locus-tag	class	description
SLAV_RS00055	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS00070	COG1215	transferase activity, transferring glycosyl groups
SLAV_RS00155	COG0791	NLP P60 protein
SLAV_RS00155	COG0741	lytic transglycosylase activity
SLAV_RS00245	COG2188	Transcriptional regulator
SLAV_RS00265	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLAV_RS00305	COG3547	Transposase (IS116 IS110 IS902 family)
SLAV_RS00335	COG1660	Displays ATPase and GTPase activities
SLAV_RS00340	COG0181	hydroxymethylbilane synthase activity
SLAV_RS00515	COG1404	Belongs to the peptidase S8 family
SLAV_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS00580	COG0017	Asparaginyl-tRNA synthetase
SLAV_RS00590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS00615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS00660	COG4585	Histidine kinase
SLAV_RS00665	COG2197	response regulator
SLAV_RS00770	COG2197	response regulator
SLAV_RS00775	COG4585	Histidine kinase
SLAV_RS00860	COG3293	Transposase
SLAV_RS00885	COG1609	Transcriptional regulator
SLAV_RS00900	COG0395	ABC-type sugar transport system, permease component
SLAV_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLAV_RS00915	COG1940	carbohydrate kinase activity
SLAV_RS00920	COG1105	Belongs to the carbohydrate kinase PfkB family
SLAV_RS00970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLAV_RS00970	COG0515	serine threonine protein kinase
SLAV_RS00980	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLAV_RS00980	COG0515	serine threonine protein kinase
SLAV_RS01090	COG1278	Cold shock
SLAV_RS01110	COG2226	methyltransferase
SLAV_RS01135	COG5634	Uncharacterized conserved protein (DUF2278)
SLAV_RS01195	COG2801	Transposase and inactivated derivatives
SLAV_RS01200	COG3415	Transposase
SLAV_RS01200	COG2801	Transposase and inactivated derivatives
SLAV_RS01390	COG0667	Aldo Keto reductase
SLAV_RS01480	COG0069	glutamate synthase activity
SLAV_RS01485	COG0028	Belongs to the TPP enzyme family
SLAV_RS01500	COG1295	ribonuclease BN
SLAV_RS01550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLAV_RS01570	COG0667	Aldo Keto reductase
SLAV_RS01575	COG1309	transcriptional regulator
SLAV_RS01605	COG2319	Wd-40 repeat
SLAV_RS01605	COG4249	Peptidase C14 caspase catalytic subunit p20
SLAV_RS01660	COG1280	lysine exporter protein (LysE YggA)
SLAV_RS01695	COG2205	protein histidine kinase activity
SLAV_RS01700	COG0745	RESPONSE REGULATOR receiver
SLAV_RS01715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLAV_RS01730	COG2340	Cysteine-rich secretory protein family
SLAV_RS01745	COG1686	Belongs to the peptidase S11 family
SLAV_RS01775	COG0300	oxidoreductase activity
SLAV_RS01780	COG2124	cytochrome p450
SLAV_RS01795	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS01800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SLAV_RS01830	COG1595	DNA-templated transcription, initiation
SLAV_RS01900	COG0477	Major facilitator Superfamily
SLAV_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS02030	COG2353	YceI-like domain
SLAV_RS02060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLAV_RS02080	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLAV_RS02115	COG0346	lactoylglutathione lyase activity
SLAV_RS02120	COG1595	DNA-templated transcription, initiation
SLAV_RS02175	COG1940	carbohydrate kinase activity
SLAV_RS02180	COG0531	amino acid
SLAV_RS02205	COG0656	L-ascorbic acid biosynthetic process
SLAV_RS02235	COG3903	Transcriptional regulator
SLAV_RS02235	COG3629	intracellular signal transduction
SLAV_RS02380	COG1522	sequence-specific DNA binding
SLAV_RS02450	COG0583	DNA-binding transcription factor activity
SLAV_RS02490	COG1228	amidohydrolase
SLAV_RS02500	COG2267	carboxylic ester hydrolase activity
SLAV_RS02505	COG2259	Doxx family
SLAV_RS02510	COG1335	isochorismatase
SLAV_RS02520	COG4221	oxidoreductase activity
SLAV_RS02540	COG2378	regulation of single-species biofilm formation
SLAV_RS02565	COG3415	Transposase
SLAV_RS02565	COG2801	Transposase and inactivated derivatives
SLAV_RS02580	COG0277	FAD linked oxidase domain protein
SLAV_RS02600	COG0395	ABC-type sugar transport system, permease component
SLAV_RS02605	COG1175	transmembrane transport
SLAV_RS02610	COG2182	Extracellular solute-binding protein
SLAV_RS02630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SLAV_RS02640	COG1609	Transcriptional regulator
SLAV_RS02650	COG0395	ABC-type sugar transport system, permease component
SLAV_RS02660	COG1653	transport
SLAV_RS02690	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS02710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLAV_RS02730	COG1595	DNA-templated transcription, initiation
SLAV_RS02775	COG1846	Transcriptional regulator
SLAV_RS02785	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SLAV_RS02795	COG1737	Transcriptional regulator
SLAV_RS02845	COG3321	synthase
SLAV_RS02845	COG0604	alcohol dehydrogenase
SLAV_RS02925	COG2045	Belongs to the ComB family
SLAV_RS02940	COG1309	transcriptional regulator
SLAV_RS02945	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS02955	COG0662	Cupin 2, conserved barrel domain protein
SLAV_RS02975	COG0517	IMP dehydrogenase activity
SLAV_RS02975	COG4175	Glycine betaine
SLAV_RS02985	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS02990	COG1309	transcriptional regulator
SLAV_RS02995	COG0300	oxidoreductase activity
SLAV_RS03000	COG0640	Transcriptional regulator
SLAV_RS03005	COG0477	Major facilitator Superfamily
SLAV_RS03020	COG1309	transcriptional regulator
SLAV_RS03050	COG1902	pentaerythritol trinitrate reductase activity
SLAV_RS03065	COG4941	Belongs to the sigma-70 factor family
SLAV_RS03070	COG3795	YCII-related domain
SLAV_RS03105	COG1660	Displays ATPase and GTPase activities
SLAV_RS03130	COG2124	cytochrome p450
SLAV_RS03135	COG2259	Doxx family
SLAV_RS03185	COG0657	acetylesterase activity
SLAV_RS03195	COG1609	Transcriptional regulator
SLAV_RS03210	COG3250	beta-galactosidase activity
SLAV_RS03235	COG2340	Cysteine-rich secretory protein family
SLAV_RS03250	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLAV_RS03260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLAV_RS03270	COG0667	Aldo Keto reductase
SLAV_RS03325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLAV_RS03365	COG0583	DNA-binding transcription factor activity
SLAV_RS03445	COG0395	ABC-type sugar transport system, permease component
SLAV_RS03485	COG0328	RNA-DNA hybrid ribonuclease activity
SLAV_RS03495	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SLAV_RS03500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLAV_RS03515	COG0668	transmembrane transport
SLAV_RS03545	COG1309	transcriptional regulator
SLAV_RS03580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLAV_RS03600	COG0477	Major facilitator Superfamily
SLAV_RS03630	COG4044	May play a role in the intracellular transport of hydrophobic ligands
SLAV_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS03645	COG1309	transcriptional regulator
SLAV_RS03670	COG1228	amidohydrolase
SLAV_RS03675	COG2132	Multicopper oxidase
SLAV_RS03685	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SLAV_RS03690	COG0477	Major facilitator Superfamily
SLAV_RS03695	COG0009	L-threonylcarbamoyladenylate synthase
SLAV_RS03700	COG3629	intracellular signal transduction
SLAV_RS03700	COG3903	Transcriptional regulator
SLAV_RS03775	COG0583	DNA-binding transcription factor activity
SLAV_RS03780	COG0789	Transcriptional regulator
SLAV_RS03805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLAV_RS03815	COG0747	negative chemotaxis
SLAV_RS03825	COG1309	transcriptional regulator
SLAV_RS03835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS03865	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS03870	COG3979	chitinase
SLAV_RS03875	COG2304	oxidoreductase activity
SLAV_RS03880	COG1278	Cold shock
SLAV_RS03885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLAV_RS03900	COG0789	Transcriptional regulator
SLAV_RS03920	COG4249	Peptidase C14 caspase catalytic subunit p20
SLAV_RS03920	COG2319	Wd-40 repeat
SLAV_RS03965	COG1796	DNA polymerase
SLAV_RS03965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SLAV_RS03995	COG2272	Belongs to the type-B carboxylesterase lipase family
SLAV_RS04060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SLAV_RS04075	COG2197	response regulator
SLAV_RS04080	COG4585	Histidine kinase
SLAV_RS04085	COG2409	Drug exporters of the RND superfamily
SLAV_RS04095	COG4175	Glycine betaine
SLAV_RS04095	COG3448	diguanylate cyclase activity
SLAV_RS04100	COG1191	sigma factor activity
SLAV_RS04110	COG2188	Transcriptional regulator
SLAV_RS04120	COG4264	IucA IucC family
SLAV_RS04125	COG2226	methyltransferase
SLAV_RS04145	COG4585	Histidine kinase
SLAV_RS04150	COG2197	response regulator
SLAV_RS04185	COG1132	(ABC) transporter
SLAV_RS04195	COG0592	DNA-directed DNA polymerase activity
SLAV_RS04215	COG3265	gluconokinase activity
SLAV_RS04240	COG1404	Belongs to the peptidase S8 family
SLAV_RS04240	COG4412	M6 family metalloprotease domain protein
SLAV_RS04240	COG1404	Belongs to the peptidase S8 family
SLAV_RS04240	COG4412	M6 family metalloprotease domain protein
SLAV_RS04245	COG0477	Major facilitator Superfamily
SLAV_RS04265	COG1793	dna ligase
SLAV_RS04275	COG1131	(ABC) transporter
SLAV_RS04290	COG0667	Aldo Keto reductase
SLAV_RS04295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLAV_RS04305	COG1609	Transcriptional regulator
SLAV_RS04310	COG0673	inositol 2-dehydrogenase activity
SLAV_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS04355	COG1120	ATPase activity
SLAV_RS04360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLAV_RS04415	COG1414	Transcriptional regulator
SLAV_RS04430	COG0076	glutamate decarboxylase activity
SLAV_RS04445	COG4565	transcriptional regulatory protein
SLAV_RS04455	COG1301	dicarboxylic acid transport
SLAV_RS04480	COG0596	Alpha beta hydrolase
SLAV_RS04500	COG3511	phospholipase C
SLAV_RS04505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SLAV_RS04525	COG2304	oxidoreductase activity
SLAV_RS04550	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS04555	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS04570	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS04580	COG1024	Enoyl-CoA hydratase
SLAV_RS04605	COG0583	DNA-binding transcription factor activity
SLAV_RS04610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLAV_RS04620	COG2197	response regulator
SLAV_RS04625	COG4585	Histidine kinase
SLAV_RS04635	COG1131	(ABC) transporter
SLAV_RS04645	COG2815	serine threonine protein kinase
SLAV_RS04645	COG0515	serine threonine protein kinase
SLAV_RS04690	COG3864	Putative metallopeptidase domain
SLAV_RS04715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLAV_RS04730	COG0693	protein deglycase activity
SLAV_RS04735	COG2356	endonuclease I
SLAV_RS04750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLAV_RS04755	COG3064	Membrane
SLAV_RS04755	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLAV_RS04755	COG3583	domain protein
SLAV_RS04765	COG2814	Major facilitator Superfamily
SLAV_RS04800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLAV_RS04810	COG4106	trans-aconitate 2-methyltransferase activity
SLAV_RS04815	COG0393	Putative heavy-metal-binding
SLAV_RS04870	COG0702	epimerase
SLAV_RS04890	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS04905	COG1476	TRANSCRIPTIONal
SLAV_RS04930	COG0745	RESPONSE REGULATOR receiver
SLAV_RS04945	COG1132	(ABC) transporter
SLAV_RS04965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLAV_RS04995	COG0515	serine threonine protein kinase
SLAV_RS04995	COG2815	serine threonine protein kinase
SLAV_RS05010	COG0714	Associated with various cellular activities
SLAV_RS05025	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SLAV_RS05090	COG1349	DNA-binding transcription factor activity
SLAV_RS05095	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLAV_RS05145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLAV_RS05165	COG0702	epimerase
SLAV_RS05190	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS05205	COG2326	polyphosphate kinase activity
SLAV_RS05265	COG0148	phosphopyruvate hydratase activity
SLAV_RS05275	COG3415	Transposase
SLAV_RS05275	COG2801	Transposase and inactivated derivatives
SLAV_RS05300	COG2271	Major facilitator Superfamily
SLAV_RS05335	COG1819	glycosyl
SLAV_RS05400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SLAV_RS05410	COG2815	serine threonine protein kinase
SLAV_RS05410	COG0515	serine threonine protein kinase
SLAV_RS05420	COG0586	Pfam SNARE associated Golgi protein
SLAV_RS05425	COG0671	phosphoesterase, PA-phosphatase related
SLAV_RS05460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLAV_RS05465	COG0019	diaminopimelate decarboxylase activity
SLAV_RS05480	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SLAV_RS05485	COG0531	amino acid
SLAV_RS05495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SLAV_RS05500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SLAV_RS05505	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SLAV_RS05595	COG1289	transmembrane transporter activity
SLAV_RS05620	COG0542	response to heat
SLAV_RS05630	COG0484	heat shock protein binding
SLAV_RS05635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SLAV_RS05640	COG0443	Heat shock 70 kDa protein
SLAV_RS05690	COG0494	nUDIX hydrolase
SLAV_RS05900	COG1111	helicase
SLAV_RS05900	COG1205	dead DEAH box helicase
SLAV_RS05915	COG0515	serine threonine protein kinase
SLAV_RS05915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLAV_RS05950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SLAV_RS05965	COG0017	Asparaginyl-tRNA synthetase
SLAV_RS05995	COG2813	Specifically methylates the guanine in position
SLAV_RS06020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLAV_RS06045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLAV_RS06055	COG0183	Belongs to the thiolase family
SLAV_RS06060	COG1609	Transcriptional regulator
SLAV_RS06070	COG0596	Alpha beta hydrolase
SLAV_RS06115	COG3572	ergothioneine biosynthetic process
SLAV_RS06120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLAV_RS06125	COG0121	glutamine amidotransferase
SLAV_RS06130	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SLAV_RS06145	COG2182	Extracellular solute-binding protein
SLAV_RS06150	COG3360	Dodecin
SLAV_RS06160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS06175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SLAV_RS06180	COG1053	succinate dehydrogenase
SLAV_RS06190	COG0583	DNA-binding transcription factor activity
SLAV_RS06200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLAV_RS06240	COG0726	polysaccharide deacetylase
SLAV_RS06245	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SLAV_RS06245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SLAV_RS06295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLAV_RS06315	COG4762	Protein conserved in bacteria
SLAV_RS06370	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SLAV_RS06425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SLAV_RS06495	COG0516	GMP reductase activity
SLAV_RS06495	COG0517	IMP dehydrogenase activity
SLAV_RS06520	COG2770	Histidine kinase
SLAV_RS06520	COG2208	phosphoserine phosphatase activity
SLAV_RS06570	COG1278	Cold shock
SLAV_RS06580	COG0513	Belongs to the DEAD box helicase family
SLAV_RS06625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SLAV_RS06700	COG1902	pentaerythritol trinitrate reductase activity
SLAV_RS06700	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLAV_RS06705	COG2267	carboxylic ester hydrolase activity
SLAV_RS06720	COG0395	ABC-type sugar transport system, permease component
SLAV_RS06725	COG1175	transmembrane transport
SLAV_RS06750	COG0277	FAD linked oxidase domain protein
SLAV_RS06780	COG0589	response to stress
SLAV_RS06795	COG3345	alpha-galactosidase
SLAV_RS06835	COG1024	Enoyl-CoA hydratase
SLAV_RS06850	COG1335	isochorismatase
SLAV_RS06860	COG1366	Belongs to the anti-sigma-factor antagonist family
SLAV_RS06925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SLAV_RS06925	COG0517	IMP dehydrogenase activity
SLAV_RS06925	COG0617	tRNA 3'-terminal CCA addition
SLAV_RS06960	COG0517	IMP dehydrogenase activity
SLAV_RS06960	COG0516	GMP reductase activity
SLAV_RS06970	COG0516	GMP reductase activity
SLAV_RS06970	COG0517	IMP dehydrogenase activity
SLAV_RS06990	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SLAV_RS07000	COG0574	Belongs to the PEP-utilizing enzyme family
SLAV_RS07000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLAV_RS07005	COG0589	response to stress
SLAV_RS07020	COG1063	alcohol dehydrogenase
SLAV_RS07030	COG0516	GMP reductase activity
SLAV_RS07030	COG0517	IMP dehydrogenase activity
SLAV_RS07045	COG0346	lactoylglutathione lyase activity
SLAV_RS07050	COG1556	Lactate utilization protein
SLAV_RS07055	COG1139	Iron-sulfur cluster binding protein
SLAV_RS07060	COG0247	lactate metabolic process
SLAV_RS07070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLAV_RS07095	COG3119	arylsulfatase activity
SLAV_RS07095	COG3119	arylsulfatase activity
SLAV_RS07100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLAV_RS07110	COG2838	Isocitrate dehydrogenase
SLAV_RS07115	COG3152	Membrane
SLAV_RS07120	COG5002	protein histidine kinase activity
SLAV_RS07120	COG5000	phosphorelay sensor kinase activity
SLAV_RS07125	COG0745	RESPONSE REGULATOR receiver
SLAV_RS07160	COG1595	DNA-templated transcription, initiation
SLAV_RS07175	COG2226	methyltransferase
SLAV_RS07185	COG0598	Magnesium transport protein CorA
SLAV_RS07190	COG0583	DNA-binding transcription factor activity
SLAV_RS07235	COG1132	(ABC) transporter
SLAV_RS07280	COG2175	clavaminate synthase activity
SLAV_RS07290	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLAV_RS07315	COG1335	isochorismatase
SLAV_RS07350	COG3959	Transketolase, thiamine diphosphate binding domain
SLAV_RS07355	COG3958	Transketolase
SLAV_RS07390	COG2755	lipolytic protein G-D-S-L family
SLAV_RS07420	COG1657	PFAM Prenyltransferase squalene oxidase
SLAV_RS07430	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLAV_RS07445	COG1562	ergosterol biosynthetic process
SLAV_RS07450	COG1134	teichoic acid transport
SLAV_RS07470	COG0371	Dehydrogenase
SLAV_RS07490	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLAV_RS07500	COG1024	Enoyl-CoA hydratase
SLAV_RS07510	COG4977	sequence-specific DNA binding
SLAV_RS07515	COG0488	(ABC) transporter
SLAV_RS07525	COG0300	oxidoreductase activity
SLAV_RS07540	COG2183	response to ionizing radiation
SLAV_RS07590	COG1022	Amp-dependent synthetase and ligase
SLAV_RS07595	COG0789	Transcriptional regulator
SLAV_RS07605	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLAV_RS07605	COG1024	Enoyl-CoA hydratase
SLAV_RS07610	COG0183	Belongs to the thiolase family
SLAV_RS07615	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS07620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS07625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLAV_RS07635	COG3268	Saccharopine dehydrogenase
SLAV_RS07640	COG1515	deoxyribonuclease V activity
SLAV_RS07665	COG0488	(ABC) transporter
SLAV_RS07695	COG1793	dna ligase
SLAV_RS07705	COG0494	nUDIX hydrolase
SLAV_RS07720	COG1486	melibiose metabolic process
SLAV_RS07765	COG2197	response regulator
SLAV_RS07780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLAV_RS07820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLAV_RS07825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SLAV_RS07865	COG0656	L-ascorbic acid biosynthetic process
SLAV_RS07880	COG2154	pterin-4-alpha-carbinolamine dehydratase
SLAV_RS07915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SLAV_RS07925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLAV_RS07935	COG0531	amino acid
SLAV_RS07995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLAV_RS08015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLAV_RS08020	COG2362	D-Aminopeptidase
SLAV_RS08045	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLAV_RS08055	COG0604	alcohol dehydrogenase
SLAV_RS08060	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLAV_RS08060	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLAV_RS08075	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS08080	COG0688	phosphatidylethanolamine metabolic process
SLAV_RS08095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLAV_RS08110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SLAV_RS08115	COG1929	Belongs to the glycerate kinase type-1 family
SLAV_RS08120	COG1335	isochorismatase
SLAV_RS08160	COG1448	Aminotransferase
SLAV_RS08175	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SLAV_RS08185	COG0483	inositol monophosphate 1-phosphatase activity
SLAV_RS08195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLAV_RS08205	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLAV_RS08250	COG0604	alcohol dehydrogenase
SLAV_RS08250	COG3321	synthase
SLAV_RS08255	COG3321	synthase
SLAV_RS08255	COG0604	alcohol dehydrogenase
SLAV_RS08285	COG3321	synthase
SLAV_RS08285	COG0604	alcohol dehydrogenase
SLAV_RS08310	COG4585	Histidine kinase
SLAV_RS08315	COG2197	response regulator
SLAV_RS08330	COG0435	Glutathione S-transferase
SLAV_RS08390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLAV_RS08395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLAV_RS08420	COG0405	Gamma-glutamyltransferase
SLAV_RS08440	COG2205	protein histidine kinase activity
SLAV_RS08445	COG0745	RESPONSE REGULATOR receiver
SLAV_RS08455	COG1376	ErfK ybiS ycfS ynhG family protein
SLAV_RS08465	COG0765	amino acid transport
SLAV_RS08470	COG0765	amino acid transport
SLAV_RS08475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLAV_RS08480	COG1126	abc transporter atp-binding protein
SLAV_RS08505	COG1940	carbohydrate kinase activity
SLAV_RS08510	COG1129	ABC transporter
SLAV_RS08525	COG0673	inositol 2-dehydrogenase activity
SLAV_RS08540	COG4266	Belongs to the allantoicase family
SLAV_RS08545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLAV_RS08550	COG1414	Transcriptional regulator
SLAV_RS08560	COG1136	(ABC) transporter
SLAV_RS08570	COG4585	Histidine kinase
SLAV_RS08575	COG2197	response regulator
SLAV_RS08595	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SLAV_RS08625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLAV_RS08630	COG2233	PERMEase
SLAV_RS08645	COG2351	hydroxyisourate hydrolase activity
SLAV_RS08665	COG3622	Belongs to the hyi family
SLAV_RS08670	COG2084	Dehydrogenase
SLAV_RS08675	COG0753	catalase activity
SLAV_RS08685	COG3960	tartronate-semialdehyde synthase activity
SLAV_RS08695	COG0386	Belongs to the glutathione peroxidase family
SLAV_RS08715	COG0464	growth
SLAV_RS08755	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS08765	COG0598	Magnesium transport protein CorA
SLAV_RS08805	COG2124	cytochrome p450
SLAV_RS08815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLAV_RS08860	COG0308	aminopeptidase N
SLAV_RS08865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS08885	COG1937	Protein conserved in bacteria
SLAV_RS08910	COG4555	ABC transporter
SLAV_RS08930	COG0574	Belongs to the PEP-utilizing enzyme family
SLAV_RS08930	COG3848	Pyruvate phosphate dikinase
SLAV_RS08975	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS08980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLAV_RS08980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLAV_RS09010	COG1410	methionine synthase
SLAV_RS09010	COG0646	methionine synthase
SLAV_RS09015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLAV_RS09020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLAV_RS09040	COG4106	trans-aconitate 2-methyltransferase activity
SLAV_RS09065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLAV_RS09095	COG3903	Transcriptional regulator
SLAV_RS09095	COG3629	intracellular signal transduction
SLAV_RS09115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS09130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS09145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS09165	COG0017	Asparaginyl-tRNA synthetase
SLAV_RS09170	COG0069	glutamate synthase activity
SLAV_RS09210	COG2197	response regulator
SLAV_RS09305	COG4552	Acetyltransferase involved in intracellular survival and related
SLAV_RS09320	COG2252	PERMEase
SLAV_RS09325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLAV_RS09340	COG3835	regulator
SLAV_RS09350	COG1802	Transcriptional regulator
SLAV_RS09370	COG0028	Belongs to the TPP enzyme family
SLAV_RS09380	COG1404	Belongs to the peptidase S8 family
SLAV_RS09395	COG1162	GTPase activity
SLAV_RS09415	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS09425	COG0456	acetyltransferase
SLAV_RS09425	COG1846	Transcriptional regulator
SLAV_RS09440	COG0175	sulfate reduction
SLAV_RS09445	COG0529	Catalyzes the synthesis of activated sulfate
SLAV_RS09470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLAV_RS09485	COG0667	Aldo Keto reductase
SLAV_RS09500	COG0604	alcohol dehydrogenase
SLAV_RS09600	COG0583	DNA-binding transcription factor activity
SLAV_RS09605	COG0504	CTP synthase activity
SLAV_RS09630	COG3511	phospholipase C
SLAV_RS09640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLAV_RS09645	COG1216	Glycosyl transferase, family 2
SLAV_RS09650	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS09655	COG0463	Glycosyl transferase, family 2
SLAV_RS09670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLAV_RS09675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SLAV_RS09725	COG3220	belongs to the UPF0276 family
SLAV_RS09735	COG0596	Alpha beta hydrolase
SLAV_RS09740	COG3253	May function as heme-dependent peroxidase
SLAV_RS09745	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLAV_RS09755	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLAV_RS09760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SLAV_RS09785	COG0183	Belongs to the thiolase family
SLAV_RS09790	COG1024	Enoyl-CoA hydratase
SLAV_RS09790	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLAV_RS09800	COG1216	Glycosyl transferase, family 2
SLAV_RS09800	COG0463	Glycosyl transferase, family 2
SLAV_RS09810	COG1083	cytidylyl-transferase
SLAV_RS09815	COG2089	acid synthase
SLAV_RS09830	COG1316	TRANSCRIPTIONal
SLAV_RS09835	COG0531	amino acid
SLAV_RS09840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLAV_RS09845	COG4214	carbohydrate transport
SLAV_RS09855	COG4213	ABC transporter substrate-binding protein
SLAV_RS09860	COG1940	carbohydrate kinase activity
SLAV_RS09870	COG1285	pathogenesis
SLAV_RS09875	COG0395	ABC-type sugar transport system, permease component
SLAV_RS09880	COG1175	transmembrane transport
SLAV_RS09885	COG1653	transport
SLAV_RS09890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SLAV_RS09895	COG1609	Transcriptional regulator
SLAV_RS09905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLAV_RS09940	COG4608	Belongs to the ABC transporter superfamily
SLAV_RS09955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLAV_RS09985	COG3938	Belongs to the proline racemase family
SLAV_RS10015	COG0006	proline dipeptidase activity
SLAV_RS10025	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS10050	COG1024	Enoyl-CoA hydratase
SLAV_RS10060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SLAV_RS10075	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SLAV_RS10085	COG2040	homocysteine
SLAV_RS10115	COG1799	cell septum assembly
SLAV_RS10135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS10140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLAV_RS10155	COG0431	NADPH-dependent FMN reductase
SLAV_RS10190	COG0252	asparaginase activity
SLAV_RS10200	COG3903	Transcriptional regulator
SLAV_RS10200	COG3629	intracellular signal transduction
SLAV_RS10210	COG1136	(ABC) transporter
SLAV_RS10210	COG0577	efflux transmembrane transporter activity
SLAV_RS10245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SLAV_RS10265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS10290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLAV_RS10310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLAV_RS10325	COG0475	glutathione-regulated potassium exporter activity
SLAV_RS10335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SLAV_RS10340	COG0531	amino acid
SLAV_RS10345	COG0569	domain protein
SLAV_RS10380	COG0756	dUTP diphosphatase activity
SLAV_RS10405	COG2205	protein histidine kinase activity
SLAV_RS10410	COG0745	RESPONSE REGULATOR receiver
SLAV_RS10420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SLAV_RS10500	COG1309	transcriptional regulator
SLAV_RS10505	COG1435	thymidine kinase activity
SLAV_RS10520	COG0045	succinate-CoA ligase (ADP-forming) activity
SLAV_RS10520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLAV_RS10520	COG1042	CoA-binding domain protein
SLAV_RS10525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLAV_RS10530	COG1802	Transcriptional regulator
SLAV_RS10545	COG0612	Peptidase, M16
SLAV_RS10550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLAV_RS10570	COG0372	Belongs to the citrate synthase family
SLAV_RS10580	COG1672	PFAM Archaeal ATPase
SLAV_RS10580	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLAV_RS10600	COG3290	protein histidine kinase activity
SLAV_RS10605	COG4565	transcriptional regulatory protein
SLAV_RS10610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLAV_RS10635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLAV_RS10645	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SLAV_RS10680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SLAV_RS10725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SLAV_RS10730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SLAV_RS10735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SLAV_RS10770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SLAV_RS10780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLAV_RS10785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SLAV_RS10795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SLAV_RS10815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLAV_RS10825	COG0583	DNA-binding transcription factor activity
SLAV_RS10840	COG1609	Transcriptional regulator
SLAV_RS10860	COG2205	protein histidine kinase activity
SLAV_RS10865	COG0745	RESPONSE REGULATOR receiver
SLAV_RS10870	COG1126	abc transporter atp-binding protein
SLAV_RS10875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLAV_RS10880	COG0765	amino acid transport
SLAV_RS10885	COG0765	amino acid transport
SLAV_RS10890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLAV_RS10910	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SLAV_RS10930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLAV_RS10985	COG1201	RNA secondary structure unwinding
SLAV_RS10995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLAV_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS11010	COG1396	sequence-specific DNA binding
SLAV_RS11015	COG1546	Belongs to the CinA family
SLAV_RS11015	COG1058	Belongs to the CinA family
SLAV_RS11025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLAV_RS11035	COG1674	ftsk spoiiie
SLAV_RS11045	COG3437	response regulator, receiver
SLAV_RS11045	COG2205	protein histidine kinase activity
SLAV_RS11045	COG4999	Histidine kinase
SLAV_RS11045	COG3850	Histidine kinase
SLAV_RS11050	COG2208	phosphoserine phosphatase activity
SLAV_RS11050	COG2770	Histidine kinase
SLAV_RS11080	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SLAV_RS11085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLAV_RS11090	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SLAV_RS11110	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SLAV_RS11115	COG0612	Peptidase, M16
SLAV_RS11120	COG1185	polyribonucleotide nucleotidyltransferase activity
SLAV_RS11125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SLAV_RS11135	COG1674	ftsk spoiiie
SLAV_RS11155	COG1404	Belongs to the peptidase S8 family
SLAV_RS11160	COG3266	domain, Protein
SLAV_RS11175	COG0455	bacterial-type flagellum organization
SLAV_RS11190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SLAV_RS11195	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SLAV_RS11205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SLAV_RS11220	COG0779	Required for maturation of 30S ribosomal subunits
SLAV_RS11245	COG0442	prolyl-tRNA aminoacylation
SLAV_RS11260	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLAV_RS11265	COG0750	zinc metalloprotease
SLAV_RS11270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SLAV_RS11285	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS11290	COG2508	Transcriptional regulator
SLAV_RS11320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLAV_RS11325	COG1177	transmembrane transport
SLAV_RS11330	COG1176	ABC-type spermidine putrescine transport system, permease component I
SLAV_RS11335	COG3842	ATPase activity
SLAV_RS11340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SLAV_RS11345	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS11355	COG1051	belongs to the nudix hydrolase family
SLAV_RS11365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLAV_RS11375	COG4585	Histidine kinase
SLAV_RS11380	COG2197	response regulator
SLAV_RS11395	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS11405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLAV_RS11410	COG1136	(ABC) transporter
SLAV_RS11450	COG3842	ATPase activity
SLAV_RS11465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SLAV_RS11470	COG0575	Belongs to the CDS family
SLAV_RS11475	COG0233	cytoplasmic translational termination
SLAV_RS11480	COG0528	UMP kinase activity
SLAV_RS11485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SLAV_RS11490	COG0052	Belongs to the universal ribosomal protein uS2 family
SLAV_RS11505	COG1191	sigma factor activity
SLAV_RS11520	COG0792	nuclease activity
SLAV_RS11545	COG0681	Belongs to the peptidase S26 family
SLAV_RS11550	COG0681	Belongs to the peptidase S26 family
SLAV_RS11555	COG0335	large ribosomal subunit rRNA binding
SLAV_RS11560	COG0336	Belongs to the RNA methyltransferase TrmD family
SLAV_RS11565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SLAV_RS11570	COG1837	Belongs to the UPF0109 family
SLAV_RS11575	COG0228	four-way junction DNA binding
SLAV_RS11585	COG0442	prolyl-tRNA aminoacylation
SLAV_RS11595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLAV_RS11605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SLAV_RS11635	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SLAV_RS11645	COG0477	Major facilitator Superfamily
SLAV_RS11650	COG1196	nuclear chromosome segregation
SLAV_RS11665	COG1254	Belongs to the acylphosphatase family
SLAV_RS11670	COG2340	Cysteine-rich secretory protein family
SLAV_RS11675	COG0655	NAD(P)H dehydrogenase (quinone) activity
SLAV_RS11680	COG1733	regulation of RNA biosynthetic process
SLAV_RS11685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLAV_RS11690	COG0571	ribonuclease III activity
SLAV_RS11695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SLAV_RS11710	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SLAV_RS11715	COG0742	ribosomal rna small subunit methyltransferase
SLAV_RS11720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SLAV_RS11725	COG1461	Dihydroxyacetone kinase
SLAV_RS11730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLAV_RS11735	COG0351	phosphomethylpyrimidine kinase
SLAV_RS11755	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLAV_RS11760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SLAV_RS11770	COG1920	GTP binding
SLAV_RS11775	COG0776	regulation of translation
SLAV_RS11785	COG0066	3-isopropylmalate dehydratase activity
SLAV_RS11790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SLAV_RS11825	COG1011	Hydrolase
SLAV_RS11835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SLAV_RS11840	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLAV_RS11850	COG5002	protein histidine kinase activity
SLAV_RS11855	COG2018	Roadblock/LC7 domain
SLAV_RS11875	COG2018	Roadblock/LC7 domain
SLAV_RS11915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLAV_RS11920	COG2353	YceI-like domain
SLAV_RS11930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLAV_RS11945	COG2957	Belongs to the agmatine deiminase family
SLAV_RS11950	COG0804	urea catabolic process
SLAV_RS11955	COG0831	urea catabolic process
SLAV_RS11955	COG0832	Belongs to the urease beta subunit family
SLAV_RS11965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SLAV_RS11970	COG0473	3-isopropylmalate dehydrogenase activity
SLAV_RS11975	COG0583	DNA-binding transcription factor activity
SLAV_RS11980	COG2130	NADP-dependent
SLAV_RS11985	COG3511	phospholipase C
SLAV_RS12015	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS12020	COG0506	proline dehydrogenase activity
SLAV_RS12025	COG3835	regulator
SLAV_RS12035	COG0477	Major facilitator Superfamily
SLAV_RS12040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLAV_RS12045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SLAV_RS12050	COG0440	acetolactate synthase activity
SLAV_RS12070	COG0667	Aldo Keto reductase
SLAV_RS12075	COG2133	pyrroloquinoline quinone binding
SLAV_RS12085	COG2197	response regulator
SLAV_RS12095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLAV_RS12100	COG2409	Drug exporters of the RND superfamily
SLAV_RS12115	COG2318	DinB family
SLAV_RS12135	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLAV_RS12145	COG0154	amidase activity
SLAV_RS12150	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLAV_RS12160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLAV_RS12185	COG3321	synthase
SLAV_RS12185	COG0604	alcohol dehydrogenase
SLAV_RS12185	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS12190	COG0482	sulfurtransferase activity
SLAV_RS12210	COG2860	membrane
SLAV_RS12215	COG4608	Belongs to the ABC transporter superfamily
SLAV_RS12220	COG0444	Belongs to the ABC transporter superfamily
SLAV_RS12225	COG0601	transmembrane transport
SLAV_RS12235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLAV_RS12255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLAV_RS12260	COG0509	glycine decarboxylation via glycine cleavage system
SLAV_RS12265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLAV_RS12275	COG1760	l-serine dehydratase
SLAV_RS12300	COG0310	cobalt ion transport
SLAV_RS12305	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
SLAV_RS12315	COG1122	ATPase activity
SLAV_RS12395	COG0297	glycogen (starch) synthase activity
SLAV_RS12400	COG0489	protein tyrosine kinase activity
SLAV_RS12440	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SLAV_RS12445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLAV_RS12450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SLAV_RS12475	COG0058	SHG alpha-glucan phosphorylase activity
SLAV_RS12495	COG0366	Alpha amylase catalytic
SLAV_RS12500	COG0366	Alpha amylase catalytic
SLAV_RS12515	COG3118	belongs to the thioredoxin family
SLAV_RS12530	COG0205	6-phosphofructokinase activity
SLAV_RS12535	COG0280	phosphate acetyltransferase
SLAV_RS12535	COG0857	belongs to the CobB CobQ family
SLAV_RS12540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SLAV_RS12580	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLAV_RS12580	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLAV_RS12645	COG0183	Belongs to the thiolase family
SLAV_RS12665	COG1131	(ABC) transporter
SLAV_RS12700	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SLAV_RS12715	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLAV_RS12730	COG4585	Histidine kinase
SLAV_RS12735	COG2197	response regulator
SLAV_RS12750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SLAV_RS12755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SLAV_RS12760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SLAV_RS12765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SLAV_RS12770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLAV_RS12775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SLAV_RS12780	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLAV_RS12800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLAV_RS12805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLAV_RS12815	COG2890	protein-(glutamine-N5) methyltransferase activity
SLAV_RS12820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SLAV_RS12825	COG0254	rRNA binding
SLAV_RS12840	COG0083	homoserine kinase activity
SLAV_RS12845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SLAV_RS12850	COG0460	homoserine dehydrogenase
SLAV_RS12855	COG0019	diaminopimelate decarboxylase activity
SLAV_RS12860	COG0018	arginyl-trna synthetase
SLAV_RS12865	COG0745	RESPONSE REGULATOR receiver
SLAV_RS12895	COG3608	succinylglutamate desuccinylase aspartoacylase
SLAV_RS12895	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SLAV_RS12910	COG1793	dna ligase
SLAV_RS12910	COG3285	dna ligase
SLAV_RS12915	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SLAV_RS12935	COG2205	protein histidine kinase activity
SLAV_RS12945	COG1309	transcriptional regulator
SLAV_RS12985	COG3883	PFAM NLP P60 protein
SLAV_RS12985	COG0791	NLP P60 protein
SLAV_RS13010	COG5002	protein histidine kinase activity
SLAV_RS13025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SLAV_RS13040	COG2897	thiosulfate sulfurtransferase activity
SLAV_RS13055	COG0745	RESPONSE REGULATOR receiver
SLAV_RS13060	COG2205	protein histidine kinase activity
SLAV_RS13065	COG0567	Dehydrogenase, E1 component
SLAV_RS13065	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLAV_RS13130	COG4106	trans-aconitate 2-methyltransferase activity
SLAV_RS13135	COG1126	abc transporter atp-binding protein
SLAV_RS13140	COG0765	amino acid transport
SLAV_RS13145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLAV_RS13155	COG0604	alcohol dehydrogenase
SLAV_RS13185	COG5640	endopeptidase activity
SLAV_RS13205	COG0142	geranyltranstransferase activity
SLAV_RS13210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLAV_RS13215	COG1959	2 iron, 2 sulfur cluster binding
SLAV_RS13220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLAV_RS13220	COG1017	nitric oxide dioxygenase activity
SLAV_RS13235	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SLAV_RS13280	COG1309	transcriptional regulator
SLAV_RS13285	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS13290	COG0363	glucosamine-6-phosphate deaminase activity
SLAV_RS13295	COG1472	Belongs to the glycosyl hydrolase 3 family
SLAV_RS13300	COG0395	ABC-type sugar transport system, permease component
SLAV_RS13305	COG1175	transmembrane transport
SLAV_RS13310	COG2182	Extracellular solute-binding protein
SLAV_RS13315	COG2188	Transcriptional regulator
SLAV_RS13320	COG1966	Carbon starvation protein
SLAV_RS13350	COG0242	peptide deformylase activity
SLAV_RS13365	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SLAV_RS13365	COG2199	diguanylate cyclase activity
SLAV_RS13370	COG5662	AntiSigma factor
SLAV_RS13375	COG1595	DNA-templated transcription, initiation
SLAV_RS13385	COG2135	peptidase activity
SLAV_RS13395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SLAV_RS13405	COG2076	Multidrug Resistance protein
SLAV_RS13415	COG0483	inositol monophosphate 1-phosphatase activity
SLAV_RS13425	COG0753	catalase activity
SLAV_RS13450	COG1615	UPF0182 protein
SLAV_RS13460	COG3480	Lon protease (S16) C-terminal proteolytic domain
SLAV_RS13515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SLAV_RS13560	COG0210	DNA helicase
SLAV_RS13580	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLAV_RS13620	COG0601	transmembrane transport
SLAV_RS13625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLAV_RS13670	COG0513	Belongs to the DEAD box helicase family
SLAV_RS13675	COG0596	Alpha beta hydrolase
SLAV_RS13680	COG2095	MarC family integral membrane protein
SLAV_RS13700	COG0598	Magnesium transport protein CorA
SLAV_RS13735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLAV_RS13740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLAV_RS13750	COG1595	DNA-templated transcription, initiation
SLAV_RS13765	COG1024	Enoyl-CoA hydratase
SLAV_RS13770	COG0519	Catalyzes the synthesis of GMP from XMP
SLAV_RS13785	COG1611	Belongs to the LOG family
SLAV_RS13790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLAV_RS13825	COG2197	response regulator
SLAV_RS13830	COG4585	Histidine kinase
SLAV_RS13840	COG1131	(ABC) transporter
SLAV_RS13860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLAV_RS13870	COG4608	Belongs to the ABC transporter superfamily
SLAV_RS13875	COG0444	Belongs to the ABC transporter superfamily
SLAV_RS13880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLAV_RS13890	COG4166	transmembrane transport
SLAV_RS13900	COG4608	Belongs to the ABC transporter superfamily
SLAV_RS13910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLAV_RS13920	COG0747	negative chemotaxis
SLAV_RS13925	COG1217	gtp-binding protein TYPA
SLAV_RS13945	COG1053	succinate dehydrogenase
SLAV_RS13955	COG0515	serine threonine protein kinase
SLAV_RS13955	COG2815	serine threonine protein kinase
SLAV_RS13965	COG1842	Phage shock protein A
SLAV_RS14020	COG0697	spore germination
SLAV_RS14115	COG0012	GTP binding
SLAV_RS14130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SLAV_RS14145	COG1722	exodeoxyribonuclease VII activity
SLAV_RS14150	COG0778	Nitroreductase
SLAV_RS14175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SLAV_RS14175	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SLAV_RS14200	COG0114	fumarate hydratase activity
SLAV_RS14215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLAV_RS14215	COG4499	WXG100 protein secretion system (Wss), protein YukC
SLAV_RS14235	COG0450	alkyl hydroperoxide reductase
SLAV_RS14240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLAV_RS14260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SLAV_RS14265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLAV_RS14270	COG0667	Aldo Keto reductase
SLAV_RS14310	COG0726	polysaccharide deacetylase
SLAV_RS14360	COG1309	transcriptional regulator
SLAV_RS14365	COG2885	chlorophyll binding
SLAV_RS14385	COG2197	response regulator
SLAV_RS14390	COG4585	Histidine kinase
SLAV_RS14420	COG2894	cell division
SLAV_RS14450	COG1414	Transcriptional regulator
SLAV_RS14460	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SLAV_RS14570	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SLAV_RS14590	COG0463	Glycosyl transferase, family 2
SLAV_RS14605	COG1331	Highly conserved protein containing a thioredoxin domain
SLAV_RS14620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLAV_RS14635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SLAV_RS14645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SLAV_RS14675	COG0501	Belongs to the peptidase M48B family
SLAV_RS14685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLAV_RS14695	COG3119	arylsulfatase activity
SLAV_RS14700	COG1064	alcohol dehydrogenase
SLAV_RS14715	COG1136	(ABC) transporter
SLAV_RS14725	COG1376	ErfK ybiS ycfS ynhG family protein
SLAV_RS14740	COG2986	histidine ammonia-lyase
SLAV_RS14750	COG1024	Enoyl-CoA hydratase
SLAV_RS14755	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLAV_RS14765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLAV_RS14775	COG0424	maF-like protein
SLAV_RS14785	COG4770	biotin carboxylase activity
SLAV_RS14810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLAV_RS14820	COG2205	protein histidine kinase activity
SLAV_RS14825	COG0745	RESPONSE REGULATOR receiver
SLAV_RS14830	COG1595	DNA-templated transcription, initiation
SLAV_RS14845	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS14850	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS14885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLAV_RS14905	COG0151	Belongs to the GarS family
SLAV_RS14920	COG0583	DNA-binding transcription factor activity
SLAV_RS14925	COG2814	Major facilitator Superfamily
SLAV_RS14960	COG1079	Belongs to the binding-protein-dependent transport system permease family
SLAV_RS14970	COG3845	ABC transporter
SLAV_RS14975	COG1744	ABC transporter substrate-binding protein PnrA-like
SLAV_RS14980	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLAV_RS14980	COG1473	amidohydrolase
SLAV_RS14990	COG2089	acid synthase
SLAV_RS15000	COG1216	Glycosyl transferase, family 2
SLAV_RS15015	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLAV_RS15015	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLAV_RS15030	COG1595	DNA-templated transcription, initiation
SLAV_RS15040	COG2009	succinate dehydrogenase
SLAV_RS15050	COG1053	succinate dehydrogenase
SLAV_RS15055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SLAV_RS15065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLAV_RS15090	COG1309	transcriptional regulator
SLAV_RS15100	COG1846	Transcriptional regulator
SLAV_RS15110	COG1408	metallophosphoesterase
SLAV_RS15120	COG1686	Belongs to the peptidase S11 family
SLAV_RS15125	COG1295	ribonuclease BN
SLAV_RS15135	COG0180	Tryptophanyl-tRNA synthetase
SLAV_RS15140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLAV_RS15145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLAV_RS15150	COG0754	glutathionylspermidine amidase activity
SLAV_RS15165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLAV_RS15170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLAV_RS15190	COG0039	L-malate dehydrogenase activity
SLAV_RS15210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SLAV_RS15220	COG0138	bifunctional purine biosynthesis protein purh
SLAV_RS15255	COG0045	succinate-CoA ligase (ADP-forming) activity
SLAV_RS15260	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SLAV_RS15270	COG0714	Associated with various cellular activities
SLAV_RS15290	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLAV_RS15315	COG0640	Transcriptional regulator
SLAV_RS15330	COG2382	esterase
SLAV_RS15330	COG3693	PFAM glycoside hydrolase, family 10
SLAV_RS15335	COG2197	response regulator
SLAV_RS15370	COG0519	Catalyzes the synthesis of GMP from XMP
SLAV_RS15370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SLAV_RS15390	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS15395	COG0515	serine threonine protein kinase
SLAV_RS15405	COG0515	serine threonine protein kinase
SLAV_RS15405	COG2815	serine threonine protein kinase
SLAV_RS15435	COG0516	GMP reductase activity
SLAV_RS15445	COG1595	DNA-templated transcription, initiation
SLAV_RS15450	COG2197	response regulator
SLAV_RS15460	COG0583	DNA-binding transcription factor activity
SLAV_RS15465	COG4221	oxidoreductase activity
SLAV_RS15480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SLAV_RS15490	COG0745	RESPONSE REGULATOR receiver
SLAV_RS15495	COG2205	protein histidine kinase activity
SLAV_RS15500	COG1316	TRANSCRIPTIONal
SLAV_RS15520	COG0726	polysaccharide deacetylase
SLAV_RS15525	COG0726	polysaccharide deacetylase
SLAV_RS15545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SLAV_RS15565	COG0802	atpase or kinase
SLAV_RS15575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SLAV_RS15585	COG0736	holo-[acyl-carrier-protein] synthase activity
SLAV_RS15590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLAV_RS15600	COG1072	(Pantothenic acid kinase))
SLAV_RS15610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLAV_RS15615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SLAV_RS15620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SLAV_RS15630	COG0488	(ABC) transporter
SLAV_RS15635	COG0101	tRNA pseudouridine synthase activity
SLAV_RS15640	COG0203	ribosomal protein L17
SLAV_RS15645	COG0202	RNA polymerase activity
SLAV_RS15650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SLAV_RS15655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SLAV_RS15660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SLAV_RS15665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SLAV_RS15675	COG0563	adenylate kinase activity
SLAV_RS15680	COG0201	protein transport
SLAV_RS15685	COG0200	Binds to the 23S rRNA
SLAV_RS15690	COG1841	ribosomal large subunit assembly
SLAV_RS15695	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SLAV_RS15700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SLAV_RS15705	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SLAV_RS15710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SLAV_RS15720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLAV_RS15725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SLAV_RS15730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SLAV_RS15735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SLAV_RS15740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SLAV_RS15745	COG0255	Belongs to the universal ribosomal protein uL29 family
SLAV_RS15750	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SLAV_RS15755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SLAV_RS15760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SLAV_RS15765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SLAV_RS15770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SLAV_RS15775	COG0089	rRNA binding
SLAV_RS15780	COG0088	Forms part of the polypeptide exit tunnel
SLAV_RS15785	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SLAV_RS15790	COG0051	transcription antitermination factor activity, RNA binding
SLAV_RS15800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLAV_RS15805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLAV_RS15810	COG0049	tRNA binding
SLAV_RS15815	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SLAV_RS15825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLAV_RS15850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SLAV_RS15855	COG0085	RNA polymerase activity
SLAV_RS15865	COG0222	ribosome binding
SLAV_RS15870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SLAV_RS15900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SLAV_RS15910	COG0436	Aminotransferase
SLAV_RS15915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLAV_RS15925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SLAV_RS15935	COG0477	Major facilitator Superfamily
SLAV_RS15955	COG2030	dehydratase
SLAV_RS15960	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLAV_RS15980	COG0702	epimerase
SLAV_RS16000	COG1666	GTP binding
SLAV_RS16015	COG3304	Inner membrane component domain
SLAV_RS16020	COG0501	Belongs to the peptidase M48B family
SLAV_RS16025	COG1007	ATP synthesis coupled electron transport
SLAV_RS16040	COG0713	ATP synthesis coupled electron transport
SLAV_RS16045	COG0839	Belongs to the complex I subunit 6 family
SLAV_RS16050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLAV_RS16055	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLAV_RS16060	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLAV_RS16065	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLAV_RS16070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLAV_RS16090	COG0674	pyruvate-flavodoxin oxidoreductase activity
SLAV_RS16090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SLAV_RS16095	COG1013	pyruvate-flavodoxin oxidoreductase activity
SLAV_RS16100	COG1733	regulation of RNA biosynthetic process
SLAV_RS16105	COG0702	epimerase
SLAV_RS16135	COG0142	geranyltranstransferase activity
SLAV_RS16140	COG3104	oligopeptide transport
SLAV_RS16145	COG2936	dipeptidyl-peptidase activity
SLAV_RS16175	COG0561	phosphatase activity
SLAV_RS16200	COG1007	ATP synthesis coupled electron transport
SLAV_RS16210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLAV_RS16215	COG0713	ATP synthesis coupled electron transport
SLAV_RS16220	COG0839	Belongs to the complex I subunit 6 family
SLAV_RS16225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLAV_RS16230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLAV_RS16235	COG1034	ATP synthesis coupled electron transport
SLAV_RS16240	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLAV_RS16250	COG0649	NAD binding
SLAV_RS16255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLAV_RS16260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLAV_RS16270	COG0791	NLP P60 protein
SLAV_RS16290	COG2066	Belongs to the glutaminase family
SLAV_RS16295	COG2226	methyltransferase
SLAV_RS16310	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLAV_RS16325	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLAV_RS16330	COG1278	Cold shock
SLAV_RS16345	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS16350	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLAV_RS16355	COG2365	Tyrosine phosphatase family
SLAV_RS16390	COG0346	lactoylglutathione lyase activity
SLAV_RS16440	COG2205	protein histidine kinase activity
SLAV_RS16445	COG0745	RESPONSE REGULATOR receiver
SLAV_RS16460	COG0577	efflux transmembrane transporter activity
SLAV_RS16460	COG1136	(ABC) transporter
SLAV_RS16465	COG0577	efflux transmembrane transporter activity
SLAV_RS16465	COG1136	(ABC) transporter
SLAV_RS16475	COG0494	nUDIX hydrolase
SLAV_RS16500	COG1819	glycosyl
SLAV_RS16565	COG1024	Enoyl-CoA hydratase
SLAV_RS16585	COG2188	Transcriptional regulator
SLAV_RS16600	COG0515	serine threonine protein kinase
SLAV_RS16600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLAV_RS16615	COG1309	transcriptional regulator
SLAV_RS16625	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS16630	COG0183	Belongs to the thiolase family
SLAV_RS16640	COG0384	phenazine biosynthesis protein PhzF
SLAV_RS16670	COG2072	flavoprotein involved in K transport
SLAV_RS16680	COG1024	Enoyl-CoA hydratase
SLAV_RS16705	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SLAV_RS16710	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS16715	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS16800	COG0640	Transcriptional regulator
SLAV_RS16830	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS16835	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS16845	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS16860	COG1652	LysM domain
SLAV_RS16910	COG1131	(ABC) transporter
SLAV_RS16985	COG2207	Transcriptional regulator
SLAV_RS16985	COG3708	Transcriptional regulator
SLAV_RS17005	COG4821	SIS domain
SLAV_RS17025	COG0259	pyridoxamine-phosphate oxidase activity
SLAV_RS17055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLAV_RS17095	COG0277	FAD linked oxidase domain protein
SLAV_RS17095	COG0247	lactate metabolic process
SLAV_RS17100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SLAV_RS17120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLAV_RS17125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLAV_RS17135	COG2252	PERMEase
SLAV_RS17160	COG1834	amidinotransferase
SLAV_RS17165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SLAV_RS17175	COG0667	Aldo Keto reductase
SLAV_RS17195	COG2268	Band 7 protein
SLAV_RS17220	COG2814	Major facilitator Superfamily
SLAV_RS17230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SLAV_RS17235	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLAV_RS17240	COG1278	Cold shock
SLAV_RS17270	COG1061	Type III restriction enzyme res subunit
SLAV_RS17285	COG3973	AAA domain
SLAV_RS17315	COG1737	Transcriptional regulator
SLAV_RS17320	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SLAV_RS17340	COG0135	phosphoribosylanthranilate isomerase activity
SLAV_RS17370	COG0463	Glycosyl transferase, family 2
SLAV_RS17390	COG0561	phosphatase activity
SLAV_RS17390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLAV_RS17410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SLAV_RS17435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SLAV_RS17460	COG3290	protein histidine kinase activity
SLAV_RS17515	COG3842	ATPase activity
SLAV_RS17525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SLAV_RS17535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SLAV_RS17540	COG0215	cysteine-tRNA ligase activity
SLAV_RS17545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SLAV_RS17550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SLAV_RS17555	COG1329	Transcriptional regulator
SLAV_RS17575	COG5002	protein histidine kinase activity
SLAV_RS17590	COG0588	phosphoglycerate mutase activity
SLAV_RS17605	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS17650	COG1733	regulation of RNA biosynthetic process
SLAV_RS17665	COG1595	DNA-templated transcription, initiation
SLAV_RS17675	COG2890	protein-(glutamine-N5) methyltransferase activity
SLAV_RS17680	COG4552	Acetyltransferase involved in intracellular survival and related
SLAV_RS17690	COG1490	D-aminoacyl-tRNA deacylase activity
SLAV_RS17700	COG0735	belongs to the Fur family
SLAV_RS17705	COG3485	protocatechuate 3,4-dioxygenase
SLAV_RS17745	COG0745	RESPONSE REGULATOR receiver
SLAV_RS17750	COG1609	Transcriptional regulator
SLAV_RS17755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLAV_RS17770	COG0823	Involved in the tonB-independent uptake of proteins
SLAV_RS17775	COG1309	transcriptional regulator
SLAV_RS17780	COG0596	Alpha beta hydrolase
SLAV_RS17785	COG0737	Belongs to the 5'-nucleotidase family
SLAV_RS17790	COG0456	acetyltransferase
SLAV_RS17820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SLAV_RS17825	COG0306	phosphate transporter
SLAV_RS17835	COG1937	Protein conserved in bacteria
SLAV_RS17850	COG0671	phosphoesterase, PA-phosphatase related
SLAV_RS17870	COG1280	lysine exporter protein (LysE YggA)
SLAV_RS17875	COG1357	PFAM Pentapeptide repeats (8 copies)
SLAV_RS18000	COG1252	NADH dehydrogenase
SLAV_RS18020	COG0579	oxidoreductase
SLAV_RS18035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SLAV_RS18050	COG0741	lytic transglycosylase activity
SLAV_RS18050	COG0739	heme binding
SLAV_RS18050	COG1196	nuclear chromosome segregation
SLAV_RS18070	COG0513	Belongs to the DEAD box helicase family
SLAV_RS18080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLAV_RS18085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLAV_RS18110	COG0785	Cytochrome C biogenesis protein
SLAV_RS18125	COG1643	Atp-dependent helicase
SLAV_RS18155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SLAV_RS18170	COG3119	arylsulfatase activity
SLAV_RS18190	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLAV_RS18195	COG0047	phosphoribosylformylglycinamidine synthase activity
SLAV_RS18200	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLAV_RS18225	COG2197	response regulator
SLAV_RS18235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SLAV_RS18250	COG0151	Belongs to the GarS family
SLAV_RS18280	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SLAV_RS18290	COG1349	DNA-binding transcription factor activity
SLAV_RS18295	COG0738	Major facilitator superfamily
SLAV_RS18305	COG0477	Major facilitator Superfamily
SLAV_RS18320	COG0477	Major facilitator Superfamily
SLAV_RS18330	COG3835	regulator
SLAV_RS18335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SLAV_RS18340	COG2080	2 iron, 2 sulfur cluster binding
SLAV_RS18340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLAV_RS18400	COG0433	COG0433 Predicted ATPase
SLAV_RS18415	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SLAV_RS18460	COG1191	sigma factor activity
SLAV_RS18490	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLAV_RS18500	COG2205	protein histidine kinase activity
SLAV_RS18505	COG0745	RESPONSE REGULATOR receiver
SLAV_RS18565	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS18570	COG1595	DNA-templated transcription, initiation
SLAV_RS18585	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS18595	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS18625	COG2855	membrane
SLAV_RS18635	COG0583	DNA-binding transcription factor activity
SLAV_RS18640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLAV_RS18655	COG0653	protein targeting
SLAV_RS18675	COG0006	proline dipeptidase activity
SLAV_RS18705	COG2372	response to copper ion
SLAV_RS18710	COG2837	iron assimilation
SLAV_RS18720	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SLAV_RS18725	COG0561	phosphatase activity
SLAV_RS18765	COG0789	Transcriptional regulator
SLAV_RS18775	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SLAV_RS18780	COG0326	Molecular chaperone. Has ATPase activity
SLAV_RS18795	COG0561	phosphatase activity
SLAV_RS18805	COG4988	ABC transporter
SLAV_RS18810	COG1294	oxidase, subunit
SLAV_RS18815	COG1271	oxidase subunit
SLAV_RS18825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLAV_RS18830	COG1609	Transcriptional regulator
SLAV_RS18845	COG0667	Aldo Keto reductase
SLAV_RS18860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SLAV_RS18885	COG0662	Cupin 2, conserved barrel domain protein
SLAV_RS18890	COG1950	PFAM Membrane protein of
SLAV_RS18895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLAV_RS18900	COG0626	cystathionine gamma-synthase activity
SLAV_RS18930	COG0456	acetyltransferase
SLAV_RS18945	COG0305	Participates in initiation and elongation during chromosome replication
SLAV_RS18955	COG0359	binds to the 23S rRNA
SLAV_RS18960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLAV_RS18965	COG0629	single-stranded DNA binding
SLAV_RS18970	COG0360	Binds together with S18 to 16S ribosomal RNA
SLAV_RS18995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLAV_RS19015	COG0617	tRNA 3'-terminal CCA addition
SLAV_RS19030	COG2815	serine threonine protein kinase
SLAV_RS19030	COG0515	serine threonine protein kinase
SLAV_RS19035	COG1595	DNA-templated transcription, initiation
SLAV_RS19045	COG0492	ferredoxin-NADP+ reductase activity
SLAV_RS19050	COG3118	belongs to the thioredoxin family
SLAV_RS19065	COG1192	Involved in chromosome partitioning
SLAV_RS19070	COG0357	Ribosomal RNA small subunit methyltransferase G
SLAV_RS19080	COG0706	membrane insertase activity
SLAV_RS19085	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SLAV_RS19090	COG0594	ribonuclease P activity
SLAV_RS19100	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SLAV_RS19110	COG0592	DNA-directed DNA polymerase activity
SLAV_RS19115	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SLAV_RS19120	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SLAV_RS19125	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SLAV_RS19135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLAV_RS19160	COG0515	serine threonine protein kinase
SLAV_RS19185	COG1652	LysM domain
SLAV_RS19215	COG3764	Sortase (surface protein transpeptidase)
SLAV_RS19225	COG3764	Sortase (surface protein transpeptidase)
SLAV_RS19230	COG3764	Sortase (surface protein transpeptidase)
SLAV_RS19235	COG0515	serine threonine protein kinase
SLAV_RS19260	COG1716	ATPase activity
SLAV_RS19265	COG1716	ATPase activity
SLAV_RS19275	COG4585	Histidine kinase
SLAV_RS19280	COG2197	response regulator
SLAV_RS19305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLAV_RS19310	COG2151	metal-sulfur cluster biosynthetic enzyme
SLAV_RS19315	COG3396	Phenylacetate-CoA oxygenase
SLAV_RS19320	COG3460	Phenylacetate-CoA oxygenase
SLAV_RS19325	COG3396	Phenylacetate-CoA oxygenase
SLAV_RS19360	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLAV_RS19365	COG1309	transcriptional regulator
SLAV_RS19375	COG1522	sequence-specific DNA binding
SLAV_RS19395	COG3321	synthase
SLAV_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS19395	COG0604	alcohol dehydrogenase
SLAV_RS19400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SLAV_RS19410	COG0746	molybdenum cofactor guanylyltransferase activity
SLAV_RS19425	COG4591	ABC-type transport system involved in lipoprotein release permease component
SLAV_RS19425	COG1136	(ABC) transporter
SLAV_RS19445	COG0515	serine threonine protein kinase
SLAV_RS19450	COG0515	serine threonine protein kinase
SLAV_RS19470	COG0022	dehydrogenase e1 component
SLAV_RS19475	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLAV_RS19500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SLAV_RS19530	COG2271	Major facilitator Superfamily
SLAV_RS19580	COG2197	response regulator
SLAV_RS19590	COG1362	aminopeptidase activity
SLAV_RS19600	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS19650	COG0628	permease
SLAV_RS19660	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SLAV_RS19675	COG2205	protein histidine kinase activity
SLAV_RS19685	COG1289	transmembrane transporter activity
SLAV_RS19755	COG1191	sigma factor activity
SLAV_RS19775	COG0667	Aldo Keto reductase
SLAV_RS19800	COG3973	AAA domain
SLAV_RS19810	COG0596	Alpha beta hydrolase
SLAV_RS19815	COG3226	Transcriptional regulator
SLAV_RS19845	COG2192	nodulation
SLAV_RS19885	COG2226	methyltransferase
SLAV_RS19905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SLAV_RS19920	COG1132	(ABC) transporter
SLAV_RS19930	COG2197	response regulator
SLAV_RS19985	COG5492	domain, Protein
SLAV_RS19985	COG4932	domain protein
SLAV_RS20035	COG0513	Belongs to the DEAD box helicase family
SLAV_RS20040	COG1278	Cold shock
SLAV_RS20050	COG0189	ligase activity
SLAV_RS20060	COG2197	response regulator
SLAV_RS20065	COG4585	Histidine kinase
SLAV_RS20080	COG0745	RESPONSE REGULATOR receiver
SLAV_RS20100	COG0717	Belongs to the dCTP deaminase family
SLAV_RS20115	COG2181	nitrate reductase activity
SLAV_RS20115	COG0247	lactate metabolic process
SLAV_RS20120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SLAV_RS20125	COG0443	Heat shock 70 kDa protein
SLAV_RS20130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SLAV_RS20135	COG0484	heat shock protein binding
SLAV_RS20140	COG0789	Transcriptional regulator
SLAV_RS20165	COG0542	response to heat
SLAV_RS20200	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SLAV_RS20215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SLAV_RS20220	COG0191	fructose-bisphosphate aldolase activity
SLAV_RS20245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS20280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SLAV_RS20295	COG1131	(ABC) transporter
SLAV_RS20300	COG3559	Exporter of polyketide antibiotics
SLAV_RS20305	COG2124	cytochrome p450
SLAV_RS20310	COG2197	response regulator
SLAV_RS20315	COG4585	Histidine kinase
SLAV_RS20320	COG2197	response regulator
SLAV_RS20325	COG4585	Histidine kinase
SLAV_RS20365	COG0693	protein deglycase activity
SLAV_RS20370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLAV_RS20390	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SLAV_RS20395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SLAV_RS20415	COG1595	DNA-templated transcription, initiation
SLAV_RS20435	COG0402	S-adenosylhomocysteine deaminase activity
SLAV_RS20465	COG1408	metallophosphoesterase
SLAV_RS20475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLAV_RS20490	COG0003	Pfam Anion-transporting ATPase
SLAV_RS20515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLAV_RS20550	COG2267	carboxylic ester hydrolase activity
SLAV_RS20560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SLAV_RS20565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLAV_RS20570	COG0659	secondary active sulfate transmembrane transporter activity
SLAV_RS20630	COG1205	dead DEAH box helicase
SLAV_RS20630	COG1111	helicase
SLAV_RS20635	COG1366	Belongs to the anti-sigma-factor antagonist family
SLAV_RS20640	COG2172	sigma factor antagonist activity
SLAV_RS20645	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SLAV_RS20655	COG2890	protein-(glutamine-N5) methyltransferase activity
SLAV_RS20665	COG1754	DNA topoisomerase type I activity
SLAV_RS20665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SLAV_RS20670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SLAV_RS20675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SLAV_RS20765	COG1045	serine acetyltransferase
SLAV_RS20780	COG0151	Belongs to the GarS family
SLAV_RS20805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLAV_RS20805	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLAV_RS20815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLAV_RS20840	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS20845	COG2318	DinB family
SLAV_RS20850	COG0789	Transcriptional regulator
SLAV_RS20855	COG0586	Pfam SNARE associated Golgi protein
SLAV_RS20865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SLAV_RS20870	COG2027	D-alanyl-D-alanine carboxypeptidase
SLAV_RS20880	COG0037	tRNA processing
SLAV_RS20885	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SLAV_RS20895	COG0302	gtp cyclohydrolase
SLAV_RS20915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SLAV_RS20945	COG1174	glycine betaine transport
SLAV_RS20955	COG1732	Glycine betaine
SLAV_RS20975	COG0649	NAD binding
SLAV_RS21035	COG1674	ftsk spoiiie
SLAV_RS21045	COG2197	response regulator
SLAV_RS21070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLAV_RS21080	COG2843	Capsule synthesis protein
SLAV_RS21095	COG0640	Transcriptional regulator
SLAV_RS21120	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SLAV_RS21125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SLAV_RS21135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SLAV_RS21160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SLAV_RS21190	COG0739	heme binding
SLAV_RS21200	COG2205	protein histidine kinase activity
SLAV_RS21205	COG0745	RESPONSE REGULATOR receiver
SLAV_RS21215	COG1595	DNA-templated transcription, initiation
SLAV_RS21220	COG1194	a g-specific adenine glycosylase
SLAV_RS21240	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SLAV_RS21265	COG0248	Ppx GppA phosphatase
SLAV_RS21270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLAV_RS21275	COG1082	Xylose isomerase domain protein TIM barrel
SLAV_RS21285	COG0129	dihydroxy-acid dehydratase activity
SLAV_RS21295	COG4991	sh3 domain protein
SLAV_RS21310	COG0842	Transport permease protein
SLAV_RS21310	COG1129	ABC transporter
SLAV_RS21320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SLAV_RS21325	COG0180	Tryptophanyl-tRNA synthetase
SLAV_RS21350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLAV_RS21355	COG2223	nitrite transmembrane transporter activity
SLAV_RS21360	COG0123	including yeast histone deacetylase and acetoin utilization protein
SLAV_RS21415	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SLAV_RS21420	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SLAV_RS21425	COG0181	hydroxymethylbilane synthase activity
SLAV_RS21430	COG1648	precorrin-2 dehydrogenase activity
SLAV_RS21430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SLAV_RS21450	COG0113	porphobilinogen synthase activity
SLAV_RS21510	COG0018	arginyl-trna synthetase
SLAV_RS21520	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SLAV_RS21540	COG1690	Belongs to the RtcB family
SLAV_RS21560	COG1742	UPF0060 membrane protein
SLAV_RS21575	COG1733	regulation of RNA biosynthetic process
SLAV_RS21595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SLAV_RS21600	COG0406	alpha-ribazole phosphatase activity
SLAV_RS21610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLAV_RS21615	COG0785	Cytochrome C biogenesis protein
SLAV_RS21620	COG1333	cytochrome c biogenesis protein
SLAV_RS21625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SLAV_RS21650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SLAV_RS21660	COG0109	protoheme IX farnesyltransferase activity
SLAV_RS21675	COG0163	prenyltransferase activity
SLAV_RS21685	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLAV_RS21700	COG1301	dicarboxylic acid transport
SLAV_RS21740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLAV_RS21775	COG2207	Transcriptional regulator
SLAV_RS21785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLAV_RS21810	COG1686	Belongs to the peptidase S11 family
SLAV_RS21840	COG0590	tRNA wobble adenosine to inosine editing
SLAV_RS21870	COG3384	dioxygenase
SLAV_RS21885	COG0477	Major facilitator Superfamily
SLAV_RS21890	COG1349	DNA-binding transcription factor activity
SLAV_RS21950	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS21955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SLAV_RS21975	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS22050	COG1970	mechanosensitive ion channel activity
SLAV_RS22065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SLAV_RS22080	COG3263	regulation of cellular component size
SLAV_RS22090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SLAV_RS22095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLAV_RS22105	COG0315	cyclic pyranopterin monophosphate synthase activity
SLAV_RS22110	COG0315	cyclic pyranopterin monophosphate synthase activity
SLAV_RS22110	COG0521	Mo-molybdopterin cofactor biosynthetic process
SLAV_RS22115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLAV_RS22130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLAV_RS22140	COG0708	Exodeoxyribonuclease III
SLAV_RS22150	COG2072	flavoprotein involved in K transport
SLAV_RS22155	COG2267	carboxylic ester hydrolase activity
SLAV_RS22160	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS22170	COG0793	Belongs to the peptidase S41A family
SLAV_RS22170	COG4946	Tricorn protease homolog
SLAV_RS22180	COG2409	Drug exporters of the RND superfamily
SLAV_RS22190	COG0310	cobalt ion transport
SLAV_RS22200	COG1122	ATPase activity
SLAV_RS22205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLAV_RS22210	COG0768	penicillin binding
SLAV_RS22215	COG3415	Transposase
SLAV_RS22215	COG2801	Transposase and inactivated derivatives
SLAV_RS22235	COG0084	hydrolase, TatD family'
SLAV_RS22240	COG3583	domain protein
SLAV_RS22240	COG3584	3D domain protein
SLAV_RS22245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SLAV_RS22250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SLAV_RS22260	COG0488	(ABC) transporter
SLAV_RS22285	COG2197	response regulator
SLAV_RS22290	COG1846	Transcriptional regulator
SLAV_RS22295	COG4106	trans-aconitate 2-methyltransferase activity
SLAV_RS22300	COG1309	transcriptional regulator
SLAV_RS22310	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SLAV_RS22315	COG0193	aminoacyl-tRNA hydrolase activity
SLAV_RS22320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SLAV_RS22325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLAV_RS22330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SLAV_RS22340	COG4585	Histidine kinase
SLAV_RS22370	COG0596	Alpha beta hydrolase
SLAV_RS22390	COG0477	Major facilitator Superfamily
SLAV_RS22395	COG1136	(ABC) transporter
SLAV_RS22400	COG0577	efflux transmembrane transporter activity
SLAV_RS22435	COG2815	serine threonine protein kinase
SLAV_RS22435	COG0515	serine threonine protein kinase
SLAV_RS22455	COG1017	nitric oxide dioxygenase activity
SLAV_RS22455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLAV_RS22460	COG2124	cytochrome p450
SLAV_RS22475	COG0148	phosphopyruvate hydratase activity
SLAV_RS22505	COG1252	NADH dehydrogenase
SLAV_RS22510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLAV_RS22515	COG1136	(ABC) transporter
SLAV_RS22515	COG0577	efflux transmembrane transporter activity
SLAV_RS22520	COG1136	(ABC) transporter
SLAV_RS22520	COG0577	efflux transmembrane transporter activity
SLAV_RS22555	COG0183	Belongs to the thiolase family
SLAV_RS22560	COG2755	lipolytic protein G-D-S-L family
SLAV_RS22590	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SLAV_RS22595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLAV_RS22605	COG1228	amidohydrolase
SLAV_RS22630	COG3104	oligopeptide transport
SLAV_RS22635	COG0745	RESPONSE REGULATOR receiver
SLAV_RS22640	COG2205	protein histidine kinase activity
SLAV_RS22675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLAV_RS22690	COG1216	Glycosyl transferase, family 2
SLAV_RS22700	COG1316	TRANSCRIPTIONal
SLAV_RS22725	COG1316	TRANSCRIPTIONal
SLAV_RS22730	COG1316	TRANSCRIPTIONal
SLAV_RS22735	COG1316	TRANSCRIPTIONal
SLAV_RS22755	COG0778	Nitroreductase
SLAV_RS22755	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SLAV_RS22760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLAV_RS22795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLAV_RS22800	COG2835	tetraacyldisaccharide 4'-kinase activity
SLAV_RS22810	COG1482	cell wall glycoprotein biosynthetic process
SLAV_RS22820	COG0681	Belongs to the peptidase S26 family
SLAV_RS22825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SLAV_RS22825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SLAV_RS22825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLAV_RS22830	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SLAV_RS22880	COG0714	Associated with various cellular activities
SLAV_RS22900	COG0745	RESPONSE REGULATOR receiver
SLAV_RS22905	COG5002	protein histidine kinase activity
SLAV_RS22905	COG5000	phosphorelay sensor kinase activity
SLAV_RS22910	COG0823	Involved in the tonB-independent uptake of proteins
SLAV_RS22915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SLAV_RS22925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SLAV_RS22930	COG2197	response regulator
SLAV_RS22945	COG0653	protein targeting
SLAV_RS22960	COG0546	phosphoglycolate phosphatase activity
SLAV_RS22965	COG2902	Dehydrogenase
SLAV_RS22975	COG1134	teichoic acid transport
SLAV_RS22995	COG0395	ABC-type sugar transport system, permease component
SLAV_RS23000	COG1175	transmembrane transport
SLAV_RS23005	COG1653	transport
SLAV_RS23015	COG0515	serine threonine protein kinase
SLAV_RS23020	COG0515	serine threonine protein kinase
SLAV_RS23030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SLAV_RS23040	COG2884	Cell division ATP-binding protein ftsE
SLAV_RS23055	COG0793	Belongs to the peptidase S41A family
SLAV_RS23060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SLAV_RS23100	COG0583	DNA-binding transcription factor activity
SLAV_RS23115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLAV_RS23140	COG3973	AAA domain
SLAV_RS23150	COG0776	regulation of translation
SLAV_RS23155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLAV_RS23160	COG1678	Uncharacterized ACR, COG1678
SLAV_RS23170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLAV_RS23210	COG1404	Belongs to the peptidase S8 family
SLAV_RS23245	COG3654	unkown
SLAV_RS23290	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SLAV_RS23300	COG0277	FAD linked oxidase domain protein
SLAV_RS23335	COG1335	isochorismatase
SLAV_RS23345	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SLAV_RS23355	COG1113	amino acid transport
SLAV_RS23375	COG3189	MarR family transcriptional regulator
SLAV_RS23385	COG1234	tRNA 3'-trailer cleavage
SLAV_RS23390	COG1263	PTS System
SLAV_RS23395	COG1263	PTS System
SLAV_RS23400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SLAV_RS23405	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SLAV_RS23415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SLAV_RS23445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLAV_RS23460	COG4555	ABC transporter
SLAV_RS23470	COG2733	membrane
SLAV_RS23530	COG3764	Sortase (surface protein transpeptidase)
SLAV_RS23540	COG0706	membrane insertase activity
SLAV_RS23550	COG0673	inositol 2-dehydrogenase activity
SLAV_RS23555	COG1940	carbohydrate kinase activity
SLAV_RS23570	COG2188	Transcriptional regulator
SLAV_RS23575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLAV_RS23640	COG3397	chitin binding
SLAV_RS23645	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS23660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS23720	COG0406	alpha-ribazole phosphatase activity
SLAV_RS23750	COG0745	RESPONSE REGULATOR receiver
SLAV_RS23790	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SLAV_RS23795	COG4977	sequence-specific DNA binding
SLAV_RS23805	COG0589	response to stress
SLAV_RS23815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLAV_RS23855	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLAV_RS23860	COG0076	glutamate decarboxylase activity
SLAV_RS23865	COG2375	cellular response to nickel ion
SLAV_RS23875	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS23890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLAV_RS23895	COG1309	transcriptional regulator
SLAV_RS23910	COG1946	Acyl-CoA thioesterase
SLAV_RS23935	COG0028	Belongs to the TPP enzyme family
SLAV_RS23960	COG1472	Belongs to the glycosyl hydrolase 3 family
SLAV_RS23985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SLAV_RS24010	COG0673	inositol 2-dehydrogenase activity
SLAV_RS24025	COG3718	enzyme involved in inositol metabolism
SLAV_RS24030	COG3962	Belongs to the TPP enzyme family
SLAV_RS24060	COG2091	lysine biosynthetic process via aminoadipic acid
SLAV_RS24095	COG0629	single-stranded DNA binding
SLAV_RS24135	COG2346	COG2346, Truncated hemoglobins
SLAV_RS24140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLAV_RS24170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLAV_RS24185	COG1486	melibiose metabolic process
SLAV_RS24190	COG0395	ABC-type sugar transport system, permease component
SLAV_RS24195	COG1175	transmembrane transport
SLAV_RS24210	COG0668	transmembrane transport
SLAV_RS24220	COG3291	Pkd domain containing protein
SLAV_RS24220	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLAV_RS24240	COG1846	Transcriptional regulator
SLAV_RS24245	COG0697	spore germination
SLAV_RS24275	COG2234	aminopeptidase activity
SLAV_RS24290	COG2514	catechol 2,3-dioxygenase activity
SLAV_RS24310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SLAV_RS24315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SLAV_RS24320	COG1113	amino acid transport
SLAV_RS24330	COG1113	amino acid transport
SLAV_RS24340	COG1113	amino acid transport
SLAV_RS24355	COG4552	Acetyltransferase involved in intracellular survival and related
SLAV_RS24395	COG0544	peptidyl-prolyl cis-trans isomerase activity
SLAV_RS24400	COG0740	serine-type endopeptidase activity
SLAV_RS24405	COG0740	serine-type endopeptidase activity
SLAV_RS24410	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SLAV_RS24425	COG0525	valine-tRNA ligase activity
SLAV_RS24435	COG1077	Cell shape determining protein MreB Mrl
SLAV_RS24440	COG0285	dihydrofolate synthase activity
SLAV_RS24450	COG0105	UTP biosynthetic process
SLAV_RS24455	COG1077	Cell shape determining protein MreB Mrl
SLAV_RS24470	COG0768	penicillin binding
SLAV_RS24475	COG0772	Belongs to the SEDS family
SLAV_RS24500	COG1530	ribonuclease E activity
SLAV_RS24505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SLAV_RS24510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SLAV_RS24515	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SLAV_RS24520	COG1215	transferase activity, transferring glycosyl groups
SLAV_RS24530	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS24535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLAV_RS24540	COG0463	Glycosyl transferase, family 2
SLAV_RS24550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SLAV_RS24560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SLAV_RS24575	COG0501	Belongs to the peptidase M48B family
SLAV_RS24580	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SLAV_RS24590	COG0799	negative regulation of ribosome biogenesis
SLAV_RS24595	COG0588	phosphoglycerate mutase activity
SLAV_RS24615	COG0495	leucyl-tRNA aminoacylation
SLAV_RS24625	COG1307	EDD domain protein, DegV family
SLAV_RS24635	COG1596	polysaccharide export
SLAV_RS24635	COG1555	photosystem II stabilization
SLAV_RS24645	COG2353	YceI-like domain
SLAV_RS24665	COG0268	Binds directly to 16S ribosomal RNA
SLAV_RS24670	COG0481	GTPase activity
SLAV_RS24700	COG1420	regulation of RNA biosynthetic process
SLAV_RS24705	COG0484	heat shock protein binding
SLAV_RS24720	COG0537	adenosine 5'-monophosphoramidase activity
SLAV_RS24725	COG1234	tRNA 3'-trailer cleavage
SLAV_RS24740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SLAV_RS24750	COG2315	Protein conserved in bacteria
SLAV_RS24780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SLAV_RS24805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLAV_RS24810	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS24825	COG1381	Involved in DNA repair and RecF pathway recombination
SLAV_RS24830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLAV_RS24845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLAV_RS24850	COG1121	(ABC) transporter
SLAV_RS24855	COG3443	Belongs to the bacterial solute-binding protein 9 family
SLAV_RS24855	COG0803	Belongs to the bacterial solute-binding protein 9 family
SLAV_RS24860	COG0423	glycine-tRNA ligase activity
SLAV_RS24870	COG1309	transcriptional regulator
SLAV_RS24875	COG0667	Aldo Keto reductase
SLAV_RS24890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLAV_RS24890	COG0574	Belongs to the PEP-utilizing enzyme family
SLAV_RS24910	COG2146	nitrite reductase [NAD(P)H] activity
SLAV_RS24910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLAV_RS24915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLAV_RS24920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLAV_RS24920	COG1017	nitric oxide dioxygenase activity
SLAV_RS24940	COG2205	protein histidine kinase activity
SLAV_RS24955	COG0358	DNA primase activity
SLAV_RS24965	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SLAV_RS24975	COG2949	membrane
SLAV_RS24990	COG0243	molybdopterin cofactor binding
SLAV_RS25020	COG1070	Carbohydrate kinase
SLAV_RS25055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLAV_RS25075	COG0825	malonyl-CoA metabolic process
SLAV_RS25075	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SLAV_RS25085	COG1522	sequence-specific DNA binding
SLAV_RS25100	COG1077	Cell shape determining protein MreB Mrl
SLAV_RS25180	COG2130	NADP-dependent
SLAV_RS25185	COG1764	response to oxidative stress
SLAV_RS25200	COG1733	regulation of RNA biosynthetic process
SLAV_RS25215	COG1309	transcriptional regulator
SLAV_RS25235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLAV_RS25240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLAV_RS25245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLAV_RS25270	COG0789	Transcriptional regulator
SLAV_RS25275	COG0667	Aldo Keto reductase
SLAV_RS25290	COG1309	transcriptional regulator
SLAV_RS25295	COG0477	Major facilitator Superfamily
SLAV_RS25305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLAV_RS25310	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLAV_RS25360	COG1358	cellular component organization or biogenesis
SLAV_RS25510	COG2124	cytochrome p450
SLAV_RS25515	COG0183	Belongs to the thiolase family
SLAV_RS25530	COG3845	ABC transporter
SLAV_RS25570	COG1309	transcriptional regulator
SLAV_RS25575	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS25610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS25620	COG0860	N-Acetylmuramoyl-L-alanine amidase
SLAV_RS25625	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLAV_RS25630	COG3415	Transposase
SLAV_RS25630	COG2801	Transposase and inactivated derivatives
SLAV_RS25640	COG2815	serine threonine protein kinase
SLAV_RS25640	COG0515	serine threonine protein kinase
SLAV_RS25675	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS25680	COG0183	Belongs to the thiolase family
SLAV_RS25700	COG2030	dehydratase
SLAV_RS25710	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS25715	COG1011	Hydrolase
SLAV_RS25725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SLAV_RS25775	COG3022	response to hydroperoxide
SLAV_RS25790	COG1834	amidinotransferase
SLAV_RS25800	COG2814	Major facilitator Superfamily
SLAV_RS25805	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS25810	COG0463	Glycosyl transferase, family 2
SLAV_RS25820	COG0672	)-iron permease
SLAV_RS25825	COG2837	iron assimilation
SLAV_RS25835	COG1120	ATPase activity
SLAV_RS25845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SLAV_RS25895	COG0789	Transcriptional regulator
SLAV_RS25900	COG1994	Peptidase M50
SLAV_RS25920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SLAV_RS25930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLAV_RS25930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SLAV_RS25965	COG0174	glutamine synthetase
SLAV_RS25980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SLAV_RS26000	COG1228	amidohydrolase
SLAV_RS26010	COG1609	Transcriptional regulator
SLAV_RS26015	COG0366	Alpha amylase catalytic
SLAV_RS26025	COG1175	transmembrane transport
SLAV_RS26035	COG0366	Alpha amylase catalytic
SLAV_RS26095	COG2365	Tyrosine phosphatase family
SLAV_RS26115	COG0745	RESPONSE REGULATOR receiver
SLAV_RS26195	COG0321	lipoyl(octanoyl) transferase activity
SLAV_RS26200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SLAV_RS26235	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS26245	COG0515	serine threonine protein kinase
SLAV_RS26245	COG2815	serine threonine protein kinase
SLAV_RS26250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLAV_RS26260	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLAV_RS26265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SLAV_RS26270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SLAV_RS26300	COG4585	Histidine kinase
SLAV_RS26310	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SLAV_RS26310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SLAV_RS26315	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLAV_RS26330	COG2226	methyltransferase
SLAV_RS26355	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SLAV_RS26360	COG2197	response regulator
SLAV_RS26365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SLAV_RS26375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SLAV_RS26395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLAV_RS26405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SLAV_RS26410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SLAV_RS26420	COG1376	ErfK ybiS ycfS ynhG family protein
SLAV_RS26430	COG1845	cytochrome c oxidase, subunit III
SLAV_RS26435	COG2010	Cytochrome c
SLAV_RS26440	COG0723	plastoquinol--plastocyanin reductase activity
SLAV_RS26445	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLAV_RS26450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SLAV_RS26455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLAV_RS26500	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS26525	COG0003	Pfam Anion-transporting ATPase
SLAV_RS26535	COG1940	carbohydrate kinase activity
SLAV_RS26560	COG4585	Histidine kinase
SLAV_RS26565	COG2197	response regulator
SLAV_RS26570	COG0205	6-phosphofructokinase activity
SLAV_RS26575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLAV_RS26585	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SLAV_RS26595	COG2193	ferroxidase activity
SLAV_RS26600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLAV_RS26610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SLAV_RS26615	COG0515	serine threonine protein kinase
SLAV_RS26615	COG2815	serine threonine protein kinase
SLAV_RS26635	COG2022	thiamine diphosphate biosynthetic process
SLAV_RS26645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLAV_RS26645	COG2022	thiamine diphosphate biosynthetic process
SLAV_RS26660	COG0352	thiamine-phosphate diphosphorylase activity
SLAV_RS26675	COG1233	COG1233 Phytoene dehydrogenase and related
SLAV_RS26700	COG1126	abc transporter atp-binding protein
SLAV_RS26710	COG1309	transcriptional regulator
SLAV_RS26725	COG0714	Associated with various cellular activities
SLAV_RS26735	COG0275	rRNA processing
SLAV_RS26750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SLAV_RS26760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLAV_RS26765	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLAV_RS26775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SLAV_RS26780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SLAV_RS26785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SLAV_RS26800	COG1799	cell septum assembly
SLAV_RS26810	COG3599	regulation of cell shape
SLAV_RS26815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SLAV_RS26830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SLAV_RS26850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLAV_RS26855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SLAV_RS26865	COG2205	protein histidine kinase activity
SLAV_RS26905	COG0587	DNA-directed DNA polymerase activity
SLAV_RS26910	COG1432	Conserved Protein
SLAV_RS26930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SLAV_RS26945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SLAV_RS26950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLAV_RS26955	COG0131	Imidazoleglycerol-phosphate dehydratase
SLAV_RS26960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SLAV_RS26965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SLAV_RS26970	COG0251	oxidation-reduction process
SLAV_RS26975	COG0107	imidazoleglycerol-phosphate synthase activity
SLAV_RS26985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SLAV_RS27010	COG0134	indole-3-glycerol-phosphate synthase activity
SLAV_RS27020	COG0133	tryptophan synthase activity
SLAV_RS27025	COG0159	tryptophan synthase activity
SLAV_RS27035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SLAV_RS27040	COG2301	Belongs to the HpcH HpaI aldolase family
SLAV_RS27045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLAV_RS27050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLAV_RS27080	COG0070	glutamate synthase
SLAV_RS27080	COG0067	glutamate synthase
SLAV_RS27080	COG0069	glutamate synthase activity
SLAV_RS27140	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS27145	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS27150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SLAV_RS27160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS27170	COG0657	acetylesterase activity
SLAV_RS27200	COG0598	Magnesium transport protein CorA
SLAV_RS27215	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS27220	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS27225	COG1024	Enoyl-CoA hydratase
SLAV_RS27230	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS27235	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS27240	COG1309	transcriptional regulator
SLAV_RS27245	COG0183	Belongs to the thiolase family
SLAV_RS27255	COG1278	Cold shock
SLAV_RS27265	COG2365	Tyrosine phosphatase family
SLAV_RS27285	COG1024	Enoyl-CoA hydratase
SLAV_RS27295	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS27315	COG0596	Alpha beta hydrolase
SLAV_RS27320	COG0516	GMP reductase activity
SLAV_RS27320	COG0517	IMP dehydrogenase activity
SLAV_RS27345	COG0739	heme binding
SLAV_RS27350	COG0739	heme binding
SLAV_RS27355	COG3971	2-oxopent-4-enoate hydratase activity
SLAV_RS27365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLAV_RS27390	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS27395	COG2267	carboxylic ester hydrolase activity
SLAV_RS27405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SLAV_RS27410	COG1053	succinate dehydrogenase
SLAV_RS27435	COG2197	response regulator
SLAV_RS27445	COG0287	Prephenate dehydrogenase
SLAV_RS27445	COG1605	Chorismate mutase
SLAV_RS27470	COG0737	Belongs to the 5'-nucleotidase family
SLAV_RS27535	COG2050	protein possibly involved in aromatic compounds catabolism
SLAV_RS27565	COG1643	Atp-dependent helicase
SLAV_RS27570	COG2226	methyltransferase
SLAV_RS27570	COG1073	alpha beta
SLAV_RS27575	COG0539	negative regulation of cytoplasmic translation
SLAV_RS27585	COG0237	dephospho-CoA kinase activity
SLAV_RS27605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLAV_RS27630	COG1846	Transcriptional regulator
SLAV_RS27655	COG2313	pseudouridylate synthase activity
SLAV_RS27670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLAV_RS27675	COG0584	glycerophosphoryl diester phosphodiesterase
SLAV_RS27680	COG0556	nucleotide-excision repair
SLAV_RS27700	COG0477	Major facilitator Superfamily
SLAV_RS27715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLAV_RS27760	COG0322	excinuclease ABC activity
SLAV_RS27765	COG1660	Displays ATPase and GTPase activities
SLAV_RS27775	COG1481	regulation of sporulation
SLAV_RS27785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SLAV_RS27790	COG0126	phosphoglycerate kinase activity
SLAV_RS27795	COG0149	triose-phosphate isomerase activity
SLAV_RS27800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SLAV_RS27810	COG0166	Belongs to the GPI family
SLAV_RS27815	COG0363	glucosamine-6-phosphate deaminase activity
SLAV_RS27830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLAV_RS27840	COG0109	protoheme IX farnesyltransferase activity
SLAV_RS27855	COG1612	heme a metabolic process
SLAV_RS27885	COG0719	Fe-S assembly protein
SLAV_RS27895	COG0396	ATPase activity
SLAV_RS27900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLAV_RS27905	COG0822	iron-sulfur transferase activity
SLAV_RS27910	COG2151	metal-sulfur cluster biosynthetic enzyme
SLAV_RS27930	COG2076	Multidrug Resistance protein
SLAV_RS27935	COG3226	Transcriptional regulator
SLAV_RS27950	COG2171	N-acyltransferase activity
SLAV_RS28005	COG4585	Histidine kinase
SLAV_RS28010	COG2197	response regulator
SLAV_RS28030	COG0156	8-amino-7-oxononanoate synthase activity
SLAV_RS28035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SLAV_RS28060	COG1797	cobyrinic acid a,c-diamide synthase activity
SLAV_RS28075	COG1492	cobalamin metabolic process
SLAV_RS28080	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SLAV_RS28115	COG0488	(ABC) transporter
SLAV_RS28125	COG1024	Enoyl-CoA hydratase
SLAV_RS28130	COG1302	Protein conserved in bacteria
SLAV_RS28215	COG1063	alcohol dehydrogenase
SLAV_RS28230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLAV_RS28235	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SLAV_RS28255	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SLAV_RS28270	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS28275	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SLAV_RS28285	COG2186	Transcriptional regulator
SLAV_RS28305	COG3483	tryptophan 2,3-dioxygenase activity
SLAV_RS28315	COG0436	Aminotransferase
SLAV_RS28320	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS28325	COG3830	Belongs to the UPF0237 family
SLAV_RS28325	COG0560	Phosphoserine phosphatase
SLAV_RS28330	COG0842	Transport permease protein
SLAV_RS28330	COG1131	(ABC) transporter
SLAV_RS28330	COG1716	ATPase activity
SLAV_RS28345	COG2197	response regulator
SLAV_RS28360	COG1119	ATPase activity
SLAV_RS28385	COG1881	PFAM PEBP family protein
SLAV_RS28395	COG2094	Belongs to the DNA glycosylase MPG family
SLAV_RS28435	COG0647	UMP catabolic process
SLAV_RS28440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLAV_RS28445	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLAV_RS28450	COG1120	ATPase activity
SLAV_RS28470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SLAV_RS28475	COG0497	DNA recombination
SLAV_RS28480	COG0297	glycogen (starch) synthase activity
SLAV_RS28495	COG3387	PFAM Glycoside hydrolase 15-related
SLAV_RS28500	COG0504	CTP synthase activity
SLAV_RS28505	COG0494	nUDIX hydrolase
SLAV_RS28515	COG0686	Belongs to the AlaDH PNT family
SLAV_RS28530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SLAV_RS28535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SLAV_RS28540	COG1187	pseudouridine synthase activity
SLAV_RS28555	COG0494	nUDIX hydrolase
SLAV_RS28565	COG3541	Predicted nucleotidyltransferase
SLAV_RS28595	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SLAV_RS28605	COG1160	GTP binding
SLAV_RS28620	COG3583	domain protein
SLAV_RS28635	COG0671	phosphoesterase, PA-phosphatase related
SLAV_RS28645	COG0477	Major facilitator Superfamily
SLAV_RS28650	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS28655	COG1799	cell septum assembly
SLAV_RS28700	COG0641	radical SAM
SLAV_RS28735	COG0596	Alpha beta hydrolase
SLAV_RS28760	COG0587	DNA-directed DNA polymerase activity
SLAV_RS28790	COG1725	Transcriptional regulator
SLAV_RS28800	COG2755	lipolytic protein G-D-S-L family
SLAV_RS28805	COG0515	serine threonine protein kinase
SLAV_RS28815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLAV_RS28840	COG2188	Transcriptional regulator
SLAV_RS28845	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SLAV_RS28865	COG1309	transcriptional regulator
SLAV_RS28870	COG3383	formate dehydrogenase (NAD+) activity
SLAV_RS28875	COG2851	Citrate transporter
SLAV_RS28895	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS28930	COG3876	Protein conserved in bacteria
SLAV_RS28935	COG0300	oxidoreductase activity
SLAV_RS28940	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS28955	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS28980	COG2149	membrane
SLAV_RS28985	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLAV_RS29010	COG1113	amino acid transport
SLAV_RS29055	COG2175	clavaminate synthase activity
SLAV_RS29065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLAV_RS29095	COG0667	Aldo Keto reductase
SLAV_RS29100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS29110	COG0598	Magnesium transport protein CorA
SLAV_RS29130	COG0215	cysteine-tRNA ligase activity
SLAV_RS29140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SLAV_RS29145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLAV_RS29150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLAV_RS29155	COG1414	Transcriptional regulator
SLAV_RS29160	COG0646	methionine synthase
SLAV_RS29160	COG1410	methionine synthase
SLAV_RS29170	COG4166	transmembrane transport
SLAV_RS29180	COG2197	response regulator
SLAV_RS29190	COG0517	IMP dehydrogenase activity
SLAV_RS29190	COG1994	Peptidase M50
SLAV_RS29215	COG1222	aaa ATPase
SLAV_RS29220	COG4122	O-methyltransferase activity
SLAV_RS29235	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLAV_RS29240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLAV_RS29245	COG1609	Transcriptional regulator
SLAV_RS29255	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLAV_RS29290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLAV_RS29295	COG0805	protein transport
SLAV_RS29310	COG1309	transcriptional regulator
SLAV_RS29315	COG0564	pseudouridine synthase activity
SLAV_RS29330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLAV_RS29365	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SLAV_RS29370	COG1113	amino acid transport
SLAV_RS29380	COG0174	glutamine synthetase
SLAV_RS29385	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS29390	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS29425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SLAV_RS29430	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SLAV_RS29435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SLAV_RS29440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SLAV_RS29445	COG5002	protein histidine kinase activity
SLAV_RS29450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SLAV_RS29455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLAV_RS29455	COG0072	phenylalanine-tRNA ligase activity
SLAV_RS29480	COG1649	PFAM Uncharacterised BCR, COG1649
SLAV_RS29515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SLAV_RS29520	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SLAV_RS29525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SLAV_RS29530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLAV_RS29535	COG1438	arginine binding
SLAV_RS29550	COG0165	Argininosuccinate lyase
SLAV_RS29565	COG0477	Major facilitator Superfamily
SLAV_RS29575	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS29575	COG0204	Acyl-transferase
SLAV_RS29605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLAV_RS29610	COG2011	ABC-type metal ion transport system permease component
SLAV_RS29615	COG1464	Belongs to the NlpA lipoprotein family
SLAV_RS29630	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLAV_RS29635	COG1648	precorrin-2 dehydrogenase activity
SLAV_RS29635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SLAV_RS29690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SLAV_RS29700	COG0454	-acetyltransferase
SLAV_RS29700	COG0456	acetyltransferase
SLAV_RS29755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SLAV_RS29775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLAV_RS29800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SLAV_RS29805	COG1560	Kdo2-lipid A biosynthetic process
SLAV_RS29810	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS29820	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SLAV_RS29825	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SLAV_RS29830	COG0217	transcriptional regulatory protein
SLAV_RS29835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SLAV_RS29840	COG0632	four-way junction helicase activity
SLAV_RS29845	COG2255	four-way junction helicase activity
SLAV_RS29855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLAV_RS29860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLAV_RS29865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SLAV_RS29870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLAV_RS29880	COG1196	nuclear chromosome segregation
SLAV_RS29885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SLAV_RS29895	COG0124	histidyl-tRNA synthetase
SLAV_RS29905	COG1131	(ABC) transporter
SLAV_RS29930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SLAV_RS29950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SLAV_RS29955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SLAV_RS29970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SLAV_RS29980	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SLAV_RS29985	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SLAV_RS29990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SLAV_RS29995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SLAV_RS30005	COG0006	proline dipeptidase activity
SLAV_RS30010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SLAV_RS30015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SLAV_RS30025	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SLAV_RS30030	COG0540	Belongs to the ATCase OTCase family
SLAV_RS30035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLAV_RS30045	COG0505	Belongs to the CarA family
SLAV_RS30050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SLAV_RS30055	COG0167	dihydroorotate dehydrogenase activity
SLAV_RS30060	COG0284	orotidine-5'-phosphate decarboxylase activity
SLAV_RS30070	COG0194	GDP metabolic process
SLAV_RS30085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLAV_RS30100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SLAV_RS30110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS30110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS30115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SLAV_RS30120	COG2390	Transcriptional regulator
SLAV_RS30140	COG2346	COG2346, Truncated hemoglobins
SLAV_RS30155	COG0492	ferredoxin-NADP+ reductase activity
SLAV_RS30170	COG0028	Belongs to the TPP enzyme family
SLAV_RS30185	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SLAV_RS30190	COG0693	protein deglycase activity
SLAV_RS30205	COG1366	Belongs to the anti-sigma-factor antagonist family
SLAV_RS30225	COG2208	phosphoserine phosphatase activity
SLAV_RS30225	COG2770	Histidine kinase
SLAV_RS30230	COG0489	protein tyrosine kinase activity
SLAV_RS30240	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS30280	COG3548	integral membrane protein
SLAV_RS30300	COG3275	phosphorelay sensor kinase activity
SLAV_RS30305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLAV_RS30335	COG0531	amino acid
SLAV_RS30355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS30365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS30380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLAV_RS30400	COG2233	PERMEase
SLAV_RS30405	COG0738	Major facilitator superfamily
SLAV_RS30410	COG1940	carbohydrate kinase activity
SLAV_RS30410	COG1846	Transcriptional regulator
SLAV_RS30435	COG3201	nicotinamide mononucleotide transporter
SLAV_RS30440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLAV_RS30440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLAV_RS30445	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SLAV_RS30450	COG0140	phosphoribosyl-ATP diphosphatase activity
SLAV_RS30455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SLAV_RS30475	COG3415	Transposase
SLAV_RS30475	COG2801	Transposase and inactivated derivatives
SLAV_RS30515	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS30555	COG0463	Glycosyl transferase, family 2
SLAV_RS30570	COG2270	Major facilitator Superfamily
SLAV_RS30610	COG1984	allophanate hydrolase subunit 2
SLAV_RS30615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SLAV_RS30620	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SLAV_RS30650	COG0642	Histidine kinase
SLAV_RS30655	COG2018	Roadblock/LC7 domain
SLAV_RS30670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLAV_RS30685	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SLAV_RS30710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLAV_RS30720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLAV_RS30750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLAV_RS30790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SLAV_RS30800	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLAV_RS30800	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLAV_RS30830	COG1695	Transcriptional regulator
SLAV_RS30845	COG0697	spore germination
SLAV_RS30860	COG0697	spore germination
SLAV_RS30875	COG1335	isochorismatase
SLAV_RS30900	COG0747	negative chemotaxis
SLAV_RS30905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLAV_RS30920	COG2318	DinB family
SLAV_RS30930	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SLAV_RS30940	COG1968	undecaprenyl-diphosphatase activity
SLAV_RS30955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLAV_RS30995	COG0110	maltose O-acetyltransferase activity
SLAV_RS31010	COG1832	CoA-binding protein
SLAV_RS31015	COG1739	Uncharacterized protein family UPF0029
SLAV_RS31025	COG0420	3'-5' exonuclease activity
SLAV_RS31030	COG0419	ATPase involved in DNA repair
SLAV_RS31035	COG1522	sequence-specific DNA binding
SLAV_RS31065	COG2188	Transcriptional regulator
SLAV_RS31075	COG1940	carbohydrate kinase activity
SLAV_RS31080	COG2197	response regulator
SLAV_RS31085	COG4585	Histidine kinase
SLAV_RS31110	COG3896	Chloramphenicol phosphotransferase-like protein
SLAV_RS31120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLAV_RS31155	COG2226	methyltransferase
SLAV_RS31160	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SLAV_RS31165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLAV_RS31170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SLAV_RS31175	COG0156	8-amino-7-oxononanoate synthase activity
SLAV_RS31195	COG0831	urea catabolic process
SLAV_RS31200	COG0832	Belongs to the urease beta subunit family
SLAV_RS31205	COG0804	urea catabolic process
SLAV_RS31210	COG0830	nickel cation binding
SLAV_RS31215	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SLAV_RS31220	COG0829	nickel cation binding
SLAV_RS31230	COG0204	Acyl-transferase
SLAV_RS31240	COG0205	6-phosphofructokinase activity
SLAV_RS31245	COG3442	glutamine amidotransferase
SLAV_RS31255	COG0242	peptide deformylase activity
SLAV_RS31265	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS31295	COG0601	transmembrane transport
SLAV_RS31300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLAV_RS31305	COG0444	Belongs to the ABC transporter superfamily
SLAV_RS31310	COG4608	Belongs to the ABC transporter superfamily
SLAV_RS31325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLAV_RS31335	COG4585	Histidine kinase
SLAV_RS31340	COG2197	response regulator
SLAV_RS31345	COG2318	DinB family
SLAV_RS31365	COG4166	transmembrane transport
SLAV_RS31370	COG0601	transmembrane transport
SLAV_RS31385	COG0586	Pfam SNARE associated Golgi protein
SLAV_RS31425	COG0298	carbon dioxide binding
SLAV_RS31435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SLAV_RS31440	COG0375	protein maturation
SLAV_RS31480	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SLAV_RS31480	COG1024	Enoyl-CoA hydratase
SLAV_RS31540	COG3290	protein histidine kinase activity
SLAV_RS31550	COG0514	ATP-dependent DNA helicase (RecQ)
SLAV_RS31555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS31560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLAV_RS31565	COG1126	abc transporter atp-binding protein
SLAV_RS31570	COG0765	amino acid transport
SLAV_RS31575	COG0765	amino acid transport
SLAV_RS31585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLAV_RS31590	COG1126	abc transporter atp-binding protein
SLAV_RS31615	COG2326	polyphosphate kinase activity
SLAV_RS31625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SLAV_RS31660	COG2957	Belongs to the agmatine deiminase family
SLAV_RS31665	COG0747	negative chemotaxis
SLAV_RS31675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLAV_RS31685	COG4608	Belongs to the ABC transporter superfamily
SLAV_RS31695	COG2957	Belongs to the agmatine deiminase family
SLAV_RS31760	COG2890	protein-(glutamine-N5) methyltransferase activity
SLAV_RS31795	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SLAV_RS31800	COG0483	inositol monophosphate 1-phosphatase activity
SLAV_RS31815	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS31840	COG1012	belongs to the aldehyde dehydrogenase family
SLAV_RS31855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLAV_RS31915	COG2018	Roadblock/LC7 domain
SLAV_RS31925	COG3012	SEC-C Motif Domain Protein
SLAV_RS31930	COG1946	Acyl-CoA thioesterase
SLAV_RS31945	COG1132	(ABC) transporter
SLAV_RS31950	COG1132	(ABC) transporter
SLAV_RS31955	COG0277	FAD linked oxidase domain protein
SLAV_RS31975	COG2072	flavoprotein involved in K transport
SLAV_RS31990	COG1116	anion transmembrane transporter activity
SLAV_RS31995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLAV_RS32010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLAV_RS32025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLAV_RS32035	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLAV_RS32040	COG0702	epimerase
SLAV_RS32055	COG1595	DNA-templated transcription, initiation
SLAV_RS32065	COG0406	alpha-ribazole phosphatase activity
SLAV_RS32120	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
SLAV_RS32125	COG2706	6-phosphogluconolactonase activity
SLAV_RS32135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLAV_RS32145	COG1902	pentaerythritol trinitrate reductase activity
SLAV_RS32150	COG0640	Transcriptional regulator
SLAV_RS32155	COG0493	'glutamate synthase
SLAV_RS32170	COG1309	transcriptional regulator
SLAV_RS32175	COG4221	oxidoreductase activity
SLAV_RS32195	COG0584	glycerophosphoryl diester phosphodiesterase
SLAV_RS32205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS32255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SLAV_RS32270	COG0494	nUDIX hydrolase
SLAV_RS32275	COG0477	Major facilitator Superfamily
SLAV_RS32280	COG4106	trans-aconitate 2-methyltransferase activity
SLAV_RS32290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLAV_RS32325	COG0583	DNA-binding transcription factor activity
SLAV_RS32355	COG1940	carbohydrate kinase activity
SLAV_RS32380	COG0464	growth
SLAV_RS32405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SLAV_RS32440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLAV_RS32470	COG0842	Transport permease protein
SLAV_RS32470	COG1131	(ABC) transporter
SLAV_RS32470	COG1716	ATPase activity
SLAV_RS32510	COG0725	ABC transporter, periplasmic molybdate-binding protein
SLAV_RS32515	COG3585	molybdate ion transport
SLAV_RS32530	COG1461	Dihydroxyacetone kinase
SLAV_RS32535	COG2376	Dihydroxyacetone kinase
SLAV_RS32550	COG2124	cytochrome p450
SLAV_RS32585	COG2259	Doxx family
SLAV_RS32590	COG3387	PFAM Glycoside hydrolase 15-related
SLAV_RS32615	COG1063	alcohol dehydrogenase
SLAV_RS32620	COG0156	8-amino-7-oxononanoate synthase activity
SLAV_RS32630	COG1349	DNA-binding transcription factor activity
SLAV_RS32670	COG0515	serine threonine protein kinase
SLAV_RS32675	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS32750	COG2304	oxidoreductase activity
SLAV_RS32760	COG1113	amino acid transport
SLAV_RS32780	COG0515	serine threonine protein kinase
SLAV_RS32780	COG2815	serine threonine protein kinase
SLAV_RS32815	COG2070	2-Nitropropane dioxygenase
SLAV_RS32825	COG0387	Pfam Sodium calcium exchanger
SLAV_RS32855	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS32885	COG0596	Alpha beta hydrolase
SLAV_RS32965	COG1053	succinate dehydrogenase
SLAV_RS32990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLAV_RS32990	COG2010	Cytochrome c
SLAV_RS32995	COG2080	2 iron, 2 sulfur cluster binding
SLAV_RS33005	COG0531	amino acid
SLAV_RS33015	COG0501	Belongs to the peptidase M48B family
SLAV_RS33040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLAV_RS33050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SLAV_RS33085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLAV_RS33115	COG0789	Transcriptional regulator
SLAV_RS33150	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS33210	COG0513	Belongs to the DEAD box helicase family
SLAV_RS33215	COG1846	Transcriptional regulator
SLAV_RS33225	COG1278	Cold shock
SLAV_RS33235	COG2124	cytochrome p450
SLAV_RS33270	COG4941	Belongs to the sigma-70 factor family
SLAV_RS33280	COG1136	(ABC) transporter
SLAV_RS33295	COG4591	ABC-type transport system involved in lipoprotein release permease component
SLAV_RS33295	COG1136	(ABC) transporter
SLAV_RS33305	COG2319	Wd-40 repeat
SLAV_RS33305	COG4249	Peptidase C14 caspase catalytic subunit p20
SLAV_RS33315	COG0583	DNA-binding transcription factor activity
SLAV_RS33325	COG2188	Transcriptional regulator
SLAV_RS33345	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SLAV_RS33350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLAV_RS33360	COG2188	Transcriptional regulator
SLAV_RS33370	COG2175	clavaminate synthase activity
SLAV_RS33385	COG1063	alcohol dehydrogenase
SLAV_RS33460	COG1404	Belongs to the peptidase S8 family
SLAV_RS33510	COG0714	Associated with various cellular activities
SLAV_RS33530	COG1846	Transcriptional regulator
SLAV_RS33535	COG1846	Transcriptional regulator
SLAV_RS33540	COG1764	response to oxidative stress
SLAV_RS33555	COG2197	response regulator
SLAV_RS33595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLAV_RS33630	COG0697	spore germination
SLAV_RS33715	COG1686	Belongs to the peptidase S11 family
SLAV_RS33720	COG1725	Transcriptional regulator
SLAV_RS33725	COG1131	(ABC) transporter
SLAV_RS33745	COG0477	Major facilitator Superfamily
SLAV_RS33765	COG0667	Aldo Keto reductase
SLAV_RS33770	COG1505	serine-type exopeptidase activity
SLAV_RS33795	COG0583	DNA-binding transcription factor activity
SLAV_RS33800	COG3511	phospholipase C
SLAV_RS33815	COG4585	Histidine kinase
SLAV_RS33820	COG2197	response regulator
SLAV_RS33830	COG2135	peptidase activity
SLAV_RS33845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLAV_RS33855	COG2264	protein methyltransferase activity
SLAV_RS33865	COG2011	ABC-type metal ion transport system permease component
SLAV_RS33870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLAV_RS33875	COG1464	Belongs to the NlpA lipoprotein family
SLAV_RS33890	COG1131	(ABC) transporter
SLAV_RS33930	COG0583	DNA-binding transcription factor activity
SLAV_RS33935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SLAV_RS33945	COG1113	amino acid transport
SLAV_RS33980	COG2890	protein-(glutamine-N5) methyltransferase activity
SLAV_RS34035	COG1252	NADH dehydrogenase
SLAV_RS34055	COG0009	L-threonylcarbamoyladenylate synthase
SLAV_RS34085	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SLAV_RS34110	COG2070	2-Nitropropane dioxygenase
SLAV_RS34130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLAV_RS34145	COG1940	carbohydrate kinase activity
SLAV_RS34150	COG1063	alcohol dehydrogenase
SLAV_RS34165	COG0501	Belongs to the peptidase M48B family
SLAV_RS34170	COG1796	DNA polymerase
SLAV_RS34170	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SLAV_RS34220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SLAV_RS34225	COG1509	lysine 2,3-aminomutase activity
SLAV_RS34235	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SLAV_RS34245	COG0488	(ABC) transporter
SLAV_RS34250	COG3387	PFAM Glycoside hydrolase 15-related
SLAV_RS34270	COG2239	Acts as a magnesium transporter
SLAV_RS34275	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
SLAV_RS34280	COG2205	protein histidine kinase activity
SLAV_RS34285	COG0745	RESPONSE REGULATOR receiver
SLAV_RS34290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLAV_RS34305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLAV_RS34305	COG0574	Belongs to the PEP-utilizing enzyme family
SLAV_RS34330	COG1024	Enoyl-CoA hydratase
SLAV_RS34355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SLAV_RS34395	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS34410	COG1136	(ABC) transporter
SLAV_RS34410	COG0577	efflux transmembrane transporter activity
SLAV_RS34430	COG2957	Belongs to the agmatine deiminase family
SLAV_RS34455	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SLAV_RS34475	COG2017	converts alpha-aldose to the beta-anomer
SLAV_RS34490	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS34495	COG1271	oxidase subunit
SLAV_RS34515	COG3387	PFAM Glycoside hydrolase 15-related
SLAV_RS34545	COG0501	Belongs to the peptidase M48B family
SLAV_RS34550	COG1968	undecaprenyl-diphosphatase activity
SLAV_RS34580	COG0516	GMP reductase activity
SLAV_RS34580	COG0517	IMP dehydrogenase activity
SLAV_RS34585	COG1902	pentaerythritol trinitrate reductase activity
SLAV_RS34600	COG1024	Enoyl-CoA hydratase
SLAV_RS34615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLAV_RS34625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SLAV_RS34655	COG2409	Drug exporters of the RND superfamily
SLAV_RS34660	COG5002	protein histidine kinase activity
SLAV_RS34665	COG0745	RESPONSE REGULATOR receiver
SLAV_RS34675	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLAV_RS34680	COG1129	ABC transporter
SLAV_RS34685	COG3284	Transcriptional regulator
SLAV_RS34705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLAV_RS34715	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS34745	COG2345	Transcriptional regulator
SLAV_RS34750	COG0110	maltose O-acetyltransferase activity
SLAV_RS34755	COG0366	Alpha amylase catalytic
SLAV_RS34835	COG0464	growth
SLAV_RS34880	COG3386	PFAM SMP-30 Gluconolaconase
SLAV_RS34890	COG0546	phosphoglycolate phosphatase activity
SLAV_RS34895	COG2824	Alkylphosphonate utilization operon protein PhnA
SLAV_RS34950	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS34960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SLAV_RS35000	COG4989	oxidoreductase activity
SLAV_RS35025	COG2353	YceI-like domain
SLAV_RS35030	COG0656	L-ascorbic acid biosynthetic process
SLAV_RS35085	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS35090	COG1957	nucleoside hydrolase
SLAV_RS35110	COG4221	oxidoreductase activity
SLAV_RS35155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLAV_RS35160	COG0765	amino acid transport
SLAV_RS35165	COG1126	abc transporter atp-binding protein
SLAV_RS35185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLAV_RS35190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLAV_RS35245	COG0154	amidase activity
SLAV_RS35295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLAV_RS35305	COG0154	amidase activity
SLAV_RS35320	COG1278	Cold shock
SLAV_RS35340	COG2205	protein histidine kinase activity
SLAV_RS35345	COG0745	RESPONSE REGULATOR receiver
SLAV_RS35430	COG0577	efflux transmembrane transporter activity
SLAV_RS35430	COG1136	(ABC) transporter
SLAV_RS35435	COG2205	protein histidine kinase activity
SLAV_RS35440	COG0745	RESPONSE REGULATOR receiver
SLAV_RS35460	COG4977	sequence-specific DNA binding
SLAV_RS35490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLAV_RS35530	COG0477	Major facilitator Superfamily
SLAV_RS35560	COG2226	methyltransferase
SLAV_RS35570	COG2318	DinB family
SLAV_RS35600	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS35610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLAV_RS35615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLAV_RS35635	COG1309	transcriptional regulator
SLAV_RS35640	COG0488	(ABC) transporter
SLAV_RS35655	COG0402	S-adenosylhomocysteine deaminase activity
SLAV_RS35670	COG0492	ferredoxin-NADP+ reductase activity
SLAV_RS35745	COG1595	DNA-templated transcription, initiation
SLAV_RS35785	COG2130	NADP-dependent
SLAV_RS35825	COG1819	glycosyl
SLAV_RS35895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SLAV_RS35905	COG2197	response regulator
SLAV_RS35905	COG3903	Transcriptional regulator
SLAV_RS35920	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SLAV_RS35935	COG2409	Drug exporters of the RND superfamily
SLAV_RS35950	COG0038	chloride channel
SLAV_RS35960	COG0431	NADPH-dependent FMN reductase
SLAV_RS35970	COG3118	belongs to the thioredoxin family
SLAV_RS35970	COG0492	ferredoxin-NADP+ reductase activity
SLAV_RS36005	COG2124	cytochrome p450
SLAV_RS36060	COG0596	Alpha beta hydrolase
SLAV_RS36060	COG2945	thiolester hydrolase activity
SLAV_RS36085	COG3291	Pkd domain containing protein
SLAV_RS36145	COG4221	oxidoreductase activity
SLAV_RS36185	COG2197	response regulator
SLAV_RS36205	COG2378	regulation of single-species biofilm formation
SLAV_RS36225	COG0789	Transcriptional regulator
SLAV_RS36230	COG1819	glycosyl
SLAV_RS36240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLAV_RS36270	COG0640	Transcriptional regulator
SLAV_RS36325	COG0583	DNA-binding transcription factor activity
SLAV_RS36390	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS36420	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLAV_RS36445	COG1309	transcriptional regulator
SLAV_RS36450	COG0604	alcohol dehydrogenase
SLAV_RS36500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLAV_RS36510	COG0254	rRNA binding
SLAV_RS36515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLAV_RS36520	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLAV_RS36540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SLAV_RS36555	COG3655	Transcriptional regulator
SLAV_RS36570	COG2267	carboxylic ester hydrolase activity
SLAV_RS36650	COG1428	Deoxynucleoside kinase
SLAV_RS36740	COG1619	proteins homologs of microcin C7 resistance protein MccF
SLAV_RS36765	COG0671	phosphoesterase, PA-phosphatase related
SLAV_RS36805	COG2814	Major facilitator Superfamily
SLAV_RS36845	COG2267	carboxylic ester hydrolase activity
SLAV_RS36890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLAV_RS37100	COG1309	transcriptional regulator
SLAV_RS37155	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS37180	COG0681	Belongs to the peptidase S26 family
SLAV_RS37205	COG2188	Transcriptional regulator
SLAV_RS37230	COG0662	Cupin 2, conserved barrel domain protein
SLAV_RS37270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLAV_RS37280	COG1132	(ABC) transporter
SLAV_RS37285	COG1132	(ABC) transporter
SLAV_RS37305	COG1509	lysine 2,3-aminomutase activity
SLAV_RS37330	COG0673	inositol 2-dehydrogenase activity
SLAV_RS37335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLAV_RS37340	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLAV_RS37360	COG3173	Aminoglycoside phosphotransferase
SLAV_RS37405	COG0531	amino acid
SLAV_RS37445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLAV_RS37580	COG0702	epimerase
SLAV_RS37590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SLAV_RS37605	COG0784	Response regulator, receiver
SLAV_RS37610	COG4251	negative regulation of phosphorylation
SLAV_RS37630	COG1846	Transcriptional regulator
SLAV_RS37635	COG0671	phosphoesterase, PA-phosphatase related
SLAV_RS37785	COG0667	Aldo Keto reductase
SLAV_RS37825	COG2249	NAD(P)H dehydrogenase (quinone) activity
SLAV_RS37830	COG1132	(ABC) transporter
SLAV_RS37835	COG3629	intracellular signal transduction
SLAV_RS37910	COG2233	PERMEase
SLAV_RS37945	COG0326	Molecular chaperone. Has ATPase activity
SLAV_RS37960	COG3751	2OG-Fe(II) oxygenase superfamily
SLAV_RS38015	COG3903	Transcriptional regulator
SLAV_RS38015	COG3629	intracellular signal transduction
SLAV_RS38090	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SLAV_RS38095	COG0587	DNA-directed DNA polymerase activity
SLAV_RS38100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SLAV_RS38160	COG3237	CsbD-like
SLAV_RS38235	COG0071	Belongs to the small heat shock protein (HSP20) family
SLAV_RS38255	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS38270	COG1335	isochorismatase
SLAV_RS38280	COG2124	cytochrome p450
SLAV_RS38290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLAV_RS38315	COG3293	Transposase
SLAV_RS38330	COG1278	Cold shock
SLAV_RS38445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLAV_RS38445	COG0515	serine threonine protein kinase
SLAV_RS38455	COG0515	serine threonine protein kinase
SLAV_RS38455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLAV_RS38505	COG1105	Belongs to the carbohydrate kinase PfkB family
SLAV_RS38510	COG1940	carbohydrate kinase activity
SLAV_RS38515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLAV_RS38525	COG0395	ABC-type sugar transport system, permease component
SLAV_RS38540	COG1609	Transcriptional regulator
SLAV_RS38565	COG3293	Transposase
SLAV_RS38650	COG4585	Histidine kinase
SLAV_RS38655	COG2197	response regulator
SLAV_RS38760	COG2197	response regulator
SLAV_RS38765	COG4585	Histidine kinase
SLAV_RS38810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS38835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS38845	COG0017	Asparaginyl-tRNA synthetase
SLAV_RS38865	COG1028	Short-chain dehydrogenase reductase Sdr
SLAV_RS38910	COG1404	Belongs to the peptidase S8 family
SLAV_RS39085	COG0181	hydroxymethylbilane synthase activity
SLAV_RS39090	COG1660	Displays ATPase and GTPase activities
SLAV_RS39120	COG3547	Transposase (IS116 IS110 IS902 family)
SLAV_RS39160	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLAV_RS39180	COG2188	Transcriptional regulator
SLAV_RS39270	COG0741	lytic transglycosylase activity
SLAV_RS39270	COG0791	NLP P60 protein
SLAV_RS39355	COG1215	transferase activity, transferring glycosyl groups
SLAV_RS39370	COG0438	transferase activity, transferring glycosyl groups
SLAV_RS39450	COG2226	methyltransferase
SLAV_RS39535	COG2197	response regulator
SLAV_RS39570	COG3293	Transposase
SLAV_RS39610	COG0640	Transcriptional regulator
SLAV_RS39720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SLAV_RS39725	COG1309	transcriptional regulator
SLAV_RS39730	COG0596	Alpha beta hydrolase
SLAV_RS39740	COG1013	pyruvate-flavodoxin oxidoreductase activity
SLAV_RS39745	COG0674	pyruvate-flavodoxin oxidoreductase activity
SLAV_RS39745	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SLAV_RS39765	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS39790	COG3903	Transcriptional regulator
SLAV_RS39790	COG3629	intracellular signal transduction
SLAV_RS39800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLAV_RS39805	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SLAV_RS39825	COG0529	Catalyzes the synthesis of activated sulfate
SLAV_RS39830	COG0175	sulfate reduction
SLAV_RS39845	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLAV_RS39855	COG5504	Zn-dependent protease
SLAV_RS39860	COG0076	glutamate decarboxylase activity
SLAV_RS39950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SLAV_RS39975	COG1022	Amp-dependent synthetase and ligase
SLAV_RS39980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLAV_RS39980	COG2226	methyltransferase
SLAV_RS39980	COG3433	isochorismatase activity
SLAV_RS39985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLAV_RS40035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLAV_RS40060	COG0697	spore germination
SLAV_RS40065	COG0596	Alpha beta hydrolase
SLAV_RS40080	COG1595	DNA-templated transcription, initiation
SLAV_RS40090	COG0318	PFAM AMP-dependent synthetase and ligase
SLAV_RS40095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SLAV_RS40120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SLAV_RS40125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SLAV_RS40130	COG1960	acyl-CoA dehydrogenase activity
SLAV_RS40145	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLAV_RS40150	COG3629	intracellular signal transduction
SLAV_RS40160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLAV_RS40165	COG1902	pentaerythritol trinitrate reductase activity
SLAV_RS40170	COG2313	pseudouridylate synthase activity
SLAV_RS40175	COG1942	4-Oxalocrotonate Tautomerase
SLAV_RS40180	COG0697	spore germination
SLAV_RS40190	COG0135	phosphoribosylanthranilate isomerase activity
SLAV_RS40235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLAV_RS40240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SLAV_RS40280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLAV_RS40310	COG0745	RESPONSE REGULATOR receiver
SLAV_RS40315	COG1309	transcriptional regulator
SLAV_RS40345	COG0702	epimerase
SLAV_RS40355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLAV_RS40375	COG0596	Alpha beta hydrolase
SLAV_RS40375	COG2945	thiolester hydrolase activity
SLAV_RS40390	COG2318	DinB family
SLAV_RS40395	COG0596	Alpha beta hydrolase
SLAV_RS40420	COG0475	glutathione-regulated potassium exporter activity
SLAV_RS40440	COG1192	Involved in chromosome partitioning
SLAV_RS40445	COG1475	DNA binding
SLAV_RS40470	COG1063	alcohol dehydrogenase
SLAV_RS40475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SLAV_RS40480	COG0477	Major facilitator Superfamily
SLAV_RS40495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLAV_RS40500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLAV_RS40505	COG1410	methionine synthase
SLAV_RS40505	COG0646	methionine synthase
SLAV_RS40525	COG2132	Multicopper oxidase
SLAV_RS40535	COG4221	oxidoreductase activity
SLAV_RS40550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLAV_RS40555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLAV_RS40560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family