Transcriptional regulator
SHJGH_RS07950	COG3345	alpha-galactosidase
SHJGH_RS07980	COG1063	alcohol dehydrogenase
SHJGH_RS08010	COG1063	alcohol dehydrogenase
SHJGH_RS08015	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SHJGH_RS08030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJGH_RS08040	COG4977	sequence-specific DNA binding
SHJGH_RS08055	COG2175	clavaminate synthase activity
SHJGH_RS08065	COG4521	taurine ABC transporter
SHJGH_RS08070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SHJGH_RS08075	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SHJGH_RS08095	COG2226	methyltransferase
SHJGH_RS08120	COG0655	NAD(P)H dehydrogenase (quinone) activity
SHJGH_RS08125	COG2226	methyltransferase
SHJGH_RS08130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SHJGH_RS08140	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SHJGH_RS08195	COG2234	aminopeptidase activity
SHJGH_RS08210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SHJGH_RS08225	COG1404	Belongs to the peptidase S8 family
SHJGH_RS08245	COG0477	Major facilitator Superfamily
SHJGH_RS08250	COG3250	beta-galactosidase activity
SHJGH_RS08260	COG0583	DNA-binding transcription factor activity
SHJGH_RS08270	COG0714	Associated with various cellular activities
SHJGH_RS08305	COG0596	Alpha beta hydrolase
SHJGH_RS08315	COG2267	carboxylic ester hydrolase activity
SHJGH_RS08320	COG2508	Transcriptional regulator
SHJGH_RS08345	COG0515	serine threonine protein kinase
SHJGH_RS08345	COG2815	serine threonine protein kinase
SHJGH_RS08400	COG2318	DinB family
SHJGH_RS08405	COG0583	DNA-binding transcription factor activity
SHJGH_RS08430	COG3973	AAA domain
SHJGH_RS08440	COG0604	alcohol dehydrogenase
SHJGH_RS08440	COG3321	synthase
SHJGH_RS08445	COG0604	alcohol dehydrogenase
SHJGH_RS08445	COG3321	synthase
SHJGH_RS08470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS08485	COG2267	carboxylic ester hydrolase activity
SHJGH_RS08495	COG2124	cytochrome p450
SHJGH_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS08515	COG2197	response regulator
SHJGH_RS08530	COG1136	(ABC) transporter
SHJGH_RS08530	COG0577	efflux transmembrane transporter activity
SHJGH_RS08540	COG0604	alcohol dehydrogenase
SHJGH_RS08540	COG3321	synthase
SHJGH_RS08570	COG4977	sequence-specific DNA binding
SHJGH_RS08615	COG3903	Transcriptional regulator
SHJGH_RS08615	COG3629	intracellular signal transduction
SHJGH_RS08620	COG3896	Chloramphenicol phosphotransferase-like protein
SHJGH_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS08640	COG1295	ribonuclease BN
SHJGH_RS08660	COG0701	Predicted permease
SHJGH_RS08675	COG1482	cell wall glycoprotein biosynthetic process
SHJGH_RS08710	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SHJGH_RS08735	COG0375	protein maturation
SHJGH_RS08750	COG0298	carbon dioxide binding
SHJGH_RS08755	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SHJGH_RS08765	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SHJGH_RS08770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SHJGH_RS08770	COG1024	Enoyl-CoA hydratase
SHJGH_RS08825	COG0640	Transcriptional regulator
SHJGH_RS08890	COG0667	Aldo Keto reductase
SHJGH_RS08910	COG0586	Pfam SNARE associated Golgi protein
SHJGH_RS08925	COG4999	Histidine kinase
SHJGH_RS08925	COG3850	Histidine kinase
SHJGH_RS08925	COG3437	response regulator, receiver
SHJGH_RS08925	COG2205	protein histidine kinase activity
SHJGH_RS08945	COG0437	4 iron, 4 sulfur cluster binding
SHJGH_RS08965	COG0243	molybdopterin cofactor binding
SHJGH_RS08965	COG3383	formate dehydrogenase (NAD+) activity
SHJGH_RS08970	COG3383	formate dehydrogenase (NAD+) activity
SHJGH_RS08970	COG0243	molybdopterin cofactor binding
SHJGH_RS08975	COG0709	Synthesizes selenophosphate from selenide and ATP
SHJGH_RS08980	COG0546	phosphoglycolate phosphatase activity
SHJGH_RS09000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SHJGH_RS09040	COG2267	carboxylic ester hydrolase activity
SHJGH_RS09065	COG0583	DNA-binding transcription factor activity
SHJGH_RS09155	COG0477	Major facilitator Superfamily
SHJGH_RS09165	COG0009	L-threonylcarbamoyladenylate synthase
SHJGH_RS09210	COG1621	beta-fructofuranosidase activity
SHJGH_RS09220	COG1175	transmembrane transport
SHJGH_RS09225	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS09230	COG1621	beta-fructofuranosidase activity
SHJGH_RS09235	COG1609	Transcriptional regulator
SHJGH_RS09240	COG0656	L-ascorbic acid biosynthetic process
SHJGH_RS09250	COG0667	Aldo Keto reductase
SHJGH_RS09300	COG1414	Transcriptional regulator
SHJGH_RS09305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SHJGH_RS09320	COG0181	hydroxymethylbilane synthase activity
SHJGH_RS09330	COG0842	Transport permease protein
SHJGH_RS09340	COG1846	Transcriptional regulator
SHJGH_RS09375	COG0366	Alpha amylase catalytic
SHJGH_RS09390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SHJGH_RS09395	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SHJGH_RS09415	COG1252	NADH dehydrogenase
SHJGH_RS09475	COG5002	protein histidine kinase activity
SHJGH_RS09515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJGH_RS09525	COG0589	response to stress
SHJGH_RS09560	COG3345	alpha-galactosidase
SHJGH_RS09565	COG1846	Transcriptional regulator
SHJGH_RS09565	COG1940	carbohydrate kinase activity
SHJGH_RS09595	COG3485	protocatechuate 3,4-dioxygenase
SHJGH_RS09620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJGH_RS09620	COG0515	serine threonine protein kinase
SHJGH_RS09625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS09635	COG3647	Membrane
SHJGH_RS09670	COG0328	RNA-DNA hybrid ribonuclease activity
SHJGH_RS09690	COG1396	sequence-specific DNA binding
SHJGH_RS09695	COG1191	sigma factor activity
SHJGH_RS09715	COG0667	Aldo Keto reductase
SHJGH_RS09720	COG0583	DNA-binding transcription factor activity
SHJGH_RS09730	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJGH_RS09735	COG0346	lactoylglutathione lyase activity
SHJGH_RS09750	COG0667	Aldo Keto reductase
SHJGH_RS09760	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS09785	COG0431	NADPH-dependent FMN reductase
SHJGH_RS09795	COG0702	epimerase
SHJGH_RS09820	COG3293	Transposase
SHJGH_RS09825	COG0531	amino acid
SHJGH_RS09830	COG1940	carbohydrate kinase activity
SHJGH_RS09835	COG3250	beta-galactosidase activity
SHJGH_RS09890	COG0367	asparagine synthase
SHJGH_RS09905	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS09925	COG0510	thiamine kinase activity
SHJGH_RS09960	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS09965	COG0596	Alpha beta hydrolase
SHJGH_RS09980	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS09985	COG2070	2-Nitropropane dioxygenase
SHJGH_RS09990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJGH_RS10020	COG0542	response to heat
SHJGH_RS10035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHJGH_RS10040	COG0443	Heat shock 70 kDa protein
SHJGH_RS10050	COG0047	phosphoribosylformylglycinamidine synthase activity
SHJGH_RS10060	COG0656	L-ascorbic acid biosynthetic process
SHJGH_RS10095	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS10150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SHJGH_RS10150	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SHJGH_RS10155	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SHJGH_RS10160	COG0297	glycogen (starch) synthase activity
SHJGH_RS10175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SHJGH_RS10185	COG2192	nodulation
SHJGH_RS10190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SHJGH_RS10210	COG2124	cytochrome p450
SHJGH_RS10230	COG2376	Dihydroxyacetone kinase
SHJGH_RS10235	COG1461	Dihydroxyacetone kinase
SHJGH_RS10265	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJGH_RS10265	COG1902	pentaerythritol trinitrate reductase activity
SHJGH_RS10300	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJGH_RS10320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SHJGH_RS10335	COG3458	cephalosporin-C deacetylase activity
SHJGH_RS10340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJGH_RS10345	COG2188	Transcriptional regulator
SHJGH_RS10350	COG2226	methyltransferase
SHJGH_RS10380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SHJGH_RS10395	COG2066	Belongs to the glutaminase family
SHJGH_RS10410	COG1113	amino acid transport
SHJGH_RS10415	COG2186	Transcriptional regulator
SHJGH_RS10420	COG1968	undecaprenyl-diphosphatase activity
SHJGH_RS10450	COG1175	transmembrane transport
SHJGH_RS10455	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS10470	COG0346	lactoylglutathione lyase activity
SHJGH_RS10480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SHJGH_RS10520	COG2340	Cysteine-rich secretory protein family
SHJGH_RS10525	COG1733	regulation of RNA biosynthetic process
SHJGH_RS10540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SHJGH_RS10570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJGH_RS10580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SHJGH_RS10630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SHJGH_RS10640	COG2124	cytochrome p450
SHJGH_RS10660	COG2814	Major facilitator Superfamily
SHJGH_RS10665	COG3548	integral membrane protein
SHJGH_RS10695	COG1917	Cupin 2, conserved barrel domain protein
SHJGH_RS10695	COG4977	sequence-specific DNA binding
SHJGH_RS10700	COG2814	Major facilitator Superfamily
SHJGH_RS10715	COG3903	Transcriptional regulator
SHJGH_RS10715	COG3629	intracellular signal transduction
SHJGH_RS10725	COG0805	protein transport
SHJGH_RS10780	COG0561	phosphatase activity
SHJGH_RS10790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS10810	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJGH_RS10810	COG2172	sigma factor antagonist activity
SHJGH_RS10810	COG2208	phosphoserine phosphatase activity
SHJGH_RS10830	COG3209	COG3209 Rhs family protein
SHJGH_RS10870	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SHJGH_RS10875	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SHJGH_RS10880	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SHJGH_RS10915	COG2197	response regulator
SHJGH_RS10930	COG0464	growth
SHJGH_RS11030	COG1971	Probably functions as a manganese efflux pump
SHJGH_RS11035	COG0535	radical SAM domain protein
SHJGH_RS11065	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SHJGH_RS11070	COG3284	Transcriptional regulator
SHJGH_RS11075	COG0563	adenylate kinase activity
SHJGH_RS11085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJGH_RS11115	COG0535	radical SAM domain protein
SHJGH_RS11145	COG2197	response regulator
SHJGH_RS11150	COG4585	Histidine kinase
SHJGH_RS11165	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS11180	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJGH_RS11180	COG0596	Alpha beta hydrolase
SHJGH_RS11185	COG0022	dehydrogenase e1 component
SHJGH_RS11190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SHJGH_RS11195	COG3199	ATP-NAD kinase
SHJGH_RS11200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SHJGH_RS11205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SHJGH_RS11215	COG1063	alcohol dehydrogenase
SHJGH_RS11225	COG0589	response to stress
SHJGH_RS11230	COG2706	6-phosphogluconolactonase activity
SHJGH_RS11240	COG3387	PFAM Glycoside hydrolase 15-related
SHJGH_RS11245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SHJGH_RS11250	COG3265	gluconokinase activity
SHJGH_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS11290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SHJGH_RS11295	COG1215	transferase activity, transferring glycosyl groups
SHJGH_RS11330	COG1349	DNA-binding transcription factor activity
SHJGH_RS11340	COG1024	Enoyl-CoA hydratase
SHJGH_RS11410	COG1619	proteins homologs of microcin C7 resistance protein MccF
SHJGH_RS11415	COG1940	carbohydrate kinase activity
SHJGH_RS11425	COG2813	Specifically methylates the guanine in position
SHJGH_RS11430	COG0191	fructose-bisphosphate aldolase activity
SHJGH_RS11435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SHJGH_RS11440	COG1349	DNA-binding transcription factor activity
SHJGH_RS11450	COG3579	cysteine-type endopeptidase activity
SHJGH_RS11475	COG2197	response regulator
SHJGH_RS11480	COG4585	Histidine kinase
SHJGH_RS11500	COG0445	tRNA wobble uridine modification
SHJGH_RS11510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJGH_RS11515	COG1660	Displays ATPase and GTPase activities
SHJGH_RS11525	COG3345	alpha-galactosidase
SHJGH_RS11545	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SHJGH_RS11590	COG0584	glycerophosphoryl diester phosphodiesterase
SHJGH_RS11620	COG2124	cytochrome p450
SHJGH_RS11650	COG0671	phosphoesterase, PA-phosphatase related
SHJGH_RS11675	COG2233	PERMEase
SHJGH_RS11680	COG0640	Transcriptional regulator
SHJGH_RS11685	COG1902	pentaerythritol trinitrate reductase activity
SHJGH_RS11690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SHJGH_RS11705	COG3509	depolymerase
SHJGH_RS11720	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS11740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SHJGH_RS11765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SHJGH_RS11770	COG0477	Major facilitator Superfamily
SHJGH_RS11790	COG0432	Pfam Uncharacterised protein family UPF0047
SHJGH_RS11795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SHJGH_RS11800	COG1116	anion transmembrane transporter activity
SHJGH_RS11810	COG2072	flavoprotein involved in K transport
SHJGH_RS11815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SHJGH_RS11820	COG1132	(ABC) transporter
SHJGH_RS11825	COG1846	Transcriptional regulator
SHJGH_RS11850	COG1132	(ABC) transporter
SHJGH_RS11860	COG0254	rRNA binding
SHJGH_RS11875	COG1946	Acyl-CoA thioesterase
SHJGH_RS11885	COG2018	Roadblock/LC7 domain
SHJGH_RS11910	COG3547	Transposase (IS116 IS110 IS902 family)
SHJGH_RS11965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SHJGH_RS11990	COG1846	Transcriptional regulator
SHJGH_RS11990	COG1940	carbohydrate kinase activity
SHJGH_RS11995	COG1113	amino acid transport
SHJGH_RS12015	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS12025	COG1942	4-Oxalocrotonate Tautomerase
SHJGH_RS12030	COG0586	Pfam SNARE associated Golgi protein
SHJGH_RS12065	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS12070	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS12085	COG3118	belongs to the thioredoxin family
SHJGH_RS12085	COG0492	ferredoxin-NADP+ reductase activity
SHJGH_RS12090	COG1793	dna ligase
SHJGH_RS12110	COG3424	synthase
SHJGH_RS12115	COG2124	cytochrome p450
SHJGH_RS12125	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS12135	COG0242	peptide deformylase activity
SHJGH_RS12145	COG3442	glutamine amidotransferase
SHJGH_RS12150	COG0205	6-phosphofructokinase activity
SHJGH_RS12165	COG1522	sequence-specific DNA binding
SHJGH_RS12170	COG1834	amidinotransferase
SHJGH_RS12175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SHJGH_RS12195	COG0204	Acyl-transferase
SHJGH_RS12210	COG0829	nickel cation binding
SHJGH_RS12215	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SHJGH_RS12220	COG0830	nickel cation binding
SHJGH_RS12225	COG0804	urea catabolic process
SHJGH_RS12230	COG0832	Belongs to the urease beta subunit family
SHJGH_RS12235	COG0831	urea catabolic process
SHJGH_RS12245	COG0740	serine-type endopeptidase activity
SHJGH_RS12275	COG0156	8-amino-7-oxononanoate synthase activity
SHJGH_RS12280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SHJGH_RS12285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SHJGH_RS12290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SHJGH_RS12295	COG2226	methyltransferase
SHJGH_RS12315	COG0456	acetyltransferase
SHJGH_RS12335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SHJGH_RS12340	COG3663	DNA glycosylase
SHJGH_RS12360	COG4585	Histidine kinase
SHJGH_RS12365	COG2197	response regulator
SHJGH_RS12370	COG1940	carbohydrate kinase activity
SHJGH_RS12380	COG1595	DNA-templated transcription, initiation
SHJGH_RS12405	COG0626	cystathionine gamma-synthase activity
SHJGH_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS12445	COG4585	Histidine kinase
SHJGH_RS12470	COG1522	sequence-specific DNA binding
SHJGH_RS12480	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SHJGH_RS12485	COG0419	ATPase involved in DNA repair
SHJGH_RS12490	COG0420	3'-5' exonuclease activity
SHJGH_RS12495	COG1739	Uncharacterized protein family UPF0029
SHJGH_RS12510	COG1832	CoA-binding protein
SHJGH_RS12525	COG0640	Transcriptional regulator
SHJGH_RS12590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SHJGH_RS12605	COG0183	Belongs to the thiolase family
SHJGH_RS12615	COG1968	undecaprenyl-diphosphatase activity
SHJGH_RS12630	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SHJGH_RS12645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SHJGH_RS12650	COG0747	negative chemotaxis
SHJGH_RS12695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SHJGH_RS12740	COG0697	spore germination
SHJGH_RS12805	COG3507	Belongs to the glycosyl hydrolase 43 family
SHJGH_RS12830	COG0725	ABC transporter, periplasmic molybdate-binding protein
SHJGH_RS12850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SHJGH_RS12850	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SHJGH_RS12860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SHJGH_RS12880	COG1716	ATPase activity
SHJGH_RS12900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SHJGH_RS12930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJGH_RS12940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJGH_RS12975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SHJGH_RS12980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SHJGH_RS13000	COG2018	Roadblock/LC7 domain
SHJGH_RS13015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJGH_RS13020	COG2146	nitrite reductase [NAD(P)H] activity
SHJGH_RS13025	COG1414	Transcriptional regulator
SHJGH_RS13045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJGH_RS13050	COG4638	Rieske (2fe-2S)
SHJGH_RS13055	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS13090	COG2814	Major facilitator Superfamily
SHJGH_RS13095	COG4336	lyase activity
SHJGH_RS13100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SHJGH_RS13105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SHJGH_RS13110	COG1984	allophanate hydrolase subunit 2
SHJGH_RS13120	COG0438	transferase activity, transferring glycosyl groups
SHJGH_RS13155	COG2364	Membrane
SHJGH_RS13165	COG2270	Major facilitator Superfamily
SHJGH_RS13175	COG3030	protein affecting phage T7 exclusion by the F plasmid
SHJGH_RS13180	COG0463	Glycosyl transferase, family 2
SHJGH_RS13200	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS13255	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SHJGH_RS13260	COG0140	phosphoribosyl-ATP diphosphatase activity
SHJGH_RS13265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SHJGH_RS13270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SHJGH_RS13270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SHJGH_RS13275	COG3201	nicotinamide mononucleotide transporter
SHJGH_RS13290	COG1846	Transcriptional regulator
SHJGH_RS13290	COG1940	carbohydrate kinase activity
SHJGH_RS13295	COG0738	Major facilitator superfamily
SHJGH_RS13310	COG2233	PERMEase
SHJGH_RS13325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SHJGH_RS13335	COG0531	amino acid
SHJGH_RS13360	COG2390	Transcriptional regulator
SHJGH_RS13365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SHJGH_RS13375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SHJGH_RS13390	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SHJGH_RS13405	COG0194	GDP metabolic process
SHJGH_RS13415	COG0284	orotidine-5'-phosphate decarboxylase activity
SHJGH_RS13420	COG0167	dihydroorotate dehydrogenase activity
SHJGH_RS13425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SHJGH_RS13430	COG0505	Belongs to the CarA family
SHJGH_RS13440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SHJGH_RS13445	COG0540	Belongs to the ATCase OTCase family
SHJGH_RS13450	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SHJGH_RS13460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SHJGH_RS13465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SHJGH_RS13470	COG0006	proline dipeptidase activity
SHJGH_RS13480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SHJGH_RS13485	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SHJGH_RS13490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SHJGH_RS13495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SHJGH_RS13505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SHJGH_RS13510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SHJGH_RS13530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SHJGH_RS13545	COG0124	histidyl-tRNA synthetase
SHJGH_RS13555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SHJGH_RS13560	COG1196	nuclear chromosome segregation
SHJGH_RS13565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SHJGH_RS13570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SHJGH_RS13575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SHJGH_RS13580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SHJGH_RS13590	COG2255	four-way junction helicase activity
SHJGH_RS13595	COG0632	four-way junction helicase activity
SHJGH_RS13600	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SHJGH_RS13605	COG0217	transcriptional regulatory protein
SHJGH_RS13610	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SHJGH_RS13615	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SHJGH_RS13625	COG0438	transferase activity, transferring glycosyl groups
SHJGH_RS13630	COG1560	Kdo2-lipid A biosynthetic process
SHJGH_RS13635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SHJGH_RS13655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SHJGH_RS13670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SHJGH_RS13725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SHJGH_RS13780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SHJGH_RS13780	COG1648	precorrin-2 dehydrogenase activity
SHJGH_RS13785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SHJGH_RS13810	COG1464	Belongs to the NlpA lipoprotein family
SHJGH_RS13815	COG2011	ABC-type metal ion transport system permease component
SHJGH_RS13820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SHJGH_RS13850	COG0204	Acyl-transferase
SHJGH_RS13850	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS13855	COG2132	Multicopper oxidase
SHJGH_RS13860	COG0477	Major facilitator Superfamily
SHJGH_RS13875	COG0165	Argininosuccinate lyase
SHJGH_RS13880	COG0137	argininosuccinate synthase activity
SHJGH_RS13900	COG2205	protein histidine kinase activity
SHJGH_RS13905	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS13945	COG1438	arginine binding
SHJGH_RS13950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SHJGH_RS13955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SHJGH_RS13960	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SHJGH_RS13965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SHJGH_RS13975	COG0463	Glycosyl transferase, family 2
SHJGH_RS14030	COG1649	PFAM Uncharacterised BCR, COG1649
SHJGH_RS14060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SHJGH_RS14060	COG0072	phenylalanine-tRNA ligase activity
SHJGH_RS14065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SHJGH_RS14070	COG5002	protein histidine kinase activity
SHJGH_RS14075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SHJGH_RS14080	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SHJGH_RS14085	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SHJGH_RS14090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SHJGH_RS14135	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS14140	COG0174	glutamine synthetase
SHJGH_RS14150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SHJGH_RS14175	COG4176	ABC-type proline glycine betaine transport system permease component
SHJGH_RS14180	COG4175	Glycine betaine
SHJGH_RS14180	COG0517	IMP dehydrogenase activity
SHJGH_RS14185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SHJGH_RS14200	COG0564	pseudouridine synthase activity
SHJGH_RS14240	COG0805	protein transport
SHJGH_RS14245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SHJGH_RS14280	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SHJGH_RS14290	COG1609	Transcriptional regulator
SHJGH_RS14295	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SHJGH_RS14300	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SHJGH_RS14315	COG4122	O-methyltransferase activity
SHJGH_RS14320	COG1222	aaa ATPase
SHJGH_RS14340	COG0517	IMP dehydrogenase activity
SHJGH_RS14340	COG1994	Peptidase M50
SHJGH_RS14350	COG2197	response regulator
SHJGH_RS14355	COG0747	negative chemotaxis
SHJGH_RS14365	COG0646	methionine synthase
SHJGH_RS14365	COG1410	methionine synthase
SHJGH_RS14370	COG1414	Transcriptional regulator
SHJGH_RS14375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SHJGH_RS14380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SHJGH_RS14385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SHJGH_RS14390	COG2186	Transcriptional regulator
SHJGH_RS14400	COG0215	cysteine-tRNA ligase activity
SHJGH_RS14420	COG0598	Magnesium transport protein CorA
SHJGH_RS14430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS14435	COG0667	Aldo Keto reductase
SHJGH_RS14460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJGH_RS14470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SHJGH_RS14470	COG1796	DNA polymerase
SHJGH_RS14490	COG3012	SEC-C Motif Domain Protein
SHJGH_RS14495	COG2186	Transcriptional regulator
SHJGH_RS14500	COG3265	gluconokinase activity
SHJGH_RS14510	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS14515	COG1063	alcohol dehydrogenase
SHJGH_RS14540	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SHJGH_RS14545	COG2149	membrane
SHJGH_RS14575	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS14585	COG3876	Protein conserved in bacteria
SHJGH_RS14620	COG0789	Transcriptional regulator
SHJGH_RS14640	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS14650	COG0640	Transcriptional regulator
SHJGH_RS14680	COG2851	Citrate transporter
SHJGH_RS14685	COG0243	molybdopterin cofactor binding
SHJGH_RS14690	COG1309	transcriptional regulator
SHJGH_RS14700	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SHJGH_RS14705	COG2188	Transcriptional regulator
SHJGH_RS14745	COG1595	DNA-templated transcription, initiation
SHJGH_RS14765	COG2755	lipolytic protein G-D-S-L family
SHJGH_RS14780	COG1725	Transcriptional regulator
SHJGH_RS14805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SHJGH_RS14810	COG0587	DNA-directed DNA polymerase activity
SHJGH_RS14835	COG1126	abc transporter atp-binding protein
SHJGH_RS14845	COG0765	amino acid transport
SHJGH_RS14875	COG1799	cell septum assembly
SHJGH_RS14880	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS14885	COG0477	Major facilitator Superfamily
SHJGH_RS14895	COG0671	phosphoesterase, PA-phosphatase related
SHJGH_RS14905	COG1652	LysM domain
SHJGH_RS14920	COG1160	GTP binding
SHJGH_RS14930	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SHJGH_RS14955	COG3541	Predicted nucleotidyltransferase
SHJGH_RS14960	COG1397	ADP-ribosylglycohydrolase
SHJGH_RS14965	COG1187	pseudouridine synthase activity
SHJGH_RS14970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SHJGH_RS14975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SHJGH_RS14990	COG0686	Belongs to the AlaDH PNT family
SHJGH_RS15000	COG0494	nUDIX hydrolase
SHJGH_RS15005	COG0504	CTP synthase activity
SHJGH_RS15010	COG3387	PFAM Glycoside hydrolase 15-related
SHJGH_RS15025	COG0297	glycogen (starch) synthase activity
SHJGH_RS15035	COG0497	DNA recombination
SHJGH_RS15040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SHJGH_RS15060	COG1120	ATPase activity
SHJGH_RS15065	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SHJGH_RS15070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SHJGH_RS15075	COG0647	UMP catabolic process
SHJGH_RS15110	COG2094	Belongs to the DNA glycosylase MPG family
SHJGH_RS15120	COG1881	PFAM PEBP family protein
SHJGH_RS15140	COG1119	ATPase activity
SHJGH_RS15160	COG2197	response regulator
SHJGH_RS15165	COG3850	Histidine kinase
SHJGH_RS15185	COG1131	(ABC) transporter
SHJGH_RS15185	COG1716	ATPase activity
SHJGH_RS15185	COG0842	Transport permease protein
SHJGH_RS15190	COG0560	Phosphoserine phosphatase
SHJGH_RS15190	COG3830	Belongs to the UPF0237 family
SHJGH_RS15210	COG2186	Transcriptional regulator
SHJGH_RS15240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SHJGH_RS15260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SHJGH_RS15265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJGH_RS15280	COG1404	Belongs to the peptidase S8 family
SHJGH_RS15285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJGH_RS15290	COG1063	alcohol dehydrogenase
SHJGH_RS15305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SHJGH_RS15320	COG3387	PFAM Glycoside hydrolase 15-related
SHJGH_RS15370	COG0488	(ABC) transporter
SHJGH_RS15390	COG2267	carboxylic ester hydrolase activity
SHJGH_RS15395	COG0235	Class ii aldolase
SHJGH_RS15415	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SHJGH_RS15420	COG1492	cobalamin metabolic process
SHJGH_RS15440	COG1797	cobyrinic acid a,c-diamide synthase activity
SHJGH_RS15475	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
SHJGH_RS15500	COG0765	amino acid transport
SHJGH_RS15505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJGH_RS15510	COG1104	cysteine desulfurase activity
SHJGH_RS15515	COG0456	acetyltransferase
SHJGH_RS15520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SHJGH_RS15525	COG1917	Cupin 2, conserved barrel domain protein
SHJGH_RS15530	COG5285	phytanoyl-CoA dioxygenase
SHJGH_RS15560	COG1414	Transcriptional regulator
SHJGH_RS15575	COG2252	PERMEase
SHJGH_RS15585	COG2186	Transcriptional regulator
SHJGH_RS15620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJGH_RS15625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SHJGH_RS15630	COG1349	DNA-binding transcription factor activity
SHJGH_RS15645	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS15650	COG1063	alcohol dehydrogenase
SHJGH_RS15660	COG1309	transcriptional regulator
SHJGH_RS15700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJGH_RS15705	COG2171	N-acyltransferase activity
SHJGH_RS15710	COG3226	Transcriptional regulator
SHJGH_RS15715	COG2076	Multidrug Resistance protein
SHJGH_RS15720	COG2151	metal-sulfur cluster biosynthetic enzyme
SHJGH_RS15725	COG0822	iron-sulfur transferase activity
SHJGH_RS15730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SHJGH_RS15735	COG0396	ATPase activity
SHJGH_RS15745	COG0719	Fe-S assembly protein
SHJGH_RS15760	COG2746	aminoglycoside 3-N-acetyltransferase activity
SHJGH_RS15765	COG1131	(ABC) transporter
SHJGH_RS15775	COG1612	heme a metabolic process
SHJGH_RS15795	COG0109	protoheme IX farnesyltransferase activity
SHJGH_RS15805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SHJGH_RS15820	COG0363	glucosamine-6-phosphate deaminase activity
SHJGH_RS15825	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS15830	COG1175	transmembrane transport
SHJGH_RS15835	COG1653	transport
SHJGH_RS15840	COG0366	Alpha amylase catalytic
SHJGH_RS15845	COG1653	transport
SHJGH_RS15850	COG1695	Transcriptional regulator
SHJGH_RS15855	COG1136	(ABC) transporter
SHJGH_RS15865	COG0166	Belongs to the GPI family
SHJGH_RS15880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SHJGH_RS15885	COG0149	triose-phosphate isomerase activity
SHJGH_RS15890	COG0126	phosphoglycerate kinase activity
SHJGH_RS15895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SHJGH_RS15905	COG1481	regulation of sporulation
SHJGH_RS15910	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SHJGH_RS15915	COG1660	Displays ATPase and GTPase activities
SHJGH_RS15920	COG0322	excinuclease ABC activity
SHJGH_RS15935	COG1609	Transcriptional regulator
SHJGH_RS15945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SHJGH_RS15960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJGH_RS15965	COG0765	amino acid transport
SHJGH_RS15975	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SHJGH_RS15980	COG0477	Major facilitator Superfamily
SHJGH_RS15985	COG0387	Pfam Sodium calcium exchanger
SHJGH_RS16005	COG0556	nucleotide-excision repair
SHJGH_RS16015	COG0584	glycerophosphoryl diester phosphodiesterase
SHJGH_RS16020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SHJGH_RS16030	COG2313	pseudouridylate synthase activity
SHJGH_RS16035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SHJGH_RS16035	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SHJGH_RS16040	COG2226	methyltransferase
SHJGH_RS16045	COG0598	Magnesium transport protein CorA
SHJGH_RS16070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJGH_RS16075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SHJGH_RS16105	COG1132	(ABC) transporter
SHJGH_RS16140	COG1953	Uracil, thiamine, allantoin
SHJGH_RS16145	COG1802	Transcriptional regulator
SHJGH_RS16165	COG2226	methyltransferase
SHJGH_RS16185	COG0237	dephospho-CoA kinase activity
SHJGH_RS16200	COG0539	negative regulation of cytoplasmic translation
SHJGH_RS16210	COG1643	Atp-dependent helicase
SHJGH_RS16245	COG2050	protein possibly involved in aromatic compounds catabolism
SHJGH_RS16305	COG0737	Belongs to the 5'-nucleotidase family
SHJGH_RS16325	COG0287	Prephenate dehydrogenase
SHJGH_RS16325	COG1605	Chorismate mutase
SHJGH_RS16345	COG0183	Belongs to the thiolase family
SHJGH_RS16350	COG1309	transcriptional regulator
SHJGH_RS16360	COG2304	oxidoreductase activity
SHJGH_RS16370	COG0070	glutamate synthase
SHJGH_RS16370	COG0069	glutamate synthase activity
SHJGH_RS16370	COG0067	glutamate synthase
SHJGH_RS16380	COG1397	ADP-ribosylglycohydrolase
SHJGH_RS16400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJGH_RS16405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJGH_RS16410	COG2301	Belongs to the HpcH HpaI aldolase family
SHJGH_RS16415	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SHJGH_RS16425	COG0159	tryptophan synthase activity
SHJGH_RS16430	COG0133	tryptophan synthase activity
SHJGH_RS16435	COG0134	indole-3-glycerol-phosphate synthase activity
SHJGH_RS16455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SHJGH_RS16460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SHJGH_RS16485	COG0107	imidazoleglycerol-phosphate synthase activity
SHJGH_RS16490	COG0251	oxidation-reduction process
SHJGH_RS16495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SHJGH_RS16500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SHJGH_RS16510	COG0131	Imidazoleglycerol-phosphate dehydratase
SHJGH_RS16515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJGH_RS16520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SHJGH_RS16540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SHJGH_RS16560	COG1432	Conserved Protein
SHJGH_RS16565	COG0587	DNA-directed DNA polymerase activity
SHJGH_RS16620	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SHJGH_RS16630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SHJGH_RS16635	COG3599	regulation of cell shape
SHJGH_RS16645	COG1799	cell septum assembly
SHJGH_RS16655	COG1496	oxidoreductase activity
SHJGH_RS16660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SHJGH_RS16670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SHJGH_RS16680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SHJGH_RS16685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SHJGH_RS16690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SHJGH_RS16695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SHJGH_RS16700	COG0768	penicillin binding
SHJGH_RS16710	COG0275	rRNA processing
SHJGH_RS16720	COG0714	Associated with various cellular activities
SHJGH_RS16740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SHJGH_RS16750	COG1126	abc transporter atp-binding protein
SHJGH_RS16760	COG1309	transcriptional regulator
SHJGH_RS16785	COG0352	thiamine-phosphate diphosphorylase activity
SHJGH_RS16805	COG2022	thiamine diphosphate biosynthetic process
SHJGH_RS16805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJGH_RS16815	COG2022	thiamine diphosphate biosynthetic process
SHJGH_RS16820	COG2815	serine threonine protein kinase
SHJGH_RS16820	COG0515	serine threonine protein kinase
SHJGH_RS16825	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SHJGH_RS16835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SHJGH_RS16840	COG2193	ferroxidase activity
SHJGH_RS16850	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SHJGH_RS16860	COG0205	6-phosphofructokinase activity
SHJGH_RS16895	COG1940	carbohydrate kinase activity
SHJGH_RS16905	COG0003	Pfam Anion-transporting ATPase
SHJGH_RS16980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SHJGH_RS16985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SHJGH_RS16990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SHJGH_RS16995	COG0723	plastoquinol--plastocyanin reductase activity
SHJGH_RS17000	COG2010	Cytochrome c
SHJGH_RS17005	COG1845	cytochrome c oxidase, subunit III
SHJGH_RS17015	COG1376	ErfK ybiS ycfS ynhG family protein
SHJGH_RS17025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJGH_RS17030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SHJGH_RS17040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJGH_RS17060	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SHJGH_RS17065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SHJGH_RS17070	COG2197	response regulator
SHJGH_RS17075	COG4585	Histidine kinase
SHJGH_RS17100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SHJGH_RS17120	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SHJGH_RS17125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SHJGH_RS17125	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SHJGH_RS17140	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SHJGH_RS17145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SHJGH_RS17150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SHJGH_RS17165	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SHJGH_RS17215	COG0321	lipoyl(octanoyl) transferase activity
SHJGH_RS17220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SHJGH_RS17250	COG2867	negative regulation of translational initiation
SHJGH_RS17255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJGH_RS17260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJGH_RS17270	COG0662	Cupin 2, conserved barrel domain protein
SHJGH_RS17290	COG0174	glutamine synthetase
SHJGH_RS17295	COG1335	isochorismatase
SHJGH_RS17315	COG0501	Belongs to the peptidase M48B family
SHJGH_RS17355	COG2267	carboxylic ester hydrolase activity
SHJGH_RS17370	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS17440	COG0366	Alpha amylase catalytic
SHJGH_RS17445	COG3833	ABC-type maltose transport systems, permease component
SHJGH_RS17450	COG1175	transmembrane transport
SHJGH_RS17460	COG1609	Transcriptional regulator
SHJGH_RS17470	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SHJGH_RS17480	COG3511	phospholipase C
SHJGH_RS17500	COG0174	glutamine synthetase
SHJGH_RS17510	COG1959	2 iron, 2 sulfur cluster binding
SHJGH_RS17555	COG2814	Major facilitator Superfamily
SHJGH_RS17570	COG0477	Major facilitator Superfamily
SHJGH_RS17575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SHJGH_RS17600	COG1994	Peptidase M50
SHJGH_RS17660	COG2837	iron assimilation
SHJGH_RS17665	COG0672	)-iron permease
SHJGH_RS17690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJGH_RS17695	COG2814	Major facilitator Superfamily
SHJGH_RS17710	COG1686	Belongs to the peptidase S11 family
SHJGH_RS17725	COG2259	Doxx family
SHJGH_RS17745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SHJGH_RS17770	COG0557	exoribonuclease II activity
SHJGH_RS17775	COG3022	response to hydroperoxide
SHJGH_RS17780	COG0800	Aldolase
SHJGH_RS17795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SHJGH_RS17805	COG2030	dehydratase
SHJGH_RS17810	COG4585	Histidine kinase
SHJGH_RS17825	COG2197	response regulator
SHJGH_RS17840	COG0477	Major facilitator Superfamily
SHJGH_RS17850	COG2247	cell wall binding repeat
SHJGH_RS17850	COG0860	N-Acetylmuramoyl-L-alanine amidase
SHJGH_RS17885	COG0438	transferase activity, transferring glycosyl groups
SHJGH_RS17890	COG1309	transcriptional regulator
SHJGH_RS17920	COG1657	PFAM Prenyltransferase squalene oxidase
SHJGH_RS17935	COG3845	ABC transporter
SHJGH_RS17955	COG3619	membrane
SHJGH_RS17960	COG2124	cytochrome p450
SHJGH_RS17965	COG0183	Belongs to the thiolase family
SHJGH_RS17980	COG4122	O-methyltransferase activity
SHJGH_RS18020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SHJGH_RS18090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJGH_RS18100	COG1358	cellular component organization or biogenesis
SHJGH_RS18145	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SHJGH_RS18150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SHJGH_RS18160	COG0477	Major facilitator Superfamily
SHJGH_RS18165	COG1309	transcriptional regulator
SHJGH_RS18180	COG0789	Transcriptional regulator
SHJGH_RS18195	COG1741	Belongs to the pirin family
SHJGH_RS18210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJGH_RS18215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJGH_RS18220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJGH_RS18255	COG2130	NADP-dependent
SHJGH_RS18260	COG1764	response to oxidative stress
SHJGH_RS18300	COG4214	carbohydrate transport
SHJGH_RS18310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJGH_RS18350	COG3386	PFAM SMP-30 Gluconolaconase
SHJGH_RS18355	COG1414	Transcriptional regulator
SHJGH_RS18380	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS18385	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SHJGH_RS18385	COG0825	malonyl-CoA metabolic process
SHJGH_RS18390	COG1404	Belongs to the peptidase S8 family
SHJGH_RS18415	COG1077	Cell shape determining protein MreB Mrl
SHJGH_RS18435	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJGH_RS18435	COG0515	serine threonine protein kinase
SHJGH_RS18440	COG0367	asparagine synthase
SHJGH_RS18490	COG1487	ribonuclease activity
SHJGH_RS18515	COG1070	Carbohydrate kinase
SHJGH_RS18530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SHJGH_RS18540	COG0358	DNA primase activity
SHJGH_RS18550	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SHJGH_RS18560	COG2949	membrane
SHJGH_RS18565	COG0243	molybdopterin cofactor binding
SHJGH_RS18605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJGH_RS18610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SHJGH_RS18610	COG2146	nitrite reductase [NAD(P)H] activity
SHJGH_RS18620	COG2130	NADP-dependent
SHJGH_RS18625	COG1309	transcriptional regulator
SHJGH_RS18630	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS18635	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS18640	COG1175	transmembrane transport
SHJGH_RS18660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJGH_RS18660	COG0574	Belongs to the PEP-utilizing enzyme family
SHJGH_RS18665	COG1846	Transcriptional regulator
SHJGH_RS18665	COG1940	carbohydrate kinase activity
SHJGH_RS18670	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SHJGH_RS18700	COG0477	Major facilitator Superfamily
SHJGH_RS18710	COG0423	glycine-tRNA ligase activity
SHJGH_RS18725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SHJGH_RS18735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SHJGH_RS18740	COG1381	Involved in DNA repair and RecF pathway recombination
SHJGH_RS18785	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS18815	COG1309	transcriptional regulator
SHJGH_RS18825	COG0702	epimerase
SHJGH_RS18855	COG0747	negative chemotaxis
SHJGH_RS18865	COG0444	Belongs to the ABC transporter superfamily
SHJGH_RS18870	COG4608	Belongs to the ABC transporter superfamily
SHJGH_RS18875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJGH_RS18890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SHJGH_RS18920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SHJGH_RS18940	COG2315	Protein conserved in bacteria
SHJGH_RS18950	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SHJGH_RS18960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJGH_RS18965	COG4948	Mandelate Racemase Muconate Lactonizing
SHJGH_RS18975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJGH_RS18980	COG1234	tRNA 3'-trailer cleavage
SHJGH_RS18985	COG0537	adenosine 5'-monophosphoramidase activity
SHJGH_RS18990	COG0793	Belongs to the peptidase S41A family
SHJGH_RS18990	COG4946	Tricorn protease homolog
SHJGH_RS19010	COG2070	2-Nitropropane dioxygenase
SHJGH_RS19015	COG0484	heat shock protein binding
SHJGH_RS19020	COG1420	regulation of RNA biosynthetic process
SHJGH_RS19055	COG0481	GTPase activity
SHJGH_RS19060	COG0268	Binds directly to 16S ribosomal RNA
SHJGH_RS19075	COG2353	YceI-like domain
SHJGH_RS19090	COG1555	photosystem II stabilization
SHJGH_RS19090	COG1596	polysaccharide export
SHJGH_RS19100	COG1307	EDD domain protein, DegV family
SHJGH_RS19110	COG0495	leucyl-tRNA aminoacylation
SHJGH_RS19120	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHJGH_RS19145	COG0588	phosphoglycerate mutase activity
SHJGH_RS19160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SHJGH_RS19175	COG0501	Belongs to the peptidase M48B family
SHJGH_RS19190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SHJGH_RS19200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SHJGH_RS19215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJGH_RS19220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJGH_RS19230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SHJGH_RS19235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SHJGH_RS19240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SHJGH_RS19245	COG0371	Dehydrogenase
SHJGH_RS19255	COG1530	ribonuclease E activity
SHJGH_RS19280	COG0772	Belongs to the SEDS family
SHJGH_RS19285	COG0768	penicillin binding
SHJGH_RS19300	COG1077	Cell shape determining protein MreB Mrl
SHJGH_RS19305	COG0105	UTP biosynthetic process
SHJGH_RS19315	COG0285	dihydrofolate synthase activity
SHJGH_RS19320	COG0525	valine-tRNA ligase activity
SHJGH_RS19330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SHJGH_RS19335	COG0740	serine-type endopeptidase activity
SHJGH_RS19340	COG0740	serine-type endopeptidase activity
SHJGH_RS19345	COG0544	peptidyl-prolyl cis-trans isomerase activity
SHJGH_RS19365	COG3594	Acyltransferase
SHJGH_RS19380	COG4552	Acetyltransferase involved in intracellular survival and related
SHJGH_RS19395	COG1113	amino acid transport
SHJGH_RS19410	COG1113	amino acid transport
SHJGH_RS19415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SHJGH_RS19420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SHJGH_RS19435	COG2755	lipolytic protein G-D-S-L family
SHJGH_RS19465	COG0346	lactoylglutathione lyase activity
SHJGH_RS19520	COG0697	spore germination
SHJGH_RS19525	COG1846	Transcriptional regulator
SHJGH_RS19545	COG1595	DNA-templated transcription, initiation
SHJGH_RS19555	COG1131	(ABC) transporter
SHJGH_RS19575	COG0668	transmembrane transport
SHJGH_RS19595	COG1653	transport
SHJGH_RS19600	COG1175	transmembrane transport
SHJGH_RS19605	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS19610	COG1486	melibiose metabolic process
SHJGH_RS19620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SHJGH_RS19630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJGH_RS19665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SHJGH_RS19685	COG1136	(ABC) transporter
SHJGH_RS19730	COG0629	single-stranded DNA binding
SHJGH_RS19735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SHJGH_RS19755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SHJGH_RS19815	COG0297	glycogen (starch) synthase activity
SHJGH_RS19820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SHJGH_RS19840	COG0438	transferase activity, transferring glycosyl groups
SHJGH_RS19880	COG1022	Amp-dependent synthetase and ligase
SHJGH_RS19895	COG1131	(ABC) transporter
SHJGH_RS19915	COG3962	Belongs to the TPP enzyme family
SHJGH_RS19920	COG3718	enzyme involved in inositol metabolism
SHJGH_RS19930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJGH_RS19945	COG2409	Drug exporters of the RND superfamily
SHJGH_RS19985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SHJGH_RS20015	COG1129	ABC transporter
SHJGH_RS20025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJGH_RS20030	COG1869	D-ribose catabolic process
SHJGH_RS20045	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS20050	COG1609	Transcriptional regulator
SHJGH_RS20060	COG1846	Transcriptional regulator
SHJGH_RS20060	COG0456	acetyltransferase
SHJGH_RS20080	COG1472	Belongs to the glycosyl hydrolase 3 family
SHJGH_RS20115	COG0028	Belongs to the TPP enzyme family
SHJGH_RS20125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJGH_RS20145	COG1946	Acyl-CoA thioesterase
SHJGH_RS20155	COG1309	transcriptional regulator
SHJGH_RS20160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SHJGH_RS20175	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS20195	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SHJGH_RS20230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SHJGH_RS20235	COG0589	response to stress
SHJGH_RS20245	COG4977	sequence-specific DNA binding
SHJGH_RS20250	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SHJGH_RS20270	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS20295	COG3979	chitinase
SHJGH_RS20305	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS20330	COG0406	alpha-ribazole phosphatase activity
SHJGH_RS20355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS20385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SHJGH_RS20390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJGH_RS20395	COG0765	amino acid transport
SHJGH_RS20400	COG0765	amino acid transport
SHJGH_RS20405	COG1126	abc transporter atp-binding protein
SHJGH_RS20425	COG3397	chitin binding
SHJGH_RS20445	COG2186	Transcriptional regulator
SHJGH_RS20470	COG1940	carbohydrate kinase activity
SHJGH_RS20475	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS20480	COG4702	Belongs to the UPF0303 family
SHJGH_RS20495	COG0706	membrane insertase activity
SHJGH_RS20515	COG3764	Sortase (surface protein transpeptidase)
SHJGH_RS20585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJGH_RS20615	COG2271	Major facilitator Superfamily
SHJGH_RS20620	COG2733	membrane
SHJGH_RS20630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SHJGH_RS20670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJGH_RS20685	COG4555	ABC transporter
SHJGH_RS20700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SHJGH_RS20705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SHJGH_RS20710	COG1263	PTS System
SHJGH_RS20715	COG1263	PTS System
SHJGH_RS20750	COG1113	amino acid transport
SHJGH_RS20760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SHJGH_RS20770	COG1335	isochorismatase
SHJGH_RS20810	COG0277	FAD linked oxidase domain protein
SHJGH_RS20820	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SHJGH_RS20875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SHJGH_RS20890	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SHJGH_RS20900	COG1678	Uncharacterized ACR, COG1678
SHJGH_RS20905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SHJGH_RS20910	COG0776	regulation of translation
SHJGH_RS20920	COG3973	AAA domain
SHJGH_RS20940	COG2223	nitrite transmembrane transporter activity
SHJGH_RS20965	COG0583	DNA-binding transcription factor activity
SHJGH_RS20975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SHJGH_RS20980	COG0793	Belongs to the peptidase S41A family
SHJGH_RS20985	COG2177	Part of the ABC transporter FtsEX involved in
SHJGH_RS20990	COG2884	Cell division ATP-binding protein ftsE
SHJGH_RS21005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SHJGH_RS21010	COG0515	serine threonine protein kinase
SHJGH_RS21015	COG0515	serine threonine protein kinase
SHJGH_RS21020	COG1674	ftsk spoiiie
SHJGH_RS21030	COG1175	transmembrane transport
SHJGH_RS21035	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS21040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJGH_RS21045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJGH_RS21050	COG0463	Glycosyl transferase, family 2
SHJGH_RS21050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJGH_RS21055	COG1764	response to oxidative stress
SHJGH_RS21060	COG1846	Transcriptional regulator
SHJGH_RS21075	COG1215	transferase activity, transferring glycosyl groups
SHJGH_RS21090	COG1134	teichoic acid transport
SHJGH_RS21095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SHJGH_RS21100	COG1215	transferase activity, transferring glycosyl groups
SHJGH_RS21110	COG2902	Dehydrogenase
SHJGH_RS21135	COG0653	protein targeting
SHJGH_RS21145	COG3214	Protein conserved in bacteria
SHJGH_RS21155	COG2197	response regulator
SHJGH_RS21160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SHJGH_RS21170	COG0823	Involved in the tonB-independent uptake of proteins
SHJGH_RS21175	COG5000	phosphorelay sensor kinase activity
SHJGH_RS21175	COG5002	protein histidine kinase activity
SHJGH_RS21180	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS21205	COG0714	Associated with various cellular activities
SHJGH_RS21245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SHJGH_RS21250	COG0681	Belongs to the peptidase S26 family
SHJGH_RS21260	COG1482	cell wall glycoprotein biosynthetic process
SHJGH_RS21310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SHJGH_RS21315	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SHJGH_RS21315	COG0778	Nitroreductase
SHJGH_RS21345	COG1316	TRANSCRIPTIONal
SHJGH_RS21350	COG1316	TRANSCRIPTIONal
SHJGH_RS21360	COG1316	TRANSCRIPTIONal
SHJGH_RS21370	COG1316	TRANSCRIPTIONal
SHJGH_RS21385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SHJGH_RS21410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SHJGH_RS21425	COG2205	protein histidine kinase activity
SHJGH_RS21430	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS21435	COG3104	oligopeptide transport
SHJGH_RS21450	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJGH_RS21455	COG1191	sigma factor activity
SHJGH_RS21465	COG1228	amidohydrolase
SHJGH_RS21475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJGH_RS21480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SHJGH_RS21520	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SHJGH_RS21530	COG4221	oxidoreductase activity
SHJGH_RS21545	COG2755	lipolytic protein G-D-S-L family
SHJGH_RS21550	COG0183	Belongs to the thiolase family
SHJGH_RS21585	COG0577	efflux transmembrane transporter activity
SHJGH_RS21585	COG1136	(ABC) transporter
SHJGH_RS21590	COG0577	efflux transmembrane transporter activity
SHJGH_RS21595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SHJGH_RS21600	COG1252	NADH dehydrogenase
SHJGH_RS21620	COG0148	phosphopyruvate hydratase activity
SHJGH_RS21640	COG2124	cytochrome p450
SHJGH_RS21700	COG0789	Transcriptional regulator
SHJGH_RS21710	COG0577	efflux transmembrane transporter activity
SHJGH_RS21715	COG1136	(ABC) transporter
SHJGH_RS21720	COG0477	Major facilitator Superfamily
SHJGH_RS21750	COG4585	Histidine kinase
SHJGH_RS21765	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SHJGH_RS21770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SHJGH_RS21775	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SHJGH_RS21780	COG0193	aminoacyl-tRNA hydrolase activity
SHJGH_RS21790	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SHJGH_RS21800	COG1309	transcriptional regulator
SHJGH_RS21810	COG4106	trans-aconitate 2-methyltransferase activity
SHJGH_RS21820	COG2197	response regulator
SHJGH_RS21840	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SHJGH_RS21880	COG0488	(ABC) transporter
SHJGH_RS21890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SHJGH_RS21895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SHJGH_RS21900	COG3583	domain protein
SHJGH_RS21900	COG3584	3D domain protein
SHJGH_RS21905	COG0084	hydrolase, TatD family'
SHJGH_RS21945	COG0310	cobalt ion transport
SHJGH_RS21955	COG1122	ATPase activity
SHJGH_RS21975	COG0442	prolyl-tRNA aminoacylation
SHJGH_RS21980	COG2409	Drug exporters of the RND superfamily
SHJGH_RS21990	COG0793	Belongs to the peptidase S41A family
SHJGH_RS21990	COG4946	Tricorn protease homolog
SHJGH_RS22000	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS22005	COG2267	carboxylic ester hydrolase activity
SHJGH_RS22010	COG2072	flavoprotein involved in K transport
SHJGH_RS22040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SHJGH_RS22045	COG0315	cyclic pyranopterin monophosphate synthase activity
SHJGH_RS22045	COG0521	Mo-molybdopterin cofactor biosynthetic process
SHJGH_RS22050	COG0315	cyclic pyranopterin monophosphate synthase activity
SHJGH_RS22060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SHJGH_RS22065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SHJGH_RS22080	COG3263	regulation of cellular component size
SHJGH_RS22095	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SHJGH_RS22115	COG3191	aminopeptidase activity
SHJGH_RS22120	COG1376	ErfK ybiS ycfS ynhG family protein
SHJGH_RS22135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SHJGH_RS22135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SHJGH_RS22135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SHJGH_RS22140	COG1105	Belongs to the carbohydrate kinase PfkB family
SHJGH_RS22145	COG1349	DNA-binding transcription factor activity
SHJGH_RS22150	COG0477	Major facilitator Superfamily
SHJGH_RS22170	COG1247	-acetyltransferase
SHJGH_RS22175	COG3384	dioxygenase
SHJGH_RS22180	COG1846	Transcriptional regulator
SHJGH_RS22205	COG1414	Transcriptional regulator
SHJGH_RS22225	COG0582	viral genome integration into host DNA
SHJGH_RS22245	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS22290	COG0277	FAD linked oxidase domain protein
SHJGH_RS22305	COG0386	Belongs to the glutathione peroxidase family
SHJGH_RS22325	COG1686	Belongs to the peptidase S11 family
SHJGH_RS22365	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SHJGH_RS22385	COG3629	intracellular signal transduction
SHJGH_RS22385	COG3903	Transcriptional regulator
SHJGH_RS22435	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJGH_RS22435	COG0515	serine threonine protein kinase
SHJGH_RS22450	COG1522	sequence-specific DNA binding
SHJGH_RS22455	COG1280	lysine exporter protein (LysE YggA)
SHJGH_RS22465	COG0259	pyridoxamine-phosphate oxidase activity
SHJGH_RS22475	COG2072	flavoprotein involved in K transport
SHJGH_RS22510	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJGH_RS22555	COG2945	thiolester hydrolase activity
SHJGH_RS22555	COG0596	Alpha beta hydrolase
SHJGH_RS22565	COG4821	SIS domain
SHJGH_RS22580	COG0259	pyridoxamine-phosphate oxidase activity
SHJGH_RS22595	COG1309	transcriptional regulator
SHJGH_RS22605	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS22615	COG4770	biotin carboxylase activity
SHJGH_RS22620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SHJGH_RS22635	COG0281	malic enzyme
SHJGH_RS22640	COG5006	permease, DMT superfamily
SHJGH_RS22645	COG1132	(ABC) transporter
SHJGH_RS22660	COG0247	lactate metabolic process
SHJGH_RS22660	COG0277	FAD linked oxidase domain protein
SHJGH_RS22665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SHJGH_RS22680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJGH_RS22685	COG0667	Aldo Keto reductase
SHJGH_RS22715	COG2252	PERMEase
SHJGH_RS22725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SHJGH_RS22755	COG2326	polyphosphate kinase activity
SHJGH_RS22780	COG2814	Major facilitator Superfamily
SHJGH_RS22790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SHJGH_RS22795	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SHJGH_RS22800	COG1278	Cold shock
SHJGH_RS22830	COG1061	Type III restriction enzyme res subunit
SHJGH_RS22835	COG1231	oxidoreductase activity
SHJGH_RS22855	COG3973	AAA domain
SHJGH_RS22875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SHJGH_RS22890	COG1737	Transcriptional regulator
SHJGH_RS22895	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SHJGH_RS22910	COG0459	protein refolding
SHJGH_RS22915	COG1278	Cold shock
SHJGH_RS22930	COG0463	Glycosyl transferase, family 2
SHJGH_RS22980	COG5001	Diguanylate cyclase
SHJGH_RS22980	COG3300	MHYT domain
SHJGH_RS23000	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SHJGH_RS23060	COG3842	ATPase activity
SHJGH_RS23085	COG0215	cysteine-tRNA ligase activity
SHJGH_RS23095	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SHJGH_RS23100	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SHJGH_RS23105	COG1329	Transcriptional regulator
SHJGH_RS23120	COG5002	protein histidine kinase activity
SHJGH_RS23150	COG0588	phosphoglycerate mutase activity
SHJGH_RS23240	COG0438	transferase activity, transferring glycosyl groups
SHJGH_RS23275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SHJGH_RS23290	COG1309	transcriptional regulator
SHJGH_RS23305	COG2186	Transcriptional regulator
SHJGH_RS23315	COG2188	Transcriptional regulator
SHJGH_RS23325	COG1490	D-aminoacyl-tRNA deacylase activity
SHJGH_RS23345	COG2897	thiosulfate sulfurtransferase activity
SHJGH_RS23370	COG3485	protocatechuate 3,4-dioxygenase
SHJGH_RS23380	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SHJGH_RS23395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SHJGH_RS23400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SHJGH_RS23420	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS23425	COG1609	Transcriptional regulator
SHJGH_RS23430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SHJGH_RS23440	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS23450	COG1846	Transcriptional regulator
SHJGH_RS23460	COG0737	Belongs to the 5'-nucleotidase family
SHJGH_RS23465	COG0456	acetyltransferase
SHJGH_RS23475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SHJGH_RS23485	COG0406	alpha-ribazole phosphatase activity
SHJGH_RS23485	COG0494	nUDIX hydrolase
SHJGH_RS23500	COG1937	Protein conserved in bacteria
SHJGH_RS23510	COG0306	phosphate transporter
SHJGH_RS23515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SHJGH_RS23530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SHJGH_RS23535	COG0277	FAD linked oxidase domain protein
SHJGH_RS23540	COG0671	phosphoesterase, PA-phosphatase related
SHJGH_RS23635	COG1252	NADH dehydrogenase
SHJGH_RS23665	COG0579	oxidoreductase
SHJGH_RS23670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SHJGH_RS23680	COG0667	Aldo Keto reductase
SHJGH_RS23700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SHJGH_RS23700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SHJGH_RS23710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SHJGH_RS23715	COG0477	Major facilitator Superfamily
SHJGH_RS23745	COG0513	Belongs to the DEAD box helicase family
SHJGH_RS23780	COG0582	viral genome integration into host DNA
SHJGH_RS23845	COG0494	nUDIX hydrolase
SHJGH_RS23860	COG2188	Transcriptional regulator
SHJGH_RS23865	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SHJGH_RS23880	COG1643	Atp-dependent helicase
SHJGH_RS23915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SHJGH_RS23945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SHJGH_RS23950	COG0047	phosphoribosylformylglycinamidine synthase activity
SHJGH_RS23955	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SHJGH_RS23985	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SHJGH_RS24000	COG0151	Belongs to the GarS family
SHJGH_RS24030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SHJGH_RS24035	COG0798	PFAM Bile acid sodium symporter
SHJGH_RS24040	COG0640	Transcriptional regulator
SHJGH_RS24055	COG1276	copper resistance
SHJGH_RS24055	COG2372	response to copper ion
SHJGH_RS24070	COG2375	cellular response to nickel ion
SHJGH_RS24070	COG1132	(ABC) transporter
SHJGH_RS24090	COG0433	COG0433 Predicted ATPase
SHJGH_RS24105	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SHJGH_RS24140	COG1191	sigma factor activity
SHJGH_RS24145	COG1191	sigma factor activity
SHJGH_RS24155	COG0477	Major facilitator Superfamily
SHJGH_RS24160	COG2353	YceI-like domain
SHJGH_RS24165	COG3467	pyridoxamine 5'-phosphate
SHJGH_RS24175	COG0477	Major facilitator Superfamily
SHJGH_RS24180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SHJGH_RS24190	COG2205	protein histidine kinase activity
SHJGH_RS24195	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS24215	COG1846	Transcriptional regulator
SHJGH_RS24250	COG2801	Transposase and inactivated derivatives
SHJGH_RS24280	COG2188	Transcriptional regulator
SHJGH_RS24350	COG0784	Response regulator, receiver
SHJGH_RS24355	COG1309	transcriptional regulator
SHJGH_RS24360	COG2814	Major facilitator Superfamily
SHJGH_RS24365	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS24370	COG1595	DNA-templated transcription, initiation
SHJGH_RS24380	COG3415	Transposase
SHJGH_RS24380	COG2801	Transposase and inactivated derivatives
SHJGH_RS24390	COG0251	oxidation-reduction process
SHJGH_RS24400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SHJGH_RS24415	COG0653	protein targeting
SHJGH_RS24435	COG0006	proline dipeptidase activity
SHJGH_RS24440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SHJGH_RS24475	COG2837	iron assimilation
SHJGH_RS24485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SHJGH_RS24490	COG0561	phosphatase activity
SHJGH_RS24530	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SHJGH_RS24540	COG0561	phosphatase activity
SHJGH_RS24545	COG4988	ABC transporter
SHJGH_RS24550	COG1294	oxidase, subunit
SHJGH_RS24555	COG1271	oxidase subunit
SHJGH_RS24560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SHJGH_RS24565	COG1609	Transcriptional regulator
SHJGH_RS24585	COG2801	Transposase and inactivated derivatives
SHJGH_RS24590	COG2963	transposase activity
SHJGH_RS24600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SHJGH_RS24625	COG0662	Cupin 2, conserved barrel domain protein
SHJGH_RS24630	COG1950	PFAM Membrane protein of
SHJGH_RS24635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SHJGH_RS24640	COG0626	cystathionine gamma-synthase activity
SHJGH_RS24675	COG2814	Major facilitator Superfamily
SHJGH_RS24695	COG0305	Participates in initiation and elongation during chromosome replication
SHJGH_RS24705	COG0359	binds to the 23S rRNA
SHJGH_RS24710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SHJGH_RS24715	COG0629	single-stranded DNA binding
SHJGH_RS24720	COG0360	Binds together with S18 to 16S ribosomal RNA
SHJGH_RS24745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJGH_RS24765	COG0617	tRNA 3'-terminal CCA addition
SHJGH_RS24780	COG2815	serine threonine protein kinase
SHJGH_RS24780	COG0515	serine threonine protein kinase
SHJGH_RS24785	COG1595	DNA-templated transcription, initiation
SHJGH_RS24795	COG0492	ferredoxin-NADP+ reductase activity
SHJGH_RS24800	COG3118	belongs to the thioredoxin family
SHJGH_RS24815	COG1192	Involved in chromosome partitioning
SHJGH_RS24820	COG0357	Ribosomal RNA small subunit methyltransferase G
SHJGH_RS24830	COG0706	membrane insertase activity
SHJGH_RS24835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SHJGH_RS24850	COG0592	DNA-directed DNA polymerase activity
SHJGH_RS24855	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SHJGH_RS24860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SHJGH_RS24865	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SHJGH_RS24870	COG0187	DNA topoisomerase II activity
SHJGH_RS24875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SHJGH_RS24890	COG4249	Peptidase C14 caspase catalytic subunit p20
SHJGH_RS24890	COG2319	Wd-40 repeat
SHJGH_RS24890	COG4249	Peptidase C14 caspase catalytic subunit p20
SHJGH_RS24890	COG2319	Wd-40 repeat
SHJGH_RS24920	COG0515	serine threonine protein kinase
SHJGH_RS24945	COG0705	Rhomboid family
SHJGH_RS24970	COG3764	Sortase (surface protein transpeptidase)
SHJGH_RS24975	COG3764	Sortase (surface protein transpeptidase)
SHJGH_RS24980	COG0515	serine threonine protein kinase
SHJGH_RS24985	COG0768	penicillin binding
SHJGH_RS25000	COG1716	ATPase activity
SHJGH_RS25005	COG1716	ATPase activity
SHJGH_RS25045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SHJGH_RS25050	COG2151	metal-sulfur cluster biosynthetic enzyme
SHJGH_RS25055	COG3396	Phenylacetate-CoA oxygenase
SHJGH_RS25060	COG3460	Phenylacetate-CoA oxygenase
SHJGH_RS25065	COG3396	Phenylacetate-CoA oxygenase
SHJGH_RS25090	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJGH_RS25095	COG1309	transcriptional regulator
SHJGH_RS25100	COG1522	sequence-specific DNA binding
SHJGH_RS25130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SHJGH_RS25135	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS25135	COG0604	alcohol dehydrogenase
SHJGH_RS25135	COG3321	synthase
SHJGH_RS25150	COG0515	serine threonine protein kinase
SHJGH_RS25155	COG0515	serine threonine protein kinase
SHJGH_RS25170	COG0022	dehydrogenase e1 component
SHJGH_RS25175	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJGH_RS25240	COG1362	aminopeptidase activity
SHJGH_RS25245	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS25260	COG1741	Belongs to the pirin family
SHJGH_RS25275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SHJGH_RS25285	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SHJGH_RS25295	COG1289	transmembrane transporter activity
SHJGH_RS25355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SHJGH_RS25360	COG1957	nucleoside hydrolase
SHJGH_RS25365	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SHJGH_RS25370	COG0640	Transcriptional regulator
SHJGH_RS25375	COG0366	Alpha amylase catalytic
SHJGH_RS25425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJGH_RS25430	COG1595	DNA-templated transcription, initiation
SHJGH_RS25445	COG0513	Belongs to the DEAD box helicase family
SHJGH_RS25450	COG1278	Cold shock
SHJGH_RS25460	COG2197	response regulator
SHJGH_RS25465	COG4585	Histidine kinase
SHJGH_RS25480	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS25495	COG0477	Major facilitator Superfamily
SHJGH_RS25505	COG1959	2 iron, 2 sulfur cluster binding
SHJGH_RS25510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SHJGH_RS25515	COG0531	amino acid
SHJGH_RS25520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SHJGH_RS25525	COG1191	sigma factor activity
SHJGH_RS25595	COG2815	serine threonine protein kinase
SHJGH_RS25595	COG0515	serine threonine protein kinase
SHJGH_RS25625	COG0142	geranyltranstransferase activity
SHJGH_RS25650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJGH_RS25665	COG0717	Belongs to the dCTP deaminase family
SHJGH_RS25670	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SHJGH_RS25700	COG2181	nitrate reductase activity
SHJGH_RS25700	COG0247	lactate metabolic process
SHJGH_RS25705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SHJGH_RS25710	COG0443	Heat shock 70 kDa protein
SHJGH_RS25715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHJGH_RS25720	COG0484	heat shock protein binding
SHJGH_RS25725	COG0789	Transcriptional regulator
SHJGH_RS25730	COG4213	ABC transporter substrate-binding protein
SHJGH_RS25760	COG0542	response to heat
SHJGH_RS25785	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SHJGH_RS25800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SHJGH_RS25810	COG0477	Major facilitator Superfamily
SHJGH_RS25825	COG3483	tryptophan 2,3-dioxygenase activity
SHJGH_RS25830	COG3844	kynureninase activity
SHJGH_RS25840	COG4585	Histidine kinase
SHJGH_RS25845	COG2197	response regulator
SHJGH_RS25865	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SHJGH_RS25875	COG1802	Transcriptional regulator
SHJGH_RS25880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SHJGH_RS25900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SHJGH_RS25905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SHJGH_RS25935	COG1595	DNA-templated transcription, initiation
SHJGH_RS25965	COG0701	Predicted permease
SHJGH_RS26025	COG1408	metallophosphoesterase
SHJGH_RS26035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJGH_RS26045	COG0003	Pfam Anion-transporting ATPase
SHJGH_RS26065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJGH_RS26095	COG2267	carboxylic ester hydrolase activity
SHJGH_RS26110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJGH_RS26115	COG0659	secondary active sulfate transmembrane transporter activity
SHJGH_RS26175	COG1205	dead DEAH box helicase
SHJGH_RS26175	COG1111	helicase
SHJGH_RS26180	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJGH_RS26190	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SHJGH_RS26210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SHJGH_RS26210	COG1754	DNA topoisomerase type I activity
SHJGH_RS26215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SHJGH_RS26420	COG3629	intracellular signal transduction
SHJGH_RS26420	COG3903	Transcriptional regulator
SHJGH_RS26425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SHJGH_RS26425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SHJGH_RS26455	COG0640	Transcriptional regulator
SHJGH_RS26480	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS26485	COG2318	DinB family
SHJGH_RS26495	COG0076	glutamate decarboxylase activity
SHJGH_RS26505	COG0789	Transcriptional regulator
SHJGH_RS26520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SHJGH_RS26525	COG2027	D-alanyl-D-alanine carboxypeptidase
SHJGH_RS26535	COG0037	tRNA processing
SHJGH_RS26550	COG0302	gtp cyclohydrolase
SHJGH_RS26565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SHJGH_RS26580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SHJGH_RS26580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SHJGH_RS26605	COG0649	NAD binding
SHJGH_RS26620	COG2197	response regulator
SHJGH_RS26645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SHJGH_RS26650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SHJGH_RS26660	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SHJGH_RS26680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SHJGH_RS26705	COG0739	heme binding
SHJGH_RS26725	COG2205	protein histidine kinase activity
SHJGH_RS26730	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS26740	COG1595	DNA-templated transcription, initiation
SHJGH_RS26755	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SHJGH_RS26780	COG0248	Ppx GppA phosphatase
SHJGH_RS26785	COG1082	Xylose isomerase domain protein TIM barrel
SHJGH_RS26790	COG1309	transcriptional regulator
SHJGH_RS26795	COG0129	dihydroxy-acid dehydratase activity
SHJGH_RS26805	COG4991	sh3 domain protein
SHJGH_RS26820	COG1129	ABC transporter
SHJGH_RS26820	COG0842	Transport permease protein
SHJGH_RS26830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SHJGH_RS26835	COG0180	Tryptophanyl-tRNA synthetase
SHJGH_RS26855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SHJGH_RS26865	COG2223	nitrite transmembrane transporter activity
SHJGH_RS26870	COG0123	including yeast histone deacetylase and acetoin utilization protein
SHJGH_RS26915	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SHJGH_RS26920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SHJGH_RS26925	COG0181	hydroxymethylbilane synthase activity
SHJGH_RS26930	COG1648	precorrin-2 dehydrogenase activity
SHJGH_RS26930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SHJGH_RS26935	COG0113	porphobilinogen synthase activity
SHJGH_RS26975	COG3629	intracellular signal transduction
SHJGH_RS26975	COG3903	Transcriptional regulator
SHJGH_RS26980	COG0018	arginyl-trna synthetase
SHJGH_RS26985	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SHJGH_RS27005	COG1690	Belongs to the RtcB family
SHJGH_RS27025	COG0702	epimerase
SHJGH_RS27040	COG1742	UPF0060 membrane protein
SHJGH_RS27045	COG1733	regulation of RNA biosynthetic process
SHJGH_RS27055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS27060	COG0431	NADPH-dependent FMN reductase
SHJGH_RS27070	COG2205	protein histidine kinase activity
SHJGH_RS27080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SHJGH_RS27080	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SHJGH_RS27090	COG2362	D-Aminopeptidase
SHJGH_RS27120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SHJGH_RS27150	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SHJGH_RS27180	COG2226	methyltransferase
SHJGH_RS27195	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SHJGH_RS27200	COG0406	alpha-ribazole phosphatase activity
SHJGH_RS27215	COG0785	Cytochrome C biogenesis protein
SHJGH_RS27220	COG1333	cytochrome c biogenesis protein
SHJGH_RS27225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SHJGH_RS27245	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SHJGH_RS27250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SHJGH_RS27255	COG0163	prenyltransferase activity
SHJGH_RS27265	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SHJGH_RS27270	COG1573	uracil-dna glycosylase
SHJGH_RS27285	COG1309	transcriptional regulator
SHJGH_RS27300	COG0583	DNA-binding transcription factor activity
SHJGH_RS27320	COG2226	methyltransferase
SHJGH_RS27325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJGH_RS27325	COG0515	serine threonine protein kinase
SHJGH_RS27345	COG1278	Cold shock
SHJGH_RS27350	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SHJGH_RS27360	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SHJGH_RS27370	COG3979	chitinase
SHJGH_RS27390	COG2226	methyltransferase
SHJGH_RS27410	COG0242	peptide deformylase activity
SHJGH_RS27425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS27430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS27435	COG0649	NAD binding
SHJGH_RS27445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHJGH_RS27450	COG1034	ATP synthesis coupled electron transport
SHJGH_RS27455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SHJGH_RS27460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS27465	COG0839	Belongs to the complex I subunit 6 family
SHJGH_RS27470	COG0713	ATP synthesis coupled electron transport
SHJGH_RS27475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SHJGH_RS27485	COG1007	ATP synthesis coupled electron transport
SHJGH_RS27490	COG0514	ATP-dependent DNA helicase (RecQ)
SHJGH_RS27505	COG0561	phosphatase activity
SHJGH_RS27510	COG5280	Phage tail tape measure protein TP901
SHJGH_RS27510	COG3953	SLT domain
SHJGH_RS27515	COG0142	geranyltranstransferase activity
SHJGH_RS27525	COG1131	(ABC) transporter
SHJGH_RS27560	COG0702	epimerase
SHJGH_RS27565	COG1733	regulation of RNA biosynthetic process
SHJGH_RS27570	COG1013	pyruvate-flavodoxin oxidoreductase activity
SHJGH_RS27575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SHJGH_RS27575	COG0674	pyruvate-flavodoxin oxidoreductase activity
SHJGH_RS27595	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS27600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS27605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS27610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SHJGH_RS27615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS27620	COG0839	Belongs to the complex I subunit 6 family
SHJGH_RS27625	COG0713	ATP synthesis coupled electron transport
SHJGH_RS27635	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS27640	COG1007	ATP synthesis coupled electron transport
SHJGH_RS27645	COG0501	Belongs to the peptidase M48B family
SHJGH_RS27655	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJGH_RS27655	COG1672	PFAM Archaeal ATPase
SHJGH_RS27680	COG2261	transglycosylase associated protein
SHJGH_RS27685	COG1666	GTP binding
SHJGH_RS27710	COG0702	epimerase
SHJGH_RS27730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SHJGH_RS27735	COG2030	dehydratase
SHJGH_RS27750	COG0477	Major facilitator Superfamily
SHJGH_RS27760	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SHJGH_RS27775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJGH_RS27780	COG0436	Aminotransferase
SHJGH_RS27795	COG0250	Participates in transcription elongation, termination and antitermination
SHJGH_RS27805	COG0081	regulation of translation
SHJGH_RS27825	COG0085	RNA polymerase activity
SHJGH_RS27830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SHJGH_RS27865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SHJGH_RS27870	COG0049	tRNA binding
SHJGH_RS27875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SHJGH_RS27895	COG0051	transcription antitermination factor activity, RNA binding
SHJGH_RS27900	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SHJGH_RS27905	COG0088	Forms part of the polypeptide exit tunnel
SHJGH_RS27910	COG0089	rRNA binding
SHJGH_RS27915	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SHJGH_RS27920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SHJGH_RS27925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SHJGH_RS27930	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SHJGH_RS27935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SHJGH_RS27940	COG0255	Belongs to the universal ribosomal protein uL29 family
SHJGH_RS27945	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SHJGH_RS27950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SHJGH_RS27955	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SHJGH_RS27960	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SHJGH_RS27965	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SHJGH_RS27970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SHJGH_RS27975	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SHJGH_RS27980	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SHJGH_RS27985	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SHJGH_RS27990	COG1841	ribosomal large subunit assembly
SHJGH_RS27995	COG0200	Binds to the 23S rRNA
SHJGH_RS28005	COG0563	adenylate kinase activity
SHJGH_RS28015	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SHJGH_RS28020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SHJGH_RS28025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SHJGH_RS28030	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SHJGH_RS28035	COG0202	RNA polymerase activity
SHJGH_RS28040	COG0203	ribosomal protein L17
SHJGH_RS28045	COG0101	tRNA pseudouridine synthase activity
SHJGH_RS28065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SHJGH_RS28080	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SHJGH_RS28085	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SHJGH_RS28090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SHJGH_RS28100	COG1072	(Pantothenic acid kinase))
SHJGH_RS28105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SHJGH_RS28110	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS28115	COG0736	holo-[acyl-carrier-protein] synthase activity
SHJGH_RS28125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SHJGH_RS28135	COG0802	atpase or kinase
SHJGH_RS28160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SHJGH_RS28175	COG1609	Transcriptional regulator
SHJGH_RS28190	COG4941	Belongs to the sigma-70 factor family
SHJGH_RS28200	COG0726	polysaccharide deacetylase
SHJGH_RS28205	COG0726	polysaccharide deacetylase
SHJGH_RS28215	COG0459	protein refolding
SHJGH_RS28225	COG4221	oxidoreductase activity
SHJGH_RS28235	COG0583	DNA-binding transcription factor activity
SHJGH_RS28250	COG1595	DNA-templated transcription, initiation
SHJGH_RS28260	COG0516	GMP reductase activity
SHJGH_RS28270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SHJGH_RS28280	COG0515	serine threonine protein kinase
SHJGH_RS28280	COG2815	serine threonine protein kinase
SHJGH_RS28285	COG0515	serine threonine protein kinase
SHJGH_RS28290	COG0515	serine threonine protein kinase
SHJGH_RS28290	COG2815	serine threonine protein kinase
SHJGH_RS28305	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS28320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SHJGH_RS28320	COG0519	Catalyzes the synthesis of GMP from XMP
SHJGH_RS28375	COG2197	response regulator
SHJGH_RS28380	COG0791	NLP P60 protein
SHJGH_RS28390	COG0791	NLP P60 protein
SHJGH_RS28400	COG0739	heme binding
SHJGH_RS28410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJGH_RS28410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJGH_RS28425	COG0714	Associated with various cellular activities
SHJGH_RS28430	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SHJGH_RS28440	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SHJGH_RS28445	COG0045	succinate-CoA ligase (ADP-forming) activity
SHJGH_RS28475	COG0138	bifunctional purine biosynthesis protein purh
SHJGH_RS28480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJGH_RS28495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SHJGH_RS28520	COG2409	Drug exporters of the RND superfamily
SHJGH_RS28530	COG3903	Transcriptional regulator
SHJGH_RS28530	COG3629	intracellular signal transduction
SHJGH_RS28535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS28540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJGH_RS28550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS28575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SHJGH_RS28620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SHJGH_RS28630	COG4585	Histidine kinase
SHJGH_RS28635	COG2197	response regulator
SHJGH_RS28645	COG0039	L-malate dehydrogenase activity
SHJGH_RS28660	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS28670	COG4175	Glycine betaine
SHJGH_RS28670	COG0517	IMP dehydrogenase activity
SHJGH_RS28675	COG4176	ABC-type proline glycine betaine transport system permease component
SHJGH_RS28690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJGH_RS28695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SHJGH_RS28710	COG0754	glutathionylspermidine amidase activity
SHJGH_RS28725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SHJGH_RS28730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SHJGH_RS28735	COG0180	Tryptophanyl-tRNA synthetase
SHJGH_RS28750	COG1295	ribonuclease BN
SHJGH_RS28765	COG1408	metallophosphoesterase
SHJGH_RS28780	COG1309	transcriptional regulator
SHJGH_RS28795	COG1053	succinate dehydrogenase
SHJGH_RS28805	COG2009	succinate dehydrogenase
SHJGH_RS28815	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SHJGH_RS28845	COG1595	DNA-templated transcription, initiation
SHJGH_RS28860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJGH_RS28860	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJGH_RS28880	COG1216	Glycosyl transferase, family 2
SHJGH_RS28895	COG2089	acid synthase
SHJGH_RS28915	COG1473	amidohydrolase
SHJGH_RS28915	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SHJGH_RS28920	COG1744	ABC transporter substrate-binding protein PnrA-like
SHJGH_RS28925	COG3845	ABC transporter
SHJGH_RS28930	COG4603	Belongs to the binding-protein-dependent transport system permease family
SHJGH_RS28935	COG1079	Belongs to the binding-protein-dependent transport system permease family
SHJGH_RS28960	COG2814	Major facilitator Superfamily
SHJGH_RS28965	COG0583	DNA-binding transcription factor activity
SHJGH_RS28975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJGH_RS29000	COG2205	protein histidine kinase activity
SHJGH_RS29005	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS29010	COG1595	DNA-templated transcription, initiation
SHJGH_RS29025	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS29030	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS29050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SHJGH_RS29075	COG4770	biotin carboxylase activity
SHJGH_RS29085	COG0424	maF-like protein
SHJGH_RS29095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SHJGH_RS29105	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJGH_RS29115	COG1024	Enoyl-CoA hydratase
SHJGH_RS29125	COG2986	histidine ammonia-lyase
SHJGH_RS29155	COG1136	(ABC) transporter
SHJGH_RS29160	COG1404	Belongs to the peptidase S8 family
SHJGH_RS29170	COG1064	alcohol dehydrogenase
SHJGH_RS29180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SHJGH_RS29190	COG0501	Belongs to the peptidase M48B family
SHJGH_RS29210	COG1595	DNA-templated transcription, initiation
SHJGH_RS29215	COG2255	four-way junction helicase activity
SHJGH_RS29220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SHJGH_RS29235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SHJGH_RS29245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJGH_RS29260	COG1331	Highly conserved protein containing a thioredoxin domain
SHJGH_RS29270	COG1309	transcriptional regulator
SHJGH_RS29280	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SHJGH_RS29315	COG0436	Aminotransferase
SHJGH_RS29335	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SHJGH_RS29350	COG1414	Transcriptional regulator
SHJGH_RS29360	COG2610	gluconate transmembrane transporter activity
SHJGH_RS29385	COG3209	COG3209 Rhs family protein
SHJGH_RS29415	COG2894	cell division
SHJGH_RS29445	COG3920	Histidine kinase
SHJGH_RS29450	COG2197	response regulator
SHJGH_RS29490	COG2226	methyltransferase
SHJGH_RS29495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SHJGH_RS29500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SHJGH_RS29505	COG0741	lytic transglycosylase activity
SHJGH_RS29515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJGH_RS29520	COG0450	alkyl hydroperoxide reductase
SHJGH_RS29535	COG1136	(ABC) transporter
SHJGH_RS29555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SHJGH_RS29570	COG0114	fumarate hydratase activity
SHJGH_RS29575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SHJGH_RS29575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SHJGH_RS29600	COG0778	Nitroreductase
SHJGH_RS29605	COG1722	exodeoxyribonuclease VII activity
SHJGH_RS29610	COG1570	exodeoxyribonuclease VII activity
SHJGH_RS29620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SHJGH_RS29635	COG0012	GTP binding
SHJGH_RS29640	COG0582	viral genome integration into host DNA
SHJGH_RS29645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SHJGH_RS29655	COG1181	Belongs to the D-alanine--D-alanine ligase family
SHJGH_RS29660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SHJGH_RS29690	COG0778	Nitroreductase
SHJGH_RS29690	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SHJGH_RS29705	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SHJGH_RS29710	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SHJGH_RS29730	COG0592	DNA-directed DNA polymerase activity
SHJGH_RS29740	COG1834	amidinotransferase
SHJGH_RS29775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SHJGH_RS29775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SHJGH_RS29785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SHJGH_RS29800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SHJGH_RS29810	COG3903	Transcriptional regulator
SHJGH_RS29810	COG3629	intracellular signal transduction
SHJGH_RS29815	COG3903	Transcriptional regulator
SHJGH_RS29815	COG3629	intracellular signal transduction
SHJGH_RS29870	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SHJGH_RS29875	COG1053	succinate dehydrogenase
SHJGH_RS29895	COG1217	gtp-binding protein TYPA
SHJGH_RS29900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJGH_RS29905	COG4166	transmembrane transport
SHJGH_RS29910	COG0601	transmembrane transport
SHJGH_RS29915	COG0444	Belongs to the ABC transporter superfamily
SHJGH_RS29920	COG4608	Belongs to the ABC transporter superfamily
SHJGH_RS29930	COG4608	Belongs to the ABC transporter superfamily
SHJGH_RS29935	COG0444	Belongs to the ABC transporter superfamily
SHJGH_RS29940	COG0601	transmembrane transport
SHJGH_RS29945	COG4166	transmembrane transport
SHJGH_RS29950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJGH_RS29960	COG0601	transmembrane transport
SHJGH_RS29975	COG4608	Belongs to the ABC transporter superfamily
SHJGH_RS29990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJGH_RS30005	COG1131	(ABC) transporter
SHJGH_RS30015	COG4585	Histidine kinase
SHJGH_RS30020	COG2197	response regulator
SHJGH_RS30030	COG0456	acetyltransferase
SHJGH_RS30030	COG1214	PFAM Peptidase M22, glycoprotease
SHJGH_RS30055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJGH_RS30060	COG1611	Belongs to the LOG family
SHJGH_RS30065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SHJGH_RS30075	COG0519	Catalyzes the synthesis of GMP from XMP
SHJGH_RS30080	COG1024	Enoyl-CoA hydratase
SHJGH_RS30090	COG1595	DNA-templated transcription, initiation
SHJGH_RS30100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SHJGH_RS30105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SHJGH_RS30150	COG0598	Magnesium transport protein CorA
SHJGH_RS30160	COG2814	Major facilitator Superfamily
SHJGH_RS30175	COG2095	MarC family integral membrane protein
SHJGH_RS30180	COG1432	Conserved Protein
SHJGH_RS30235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJGH_RS30305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJGH_RS30310	COG2816	NAD+ diphosphatase activity
SHJGH_RS30335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SHJGH_RS30385	COG3480	Lon protease (S16) C-terminal proteolytic domain
SHJGH_RS30395	COG1615	UPF0182 protein
SHJGH_RS30420	COG0753	catalase activity
SHJGH_RS30430	COG0483	inositol monophosphate 1-phosphatase activity
SHJGH_RS30450	COG2076	Multidrug Resistance protein
SHJGH_RS30460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SHJGH_RS30470	COG2135	peptidase activity
SHJGH_RS30480	COG1595	DNA-templated transcription, initiation
SHJGH_RS30485	COG5662	AntiSigma factor
SHJGH_RS30490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SHJGH_RS30490	COG2199	diguanylate cyclase activity
SHJGH_RS30505	COG0242	peptide deformylase activity
SHJGH_RS30515	COG2124	cytochrome p450
SHJGH_RS30535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SHJGH_RS30565	COG2188	Transcriptional regulator
SHJGH_RS30570	COG0363	glucosamine-6-phosphate deaminase activity
SHJGH_RS30575	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS30595	COG1597	lipid kinase activity
SHJGH_RS30610	COG2172	sigma factor antagonist activity
SHJGH_RS30625	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SHJGH_RS30635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SHJGH_RS30640	COG0142	geranyltranstransferase activity
SHJGH_RS30685	COG4106	trans-aconitate 2-methyltransferase activity
SHJGH_RS30690	COG1126	abc transporter atp-binding protein
SHJGH_RS30705	COG0281	malic enzyme
SHJGH_RS30710	COG0604	alcohol dehydrogenase
SHJGH_RS30750	COG2255	four-way junction helicase activity
SHJGH_RS30775	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJGH_RS30775	COG0567	Dehydrogenase, E1 component
SHJGH_RS30780	COG2205	protein histidine kinase activity
SHJGH_RS30785	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS30800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SHJGH_RS30880	COG0768	penicillin binding
SHJGH_RS30885	COG0772	Belongs to the SEDS family
SHJGH_RS30890	COG2205	protein histidine kinase activity
SHJGH_RS30910	COG3285	dna ligase
SHJGH_RS30910	COG1793	dna ligase
SHJGH_RS30915	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SHJGH_RS30990	COG2188	Transcriptional regulator
SHJGH_RS31035	COG0018	arginyl-trna synthetase
SHJGH_RS31040	COG0019	diaminopimelate decarboxylase activity
SHJGH_RS31045	COG0460	homoserine dehydrogenase
SHJGH_RS31050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SHJGH_RS31055	COG0083	homoserine kinase activity
SHJGH_RS31070	COG0254	rRNA binding
SHJGH_RS31075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SHJGH_RS31080	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJGH_RS31090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SHJGH_RS31095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SHJGH_RS31100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SHJGH_RS31115	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SHJGH_RS31120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SHJGH_RS31125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SHJGH_RS31130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SHJGH_RS31135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SHJGH_RS31140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SHJGH_RS31145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SHJGH_RS31160	COG2197	response regulator
SHJGH_RS31165	COG4585	Histidine kinase
SHJGH_RS31175	COG2318	DinB family
SHJGH_RS31185	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJGH_RS31200	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SHJGH_RS31260	COG0183	Belongs to the thiolase family
SHJGH_RS31330	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJGH_RS31330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJGH_RS31365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SHJGH_RS31370	COG0857	belongs to the CobB CobQ family
SHJGH_RS31370	COG0280	phosphate acetyltransferase
SHJGH_RS31375	COG0205	6-phosphofructokinase activity
SHJGH_RS31380	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS31385	COG1175	transmembrane transport
SHJGH_RS31395	COG3903	Transcriptional regulator
SHJGH_RS31395	COG3629	intracellular signal transduction
SHJGH_RS31400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SHJGH_RS31415	COG4565	transcriptional regulatory protein
SHJGH_RS31420	COG3290	protein histidine kinase activity
SHJGH_RS31425	COG1301	dicarboxylic acid transport
SHJGH_RS31435	COG0477	Major facilitator Superfamily
SHJGH_RS31455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SHJGH_RS31460	COG3281	Trehalose synthase
SHJGH_RS31470	COG0366	Alpha amylase catalytic
SHJGH_RS31475	COG0058	SHG alpha-glucan phosphorylase activity
SHJGH_RS31505	COG1132	(ABC) transporter
SHJGH_RS31510	COG1132	(ABC) transporter
SHJGH_RS31515	COG1132	(ABC) transporter
SHJGH_RS31520	COG1132	(ABC) transporter
SHJGH_RS31550	COG1376	ErfK ybiS ycfS ynhG family protein
SHJGH_RS31555	COG1376	ErfK ybiS ycfS ynhG family protein
SHJGH_RS31585	COG0789	Transcriptional regulator
SHJGH_RS31595	COG1119	ATPase activity
SHJGH_RS31600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SHJGH_RS31620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SHJGH_RS31645	COG1760	l-serine dehydratase
SHJGH_RS31650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SHJGH_RS31655	COG0509	glycine decarboxylation via glycine cleavage system
SHJGH_RS31660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SHJGH_RS31680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SHJGH_RS31685	COG0747	negative chemotaxis
SHJGH_RS31695	COG0444	Belongs to the ABC transporter superfamily
SHJGH_RS31700	COG4608	Belongs to the ABC transporter superfamily
SHJGH_RS31710	COG2860	membrane
SHJGH_RS31730	COG2378	regulation of single-species biofilm formation
SHJGH_RS31760	COG0482	sulfurtransferase activity
SHJGH_RS31775	COG1611	Belongs to the LOG family
SHJGH_RS31780	COG4221	oxidoreductase activity
SHJGH_RS31790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SHJGH_RS31815	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SHJGH_RS31820	COG0154	amidase activity
SHJGH_RS31830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SHJGH_RS31840	COG2409	Drug exporters of the RND superfamily
SHJGH_RS31845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SHJGH_RS31860	COG2197	response regulator
SHJGH_RS31870	COG2133	pyrroloquinoline quinone binding
SHJGH_RS31875	COG0667	Aldo Keto reductase
SHJGH_RS31885	COG5001	Diguanylate cyclase
SHJGH_RS31895	COG0440	acetolactate synthase activity
SHJGH_RS31900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SHJGH_RS31905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SHJGH_RS31910	COG0477	Major facilitator Superfamily
SHJGH_RS31920	COG2508	Transcriptional regulator
SHJGH_RS31925	COG0506	proline dehydrogenase activity
SHJGH_RS31930	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS31940	COG2130	NADP-dependent
SHJGH_RS31945	COG0583	DNA-binding transcription factor activity
SHJGH_RS31955	COG0473	3-isopropylmalate dehydrogenase activity
SHJGH_RS31960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SHJGH_RS31965	COG0832	Belongs to the urease beta subunit family
SHJGH_RS31965	COG0831	urea catabolic process
SHJGH_RS31970	COG0804	urea catabolic process
SHJGH_RS31975	COG2957	Belongs to the agmatine deiminase family
SHJGH_RS31985	COG0477	Major facilitator Superfamily
SHJGH_RS31990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SHJGH_RS32040	COG2353	YceI-like domain
SHJGH_RS32050	COG5492	domain, Protein
SHJGH_RS32055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SHJGH_RS32075	COG2018	Roadblock/LC7 domain
SHJGH_RS32095	COG2018	Roadblock/LC7 domain
SHJGH_RS32100	COG5002	protein histidine kinase activity
SHJGH_RS32110	COG0179	Fumarylacetoacetate (FAA) hydrolase
SHJGH_RS32115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SHJGH_RS32165	COG1414	Transcriptional regulator
SHJGH_RS32170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SHJGH_RS32175	COG0066	3-isopropylmalate dehydratase activity
SHJGH_RS32185	COG0776	regulation of translation
SHJGH_RS32195	COG1920	GTP binding
SHJGH_RS32205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SHJGH_RS32210	COG1181	Belongs to the D-alanine--D-alanine ligase family
SHJGH_RS32230	COG0351	phosphomethylpyrimidine kinase
SHJGH_RS32245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SHJGH_RS32250	COG1461	Dihydroxyacetone kinase
SHJGH_RS32260	COG0326	Molecular chaperone. Has ATPase activity
SHJGH_RS32270	COG0742	ribosomal rna small subunit methyltransferase
SHJGH_RS32275	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SHJGH_RS32290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SHJGH_RS32295	COG0571	ribonuclease III activity
SHJGH_RS32300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SHJGH_RS32305	COG1733	regulation of RNA biosynthetic process
SHJGH_RS32310	COG0655	NAD(P)H dehydrogenase (quinone) activity
SHJGH_RS32320	COG1254	Belongs to the acylphosphatase family
SHJGH_RS32330	COG1196	nuclear chromosome segregation
SHJGH_RS32335	COG0477	Major facilitator Superfamily
SHJGH_RS32375	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SHJGH_RS32385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SHJGH_RS32400	COG0228	four-way junction DNA binding
SHJGH_RS32405	COG1837	Belongs to the UPF0109 family
SHJGH_RS32410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SHJGH_RS32415	COG0336	Belongs to the RNA methyltransferase TrmD family
SHJGH_RS32420	COG0335	large ribosomal subunit rRNA binding
SHJGH_RS32435	COG0681	Belongs to the peptidase S26 family
SHJGH_RS32455	COG0792	nuclease activity
SHJGH_RS32470	COG1191	sigma factor activity
SHJGH_RS32485	COG0052	Belongs to the universal ribosomal protein uS2 family
SHJGH_RS32490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SHJGH_RS32495	COG0528	UMP kinase activity
SHJGH_RS32500	COG0233	cytoplasmic translational termination
SHJGH_RS32505	COG0575	Belongs to the CDS family
SHJGH_RS32510	COG2124	cytochrome p450
SHJGH_RS32520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SHJGH_RS32530	COG4208	sulfate ABC transporter
SHJGH_RS32535	COG3842	ATPase activity
SHJGH_RS32565	COG4181	ATPase activity
SHJGH_RS32570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SHJGH_RS32580	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS32595	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS32600	COG1175	transmembrane transport
SHJGH_RS32615	COG3876	Protein conserved in bacteria
SHJGH_RS32625	COG1414	Transcriptional regulator
SHJGH_RS32645	COG0584	glycerophosphoryl diester phosphodiesterase
SHJGH_RS32650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SHJGH_RS32675	COG3842	ATPase activity
SHJGH_RS32680	COG1176	ABC-type spermidine putrescine transport system, permease component I
SHJGH_RS32685	COG1177	transmembrane transport
SHJGH_RS32690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJGH_RS32725	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS32755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SHJGH_RS32760	COG0750	zinc metalloprotease
SHJGH_RS32765	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SHJGH_RS32775	COG1247	-acetyltransferase
SHJGH_RS32780	COG0442	prolyl-tRNA aminoacylation
SHJGH_RS32800	COG0779	Required for maturation of 30S ribosomal subunits
SHJGH_RS32810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SHJGH_RS32820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SHJGH_RS32825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SHJGH_RS32840	COG0455	bacterial-type flagellum organization
SHJGH_RS32855	COG3266	domain, Protein
SHJGH_RS32860	COG1404	Belongs to the peptidase S8 family
SHJGH_RS32895	COG1404	Belongs to the peptidase S8 family
SHJGH_RS32915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJGH_RS32915	COG0515	serine threonine protein kinase
SHJGH_RS32920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJGH_RS32920	COG0515	serine threonine protein kinase
SHJGH_RS32925	COG1674	ftsk spoiiie
SHJGH_RS32940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SHJGH_RS32945	COG1185	polyribonucleotide nucleotidyltransferase activity
SHJGH_RS32950	COG0612	Peptidase, M16
SHJGH_RS32955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SHJGH_RS32975	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SHJGH_RS32980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJGH_RS32985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SHJGH_RS33015	COG2770	Histidine kinase
SHJGH_RS33015	COG2208	phosphoserine phosphatase activity
SHJGH_RS33020	COG2205	protein histidine kinase activity
SHJGH_RS33020	COG0784	Response regulator, receiver
SHJGH_RS33030	COG1674	ftsk spoiiie
SHJGH_RS33040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SHJGH_RS33050	COG1546	Belongs to the CinA family
SHJGH_RS33050	COG1058	Belongs to the CinA family
SHJGH_RS33055	COG1396	sequence-specific DNA binding
SHJGH_RS33060	COG0783	Belongs to the Dps family
SHJGH_RS33070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SHJGH_RS33075	COG1201	RNA secondary structure unwinding
SHJGH_RS33105	COG0628	permease
SHJGH_RS33120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SHJGH_RS33150	COG0765	amino acid transport
SHJGH_RS33155	COG0765	amino acid transport
SHJGH_RS33160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJGH_RS33165	COG1126	abc transporter atp-binding protein
SHJGH_RS33170	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS33175	COG2205	protein histidine kinase activity
SHJGH_RS33180	COG2358	TRAP transporter, solute receptor (TAXI family
SHJGH_RS33215	COG0475	glutathione-regulated potassium exporter activity
SHJGH_RS33220	COG3469	chitinase activity
SHJGH_RS33240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SHJGH_RS33260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SHJGH_RS33270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SHJGH_RS33275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SHJGH_RS33285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SHJGH_RS33315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SHJGH_RS33320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SHJGH_RS33325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SHJGH_RS33340	COG0588	phosphoglycerate mutase activity
SHJGH_RS33360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SHJGH_RS33400	COG2186	Transcriptional regulator
SHJGH_RS33405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SHJGH_RS33410	COG5640	endopeptidase activity
SHJGH_RS33420	COG0187	DNA topoisomerase II activity
SHJGH_RS33430	COG4585	Histidine kinase
SHJGH_RS33435	COG2197	response regulator
SHJGH_RS33445	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJGH_RS33460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SHJGH_RS33475	COG4565	transcriptional regulatory protein
SHJGH_RS33480	COG3290	protein histidine kinase activity
SHJGH_RS33495	COG0372	Belongs to the citrate synthase family
SHJGH_RS33500	COG0523	cobalamin synthesis protein
SHJGH_RS33505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SHJGH_RS33510	COG0612	Peptidase, M16
SHJGH_RS33525	COG1802	Transcriptional regulator
SHJGH_RS33530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SHJGH_RS33555	COG1435	thymidine kinase activity
SHJGH_RS33590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SHJGH_RS33595	COG0483	inositol monophosphate 1-phosphatase activity
SHJGH_RS33600	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS33605	COG2205	protein histidine kinase activity
SHJGH_RS33630	COG0756	dUTP diphosphatase activity
SHJGH_RS33640	COG1136	(ABC) transporter
SHJGH_RS33670	COG0569	domain protein
SHJGH_RS33675	COG0531	amino acid
SHJGH_RS33680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SHJGH_RS33725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SHJGH_RS33740	COG1215	transferase activity, transferring glycosyl groups
SHJGH_RS33750	COG4310	Domain of unknown function (DUF2172)
SHJGH_RS33765	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SHJGH_RS33775	COG0438	transferase activity, transferring glycosyl groups
SHJGH_RS33800	COG0367	asparagine synthase
SHJGH_RS33820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SHJGH_RS33860	COG1799	cell septum assembly
SHJGH_RS33865	COG0443	Heat shock 70 kDa protein
SHJGH_RS33920	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJGH_RS33925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SHJGH_RS33965	COG2235	arginine
SHJGH_RS33970	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SHJGH_RS33975	COG0531	amino acid
SHJGH_RS33985	COG1024	Enoyl-CoA hydratase
SHJGH_RS34020	COG2188	Transcriptional regulator
SHJGH_RS34025	COG2182	Extracellular solute-binding protein
SHJGH_RS34030	COG1175	transmembrane transport
SHJGH_RS34035	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS34040	COG1472	Belongs to the glycosyl hydrolase 3 family
SHJGH_RS34070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJGH_RS34085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS34100	COG1595	DNA-templated transcription, initiation
SHJGH_RS34110	COG1309	transcriptional regulator
SHJGH_RS34115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SHJGH_RS34120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SHJGH_RS34125	COG3290	protein histidine kinase activity
SHJGH_RS34130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHJGH_RS34135	COG0443	Heat shock 70 kDa protein
SHJGH_RS34140	COG0484	heat shock protein binding
SHJGH_RS34150	COG3537	Alpha-1,2-mannosidase
SHJGH_RS34160	COG1653	transport
SHJGH_RS34165	COG1175	transmembrane transport
SHJGH_RS34170	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS34175	COG1940	carbohydrate kinase activity
SHJGH_RS34180	COG4213	ABC transporter substrate-binding protein
SHJGH_RS34190	COG4214	carbohydrate transport
SHJGH_RS34195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SHJGH_RS34200	COG0531	amino acid
SHJGH_RS34225	COG1024	Enoyl-CoA hydratase
SHJGH_RS34225	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJGH_RS34230	COG0183	Belongs to the thiolase family
SHJGH_RS34235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SHJGH_RS34250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SHJGH_RS34265	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJGH_RS34275	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SHJGH_RS34280	COG3253	May function as heme-dependent peroxidase
SHJGH_RS34300	COG3220	belongs to the UPF0276 family
SHJGH_RS34315	COG4152	abc transporter atp-binding protein
SHJGH_RS34335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJGH_RS34335	COG0723	plastoquinol--plastocyanin reductase activity
SHJGH_RS34340	COG2326	polyphosphate kinase activity
SHJGH_RS34345	COG0330	HflC and HflK could
SHJGH_RS34380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SHJGH_RS34385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SHJGH_RS34400	COG1174	glycine betaine transport
SHJGH_RS34420	COG2018	Roadblock/LC7 domain
SHJGH_RS34430	COG1732	Glycine betaine
SHJGH_RS34435	COG2986	histidine ammonia-lyase
SHJGH_RS34445	COG0640	Transcriptional regulator
SHJGH_RS34545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SHJGH_RS34550	COG0583	DNA-binding transcription factor activity
SHJGH_RS34590	COG1175	transmembrane transport
SHJGH_RS34615	COG2409	Drug exporters of the RND superfamily
SHJGH_RS34620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SHJGH_RS34625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SHJGH_RS34650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SHJGH_RS34655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SHJGH_RS34655	COG1116	anion transmembrane transporter activity
SHJGH_RS34680	COG0529	Catalyzes the synthesis of activated sulfate
SHJGH_RS34685	COG0175	sulfate reduction
SHJGH_RS34700	COG0456	acetyltransferase
SHJGH_RS34715	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS34745	COG3739	integral membrane protein
SHJGH_RS34775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SHJGH_RS34795	COG2040	homocysteine
SHJGH_RS34800	COG3940	Belongs to the glycosyl hydrolase 43 family
SHJGH_RS34865	COG1162	GTPase activity
SHJGH_RS34875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SHJGH_RS34895	COG0028	Belongs to the TPP enzyme family
SHJGH_RS34915	COG1802	Transcriptional regulator
SHJGH_RS34925	COG3835	regulator
SHJGH_RS34940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SHJGH_RS34945	COG2252	PERMEase
SHJGH_RS34965	COG5634	Uncharacterized conserved protein (DUF2278)
SHJGH_RS34980	COG0515	serine threonine protein kinase
SHJGH_RS34995	COG1653	transport
SHJGH_RS35015	COG2197	response regulator
SHJGH_RS35020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJGH_RS35025	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS35035	COG3960	tartronate-semialdehyde synthase activity
SHJGH_RS35055	COG0753	catalase activity
SHJGH_RS35060	COG2084	Dehydrogenase
SHJGH_RS35065	COG3622	Belongs to the hyi family
SHJGH_RS35085	COG2351	hydroxyisourate hydrolase activity
SHJGH_RS35095	COG2233	PERMEase
SHJGH_RS35105	COG2233	PERMEase
SHJGH_RS35115	COG1733	regulation of RNA biosynthetic process
SHJGH_RS35130	COG0406	alpha-ribazole phosphatase activity
SHJGH_RS35145	COG0436	Aminotransferase
SHJGH_RS35150	COG1733	regulation of RNA biosynthetic process
SHJGH_RS35175	COG4264	IucA IucC family
SHJGH_RS35190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SHJGH_RS35210	COG1414	Transcriptional regulator
SHJGH_RS35215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SHJGH_RS35220	COG4266	Belongs to the allantoicase family
SHJGH_RS35255	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS35260	COG2188	Transcriptional regulator
SHJGH_RS35280	COG1940	carbohydrate kinase activity
SHJGH_RS35290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SHJGH_RS35370	COG1063	alcohol dehydrogenase
SHJGH_RS35375	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SHJGH_RS35380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SHJGH_RS35385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SHJGH_RS35395	COG0640	Transcriptional regulator
SHJGH_RS35405	COG2814	Major facilitator Superfamily
SHJGH_RS35415	COG0514	ATP-dependent DNA helicase (RecQ)
SHJGH_RS35425	COG0604	alcohol dehydrogenase
SHJGH_RS35470	COG3903	Transcriptional regulator
SHJGH_RS35470	COG3629	intracellular signal transduction
SHJGH_RS35505	COG1271	oxidase subunit
SHJGH_RS35535	COG1024	Enoyl-CoA hydratase
SHJGH_RS35545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SHJGH_RS35550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SHJGH_RS35555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SHJGH_RS35560	COG0254	rRNA binding
SHJGH_RS35570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SHJGH_RS35575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SHJGH_RS35580	COG0456	acetyltransferase
SHJGH_RS35605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SHJGH_RS35625	COG0628	permease
SHJGH_RS35630	COG1597	lipid kinase activity
SHJGH_RS35640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJGH_RS35660	COG0765	amino acid transport
SHJGH_RS35675	COG0405	Gamma-glutamyltransferase
SHJGH_RS35680	COG0542	response to heat
SHJGH_RS35685	COG0024	Methionine aminopeptidase
SHJGH_RS35705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SHJGH_RS35720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SHJGH_RS35725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS35730	COG1953	Uracil, thiamine, allantoin
SHJGH_RS35755	COG0095	Lipoate-protein ligase
SHJGH_RS35760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SHJGH_RS35780	COG0483	inositol monophosphate 1-phosphatase activity
SHJGH_RS35800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SHJGH_RS35815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SHJGH_RS35845	COG1929	Belongs to the glycerate kinase type-1 family
SHJGH_RS35855	COG0688	phosphatidylethanolamine metabolic process
SHJGH_RS35860	COG1960	acyl-CoA dehydrogenase activity
SHJGH_RS35870	COG2301	Belongs to the HpcH HpaI aldolase family
SHJGH_RS35875	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJGH_RS35875	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SHJGH_RS35890	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJGH_RS35900	COG0456	acetyltransferase
SHJGH_RS35930	COG2208	phosphoserine phosphatase activity
SHJGH_RS35930	COG2172	sigma factor antagonist activity
SHJGH_RS35930	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJGH_RS35935	COG4106	trans-aconitate 2-methyltransferase activity
SHJGH_RS35940	COG2362	D-Aminopeptidase
SHJGH_RS35945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SHJGH_RS35955	COG1619	proteins homologs of microcin C7 resistance protein MccF
SHJGH_RS35975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS35990	COG1793	dna ligase
SHJGH_RS35990	COG3285	dna ligase
SHJGH_RS36060	COG0406	alpha-ribazole phosphatase activity
SHJGH_RS36065	COG0488	(ABC) transporter
SHJGH_RS36080	COG0693	protein deglycase activity
SHJGH_RS36095	COG0028	Belongs to the TPP enzyme family
SHJGH_RS36120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SHJGH_RS36155	COG2154	pterin-4-alpha-carbinolamine dehydratase
SHJGH_RS36160	COG2226	methyltransferase
SHJGH_RS36190	COG4733	cellulase activity
SHJGH_RS36190	COG5297	Belongs to the glycosyl hydrolase family 6
SHJGH_RS36200	COG5297	Belongs to the glycosyl hydrolase family 6
SHJGH_RS36210	COG4106	trans-aconitate 2-methyltransferase activity
SHJGH_RS36215	COG4221	oxidoreductase activity
SHJGH_RS36230	COG0656	L-ascorbic acid biosynthetic process
SHJGH_RS36235	COG1022	Amp-dependent synthetase and ligase
SHJGH_RS36260	COG1846	Transcriptional regulator
SHJGH_RS36265	COG1335	isochorismatase
SHJGH_RS36270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SHJGH_RS36280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHJGH_RS36285	COG3383	formate dehydrogenase (NAD+) activity
SHJGH_RS36290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SHJGH_RS36300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJGH_RS36330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJGH_RS36340	COG0045	succinate-CoA ligase (ADP-forming) activity
SHJGH_RS36350	COG1012	belongs to the aldehyde dehydrogenase family
SHJGH_RS36365	COG2182	Extracellular solute-binding protein
SHJGH_RS36370	COG1175	transmembrane transport
SHJGH_RS36375	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS36380	COG2723	6-phospho-beta-galactosidase activity
SHJGH_RS36385	COG2273	Hydrolase Family 16
SHJGH_RS36485	COG0297	glycogen (starch) synthase activity
SHJGH_RS36505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SHJGH_RS36530	COG0477	Major facilitator Superfamily
SHJGH_RS36540	COG3467	pyridoxamine 5'-phosphate
SHJGH_RS36545	COG2084	Dehydrogenase
SHJGH_RS36555	COG0477	Major facilitator Superfamily
SHJGH_RS36565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SHJGH_RS36570	COG1082	Xylose isomerase domain protein TIM barrel
SHJGH_RS36570	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SHJGH_RS36580	COG0588	phosphoglycerate mutase activity
SHJGH_RS36585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SHJGH_RS36590	COG0166	Belongs to the GPI family
SHJGH_RS36605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SHJGH_RS36630	COG1486	melibiose metabolic process
SHJGH_RS36635	COG3469	chitinase activity
SHJGH_RS36645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SHJGH_RS36685	COG1175	transmembrane transport
SHJGH_RS36690	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS36695	COG0366	Alpha amylase catalytic
SHJGH_RS36705	COG3511	phospholipase C
SHJGH_RS36735	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SHJGH_RS36735	COG1672	PFAM Archaeal ATPase
SHJGH_RS36745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJGH_RS36755	COG3485	protocatechuate 3,4-dioxygenase
SHJGH_RS36760	COG3485	protocatechuate 3,4-dioxygenase
SHJGH_RS36780	COG1793	dna ligase
SHJGH_RS36810	COG1834	amidinotransferase
SHJGH_RS36815	COG0488	(ABC) transporter
SHJGH_RS36840	COG1515	deoxyribonuclease V activity
SHJGH_RS36845	COG3268	Saccharopine dehydrogenase
SHJGH_RS36850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SHJGH_RS36855	COG0183	Belongs to the thiolase family
SHJGH_RS36860	COG1024	Enoyl-CoA hydratase
SHJGH_RS36860	COG1250	3-hydroxyacyl-CoA dehydrogenase
SHJGH_RS36870	COG1113	amino acid transport
SHJGH_RS36875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SHJGH_RS36890	COG2936	dipeptidyl-peptidase activity
SHJGH_RS36900	COG0488	(ABC) transporter
SHJGH_RS36905	COG2183	response to ionizing radiation
SHJGH_RS36910	COG1024	Enoyl-CoA hydratase
SHJGH_RS36920	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SHJGH_RS36965	COG1134	teichoic acid transport
SHJGH_RS36970	COG1562	ergosterol biosynthetic process
SHJGH_RS36980	COG1233	COG1233 Phytoene dehydrogenase and related
SHJGH_RS36990	COG1657	PFAM Prenyltransferase squalene oxidase
SHJGH_RS37005	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SHJGH_RS37010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SHJGH_RS37040	COG2755	lipolytic protein G-D-S-L family
SHJGH_RS37050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SHJGH_RS37085	COG1063	alcohol dehydrogenase
SHJGH_RS37090	COG0156	8-amino-7-oxononanoate synthase activity
SHJGH_RS37095	COG0583	DNA-binding transcription factor activity
SHJGH_RS37120	COG3958	Transketolase
SHJGH_RS37125	COG3959	Transketolase, thiamine diphosphate binding domain
SHJGH_RS37155	COG0561	phosphatase activity
SHJGH_RS37175	COG0783	Belongs to the Dps family
SHJGH_RS37180	COG2267	carboxylic ester hydrolase activity
SHJGH_RS37185	COG0183	Belongs to the thiolase family
SHJGH_RS37190	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS37200	COG0546	phosphoglycolate phosphatase activity
SHJGH_RS37235	COG0726	polysaccharide deacetylase
SHJGH_RS37250	COG1653	transport
SHJGH_RS37255	COG1175	transmembrane transport
SHJGH_RS37265	COG1472	Belongs to the glycosyl hydrolase 3 family
SHJGH_RS37285	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS37290	COG1175	transmembrane transport
SHJGH_RS37295	COG1653	transport
SHJGH_RS37300	COG2188	Transcriptional regulator
SHJGH_RS37330	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS37335	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS37345	COG1609	Transcriptional regulator
SHJGH_RS37350	COG0673	inositol 2-dehydrogenase activity
SHJGH_RS37355	COG1609	Transcriptional regulator
SHJGH_RS37375	COG0477	Major facilitator Superfamily
SHJGH_RS37395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SHJGH_RS37400	COG3275	phosphorelay sensor kinase activity
SHJGH_RS37405	COG0531	amino acid
SHJGH_RS37415	COG3938	Belongs to the proline racemase family
SHJGH_RS37420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SHJGH_RS37425	COG0446	pyridine nucleotide-disulphide oxidoreductase
SHJGH_RS37435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SHJGH_RS37450	COG1126	abc transporter atp-binding protein
SHJGH_RS37455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SHJGH_RS37460	COG0456	acetyltransferase
SHJGH_RS37465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS37470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS37475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS37485	COG2197	response regulator
SHJGH_RS37515	COG2838	Isocitrate dehydrogenase
SHJGH_RS37525	COG0668	transmembrane transport
SHJGH_RS37530	COG0531	amino acid
SHJGH_RS37540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SHJGH_RS37555	COG1024	Enoyl-CoA hydratase
SHJGH_RS37565	COG1132	(ABC) transporter
SHJGH_RS37575	COG2080	2 iron, 2 sulfur cluster binding
SHJGH_RS37580	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SHJGH_RS37585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SHJGH_RS37615	COG1335	isochorismatase
SHJGH_RS37645	COG0655	NAD(P)H dehydrogenase (quinone) activity
SHJGH_RS37655	COG0477	Major facilitator Superfamily
SHJGH_RS37665	COG0583	DNA-binding transcription factor activity
SHJGH_RS37670	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS37675	COG1309	transcriptional regulator
SHJGH_RS37710	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SHJGH_RS37720	COG2815	serine threonine protein kinase
SHJGH_RS37720	COG0515	serine threonine protein kinase
SHJGH_RS37725	COG0515	serine threonine protein kinase
SHJGH_RS37730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SHJGH_RS37835	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SHJGH_RS37835	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SHJGH_RS37840	COG0210	DNA helicase
SHJGH_RS37860	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SHJGH_RS37870	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SHJGH_RS37890	COG0297	glycogen (starch) synthase activity
SHJGH_RS37895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SHJGH_RS37900	COG3537	Alpha-1,2-mannosidase
SHJGH_RS37930	COG2186	Transcriptional regulator
SHJGH_RS37940	COG1129	ABC transporter
SHJGH_RS37950	COG4948	Mandelate Racemase Muconate Lactonizing
SHJGH_RS37985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SHJGH_RS38010	COG0531	amino acid
SHJGH_RS38025	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SHJGH_RS38025	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SHJGH_RS38030	COG0726	polysaccharide deacetylase
SHJGH_RS38065	COG0583	DNA-binding transcription factor activity
SHJGH_RS38075	COG0583	DNA-binding transcription factor activity
SHJGH_RS38085	COG1053	succinate dehydrogenase
SHJGH_RS38090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SHJGH_RS38115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SHJGH_RS38125	COG3360	Dodecin
SHJGH_RS38130	COG2182	Extracellular solute-binding protein
SHJGH_RS38135	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SHJGH_RS38140	COG0121	glutamine amidotransferase
SHJGH_RS38180	COG2268	Band 7 protein
SHJGH_RS38225	COG1609	Transcriptional regulator
SHJGH_RS38230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SHJGH_RS38240	COG0242	peptide deformylase activity
SHJGH_RS38250	COG1793	dna ligase
SHJGH_RS38300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SHJGH_RS38415	COG0210	DNA helicase
SHJGH_RS38455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SHJGH_RS38480	COG3328	transposase activity
SHJGH_RS38655	COG3336	cytochrome c oxidase
SHJGH_RS38670	COG0753	catalase activity
SHJGH_RS38705	COG0745	RESPONSE REGULATOR receiver
SHJGH_RS38710	COG5002	protein histidine kinase activity
SHJGH_RS38720	COG1595	DNA-templated transcription, initiation
SHJGH_RS38730	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS38735	COG1175	transmembrane transport
SHJGH_RS38740	COG2182	Extracellular solute-binding protein
SHJGH_RS38745	COG1501	Belongs to the glycosyl hydrolase 31 family
SHJGH_RS38765	COG0753	catalase activity
SHJGH_RS38785	COG0584	glycerophosphoryl diester phosphodiesterase
SHJGH_RS38790	COG1785	Belongs to the alkaline phosphatase family
SHJGH_RS38830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SHJGH_RS38855	COG0542	response to heat
SHJGH_RS38870	COG1174	glycine betaine transport
SHJGH_RS38890	COG1556	Lactate utilization protein
SHJGH_RS38895	COG1139	Iron-sulfur cluster binding protein
SHJGH_RS38900	COG0247	lactate metabolic process
SHJGH_RS38905	COG1070	Carbohydrate kinase
SHJGH_RS38910	COG3347	Dehydrogenase
SHJGH_RS38910	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS38920	COG1129	ABC transporter
SHJGH_RS38925	COG1172	Belongs to the binding-protein-dependent transport system permease family
SHJGH_RS38955	COG1609	Transcriptional regulator
SHJGH_RS38965	COG1357	PFAM Pentapeptide repeats (8 copies)
SHJGH_RS38975	COG1309	transcriptional regulator
SHJGH_RS38990	COG2706	6-phosphogluconolactonase activity
SHJGH_RS39045	COG0546	phosphoglycolate phosphatase activity
SHJGH_RS39050	COG1796	DNA polymerase
SHJGH_RS39050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SHJGH_RS39055	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS39100	COG1006	Multisubunit Na H antiporter MnhC subunit
SHJGH_RS39105	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SHJGH_RS39150	COG0435	Glutathione S-transferase
SHJGH_RS39170	COG2124	cytochrome p450
SHJGH_RS39185	COG0667	Aldo Keto reductase
SHJGH_RS39220	COG1595	DNA-templated transcription, initiation
SHJGH_RS39230	COG3250	beta-galactosidase activity
SHJGH_RS39270	COG2890	protein-(glutamine-N5) methyltransferase activity
SHJGH_RS39285	COG0300	oxidoreductase activity
SHJGH_RS39295	COG0726	polysaccharide deacetylase
SHJGH_RS39315	COG2274	protein secretion by the type I secretion system
SHJGH_RS39350	COG2124	cytochrome p450
SHJGH_RS39370	COG3251	PFAM MbtH domain protein
SHJGH_RS39410	COG0477	Major facilitator Superfamily
SHJGH_RS39420	COG0247	lactate metabolic process
SHJGH_RS39420	COG0277	FAD linked oxidase domain protein
SHJGH_RS39425	COG0300	oxidoreductase activity
SHJGH_RS39450	COG0596	Alpha beta hydrolase
SHJGH_RS39455	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS39465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SHJGH_RS39500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SHJGH_RS39515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SHJGH_RS39540	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS39545	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS39560	COG1846	Transcriptional regulator
SHJGH_RS39560	COG1940	carbohydrate kinase activity
SHJGH_RS39600	COG1309	transcriptional regulator
SHJGH_RS39620	COG0367	asparagine synthase
SHJGH_RS39695	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SHJGH_RS39710	COG3387	PFAM Glycoside hydrolase 15-related
SHJGH_RS39730	COG3290	protein histidine kinase activity
SHJGH_RS39745	COG2045	Belongs to the ComB family
SHJGH_RS39775	COG0456	acetyltransferase
SHJGH_RS39850	COG0667	Aldo Keto reductase
SHJGH_RS39860	COG2124	cytochrome p450
SHJGH_RS39890	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SHJGH_RS39915	COG0248	Ppx GppA phosphatase
SHJGH_RS39945	COG1982	Orn Lys Arg decarboxylase major
SHJGH_RS39965	COG2172	sigma factor antagonist activity
SHJGH_RS39970	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJGH_RS39975	COG1366	Belongs to the anti-sigma-factor antagonist family
SHJGH_RS40025	COG2197	response regulator
SHJGH_RS40035	COG0583	DNA-binding transcription factor activity
SHJGH_RS40060	COG0531	amino acid
SHJGH_RS40075	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS40095	COG0596	Alpha beta hydrolase
SHJGH_RS40105	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS40125	COG2267	carboxylic ester hydrolase activity
SHJGH_RS40130	COG2755	lipolytic protein G-D-S-L family
SHJGH_RS40140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SHJGH_RS40155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SHJGH_RS40180	COG1177	transmembrane transport
SHJGH_RS40185	COG1176	ABC-type spermidine putrescine transport system, permease component I
SHJGH_RS40190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SHJGH_RS40195	COG3842	ATPase activity
SHJGH_RS40210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SHJGH_RS40215	COG1733	regulation of RNA biosynthetic process
SHJGH_RS40260	COG0277	FAD linked oxidase domain protein
SHJGH_RS40265	COG1597	lipid kinase activity
SHJGH_RS40275	COG0542	response to heat
SHJGH_RS40285	COG4106	trans-aconitate 2-methyltransferase activity
SHJGH_RS40290	COG0640	Transcriptional regulator
SHJGH_RS40295	COG1316	TRANSCRIPTIONal
SHJGH_RS40315	COG2814	Major facilitator Superfamily
SHJGH_RS40335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SHJGH_RS40340	COG2409	Drug exporters of the RND superfamily
SHJGH_RS40370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SHJGH_RS40395	COG1175	transmembrane transport
SHJGH_RS40400	COG2182	Extracellular solute-binding protein
SHJGH_RS40425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SHJGH_RS40430	COG1132	(ABC) transporter
SHJGH_RS40440	COG1271	oxidase subunit
SHJGH_RS40445	COG0783	Belongs to the Dps family
SHJGH_RS40485	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SHJGH_RS40485	COG3608	succinylglutamate desuccinylase aspartoacylase
SHJGH_RS40490	COG0028	Belongs to the TPP enzyme family
SHJGH_RS40505	COG3619	membrane
SHJGH_RS40510	COG2259	Doxx family
SHJGH_RS40515	COG1335	isochorismatase
SHJGH_RS40520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SHJGH_RS40545	COG0515	serine threonine protein kinase
SHJGH_RS40545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHJGH_RS40570	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SHJGH_RS40570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SHJGH_RS40600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SHJGH_RS40610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SHJGH_RS40615	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SHJGH_RS40620	COG1082	Xylose isomerase domain protein TIM barrel
SHJGH_RS40640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SHJGH_RS40665	COG0326	Molecular chaperone. Has ATPase activity
SHJGH_RS40695	COG0583	DNA-binding transcription factor activity
SHJGH_RS40785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SHJGH_RS40790	COG1120	ATPase activity
SHJGH_RS40800	COG5640	endopeptidase activity
SHJGH_RS40805	COG0583	DNA-binding transcription factor activity
SHJGH_RS40815	COG3345	alpha-galactosidase
SHJGH_RS40825	COG1175	transmembrane transport
SHJGH_RS40830	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS40845	COG2186	Transcriptional regulator
SHJGH_RS40850	COG4948	Mandelate Racemase Muconate Lactonizing
SHJGH_RS40860	COG0800	Aldolase
SHJGH_RS40865	COG3386	PFAM SMP-30 Gluconolaconase
SHJGH_RS40880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SHJGH_RS40885	COG0110	maltose O-acetyltransferase activity
SHJGH_RS40890	COG0318	PFAM AMP-dependent synthetase and ligase
SHJGH_RS40895	COG0492	ferredoxin-NADP+ reductase activity
SHJGH_RS40910	COG0475	glutathione-regulated potassium exporter activity
SHJGH_RS40940	COG0395	ABC-type sugar transport system, permease component
SHJGH_RS40955	COG1609	Transcriptional regulator
SHJGH_RS40960	COG0583	DNA-binding transcription factor activity
SHJGH_RS40995	COG2319	Wd-40 repeat
SHJGH_RS40995	COG4249	Peptidase C14 caspase catalytic subunit p20
SHJGH_RS41035	COG2154	pterin-4-alpha-carbinolamine dehydratase
SHJGH_RS41055	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS41075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SHJGH_RS41080	COG1660	Displays ATPase and GTPase activities
SHJGH_RS41090	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SHJGH_RS41100	COG2226	methyltransferase
SHJGH_RS41105	COG3623	hexulose-6-phosphate isomerase
SHJGH_RS41125	COG1063	alcohol dehydrogenase
SHJGH_RS41130	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SHJGH_RS41150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SHJGH_RS41160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SHJGH_RS41180	COG0431	NADPH-dependent FMN reductase
SHJGH_RS41215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJGH_RS41245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SHJGH_RS41315	COG3851	Histidine kinase
SHJGH_RS41320	COG2197	response regulator
SHJGH_RS41325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SHJGH_RS41380	COG1733	regulation of RNA biosynthetic process
SHJGH_RS41405	COG0583	DNA-binding transcription factor activity
SHJGH_RS41420	COG1397	ADP-ribosylglycohydrolase
SHJGH_RS41495	COG0596	Alpha beta hydrolase
SHJGH_RS41500	COG1595	DNA-templated transcription, initiation
SHJGH_RS41510	COG1278	Cold shock
SHJGH_RS41555	COG2508	Transcriptional regulator
SHJGH_RS41560	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS41570	COG0179	Fumarylacetoacetate (FAA) hydrolase
SHJGH_RS41585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SHJGH_RS41620	COG0671	phosphoesterase, PA-phosphatase related
SHJGH_RS41625	COG0671	phosphoesterase, PA-phosphatase related
SHJGH_RS41645	COG0305	Participates in initiation and elongation during chromosome replication
SHJGH_RS41650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SHJGH_RS41675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SHJGH_RS41710	COG4585	Histidine kinase
SHJGH_RS41715	COG2197	response regulator
SHJGH_RS41725	COG2272	Belongs to the type-B carboxylesterase lipase family
SHJGH_RS41740	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS41790	COG1028	Short-chain dehydrogenase reductase Sdr
SHJGH_RS41845	COG0475	glutathione-regulated potassium exporter activity
SHJGH_RS41860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SHJGH_RS41880	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SHJGH_RS41895	COG0477	Major facilitator Superfamily
SHJGH_RS41900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SHJGH_RS41935	COG1476	TRANSCRIPTIONal
SHJGH_RS41940	COG3903	Transcriptional regulator
SHJGH_RS41940	COG3629	intracellular signal transduction
SHJGH_RS41965	COG0702	epimerase
SHJGH_RS41990	COG0492	ferredoxin-NADP+ reductase activity
SHJGH_RS42035	COG2814	Major facilitator Superfamily
SHJGH_RS42040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SHJGH_RS42055	COG5285	phytanoyl-CoA dioxygenase
SHJGH_RS42080	COG2235	arginine
SHJGH_RS42085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SHJGH_RS42195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SHJGH_RS42220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SHJGH_RS42245	COG2801	Transposase and inactivated derivatives
SHJGH_RS42365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SHJGH_RS42375	COG2233	PERMEase
SHJGH_RS42385	COG0402	S-adenosylhomocysteine deaminase activity
SHJGH_RS42405	COG3547	Transposase (IS116 IS110 IS902 family)
SHJGH_RS42410	COG3547	Transposase (IS116 IS110 IS902 family)
SHJGH_RS42490	COG0517	IMP dehydrogenase activity
SHJGH_RS42490	COG0516	GMP reductase activity
SHJGH_RS42520	COG1063	alcohol dehydrogenase
SHJGH_RS42530	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJGH_RS42535	COG0022	dehydrogenase e1 component
SHJGH_RS42535	COG0508	dehydrogenase complex catalyzes the overall conversion of
SHJGH_RS42540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SHJGH_RS42545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SHJGH_RS42595	COG0569	domain protein
SHJGH_RS42600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SHJGH_RS42635	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SHJGH_RS42640	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SHJGH_RS42705	COG0574	Belongs to the PEP-utilizing enzyme family
SHJGH_RS42705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SHJGH_RS42715	COG0516	GMP reductase activity
SHJGH_RS42715	COG0517	IMP dehydrogenase activity
SHJGH_RS42900	COG0477	Major facilitator Superfamily
SHJGH_RS42925	COG3293	Transposase
SHJGH_RS43025	COG0583	DNA-binding transcription factor activity
SHJGH_RS43240	COG1902	pentaerythritol trinitrate reductase activity
SHJGH_RS43245	COG1902	pentaerythritol trinitrate reductase activity
SHJGH_RS43720	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SHJGH_RS43805	COG1216	Glycosyl transferase, family 2
SHJGH_RS43840	COG3387	PFAM Glycoside hydrolase 15-related
SHJGH_RS44275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SHJGH_RS44275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SHJGH_RS44390	COG1028	Short-chain dehydrogenase reductase Sdr