locus-tag	class	description
CP970_RS00010	COG0583	DNA-binding transcription factor activity
CP970_RS00020	COG1522	sequence-specific DNA binding
CP970_RS00035	COG0477	Major facilitator Superfamily
CP970_RS00080	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS00110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP970_RS00120	COG0494	nUDIX hydrolase
CP970_RS00150	COG1595	DNA-templated transcription, initiation
CP970_RS00155	COG3590	peptidase
CP970_RS00160	COG1802	Transcriptional regulator
CP970_RS00165	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS00175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP970_RS00180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP970_RS00195	COG0395	ABC-type sugar transport system, permease component
CP970_RS00205	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CP970_RS00205	COG3408	Glycogen debranching enzyme
CP970_RS00210	COG3291	Pkd domain containing protein
CP970_RS00240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP970_RS00275	COG0477	Major facilitator Superfamily
CP970_RS00325	COG3321	synthase
CP970_RS00325	COG0604	alcohol dehydrogenase
CP970_RS00330	COG0604	alcohol dehydrogenase
CP970_RS00330	COG3321	synthase
CP970_RS00340	COG2124	cytochrome p450
CP970_RS00355	COG2197	response regulator
CP970_RS00370	COG1132	(ABC) transporter
CP970_RS00380	COG1940	carbohydrate kinase activity
CP970_RS00380	COG1846	Transcriptional regulator
CP970_RS00390	COG1175	transmembrane transport
CP970_RS00395	COG0395	ABC-type sugar transport system, permease component
CP970_RS00400	COG2723	6-phospho-beta-galactosidase activity
CP970_RS00405	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CP970_RS00415	COG0738	Major facilitator superfamily
CP970_RS00425	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CP970_RS00430	COG1309	transcriptional regulator
CP970_RS00445	COG0435	Glutathione S-transferase
CP970_RS00460	COG1819	glycosyl
CP970_RS00465	COG0789	Transcriptional regulator
CP970_RS00490	COG2706	6-phosphogluconolactonase activity
CP970_RS00550	COG1131	(ABC) transporter
CP970_RS00560	COG0386	Belongs to the glutathione peroxidase family
CP970_RS00565	COG1686	Belongs to the peptidase S11 family
CP970_RS00570	COG0673	inositol 2-dehydrogenase activity
CP970_RS00595	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP970_RS00645	COG0181	hydroxymethylbilane synthase activity
CP970_RS00655	COG0542	response to heat
CP970_RS00680	COG0076	glutamate decarboxylase activity
CP970_RS00695	COG2814	Major facilitator Superfamily
CP970_RS00710	COG4948	Mandelate Racemase Muconate Lactonizing
CP970_RS00780	COG1846	Transcriptional regulator
CP970_RS00785	COG1733	regulation of RNA biosynthetic process
CP970_RS00815	COG2267	carboxylic ester hydrolase activity
CP970_RS00835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP970_RS00840	COG0154	amidase activity
CP970_RS00850	COG4221	oxidoreductase activity
CP970_RS00860	COG2070	2-Nitropropane dioxygenase
CP970_RS00885	COG0475	glutathione-regulated potassium exporter activity
CP970_RS00890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP970_RS00895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS00920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP970_RS00925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP970_RS00930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP970_RS00955	COG4221	oxidoreductase activity
CP970_RS00975	COG1131	(ABC) transporter
CP970_RS00985	COG4585	Histidine kinase
CP970_RS00990	COG2197	response regulator
CP970_RS01050	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP970_RS01055	COG1129	ABC transporter
CP970_RS01060	COG1846	Transcriptional regulator
CP970_RS01060	COG1940	carbohydrate kinase activity
CP970_RS01080	COG2318	DinB family
CP970_RS01190	COG2070	2-Nitropropane dioxygenase
CP970_RS01210	COG0154	amidase activity
CP970_RS01220	COG0515	serine threonine protein kinase
CP970_RS01235	COG1960	acyl-CoA dehydrogenase activity
CP970_RS01240	COG2318	DinB family
CP970_RS01250	COG3619	membrane
CP970_RS01275	COG0640	Transcriptional regulator
CP970_RS01310	COG1280	lysine exporter protein (LysE YggA)
CP970_RS01330	COG3629	intracellular signal transduction
CP970_RS01330	COG3903	Transcriptional regulator
CP970_RS01345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CP970_RS01350	COG4988	ABC transporter
CP970_RS01360	COG1271	oxidase subunit
CP970_RS01365	COG0583	DNA-binding transcription factor activity
CP970_RS01385	COG2192	nodulation
CP970_RS01425	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CP970_RS01430	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CP970_RS01435	COG1122	ATPase activity
CP970_RS01450	COG2066	Belongs to the glutaminase family
CP970_RS01470	COG0110	maltose O-acetyltransferase activity
CP970_RS01480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP970_RS01505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP970_RS01520	COG1024	Enoyl-CoA hydratase
CP970_RS01535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CP970_RS01550	COG3594	Acyltransferase
CP970_RS01585	COG0494	nUDIX hydrolase
CP970_RS01610	COG2175	clavaminate synthase activity
CP970_RS01635	COG2264	protein methyltransferase activity
CP970_RS01640	COG0483	inositol monophosphate 1-phosphatase activity
CP970_RS01660	COG0596	Alpha beta hydrolase
CP970_RS01685	COG2197	response regulator
CP970_RS01705	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS01775	COG1960	acyl-CoA dehydrogenase activity
CP970_RS01780	COG2171	N-acyltransferase activity
CP970_RS01790	COG3433	isochorismatase activity
CP970_RS01790	COG2226	methyltransferase
CP970_RS01790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP970_RS01830	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP970_RS01870	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS01890	COG0444	Belongs to the ABC transporter superfamily
CP970_RS01980	COG3800	Transcriptional regulator
CP970_RS01980	COG1396	sequence-specific DNA binding
CP970_RS01990	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP970_RS02015	COG3845	ABC transporter
CP970_RS02075	COG1280	lysine exporter protein (LysE YggA)
CP970_RS02095	COG1309	transcriptional regulator
CP970_RS02100	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS02125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CP970_RS02145	COG0583	DNA-binding transcription factor activity
CP970_RS02170	COG0604	alcohol dehydrogenase
CP970_RS02170	COG3321	synthase
CP970_RS02210	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP970_RS02215	COG2423	ornithine cyclodeaminase activity
CP970_RS02320	COG1309	transcriptional regulator
CP970_RS02355	COG0671	phosphoesterase, PA-phosphatase related
CP970_RS02360	COG0671	phosphoesterase, PA-phosphatase related
CP970_RS02385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS02400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS02415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CP970_RS02430	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP970_RS02455	COG2319	Wd-40 repeat
CP970_RS02455	COG4249	Peptidase C14 caspase catalytic subunit p20
CP970_RS02480	COG4106	trans-aconitate 2-methyltransferase activity
CP970_RS02535	COG1733	regulation of RNA biosynthetic process
CP970_RS02540	COG0702	epimerase
CP970_RS02560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP970_RS02565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS02570	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS02580	COG2205	protein histidine kinase activity
CP970_RS02585	COG0745	RESPONSE REGULATOR receiver
CP970_RS02590	COG0438	transferase activity, transferring glycosyl groups
CP970_RS02610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP970_RS02615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP970_RS02640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP970_RS02645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS02655	COG0825	malonyl-CoA metabolic process
CP970_RS02655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CP970_RS02660	COG0778	Nitroreductase
CP970_RS02685	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP970_RS02730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP970_RS02735	COG1609	Transcriptional regulator
CP970_RS02745	COG3858	chitin binding
CP970_RS02745	COG1388	LysM domain
CP970_RS02765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP970_RS02770	COG0121	glutamine amidotransferase
CP970_RS02775	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CP970_RS02780	COG2182	Extracellular solute-binding protein
CP970_RS02795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS02800	COG0577	efflux transmembrane transporter activity
CP970_RS02805	COG0577	efflux transmembrane transporter activity
CP970_RS02805	COG1136	(ABC) transporter
CP970_RS02820	COG0475	glutathione-regulated potassium exporter activity
CP970_RS02835	COG2124	cytochrome p450
CP970_RS02840	COG2124	cytochrome p450
CP970_RS02865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS02870	COG2205	protein histidine kinase activity
CP970_RS02875	COG0745	RESPONSE REGULATOR receiver
CP970_RS02880	COG1132	(ABC) transporter
CP970_RS02890	COG2267	carboxylic ester hydrolase activity
CP970_RS02895	COG1024	Enoyl-CoA hydratase
CP970_RS02900	COG1024	Enoyl-CoA hydratase
CP970_RS02905	COG3424	synthase
CP970_RS02915	COG0287	Prephenate dehydrogenase
CP970_RS02935	COG2207	Transcriptional regulator
CP970_RS02935	COG3708	Transcriptional regulator
CP970_RS02945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP970_RS02950	COG1053	succinate dehydrogenase
CP970_RS02960	COG0583	DNA-binding transcription factor activity
CP970_RS03005	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP970_RS03030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP970_RS03030	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP970_RS03040	COG0531	amino acid
CP970_RS03050	COG0395	ABC-type sugar transport system, permease component
CP970_RS03055	COG4209	transmembrane transport
CP970_RS03085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP970_RS03100	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CP970_RS03105	COG2197	response regulator
CP970_RS03125	COG3254	rhamnose metabolic process
CP970_RS03135	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS03140	COG4948	Mandelate Racemase Muconate Lactonizing
CP970_RS03150	COG1129	ABC transporter
CP970_RS03160	COG2186	Transcriptional regulator
CP970_RS03175	COG0395	ABC-type sugar transport system, permease component
CP970_RS03180	COG1175	transmembrane transport
CP970_RS03185	COG1653	transport
CP970_RS03190	COG1609	Transcriptional regulator
CP970_RS03205	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP970_RS03220	COG3537	Alpha-1,2-mannosidase
CP970_RS03225	COG3250	beta-galactosidase activity
CP970_RS03230	COG1609	Transcriptional regulator
CP970_RS03235	COG1879	ABC-type sugar transport system periplasmic component
CP970_RS03240	COG1129	ABC transporter
CP970_RS03245	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP970_RS03250	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP970_RS03255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP970_RS03260	COG0297	glycogen (starch) synthase activity
CP970_RS03280	COG3458	cephalosporin-C deacetylase activity
CP970_RS03315	COG3321	synthase
CP970_RS03315	COG0604	alcohol dehydrogenase
CP970_RS03340	COG0583	DNA-binding transcription factor activity
CP970_RS03365	COG1132	(ABC) transporter
CP970_RS03375	COG2807	transmembrane transport
CP970_RS03380	COG2186	Transcriptional regulator
CP970_RS03405	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS03485	COG0309	Hydrogenase expression formation protein (HypE)
CP970_RS03495	COG0516	GMP reductase activity
CP970_RS03495	COG0517	IMP dehydrogenase activity
CP970_RS03530	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP970_RS03535	COG2239	Acts as a magnesium transporter
CP970_RS03545	COG0298	carbon dioxide binding
CP970_RS03550	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CP970_RS03555	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CP970_RS03565	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CP970_RS03580	COG0531	amino acid
CP970_RS03690	COG0583	DNA-binding transcription factor activity
CP970_RS03695	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS03700	COG0183	Belongs to the thiolase family
CP970_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS03765	COG4585	Histidine kinase
CP970_RS03775	COG2197	response regulator
CP970_RS03790	COG0395	ABC-type sugar transport system, permease component
CP970_RS03795	COG1175	transmembrane transport
CP970_RS03830	COG1132	(ABC) transporter
CP970_RS03835	COG0668	transmembrane transport
CP970_RS03845	COG0321	lipoyl(octanoyl) transferase activity
CP970_RS03860	COG1335	isochorismatase
CP970_RS03880	COG2066	Belongs to the glutaminase family
CP970_RS03895	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP970_RS03915	COG1309	transcriptional regulator
CP970_RS03920	COG2409	Drug exporters of the RND superfamily
CP970_RS03925	COG0477	Major facilitator Superfamily
CP970_RS03965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS03970	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS03995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS04000	COG0475	glutathione-regulated potassium exporter activity
CP970_RS04015	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS04025	COG1324	tolerance protein
CP970_RS04045	COG3959	Transketolase, thiamine diphosphate binding domain
CP970_RS04050	COG3958	Transketolase
CP970_RS04065	COG2267	carboxylic ester hydrolase activity
CP970_RS04090	COG1116	anion transmembrane transporter activity
CP970_RS04100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP970_RS04110	COG0583	DNA-binding transcription factor activity
CP970_RS04115	COG0156	8-amino-7-oxononanoate synthase activity
CP970_RS04120	COG1063	alcohol dehydrogenase
CP970_RS04125	COG0673	inositol 2-dehydrogenase activity
CP970_RS04140	COG1609	Transcriptional regulator
CP970_RS04185	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS04235	COG0477	Major facilitator Superfamily
CP970_RS04240	COG2755	lipolytic protein G-D-S-L family
CP970_RS04250	COG2365	Tyrosine phosphatase family
CP970_RS04270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP970_RS04275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP970_RS04290	COG1657	PFAM Prenyltransferase squalene oxidase
CP970_RS04300	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP970_RS04310	COG1562	ergosterol biosynthetic process
CP970_RS04315	COG1134	teichoic acid transport
CP970_RS04370	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP970_RS04385	COG1024	Enoyl-CoA hydratase
CP970_RS04395	COG4977	sequence-specific DNA binding
CP970_RS04405	COG2183	response to ionizing radiation
CP970_RS04410	COG0488	(ABC) transporter
CP970_RS04420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP970_RS04430	COG2936	dipeptidyl-peptidase activity
CP970_RS04435	COG0308	aminopeptidase N
CP970_RS04445	COG2267	carboxylic ester hydrolase activity
CP970_RS04450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP970_RS04470	COG2197	response regulator
CP970_RS04480	COG1113	amino acid transport
CP970_RS04490	COG0789	Transcriptional regulator
CP970_RS04495	COG1024	Enoyl-CoA hydratase
CP970_RS04495	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP970_RS04500	COG0183	Belongs to the thiolase family
CP970_RS04505	COG1960	acyl-CoA dehydrogenase activity
CP970_RS04510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS04515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP970_RS04520	COG1683	Conserved Protein
CP970_RS04525	COG3268	Saccharopine dehydrogenase
CP970_RS04530	COG1515	deoxyribonuclease V activity
CP970_RS04535	COG1585	Membrane protein implicated in regulation of membrane protease activity
CP970_RS04540	COG2268	Band 7 protein
CP970_RS04560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP970_RS04575	COG4447	cellulose binding
CP970_RS04590	COG0488	(ABC) transporter
CP970_RS04595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP970_RS04600	COG1834	amidinotransferase
CP970_RS04615	COG1687	branched-chain amino acid
CP970_RS04625	COG1522	sequence-specific DNA binding
CP970_RS04655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS04660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CP970_RS04665	COG1116	anion transmembrane transporter activity
CP970_RS04670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP970_RS04720	COG1793	dna ligase
CP970_RS04720	COG3285	dna ligase
CP970_RS04725	COG1793	dna ligase
CP970_RS04755	COG3485	protocatechuate 3,4-dioxygenase
CP970_RS04760	COG3485	protocatechuate 3,4-dioxygenase
CP970_RS04770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS04785	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS04795	COG1024	Enoyl-CoA hydratase
CP970_RS04815	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP970_RS04815	COG1672	PFAM Archaeal ATPase
CP970_RS04820	COG0183	Belongs to the thiolase family
CP970_RS04825	COG1309	transcriptional regulator
CP970_RS04835	COG1960	acyl-CoA dehydrogenase activity
CP970_RS04845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CP970_RS04875	COG0525	valine-tRNA ligase activity
CP970_RS04880	COG3511	phospholipase C
CP970_RS04890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP970_RS04895	COG2318	DinB family
CP970_RS04900	COG1309	transcriptional regulator
CP970_RS04915	COG0456	acetyltransferase
CP970_RS04925	COG1486	melibiose metabolic process
CP970_RS04935	COG0477	Major facilitator Superfamily
CP970_RS04945	COG0657	acetylesterase activity
CP970_RS04955	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP970_RS04960	COG3246	L-lysine catabolic process to acetate
CP970_RS04985	COG1136	(ABC) transporter
CP970_RS04985	COG0577	efflux transmembrane transporter activity
CP970_RS05015	COG3629	intracellular signal transduction
CP970_RS05025	COG1404	Belongs to the peptidase S8 family
CP970_RS05055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP970_RS05060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP970_RS05070	COG0583	DNA-binding transcription factor activity
CP970_RS05085	COG3227	Zinc metalloprotease (Elastase)
CP970_RS05090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS05105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP970_RS05125	COG0151	Belongs to the GarS family
CP970_RS05130	COG2423	ornithine cyclodeaminase activity
CP970_RS05140	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS05155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP970_RS05180	COG1063	alcohol dehydrogenase
CP970_RS05185	COG1472	Belongs to the glycosyl hydrolase 3 family
CP970_RS05190	COG1309	transcriptional regulator
CP970_RS05205	COG2223	nitrite transmembrane transporter activity
CP970_RS05210	COG2207	Transcriptional regulator
CP970_RS05215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP970_RS05230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP970_RS05235	COG3938	Belongs to the proline racemase family
CP970_RS05240	COG1802	Transcriptional regulator
CP970_RS05270	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS05280	COG0045	succinate-CoA ligase (ADP-forming) activity
CP970_RS05290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP970_RS05300	COG2223	nitrite transmembrane transporter activity
CP970_RS05325	COG0084	hydrolase, TatD family'
CP970_RS05340	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CP970_RS05365	COG0673	inositol 2-dehydrogenase activity
CP970_RS05370	COG1879	ABC-type sugar transport system periplasmic component
CP970_RS05375	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP970_RS05380	COG1129	ABC transporter
CP970_RS05385	COG1940	carbohydrate kinase activity
CP970_RS05400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP970_RS05410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP970_RS05415	COG3383	formate dehydrogenase (NAD+) activity
CP970_RS05430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP970_RS05435	COG1846	Transcriptional regulator
CP970_RS05515	COG0477	Major facilitator Superfamily
CP970_RS05550	COG3469	chitinase activity
CP970_RS05570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CP970_RS05620	COG2226	methyltransferase
CP970_RS05625	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP970_RS05645	COG1140	nitrate reductase beta subunit
CP970_RS05660	COG0443	Heat shock 70 kDa protein
CP970_RS05675	COG0531	amino acid
CP970_RS05695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP970_RS05700	COG1518	maintenance of DNA repeat elements
CP970_RS05715	COG1857	crispr-associated protein
CP970_RS05775	COG1484	DNA-dependent DNA replication
CP970_RS05815	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS05830	COG0739	heme binding
CP970_RS05830	COG0741	lytic transglycosylase activity
CP970_RS05830	COG1196	nuclear chromosome segregation
CP970_RS06090	COG0515	serine threonine protein kinase
CP970_RS06090	COG2815	serine threonine protein kinase
CP970_RS06190	COG1191	sigma factor activity
CP970_RS06195	COG0517	IMP dehydrogenase activity
CP970_RS06210	COG0488	(ABC) transporter
CP970_RS06215	COG1597	lipid kinase activity
CP970_RS06265	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP970_RS06270	COG0402	S-adenosylhomocysteine deaminase activity
CP970_RS06280	COG0010	Belongs to the arginase family
CP970_RS06305	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP970_RS06315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP970_RS06320	COG2362	D-Aminopeptidase
CP970_RS06330	COG2957	Belongs to the agmatine deiminase family
CP970_RS06345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS06360	COG2957	Belongs to the agmatine deiminase family
CP970_RS06365	COG0804	urea catabolic process
CP970_RS06370	COG0832	Belongs to the urease beta subunit family
CP970_RS06370	COG0831	urea catabolic process
CP970_RS06400	COG3467	pyridoxamine 5'-phosphate
CP970_RS06415	COG2249	NAD(P)H dehydrogenase (quinone) activity
CP970_RS06440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS06445	COG1120	ATPase activity
CP970_RS06460	COG1414	Transcriptional regulator
CP970_RS06490	COG4214	carbohydrate transport
CP970_RS06500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP970_RS06510	COG2226	methyltransferase
CP970_RS06515	COG2172	sigma factor antagonist activity
CP970_RS06515	COG1366	Belongs to the anti-sigma-factor antagonist family
CP970_RS06515	COG2208	phosphoserine phosphatase activity
CP970_RS06595	COG0673	inositol 2-dehydrogenase activity
CP970_RS06635	COG1162	GTPase activity
CP970_RS06650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP970_RS06660	COG0604	alcohol dehydrogenase
CP970_RS06665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP970_RS06665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP970_RS06670	COG2301	Belongs to the HpcH HpaI aldolase family
CP970_RS06680	COG1960	acyl-CoA dehydrogenase activity
CP970_RS06685	COG0688	phosphatidylethanolamine metabolic process
CP970_RS06695	COG1063	alcohol dehydrogenase
CP970_RS06720	COG1929	Belongs to the glycerate kinase type-1 family
CP970_RS06725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP970_RS06755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP970_RS06770	COG0483	inositol monophosphate 1-phosphatase activity
CP970_RS06780	COG0095	Lipoate-protein ligase
CP970_RS06790	COG2197	response regulator
CP970_RS06800	COG2226	methyltransferase
CP970_RS06820	COG3629	intracellular signal transduction
CP970_RS06820	COG3903	Transcriptional regulator
CP970_RS06830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP970_RS06835	COG2267	carboxylic ester hydrolase activity
CP970_RS06845	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CP970_RS06850	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS06880	COG2050	protein possibly involved in aromatic compounds catabolism
CP970_RS06900	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP970_RS06930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS06940	COG0477	Major facilitator Superfamily
CP970_RS06945	COG2267	carboxylic ester hydrolase activity
CP970_RS06975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS06985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP970_RS06995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP970_RS07010	COG0657	acetylesterase activity
CP970_RS07035	COG0736	holo-[acyl-carrier-protein] synthase activity
CP970_RS07050	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP970_RS07055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP970_RS07090	COG0405	Gamma-glutamyltransferase
CP970_RS07100	COG1376	ErfK ybiS ycfS ynhG family protein
CP970_RS07110	COG0765	amino acid transport
CP970_RS07115	COG0765	amino acid transport
CP970_RS07120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP970_RS07125	COG1126	abc transporter atp-binding protein
CP970_RS07145	COG0069	glutamate synthase activity
CP970_RS07155	COG1131	(ABC) transporter
CP970_RS07160	COG4585	Histidine kinase
CP970_RS07165	COG2197	response regulator
CP970_RS07190	COG2329	Antibiotic biosynthesis monooxygenase
CP970_RS07195	COG0662	Cupin 2, conserved barrel domain protein
CP970_RS07205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS07215	COG2867	negative regulation of translational initiation
CP970_RS07220	COG0511	ligase activity, forming carbon-carbon bonds
CP970_RS07230	COG4585	Histidine kinase
CP970_RS07235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CP970_RS07235	COG0825	malonyl-CoA metabolic process
CP970_RS07240	COG0439	Biotin carboxylase
CP970_RS07250	COG0475	glutathione-regulated potassium exporter activity
CP970_RS07260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP970_RS07275	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP970_RS07280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS07340	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS07375	COG2345	Transcriptional regulator
CP970_RS07395	COG3033	Beta-eliminating lyase
CP970_RS07425	COG1302	Protein conserved in bacteria
CP970_RS07570	COG1309	transcriptional regulator
CP970_RS07615	COG1846	Transcriptional regulator
CP970_RS07645	COG0798	PFAM Bile acid sodium symporter
CP970_RS07655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP970_RS07675	COG0300	oxidoreductase activity
CP970_RS07680	COG1408	metallophosphoesterase
CP970_RS07705	COG2197	response regulator
CP970_RS07720	COG2310	stress, protein
CP970_RS07725	COG2423	ornithine cyclodeaminase activity
CP970_RS07745	COG1940	carbohydrate kinase activity
CP970_RS07755	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP970_RS07770	COG2188	Transcriptional regulator
CP970_RS07775	COG0673	inositol 2-dehydrogenase activity
CP970_RS07785	COG2197	response regulator
CP970_RS07815	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS07820	COG4266	Belongs to the allantoicase family
CP970_RS07825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP970_RS07830	COG1414	Transcriptional regulator
CP970_RS07845	COG0577	efflux transmembrane transporter activity
CP970_RS07850	COG4585	Histidine kinase
CP970_RS07865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP970_RS07880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP970_RS07920	COG4585	Histidine kinase
CP970_RS07925	COG1131	(ABC) transporter
CP970_RS07940	COG2205	protein histidine kinase activity
CP970_RS07945	COG0745	RESPONSE REGULATOR receiver
CP970_RS07950	COG2205	protein histidine kinase activity
CP970_RS07960	COG1136	(ABC) transporter
CP970_RS07965	COG1136	(ABC) transporter
CP970_RS07975	COG0745	RESPONSE REGULATOR receiver
CP970_RS08000	COG0671	phosphoesterase, PA-phosphatase related
CP970_RS08040	COG4989	oxidoreductase activity
CP970_RS08050	COG0436	Aminotransferase
CP970_RS08075	COG0588	phosphoglycerate mutase activity
CP970_RS08095	COG2356	endonuclease I
CP970_RS08105	COG0667	Aldo Keto reductase
CP970_RS08200	COG0477	Major facilitator Superfamily
CP970_RS08205	COG2133	pyrroloquinoline quinone binding
CP970_RS08205	COG5183	chlorophyll binding
CP970_RS08220	COG0477	Major facilitator Superfamily
CP970_RS08260	COG2233	PERMEase
CP970_RS08270	COG2233	PERMEase
CP970_RS08280	COG2233	PERMEase
CP970_RS08290	COG2351	hydroxyisourate hydrolase activity
CP970_RS08310	COG3622	Belongs to the hyi family
CP970_RS08315	COG2084	Dehydrogenase
CP970_RS08320	COG0753	catalase activity
CP970_RS08330	COG3960	tartronate-semialdehyde synthase activity
CP970_RS08335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP970_RS08335	COG0515	serine threonine protein kinase
CP970_RS08345	COG2814	Major facilitator Superfamily
CP970_RS08355	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS08375	COG1595	DNA-templated transcription, initiation
CP970_RS08405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP970_RS08420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP970_RS08420	COG0515	serine threonine protein kinase
CP970_RS08425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP970_RS08430	COG2197	response regulator
CP970_RS08440	COG0583	DNA-binding transcription factor activity
CP970_RS08450	COG0598	Magnesium transport protein CorA
CP970_RS08465	COG1231	oxidoreductase activity
CP970_RS08515	COG0077	Prephenate dehydratase
CP970_RS08545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS08590	COG0477	Major facilitator Superfamily
CP970_RS08605	COG0463	Glycosyl transferase, family 2
CP970_RS08650	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS08670	COG0667	Aldo Keto reductase
CP970_RS08685	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS08695	COG1316	TRANSCRIPTIONal
CP970_RS08710	COG1335	isochorismatase
CP970_RS08720	COG3594	Acyltransferase
CP970_RS08765	COG0577	efflux transmembrane transporter activity
CP970_RS08765	COG1136	(ABC) transporter
CP970_RS08770	COG1136	(ABC) transporter
CP970_RS08770	COG0577	efflux transmembrane transporter activity
CP970_RS08775	COG2205	protein histidine kinase activity
CP970_RS08780	COG0745	RESPONSE REGULATOR receiver
CP970_RS08830	COG0640	Transcriptional regulator
CP970_RS08855	COG3021	interspecies interaction between organisms
CP970_RS08885	COG0076	glutamate decarboxylase activity
CP970_RS08935	COG2252	PERMEase
CP970_RS08940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP970_RS08955	COG3835	regulator
CP970_RS08965	COG1802	Transcriptional regulator
CP970_RS08990	COG0028	Belongs to the TPP enzyme family
CP970_RS09000	COG1404	Belongs to the peptidase S8 family
CP970_RS09030	COG1162	GTPase activity
CP970_RS09060	COG2124	cytochrome p450
CP970_RS09130	COG0494	nUDIX hydrolase
CP970_RS09160	COG1960	acyl-CoA dehydrogenase activity
CP970_RS09175	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP970_RS09185	COG0175	sulfate reduction
CP970_RS09190	COG0529	Catalyzes the synthesis of activated sulfate
CP970_RS09210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CP970_RS09215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP970_RS09235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP970_RS09290	COG0596	Alpha beta hydrolase
CP970_RS09295	COG2409	Drug exporters of the RND superfamily
CP970_RS09305	COG2197	response regulator
CP970_RS09385	COG0667	Aldo Keto reductase
CP970_RS09395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP970_RS09435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP970_RS09440	COG0443	Heat shock 70 kDa protein
CP970_RS09445	COG0443	Heat shock 70 kDa protein
CP970_RS09500	COG1609	Transcriptional regulator
CP970_RS09505	COG1129	ABC transporter
CP970_RS09515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP970_RS09520	COG1869	D-ribose catabolic process
CP970_RS09525	COG4935	Belongs to the peptidase S8 family
CP970_RS09525	COG2234	aminopeptidase activity
CP970_RS09550	COG1024	Enoyl-CoA hydratase
CP970_RS09555	COG1024	Enoyl-CoA hydratase
CP970_RS09560	COG3424	synthase
CP970_RS09565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS09570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS09570	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CP970_RS09575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS09605	COG1132	(ABC) transporter
CP970_RS09610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP970_RS09615	COG1473	amidohydrolase
CP970_RS09630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS09635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS09665	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS09670	COG2197	response regulator
CP970_RS09675	COG4585	Histidine kinase
CP970_RS09680	COG3903	Transcriptional regulator
CP970_RS09680	COG3629	intracellular signal transduction
CP970_RS09685	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS09690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP970_RS09695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP970_RS09700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS09715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP970_RS09720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP970_RS09745	COG2326	polyphosphate kinase activity
CP970_RS09750	COG0604	alcohol dehydrogenase
CP970_RS09770	COG1733	regulation of RNA biosynthetic process
CP970_RS09780	COG3568	Endonuclease Exonuclease Phosphatase
CP970_RS09810	COG0251	oxidation-reduction process
CP970_RS09820	COG2264	protein methyltransferase activity
CP970_RS09830	COG2267	carboxylic ester hydrolase activity
CP970_RS09850	COG1121	(ABC) transporter
CP970_RS09865	COG3220	belongs to the UPF0276 family
CP970_RS09895	COG3253	May function as heme-dependent peroxidase
CP970_RS09900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP970_RS09910	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP970_RS09915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP970_RS09930	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CP970_RS09935	COG0183	Belongs to the thiolase family
CP970_RS09940	COG1024	Enoyl-CoA hydratase
CP970_RS09940	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP970_RS09960	COG0531	amino acid
CP970_RS09965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP970_RS09970	COG4214	carbohydrate transport
CP970_RS09980	COG4213	ABC transporter substrate-binding protein
CP970_RS09985	COG1940	carbohydrate kinase activity
CP970_RS09990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP970_RS09990	COG0515	serine threonine protein kinase
CP970_RS10005	COG0395	ABC-type sugar transport system, permease component
CP970_RS10020	COG0395	ABC-type sugar transport system, permease component
CP970_RS10025	COG1175	transmembrane transport
CP970_RS10060	COG0702	epimerase
CP970_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS10130	COG2814	Major facilitator Superfamily
CP970_RS10145	COG0154	amidase activity
CP970_RS10160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP970_RS10185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP970_RS10220	COG1024	Enoyl-CoA hydratase
CP970_RS10230	COG0531	amino acid
CP970_RS10235	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP970_RS10240	COG2235	arginine
CP970_RS10245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP970_RS10280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS10365	COG1799	cell septum assembly
CP970_RS10370	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CP970_RS10375	COG2382	esterase
CP970_RS10380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS10385	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS10390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP970_RS10495	COG1846	Transcriptional regulator
CP970_RS10500	COG1764	response to oxidative stress
CP970_RS10520	COG2080	2 iron, 2 sulfur cluster binding
CP970_RS10520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP970_RS10550	COG0667	Aldo Keto reductase
CP970_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS10585	COG4221	oxidoreductase activity
CP970_RS10605	COG2197	response regulator
CP970_RS10615	COG3903	Transcriptional regulator
CP970_RS10615	COG3629	intracellular signal transduction
CP970_RS10625	COG1960	acyl-CoA dehydrogenase activity
CP970_RS10630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP970_RS10660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP970_RS10665	COG0531	amino acid
CP970_RS10690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP970_RS10695	COG4865	methylaspartate mutase activity
CP970_RS10720	COG3629	intracellular signal transduction
CP970_RS10720	COG3903	Transcriptional regulator
CP970_RS10725	COG5006	permease, DMT superfamily
CP970_RS10735	COG0442	prolyl-tRNA aminoacylation
CP970_RS10755	COG0017	Asparaginyl-tRNA synthetase
CP970_RS10765	COG0569	domain protein
CP970_RS10795	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP970_RS10795	COG1136	(ABC) transporter
CP970_RS10805	COG0577	efflux transmembrane transporter activity
CP970_RS10805	COG1136	(ABC) transporter
CP970_RS10825	COG0756	dUTP diphosphatase activity
CP970_RS10850	COG2205	protein histidine kinase activity
CP970_RS10855	COG0745	RESPONSE REGULATOR receiver
CP970_RS10865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP970_RS10925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP970_RS10930	COG1802	Transcriptional regulator
CP970_RS10945	COG0612	Peptidase, M16
CP970_RS10950	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP970_RS10980	COG0372	Belongs to the citrate synthase family
CP970_RS10995	COG3290	protein histidine kinase activity
CP970_RS11000	COG4565	transcriptional regulatory protein
CP970_RS11005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP970_RS11015	COG2197	response regulator
CP970_RS11030	COG0187	DNA topoisomerase II activity
CP970_RS11100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP970_RS11105	COG2186	Transcriptional regulator
CP970_RS11145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP970_RS11170	COG0588	phosphoglycerate mutase activity
CP970_RS11175	COG0488	(ABC) transporter
CP970_RS11200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP970_RS11205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP970_RS11210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP970_RS11250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP970_RS11260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP970_RS11265	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP970_RS11275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP970_RS11295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP970_RS11305	COG2205	protein histidine kinase activity
CP970_RS11310	COG0745	RESPONSE REGULATOR receiver
CP970_RS11315	COG1126	abc transporter atp-binding protein
CP970_RS11320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP970_RS11325	COG0765	amino acid transport
CP970_RS11330	COG0765	amino acid transport
CP970_RS11345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP970_RS11365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP970_RS11375	COG1595	DNA-templated transcription, initiation
CP970_RS11385	COG0628	permease
CP970_RS11435	COG1201	RNA secondary structure unwinding
CP970_RS11440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP970_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS11455	COG0783	Belongs to the Dps family
CP970_RS11460	COG1396	sequence-specific DNA binding
CP970_RS11465	COG1546	Belongs to the CinA family
CP970_RS11465	COG1058	Belongs to the CinA family
CP970_RS11475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP970_RS11485	COG1674	ftsk spoiiie
CP970_RS11495	COG2205	protein histidine kinase activity
CP970_RS11495	COG3437	response regulator, receiver
CP970_RS11495	COG3850	Histidine kinase
CP970_RS11495	COG4999	Histidine kinase
CP970_RS11505	COG2208	phosphoserine phosphatase activity
CP970_RS11505	COG2770	Histidine kinase
CP970_RS11540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP970_RS11545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP970_RS11550	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP970_RS11570	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP970_RS11575	COG0612	Peptidase, M16
CP970_RS11580	COG1185	polyribonucleotide nucleotidyltransferase activity
CP970_RS11585	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP970_RS11635	COG0455	bacterial-type flagellum organization
CP970_RS11645	COG4166	transmembrane transport
CP970_RS11650	COG0601	transmembrane transport
CP970_RS11655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS11665	COG4608	Belongs to the ABC transporter superfamily
CP970_RS11680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP970_RS11685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP970_RS11695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP970_RS11710	COG0779	Required for maturation of 30S ribosomal subunits
CP970_RS11720	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CP970_RS11725	COG0442	prolyl-tRNA aminoacylation
CP970_RS11740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP970_RS11745	COG0750	zinc metalloprotease
CP970_RS11750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP970_RS11755	COG0653	protein targeting
CP970_RS11775	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS11780	COG2508	Transcriptional regulator
CP970_RS11780	COG2508	Transcriptional regulator
CP970_RS11810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP970_RS11815	COG1177	transmembrane transport
CP970_RS11820	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP970_RS11825	COG3842	ATPase activity
CP970_RS11835	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS11850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP970_RS11860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP970_RS11870	COG0596	Alpha beta hydrolase
CP970_RS11890	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS11900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP970_RS11905	COG1136	(ABC) transporter
CP970_RS11930	COG4585	Histidine kinase
CP970_RS11935	COG2197	response regulator
CP970_RS11945	COG3842	ATPase activity
CP970_RS11960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP970_RS11970	COG0575	Belongs to the CDS family
CP970_RS11975	COG0233	cytoplasmic translational termination
CP970_RS11980	COG0528	UMP kinase activity
CP970_RS11985	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP970_RS11990	COG0052	Belongs to the universal ribosomal protein uS2 family
CP970_RS11995	COG4942	peptidase
CP970_RS12005	COG1191	sigma factor activity
CP970_RS12020	COG0792	nuclease activity
CP970_RS12030	COG1051	belongs to the nudix hydrolase family
CP970_RS12040	COG0681	Belongs to the peptidase S26 family
CP970_RS12045	COG0681	Belongs to the peptidase S26 family
CP970_RS12055	COG0335	large ribosomal subunit rRNA binding
CP970_RS12060	COG0336	Belongs to the RNA methyltransferase TrmD family
CP970_RS12065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP970_RS12070	COG1837	Belongs to the UPF0109 family
CP970_RS12075	COG0228	four-way junction DNA binding
CP970_RS12085	COG0442	prolyl-tRNA aminoacylation
CP970_RS12095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP970_RS12135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CP970_RS12145	COG0477	Major facilitator Superfamily
CP970_RS12150	COG1196	nuclear chromosome segregation
CP970_RS12160	COG1254	Belongs to the acylphosphatase family
CP970_RS12165	COG2340	Cysteine-rich secretory protein family
CP970_RS12170	COG1733	regulation of RNA biosynthetic process
CP970_RS12175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP970_RS12180	COG0571	ribonuclease III activity
CP970_RS12185	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP970_RS12200	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP970_RS12205	COG0742	ribosomal rna small subunit methyltransferase
CP970_RS12215	COG1461	Dihydroxyacetone kinase
CP970_RS12220	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP970_RS12235	COG0351	phosphomethylpyrimidine kinase
CP970_RS12255	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP970_RS12260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP970_RS12270	COG1920	GTP binding
CP970_RS12280	COG0776	regulation of translation
CP970_RS12290	COG0066	3-isopropylmalate dehydratase activity
CP970_RS12295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP970_RS12300	COG1414	Transcriptional regulator
CP970_RS12345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP970_RS12350	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP970_RS12360	COG5002	protein histidine kinase activity
CP970_RS12365	COG2018	Roadblock/LC7 domain
CP970_RS12385	COG2018	Roadblock/LC7 domain
CP970_RS12410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP970_RS12460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP970_RS12485	COG2957	Belongs to the agmatine deiminase family
CP970_RS12490	COG0804	urea catabolic process
CP970_RS12495	COG0832	Belongs to the urease beta subunit family
CP970_RS12495	COG0831	urea catabolic process
CP970_RS12505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP970_RS12510	COG0473	3-isopropylmalate dehydrogenase activity
CP970_RS12525	COG0583	DNA-binding transcription factor activity
CP970_RS12530	COG2130	NADP-dependent
CP970_RS12560	COG1902	pentaerythritol trinitrate reductase activity
CP970_RS12565	COG0789	Transcriptional regulator
CP970_RS12580	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS12585	COG0506	proline dehydrogenase activity
CP970_RS12600	COG0587	DNA-directed DNA polymerase activity
CP970_RS12615	COG0477	Major facilitator Superfamily
CP970_RS12620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP970_RS12625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP970_RS12630	COG0440	acetolactate synthase activity
CP970_RS12650	COG0667	Aldo Keto reductase
CP970_RS12655	COG2133	pyrroloquinoline quinone binding
CP970_RS12665	COG2197	response regulator
CP970_RS12685	COG2409	Drug exporters of the RND superfamily
CP970_RS12700	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP970_RS12710	COG0154	amidase activity
CP970_RS12715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP970_RS12730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP970_RS12740	COG4221	oxidoreductase activity
CP970_RS12765	COG0482	sulfurtransferase activity
CP970_RS12795	COG2378	regulation of single-species biofilm formation
CP970_RS12805	COG2860	membrane
CP970_RS12815	COG0308	aminopeptidase N
CP970_RS12820	COG4608	Belongs to the ABC transporter superfamily
CP970_RS12825	COG0444	Belongs to the ABC transporter superfamily
CP970_RS12840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS12860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP970_RS12865	COG0509	glycine decarboxylation via glycine cleavage system
CP970_RS12870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP970_RS12875	COG1760	l-serine dehydratase
CP970_RS12890	COG0326	Molecular chaperone. Has ATPase activity
CP970_RS12950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP970_RS12955	COG3757	hydrolase, family 25
CP970_RS12955	COG3409	Peptidoglycan-binding domain 1 protein
CP970_RS12975	COG1024	Enoyl-CoA hydratase
CP970_RS12995	COG0583	DNA-binding transcription factor activity
CP970_RS13005	COG2197	response regulator
CP970_RS13010	COG4585	Histidine kinase
CP970_RS13020	COG1131	(ABC) transporter
CP970_RS13025	COG1132	(ABC) transporter
CP970_RS13030	COG1132	(ABC) transporter
CP970_RS13050	COG0058	SHG alpha-glucan phosphorylase activity
CP970_RS13065	COG0366	Alpha amylase catalytic
CP970_RS13080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP970_RS13090	COG0492	ferredoxin-NADP+ reductase activity
CP970_RS13090	COG3118	belongs to the thioredoxin family
CP970_RS13105	COG1140	nitrate reductase beta subunit
CP970_RS13110	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CP970_RS13125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP970_RS13165	COG0477	Major facilitator Superfamily
CP970_RS13175	COG1301	dicarboxylic acid transport
CP970_RS13180	COG3290	protein histidine kinase activity
CP970_RS13185	COG4565	transcriptional regulatory protein
CP970_RS13200	COG0395	ABC-type sugar transport system, permease component
CP970_RS13220	COG0205	6-phosphofructokinase activity
CP970_RS13225	COG0857	belongs to the CobB CobQ family
CP970_RS13225	COG0280	phosphate acetyltransferase
CP970_RS13230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP970_RS13270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP970_RS13275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP970_RS13280	COG0745	RESPONSE REGULATOR receiver
CP970_RS13295	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP970_RS13295	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP970_RS13385	COG0745	RESPONSE REGULATOR receiver
CP970_RS13400	COG0183	Belongs to the thiolase family
CP970_RS13460	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP970_RS13475	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP970_RS13480	COG1309	transcriptional regulator
CP970_RS13505	COG4585	Histidine kinase
CP970_RS13510	COG2197	response regulator
CP970_RS13525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP970_RS13530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP970_RS13535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP970_RS13540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP970_RS13545	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP970_RS13550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP970_RS13555	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP970_RS13580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP970_RS13590	COG2890	protein-(glutamine-N5) methyltransferase activity
CP970_RS13595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP970_RS13600	COG0254	rRNA binding
CP970_RS13605	COG1316	TRANSCRIPTIONal
CP970_RS13615	COG0083	homoserine kinase activity
CP970_RS13620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP970_RS13625	COG0460	homoserine dehydrogenase
CP970_RS13630	COG0019	diaminopimelate decarboxylase activity
CP970_RS13635	COG0018	arginyl-trna synthetase
CP970_RS13675	COG0556	nucleotide-excision repair
CP970_RS13695	COG2197	response regulator
CP970_RS13705	COG1222	aaa ATPase
CP970_RS13720	COG3629	intracellular signal transduction
CP970_RS13720	COG3903	Transcriptional regulator
CP970_RS13795	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP970_RS13800	COG1793	dna ligase
CP970_RS13800	COG3285	dna ligase
CP970_RS13835	COG2205	protein histidine kinase activity
CP970_RS13845	COG0772	Belongs to the SEDS family
CP970_RS13850	COG0768	penicillin binding
CP970_RS13900	COG5002	protein histidine kinase activity
CP970_RS13930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP970_RS13935	COG1595	DNA-templated transcription, initiation
CP970_RS13955	COG0745	RESPONSE REGULATOR receiver
CP970_RS13960	COG2205	protein histidine kinase activity
CP970_RS13965	COG0567	Dehydrogenase, E1 component
CP970_RS13965	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP970_RS14010	COG0604	alcohol dehydrogenase
CP970_RS14025	COG0765	amino acid transport
CP970_RS14035	COG4106	trans-aconitate 2-methyltransferase activity
CP970_RS14065	COG2197	response regulator
CP970_RS14085	COG1595	DNA-templated transcription, initiation
CP970_RS14095	COG1011	Hydrolase
CP970_RS14140	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS14145	COG0142	geranyltranstransferase activity
CP970_RS14150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP970_RS14155	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP970_RS14170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CP970_RS14185	COG2172	sigma factor antagonist activity
CP970_RS14200	COG1597	lipid kinase activity
CP970_RS14215	COG1309	transcriptional regulator
CP970_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS14225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP970_RS14230	COG0363	glucosamine-6-phosphate deaminase activity
CP970_RS14235	COG1472	Belongs to the glycosyl hydrolase 3 family
CP970_RS14240	COG0395	ABC-type sugar transport system, permease component
CP970_RS14245	COG1175	transmembrane transport
CP970_RS14250	COG2182	Extracellular solute-binding protein
CP970_RS14255	COG2188	Transcriptional regulator
CP970_RS14260	COG1966	Carbon starvation protein
CP970_RS14290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP970_RS14295	COG2124	cytochrome p450
CP970_RS14305	COG0242	peptide deformylase activity
CP970_RS14320	COG2199	diguanylate cyclase activity
CP970_RS14320	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP970_RS14325	COG5662	AntiSigma factor
CP970_RS14330	COG1595	DNA-templated transcription, initiation
CP970_RS14340	COG2135	peptidase activity
CP970_RS14350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP970_RS14360	COG2076	Multidrug Resistance protein
CP970_RS14370	COG0483	inositol monophosphate 1-phosphatase activity
CP970_RS14380	COG0753	catalase activity
CP970_RS14420	COG1615	UPF0182 protein
CP970_RS14430	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP970_RS14480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP970_RS14520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP970_RS14525	COG0210	DNA helicase
CP970_RS14560	COG1140	nitrate reductase beta subunit
CP970_RS14580	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP970_RS14630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS14635	COG0747	negative chemotaxis
CP970_RS14675	COG0513	Belongs to the DEAD box helicase family
CP970_RS14695	COG1432	Conserved Protein
CP970_RS14700	COG2095	MarC family integral membrane protein
CP970_RS14715	COG2814	Major facilitator Superfamily
CP970_RS14725	COG0598	Magnesium transport protein CorA
CP970_RS14760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP970_RS14765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP970_RS14775	COG1595	DNA-templated transcription, initiation
CP970_RS14795	COG1024	Enoyl-CoA hydratase
CP970_RS14800	COG2818	Glycosylase
CP970_RS14810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP970_RS14815	COG1611	Belongs to the LOG family
CP970_RS14820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP970_RS14860	COG2197	response regulator
CP970_RS14865	COG4585	Histidine kinase
CP970_RS14875	COG1131	(ABC) transporter
CP970_RS14890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP970_RS14905	COG4608	Belongs to the ABC transporter superfamily
CP970_RS14910	COG0444	Belongs to the ABC transporter superfamily
CP970_RS14915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS14920	COG0601	transmembrane transport
CP970_RS14930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS14935	COG0747	negative chemotaxis
CP970_RS14945	COG0444	Belongs to the ABC transporter superfamily
CP970_RS14950	COG4608	Belongs to the ABC transporter superfamily
CP970_RS14960	COG1595	DNA-templated transcription, initiation
CP970_RS14970	COG4608	Belongs to the ABC transporter superfamily
CP970_RS14975	COG0444	Belongs to the ABC transporter superfamily
CP970_RS14980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS14985	COG0601	transmembrane transport
CP970_RS14995	COG1217	gtp-binding protein TYPA
CP970_RS15015	COG1053	succinate dehydrogenase
CP970_RS15020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP970_RS15055	COG1175	transmembrane transport
CP970_RS15060	COG0395	ABC-type sugar transport system, permease component
CP970_RS15080	COG1842	Phage shock protein A
CP970_RS15125	COG1595	DNA-templated transcription, initiation
CP970_RS15160	COG0515	serine threonine protein kinase
CP970_RS15160	COG2815	serine threonine protein kinase
CP970_RS15180	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CP970_RS15205	COG0012	GTP binding
CP970_RS15220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP970_RS15230	COG1570	exodeoxyribonuclease VII activity
CP970_RS15235	COG1722	exodeoxyribonuclease VII activity
CP970_RS15240	COG0778	Nitroreductase
CP970_RS15265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP970_RS15265	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP970_RS15275	COG0114	fumarate hydratase activity
CP970_RS15300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP970_RS15310	COG1136	(ABC) transporter
CP970_RS15325	COG0450	alkyl hydroperoxide reductase
CP970_RS15330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS15345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP970_RS15350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP970_RS15355	COG0667	Aldo Keto reductase
CP970_RS15370	COG1733	regulation of RNA biosynthetic process
CP970_RS15385	COG2885	chlorophyll binding
CP970_RS15425	COG2894	cell division
CP970_RS15460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP970_RS15475	COG1309	transcriptional regulator
CP970_RS15490	COG2610	gluconate transmembrane transporter activity
CP970_RS15495	COG0251	oxidation-reduction process
CP970_RS15500	COG1414	Transcriptional regulator
CP970_RS15515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP970_RS15535	COG1278	Cold shock
CP970_RS15550	COG0436	Aminotransferase
CP970_RS15565	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP970_RS15575	COG0477	Major facilitator Superfamily
CP970_RS15580	COG1309	transcriptional regulator
CP970_RS15590	COG1331	Highly conserved protein containing a thioredoxin domain
CP970_RS15600	COG1331	Highly conserved protein containing a thioredoxin domain
CP970_RS15610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP970_RS15630	COG1309	transcriptional regulator
CP970_RS15635	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS15640	COG2318	DinB family
CP970_RS15660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP970_RS15670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP970_RS15685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP970_RS15690	COG2255	four-way junction helicase activity
CP970_RS15695	COG1595	DNA-templated transcription, initiation
CP970_RS15715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP970_RS15725	COG0740	serine-type endopeptidase activity
CP970_RS15730	COG0740	serine-type endopeptidase activity
CP970_RS15745	COG1064	alcohol dehydrogenase
CP970_RS15755	COG0596	Alpha beta hydrolase
CP970_RS15755	COG2945	thiolester hydrolase activity
CP970_RS15765	COG1733	regulation of RNA biosynthetic process
CP970_RS15775	COG1404	Belongs to the peptidase S8 family
CP970_RS15780	COG1136	(ABC) transporter
CP970_RS15785	COG1376	ErfK ybiS ycfS ynhG family protein
CP970_RS15820	COG0477	Major facilitator Superfamily
CP970_RS15830	COG0531	amino acid
CP970_RS15840	COG2986	histidine ammonia-lyase
CP970_RS15850	COG1024	Enoyl-CoA hydratase
CP970_RS15855	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP970_RS15865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP970_RS15875	COG0424	maF-like protein
CP970_RS15885	COG4770	biotin carboxylase activity
CP970_RS15925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP970_RS15940	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CP970_RS15945	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS15950	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS15985	COG1595	DNA-templated transcription, initiation
CP970_RS15990	COG0745	RESPONSE REGULATOR receiver
CP970_RS15995	COG2205	protein histidine kinase activity
CP970_RS16020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP970_RS16030	COG0583	DNA-binding transcription factor activity
CP970_RS16035	COG2814	Major facilitator Superfamily
CP970_RS16070	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP970_RS16080	COG3845	ABC transporter
CP970_RS16085	COG1744	ABC transporter substrate-binding protein PnrA-like
CP970_RS16090	COG1744	ABC transporter substrate-binding protein PnrA-like
CP970_RS16095	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP970_RS16095	COG1473	amidohydrolase
CP970_RS16165	COG2089	acid synthase
CP970_RS16180	COG1216	Glycosyl transferase, family 2
CP970_RS16190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP970_RS16240	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP970_RS16240	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP970_RS16255	COG1595	DNA-templated transcription, initiation
CP970_RS16290	COG1595	DNA-templated transcription, initiation
CP970_RS16320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP970_RS16330	COG2009	succinate dehydrogenase
CP970_RS16340	COG1053	succinate dehydrogenase
CP970_RS16360	COG1846	Transcriptional regulator
CP970_RS16370	COG2409	Drug exporters of the RND superfamily
CP970_RS16375	COG0745	RESPONSE REGULATOR receiver
CP970_RS16380	COG2205	protein histidine kinase activity
CP970_RS16390	COG1408	metallophosphoesterase
CP970_RS16400	COG1686	Belongs to the peptidase S11 family
CP970_RS16405	COG1295	ribonuclease BN
CP970_RS16420	COG0671	phosphoesterase, PA-phosphatase related
CP970_RS16445	COG0180	Tryptophanyl-tRNA synthetase
CP970_RS16465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP970_RS16470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP970_RS16485	COG2130	NADP-dependent
CP970_RS16490	COG0754	glutathionylspermidine amidase activity
CP970_RS16510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP970_RS16515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS16520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS16525	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CP970_RS16535	COG4176	ABC-type proline glycine betaine transport system permease component
CP970_RS16540	COG4175	Glycine betaine
CP970_RS16540	COG0517	IMP dehydrogenase activity
CP970_RS16550	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS16565	COG1476	TRANSCRIPTIONal
CP970_RS16580	COG0477	Major facilitator Superfamily
CP970_RS16585	COG0039	L-malate dehydrogenase activity
CP970_RS16600	COG2197	response regulator
CP970_RS16605	COG4585	Histidine kinase
CP970_RS16615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP970_RS16625	COG0138	bifunctional purine biosynthesis protein purh
CP970_RS16655	COG0045	succinate-CoA ligase (ADP-forming) activity
CP970_RS16665	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP970_RS16670	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CP970_RS16675	COG0714	Associated with various cellular activities
CP970_RS16690	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP970_RS16700	COG0739	heme binding
CP970_RS16720	COG0791	NLP P60 protein
CP970_RS16735	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CP970_RS16765	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CP970_RS16780	COG2197	response regulator
CP970_RS16820	COG0519	Catalyzes the synthesis of GMP from XMP
CP970_RS16820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP970_RS16850	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS16855	COG2815	serine threonine protein kinase
CP970_RS16855	COG0515	serine threonine protein kinase
CP970_RS16860	COG0515	serine threonine protein kinase
CP970_RS16870	COG0515	serine threonine protein kinase
CP970_RS16885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP970_RS16900	COG0516	GMP reductase activity
CP970_RS16910	COG1595	DNA-templated transcription, initiation
CP970_RS16925	COG0583	DNA-binding transcription factor activity
CP970_RS16935	COG4221	oxidoreductase activity
CP970_RS16940	COG0459	protein refolding
CP970_RS16955	COG0726	polysaccharide deacetylase
CP970_RS16965	COG4941	Belongs to the sigma-70 factor family
CP970_RS16995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP970_RS17020	COG0802	atpase or kinase
CP970_RS17030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP970_RS17045	COG0736	holo-[acyl-carrier-protein] synthase activity
CP970_RS17050	COG1072	(Pantothenic acid kinase))
CP970_RS17060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP970_RS17065	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP970_RS17070	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP970_RS17085	COG0101	tRNA pseudouridine synthase activity
CP970_RS17090	COG0203	ribosomal protein L17
CP970_RS17095	COG0202	RNA polymerase activity
CP970_RS17100	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP970_RS17105	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP970_RS17110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP970_RS17115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP970_RS17135	COG0563	adenylate kinase activity
CP970_RS17145	COG0200	Binds to the 23S rRNA
CP970_RS17150	COG1841	ribosomal large subunit assembly
CP970_RS17155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP970_RS17160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP970_RS17165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP970_RS17170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP970_RS17180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP970_RS17185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP970_RS17190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP970_RS17195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP970_RS17200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP970_RS17205	COG0255	Belongs to the universal ribosomal protein uL29 family
CP970_RS17210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP970_RS17215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP970_RS17220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP970_RS17225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP970_RS17230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP970_RS17235	COG0089	rRNA binding
CP970_RS17240	COG0088	Forms part of the polypeptide exit tunnel
CP970_RS17245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP970_RS17250	COG0051	transcription antitermination factor activity, RNA binding
CP970_RS17255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP970_RS17260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP970_RS17265	COG0049	tRNA binding
CP970_RS17270	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP970_RS17275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP970_RS17305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP970_RS17310	COG0085	RNA polymerase activity
CP970_RS17320	COG0222	ribosome binding
CP970_RS17325	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CP970_RS17340	COG0081	regulation of translation
CP970_RS17345	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CP970_RS17355	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP970_RS17365	COG0436	Aminotransferase
CP970_RS17370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP970_RS17380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP970_RS17385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP970_RS17390	COG0477	Major facilitator Superfamily
CP970_RS17405	COG2030	dehydratase
CP970_RS17410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP970_RS17425	COG0402	S-adenosylhomocysteine deaminase activity
CP970_RS17430	COG0702	epimerase
CP970_RS17450	COG1666	GTP binding
CP970_RS17495	COG3304	Inner membrane component domain
CP970_RS17500	COG0501	Belongs to the peptidase M48B family
CP970_RS17505	COG1007	ATP synthesis coupled electron transport
CP970_RS17510	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP970_RS17515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP970_RS17520	COG0713	ATP synthesis coupled electron transport
CP970_RS17525	COG0839	Belongs to the complex I subunit 6 family
CP970_RS17530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP970_RS17535	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP970_RS17540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP970_RS17545	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP970_RS17550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP970_RS17575	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP970_RS17575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP970_RS17580	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP970_RS17585	COG1733	regulation of RNA biosynthetic process
CP970_RS17590	COG0702	epimerase
CP970_RS17600	COG0702	epimerase
CP970_RS17615	COG1733	regulation of RNA biosynthetic process
CP970_RS17650	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP970_RS17670	COG0142	geranyltranstransferase activity
CP970_RS17675	COG3104	oligopeptide transport
CP970_RS17680	COG2936	dipeptidyl-peptidase activity
CP970_RS17685	COG0561	phosphatase activity
CP970_RS17690	COG0492	ferredoxin-NADP+ reductase activity
CP970_RS17710	COG1007	ATP synthesis coupled electron transport
CP970_RS17720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP970_RS17725	COG0713	ATP synthesis coupled electron transport
CP970_RS17730	COG0839	Belongs to the complex I subunit 6 family
CP970_RS17735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP970_RS17740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP970_RS17745	COG1034	ATP synthesis coupled electron transport
CP970_RS17750	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP970_RS17760	COG0649	NAD binding
CP970_RS17765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP970_RS17770	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP970_RS17780	COG3103	Sh3 type 3 domain protein
CP970_RS17780	COG0791	NLP P60 protein
CP970_RS17780	COG1388	LysM domain
CP970_RS17810	COG2226	methyltransferase
CP970_RS17820	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP970_RS17900	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CP970_RS17915	COG5640	endopeptidase activity
CP970_RS17940	COG2318	DinB family
CP970_RS18125	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP970_RS18130	COG1278	Cold shock
CP970_RS18135	COG4608	Belongs to the ABC transporter superfamily
CP970_RS18145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS18150	COG0601	transmembrane transport
CP970_RS18230	COG0583	DNA-binding transcription factor activity
CP970_RS18240	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS18255	COG0183	Belongs to the thiolase family
CP970_RS18265	COG2030	dehydratase
CP970_RS18270	COG1309	transcriptional regulator
CP970_RS18285	COG1301	dicarboxylic acid transport
CP970_RS18300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP970_RS18310	COG0163	prenyltransferase activity
CP970_RS18320	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP970_RS18330	COG0583	DNA-binding transcription factor activity
CP970_RS18335	COG0697	spore germination
CP970_RS18360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP970_RS18365	COG1333	cytochrome c biogenesis protein
CP970_RS18370	COG0785	Cytochrome C biogenesis protein
CP970_RS18375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP970_RS18385	COG0406	alpha-ribazole phosphatase activity
CP970_RS18390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP970_RS18425	COG1742	UPF0060 membrane protein
CP970_RS18440	COG1690	Belongs to the RtcB family
CP970_RS18460	COG1834	amidinotransferase
CP970_RS18470	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS18475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS18480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP970_RS18490	COG0534	Mate efflux family protein
CP970_RS18525	COG1024	Enoyl-CoA hydratase
CP970_RS18545	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CP970_RS18550	COG0018	arginyl-trna synthetase
CP970_RS18560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP970_RS18595	COG3321	synthase
CP970_RS18595	COG0604	alcohol dehydrogenase
CP970_RS18600	COG0113	porphobilinogen synthase activity
CP970_RS18605	COG1648	precorrin-2 dehydrogenase activity
CP970_RS18605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP970_RS18610	COG0181	hydroxymethylbilane synthase activity
CP970_RS18615	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP970_RS18620	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP970_RS18635	COG1595	DNA-templated transcription, initiation
CP970_RS18670	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP970_RS18685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP970_RS18710	COG0180	Tryptophanyl-tRNA synthetase
CP970_RS18725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP970_RS18735	COG0842	Transport permease protein
CP970_RS18735	COG1129	ABC transporter
CP970_RS18740	COG0659	secondary active sulfate transmembrane transporter activity
CP970_RS18760	COG4991	sh3 domain protein
CP970_RS18765	COG0129	dihydroxy-acid dehydratase activity
CP970_RS18775	COG1082	Xylose isomerase domain protein TIM barrel
CP970_RS18780	COG0248	Ppx GppA phosphatase
CP970_RS18800	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP970_RS18820	COG4585	Histidine kinase
CP970_RS18825	COG1194	a g-specific adenine glycosylase
CP970_RS18830	COG1595	DNA-templated transcription, initiation
CP970_RS18840	COG0745	RESPONSE REGULATOR receiver
CP970_RS18845	COG2205	protein histidine kinase activity
CP970_RS18850	COG0477	Major facilitator Superfamily
CP970_RS18860	COG0739	heme binding
CP970_RS18890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP970_RS18915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP970_RS18925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP970_RS18930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP970_RS18960	COG2197	response regulator
CP970_RS18975	COG0649	NAD binding
CP970_RS19000	COG1174	glycine betaine transport
CP970_RS19005	COG1174	glycine betaine transport
CP970_RS19035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP970_RS19040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CP970_RS19050	COG0667	Aldo Keto reductase
CP970_RS19055	COG0302	gtp cyclohydrolase
CP970_RS19070	COG0037	tRNA processing
CP970_RS19080	COG2027	D-alanyl-D-alanine carboxypeptidase
CP970_RS19085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP970_RS19100	COG0393	Putative heavy-metal-binding
CP970_RS19115	COG0789	Transcriptional regulator
CP970_RS19135	COG2318	DinB family
CP970_RS19140	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS19165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP970_RS19175	COG0254	rRNA binding
CP970_RS19180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP970_RS19185	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP970_RS19190	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP970_RS19200	COG1289	transmembrane transporter activity
CP970_RS19215	COG1136	(ABC) transporter
CP970_RS19230	COG0745	RESPONSE REGULATOR receiver
CP970_RS19235	COG2205	protein histidine kinase activity
CP970_RS19250	COG1136	(ABC) transporter
CP970_RS19260	COG0697	spore germination
CP970_RS19270	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP970_RS19270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP970_RS19275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP970_RS19275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP970_RS19280	COG3903	Transcriptional regulator
CP970_RS19280	COG3629	intracellular signal transduction
CP970_RS19285	COG5002	protein histidine kinase activity
CP970_RS19300	COG4585	Histidine kinase
CP970_RS19340	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP970_RS19345	COG2197	response regulator
CP970_RS19360	COG0596	Alpha beta hydrolase
CP970_RS19365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP970_RS19375	COG2318	DinB family
CP970_RS19400	COG2197	response regulator
CP970_RS19405	COG4585	Histidine kinase
CP970_RS19410	COG1595	DNA-templated transcription, initiation
CP970_RS19445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CP970_RS19450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP970_RS19455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP970_RS19455	COG1754	DNA topoisomerase type I activity
CP970_RS19465	COG2890	protein-(glutamine-N5) methyltransferase activity
CP970_RS19475	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CP970_RS19480	COG2172	sigma factor antagonist activity
CP970_RS19485	COG1366	Belongs to the anti-sigma-factor antagonist family
CP970_RS19490	COG1111	helicase
CP970_RS19490	COG1205	dead DEAH box helicase
CP970_RS19550	COG0659	secondary active sulfate transmembrane transporter activity
CP970_RS19555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP970_RS19560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP970_RS19570	COG2267	carboxylic ester hydrolase activity
CP970_RS19600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP970_RS19625	COG0003	Pfam Anion-transporting ATPase
CP970_RS19645	COG1610	YqeY-like protein
CP970_RS19650	COG1408	metallophosphoesterase
CP970_RS19725	COG0741	lytic transglycosylase activity
CP970_RS19725	COG1196	nuclear chromosome segregation
CP970_RS19725	COG0739	heme binding
CP970_RS19760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP970_RS19760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP970_RS19765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP970_RS19765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP970_RS19805	COG1609	Transcriptional regulator
CP970_RS19890	COG2175	clavaminate synthase activity
CP970_RS19915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP970_RS19980	COG1846	Transcriptional regulator
CP970_RS20000	COG0300	oxidoreductase activity
CP970_RS20010	COG0640	Transcriptional regulator
CP970_RS20015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP970_RS20050	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CP970_RS20070	COG1595	DNA-templated transcription, initiation
CP970_RS20095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP970_RS20100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP970_RS20115	COG0463	Glycosyl transferase, family 2
CP970_RS20120	COG1802	Transcriptional regulator
CP970_RS20125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP970_RS20155	COG0693	protein deglycase activity
CP970_RS20175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP970_RS20180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP970_RS20195	COG1131	(ABC) transporter
CP970_RS20200	COG3559	Exporter of polyketide antibiotics
CP970_RS20210	COG2197	response regulator
CP970_RS20225	COG3844	kynureninase activity
CP970_RS20230	COG3483	tryptophan 2,3-dioxygenase activity
CP970_RS20250	COG0191	fructose-bisphosphate aldolase activity
CP970_RS20255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP970_RS20270	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP970_RS20300	COG0542	response to heat
CP970_RS20365	COG0789	Transcriptional regulator
CP970_RS20370	COG0484	heat shock protein binding
CP970_RS20375	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP970_RS20380	COG0443	Heat shock 70 kDa protein
CP970_RS20385	COG2181	nitrate reductase activity
CP970_RS20385	COG0247	lactate metabolic process
CP970_RS20440	COG0717	Belongs to the dCTP deaminase family
CP970_RS20455	COG2188	Transcriptional regulator
CP970_RS20490	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CP970_RS20515	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS20525	COG1309	transcriptional regulator
CP970_RS20535	COG2201	protein-glutamate methylesterase activity
CP970_RS20585	COG2249	NAD(P)H dehydrogenase (quinone) activity
CP970_RS20600	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS20645	COG2095	MarC family integral membrane protein
CP970_RS20650	COG0583	DNA-binding transcription factor activity
CP970_RS20685	COG1289	transmembrane transporter activity
CP970_RS20695	COG0583	DNA-binding transcription factor activity
CP970_RS20715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP970_RS20745	COG1309	transcriptional regulator
CP970_RS20770	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP970_RS20785	COG1741	Belongs to the pirin family
CP970_RS20795	COG1960	acyl-CoA dehydrogenase activity
CP970_RS20805	COG1362	aminopeptidase activity
CP970_RS20825	COG2271	Major facilitator Superfamily
CP970_RS20830	COG2186	Transcriptional regulator
CP970_RS20840	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP970_RS20845	COG0022	dehydrogenase e1 component
CP970_RS20865	COG0515	serine threonine protein kinase
CP970_RS20870	COG0515	serine threonine protein kinase
CP970_RS20885	COG0604	alcohol dehydrogenase
CP970_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS20885	COG3321	synthase
CP970_RS20890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP970_RS20900	COG0746	molybdenum cofactor guanylyltransferase activity
CP970_RS20920	COG1522	sequence-specific DNA binding
CP970_RS20925	COG1309	transcriptional regulator
CP970_RS20930	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP970_RS20955	COG3396	Phenylacetate-CoA oxygenase
CP970_RS20960	COG3460	Phenylacetate-CoA oxygenase
CP970_RS20965	COG3396	Phenylacetate-CoA oxygenase
CP970_RS20970	COG2151	metal-sulfur cluster biosynthetic enzyme
CP970_RS20975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP970_RS21005	COG1716	ATPase activity
CP970_RS21010	COG1716	ATPase activity
CP970_RS21035	COG0515	serine threonine protein kinase
CP970_RS21045	COG3764	Sortase (surface protein transpeptidase)
CP970_RS21050	COG3764	Sortase (surface protein transpeptidase)
CP970_RS21065	COG3764	Sortase (surface protein transpeptidase)
CP970_RS21080	COG0705	Rhomboid family
CP970_RS21095	COG0477	Major facilitator Superfamily
CP970_RS21100	COG2124	cytochrome p450
CP970_RS21160	COG0515	serine threonine protein kinase
CP970_RS21185	COG2188	Transcriptional regulator
CP970_RS21235	COG2319	Wd-40 repeat
CP970_RS21235	COG4249	Peptidase C14 caspase catalytic subunit p20
CP970_RS21255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP970_RS21265	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP970_RS21270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP970_RS21275	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP970_RS21280	COG0592	DNA-directed DNA polymerase activity
CP970_RS21290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CP970_RS21295	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CP970_RS21300	COG0594	ribonuclease P activity
CP970_RS21305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP970_RS21310	COG0706	membrane insertase activity
CP970_RS21320	COG0357	Ribosomal RNA small subunit methyltransferase G
CP970_RS21330	COG1192	Involved in chromosome partitioning
CP970_RS21345	COG3118	belongs to the thioredoxin family
CP970_RS21350	COG0492	ferredoxin-NADP+ reductase activity
CP970_RS21360	COG1595	DNA-templated transcription, initiation
CP970_RS21380	COG0617	tRNA 3'-terminal CCA addition
CP970_RS21405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP970_RS21430	COG0360	Binds together with S18 to 16S ribosomal RNA
CP970_RS21435	COG0629	single-stranded DNA binding
CP970_RS21440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP970_RS21445	COG0359	binds to the 23S rRNA
CP970_RS21455	COG0305	Participates in initiation and elongation during chromosome replication
CP970_RS21500	COG2814	Major facilitator Superfamily
CP970_RS21540	COG0626	cystathionine gamma-synthase activity
CP970_RS21545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP970_RS21550	COG1950	PFAM Membrane protein of
CP970_RS21555	COG0662	Cupin 2, conserved barrel domain protein
CP970_RS21580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP970_RS21605	COG1609	Transcriptional regulator
CP970_RS21610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP970_RS21615	COG1271	oxidase subunit
CP970_RS21620	COG1294	oxidase, subunit
CP970_RS21625	COG4988	ABC transporter
CP970_RS21640	COG0561	phosphatase activity
CP970_RS21655	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP970_RS21660	COG0789	Transcriptional regulator
CP970_RS21680	COG1131	(ABC) transporter
CP970_RS21710	COG0561	phosphatase activity
CP970_RS21715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP970_RS21725	COG2837	iron assimilation
CP970_RS21740	COG1999	signal sequence binding
CP970_RS21760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP970_RS21765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS21775	COG0006	proline dipeptidase activity
CP970_RS21795	COG0653	protein targeting
CP970_RS21815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP970_RS21855	COG2837	iron assimilation
CP970_RS21885	COG1960	acyl-CoA dehydrogenase activity
CP970_RS21895	COG1960	acyl-CoA dehydrogenase activity
CP970_RS21915	COG1595	DNA-templated transcription, initiation
CP970_RS21920	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS21925	COG0784	Response regulator, receiver
CP970_RS22005	COG2197	response regulator
CP970_RS22035	COG0745	RESPONSE REGULATOR receiver
CP970_RS22040	COG2205	protein histidine kinase activity
CP970_RS22045	COG1215	transferase activity, transferring glycosyl groups
CP970_RS22050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP970_RS22055	COG0477	Major facilitator Superfamily
CP970_RS22085	COG1846	Transcriptional regulator
CP970_RS22100	COG1191	sigma factor activity
CP970_RS22105	COG1191	sigma factor activity
CP970_RS22135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP970_RS22150	COG0433	COG0433 Predicted ATPase
CP970_RS22165	COG0488	(ABC) transporter
CP970_RS22175	COG2268	Band 7 protein
CP970_RS22190	COG0583	DNA-binding transcription factor activity
CP970_RS22195	COG0697	spore germination
CP970_RS22225	COG2326	polyphosphate kinase activity
CP970_RS22365	COG0151	Belongs to the GarS family
CP970_RS22380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP970_RS22390	COG2197	response regulator
CP970_RS22425	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP970_RS22430	COG0047	phosphoribosylformylglycinamidine synthase activity
CP970_RS22435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP970_RS22465	COG3119	arylsulfatase activity
CP970_RS22475	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP970_RS22510	COG1643	Atp-dependent helicase
CP970_RS22520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP970_RS22520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP970_RS22525	COG0785	Cytochrome C biogenesis protein
CP970_RS22615	COG0242	peptide deformylase activity
CP970_RS22630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP970_RS22635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP970_RS22685	COG2226	methyltransferase
CP970_RS22760	COG0477	Major facilitator Superfamily
CP970_RS22785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP970_RS22805	COG0667	Aldo Keto reductase
CP970_RS22815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP970_RS22820	COG0579	oxidoreductase
CP970_RS22850	COG1252	NADH dehydrogenase
CP970_RS22890	COG2197	response regulator
CP970_RS22895	COG4585	Histidine kinase
CP970_RS22905	COG1131	(ABC) transporter
CP970_RS23035	COG1196	nuclear chromosome segregation
CP970_RS23035	COG0741	lytic transglycosylase activity
CP970_RS23035	COG0739	heme binding
CP970_RS23040	COG0671	phosphoesterase, PA-phosphatase related
CP970_RS23045	COG0277	FAD linked oxidase domain protein
CP970_RS23060	COG1937	Protein conserved in bacteria
CP970_RS23070	COG0306	phosphate transporter
CP970_RS23075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP970_RS23090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP970_RS23095	COG0494	nUDIX hydrolase
CP970_RS23095	COG0406	alpha-ribazole phosphatase activity
CP970_RS23105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CP970_RS23125	COG0456	acetyltransferase
CP970_RS23130	COG0737	Belongs to the 5'-nucleotidase family
CP970_RS23155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP970_RS23160	COG1609	Transcriptional regulator
CP970_RS23165	COG0745	RESPONSE REGULATOR receiver
CP970_RS23185	COG2897	thiosulfate sulfurtransferase activity
CP970_RS23205	COG3485	protocatechuate 3,4-dioxygenase
CP970_RS23210	COG0735	belongs to the Fur family
CP970_RS23220	COG1490	D-aminoacyl-tRNA deacylase activity
CP970_RS23230	COG4552	Acetyltransferase involved in intracellular survival and related
CP970_RS23240	COG2186	Transcriptional regulator
CP970_RS23250	COG2188	Transcriptional regulator
CP970_RS23265	COG0546	phosphoglycolate phosphatase activity
CP970_RS23295	COG0768	penicillin binding
CP970_RS23310	COG1902	pentaerythritol trinitrate reductase activity
CP970_RS23330	COG1733	regulation of RNA biosynthetic process
CP970_RS23370	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS23420	COG0438	transferase activity, transferring glycosyl groups
CP970_RS23440	COG0588	phosphoglycerate mutase activity
CP970_RS23485	COG5002	protein histidine kinase activity
CP970_RS23510	COG1329	Transcriptional regulator
CP970_RS23520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP970_RS23525	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP970_RS23530	COG3467	pyridoxamine 5'-phosphate
CP970_RS23535	COG0215	cysteine-tRNA ligase activity
CP970_RS23550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP970_RS23560	COG3842	ATPase activity
CP970_RS23575	COG0702	epimerase
CP970_RS23580	COG3631	Ketosteroid isomerase-related protein
CP970_RS23585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP970_RS23620	COG4552	Acetyltransferase involved in intracellular survival and related
CP970_RS23645	COG2197	response regulator
CP970_RS23660	COG0666	response to abiotic stimulus
CP970_RS23675	COG0456	acetyltransferase
CP970_RS23725	COG2226	methyltransferase
CP970_RS23765	COG1228	amidohydrolase
CP970_RS23795	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CP970_RS23805	COG0463	Glycosyl transferase, family 2
CP970_RS23810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP970_RS23830	COG1115	amino acid carrier protein
CP970_RS23880	COG1263	PTS System
CP970_RS23880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP970_RS23885	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP970_RS23890	COG1737	Transcriptional regulator
CP970_RS23925	COG0110	maltose O-acetyltransferase activity
CP970_RS23950	COG3973	AAA domain
CP970_RS23970	COG1061	Type III restriction enzyme res subunit
CP970_RS24005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP970_RS24010	COG1120	ATPase activity
CP970_RS24015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS24020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS24035	COG1278	Cold shock
CP970_RS24040	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP970_RS24045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP970_RS24055	COG2814	Major facilitator Superfamily
CP970_RS24080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP970_RS24090	COG2252	PERMEase
CP970_RS24115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CP970_RS24120	COG0667	Aldo Keto reductase
CP970_RS24175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP970_RS24210	COG0277	FAD linked oxidase domain protein
CP970_RS24210	COG0247	lactate metabolic process
CP970_RS24225	COG0583	DNA-binding transcription factor activity
CP970_RS24245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP970_RS24290	COG0259	pyridoxamine-phosphate oxidase activity
CP970_RS24295	COG2945	thiolester hydrolase activity
CP970_RS24295	COG0596	Alpha beta hydrolase
CP970_RS24305	COG4821	SIS domain
CP970_RS24310	COG2205	protein histidine kinase activity
CP970_RS24315	COG0745	RESPONSE REGULATOR receiver
CP970_RS24330	COG0577	efflux transmembrane transporter activity
CP970_RS24330	COG1136	(ABC) transporter
CP970_RS24335	COG0577	efflux transmembrane transporter activity
CP970_RS24335	COG1136	(ABC) transporter
CP970_RS24410	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS24415	COG1960	acyl-CoA dehydrogenase activity
CP970_RS24420	COG1960	acyl-CoA dehydrogenase activity
CP970_RS24440	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS24445	COG1960	acyl-CoA dehydrogenase activity
CP970_RS24480	COG1024	Enoyl-CoA hydratase
CP970_RS24490	COG2072	flavoprotein involved in K transport
CP970_RS24510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP970_RS24520	COG0259	pyridoxamine-phosphate oxidase activity
CP970_RS24530	COG1960	acyl-CoA dehydrogenase activity
CP970_RS24540	COG1309	transcriptional regulator
CP970_RS24545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP970_RS24545	COG0515	serine threonine protein kinase
CP970_RS24560	COG1024	Enoyl-CoA hydratase
CP970_RS24660	COG3903	Transcriptional regulator
CP970_RS24660	COG3629	intracellular signal transduction
CP970_RS24675	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS24685	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP970_RS24745	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP970_RS24775	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS24800	COG1686	Belongs to the peptidase S11 family
CP970_RS24840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP970_RS24845	COG5640	endopeptidase activity
CP970_RS24860	COG1309	transcriptional regulator
CP970_RS24865	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS24875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CP970_RS24875	COG2124	cytochrome p450
CP970_RS24965	COG0778	Nitroreductase
CP970_RS24970	COG1846	Transcriptional regulator
CP970_RS24975	COG1535	isochorismatase
CP970_RS24975	COG3433	isochorismatase activity
CP970_RS24980	COG1535	isochorismatase
CP970_RS24980	COG3433	isochorismatase activity
CP970_RS24985	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP970_RS24990	COG1169	isochorismate synthase
CP970_RS24995	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS25000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS25005	COG2382	esterase
CP970_RS25010	COG0477	Major facilitator Superfamily
CP970_RS25020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS25030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP970_RS25035	COG1120	ATPase activity
CP970_RS25040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CP970_RS25060	COG1846	Transcriptional regulator
CP970_RS25065	COG3384	dioxygenase
CP970_RS25075	COG1247	-acetyltransferase
CP970_RS25090	COG0477	Major facilitator Superfamily
CP970_RS25105	COG1420	regulation of RNA biosynthetic process
CP970_RS25140	COG1609	Transcriptional regulator
CP970_RS25200	COG3191	aminopeptidase activity
CP970_RS25215	COG2146	nitrite reductase [NAD(P)H] activity
CP970_RS25215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP970_RS25220	COG2223	nitrite transmembrane transporter activity
CP970_RS25230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP970_RS25235	COG2223	nitrite transmembrane transporter activity
CP970_RS25245	COG1970	mechanosensitive ion channel activity
CP970_RS25255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP970_RS25275	COG3263	regulation of cellular component size
CP970_RS25280	COG2366	antibiotic biosynthetic process
CP970_RS25285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP970_RS25290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP970_RS25300	COG0315	cyclic pyranopterin monophosphate synthase activity
CP970_RS25305	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP970_RS25310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP970_RS25355	COG2205	protein histidine kinase activity
CP970_RS25365	COG0708	Exodeoxyribonuclease III
CP970_RS25380	COG2072	flavoprotein involved in K transport
CP970_RS25385	COG2267	carboxylic ester hydrolase activity
CP970_RS25390	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS25400	COG0793	Belongs to the peptidase S41A family
CP970_RS25400	COG4946	Tricorn protease homolog
CP970_RS25410	COG2409	Drug exporters of the RND superfamily
CP970_RS25420	COG0310	cobalt ion transport
CP970_RS25430	COG1122	ATPase activity
CP970_RS25455	COG0768	penicillin binding
CP970_RS25480	COG0084	hydrolase, TatD family'
CP970_RS25485	COG3584	3D domain protein
CP970_RS25485	COG3583	domain protein
CP970_RS25490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP970_RS25495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP970_RS25505	COG0488	(ABC) transporter
CP970_RS25545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP970_RS25555	COG2197	response regulator
CP970_RS25560	COG1846	Transcriptional regulator
CP970_RS25565	COG4106	trans-aconitate 2-methyltransferase activity
CP970_RS25590	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP970_RS25605	COG0193	aminoacyl-tRNA hydrolase activity
CP970_RS25610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP970_RS25615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP970_RS25620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP970_RS25630	COG4585	Histidine kinase
CP970_RS25655	COG1316	TRANSCRIPTIONal
CP970_RS25670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP970_RS25680	COG0477	Major facilitator Superfamily
CP970_RS25685	COG1136	(ABC) transporter
CP970_RS25690	COG0577	efflux transmembrane transporter activity
CP970_RS25765	COG2124	cytochrome p450
CP970_RS25770	COG1652	LysM domain
CP970_RS25780	COG0148	phosphopyruvate hydratase activity
CP970_RS25800	COG1252	NADH dehydrogenase
CP970_RS25805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP970_RS25810	COG0577	efflux transmembrane transporter activity
CP970_RS25815	COG1136	(ABC) transporter
CP970_RS25825	COG1414	Transcriptional regulator
CP970_RS25835	COG2814	Major facilitator Superfamily
CP970_RS25860	COG0183	Belongs to the thiolase family
CP970_RS25865	COG2755	lipolytic protein G-D-S-L family
CP970_RS25880	COG4221	oxidoreductase activity
CP970_RS25890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CP970_RS25905	COG1174	glycine betaine transport
CP970_RS25915	COG2986	histidine ammonia-lyase
CP970_RS25955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP970_RS25960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP970_RS25970	COG1228	amidohydrolase
CP970_RS25975	COG2197	response regulator
CP970_RS26005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP970_RS26020	COG1131	(ABC) transporter
CP970_RS26030	COG2197	response regulator
CP970_RS26035	COG4585	Histidine kinase
CP970_RS26080	COG1191	sigma factor activity
CP970_RS26085	COG1366	Belongs to the anti-sigma-factor antagonist family
CP970_RS26120	COG3104	oligopeptide transport
CP970_RS26125	COG0745	RESPONSE REGULATOR receiver
CP970_RS26130	COG2205	protein histidine kinase activity
CP970_RS26160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP970_RS26185	COG1316	TRANSCRIPTIONal
CP970_RS26210	COG1316	TRANSCRIPTIONal
CP970_RS26215	COG1316	TRANSCRIPTIONal
CP970_RS26230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP970_RS26240	COG0778	Nitroreductase
CP970_RS26240	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP970_RS26245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP970_RS26290	COG1620	l-lactate permease
CP970_RS26295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP970_RS26300	COG2835	tetraacyldisaccharide 4'-kinase activity
CP970_RS26310	COG1482	cell wall glycoprotein biosynthetic process
CP970_RS26320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP970_RS26320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP970_RS26320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP970_RS26325	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP970_RS26365	COG0714	Associated with various cellular activities
CP970_RS26385	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP970_RS26445	COG2188	Transcriptional regulator
CP970_RS26450	COG0456	acetyltransferase
CP970_RS26470	COG0745	RESPONSE REGULATOR receiver
CP970_RS26480	COG0823	Involved in the tonB-independent uptake of proteins
CP970_RS26490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP970_RS26495	COG2197	response regulator
CP970_RS26500	COG3214	Protein conserved in bacteria
CP970_RS26510	COG0653	protein targeting
CP970_RS26545	COG0463	Glycosyl transferase, family 2
CP970_RS26545	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP970_RS26550	COG1134	teichoic acid transport
CP970_RS26570	COG2197	response regulator
CP970_RS26595	COG1136	(ABC) transporter
CP970_RS26595	COG0577	efflux transmembrane transporter activity
CP970_RS26620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP970_RS26625	COG0463	Glycosyl transferase, family 2
CP970_RS26625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP970_RS26630	COG0438	transferase activity, transferring glycosyl groups
CP970_RS26650	COG0463	Glycosyl transferase, family 2
CP970_RS26650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP970_RS26655	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP970_RS26660	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP970_RS26665	COG0463	Glycosyl transferase, family 2
CP970_RS26665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP970_RS26670	COG0395	ABC-type sugar transport system, permease component
CP970_RS26675	COG1175	transmembrane transport
CP970_RS26690	COG0515	serine threonine protein kinase
CP970_RS26695	COG0515	serine threonine protein kinase
CP970_RS26700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP970_RS26715	COG2884	Cell division ATP-binding protein ftsE
CP970_RS26725	COG0793	Belongs to the peptidase S41A family
CP970_RS26730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP970_RS26740	COG2027	D-alanyl-D-alanine carboxypeptidase
CP970_RS26750	COG0583	DNA-binding transcription factor activity
CP970_RS26760	COG2910	NAD(P)H-binding
CP970_RS26765	COG0697	spore germination
CP970_RS26770	COG1846	Transcriptional regulator
CP970_RS26800	COG2223	nitrite transmembrane transporter activity
CP970_RS26830	COG3973	AAA domain
CP970_RS26845	COG0776	regulation of translation
CP970_RS26850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP970_RS26855	COG1678	Uncharacterized ACR, COG1678
CP970_RS26860	COG0583	DNA-binding transcription factor activity
CP970_RS26865	COG2814	Major facilitator Superfamily
CP970_RS26875	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP970_RS26890	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP970_RS26905	COG1404	Belongs to the peptidase S8 family
CP970_RS26920	COG2124	cytochrome p450
CP970_RS26930	COG2318	DinB family
CP970_RS26995	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP970_RS27015	COG1174	glycine betaine transport
CP970_RS27025	COG1174	glycine betaine transport
CP970_RS27035	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP970_RS27060	COG0277	FAD linked oxidase domain protein
CP970_RS27095	COG1335	isochorismatase
CP970_RS27105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP970_RS27115	COG1113	amino acid transport
CP970_RS27130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS27135	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP970_RS27160	COG1234	tRNA 3'-trailer cleavage
CP970_RS27170	COG1263	PTS System
CP970_RS27175	COG1263	PTS System
CP970_RS27180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP970_RS27185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP970_RS27200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP970_RS27210	COG0477	Major facilitator Superfamily
CP970_RS27235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP970_RS27250	COG4555	ABC transporter
CP970_RS27295	COG3764	Sortase (surface protein transpeptidase)
CP970_RS27305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP970_RS27325	COG0706	membrane insertase activity
CP970_RS27360	COG4702	Belongs to the UPF0303 family
CP970_RS27365	COG0673	inositol 2-dehydrogenase activity
CP970_RS27380	COG2188	Transcriptional regulator
CP970_RS27385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP970_RS27450	COG2186	Transcriptional regulator
CP970_RS27475	COG3397	chitin binding
CP970_RS27480	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS27505	COG2201	protein-glutamate methylesterase activity
CP970_RS27510	COG4585	Histidine kinase
CP970_RS27515	COG0586	Pfam SNARE associated Golgi protein
CP970_RS27530	COG1126	abc transporter atp-binding protein
CP970_RS27535	COG0765	amino acid transport
CP970_RS27540	COG0765	amino acid transport
CP970_RS27555	COG0154	amidase activity
CP970_RS27560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP970_RS27565	COG3473	Maleate cis-trans isomerase
CP970_RS27585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS27635	COG0406	alpha-ribazole phosphatase activity
CP970_RS27660	COG0745	RESPONSE REGULATOR receiver
CP970_RS27665	COG2205	protein histidine kinase activity
CP970_RS27685	COG2985	domain, Protein
CP970_RS27750	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CP970_RS27755	COG4977	sequence-specific DNA binding
CP970_RS27765	COG0589	response to stress
CP970_RS27775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP970_RS27805	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP970_RS27820	COG1960	acyl-CoA dehydrogenase activity
CP970_RS27835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP970_RS27840	COG1309	transcriptional regulator
CP970_RS27850	COG1946	Acyl-CoA thioesterase
CP970_RS27870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP970_RS27880	COG0028	Belongs to the TPP enzyme family
CP970_RS27910	COG1472	Belongs to the glycosyl hydrolase 3 family
CP970_RS27920	COG0456	acetyltransferase
CP970_RS27920	COG1846	Transcriptional regulator
CP970_RS27930	COG1280	lysine exporter protein (LysE YggA)
CP970_RS27945	COG0673	inositol 2-dehydrogenase activity
CP970_RS27965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP970_RS28000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP970_RS28010	COG3718	enzyme involved in inositol metabolism
CP970_RS28015	COG3962	Belongs to the TPP enzyme family
CP970_RS28035	COG1131	(ABC) transporter
CP970_RS28095	COG1316	TRANSCRIPTIONal
CP970_RS28145	COG0438	transferase activity, transferring glycosyl groups
CP970_RS28165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP970_RS28170	COG0297	glycogen (starch) synthase activity
CP970_RS28220	COG2304	oxidoreductase activity
CP970_RS28240	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP970_RS28250	COG1309	transcriptional regulator
CP970_RS28290	COG0745	RESPONSE REGULATOR receiver
CP970_RS28295	COG5002	protein histidine kinase activity
CP970_RS28325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP970_RS28330	COG0629	single-stranded DNA binding
CP970_RS28360	COG1136	(ABC) transporter
CP970_RS28375	COG2346	COG2346, Truncated hemoglobins
CP970_RS28380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP970_RS28425	COG1486	melibiose metabolic process
CP970_RS28430	COG0395	ABC-type sugar transport system, permease component
CP970_RS28435	COG1175	transmembrane transport
CP970_RS28445	COG1846	Transcriptional regulator
CP970_RS28445	COG1940	carbohydrate kinase activity
CP970_RS28495	COG0668	transmembrane transport
CP970_RS28530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS28560	COG0583	DNA-binding transcription factor activity
CP970_RS28635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP970_RS28640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP970_RS28645	COG1113	amino acid transport
CP970_RS28650	COG1113	amino acid transport
CP970_RS28655	COG1268	BioY protein
CP970_RS28665	COG1113	amino acid transport
CP970_RS28680	COG4552	Acetyltransferase involved in intracellular survival and related
CP970_RS28690	COG0475	glutathione-regulated potassium exporter activity
CP970_RS28695	COG1136	(ABC) transporter
CP970_RS28715	COG3594	Acyltransferase
CP970_RS28725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP970_RS28730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP970_RS28730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP970_RS28745	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP970_RS28750	COG0740	serine-type endopeptidase activity
CP970_RS28755	COG0740	serine-type endopeptidase activity
CP970_RS28760	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP970_RS28780	COG0525	valine-tRNA ligase activity
CP970_RS28800	COG2205	protein histidine kinase activity
CP970_RS28810	COG4585	Histidine kinase
CP970_RS28815	COG1077	Cell shape determining protein MreB Mrl
CP970_RS28820	COG0285	dihydrofolate synthase activity
CP970_RS28830	COG0105	UTP biosynthetic process
CP970_RS28835	COG1077	Cell shape determining protein MreB Mrl
CP970_RS28855	COG0772	Belongs to the SEDS family
CP970_RS28885	COG1530	ribonuclease E activity
CP970_RS28895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP970_RS28900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP970_RS28905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP970_RS28915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP970_RS28925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP970_RS28950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP970_RS28960	COG0799	negative regulation of ribosome biogenesis
CP970_RS28965	COG0588	phosphoglycerate mutase activity
CP970_RS28980	COG0477	Major facilitator Superfamily
CP970_RS29020	COG0495	leucyl-tRNA aminoacylation
CP970_RS29030	COG1307	EDD domain protein, DegV family
CP970_RS29035	COG1555	photosystem II stabilization
CP970_RS29040	COG1234	tRNA 3'-trailer cleavage
CP970_RS29050	COG2353	YceI-like domain
CP970_RS29065	COG0268	Binds directly to 16S ribosomal RNA
CP970_RS29070	COG0481	GTPase activity
CP970_RS29110	COG1420	regulation of RNA biosynthetic process
CP970_RS29115	COG0484	heat shock protein binding
CP970_RS29135	COG4946	Tricorn protease homolog
CP970_RS29135	COG0793	Belongs to the peptidase S41A family
CP970_RS29140	COG0537	adenosine 5'-monophosphoramidase activity
CP970_RS29145	COG1234	tRNA 3'-trailer cleavage
CP970_RS29150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP970_RS29160	COG4948	Mandelate Racemase Muconate Lactonizing
CP970_RS29165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP970_RS29175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP970_RS29185	COG2315	Protein conserved in bacteria
CP970_RS29215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP970_RS29225	COG2723	6-phospho-beta-galactosidase activity
CP970_RS29245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP970_RS29255	COG2409	Drug exporters of the RND superfamily
CP970_RS29260	COG4585	Histidine kinase
CP970_RS29265	COG2197	response regulator
CP970_RS29275	COG4608	Belongs to the ABC transporter superfamily
CP970_RS29280	COG0444	Belongs to the ABC transporter superfamily
CP970_RS29290	COG0747	negative chemotaxis
CP970_RS29295	COG2186	Transcriptional regulator
CP970_RS29315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP970_RS29325	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CP970_RS29335	COG0596	Alpha beta hydrolase
CP970_RS29385	COG1381	Involved in DNA repair and RecF pathway recombination
CP970_RS29390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP970_RS29400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP970_RS29405	COG1121	(ABC) transporter
CP970_RS29410	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP970_RS29410	COG3443	Belongs to the bacterial solute-binding protein 9 family
CP970_RS29415	COG0423	glycine-tRNA ligase activity
CP970_RS29450	COG0477	Major facilitator Superfamily
CP970_RS29460	COG1051	belongs to the nudix hydrolase family
CP970_RS29465	COG0494	nUDIX hydrolase
CP970_RS29490	COG0667	Aldo Keto reductase
CP970_RS29500	COG0477	Major facilitator Superfamily
CP970_RS29520	COG0174	glutamine synthetase
CP970_RS29530	COG4689	acetoacetate decarboxylase
CP970_RS29545	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP970_RS29550	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS29575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP970_RS29580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP970_RS29580	COG0574	Belongs to the PEP-utilizing enzyme family
CP970_RS29585	COG1846	Transcriptional regulator
CP970_RS29585	COG1940	carbohydrate kinase activity
CP970_RS29590	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CP970_RS29600	COG0395	ABC-type sugar transport system, permease component
CP970_RS29610	COG1653	transport
CP970_RS29630	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS29635	COG1309	transcriptional regulator
CP970_RS29645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP970_RS29645	COG2146	nitrite reductase [NAD(P)H] activity
CP970_RS29650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP970_RS29695	COG2205	protein histidine kinase activity
CP970_RS29715	COG2949	membrane
CP970_RS29725	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP970_RS29735	COG0358	DNA primase activity
CP970_RS29740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP970_RS29755	COG1070	Carbohydrate kinase
CP970_RS29780	COG3585	molybdate ion transport
CP970_RS29810	COG1077	Cell shape determining protein MreB Mrl
CP970_RS29815	COG1404	Belongs to the peptidase S8 family
CP970_RS29820	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS29835	COG2855	membrane
CP970_RS29845	COG0583	DNA-binding transcription factor activity
CP970_RS29850	COG0515	serine threonine protein kinase
CP970_RS29865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP970_RS29880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP970_RS29890	COG4981	capsule polysaccharide biosynthetic process
CP970_RS29925	COG2130	NADP-dependent
CP970_RS29930	COG1764	response to oxidative stress
CP970_RS29990	COG1309	transcriptional regulator
CP970_RS30015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS30020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP970_RS30025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP970_RS30040	COG1741	Belongs to the pirin family
CP970_RS30055	COG0789	Transcriptional regulator
CP970_RS30060	COG0667	Aldo Keto reductase
CP970_RS30075	COG2197	response regulator
CP970_RS30080	COG4585	Histidine kinase
CP970_RS30095	COG1309	transcriptional regulator
CP970_RS30100	COG0477	Major facilitator Superfamily
CP970_RS30115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP970_RS30120	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP970_RS30165	COG1358	cellular component organization or biogenesis
CP970_RS30185	COG0800	Aldolase
CP970_RS30235	COG2353	YceI-like domain
CP970_RS30365	COG2186	Transcriptional regulator
CP970_RS30425	COG4122	O-methyltransferase activity
CP970_RS30450	COG2124	cytochrome p450
CP970_RS30455	COG0183	Belongs to the thiolase family
CP970_RS30475	COG3845	ABC transporter
CP970_RS30510	COG0515	serine threonine protein kinase
CP970_RS30520	COG1132	(ABC) transporter
CP970_RS30525	COG1132	(ABC) transporter
CP970_RS30530	COG1309	transcriptional regulator
CP970_RS30535	COG0438	transferase activity, transferring glycosyl groups
CP970_RS30560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS30570	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP970_RS30580	COG0477	Major facilitator Superfamily
CP970_RS30585	COG1960	acyl-CoA dehydrogenase activity
CP970_RS30590	COG0183	Belongs to the thiolase family
CP970_RS30605	COG2197	response regulator
CP970_RS30610	COG4585	Histidine kinase
CP970_RS30620	COG1131	(ABC) transporter
CP970_RS30625	COG2030	dehydratase
CP970_RS30635	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS30650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP970_RS30655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP970_RS30670	COG0800	Aldolase
CP970_RS30675	COG3022	response to hydroperoxide
CP970_RS30750	COG1819	glycosyl
CP970_RS30760	COG1819	glycosyl
CP970_RS30780	COG1819	glycosyl
CP970_RS30825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS30830	COG2197	response regulator
CP970_RS30885	COG2259	Doxx family
CP970_RS30895	COG0384	phenazine biosynthesis protein PhzF
CP970_RS30910	COG3540	Alkaline phosphatase
CP970_RS30915	COG2814	Major facilitator Superfamily
CP970_RS30920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP970_RS30945	COG1834	amidinotransferase
CP970_RS30980	COG0672	)-iron permease
CP970_RS30985	COG2837	iron assimilation
CP970_RS30995	COG1120	ATPase activity
CP970_RS31000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS31005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP970_RS31060	COG1994	Peptidase M50
CP970_RS31085	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP970_RS31090	COG0477	Major facilitator Superfamily
CP970_RS31105	COG2814	Major facilitator Superfamily
CP970_RS31110	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP970_RS31110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP970_RS31115	COG2132	Multicopper oxidase
CP970_RS31125	COG0531	amino acid
CP970_RS31140	COG1609	Transcriptional regulator
CP970_RS31150	COG0395	ABC-type sugar transport system, permease component
CP970_RS31155	COG4209	transmembrane transport
CP970_RS31175	COG1959	2 iron, 2 sulfur cluster binding
CP970_RS31180	COG1017	nitric oxide dioxygenase activity
CP970_RS31180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP970_RS31185	COG0174	glutamine synthetase
CP970_RS31210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP970_RS31215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP970_RS31225	COG2124	cytochrome p450
CP970_RS31235	COG1609	Transcriptional regulator
CP970_RS31240	COG0366	Alpha amylase catalytic
CP970_RS31245	COG3833	ABC-type maltose transport systems, permease component
CP970_RS31250	COG1175	transmembrane transport
CP970_RS31285	COG1309	transcriptional regulator
CP970_RS31320	COG2197	response regulator
CP970_RS31325	COG4585	Histidine kinase
CP970_RS31330	COG2409	Drug exporters of the RND superfamily
CP970_RS31340	COG0745	RESPONSE REGULATOR receiver
CP970_RS31405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS31410	COG1120	ATPase activity
CP970_RS31415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP970_RS31420	COG1032	radical SAM domain protein
CP970_RS31435	COG1285	pathogenesis
CP970_RS31450	COG0647	UMP catabolic process
CP970_RS31495	COG1609	Transcriptional regulator
CP970_RS31540	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP970_RS31545	COG0321	lipoyl(octanoyl) transferase activity
CP970_RS31610	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP970_RS31620	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP970_RS31625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP970_RS31630	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP970_RS31635	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP970_RS31650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP970_RS31650	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP970_RS31655	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP970_RS31675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP970_RS31680	COG2226	methyltransferase
CP970_RS31700	COG4585	Histidine kinase
CP970_RS31705	COG2197	response regulator
CP970_RS31710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP970_RS31725	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP970_RS31750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP970_RS31760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP970_RS31765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP970_RS31775	COG1376	ErfK ybiS ycfS ynhG family protein
CP970_RS31785	COG1845	cytochrome c oxidase, subunit III
CP970_RS31790	COG2010	Cytochrome c
CP970_RS31795	COG0723	plastoquinol--plastocyanin reductase activity
CP970_RS31800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP970_RS31805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP970_RS31810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP970_RS31815	COG1929	Belongs to the glycerate kinase type-1 family
CP970_RS31825	COG0745	RESPONSE REGULATOR receiver
CP970_RS31830	COG2205	protein histidine kinase activity
CP970_RS31860	COG0791	NLP P60 protein
CP970_RS31900	COG0003	Pfam Anion-transporting ATPase
CP970_RS31910	COG1940	carbohydrate kinase activity
CP970_RS31925	COG1595	DNA-templated transcription, initiation
CP970_RS31945	COG4585	Histidine kinase
CP970_RS31955	COG0205	6-phosphofructokinase activity
CP970_RS31960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP970_RS31970	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP970_RS31975	COG0243	molybdopterin cofactor binding
CP970_RS31980	COG2193	ferroxidase activity
CP970_RS31985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP970_RS31995	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP970_RS32000	COG0515	serine threonine protein kinase
CP970_RS32000	COG2815	serine threonine protein kinase
CP970_RS32005	COG2022	thiamine diphosphate biosynthetic process
CP970_RS32015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP970_RS32015	COG2022	thiamine diphosphate biosynthetic process
CP970_RS32030	COG0352	thiamine-phosphate diphosphorylase activity
CP970_RS32055	COG1309	transcriptional regulator
CP970_RS32065	COG1129	ABC transporter
CP970_RS32095	COG0714	Associated with various cellular activities
CP970_RS32105	COG0275	rRNA processing
CP970_RS32120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP970_RS32130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP970_RS32135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP970_RS32145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP970_RS32150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP970_RS32155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP970_RS32160	COG1496	oxidoreductase activity
CP970_RS32170	COG1799	cell septum assembly
CP970_RS32185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP970_RS32200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP970_RS32255	COG0587	DNA-directed DNA polymerase activity
CP970_RS32270	COG1432	Conserved Protein
CP970_RS32290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP970_RS32310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP970_RS32315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP970_RS32320	COG0131	Imidazoleglycerol-phosphate dehydratase
CP970_RS32325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP970_RS32330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP970_RS32335	COG0251	oxidation-reduction process
CP970_RS32340	COG0107	imidazoleglycerol-phosphate synthase activity
CP970_RS32365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP970_RS32370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP970_RS32390	COG0134	indole-3-glycerol-phosphate synthase activity
CP970_RS32395	COG0133	tryptophan synthase activity
CP970_RS32400	COG0159	tryptophan synthase activity
CP970_RS32410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CP970_RS32420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP970_RS32425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP970_RS32455	COG0070	glutamate synthase
CP970_RS32455	COG0069	glutamate synthase activity
CP970_RS32455	COG0067	glutamate synthase
CP970_RS32470	COG1175	transmembrane transport
CP970_RS32475	COG0395	ABC-type sugar transport system, permease component
CP970_RS32505	COG2365	Tyrosine phosphatase family
CP970_RS32510	COG1846	Transcriptional regulator
CP970_RS32515	COG0477	Major facilitator Superfamily
CP970_RS32520	COG1278	Cold shock
CP970_RS32530	COG1357	PFAM Pentapeptide repeats (8 copies)
CP970_RS32545	COG1470	cell adhesion involved in biofilm formation
CP970_RS32545	COG0366	Alpha amylase catalytic
CP970_RS32560	COG0287	Prephenate dehydrogenase
CP970_RS32560	COG1605	Chorismate mutase
CP970_RS32570	COG0702	epimerase
CP970_RS32590	COG0737	Belongs to the 5'-nucleotidase family
CP970_RS32660	COG2050	protein possibly involved in aromatic compounds catabolism
CP970_RS32695	COG1643	Atp-dependent helicase
CP970_RS32700	COG2226	methyltransferase
CP970_RS32720	COG0237	dephospho-CoA kinase activity
CP970_RS32780	COG2267	carboxylic ester hydrolase activity
CP970_RS32810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP970_RS32855	COG0402	S-adenosylhomocysteine deaminase activity
CP970_RS32880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CP970_RS32885	COG0022	dehydrogenase e1 component
CP970_RS32935	COG0598	Magnesium transport protein CorA
CP970_RS32940	COG2226	methyltransferase
CP970_RS32945	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CP970_RS32945	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CP970_RS32950	COG2313	pseudouridylate synthase activity
CP970_RS32965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP970_RS32970	COG0584	glycerophosphoryl diester phosphodiesterase
CP970_RS32980	COG0556	nucleotide-excision repair
CP970_RS33000	COG0387	Pfam Sodium calcium exchanger
CP970_RS33010	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP970_RS33025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP970_RS33030	COG1024	Enoyl-CoA hydratase
CP970_RS33035	COG2353	YceI-like domain
CP970_RS33045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP970_RS33050	COG0723	plastoquinol--plastocyanin reductase activity
CP970_RS33075	COG1595	DNA-templated transcription, initiation
CP970_RS33085	COG0322	excinuclease ABC activity
CP970_RS33090	COG1660	Displays ATPase and GTPase activities
CP970_RS33095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP970_RS33100	COG1481	regulation of sporulation
CP970_RS33110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP970_RS33115	COG0126	phosphoglycerate kinase activity
CP970_RS33120	COG0149	triose-phosphate isomerase activity
CP970_RS33125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP970_RS33135	COG0166	Belongs to the GPI family
CP970_RS33145	COG0363	glucosamine-6-phosphate deaminase activity
CP970_RS33160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP970_RS33170	COG0109	protoheme IX farnesyltransferase activity
CP970_RS33210	COG1131	(ABC) transporter
CP970_RS33215	COG2116	formate transmembrane transporter activity
CP970_RS33220	COG2746	aminoglycoside 3-N-acetyltransferase activity
CP970_RS33235	COG0719	Fe-S assembly protein
CP970_RS33245	COG0396	ATPase activity
CP970_RS33250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP970_RS33255	COG0822	iron-sulfur transferase activity
CP970_RS33265	COG2076	Multidrug Resistance protein
CP970_RS33270	COG3226	Transcriptional regulator
CP970_RS33285	COG2171	N-acyltransferase activity
CP970_RS33370	COG1595	DNA-templated transcription, initiation
CP970_RS33380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP970_RS33485	COG1063	alcohol dehydrogenase
CP970_RS33505	COG1349	DNA-binding transcription factor activity
CP970_RS33515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP970_RS33520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP970_RS33555	COG1695	Transcriptional regulator
CP970_RS33570	COG2197	response regulator
CP970_RS33575	COG4585	Histidine kinase
CP970_RS33590	COG1414	Transcriptional regulator
CP970_RS33605	COG0673	inositol 2-dehydrogenase activity
CP970_RS33610	COG1733	regulation of RNA biosynthetic process
CP970_RS33635	COG1846	Transcriptional regulator
CP970_RS33640	COG1902	pentaerythritol trinitrate reductase activity
CP970_RS33645	COG5285	phytanoyl-CoA dioxygenase
CP970_RS33650	COG1917	Cupin 2, conserved barrel domain protein
CP970_RS33655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP970_RS33660	COG0456	acetyltransferase
CP970_RS33665	COG2318	DinB family
CP970_RS33695	COG1797	cobyrinic acid a,c-diamide synthase activity
CP970_RS33710	COG1492	cobalamin metabolic process
CP970_RS33715	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CP970_RS33735	COG0235	Class ii aldolase
CP970_RS33765	COG0488	(ABC) transporter
CP970_RS33875	COG1063	alcohol dehydrogenase
CP970_RS33885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP970_RS33905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP970_RS33910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP970_RS33930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP970_RS33945	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS33950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP970_RS33960	COG2186	Transcriptional regulator
CP970_RS33985	COG0560	Phosphoserine phosphatase
CP970_RS33985	COG3830	Belongs to the UPF0237 family
CP970_RS33995	COG1131	(ABC) transporter
CP970_RS33995	COG0842	Transport permease protein
CP970_RS33995	COG1716	ATPase activity
CP970_RS34005	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CP970_RS34010	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS34020	COG2197	response regulator
CP970_RS34040	COG1119	ATPase activity
CP970_RS34060	COG1881	PFAM PEBP family protein
CP970_RS34070	COG2094	Belongs to the DNA glycosylase MPG family
CP970_RS34100	COG0647	UMP catabolic process
CP970_RS34105	COG2375	cellular response to nickel ion
CP970_RS34105	COG1132	(ABC) transporter
CP970_RS34120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS34125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS34130	COG1120	ATPase activity
CP970_RS34150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP970_RS34160	COG0497	DNA recombination
CP970_RS34165	COG0297	glycogen (starch) synthase activity
CP970_RS34175	COG3387	PFAM Glycoside hydrolase 15-related
CP970_RS34180	COG0504	CTP synthase activity
CP970_RS34185	COG0494	nUDIX hydrolase
CP970_RS34195	COG0686	Belongs to the AlaDH PNT family
CP970_RS34210	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP970_RS34215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP970_RS34220	COG1187	pseudouridine synthase activity
CP970_RS34225	COG1051	belongs to the nudix hydrolase family
CP970_RS34225	COG1056	cytidyltransferase-related domain
CP970_RS34270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP970_RS34280	COG1160	GTP binding
CP970_RS34300	COG3583	domain protein
CP970_RS34310	COG1137	ATPase activity
CP970_RS34330	COG0438	transferase activity, transferring glycosyl groups
CP970_RS34355	COG0671	phosphoesterase, PA-phosphatase related
CP970_RS34365	COG0477	Major facilitator Superfamily
CP970_RS34370	COG1960	acyl-CoA dehydrogenase activity
CP970_RS34375	COG1799	cell septum assembly
CP970_RS34390	COG0765	amino acid transport
CP970_RS34405	COG1126	abc transporter atp-binding protein
CP970_RS34410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP970_RS34415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS34420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS34435	COG0330	HflC and HflK could
CP970_RS34445	COG1454	alcohol dehydrogenase
CP970_RS34445	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS34465	COG0587	DNA-directed DNA polymerase activity
CP970_RS34470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP970_RS34485	COG4585	Histidine kinase
CP970_RS34490	COG2197	response regulator
CP970_RS34515	COG4565	transcriptional regulatory protein
CP970_RS34540	COG2226	methyltransferase
CP970_RS34555	COG1725	Transcriptional regulator
CP970_RS34575	COG1649	PFAM Uncharacterised BCR, COG1649
CP970_RS34575	COG0726	polysaccharide deacetylase
CP970_RS34580	COG1216	Glycosyl transferase, family 2
CP970_RS34585	COG0463	Glycosyl transferase, family 2
CP970_RS34600	COG2755	lipolytic protein G-D-S-L family
CP970_RS34645	COG2197	response regulator
CP970_RS34660	COG2188	Transcriptional regulator
CP970_RS34665	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CP970_RS34670	COG1309	transcriptional regulator
CP970_RS34675	COG0243	molybdopterin cofactor binding
CP970_RS34680	COG2851	Citrate transporter
CP970_RS34735	COG0640	Transcriptional regulator
CP970_RS34745	COG1960	acyl-CoA dehydrogenase activity
CP970_RS34765	COG0789	Transcriptional regulator
CP970_RS34800	COG0477	Major facilitator Superfamily
CP970_RS34810	COG3876	Protein conserved in bacteria
CP970_RS34820	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS34830	COG1960	acyl-CoA dehydrogenase activity
CP970_RS34860	COG2149	membrane
CP970_RS34865	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP970_RS34885	COG3573	Dehydrogenase
CP970_RS34915	COG3265	gluconokinase activity
CP970_RS34925	COG3012	SEC-C Motif Domain Protein
CP970_RS34930	COG0753	catalase activity
CP970_RS34940	COG0028	Belongs to the TPP enzyme family
CP970_RS34975	COG0531	amino acid
CP970_RS34990	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP970_RS34995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP970_RS35000	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP970_RS35020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP970_RS35045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP970_RS35050	COG0667	Aldo Keto reductase
CP970_RS35055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS35075	COG0598	Magnesium transport protein CorA
CP970_RS35095	COG0215	cysteine-tRNA ligase activity
CP970_RS35110	COG1404	Belongs to the peptidase S8 family
CP970_RS35110	COG4935	Belongs to the peptidase S8 family
CP970_RS35120	COG2186	Transcriptional regulator
CP970_RS35125	COG1846	Transcriptional regulator
CP970_RS35175	COG0346	lactoylglutathione lyase activity
CP970_RS35180	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS35185	COG0477	Major facilitator Superfamily
CP970_RS35195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP970_RS35200	COG0402	S-adenosylhomocysteine deaminase activity
CP970_RS35210	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP970_RS35215	COG4603	Belongs to the binding-protein-dependent transport system permease family
CP970_RS35220	COG3845	ABC transporter
CP970_RS35230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP970_RS35230	COG0235	Class ii aldolase
CP970_RS35240	COG0235	Class ii aldolase
CP970_RS35245	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CP970_RS35250	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CP970_RS35255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS35260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP970_RS35265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP970_RS35270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP970_RS35275	COG1414	Transcriptional regulator
CP970_RS35280	COG1410	methionine synthase
CP970_RS35280	COG0646	methionine synthase
CP970_RS35285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP970_RS35290	COG4166	transmembrane transport
CP970_RS35295	COG0747	negative chemotaxis
CP970_RS35300	COG2197	response regulator
CP970_RS35310	COG1994	Peptidase M50
CP970_RS35310	COG0517	IMP dehydrogenase activity
CP970_RS35335	COG1222	aaa ATPase
CP970_RS35340	COG4122	O-methyltransferase activity
CP970_RS35355	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP970_RS35360	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP970_RS35365	COG1609	Transcriptional regulator
CP970_RS35375	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP970_RS35390	COG2378	regulation of single-species biofilm formation
CP970_RS35410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP970_RS35415	COG0805	protein transport
CP970_RS35430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS35475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP970_RS35480	COG0517	IMP dehydrogenase activity
CP970_RS35480	COG4175	Glycine betaine
CP970_RS35515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP970_RS35530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP970_RS35535	COG0531	amino acid
CP970_RS35545	COG0174	glutamine synthetase
CP970_RS35550	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS35555	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS35565	COG0560	Phosphoserine phosphatase
CP970_RS35565	COG3830	Belongs to the UPF0237 family
CP970_RS35600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP970_RS35605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP970_RS35610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP970_RS35615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP970_RS35620	COG5002	protein histidine kinase activity
CP970_RS35625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP970_RS35630	COG0072	phenylalanine-tRNA ligase activity
CP970_RS35630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP970_RS35660	COG1649	PFAM Uncharacterised BCR, COG1649
CP970_RS35670	COG0697	spore germination
CP970_RS35675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP970_RS35680	COG0456	acetyltransferase
CP970_RS35680	COG0454	-acetyltransferase
CP970_RS35695	COG0667	Aldo Keto reductase
CP970_RS35710	COG0477	Major facilitator Superfamily
CP970_RS35735	COG1131	(ABC) transporter
CP970_RS35745	COG2197	response regulator
CP970_RS35765	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CP970_RS35775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP970_RS35780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP970_RS35785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP970_RS35790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP970_RS35795	COG1438	arginine binding
CP970_RS35800	COG0385	Bile acid
CP970_RS35820	COG0137	argininosuccinate synthase activity
CP970_RS35825	COG0165	Argininosuccinate lyase
CP970_RS35840	COG0477	Major facilitator Superfamily
CP970_RS35845	COG0204	Acyl-transferase
CP970_RS35845	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS35850	COG0584	glycerophosphoryl diester phosphodiesterase
CP970_RS35880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP970_RS35885	COG2011	ABC-type metal ion transport system permease component
CP970_RS35890	COG1464	Belongs to the NlpA lipoprotein family
CP970_RS35895	COG1464	Belongs to the NlpA lipoprotein family
CP970_RS35910	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP970_RS35915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP970_RS35915	COG1648	precorrin-2 dehydrogenase activity
CP970_RS35980	COG0512	Glutamine amidotransferase of anthranilate synthase
CP970_RS35980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP970_RS35985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP970_RS36050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP970_RS36065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP970_RS36095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP970_RS36100	COG1560	Kdo2-lipid A biosynthetic process
CP970_RS36105	COG0438	transferase activity, transferring glycosyl groups
CP970_RS36115	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP970_RS36120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP970_RS36125	COG0217	transcriptional regulatory protein
CP970_RS36130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP970_RS36135	COG0632	four-way junction helicase activity
CP970_RS36140	COG2255	four-way junction helicase activity
CP970_RS36150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP970_RS36155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP970_RS36160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP970_RS36170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP970_RS36175	COG1196	nuclear chromosome segregation
CP970_RS36180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP970_RS36190	COG0124	histidyl-tRNA synthetase
CP970_RS36200	COG1131	(ABC) transporter
CP970_RS36220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP970_RS36240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP970_RS36245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP970_RS36255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP970_RS36260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP970_RS36265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP970_RS36270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP970_RS36275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP970_RS36285	COG0006	proline dipeptidase activity
CP970_RS36290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP970_RS36295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP970_RS36305	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP970_RS36310	COG0540	Belongs to the ATCase OTCase family
CP970_RS36315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP970_RS36325	COG0505	Belongs to the CarA family
CP970_RS36330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP970_RS36335	COG0167	dihydroorotate dehydrogenase activity
CP970_RS36340	COG0284	orotidine-5'-phosphate decarboxylase activity
CP970_RS36350	COG0194	GDP metabolic process
CP970_RS36365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP970_RS36400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP970_RS36420	COG1309	transcriptional regulator
CP970_RS36425	COG2409	Drug exporters of the RND superfamily
CP970_RS36430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP970_RS36435	COG2390	Transcriptional regulator
CP970_RS36455	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS36460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS36465	COG0531	amino acid
CP970_RS36485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP970_RS36510	COG2233	PERMEase
CP970_RS36515	COG0738	Major facilitator superfamily
CP970_RS36520	COG1940	carbohydrate kinase activity
CP970_RS36520	COG1846	Transcriptional regulator
CP970_RS36530	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP970_RS36550	COG0477	Major facilitator Superfamily
CP970_RS36560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS36575	COG3321	synthase
CP970_RS36575	COG0604	alcohol dehydrogenase
CP970_RS36595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS36615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP970_RS36665	COG0604	alcohol dehydrogenase
CP970_RS36665	COG3321	synthase
CP970_RS36675	COG3321	synthase
CP970_RS36675	COG0604	alcohol dehydrogenase
CP970_RS36725	COG3201	nicotinamide mononucleotide transporter
CP970_RS36730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP970_RS36730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP970_RS36735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP970_RS36740	COG0140	phosphoribosyl-ATP diphosphatase activity
CP970_RS36745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP970_RS36770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP970_RS36780	COG1595	DNA-templated transcription, initiation
CP970_RS36820	COG1309	transcriptional regulator
CP970_RS36830	COG1960	acyl-CoA dehydrogenase activity
CP970_RS36865	COG0463	Glycosyl transferase, family 2
CP970_RS36880	COG2270	Major facilitator Superfamily
CP970_RS36890	COG2364	Membrane
CP970_RS36895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP970_RS36935	COG0438	transferase activity, transferring glycosyl groups
CP970_RS36940	COG2755	lipolytic protein G-D-S-L family
CP970_RS36945	COG1984	allophanate hydrolase subunit 2
CP970_RS36950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP970_RS36955	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP970_RS36960	COG4336	lyase activity
CP970_RS36965	COG2814	Major facilitator Superfamily
CP970_RS36990	COG4638	Rieske (2fe-2S)
CP970_RS36995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP970_RS37010	COG1414	Transcriptional regulator
CP970_RS37020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP970_RS37055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP970_RS37060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP970_RS37065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP970_RS37075	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CP970_RS37090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP970_RS37100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP970_RS37135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP970_RS37175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP970_RS37185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP970_RS37185	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP970_RS37215	COG0384	phenazine biosynthesis protein PhzF
CP970_RS37220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP970_RS37225	COG1695	Transcriptional regulator
CP970_RS37230	COG0124	histidyl-tRNA synthetase
CP970_RS37235	COG2890	protein-(glutamine-N5) methyltransferase activity
CP970_RS37250	COG0697	spore germination
CP970_RS37265	COG0697	spore germination
CP970_RS37270	COG0583	DNA-binding transcription factor activity
CP970_RS37315	COG4166	transmembrane transport
CP970_RS37320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP970_RS37360	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP970_RS37370	COG2816	NAD+ diphosphatase activity
CP970_RS37385	COG0477	Major facilitator Superfamily
CP970_RS37415	COG1968	undecaprenyl-diphosphatase activity
CP970_RS37425	COG0183	Belongs to the thiolase family
CP970_RS37445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP970_RS37465	COG2003	Belongs to the UPF0758 family
CP970_RS37510	COG1674	ftsk spoiiie
CP970_RS37580	COG4106	trans-aconitate 2-methyltransferase activity
CP970_RS37610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP970_RS37640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP970_RS37680	COG1472	Belongs to the glycosyl hydrolase 3 family
CP970_RS37685	COG2272	Belongs to the type-B carboxylesterase lipase family
CP970_RS37720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP970_RS37725	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CP970_RS37745	COG0702	epimerase
CP970_RS37755	COG1522	sequence-specific DNA binding
CP970_RS37760	COG0252	asparaginase activity
CP970_RS37770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP970_RS37800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP970_RS37805	COG1309	transcriptional regulator
CP970_RS37820	COG1609	Transcriptional regulator
CP970_RS37825	COG1653	transport
CP970_RS37835	COG0395	ABC-type sugar transport system, permease component
CP970_RS37845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP970_RS37850	COG1349	DNA-binding transcription factor activity
CP970_RS37860	COG3979	chitinase
CP970_RS37890	COG0473	3-isopropylmalate dehydrogenase activity
CP970_RS37895	COG0583	DNA-binding transcription factor activity
CP970_RS37905	COG0745	RESPONSE REGULATOR receiver
CP970_RS37910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP970_RS37930	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS37935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS37940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS37945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP970_RS37950	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS37985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP970_RS37995	COG2040	homocysteine
CP970_RS38005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS38020	COG1940	carbohydrate kinase activity
CP970_RS38040	COG1902	pentaerythritol trinitrate reductase activity
CP970_RS38045	COG0640	Transcriptional regulator
CP970_RS38070	COG1309	transcriptional regulator
CP970_RS38090	COG0671	phosphoesterase, PA-phosphatase related
CP970_RS38115	COG1846	Transcriptional regulator
CP970_RS38120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP970_RS38125	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS38145	COG4106	trans-aconitate 2-methyltransferase activity
CP970_RS38160	COG0584	glycerophosphoryl diester phosphodiesterase
CP970_RS38170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP970_RS38195	COG0596	Alpha beta hydrolase
CP970_RS38205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP970_RS38225	COG2233	PERMEase
CP970_RS38250	COG1064	alcohol dehydrogenase
CP970_RS38270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS38275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS38285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS38285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS38295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS38300	COG0657	acetylesterase activity
CP970_RS38330	COG0204	Acyl-transferase
CP970_RS38350	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP970_RS38365	COG0515	serine threonine protein kinase
CP970_RS38405	COG3345	alpha-galactosidase
CP970_RS38420	COG0395	ABC-type sugar transport system, permease component
CP970_RS38435	COG1309	transcriptional regulator
CP970_RS38450	COG1316	TRANSCRIPTIONal
CP970_RS38455	COG2205	protein histidine kinase activity
CP970_RS38470	COG1116	anion transmembrane transporter activity
CP970_RS38495	COG1660	Displays ATPase and GTPase activities
CP970_RS38510	COG0445	tRNA wobble uridine modification
CP970_RS38525	COG4585	Histidine kinase
CP970_RS38530	COG2197	response regulator
CP970_RS38560	COG1940	carbohydrate kinase activity
CP970_RS38605	COG1136	(ABC) transporter
CP970_RS38610	COG0577	efflux transmembrane transporter activity
CP970_RS38625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP970_RS38635	COG1349	DNA-binding transcription factor activity
CP970_RS38670	COG1215	transferase activity, transferring glycosyl groups
CP970_RS38675	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CP970_RS38710	COG2813	Specifically methylates the guanine in position
CP970_RS38735	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP970_RS38735	COG1902	pentaerythritol trinitrate reductase activity
CP970_RS38790	COG1461	Dihydroxyacetone kinase
CP970_RS38795	COG2376	Dihydroxyacetone kinase
CP970_RS38845	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CP970_RS38865	COG1174	glycine betaine transport
CP970_RS38870	COG1174	glycine betaine transport
CP970_RS38885	COG1556	Lactate utilization protein
CP970_RS38890	COG1139	Iron-sulfur cluster binding protein
CP970_RS38895	COG0247	lactate metabolic process
CP970_RS38900	COG1609	Transcriptional regulator
CP970_RS38915	COG1024	Enoyl-CoA hydratase
CP970_RS38920	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS38930	COG0492	ferredoxin-NADP+ reductase activity
CP970_RS38945	COG1960	acyl-CoA dehydrogenase activity
CP970_RS38950	COG1960	acyl-CoA dehydrogenase activity
CP970_RS38965	COG0601	transmembrane transport
CP970_RS38970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS38975	COG0444	Belongs to the ABC transporter superfamily
CP970_RS39000	COG1349	DNA-binding transcription factor activity
CP970_RS39005	COG2814	Major facilitator Superfamily
CP970_RS39015	COG1070	Carbohydrate kinase
CP970_RS39020	COG0588	phosphoglycerate mutase activity
CP970_RS39025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP970_RS39065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP970_RS39080	COG4172	Belongs to the ABC transporter superfamily
CP970_RS39115	COG0019	diaminopimelate decarboxylase activity
CP970_RS39150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CP970_RS39155	COG0277	FAD linked oxidase domain protein
CP970_RS39155	COG0247	lactate metabolic process
CP970_RS39170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS39175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS39215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP970_RS39220	COG0477	Major facilitator Superfamily
CP970_RS39235	COG0659	secondary active sulfate transmembrane transporter activity
CP970_RS39250	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP970_RS39280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP970_RS39285	COG2066	Belongs to the glutaminase family
CP970_RS39305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP970_RS39330	COG0546	phosphoglycolate phosphatase activity
CP970_RS39340	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS39345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS39380	COG0438	transferase activity, transferring glycosyl groups
CP970_RS39385	COG0366	Alpha amylase catalytic
CP970_RS39400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP970_RS39405	COG2188	Transcriptional regulator
CP970_RS39415	COG1120	ATPase activity
CP970_RS39420	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CP970_RS39470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP970_RS39495	COG1136	(ABC) transporter
CP970_RS39500	COG0577	efflux transmembrane transporter activity
CP970_RS39500	COG1136	(ABC) transporter
CP970_RS39510	COG3250	beta-galactosidase activity
CP970_RS39535	COG0488	(ABC) transporter
CP970_RS39540	COG0488	(ABC) transporter
CP970_RS39565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP970_RS39575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP970_RS39600	COG1960	acyl-CoA dehydrogenase activity
CP970_RS39605	COG5285	phytanoyl-CoA dioxygenase
CP970_RS39610	COG2226	methyltransferase
CP970_RS39620	COG3903	Transcriptional regulator
CP970_RS39620	COG3629	intracellular signal transduction
CP970_RS39655	COG1819	glycosyl
CP970_RS39665	COG0702	epimerase
CP970_RS39690	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CP970_RS39700	COG1132	(ABC) transporter
CP970_RS39705	COG1309	transcriptional regulator
CP970_RS39710	COG0702	epimerase
CP970_RS39770	COG2124	cytochrome p450
CP970_RS39775	COG4221	oxidoreductase activity
CP970_RS39810	COG1131	(ABC) transporter
CP970_RS39810	COG1716	ATPase activity
CP970_RS39810	COG0842	Transport permease protein
CP970_RS39830	COG2375	cellular response to nickel ion
CP970_RS39835	COG4592	Periplasmic binding protein
CP970_RS39845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS39850	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP970_RS39855	COG1012	belongs to the aldehyde dehydrogenase family
CP970_RS39875	COG1940	carbohydrate kinase activity
CP970_RS39880	COG1070	Carbohydrate kinase
CP970_RS39900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP970_RS39905	COG3239	Fatty acid desaturase
CP970_RS39945	COG2226	methyltransferase
CP970_RS39980	COG2018	Roadblock/LC7 domain
CP970_RS40000	COG1946	Acyl-CoA thioesterase
CP970_RS40015	COG1132	(ABC) transporter
CP970_RS40020	COG1132	(ABC) transporter
CP970_RS40025	COG1132	(ABC) transporter
CP970_RS40030	COG1132	(ABC) transporter
CP970_RS40050	COG0277	FAD linked oxidase domain protein
CP970_RS40060	COG1132	(ABC) transporter
CP970_RS40075	COG2072	flavoprotein involved in K transport
CP970_RS40085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP970_RS40095	COG3321	synthase
CP970_RS40095	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS40095	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS40095	COG0300	oxidoreductase activity
CP970_RS40095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS40115	COG1116	anion transmembrane transporter activity
CP970_RS40120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP970_RS40125	COG0432	Pfam Uncharacterised protein family UPF0047
CP970_RS40140	COG2197	response regulator
CP970_RS40160	COG0277	FAD linked oxidase domain protein
CP970_RS40165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP970_RS40170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP970_RS40175	COG2814	Major facilitator Superfamily
CP970_RS40185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP970_RS40195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS40205	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CP970_RS40220	COG0017	Asparaginyl-tRNA synthetase
CP970_RS40225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS40230	COG2175	clavaminate synthase activity
CP970_RS40235	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS40250	COG0069	glutamate synthase activity
CP970_RS40270	COG2264	protein methyltransferase activity
CP970_RS40290	COG0009	L-threonylcarbamoyladenylate synthase
CP970_RS40295	COG3903	Transcriptional regulator
CP970_RS40295	COG3629	intracellular signal transduction
CP970_RS40325	COG2080	2 iron, 2 sulfur cluster binding
CP970_RS40330	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP970_RS40335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP970_RS40360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP970_RS40380	COG0542	response to heat
CP970_RS40395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP970_RS40435	COG1832	CoA-binding protein
CP970_RS40480	COG1739	Uncharacterized protein family UPF0029
CP970_RS40485	COG0420	3'-5' exonuclease activity
CP970_RS40490	COG0419	ATPase involved in DNA repair
CP970_RS40510	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS40520	COG3547	Transposase (IS116 IS110 IS902 family)
CP970_RS40620	COG1522	sequence-specific DNA binding
CP970_RS40635	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS40650	COG0626	cystathionine gamma-synthase activity
CP970_RS40670	COG0346	lactoylglutathione lyase activity
CP970_RS40680	COG1595	DNA-templated transcription, initiation
CP970_RS40685	COG2188	Transcriptional regulator
CP970_RS40690	COG1940	carbohydrate kinase activity
CP970_RS40695	COG2197	response regulator
CP970_RS40700	COG4585	Histidine kinase
CP970_RS40720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CP970_RS40755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP970_RS40775	COG0488	(ABC) transporter
CP970_RS40790	COG0456	acetyltransferase
CP970_RS40805	COG1136	(ABC) transporter
CP970_RS40805	COG0577	efflux transmembrane transporter activity
CP970_RS40825	COG2226	methyltransferase
CP970_RS40830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP970_RS40835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP970_RS40840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP970_RS40865	COG0583	DNA-binding transcription factor activity
CP970_RS40870	COG1280	lysine exporter protein (LysE YggA)
CP970_RS40875	COG0791	NLP P60 protein
CP970_RS40885	COG0740	serine-type endopeptidase activity
CP970_RS40905	COG1309	transcriptional regulator
CP970_RS40910	COG0831	urea catabolic process
CP970_RS40915	COG0832	Belongs to the urease beta subunit family
CP970_RS40920	COG0804	urea catabolic process
CP970_RS40925	COG0830	nickel cation binding
CP970_RS40930	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP970_RS40935	COG0829	nickel cation binding
CP970_RS40960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP970_RS40970	COG0204	Acyl-transferase
CP970_RS40990	COG0205	6-phosphofructokinase activity
CP970_RS40995	COG3442	glutamine amidotransferase
CP970_RS41005	COG0242	peptide deformylase activity
CP970_RS41015	COG1960	acyl-CoA dehydrogenase activity
CP970_RS41025	COG0477	Major facilitator Superfamily
CP970_RS41030	COG1335	isochorismatase
CP970_RS41055	COG2814	Major facilitator Superfamily
CP970_RS41090	COG0583	DNA-binding transcription factor activity
CP970_RS41095	COG4941	Belongs to the sigma-70 factor family
CP970_RS41115	COG2409	Drug exporters of the RND superfamily
CP970_RS41130	COG2175	clavaminate synthase activity
CP970_RS41155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP970_RS41195	COG0330	HflC and HflK could
CP970_RS41210	COG0022	dehydrogenase e1 component
CP970_RS41215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CP970_RS41220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS41225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP970_RS41280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS41320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP970_RS41325	COG2409	Drug exporters of the RND superfamily
CP970_RS41330	COG1733	regulation of RNA biosynthetic process
CP970_RS41335	COG0702	epimerase
CP970_RS41375	COG2755	lipolytic protein G-D-S-L family
CP970_RS41385	COG1132	(ABC) transporter
CP970_RS41430	COG2197	response regulator
CP970_RS41430	COG3903	Transcriptional regulator
CP970_RS41465	COG1175	transmembrane transport
CP970_RS41470	COG0395	ABC-type sugar transport system, permease component
CP970_RS41500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP970_RS41525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP970_RS41535	COG5564	TIM-barrel signal transduction protein
CP970_RS41550	COG2340	Cysteine-rich secretory protein family
CP970_RS41555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP970_RS41560	COG1073	alpha beta
CP970_RS41565	COG0318	PFAM AMP-dependent synthetase and ligase
CP970_RS41565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS41565	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS41565	COG3321	synthase
CP970_RS41565	COG0300	oxidoreductase activity
CP970_RS41570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP970_RS41605	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CP970_RS41615	COG3973	AAA domain
CP970_RS41620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP970_RS41635	COG0477	Major facilitator Superfamily
CP970_RS41685	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS41695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP970_RS41700	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP970_RS41705	COG2080	2 iron, 2 sulfur cluster binding
CP970_RS41715	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP970_RS41720	COG1228	amidohydrolase
CP970_RS41725	COG2197	response regulator
CP970_RS41845	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP970_RS41850	COG2197	response regulator
CP970_RS41855	COG4585	Histidine kinase
CP970_RS41860	COG1136	(ABC) transporter
CP970_RS41860	COG0577	efflux transmembrane transporter activity
CP970_RS41875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS41885	COG1595	DNA-templated transcription, initiation
CP970_RS41950	COG2814	Major facilitator Superfamily
CP970_RS41970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP970_RS41990	COG0367	asparagine synthase
CP970_RS42025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP970_RS42040	COG4310	Domain of unknown function (DUF2172)
CP970_RS42050	COG1216	Glycosyl transferase, family 2
CP970_RS42050	COG0463	Glycosyl transferase, family 2
CP970_RS42060	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CP970_RS42065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP970_RS42095	COG0784	Response regulator, receiver
CP970_RS42095	COG5002	protein histidine kinase activity
CP970_RS42175	COG1113	amino acid transport
CP970_RS42190	COG3795	YCII-related domain
CP970_RS42195	COG4941	Belongs to the sigma-70 factor family
CP970_RS42200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP970_RS42215	COG0596	Alpha beta hydrolase
CP970_RS42235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP970_RS42255	COG0702	epimerase
CP970_RS42280	COG1595	DNA-templated transcription, initiation
CP970_RS42330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP970_RS42350	COG3594	Acyltransferase
CP970_RS42365	COG0789	Transcriptional regulator
CP970_RS42385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP970_RS42395	COG1028	Short-chain dehydrogenase reductase Sdr
CP970_RS42490	COG1175	transmembrane transport
CP970_RS42500	COG0366	Alpha amylase catalytic
CP970_RS42530	COG0006	proline dipeptidase activity
CP970_RS42560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CP970_RS42575	COG3395	kinase activity
CP970_RS42585	COG3622	Belongs to the hyi family
CP970_RS42600	COG0513	Belongs to the DEAD box helicase family
CP970_RS42610	COG3896	Chloramphenicol phosphotransferase-like protein
CP970_RS42625	COG1132	(ABC) transporter
CP970_RS42635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP970_RS42665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP970_RS42710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP970_RS42770	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CP970_RS42785	COG0180	Tryptophanyl-tRNA synthetase
CP970_RS42800	COG1819	glycosyl
CP970_RS42805	COG2318	DinB family
CP970_RS42875	COG1136	(ABC) transporter
CP970_RS42880	COG0577	efflux transmembrane transporter activity
CP970_RS42885	COG0745	RESPONSE REGULATOR receiver
CP970_RS42890	COG2205	protein histidine kinase activity
CP970_RS42910	COG2815	serine threonine protein kinase
CP970_RS42910	COG0515	serine threonine protein kinase
CP970_RS42925	COG2045	Belongs to the ComB family
CP970_RS42940	COG0667	Aldo Keto reductase
CP970_RS42955	COG0010	Belongs to the arginase family
CP970_RS42960	COG0367	asparagine synthase
CP970_RS42980	COG1349	DNA-binding transcription factor activity
CP970_RS43015	COG0328	RNA-DNA hybrid ribonuclease activity
CP970_RS43025	COG2197	response regulator
CP970_RS43055	COG3655	Transcriptional regulator
CP970_RS43095	COG0667	Aldo Keto reductase
CP970_RS43100	COG1522	sequence-specific DNA binding
CP970_RS43160	COG2318	DinB family
CP970_RS43170	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CP970_RS43185	COG0789	Transcriptional regulator
CP970_RS43195	COG0640	Transcriptional regulator
CP970_RS43210	COG3903	Transcriptional regulator
CP970_RS43210	COG2197	response regulator
CP970_RS43215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CP970_RS43225	COG2124	cytochrome p450
CP970_RS43260	COG2124	cytochrome p450
CP970_RS43275	COG0730	response to heat
CP970_RS43280	COG1937	Protein conserved in bacteria
CP970_RS43285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP970_RS43310	COG0778	Nitroreductase
CP970_RS43335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP970_RS43370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP970_RS43405	COG1024	Enoyl-CoA hydratase
CP970_RS43410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP970_RS43445	COG2205	protein histidine kinase activity
CP970_RS43450	COG0745	RESPONSE REGULATOR receiver
CP970_RS43460	COG1686	Belongs to the peptidase S11 family
CP970_RS43615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP970_RS43660	COG2124	cytochrome p450
CP970_RS43665	COG0142	geranyltranstransferase activity
CP970_RS43670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP970_RS43675	COG0463	Glycosyl transferase, family 2
CP970_RS43820	COG4249	Peptidase C14 caspase catalytic subunit p20
CP970_RS43820	COG2319	Wd-40 repeat
CP970_RS43925	COG0556	nucleotide-excision repair