locus-tag	class	description
Srufu_RS00020	COG3415	Transposase
Srufu_RS00020	COG2801	Transposase and inactivated derivatives
Srufu_RS00065	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS00075	COG0494	nUDIX hydrolase
Srufu_RS00145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Srufu_RS00155	COG1231	oxidoreductase activity
Srufu_RS00175	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Srufu_RS00195	COG1902	pentaerythritol trinitrate reductase activity
Srufu_RS00200	COG0789	Transcriptional regulator
Srufu_RS00225	COG1802	Transcriptional regulator
Srufu_RS00230	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS00235	COG3938	Belongs to the proline racemase family
Srufu_RS00255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Srufu_RS00270	COG3979	chitinase
Srufu_RS00305	COG4585	Histidine kinase
Srufu_RS00335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Srufu_RS00335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Srufu_RS00340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Srufu_RS00370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Srufu_RS00375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Srufu_RS00420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Srufu_RS00525	COG1191	sigma factor activity
Srufu_RS00530	COG4257	antibiotic catabolic process
Srufu_RS00535	COG2770	Histidine kinase
Srufu_RS00535	COG2208	phosphoserine phosphatase activity
Srufu_RS00570	COG0583	DNA-binding transcription factor activity
Srufu_RS00575	COG0531	amino acid
Srufu_RS00580	COG0583	DNA-binding transcription factor activity
Srufu_RS00605	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Srufu_RS00625	COG0537	adenosine 5'-monophosphoramidase activity
Srufu_RS00640	COG0596	Alpha beta hydrolase
Srufu_RS00655	COG1959	2 iron, 2 sulfur cluster binding
Srufu_RS00660	COG1017	nitric oxide dioxygenase activity
Srufu_RS00660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Srufu_RS00680	COG2252	PERMEase
Srufu_RS00710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Srufu_RS00710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Srufu_RS00715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Srufu_RS00715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Srufu_RS00755	COG0431	NADPH-dependent FMN reductase
Srufu_RS00760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Srufu_RS00765	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Srufu_RS00770	COG2080	2 iron, 2 sulfur cluster binding
Srufu_RS00810	COG1595	DNA-templated transcription, initiation
Srufu_RS00825	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Srufu_RS00845	COG0142	geranyltranstransferase activity
Srufu_RS00850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS00855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS00860	COG0477	Major facilitator Superfamily
Srufu_RS00890	COG4585	Histidine kinase
Srufu_RS00895	COG2197	response regulator
Srufu_RS00935	COG0328	RNA-DNA hybrid ribonuclease activity
Srufu_RS00960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Srufu_RS00975	COG2409	Drug exporters of the RND superfamily
Srufu_RS01035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Srufu_RS01040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Srufu_RS01045	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Srufu_RS01050	COG0110	maltose O-acetyltransferase activity
Srufu_RS01060	COG0297	glycogen (starch) synthase activity
Srufu_RS01100	COG2301	Belongs to the HpcH HpaI aldolase family
Srufu_RS01265	COG1652	LysM domain
Srufu_RS01285	COG0583	DNA-binding transcription factor activity
Srufu_RS01300	COG1846	Transcriptional regulator
Srufu_RS01380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Srufu_RS01390	COG1349	DNA-binding transcription factor activity
Srufu_RS01400	COG3290	protein histidine kinase activity
Srufu_RS01420	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS01435	COG1793	dna ligase
Srufu_RS01450	COG0531	amino acid
Srufu_RS01460	COG2837	iron assimilation
Srufu_RS01470	COG0409	Hydrogenase expression formation protein
Srufu_RS01475	COG0298	carbon dioxide binding
Srufu_RS01480	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Srufu_RS01485	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Srufu_RS01490	COG0375	protein maturation
Srufu_RS01535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Srufu_RS01540	COG2186	Transcriptional regulator
Srufu_RS01555	COG0477	Major facilitator Superfamily
Srufu_RS01570	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS01580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Srufu_RS01605	COG3960	tartronate-semialdehyde synthase activity
Srufu_RS01615	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS01625	COG0242	peptide deformylase activity
Srufu_RS01635	COG3442	glutamine amidotransferase
Srufu_RS01640	COG0205	6-phosphofructokinase activity
Srufu_RS01665	COG0693	protein deglycase activity
Srufu_RS01710	COG0829	nickel cation binding
Srufu_RS01715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Srufu_RS01720	COG0830	nickel cation binding
Srufu_RS01725	COG0804	urea catabolic process
Srufu_RS01730	COG0832	Belongs to the urease beta subunit family
Srufu_RS01735	COG0831	urea catabolic process
Srufu_RS01870	COG4948	Mandelate Racemase Muconate Lactonizing
Srufu_RS01925	COG0305	Participates in initiation and elongation during chromosome replication
Srufu_RS01935	COG2826	transposase and inactivated derivatives, IS30 family
Srufu_RS02020	COG0076	glutamate decarboxylase activity
Srufu_RS02055	COG0740	serine-type endopeptidase activity
Srufu_RS02075	COG1280	lysine exporter protein (LysE YggA)
Srufu_RS02080	COG0583	DNA-binding transcription factor activity
Srufu_RS02100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Srufu_RS02105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Srufu_RS02110	COG2226	methyltransferase
Srufu_RS02145	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS02195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Srufu_RS02225	COG1940	carbohydrate kinase activity
Srufu_RS02230	COG2188	Transcriptional regulator
Srufu_RS02240	COG1595	DNA-templated transcription, initiation
Srufu_RS02265	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS02270	COG1522	sequence-specific DNA binding
Srufu_RS02280	COG0420	3'-5' exonuclease activity
Srufu_RS02295	COG0577	efflux transmembrane transporter activity
Srufu_RS02295	COG1136	(ABC) transporter
Srufu_RS02300	COG1136	(ABC) transporter
Srufu_RS02300	COG0577	efflux transmembrane transporter activity
Srufu_RS02305	COG1739	Uncharacterized protein family UPF0029
Srufu_RS02315	COG1832	CoA-binding protein
Srufu_RS02335	COG0110	maltose O-acetyltransferase activity
Srufu_RS02425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Srufu_RS02440	COG1968	undecaprenyl-diphosphatase activity
Srufu_RS02485	COG2770	Histidine kinase
Srufu_RS02485	COG2208	phosphoserine phosphatase activity
Srufu_RS02505	COG1940	carbohydrate kinase activity
Srufu_RS02515	COG1175	transmembrane transport
Srufu_RS02520	COG0395	ABC-type sugar transport system, permease component
Srufu_RS02525	COG2723	6-phospho-beta-galactosidase activity
Srufu_RS02530	COG1764	response to oxidative stress
Srufu_RS02535	COG1846	Transcriptional regulator
Srufu_RS02545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS02585	COG0739	heme binding
Srufu_RS02590	COG0702	epimerase
Srufu_RS02615	COG1278	Cold shock
Srufu_RS02620	COG1686	Belongs to the peptidase S11 family
Srufu_RS02625	COG2356	endonuclease I
Srufu_RS02645	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Srufu_RS02655	COG3012	SEC-C Motif Domain Protein
Srufu_RS02670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Srufu_RS02685	COG2270	Major facilitator Superfamily
Srufu_RS02700	COG1216	Glycosyl transferase, family 2
Srufu_RS02710	COG1228	amidohydrolase
Srufu_RS02735	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS02750	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS02795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Srufu_RS02810	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Srufu_RS02840	COG0531	amino acid
Srufu_RS02895	COG1309	transcriptional regulator
Srufu_RS02975	COG1231	oxidoreductase activity
Srufu_RS02980	COG3961	Belongs to the TPP enzyme family
Srufu_RS03000	COG2205	protein histidine kinase activity
Srufu_RS03010	COG4166	transmembrane transport
Srufu_RS03075	COG1609	Transcriptional regulator
Srufu_RS03080	COG1957	nucleoside hydrolase
Srufu_RS03085	COG0477	Major facilitator Superfamily
Srufu_RS03105	COG1335	isochorismatase
Srufu_RS03115	COG1252	NADH dehydrogenase
Srufu_RS03135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Srufu_RS03150	COG1113	amino acid transport
Srufu_RS03170	COG0326	Molecular chaperone. Has ATPase activity
Srufu_RS03185	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS03225	COG1902	pentaerythritol trinitrate reductase activity
Srufu_RS03235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Srufu_RS03260	COG2706	6-phosphogluconolactonase activity
Srufu_RS03275	COG4213	ABC transporter substrate-binding protein
Srufu_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS03305	COG1304	FMN binding
Srufu_RS03310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Srufu_RS03315	COG2271	Major facilitator Superfamily
Srufu_RS03325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Srufu_RS03350	COG1254	Belongs to the acylphosphatase family
Srufu_RS03365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Srufu_RS03370	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Srufu_RS03375	COG2080	2 iron, 2 sulfur cluster binding
Srufu_RS03405	COG1846	Transcriptional regulator
Srufu_RS03430	COG2018	Roadblock/LC7 domain
Srufu_RS03450	COG0583	DNA-binding transcription factor activity
Srufu_RS03465	COG1473	amidohydrolase
Srufu_RS03480	COG2814	Major facilitator Superfamily
Srufu_RS03550	COG1720	tRNA m6t6A37 methyltransferase activity
Srufu_RS03615	COG2084	Dehydrogenase
Srufu_RS03620	COG3622	Belongs to the hyi family
Srufu_RS03630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Srufu_RS03655	COG1396	sequence-specific DNA binding
Srufu_RS03695	COG2801	Transposase and inactivated derivatives
Srufu_RS03695	COG3415	Transposase
Srufu_RS03770	COG1191	sigma factor activity
Srufu_RS03775	COG3903	Transcriptional regulator
Srufu_RS03775	COG3629	intracellular signal transduction
Srufu_RS03780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS03785	COG3251	PFAM MbtH domain protein
Srufu_RS03790	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Srufu_RS03795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS03815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS03925	COG0432	Pfam Uncharacterised protein family UPF0047
Srufu_RS04030	COG0477	Major facilitator Superfamily
Srufu_RS04045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Srufu_RS04050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Srufu_RS04085	COG3415	Transposase
Srufu_RS04085	COG2801	Transposase and inactivated derivatives
Srufu_RS04090	COG1078	dGTPase activity
Srufu_RS04110	COG1132	(ABC) transporter
Srufu_RS04170	COG1819	glycosyl
Srufu_RS04195	COG1946	Acyl-CoA thioesterase
Srufu_RS04205	COG2018	Roadblock/LC7 domain
Srufu_RS04220	COG2226	methyltransferase
Srufu_RS04245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Srufu_RS04260	COG2040	homocysteine
Srufu_RS04265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Srufu_RS04270	COG0765	amino acid transport
Srufu_RS04285	COG3458	cephalosporin-C deacetylase activity
Srufu_RS04305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Srufu_RS04310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Srufu_RS04310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Srufu_RS04315	COG3023	N-Acetylmuramoyl-L-alanine amidase
Srufu_RS04335	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Srufu_RS04335	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Srufu_RS04365	COG0596	Alpha beta hydrolase
Srufu_RS04390	COG0604	alcohol dehydrogenase
Srufu_RS04390	COG3321	synthase
Srufu_RS04400	COG4221	oxidoreductase activity
Srufu_RS04410	COG0445	tRNA wobble uridine modification
Srufu_RS04445	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS04535	COG3360	Dodecin
Srufu_RS04540	COG0531	amino acid
Srufu_RS04565	COG0583	DNA-binding transcription factor activity
Srufu_RS04575	COG3537	Alpha-1,2-mannosidase
Srufu_RS04655	COG2133	pyrroloquinoline quinone binding
Srufu_RS04655	COG5183	chlorophyll binding
Srufu_RS04680	COG2706	6-phosphogluconolactonase activity
Srufu_RS04685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Srufu_RS04705	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS04710	COG1024	Enoyl-CoA hydratase
Srufu_RS04735	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS04750	COG0174	glutamine synthetase
Srufu_RS04765	COG3246	L-lysine catabolic process to acetate
Srufu_RS04770	COG1250	3-hydroxyacyl-CoA dehydrogenase
Srufu_RS04790	COG1686	Belongs to the peptidase S11 family
Srufu_RS04795	COG2124	cytochrome p450
Srufu_RS04830	COG3958	Transketolase
Srufu_RS04835	COG2267	carboxylic ester hydrolase activity
Srufu_RS04840	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS04860	COG2018	Roadblock/LC7 domain
Srufu_RS04900	COG0596	Alpha beta hydrolase
Srufu_RS04910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Srufu_RS04935	COG2755	lipolytic protein G-D-S-L family
Srufu_RS04940	COG2365	Tyrosine phosphatase family
Srufu_RS04965	COG1657	PFAM Prenyltransferase squalene oxidase
Srufu_RS04975	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Srufu_RS04985	COG1562	ergosterol biosynthetic process
Srufu_RS04990	COG1134	teichoic acid transport
Srufu_RS05025	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Srufu_RS05055	COG4977	sequence-specific DNA binding
Srufu_RS05065	COG2183	response to ionizing radiation
Srufu_RS05105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Srufu_RS05190	COG1250	3-hydroxyacyl-CoA dehydrogenase
Srufu_RS05190	COG1024	Enoyl-CoA hydratase
Srufu_RS05195	COG0183	Belongs to the thiolase family
Srufu_RS05200	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS05205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Srufu_RS05220	COG3268	Saccharopine dehydrogenase
Srufu_RS05225	COG1515	deoxyribonuclease V activity
Srufu_RS05230	COG0154	amidase activity
Srufu_RS05240	COG2814	Major facilitator Superfamily
Srufu_RS05245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Srufu_RS05255	COG1349	DNA-binding transcription factor activity
Srufu_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS05265	COG1309	transcriptional regulator
Srufu_RS05275	COG1309	transcriptional regulator
Srufu_RS05280	COG1289	transmembrane transporter activity
Srufu_RS05285	COG1846	Transcriptional regulator
Srufu_RS05300	COG3226	Transcriptional regulator
Srufu_RS05325	COG0745	RESPONSE REGULATOR receiver
Srufu_RS05330	COG2205	protein histidine kinase activity
Srufu_RS05400	COG1309	transcriptional regulator
Srufu_RS05450	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS05455	COG0287	Prephenate dehydrogenase
Srufu_RS05455	COG1605	Chorismate mutase
Srufu_RS05465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Srufu_RS05490	COG0583	DNA-binding transcription factor activity
Srufu_RS05505	COG0656	L-ascorbic acid biosynthetic process
Srufu_RS05515	COG4106	trans-aconitate 2-methyltransferase activity
Srufu_RS05530	COG1295	ribonuclease BN
Srufu_RS05535	COG2154	pterin-4-alpha-carbinolamine dehydratase
Srufu_RS05570	COG0531	amino acid
Srufu_RS05580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Srufu_RS05600	COG0456	acetyltransferase
Srufu_RS05605	COG1597	lipid kinase activity
Srufu_RS05625	COG2207	Transcriptional regulator
Srufu_RS05630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Srufu_RS05655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Srufu_RS05670	COG2124	cytochrome p450
Srufu_RS05685	COG1619	proteins homologs of microcin C7 resistance protein MccF
Srufu_RS05690	COG1506	peptidase
Srufu_RS05690	COG4946	Tricorn protease homolog
Srufu_RS05690	COG0823	Involved in the tonB-independent uptake of proteins
Srufu_RS05700	COG2362	D-Aminopeptidase
Srufu_RS05725	COG2814	Major facilitator Superfamily
Srufu_RS05765	COG1250	3-hydroxyacyl-CoA dehydrogenase
Srufu_RS05780	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Srufu_RS05780	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Srufu_RS05785	COG2301	Belongs to the HpcH HpaI aldolase family
Srufu_RS05795	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS05800	COG0688	phosphatidylethanolamine metabolic process
Srufu_RS05810	COG1929	Belongs to the glycerate kinase type-1 family
Srufu_RS05845	COG0483	inositol monophosphate 1-phosphatase activity
Srufu_RS05860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Srufu_RS05865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Srufu_RS05885	COG1953	Uracil, thiamine, allantoin
Srufu_RS05890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Srufu_RS05895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Srufu_RS05905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Srufu_RS05920	COG1335	isochorismatase
Srufu_RS05930	COG0405	Gamma-glutamyltransferase
Srufu_RS05940	COG0531	amino acid
Srufu_RS05945	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS05965	COG0435	Glutathione S-transferase
Srufu_RS05975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Srufu_RS05980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Srufu_RS05990	COG0765	amino acid transport
Srufu_RS05995	COG0765	amino acid transport
Srufu_RS06000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Srufu_RS06005	COG1126	abc transporter atp-binding protein
Srufu_RS06025	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Srufu_RS06045	COG0667	Aldo Keto reductase
Srufu_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS06075	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS06085	COG1309	transcriptional regulator
Srufu_RS06135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Srufu_RS06220	COG0583	DNA-binding transcription factor activity
Srufu_RS06225	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS06325	COG1396	sequence-specific DNA binding
Srufu_RS06335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Srufu_RS06345	COG0730	response to heat
Srufu_RS06385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Srufu_RS06430	COG3391	amine dehydrogenase activity
Srufu_RS06445	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Srufu_RS06455	COG0110	maltose O-acetyltransferase activity
Srufu_RS06460	COG4257	antibiotic catabolic process
Srufu_RS06470	COG2197	response regulator
Srufu_RS06490	COG2826	transposase and inactivated derivatives, IS30 family
Srufu_RS06510	COG1733	regulation of RNA biosynthetic process
Srufu_RS06520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Srufu_RS06540	COG0657	acetylesterase activity
Srufu_RS06545	COG1733	regulation of RNA biosynthetic process
Srufu_RS06550	COG0702	epimerase
Srufu_RS06645	COG0583	DNA-binding transcription factor activity
Srufu_RS06655	COG0697	spore germination
Srufu_RS06695	COG0076	glutamate decarboxylase activity
Srufu_RS06795	COG1733	regulation of RNA biosynthetic process
Srufu_RS06805	COG2814	Major facilitator Superfamily
Srufu_RS06895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Srufu_RS06920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Srufu_RS06960	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Srufu_RS06970	COG1940	carbohydrate kinase activity
Srufu_RS06980	COG1172	Belongs to the binding-protein-dependent transport system permease family
Srufu_RS06995	COG2188	Transcriptional regulator
Srufu_RS07010	COG0800	Aldolase
Srufu_RS07040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Srufu_RS07055	COG1414	Transcriptional regulator
Srufu_RS07080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Srufu_RS07095	COG0174	glutamine synthetase
Srufu_RS07105	COG1473	amidohydrolase
Srufu_RS07110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Srufu_RS07125	COG2233	PERMEase
Srufu_RS07145	COG2351	hydroxyisourate hydrolase activity
Srufu_RS07165	COG3622	Belongs to the hyi family
Srufu_RS07170	COG2084	Dehydrogenase
Srufu_RS07175	COG0753	catalase activity
Srufu_RS07190	COG2226	methyltransferase
Srufu_RS07195	COG2315	Protein conserved in bacteria
Srufu_RS07235	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS07240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Srufu_RS07245	COG2197	response regulator
Srufu_RS07260	COG0583	DNA-binding transcription factor activity
Srufu_RS07270	COG2318	DinB family
Srufu_RS07285	COG2252	PERMEase
Srufu_RS07290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Srufu_RS07320	COG1802	Transcriptional regulator
Srufu_RS07330	COG4977	sequence-specific DNA binding
Srufu_RS07375	COG0028	Belongs to the TPP enzyme family
Srufu_RS07395	COG1162	GTPase activity
Srufu_RS07400	COG2318	DinB family
Srufu_RS07420	COG1073	alpha beta
Srufu_RS07455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Srufu_RS07455	COG2755	lipolytic protein G-D-S-L family
Srufu_RS07460	COG1215	transferase activity, transferring glycosyl groups
Srufu_RS07470	COG2233	PERMEase
Srufu_RS07475	COG1131	(ABC) transporter
Srufu_RS07475	COG1716	ATPase activity
Srufu_RS07475	COG0842	Transport permease protein
Srufu_RS07505	COG1376	ErfK ybiS ycfS ynhG family protein
Srufu_RS07510	COG0667	Aldo Keto reductase
Srufu_RS07515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Srufu_RS07550	COG3511	phospholipase C
Srufu_RS07555	COG4106	trans-aconitate 2-methyltransferase activity
Srufu_RS07580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Srufu_RS07585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Srufu_RS07590	COG2080	2 iron, 2 sulfur cluster binding
Srufu_RS07620	COG1309	transcriptional regulator
Srufu_RS07665	COG2208	phosphoserine phosphatase activity
Srufu_RS07665	COG2770	Histidine kinase
Srufu_RS07675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Srufu_RS07680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Srufu_RS07685	COG3485	protocatechuate 3,4-dioxygenase
Srufu_RS07690	COG3485	protocatechuate 3,4-dioxygenase
Srufu_RS07695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Srufu_RS07700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Srufu_RS07715	COG2814	Major facilitator Superfamily
Srufu_RS07725	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS07760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Srufu_RS07770	COG0175	sulfate reduction
Srufu_RS07775	COG0529	Catalyzes the synthesis of activated sulfate
Srufu_RS07800	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Srufu_RS07815	COG0366	Alpha amylase catalytic
Srufu_RS07835	COG1609	Transcriptional regulator
Srufu_RS07840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Srufu_RS07845	COG2267	carboxylic ester hydrolase activity
Srufu_RS07880	COG0587	DNA-directed DNA polymerase activity
Srufu_RS07890	COG0577	efflux transmembrane transporter activity
Srufu_RS07890	COG1136	(ABC) transporter
Srufu_RS07895	COG1136	(ABC) transporter
Srufu_RS07900	COG2197	response regulator
Srufu_RS07905	COG4585	Histidine kinase
Srufu_RS07930	COG2318	DinB family
Srufu_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS08020	COG0583	DNA-binding transcription factor activity
Srufu_RS08025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Srufu_RS08045	COG0693	protein deglycase activity
Srufu_RS08055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Srufu_RS08110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Srufu_RS08115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Srufu_RS08120	COG2197	response regulator
Srufu_RS08135	COG1136	(ABC) transporter
Srufu_RS08165	COG1116	anion transmembrane transporter activity
Srufu_RS08195	COG3253	May function as heme-dependent peroxidase
Srufu_RS08200	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Srufu_RS08210	COG0183	Belongs to the thiolase family
Srufu_RS08215	COG0446	pyridine nucleotide-disulphide oxidoreductase
Srufu_RS08225	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Srufu_RS08240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Srufu_RS08250	COG0183	Belongs to the thiolase family
Srufu_RS08255	COG1024	Enoyl-CoA hydratase
Srufu_RS08255	COG1250	3-hydroxyacyl-CoA dehydrogenase
Srufu_RS08275	COG0531	amino acid
Srufu_RS08280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Srufu_RS08285	COG4214	carbohydrate transport
Srufu_RS08295	COG4213	ABC transporter substrate-binding protein
Srufu_RS08305	COG0395	ABC-type sugar transport system, permease component
Srufu_RS08310	COG1175	transmembrane transport
Srufu_RS08315	COG1653	transport
Srufu_RS08325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Srufu_RS08340	COG1595	DNA-templated transcription, initiation
Srufu_RS08345	COG3480	Lon protease (S16) C-terminal proteolytic domain
Srufu_RS08365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Srufu_RS08400	COG0546	phosphoglycolate phosphatase activity
Srufu_RS08430	COG1024	Enoyl-CoA hydratase
Srufu_RS08440	COG0531	amino acid
Srufu_RS08445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Srufu_RS08455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Srufu_RS08485	COG1799	cell septum assembly
Srufu_RS08490	COG0598	Magnesium transport protein CorA
Srufu_RS08495	COG2197	response regulator
Srufu_RS08500	COG4585	Histidine kinase
Srufu_RS08510	COG0596	Alpha beta hydrolase
Srufu_RS08530	COG2124	cytochrome p450
Srufu_RS08535	COG2124	cytochrome p450
Srufu_RS08585	COG1191	sigma factor activity
Srufu_RS08600	COG1191	sigma factor activity
Srufu_RS08615	COG3387	PFAM Glycoside hydrolase 15-related
Srufu_RS08660	COG0477	Major facilitator Superfamily
Srufu_RS08665	COG0302	gtp cyclohydrolase
Srufu_RS08685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Srufu_RS08690	COG4977	sequence-specific DNA binding
Srufu_RS08725	COG0577	efflux transmembrane transporter activity
Srufu_RS08730	COG1136	(ABC) transporter
Srufu_RS08735	COG2205	protein histidine kinase activity
Srufu_RS08740	COG0745	RESPONSE REGULATOR receiver
Srufu_RS08785	COG3695	enzyme binding
Srufu_RS08850	COG1674	ftsk spoiiie
Srufu_RS08970	COG1201	RNA secondary structure unwinding
Srufu_RS08985	COG0531	amino acid
Srufu_RS08995	COG0569	domain protein
Srufu_RS09030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Srufu_RS09035	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Srufu_RS09040	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Srufu_RS09055	COG0756	dUTP diphosphatase activity
Srufu_RS09080	COG2205	protein histidine kinase activity
Srufu_RS09085	COG0745	RESPONSE REGULATOR receiver
Srufu_RS09095	COG0483	inositol monophosphate 1-phosphatase activity
Srufu_RS09100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Srufu_RS09145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS09150	COG3251	PFAM MbtH domain protein
Srufu_RS09160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS09185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Srufu_RS09195	COG1024	Enoyl-CoA hydratase
Srufu_RS09210	COG1024	Enoyl-CoA hydratase
Srufu_RS09220	COG3424	synthase
Srufu_RS09255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Srufu_RS09260	COG1802	Transcriptional regulator
Srufu_RS09275	COG0612	Peptidase, M16
Srufu_RS09280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Srufu_RS09290	COG0372	Belongs to the citrate synthase family
Srufu_RS09305	COG3290	protein histidine kinase activity
Srufu_RS09310	COG4565	transcriptional regulatory protein
Srufu_RS09315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Srufu_RS09325	COG2197	response regulator
Srufu_RS09330	COG4585	Histidine kinase
Srufu_RS09340	COG0187	DNA topoisomerase II activity
Srufu_RS09355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Srufu_RS09360	COG2186	Transcriptional regulator
Srufu_RS09395	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Srufu_RS09425	COG0154	amidase activity
Srufu_RS09430	COG3226	Transcriptional regulator
Srufu_RS09450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Srufu_RS09455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Srufu_RS09460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Srufu_RS09495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Srufu_RS09510	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Srufu_RS09520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Srufu_RS09535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Srufu_RS09545	COG1278	Cold shock
Srufu_RS09550	COG2205	protein histidine kinase activity
Srufu_RS09560	COG1126	abc transporter atp-binding protein
Srufu_RS09565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Srufu_RS09570	COG0765	amino acid transport
Srufu_RS09575	COG0765	amino acid transport
Srufu_RS09580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Srufu_RS09600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Srufu_RS09605	COG0628	permease
Srufu_RS09640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Srufu_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS09655	COG0783	Belongs to the Dps family
Srufu_RS09660	COG1396	sequence-specific DNA binding
Srufu_RS09665	COG1546	Belongs to the CinA family
Srufu_RS09665	COG1058	Belongs to the CinA family
Srufu_RS09675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Srufu_RS09695	COG3437	response regulator, receiver
Srufu_RS09695	COG3850	Histidine kinase
Srufu_RS09695	COG4999	Histidine kinase
Srufu_RS09695	COG2205	protein histidine kinase activity
Srufu_RS09740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Srufu_RS09745	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Srufu_RS09765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Srufu_RS09770	COG0612	Peptidase, M16
Srufu_RS09775	COG1185	polyribonucleotide nucleotidyltransferase activity
Srufu_RS09780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Srufu_RS09790	COG1674	ftsk spoiiie
Srufu_RS09840	COG1404	Belongs to the peptidase S8 family
Srufu_RS09845	COG1404	Belongs to the peptidase S8 family
Srufu_RS09860	COG1404	Belongs to the peptidase S8 family
Srufu_RS09895	COG0596	Alpha beta hydrolase
Srufu_RS09910	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Srufu_RS09915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Srufu_RS09940	COG0779	Required for maturation of 30S ribosomal subunits
Srufu_RS09960	COG0442	prolyl-tRNA aminoacylation
Srufu_RS09975	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Srufu_RS09980	COG0750	zinc metalloprotease
Srufu_RS09985	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Srufu_RS09995	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS10025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Srufu_RS10030	COG1177	transmembrane transport
Srufu_RS10035	COG1176	ABC-type spermidine putrescine transport system, permease component I
Srufu_RS10040	COG3842	ATPase activity
Srufu_RS10050	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS10060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Srufu_RS10070	COG2814	Major facilitator Superfamily
Srufu_RS10075	COG0583	DNA-binding transcription factor activity
Srufu_RS10085	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS10095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Srufu_RS10100	COG4181	ATPase activity
Srufu_RS10120	COG1309	transcriptional regulator
Srufu_RS10135	COG3842	ATPase activity
Srufu_RS10140	COG4208	sulfate ABC transporter
Srufu_RS10150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Srufu_RS10160	COG0575	Belongs to the CDS family
Srufu_RS10165	COG0233	cytoplasmic translational termination
Srufu_RS10170	COG0528	UMP kinase activity
Srufu_RS10175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Srufu_RS10180	COG0052	Belongs to the universal ribosomal protein uS2 family
Srufu_RS10185	COG1388	LysM domain
Srufu_RS10185	COG4942	peptidase
Srufu_RS10195	COG1191	sigma factor activity
Srufu_RS10210	COG0792	nuclease activity
Srufu_RS10225	COG0681	Belongs to the peptidase S26 family
Srufu_RS10230	COG0681	Belongs to the peptidase S26 family
Srufu_RS10240	COG0681	Belongs to the peptidase S26 family
Srufu_RS10245	COG0335	large ribosomal subunit rRNA binding
Srufu_RS10255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Srufu_RS10260	COG1837	Belongs to the UPF0109 family
Srufu_RS10265	COG0228	four-way junction DNA binding
Srufu_RS10285	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Srufu_RS10315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Srufu_RS10325	COG0477	Major facilitator Superfamily
Srufu_RS10340	COG1254	Belongs to the acylphosphatase family
Srufu_RS10345	COG2340	Cysteine-rich secretory protein family
Srufu_RS10355	COG1733	regulation of RNA biosynthetic process
Srufu_RS10360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Srufu_RS10365	COG0571	ribonuclease III activity
Srufu_RS10370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Srufu_RS10385	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Srufu_RS10390	COG0742	ribosomal rna small subunit methyltransferase
Srufu_RS10400	COG1461	Dihydroxyacetone kinase
Srufu_RS10405	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Srufu_RS10410	COG0351	phosphomethylpyrimidine kinase
Srufu_RS10430	COG1181	Belongs to the D-alanine--D-alanine ligase family
Srufu_RS10435	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Srufu_RS10445	COG1920	GTP binding
Srufu_RS10455	COG0776	regulation of translation
Srufu_RS10465	COG0066	3-isopropylmalate dehydratase activity
Srufu_RS10470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Srufu_RS10475	COG1414	Transcriptional regulator
Srufu_RS10510	COG1011	Hydrolase
Srufu_RS10515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Srufu_RS10520	COG0179	Fumarylacetoacetate (FAA) hydrolase
Srufu_RS10535	COG2018	Roadblock/LC7 domain
Srufu_RS10555	COG2018	Roadblock/LC7 domain
Srufu_RS10580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Srufu_RS10585	COG5492	domain, Protein
Srufu_RS10590	COG2353	YceI-like domain
Srufu_RS10600	COG0477	Major facilitator Superfamily
Srufu_RS10610	COG1309	transcriptional regulator
Srufu_RS10615	COG2957	Belongs to the agmatine deiminase family
Srufu_RS10620	COG0804	urea catabolic process
Srufu_RS10625	COG0832	Belongs to the urease beta subunit family
Srufu_RS10625	COG0831	urea catabolic process
Srufu_RS10635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Srufu_RS10640	COG0473	3-isopropylmalate dehydrogenase activity
Srufu_RS10650	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS10655	COG0506	proline dehydrogenase activity
Srufu_RS10675	COG1309	transcriptional regulator
Srufu_RS10685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Srufu_RS10690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Srufu_RS10695	COG0440	acetolactate synthase activity
Srufu_RS10705	COG3300	MHYT domain
Srufu_RS10705	COG5001	Diguanylate cyclase
Srufu_RS10715	COG0667	Aldo Keto reductase
Srufu_RS10720	COG2133	pyrroloquinoline quinone binding
Srufu_RS10730	COG2197	response regulator
Srufu_RS10735	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Srufu_RS10735	COG1672	PFAM Archaeal ATPase
Srufu_RS10755	COG2409	Drug exporters of the RND superfamily
Srufu_RS10760	COG3511	phospholipase C
Srufu_RS10780	COG0667	Aldo Keto reductase
Srufu_RS10790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Srufu_RS10800	COG0154	amidase activity
Srufu_RS10805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Srufu_RS10840	COG4221	oxidoreductase activity
Srufu_RS10850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Srufu_RS10860	COG0482	sulfurtransferase activity
Srufu_RS10890	COG3629	intracellular signal transduction
Srufu_RS10890	COG3903	Transcriptional regulator
Srufu_RS10900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Srufu_RS10920	COG2860	membrane
Srufu_RS10925	COG0308	aminopeptidase N
Srufu_RS10930	COG4608	Belongs to the ABC transporter superfamily
Srufu_RS10935	COG0444	Belongs to the ABC transporter superfamily
Srufu_RS10945	COG0747	negative chemotaxis
Srufu_RS10970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Srufu_RS10975	COG0509	glycine decarboxylation via glycine cleavage system
Srufu_RS10980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Srufu_RS10985	COG1760	l-serine dehydratase
Srufu_RS11015	COG0745	RESPONSE REGULATOR receiver
Srufu_RS11020	COG0438	transferase activity, transferring glycosyl groups
Srufu_RS11030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Srufu_RS11040	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Srufu_RS11045	COG0785	Cytochrome C biogenesis protein
Srufu_RS11050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Srufu_RS11050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Srufu_RS11070	COG1376	ErfK ybiS ycfS ynhG family protein
Srufu_RS11085	COG1132	(ABC) transporter
Srufu_RS11090	COG1132	(ABC) transporter
Srufu_RS11100	COG1132	(ABC) transporter
Srufu_RS11120	COG2197	response regulator
Srufu_RS11125	COG4585	Histidine kinase
Srufu_RS11135	COG0366	Alpha amylase catalytic
Srufu_RS11145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Srufu_RS11150	COG1301	dicarboxylic acid transport
Srufu_RS11155	COG3290	protein histidine kinase activity
Srufu_RS11160	COG4565	transcriptional regulatory protein
Srufu_RS11175	COG0395	ABC-type sugar transport system, permease component
Srufu_RS11185	COG0577	efflux transmembrane transporter activity
Srufu_RS11185	COG1136	(ABC) transporter
Srufu_RS11190	COG0577	efflux transmembrane transporter activity
Srufu_RS11190	COG1136	(ABC) transporter
Srufu_RS11195	COG0205	6-phosphofructokinase activity
Srufu_RS11200	COG0280	phosphate acetyltransferase
Srufu_RS11200	COG0857	belongs to the CobB CobQ family
Srufu_RS11205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Srufu_RS11245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Srufu_RS11250	COG0745	RESPONSE REGULATOR receiver
Srufu_RS11255	COG2205	protein histidine kinase activity
Srufu_RS11260	COG0515	serine threonine protein kinase
Srufu_RS11260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Srufu_RS11265	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Srufu_RS11265	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Srufu_RS11325	COG0745	RESPONSE REGULATOR receiver
Srufu_RS11340	COG0183	Belongs to the thiolase family
Srufu_RS11395	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Srufu_RS11410	COG1250	3-hydroxyacyl-CoA dehydrogenase
Srufu_RS11440	COG2197	response regulator
Srufu_RS11465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS11470	COG0300	oxidoreductase activity
Srufu_RS11470	COG3321	synthase
Srufu_RS11470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS11470	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS11475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS11475	COG3321	synthase
Srufu_RS11475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Srufu_RS11475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS11475	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS11480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS11480	COG3321	synthase
Srufu_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS11480	COG4221	oxidoreductase activity
Srufu_RS11495	COG4221	oxidoreductase activity
Srufu_RS11495	COG0300	oxidoreductase activity
Srufu_RS11495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS11495	COG3321	synthase
Srufu_RS11505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS11505	COG3321	synthase
Srufu_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS11505	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS11505	COG0300	oxidoreductase activity
Srufu_RS11510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Srufu_RS11510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS11510	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS11510	COG3321	synthase
Srufu_RS11510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS11565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS11565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS11565	COG3321	synthase
Srufu_RS11565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Srufu_RS11570	COG1250	3-hydroxyacyl-CoA dehydrogenase
Srufu_RS11585	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS11605	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Srufu_RS11610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Srufu_RS11615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Srufu_RS11620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Srufu_RS11625	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Srufu_RS11630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Srufu_RS11635	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Srufu_RS11655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Srufu_RS11660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Srufu_RS11670	COG2890	protein-(glutamine-N5) methyltransferase activity
Srufu_RS11675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Srufu_RS11680	COG0254	rRNA binding
Srufu_RS11695	COG0083	homoserine kinase activity
Srufu_RS11700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Srufu_RS11705	COG0460	homoserine dehydrogenase
Srufu_RS11710	COG0019	diaminopimelate decarboxylase activity
Srufu_RS11715	COG0018	arginyl-trna synthetase
Srufu_RS11730	COG2124	cytochrome p450
Srufu_RS11745	COG0768	penicillin binding
Srufu_RS11755	COG1119	ATPase activity
Srufu_RS11830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Srufu_RS11835	COG1357	PFAM Pentapeptide repeats (8 copies)
Srufu_RS11880	COG0745	RESPONSE REGULATOR receiver
Srufu_RS11885	COG2205	protein histidine kinase activity
Srufu_RS11890	COG0508	dehydrogenase complex catalyzes the overall conversion of
Srufu_RS11890	COG0567	Dehydrogenase, E1 component
Srufu_RS11915	COG2255	four-way junction helicase activity
Srufu_RS11975	COG0604	alcohol dehydrogenase
Srufu_RS11980	COG0281	malic enzyme
Srufu_RS11995	COG1126	abc transporter atp-binding protein
Srufu_RS12000	COG4106	trans-aconitate 2-methyltransferase activity
Srufu_RS12045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Srufu_RS12050	COG1993	acr, cog1993
Srufu_RS12055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Srufu_RS12065	COG1051	belongs to the nudix hydrolase family
Srufu_RS12070	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Srufu_RS12075	COG0598	Magnesium transport protein CorA
Srufu_RS12115	COG2066	Belongs to the glutaminase family
Srufu_RS12130	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Srufu_RS12165	COG1597	lipid kinase activity
Srufu_RS12180	COG1309	transcriptional regulator
Srufu_RS12185	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS12190	COG0363	glucosamine-6-phosphate deaminase activity
Srufu_RS12195	COG1472	Belongs to the glycosyl hydrolase 3 family
Srufu_RS12200	COG0395	ABC-type sugar transport system, permease component
Srufu_RS12205	COG1175	transmembrane transport
Srufu_RS12210	COG2182	Extracellular solute-binding protein
Srufu_RS12215	COG2188	Transcriptional regulator
Srufu_RS12240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Srufu_RS12245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Srufu_RS12250	COG0242	peptide deformylase activity
Srufu_RS12265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Srufu_RS12265	COG2199	diguanylate cyclase activity
Srufu_RS12270	COG5662	AntiSigma factor
Srufu_RS12275	COG1595	DNA-templated transcription, initiation
Srufu_RS12280	COG1396	sequence-specific DNA binding
Srufu_RS12280	COG3800	Transcriptional regulator
Srufu_RS12290	COG2135	peptidase activity
Srufu_RS12300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Srufu_RS12310	COG2076	Multidrug Resistance protein
Srufu_RS12320	COG0483	inositol monophosphate 1-phosphatase activity
Srufu_RS12325	COG0517	IMP dehydrogenase activity
Srufu_RS12325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Srufu_RS12330	COG0753	catalase activity
Srufu_RS12370	COG1615	UPF0182 protein
Srufu_RS12380	COG3480	Lon protease (S16) C-terminal proteolytic domain
Srufu_RS12435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Srufu_RS12480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Srufu_RS12530	COG0596	Alpha beta hydrolase
Srufu_RS12530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Srufu_RS12565	COG0596	Alpha beta hydrolase
Srufu_RS12575	COG1432	Conserved Protein
Srufu_RS12585	COG2095	MarC family integral membrane protein
Srufu_RS12600	COG2814	Major facilitator Superfamily
Srufu_RS12610	COG0598	Magnesium transport protein CorA
Srufu_RS12665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Srufu_RS12670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Srufu_RS12695	COG1024	Enoyl-CoA hydratase
Srufu_RS12700	COG0519	Catalyzes the synthesis of GMP from XMP
Srufu_RS12710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Srufu_RS12715	COG1611	Belongs to the LOG family
Srufu_RS12720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Srufu_RS12760	COG2197	response regulator
Srufu_RS12765	COG4585	Histidine kinase
Srufu_RS12785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Srufu_RS12805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Srufu_RS12810	COG4166	transmembrane transport
Srufu_RS12815	COG0601	transmembrane transport
Srufu_RS12820	COG0444	Belongs to the ABC transporter superfamily
Srufu_RS12825	COG4608	Belongs to the ABC transporter superfamily
Srufu_RS12830	COG4608	Belongs to the ABC transporter superfamily
Srufu_RS12840	COG0444	Belongs to the ABC transporter superfamily
Srufu_RS12845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Srufu_RS12850	COG0601	transmembrane transport
Srufu_RS12855	COG4166	transmembrane transport
Srufu_RS12860	COG1217	gtp-binding protein TYPA
Srufu_RS12910	COG0531	amino acid
Srufu_RS12940	COG1414	Transcriptional regulator
Srufu_RS12975	COG0012	GTP binding
Srufu_RS12995	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Srufu_RS13005	COG1570	exodeoxyribonuclease VII activity
Srufu_RS13010	COG1722	exodeoxyribonuclease VII activity
Srufu_RS13015	COG0778	Nitroreductase
Srufu_RS13040	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Srufu_RS13040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Srufu_RS13060	COG0114	fumarate hydratase activity
Srufu_RS13085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Srufu_RS13105	COG1136	(ABC) transporter
Srufu_RS13135	COG0450	alkyl hydroperoxide reductase
Srufu_RS13140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Srufu_RS13155	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Srufu_RS13160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Srufu_RS13165	COG0667	Aldo Keto reductase
Srufu_RS13180	COG2885	chlorophyll binding
Srufu_RS13270	COG2610	gluconate transmembrane transporter activity
Srufu_RS13275	COG0251	oxidation-reduction process
Srufu_RS13280	COG1414	Transcriptional regulator
Srufu_RS13285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Srufu_RS13295	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Srufu_RS13315	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Srufu_RS13330	COG0789	Transcriptional regulator
Srufu_RS13335	COG0154	amidase activity
Srufu_RS13345	COG1331	Highly conserved protein containing a thioredoxin domain
Srufu_RS13360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Srufu_RS13370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Srufu_RS13385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Srufu_RS13390	COG2255	four-way junction helicase activity
Srufu_RS13395	COG1595	DNA-templated transcription, initiation
Srufu_RS13415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Srufu_RS13460	COG4221	oxidoreductase activity
Srufu_RS13485	COG4585	Histidine kinase
Srufu_RS13490	COG2197	response regulator
Srufu_RS13495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Srufu_RS13510	COG0454	-acetyltransferase
Srufu_RS13510	COG0456	acetyltransferase
Srufu_RS13530	COG2986	histidine ammonia-lyase
Srufu_RS13540	COG1024	Enoyl-CoA hydratase
Srufu_RS13545	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Srufu_RS13555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Srufu_RS13565	COG0768	penicillin binding
Srufu_RS13580	COG0693	protein deglycase activity
Srufu_RS13590	COG4770	biotin carboxylase activity
Srufu_RS13635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Srufu_RS13640	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS13670	COG0745	RESPONSE REGULATOR receiver
Srufu_RS13675	COG2205	protein histidine kinase activity
Srufu_RS13700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Srufu_RS13710	COG0583	DNA-binding transcription factor activity
Srufu_RS13715	COG2814	Major facilitator Superfamily
Srufu_RS13795	COG1079	Belongs to the binding-protein-dependent transport system permease family
Srufu_RS13800	COG4603	Belongs to the binding-protein-dependent transport system permease family
Srufu_RS13805	COG3845	ABC transporter
Srufu_RS13810	COG1744	ABC transporter substrate-binding protein PnrA-like
Srufu_RS13815	COG1473	amidohydrolase
Srufu_RS13815	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Srufu_RS13825	COG2089	acid synthase
Srufu_RS13830	COG1083	cytidylyl-transferase
Srufu_RS13840	COG1216	Glycosyl transferase, family 2
Srufu_RS13850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Srufu_RS13870	COG3265	gluconokinase activity
Srufu_RS13905	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Srufu_RS13915	COG2009	succinate dehydrogenase
Srufu_RS13925	COG1053	succinate dehydrogenase
Srufu_RS13930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Srufu_RS13970	COG1686	Belongs to the peptidase S11 family
Srufu_RS13975	COG1295	ribonuclease BN
Srufu_RS13985	COG0180	Tryptophanyl-tRNA synthetase
Srufu_RS13990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Srufu_RS13995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Srufu_RS14040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Srufu_RS14050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Srufu_RS14065	COG0640	Transcriptional regulator
Srufu_RS14095	COG0517	IMP dehydrogenase activity
Srufu_RS14095	COG4175	Glycine betaine
Srufu_RS14105	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS14190	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Srufu_RS14235	COG0045	succinate-CoA ligase (ADP-forming) activity
Srufu_RS14255	COG3552	Protein containing von Willebrand factor type A (VWA) domain
Srufu_RS14265	COG0714	Associated with various cellular activities
Srufu_RS14280	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Srufu_RS14310	COG0791	NLP P60 protein
Srufu_RS14320	COG2197	response regulator
Srufu_RS14330	COG2815	serine threonine protein kinase
Srufu_RS14330	COG0515	serine threonine protein kinase
Srufu_RS14375	COG2423	ornithine cyclodeaminase activity
Srufu_RS14380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Srufu_RS14390	COG0519	Catalyzes the synthesis of GMP from XMP
Srufu_RS14390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Srufu_RS14430	COG2814	Major facilitator Superfamily
Srufu_RS14440	COG4585	Histidine kinase
Srufu_RS14445	COG1366	Belongs to the anti-sigma-factor antagonist family
Srufu_RS14510	COG2945	thiolester hydrolase activity
Srufu_RS14510	COG0596	Alpha beta hydrolase
Srufu_RS14520	COG4821	SIS domain
Srufu_RS14530	COG0259	pyridoxamine-phosphate oxidase activity
Srufu_RS14565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Srufu_RS14585	COG5006	permease, DMT superfamily
Srufu_RS14590	COG0583	DNA-binding transcription factor activity
Srufu_RS14620	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Srufu_RS14665	COG0667	Aldo Keto reductase
Srufu_RS14675	COG0477	Major facilitator Superfamily
Srufu_RS14695	COG2252	PERMEase
Srufu_RS14705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Srufu_RS14725	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Srufu_RS14775	COG2814	Major facilitator Superfamily
Srufu_RS14785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Srufu_RS14790	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Srufu_RS14795	COG1278	Cold shock
Srufu_RS14830	COG1061	Type III restriction enzyme res subunit
Srufu_RS14845	COG3973	AAA domain
Srufu_RS14890	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Srufu_RS14895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Srufu_RS14895	COG1263	PTS System
Srufu_RS14900	COG0745	RESPONSE REGULATOR receiver
Srufu_RS14925	COG0459	protein refolding
Srufu_RS14930	COG1278	Cold shock
Srufu_RS14945	COG0463	Glycosyl transferase, family 2
Srufu_RS14955	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Srufu_RS15005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Srufu_RS15020	COG2197	response regulator
Srufu_RS15065	COG0745	RESPONSE REGULATOR receiver
Srufu_RS15075	COG2205	protein histidine kinase activity
Srufu_RS15095	COG3842	ATPase activity
Srufu_RS15120	COG0215	cysteine-tRNA ligase activity
Srufu_RS15130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Srufu_RS15135	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Srufu_RS15140	COG1329	Transcriptional regulator
Srufu_RS15155	COG5002	protein histidine kinase activity
Srufu_RS15170	COG0588	phosphoglycerate mutase activity
Srufu_RS15185	COG0438	transferase activity, transferring glycosyl groups
Srufu_RS15200	COG0667	Aldo Keto reductase
Srufu_RS15230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Srufu_RS15245	COG0456	acetyltransferase
Srufu_RS15250	COG0737	Belongs to the 5'-nucleotidase family
Srufu_RS15290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Srufu_RS15295	COG1609	Transcriptional regulator
Srufu_RS15300	COG0745	RESPONSE REGULATOR receiver
Srufu_RS15330	COG2897	thiosulfate sulfurtransferase activity
Srufu_RS15350	COG3485	protocatechuate 3,4-dioxygenase
Srufu_RS15355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Srufu_RS15360	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Srufu_RS15370	COG0735	belongs to the Fur family
Srufu_RS15380	COG1490	D-aminoacyl-tRNA deacylase activity
Srufu_RS15400	COG0431	NADPH-dependent FMN reductase
Srufu_RS15415	COG4106	trans-aconitate 2-methyltransferase activity
Srufu_RS15415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Srufu_RS15430	COG0667	Aldo Keto reductase
Srufu_RS15445	COG2890	protein-(glutamine-N5) methyltransferase activity
Srufu_RS15475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Srufu_RS15490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Srufu_RS15495	COG0306	phosphate transporter
Srufu_RS15505	COG1937	Protein conserved in bacteria
Srufu_RS15525	COG0277	FAD linked oxidase domain protein
Srufu_RS15530	COG0671	phosphoesterase, PA-phosphatase related
Srufu_RS15535	COG1196	nuclear chromosome segregation
Srufu_RS15535	COG0741	lytic transglycosylase activity
Srufu_RS15535	COG0739	heme binding
Srufu_RS15590	COG0180	Tryptophanyl-tRNA synthetase
Srufu_RS15600	COG0842	Transport permease protein
Srufu_RS15600	COG1129	ABC transporter
Srufu_RS15625	COG1252	NADH dehydrogenase
Srufu_RS15630	COG1595	DNA-templated transcription, initiation
Srufu_RS15655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Srufu_RS15655	COG0515	serine threonine protein kinase
Srufu_RS15675	COG0129	dihydroxy-acid dehydratase activity
Srufu_RS15685	COG1082	Xylose isomerase domain protein TIM barrel
Srufu_RS15690	COG0248	Ppx GppA phosphatase
Srufu_RS15715	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Srufu_RS15755	COG1194	a g-specific adenine glycosylase
Srufu_RS15760	COG1595	DNA-templated transcription, initiation
Srufu_RS15770	COG0745	RESPONSE REGULATOR receiver
Srufu_RS15775	COG2205	protein histidine kinase activity
Srufu_RS15790	COG0739	heme binding
Srufu_RS15815	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Srufu_RS15830	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Srufu_RS15840	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Srufu_RS15855	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Srufu_RS15865	COG0640	Transcriptional regulator
Srufu_RS15875	COG4585	Histidine kinase
Srufu_RS15885	COG0649	NAD binding
Srufu_RS15890	COG3226	Transcriptional regulator
Srufu_RS15910	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Srufu_RS15915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Srufu_RS15940	COG0302	gtp cyclohydrolase
Srufu_RS15965	COG2027	D-alanyl-D-alanine carboxypeptidase
Srufu_RS15970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Srufu_RS15985	COG0393	Putative heavy-metal-binding
Srufu_RS15990	COG0789	Transcriptional regulator
Srufu_RS16000	COG0655	NAD(P)H dehydrogenase (quinone) activity
Srufu_RS16005	COG0076	glutamate decarboxylase activity
Srufu_RS16015	COG2318	DinB family
Srufu_RS16020	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS16040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Srufu_RS16050	COG0254	rRNA binding
Srufu_RS16055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Srufu_RS16060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Srufu_RS16065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Srufu_RS16075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Srufu_RS16075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Srufu_RS16130	COG1309	transcriptional regulator
Srufu_RS16145	COG3594	Acyltransferase
Srufu_RS16150	COG0584	glycerophosphoryl diester phosphodiesterase
Srufu_RS16155	COG2197	response regulator
Srufu_RS16175	COG0745	RESPONSE REGULATOR receiver
Srufu_RS16180	COG2205	protein histidine kinase activity
Srufu_RS16210	COG3903	Transcriptional regulator
Srufu_RS16210	COG3629	intracellular signal transduction
Srufu_RS16215	COG2124	cytochrome p450
Srufu_RS16230	COG0475	glutathione-regulated potassium exporter activity
Srufu_RS16250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Srufu_RS16255	COG3251	PFAM MbtH domain protein
Srufu_RS16260	COG2175	clavaminate synthase activity
Srufu_RS16325	COG0644	oxidoreductase
Srufu_RS16370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Srufu_RS16380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Srufu_RS16380	COG1754	DNA topoisomerase type I activity
Srufu_RS16405	COG2890	protein-(glutamine-N5) methyltransferase activity
Srufu_RS16415	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Srufu_RS16420	COG2172	sigma factor antagonist activity
Srufu_RS16425	COG1366	Belongs to the anti-sigma-factor antagonist family
Srufu_RS16490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Srufu_RS16495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Srufu_RS16505	COG2267	carboxylic ester hydrolase activity
Srufu_RS16535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Srufu_RS16560	COG0003	Pfam Anion-transporting ATPase
Srufu_RS16570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Srufu_RS16580	COG1408	metallophosphoesterase
Srufu_RS16595	COG4249	Peptidase C14 caspase catalytic subunit p20
Srufu_RS16595	COG2319	Wd-40 repeat
Srufu_RS16600	COG2188	Transcriptional regulator
Srufu_RS16610	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Srufu_RS16630	COG1316	TRANSCRIPTIONal
Srufu_RS16635	COG1215	transferase activity, transferring glycosyl groups
Srufu_RS16640	COG1309	transcriptional regulator
Srufu_RS16645	COG2124	cytochrome p450
Srufu_RS16675	COG1595	DNA-templated transcription, initiation
Srufu_RS16695	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Srufu_RS16700	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Srufu_RS16760	COG2255	four-way junction helicase activity
Srufu_RS16825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Srufu_RS16845	COG0515	serine threonine protein kinase
Srufu_RS16845	COG2815	serine threonine protein kinase
Srufu_RS16870	COG2197	response regulator
Srufu_RS16910	COG0531	amino acid
Srufu_RS16915	COG1132	(ABC) transporter
Srufu_RS16920	COG1136	(ABC) transporter
Srufu_RS16920	COG0577	efflux transmembrane transporter activity
Srufu_RS16925	COG0577	efflux transmembrane transporter activity
Srufu_RS16925	COG1136	(ABC) transporter
Srufu_RS16940	COG0745	RESPONSE REGULATOR receiver
Srufu_RS16945	COG2205	protein histidine kinase activity
Srufu_RS16975	COG2197	response regulator
Srufu_RS16985	COG1136	(ABC) transporter
Srufu_RS17000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Srufu_RS17010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Srufu_RS17035	COG0189	ligase activity
Srufu_RS17050	COG1834	amidinotransferase
Srufu_RS17055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Srufu_RS17080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Srufu_RS17085	COG2226	methyltransferase
Srufu_RS17095	COG2268	Band 7 protein
Srufu_RS17130	COG1064	alcohol dehydrogenase
Srufu_RS17140	COG0523	cobalamin synthesis protein
Srufu_RS17175	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Srufu_RS17195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Srufu_RS17235	COG1191	sigma factor activity
Srufu_RS17240	COG1191	sigma factor activity
Srufu_RS17260	COG0402	S-adenosylhomocysteine deaminase activity
Srufu_RS17275	COG0477	Major facilitator Superfamily
Srufu_RS17280	COG2353	YceI-like domain
Srufu_RS17290	COG0477	Major facilitator Superfamily
Srufu_RS17305	COG2205	protein histidine kinase activity
Srufu_RS17310	COG0745	RESPONSE REGULATOR receiver
Srufu_RS17315	COG1132	(ABC) transporter
Srufu_RS17320	COG0431	NADPH-dependent FMN reductase
Srufu_RS17320	COG3976	FMN-binding domain protein
Srufu_RS17320	COG1053	succinate dehydrogenase
Srufu_RS17340	COG2249	NAD(P)H dehydrogenase (quinone) activity
Srufu_RS17380	COG2188	Transcriptional regulator
Srufu_RS17470	COG0784	Response regulator, receiver
Srufu_RS17475	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS17545	COG0662	Cupin 2, conserved barrel domain protein
Srufu_RS17560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Srufu_RS17565	COG1595	DNA-templated transcription, initiation
Srufu_RS17580	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS17590	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS17615	COG5632	N-Acetylmuramoyl-L-alanine amidase
Srufu_RS17615	COG3409	Peptidoglycan-binding domain 1 protein
Srufu_RS17655	COG0653	protein targeting
Srufu_RS17675	COG0006	proline dipeptidase activity
Srufu_RS17725	COG2372	response to copper ion
Srufu_RS17730	COG2837	iron assimilation
Srufu_RS17740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Srufu_RS17745	COG0561	phosphatase activity
Srufu_RS17785	COG2186	Transcriptional regulator
Srufu_RS17790	COG2807	transmembrane transport
Srufu_RS17795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Srufu_RS17815	COG1131	(ABC) transporter
Srufu_RS17830	COG0789	Transcriptional regulator
Srufu_RS17835	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Srufu_RS17845	COG0501	Belongs to the peptidase M48B family
Srufu_RS17855	COG0561	phosphatase activity
Srufu_RS17865	COG4988	ABC transporter
Srufu_RS17870	COG1294	oxidase, subunit
Srufu_RS17875	COG1271	oxidase subunit
Srufu_RS17880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Srufu_RS17885	COG1609	Transcriptional regulator
Srufu_RS17890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Srufu_RS17900	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Srufu_RS17925	COG0662	Cupin 2, conserved barrel domain protein
Srufu_RS17930	COG1950	PFAM Membrane protein of
Srufu_RS17935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Srufu_RS17940	COG0626	cystathionine gamma-synthase activity
Srufu_RS17980	COG2814	Major facilitator Superfamily
Srufu_RS18015	COG0789	Transcriptional regulator
Srufu_RS18015	COG4978	Transcriptional regulator
Srufu_RS18020	COG4977	sequence-specific DNA binding
Srufu_RS18045	COG0305	Participates in initiation and elongation during chromosome replication
Srufu_RS18050	COG0534	Mate efflux family protein
Srufu_RS18060	COG0359	binds to the 23S rRNA
Srufu_RS18065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Srufu_RS18070	COG0629	single-stranded DNA binding
Srufu_RS18075	COG0360	Binds together with S18 to 16S ribosomal RNA
Srufu_RS18125	COG0617	tRNA 3'-terminal CCA addition
Srufu_RS18135	COG0728	peptidoglycan biosynthetic process
Srufu_RS18140	COG0515	serine threonine protein kinase
Srufu_RS18140	COG2815	serine threonine protein kinase
Srufu_RS18150	COG1595	DNA-templated transcription, initiation
Srufu_RS18160	COG0492	ferredoxin-NADP+ reductase activity
Srufu_RS18165	COG3118	belongs to the thioredoxin family
Srufu_RS18180	COG1192	Involved in chromosome partitioning
Srufu_RS18185	COG0357	Ribosomal RNA small subunit methyltransferase G
Srufu_RS18190	COG1847	R3H domain protein
Srufu_RS18195	COG0706	membrane insertase activity
Srufu_RS18200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Srufu_RS18210	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Srufu_RS18220	COG0592	DNA-directed DNA polymerase activity
Srufu_RS18225	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Srufu_RS18230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Srufu_RS18235	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Srufu_RS18240	COG0187	DNA topoisomerase II activity
Srufu_RS18245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Srufu_RS18275	COG0515	serine threonine protein kinase
Srufu_RS18300	COG0705	Rhomboid family
Srufu_RS18315	COG3764	Sortase (surface protein transpeptidase)
Srufu_RS18335	COG3764	Sortase (surface protein transpeptidase)
Srufu_RS18340	COG0515	serine threonine protein kinase
Srufu_RS18360	COG1716	ATPase activity
Srufu_RS18375	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Srufu_RS18380	COG1733	regulation of RNA biosynthetic process
Srufu_RS18415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Srufu_RS18420	COG2151	metal-sulfur cluster biosynthetic enzyme
Srufu_RS18425	COG3396	Phenylacetate-CoA oxygenase
Srufu_RS18430	COG3460	Phenylacetate-CoA oxygenase
Srufu_RS18435	COG3396	Phenylacetate-CoA oxygenase
Srufu_RS18465	COG1309	transcriptional regulator
Srufu_RS18470	COG1522	sequence-specific DNA binding
Srufu_RS18605	COG0515	serine threonine protein kinase
Srufu_RS18630	COG0022	dehydrogenase e1 component
Srufu_RS18635	COG0508	dehydrogenase complex catalyzes the overall conversion of
Srufu_RS18655	COG0456	acetyltransferase
Srufu_RS18695	COG3903	Transcriptional regulator
Srufu_RS18695	COG3629	intracellular signal transduction
Srufu_RS18700	COG1362	aminopeptidase activity
Srufu_RS18705	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS18745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Srufu_RS18755	COG2304	oxidoreductase activity
Srufu_RS18780	COG1174	glycine betaine transport
Srufu_RS18785	COG1174	glycine betaine transport
Srufu_RS18790	COG1732	Glycine betaine
Srufu_RS18800	COG0745	RESPONSE REGULATOR receiver
Srufu_RS18850	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Srufu_RS18905	COG1316	TRANSCRIPTIONal
Srufu_RS18960	COG2197	response regulator
Srufu_RS19010	COG2815	serine threonine protein kinase
Srufu_RS19010	COG0515	serine threonine protein kinase
Srufu_RS19045	COG2815	serine threonine protein kinase
Srufu_RS19045	COG0515	serine threonine protein kinase
Srufu_RS19050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Srufu_RS19075	COG2076	Multidrug Resistance protein
Srufu_RS19130	COG0302	gtp cyclohydrolase
Srufu_RS19190	COG2755	lipolytic protein G-D-S-L family
Srufu_RS19210	COG2181	nitrate reductase activity
Srufu_RS19210	COG0247	lactate metabolic process
Srufu_RS19215	COG0443	Heat shock 70 kDa protein
Srufu_RS19220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Srufu_RS19225	COG0484	heat shock protein binding
Srufu_RS19230	COG0789	Transcriptional regulator
Srufu_RS19275	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Srufu_RS19290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Srufu_RS19295	COG0191	fructose-bisphosphate aldolase activity
Srufu_RS19310	COG3483	tryptophan 2,3-dioxygenase activity
Srufu_RS19330	COG2197	response regulator
Srufu_RS19355	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Srufu_RS19380	COG0693	protein deglycase activity
Srufu_RS19385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Srufu_RS19390	COG1802	Transcriptional regulator
Srufu_RS19405	COG0151	Belongs to the GarS family
Srufu_RS19420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Srufu_RS19430	COG2197	response regulator
Srufu_RS19465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Srufu_RS19470	COG0047	phosphoribosylformylglycinamidine synthase activity
Srufu_RS19475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Srufu_RS19500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Srufu_RS19530	COG1643	Atp-dependent helicase
Srufu_RS19570	COG0513	Belongs to the DEAD box helicase family
Srufu_RS19605	COG2826	transposase and inactivated derivatives, IS30 family
Srufu_RS19645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Srufu_RS19655	COG0579	oxidoreductase
Srufu_RS19680	COG1252	NADH dehydrogenase
Srufu_RS19695	COG1846	Transcriptional regulator
Srufu_RS19715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Srufu_RS19725	COG0123	including yeast histone deacetylase and acetoin utilization protein
Srufu_RS19775	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Srufu_RS19780	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Srufu_RS19785	COG0181	hydroxymethylbilane synthase activity
Srufu_RS19790	COG1648	precorrin-2 dehydrogenase activity
Srufu_RS19790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Srufu_RS19795	COG0113	porphobilinogen synthase activity
Srufu_RS19800	COG3237	CsbD-like
Srufu_RS19810	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Srufu_RS19835	COG1690	Belongs to the RtcB family
Srufu_RS19840	COG1714	RDD family
Srufu_RS19860	COG1742	UPF0060 membrane protein
Srufu_RS19870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Srufu_RS19905	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Srufu_RS19910	COG0406	alpha-ribazole phosphatase activity
Srufu_RS19925	COG0785	Cytochrome C biogenesis protein
Srufu_RS19935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Srufu_RS19960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Srufu_RS19980	COG0163	prenyltransferase activity
Srufu_RS19990	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Srufu_RS20005	COG1301	dicarboxylic acid transport
Srufu_RS20015	COG1309	transcriptional regulator
Srufu_RS20025	COG2124	cytochrome p450
Srufu_RS20030	COG2226	methyltransferase
Srufu_RS20040	COG1278	Cold shock
Srufu_RS20045	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Srufu_RS20055	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Srufu_RS20065	COG2226	methyltransferase
Srufu_RS20105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Srufu_RS20110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Srufu_RS20115	COG0649	NAD binding
Srufu_RS20125	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Srufu_RS20130	COG1034	ATP synthesis coupled electron transport
Srufu_RS20135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Srufu_RS20140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Srufu_RS20150	COG0713	ATP synthesis coupled electron transport
Srufu_RS20155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Srufu_RS20165	COG1007	ATP synthesis coupled electron transport
Srufu_RS20190	COG0142	geranyltranstransferase activity
Srufu_RS20215	COG0702	epimerase
Srufu_RS20220	COG1013	pyruvate-flavodoxin oxidoreductase activity
Srufu_RS20225	COG0674	pyruvate-flavodoxin oxidoreductase activity
Srufu_RS20225	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Srufu_RS20235	COG4585	Histidine kinase
Srufu_RS20240	COG4585	Histidine kinase
Srufu_RS20260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Srufu_RS20265	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Srufu_RS20270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Srufu_RS20275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Srufu_RS20280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Srufu_RS20285	COG0839	Belongs to the complex I subunit 6 family
Srufu_RS20290	COG0713	ATP synthesis coupled electron transport
Srufu_RS20305	COG1007	ATP synthesis coupled electron transport
Srufu_RS20310	COG0501	Belongs to the peptidase M48B family
Srufu_RS20315	COG3304	Inner membrane component domain
Srufu_RS20320	COG1666	GTP binding
Srufu_RS20330	COG0702	epimerase
Srufu_RS20350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Srufu_RS20355	COG2030	dehydratase
Srufu_RS20365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Srufu_RS20370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Srufu_RS20375	COG0436	Aminotransferase
Srufu_RS20390	COG0250	Participates in transcription elongation, termination and antitermination
Srufu_RS20395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Srufu_RS20400	COG0081	regulation of translation
Srufu_RS20405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Srufu_RS20410	COG0222	ribosome binding
Srufu_RS20415	COG0085	RNA polymerase activity
Srufu_RS20420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Srufu_RS20430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Srufu_RS20435	COG0049	tRNA binding
Srufu_RS20440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Srufu_RS20445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Srufu_RS20450	COG0051	transcription antitermination factor activity, RNA binding
Srufu_RS20455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Srufu_RS20460	COG0088	Forms part of the polypeptide exit tunnel
Srufu_RS20465	COG0089	rRNA binding
Srufu_RS20470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Srufu_RS20475	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Srufu_RS20480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Srufu_RS20490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Srufu_RS20495	COG0255	Belongs to the universal ribosomal protein uL29 family
Srufu_RS20500	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Srufu_RS20505	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Srufu_RS20510	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Srufu_RS20515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Srufu_RS20520	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Srufu_RS20525	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Srufu_RS20530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Srufu_RS20535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Srufu_RS20540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Srufu_RS20545	COG1841	ribosomal large subunit assembly
Srufu_RS20570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Srufu_RS20575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Srufu_RS20580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Srufu_RS20585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Srufu_RS20590	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Srufu_RS20595	COG0202	RNA polymerase activity
Srufu_RS20605	COG0101	tRNA pseudouridine synthase activity
Srufu_RS20615	COG0488	(ABC) transporter
Srufu_RS20620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Srufu_RS20625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Srufu_RS20630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Srufu_RS20640	COG1072	(Pantothenic acid kinase))
Srufu_RS20655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Srufu_RS20660	COG0736	holo-[acyl-carrier-protein] synthase activity
Srufu_RS20685	COG0802	atpase or kinase
Srufu_RS20710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Srufu_RS20730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Srufu_RS20745	COG4221	oxidoreductase activity
Srufu_RS20755	COG0583	DNA-binding transcription factor activity
Srufu_RS20770	COG1595	DNA-templated transcription, initiation
Srufu_RS20780	COG0516	GMP reductase activity
Srufu_RS20790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Srufu_RS20815	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS20820	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS20870	COG1024	Enoyl-CoA hydratase
Srufu_RS20890	COG0259	pyridoxamine-phosphate oxidase activity
Srufu_RS20920	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS20935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Srufu_RS20935	COG0515	serine threonine protein kinase
Srufu_RS20950	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Srufu_RS21015	COG2319	Wd-40 repeat
Srufu_RS21025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Srufu_RS21040	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Srufu_RS21065	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Srufu_RS21095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Srufu_RS21120	COG1686	Belongs to the peptidase S11 family
Srufu_RS21145	COG0514	ATP-dependent DNA helicase (RecQ)
Srufu_RS21150	COG0154	amidase activity
Srufu_RS21160	COG2197	response regulator
Srufu_RS21200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS21215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Srufu_RS21220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS21230	COG2423	ornithine cyclodeaminase activity
Srufu_RS21270	COG1131	(ABC) transporter
Srufu_RS21280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS21295	COG3903	Transcriptional regulator
Srufu_RS21295	COG3629	intracellular signal transduction
Srufu_RS21335	COG1309	transcriptional regulator
Srufu_RS21355	COG1846	Transcriptional regulator
Srufu_RS21380	COG1247	-acetyltransferase
Srufu_RS21390	COG1349	DNA-binding transcription factor activity
Srufu_RS21395	COG1105	Belongs to the carbohydrate kinase PfkB family
Srufu_RS21400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Srufu_RS21400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Srufu_RS21400	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Srufu_RS21425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Srufu_RS21490	COG2188	Transcriptional regulator
Srufu_RS21500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Srufu_RS21525	COG1970	mechanosensitive ion channel activity
Srufu_RS21530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Srufu_RS21545	COG3263	regulation of cellular component size
Srufu_RS21555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Srufu_RS21560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Srufu_RS21570	COG0315	cyclic pyranopterin monophosphate synthase activity
Srufu_RS21575	COG0521	Mo-molybdopterin cofactor biosynthetic process
Srufu_RS21575	COG0315	cyclic pyranopterin monophosphate synthase activity
Srufu_RS21610	COG0789	Transcriptional regulator
Srufu_RS21615	COG1725	Transcriptional regulator
Srufu_RS21635	COG0708	Exodeoxyribonuclease III
Srufu_RS21645	COG3903	Transcriptional regulator
Srufu_RS21645	COG3629	intracellular signal transduction
Srufu_RS21650	COG0789	Transcriptional regulator
Srufu_RS21655	COG2072	flavoprotein involved in K transport
Srufu_RS21660	COG2267	carboxylic ester hydrolase activity
Srufu_RS21665	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS21675	COG0793	Belongs to the peptidase S41A family
Srufu_RS21675	COG4946	Tricorn protease homolog
Srufu_RS21690	COG0310	cobalt ion transport
Srufu_RS21700	COG1122	ATPase activity
Srufu_RS21725	COG1090	epimerase
Srufu_RS21755	COG0084	hydrolase, TatD family'
Srufu_RS21770	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Srufu_RS21810	COG0488	(ABC) transporter
Srufu_RS21845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Srufu_RS21850	COG2197	response regulator
Srufu_RS21860	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS21870	COG4106	trans-aconitate 2-methyltransferase activity
Srufu_RS21875	COG1309	transcriptional regulator
Srufu_RS21885	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Srufu_RS21895	COG0193	aminoacyl-tRNA hydrolase activity
Srufu_RS21900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Srufu_RS21905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Srufu_RS21910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Srufu_RS21920	COG4585	Histidine kinase
Srufu_RS21945	COG1316	TRANSCRIPTIONal
Srufu_RS21955	COG2814	Major facilitator Superfamily
Srufu_RS21980	COG2814	Major facilitator Superfamily
Srufu_RS21990	COG2124	cytochrome p450
Srufu_RS22005	COG0148	phosphopyruvate hydratase activity
Srufu_RS22030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Srufu_RS22040	COG1136	(ABC) transporter
Srufu_RS22040	COG0577	efflux transmembrane transporter activity
Srufu_RS22050	COG0297	glycogen (starch) synthase activity
Srufu_RS22055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Srufu_RS22080	COG0183	Belongs to the thiolase family
Srufu_RS22085	COG2755	lipolytic protein G-D-S-L family
Srufu_RS22100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Srufu_RS22115	COG1609	Transcriptional regulator
Srufu_RS22135	COG1174	glycine betaine transport
Srufu_RS22140	COG1174	glycine betaine transport
Srufu_RS22185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Srufu_RS22190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Srufu_RS22200	COG1228	amidohydrolase
Srufu_RS22205	COG1191	sigma factor activity
Srufu_RS22250	COG2205	protein histidine kinase activity
Srufu_RS22290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Srufu_RS22300	COG1316	TRANSCRIPTIONal
Srufu_RS22320	COG1316	TRANSCRIPTIONal
Srufu_RS22335	COG1316	TRANSCRIPTIONal
Srufu_RS22355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Srufu_RS22365	COG0778	Nitroreductase
Srufu_RS22365	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
Srufu_RS22370	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Srufu_RS22410	COG2835	tetraacyldisaccharide 4'-kinase activity
Srufu_RS22435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Srufu_RS22435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Srufu_RS22435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Srufu_RS22440	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Srufu_RS22480	COG0714	Associated with various cellular activities
Srufu_RS22500	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Srufu_RS22505	COG0745	RESPONSE REGULATOR receiver
Srufu_RS22510	COG5000	phosphorelay sensor kinase activity
Srufu_RS22510	COG5002	protein histidine kinase activity
Srufu_RS22515	COG0823	Involved in the tonB-independent uptake of proteins
Srufu_RS22525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Srufu_RS22530	COG2197	response regulator
Srufu_RS22535	COG3214	Protein conserved in bacteria
Srufu_RS22545	COG0653	protein targeting
Srufu_RS22560	COG0546	phosphoglycolate phosphatase activity
Srufu_RS22570	COG1134	teichoic acid transport
Srufu_RS22580	COG1309	transcriptional regulator
Srufu_RS22585	COG0463	Glycosyl transferase, family 2
Srufu_RS22585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Srufu_RS22605	COG2226	methyltransferase
Srufu_RS22620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Srufu_RS22635	COG0395	ABC-type sugar transport system, permease component
Srufu_RS22640	COG1175	transmembrane transport
Srufu_RS22645	COG1653	transport
Srufu_RS22655	COG0515	serine threonine protein kinase
Srufu_RS22660	COG0515	serine threonine protein kinase
Srufu_RS22665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Srufu_RS22680	COG2884	Cell division ATP-binding protein ftsE
Srufu_RS22685	COG2177	Part of the ABC transporter FtsEX involved in
Srufu_RS22690	COG0793	Belongs to the peptidase S41A family
Srufu_RS22695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Srufu_RS22710	COG0583	DNA-binding transcription factor activity
Srufu_RS22730	COG2223	nitrite transmembrane transporter activity
Srufu_RS22760	COG3973	AAA domain
Srufu_RS22770	COG0776	regulation of translation
Srufu_RS22780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Srufu_RS22785	COG1678	Uncharacterized ACR, COG1678
Srufu_RS22815	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Srufu_RS22835	COG0596	Alpha beta hydrolase
Srufu_RS22865	COG1174	glycine betaine transport
Srufu_RS22875	COG1174	glycine betaine transport
Srufu_RS22885	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Srufu_RS22890	COG0277	FAD linked oxidase domain protein
Srufu_RS22900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Srufu_RS22900	COG2080	2 iron, 2 sulfur cluster binding
Srufu_RS22915	COG0222	ribosome binding
Srufu_RS22920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Srufu_RS22955	COG1335	isochorismatase
Srufu_RS22965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Srufu_RS22975	COG1113	amino acid transport
Srufu_RS23000	COG1234	tRNA 3'-trailer cleavage
Srufu_RS23005	COG1263	PTS System
Srufu_RS23015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Srufu_RS23020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Srufu_RS23035	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Srufu_RS23055	COG0477	Major facilitator Superfamily
Srufu_RS23065	COG2205	protein histidine kinase activity
Srufu_RS23080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Srufu_RS23090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Srufu_RS23120	COG2733	membrane
Srufu_RS23125	COG3764	Sortase (surface protein transpeptidase)
Srufu_RS23135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Srufu_RS23185	COG0179	Fumarylacetoacetate (FAA) hydrolase
Srufu_RS23195	COG4702	Belongs to the UPF0303 family
Srufu_RS23200	COG0673	inositol 2-dehydrogenase activity
Srufu_RS23265	COG1126	abc transporter atp-binding protein
Srufu_RS23270	COG0765	amino acid transport
Srufu_RS23275	COG0765	amino acid transport
Srufu_RS23290	COG0154	amidase activity
Srufu_RS23310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Srufu_RS23380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Srufu_RS23395	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Srufu_RS23405	COG0745	RESPONSE REGULATOR receiver
Srufu_RS23415	COG3979	chitinase
Srufu_RS23425	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Srufu_RS23430	COG4977	sequence-specific DNA binding
Srufu_RS23435	COG0589	response to stress
Srufu_RS23440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Srufu_RS23455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Srufu_RS23465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Srufu_RS23485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Srufu_RS23490	COG1309	transcriptional regulator
Srufu_RS23500	COG1946	Acyl-CoA thioesterase
Srufu_RS23575	COG1335	isochorismatase
Srufu_RS23615	COG0028	Belongs to the TPP enzyme family
Srufu_RS23630	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Srufu_RS23650	COG1472	Belongs to the glycosyl hydrolase 3 family
Srufu_RS23665	COG0673	inositol 2-dehydrogenase activity
Srufu_RS23680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Srufu_RS23695	COG2608	mercury ion transmembrane transporter activity
Srufu_RS23700	COG0586	Pfam SNARE associated Golgi protein
Srufu_RS23705	COG0673	inositol 2-dehydrogenase activity
Srufu_RS23720	COG3409	Peptidoglycan-binding domain 1 protein
Srufu_RS23730	COG0673	inositol 2-dehydrogenase activity
Srufu_RS23740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Srufu_RS23755	COG3962	Belongs to the TPP enzyme family
Srufu_RS23770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Srufu_RS23780	COG1131	(ABC) transporter
Srufu_RS23790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Srufu_RS23805	COG0596	Alpha beta hydrolase
Srufu_RS23840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS23865	COG1113	amino acid transport
Srufu_RS23885	COG5285	phytanoyl-CoA dioxygenase
Srufu_RS23895	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Srufu_RS23920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS23930	COG0583	DNA-binding transcription factor activity
Srufu_RS23935	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Srufu_RS23945	COG1278	Cold shock
Srufu_RS23950	COG0513	Belongs to the DEAD box helicase family
Srufu_RS24010	COG1115	amino acid carrier protein
Srufu_RS24025	COG1585	Membrane protein implicated in regulation of membrane protease activity
Srufu_RS24080	COG1136	(ABC) transporter
Srufu_RS24090	COG2346	COG2346, Truncated hemoglobins
Srufu_RS24120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Srufu_RS24130	COG2186	Transcriptional regulator
Srufu_RS24140	COG1486	melibiose metabolic process
Srufu_RS24145	COG1846	Transcriptional regulator
Srufu_RS24145	COG1940	carbohydrate kinase activity
Srufu_RS24150	COG0668	transmembrane transport
Srufu_RS24185	COG0583	DNA-binding transcription factor activity
Srufu_RS24190	COG4266	Belongs to the allantoicase family
Srufu_RS24230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Srufu_RS24235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Srufu_RS24240	COG1113	amino acid transport
Srufu_RS24245	COG1113	amino acid transport
Srufu_RS24255	COG1113	amino acid transport
Srufu_RS24260	COG0698	ribose 5-phosphate isomerase
Srufu_RS24280	COG3594	Acyltransferase
Srufu_RS24305	COG0544	peptidyl-prolyl cis-trans isomerase activity
Srufu_RS24310	COG0740	serine-type endopeptidase activity
Srufu_RS24315	COG0740	serine-type endopeptidase activity
Srufu_RS24320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Srufu_RS24330	COG0525	valine-tRNA ligase activity
Srufu_RS24335	COG0768	penicillin binding
Srufu_RS24340	COG0285	dihydrofolate synthase activity
Srufu_RS24350	COG0105	UTP biosynthetic process
Srufu_RS24355	COG1077	Cell shape determining protein MreB Mrl
Srufu_RS24370	COG0768	penicillin binding
Srufu_RS24375	COG0772	Belongs to the SEDS family
Srufu_RS24415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Srufu_RS24420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Srufu_RS24425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Srufu_RS24435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Srufu_RS24445	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Srufu_RS24460	COG0501	Belongs to the peptidase M48B family
Srufu_RS24475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Srufu_RS24485	COG0799	negative regulation of ribosome biogenesis
Srufu_RS24490	COG0588	phosphoglycerate mutase activity
Srufu_RS24525	COG0495	leucyl-tRNA aminoacylation
Srufu_RS24535	COG1307	EDD domain protein, DegV family
Srufu_RS24540	COG1555	photosystem II stabilization
Srufu_RS24550	COG1234	tRNA 3'-trailer cleavage
Srufu_RS24555	COG1959	2 iron, 2 sulfur cluster binding
Srufu_RS24560	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Srufu_RS24580	COG0268	Binds directly to 16S ribosomal RNA
Srufu_RS24585	COG0481	GTPase activity
Srufu_RS24625	COG0484	heat shock protein binding
Srufu_RS24650	COG0537	adenosine 5'-monophosphoramidase activity
Srufu_RS24655	COG1234	tRNA 3'-trailer cleavage
Srufu_RS24665	COG4948	Mandelate Racemase Muconate Lactonizing
Srufu_RS24695	COG1486	melibiose metabolic process
Srufu_RS24700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Srufu_RS24710	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Srufu_RS24735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Srufu_RS24740	COG2211	Major facilitator Superfamily
Srufu_RS24760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Srufu_RS24765	COG2755	lipolytic protein G-D-S-L family
Srufu_RS24820	COG1381	Involved in DNA repair and RecF pathway recombination
Srufu_RS24825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Srufu_RS24835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Srufu_RS24840	COG1121	(ABC) transporter
Srufu_RS24865	COG2197	response regulator
Srufu_RS24890	COG1309	transcriptional regulator
Srufu_RS24895	COG0667	Aldo Keto reductase
Srufu_RS24900	COG0477	Major facilitator Superfamily
Srufu_RS24940	COG0477	Major facilitator Superfamily
Srufu_RS24945	COG0519	Catalyzes the synthesis of GMP from XMP
Srufu_RS24950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Srufu_RS24950	COG0574	Belongs to the PEP-utilizing enzyme family
Srufu_RS24965	COG2175	clavaminate synthase activity
Srufu_RS24975	COG0395	ABC-type sugar transport system, permease component
Srufu_RS24980	COG1175	transmembrane transport
Srufu_RS25035	COG0640	Transcriptional regulator
Srufu_RS25050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Srufu_RS25050	COG2146	nitrite reductase [NAD(P)H] activity
Srufu_RS25105	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Srufu_RS25145	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Srufu_RS25160	COG0358	DNA primase activity
Srufu_RS25165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Srufu_RS25170	COG1070	Carbohydrate kinase
Srufu_RS25215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Srufu_RS25220	COG0588	phosphoglycerate mutase activity
Srufu_RS25225	COG1077	Cell shape determining protein MreB Mrl
Srufu_RS25265	COG0500	methyltransferase
Srufu_RS25295	COG0477	Major facilitator Superfamily
Srufu_RS25305	COG2130	NADP-dependent
Srufu_RS25310	COG1764	response to oxidative stress
Srufu_RS25315	COG1609	Transcriptional regulator
Srufu_RS25320	COG1129	ABC transporter
Srufu_RS25325	COG1172	Belongs to the binding-protein-dependent transport system permease family
Srufu_RS25390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS25395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS25400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Srufu_RS25425	COG0789	Transcriptional regulator
Srufu_RS25430	COG0667	Aldo Keto reductase
Srufu_RS25440	COG2197	response regulator
Srufu_RS25445	COG4585	Histidine kinase
Srufu_RS25460	COG1309	transcriptional regulator
Srufu_RS25465	COG0477	Major facilitator Superfamily
Srufu_RS25475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Srufu_RS25520	COG1358	cellular component organization or biogenesis
Srufu_RS25530	COG0586	Pfam SNARE associated Golgi protein
Srufu_RS25535	COG4585	Histidine kinase
Srufu_RS25560	COG0800	Aldolase
Srufu_RS25565	COG4948	Mandelate Racemase Muconate Lactonizing
Srufu_RS25570	COG2186	Transcriptional regulator
Srufu_RS25595	COG0583	DNA-binding transcription factor activity
Srufu_RS25615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Srufu_RS25625	COG2259	Doxx family
Srufu_RS25635	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Srufu_RS25640	COG0596	Alpha beta hydrolase
Srufu_RS25655	COG1072	(Pantothenic acid kinase))
Srufu_RS25660	COG0662	Cupin 2, conserved barrel domain protein
Srufu_RS25665	COG1309	transcriptional regulator
Srufu_RS25715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Srufu_RS25755	COG0477	Major facilitator Superfamily
Srufu_RS25770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Srufu_RS25795	COG2124	cytochrome p450
Srufu_RS25800	COG0183	Belongs to the thiolase family
Srufu_RS25815	COG3845	ABC transporter
Srufu_RS25835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Srufu_RS25850	COG1309	transcriptional regulator
Srufu_RS25875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Srufu_RS25885	COG0860	N-Acetylmuramoyl-L-alanine amidase
Srufu_RS25895	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS25900	COG0183	Belongs to the thiolase family
Srufu_RS25910	COG2197	response regulator
Srufu_RS25915	COG4585	Histidine kinase
Srufu_RS25925	COG1131	(ABC) transporter
Srufu_RS25930	COG2030	dehydratase
Srufu_RS25975	COG3022	response to hydroperoxide
Srufu_RS25980	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Srufu_RS26000	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS26030	COG3629	intracellular signal transduction
Srufu_RS26055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS26060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS26065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS26070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Srufu_RS26085	COG2345	Transcriptional regulator
Srufu_RS26095	COG4221	oxidoreductase activity
Srufu_RS26095	COG0604	alcohol dehydrogenase
Srufu_RS26095	COG3321	synthase
Srufu_RS26095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS26110	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS26120	COG3540	Alkaline phosphatase
Srufu_RS26125	COG2814	Major facilitator Superfamily
Srufu_RS26130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Srufu_RS26140	COG1834	amidinotransferase
Srufu_RS26165	COG0672	)-iron permease
Srufu_RS26170	COG2837	iron assimilation
Srufu_RS26185	COG5398	heme oxygenase
Srufu_RS26215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Srufu_RS26220	COG2186	Transcriptional regulator
Srufu_RS26240	COG1175	transmembrane transport
Srufu_RS26245	COG0395	ABC-type sugar transport system, permease component
Srufu_RS26260	COG1994	Peptidase M50
Srufu_RS26280	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Srufu_RS26285	COG0477	Major facilitator Superfamily
Srufu_RS26290	COG1309	transcriptional regulator
Srufu_RS26300	COG2814	Major facilitator Superfamily
Srufu_RS26305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Srufu_RS26305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Srufu_RS26310	COG2132	Multicopper oxidase
Srufu_RS26315	COG0174	glutamine synthetase
Srufu_RS26330	COG1609	Transcriptional regulator
Srufu_RS26335	COG0366	Alpha amylase catalytic
Srufu_RS26340	COG2182	Extracellular solute-binding protein
Srufu_RS26345	COG1175	transmembrane transport
Srufu_RS26350	COG0395	ABC-type sugar transport system, permease component
Srufu_RS26355	COG0366	Alpha amylase catalytic
Srufu_RS26410	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
Srufu_RS26445	COG1309	transcriptional regulator
Srufu_RS26470	COG2197	response regulator
Srufu_RS26495	COG0745	RESPONSE REGULATOR receiver
Srufu_RS26525	COG1695	Transcriptional regulator
Srufu_RS26530	COG1902	pentaerythritol trinitrate reductase activity
Srufu_RS26530	COG0446	pyridine nucleotide-disulphide oxidoreductase
Srufu_RS26600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Srufu_RS26605	COG0321	lipoyl(octanoyl) transferase activity
Srufu_RS26620	COG1090	epimerase
Srufu_RS26650	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Srufu_RS26665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Srufu_RS26670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Srufu_RS26690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Srufu_RS26690	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Srufu_RS26695	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Srufu_RS26730	COG4585	Histidine kinase
Srufu_RS26740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Srufu_RS26745	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Srufu_RS26755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Srufu_RS26775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Srufu_RS26785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Srufu_RS26790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Srufu_RS26800	COG1376	ErfK ybiS ycfS ynhG family protein
Srufu_RS26810	COG1845	cytochrome c oxidase, subunit III
Srufu_RS26815	COG2010	Cytochrome c
Srufu_RS26820	COG0723	plastoquinol--plastocyanin reductase activity
Srufu_RS26825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Srufu_RS26830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Srufu_RS26875	COG0438	transferase activity, transferring glycosyl groups
Srufu_RS26895	COG0003	Pfam Anion-transporting ATPase
Srufu_RS26905	COG1940	carbohydrate kinase activity
Srufu_RS26935	COG2197	response regulator
Srufu_RS26940	COG0205	6-phosphofructokinase activity
Srufu_RS26945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Srufu_RS26955	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Srufu_RS26965	COG2193	ferroxidase activity
Srufu_RS26970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Srufu_RS26980	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Srufu_RS26990	COG2022	thiamine diphosphate biosynthetic process
Srufu_RS27015	COG0352	thiamine-phosphate diphosphorylase activity
Srufu_RS27030	COG1233	COG1233 Phytoene dehydrogenase and related
Srufu_RS27040	COG1309	transcriptional regulator
Srufu_RS27060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Srufu_RS27080	COG0714	Associated with various cellular activities
Srufu_RS27090	COG0275	rRNA processing
Srufu_RS27105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Srufu_RS27110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Srufu_RS27115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Srufu_RS27130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Srufu_RS27135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Srufu_RS27155	COG1799	cell septum assembly
Srufu_RS27165	COG3599	regulation of cell shape
Srufu_RS27170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Srufu_RS27180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Srufu_RS27245	COG1432	Conserved Protein
Srufu_RS27265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Srufu_RS27280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Srufu_RS27285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Srufu_RS27290	COG0131	Imidazoleglycerol-phosphate dehydratase
Srufu_RS27300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Srufu_RS27305	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Srufu_RS27335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Srufu_RS27340	COG1053	succinate dehydrogenase
Srufu_RS27350	COG0583	DNA-binding transcription factor activity
Srufu_RS27365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Srufu_RS27370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Srufu_RS27390	COG0134	indole-3-glycerol-phosphate synthase activity
Srufu_RS27395	COG0133	tryptophan synthase activity
Srufu_RS27400	COG0159	tryptophan synthase activity
Srufu_RS27410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Srufu_RS27420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Srufu_RS27450	COG0070	glutamate synthase
Srufu_RS27450	COG0067	glutamate synthase
Srufu_RS27450	COG0069	glutamate synthase activity
Srufu_RS27460	COG0640	Transcriptional regulator
Srufu_RS27465	COG3467	pyridoxamine 5'-phosphate
Srufu_RS27475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Srufu_RS27505	COG0366	Alpha amylase catalytic
Srufu_RS27505	COG1470	cell adhesion involved in biofilm formation
Srufu_RS27590	COG2050	protein possibly involved in aromatic compounds catabolism
Srufu_RS27630	COG1643	Atp-dependent helicase
Srufu_RS27635	COG2226	methyltransferase
Srufu_RS27650	COG0237	dephospho-CoA kinase activity
Srufu_RS27675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Srufu_RS27725	COG0584	glycerophosphoryl diester phosphodiesterase
Srufu_RS27730	COG0556	nucleotide-excision repair
Srufu_RS27770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Srufu_RS27780	COG1609	Transcriptional regulator
Srufu_RS27805	COG0322	excinuclease ABC activity
Srufu_RS27810	COG1660	Displays ATPase and GTPase activities
Srufu_RS27820	COG1481	regulation of sporulation
Srufu_RS27830	COG0126	phosphoglycerate kinase activity
Srufu_RS27835	COG0149	triose-phosphate isomerase activity
Srufu_RS27840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Srufu_RS27855	COG0166	Belongs to the GPI family
Srufu_RS27875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Srufu_RS27885	COG0109	protoheme IX farnesyltransferase activity
Srufu_RS27910	COG1131	(ABC) transporter
Srufu_RS27935	COG0396	ATPase activity
Srufu_RS27940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Srufu_RS27945	COG0822	iron-sulfur transferase activity
Srufu_RS27955	COG2076	Multidrug Resistance protein
Srufu_RS27960	COG3226	Transcriptional regulator
Srufu_RS27965	COG2171	N-acyltransferase activity
Srufu_RS27975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Srufu_RS28010	COG2261	transglycosylase associated protein
Srufu_RS28015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Srufu_RS28035	COG1414	Transcriptional regulator
Srufu_RS28065	COG1902	pentaerythritol trinitrate reductase activity
Srufu_RS28075	COG1917	Cupin 2, conserved barrel domain protein
Srufu_RS28080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Srufu_RS28105	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
Srufu_RS28115	COG1797	cobyrinic acid a,c-diamide synthase activity
Srufu_RS28130	COG1492	cobalamin metabolic process
Srufu_RS28150	COG1653	transport
Srufu_RS28165	COG0235	Class ii aldolase
Srufu_RS28180	COG0488	(ABC) transporter
Srufu_RS28230	COG3387	PFAM Glycoside hydrolase 15-related
Srufu_RS28245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Srufu_RS28275	COG1819	glycosyl
Srufu_RS28310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Srufu_RS28315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Srufu_RS28335	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Srufu_RS28350	COG0640	Transcriptional regulator
Srufu_RS28355	COG0798	PFAM Bile acid sodium symporter
Srufu_RS28360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Srufu_RS28375	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Srufu_RS28380	COG2186	Transcriptional regulator
Srufu_RS28400	COG0560	Phosphoserine phosphatase
Srufu_RS28400	COG3830	Belongs to the UPF0237 family
Srufu_RS28415	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Srufu_RS28420	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS28425	COG4585	Histidine kinase
Srufu_RS28430	COG2197	response regulator
Srufu_RS28450	COG1119	ATPase activity
Srufu_RS28475	COG1881	PFAM PEBP family protein
Srufu_RS28520	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Srufu_RS28535	COG0647	UMP catabolic process
Srufu_RS28550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Srufu_RS28555	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Srufu_RS28560	COG1120	ATPase activity
Srufu_RS28580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Srufu_RS28590	COG0497	DNA recombination
Srufu_RS28600	COG4941	Belongs to the sigma-70 factor family
Srufu_RS28605	COG3795	YCII-related domain
Srufu_RS28635	COG3387	PFAM Glycoside hydrolase 15-related
Srufu_RS28640	COG0504	CTP synthase activity
Srufu_RS28645	COG0494	nUDIX hydrolase
Srufu_RS28655	COG0686	Belongs to the AlaDH PNT family
Srufu_RS28670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Srufu_RS28675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Srufu_RS28680	COG1187	pseudouridine synthase activity
Srufu_RS28700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Srufu_RS28710	COG1160	GTP binding
Srufu_RS28735	COG0438	transferase activity, transferring glycosyl groups
Srufu_RS28750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Srufu_RS28760	COG0671	phosphoesterase, PA-phosphatase related
Srufu_RS28770	COG0477	Major facilitator Superfamily
Srufu_RS28775	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS28780	COG1799	cell septum assembly
Srufu_RS28790	COG0330	HflC and HflK could
Srufu_RS28815	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS28825	COG0587	DNA-directed DNA polymerase activity
Srufu_RS28830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Srufu_RS28860	COG0531	amino acid
Srufu_RS28865	COG1522	sequence-specific DNA binding
Srufu_RS28885	COG0367	asparagine synthase
Srufu_RS28895	COG1725	Transcriptional regulator
Srufu_RS28900	COG1834	amidinotransferase
Srufu_RS28925	COG1309	transcriptional regulator
Srufu_RS28935	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Srufu_RS28995	COG0477	Major facilitator Superfamily
Srufu_RS28995	COG2814	Major facilitator Superfamily
Srufu_RS29000	COG2188	Transcriptional regulator
Srufu_RS29005	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Srufu_RS29010	COG1309	transcriptional regulator
Srufu_RS29015	COG2851	Citrate transporter
Srufu_RS29025	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Srufu_RS29070	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS29115	COG0477	Major facilitator Superfamily
Srufu_RS29120	COG3876	Protein conserved in bacteria
Srufu_RS29125	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS29130	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS29135	COG1309	transcriptional regulator
Srufu_RS29140	COG3963	phosphatidate phosphatase activity
Srufu_RS29170	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Srufu_RS29210	COG2205	protein histidine kinase activity
Srufu_RS29215	COG0745	RESPONSE REGULATOR receiver
Srufu_RS29225	COG2124	cytochrome p450
Srufu_RS29230	COG0488	(ABC) transporter
Srufu_RS29255	COG0564	pseudouridine synthase activity
Srufu_RS29280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Srufu_RS29310	COG0667	Aldo Keto reductase
Srufu_RS29315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Srufu_RS29325	COG0598	Magnesium transport protein CorA
Srufu_RS29345	COG0215	cysteine-tRNA ligase activity
Srufu_RS29355	COG4948	Mandelate Racemase Muconate Lactonizing
Srufu_RS29360	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS29370	COG1129	ABC transporter
Srufu_RS29390	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS29395	COG2186	Transcriptional regulator
Srufu_RS29405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Srufu_RS29410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Srufu_RS29415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Srufu_RS29420	COG1414	Transcriptional regulator
Srufu_RS29430	COG0546	phosphoglycolate phosphatase activity
Srufu_RS29435	COG4166	transmembrane transport
Srufu_RS29445	COG2197	response regulator
Srufu_RS29455	COG1994	Peptidase M50
Srufu_RS29455	COG0517	IMP dehydrogenase activity
Srufu_RS29475	COG1222	aaa ATPase
Srufu_RS29480	COG4122	O-methyltransferase activity
Srufu_RS29495	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Srufu_RS29500	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Srufu_RS29515	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Srufu_RS29520	COG0545	Peptidyl-prolyl cis-trans isomerase
Srufu_RS29550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Srufu_RS29555	COG0805	protein transport
Srufu_RS29595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Srufu_RS29630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Srufu_RS29635	COG0531	amino acid
Srufu_RS29640	COG2186	Transcriptional regulator
Srufu_RS29650	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS29685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Srufu_RS29695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Srufu_RS29700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Srufu_RS29705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Srufu_RS29710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Srufu_RS29720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Srufu_RS29725	COG0072	phenylalanine-tRNA ligase activity
Srufu_RS29725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Srufu_RS29740	COG1051	belongs to the nudix hydrolase family
Srufu_RS29775	COG1649	PFAM Uncharacterised BCR, COG1649
Srufu_RS29785	COG0697	spore germination
Srufu_RS29825	COG4106	trans-aconitate 2-methyltransferase activity
Srufu_RS29840	COG0596	Alpha beta hydrolase
Srufu_RS29845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Srufu_RS29850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Srufu_RS29855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Srufu_RS29860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Srufu_RS29865	COG1438	arginine binding
Srufu_RS29870	COG0668	transmembrane transport
Srufu_RS29875	COG1720	tRNA m6t6A37 methyltransferase activity
Srufu_RS29890	COG0137	argininosuccinate synthase activity
Srufu_RS29905	COG0477	Major facilitator Superfamily
Srufu_RS29915	COG0204	Acyl-transferase
Srufu_RS29915	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS29945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Srufu_RS29950	COG2011	ABC-type metal ion transport system permease component
Srufu_RS29970	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Srufu_RS29975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Srufu_RS29975	COG1648	precorrin-2 dehydrogenase activity
Srufu_RS29985	COG0515	serine threonine protein kinase
Srufu_RS29985	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Srufu_RS30030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Srufu_RS30090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Srufu_RS30105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Srufu_RS30140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Srufu_RS30145	COG1560	Kdo2-lipid A biosynthetic process
Srufu_RS30150	COG0438	transferase activity, transferring glycosyl groups
Srufu_RS30160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Srufu_RS30165	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Srufu_RS30170	COG0217	transcriptional regulatory protein
Srufu_RS30175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Srufu_RS30180	COG0632	four-way junction helicase activity
Srufu_RS30185	COG2255	four-way junction helicase activity
Srufu_RS30195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Srufu_RS30200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Srufu_RS30205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Srufu_RS30210	COG1196	nuclear chromosome segregation
Srufu_RS30215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Srufu_RS30225	COG0124	histidyl-tRNA synthetase
Srufu_RS30245	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Srufu_RS30265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Srufu_RS30270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Srufu_RS30280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Srufu_RS30285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Srufu_RS30290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Srufu_RS30295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Srufu_RS30300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Srufu_RS30310	COG0006	proline dipeptidase activity
Srufu_RS30315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Srufu_RS30320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Srufu_RS30330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Srufu_RS30335	COG0540	Belongs to the ATCase OTCase family
Srufu_RS30340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Srufu_RS30350	COG0505	Belongs to the CarA family
Srufu_RS30355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Srufu_RS30360	COG0167	dihydroorotate dehydrogenase activity
Srufu_RS30365	COG0284	orotidine-5'-phosphate decarboxylase activity
Srufu_RS30390	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Srufu_RS30405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Srufu_RS30415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Srufu_RS30440	COG0531	amino acid
Srufu_RS30450	COG0477	Major facilitator Superfamily
Srufu_RS30460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Srufu_RS30470	COG0456	acetyltransferase
Srufu_RS30480	COG2233	PERMEase
Srufu_RS30495	COG1335	isochorismatase
Srufu_RS30505	COG2223	nitrite transmembrane transporter activity
Srufu_RS30510	COG1940	carbohydrate kinase activity
Srufu_RS30510	COG1846	Transcriptional regulator
Srufu_RS30515	COG1090	epimerase
Srufu_RS30530	COG3201	nicotinamide mononucleotide transporter
Srufu_RS30535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Srufu_RS30535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Srufu_RS30540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Srufu_RS30545	COG0140	phosphoribosyl-ATP diphosphatase activity
Srufu_RS30550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Srufu_RS30625	COG0667	Aldo Keto reductase
Srufu_RS30665	COG0583	DNA-binding transcription factor activity
Srufu_RS30755	COG3903	Transcriptional regulator
Srufu_RS30755	COG3629	intracellular signal transduction
Srufu_RS30770	COG2197	response regulator
Srufu_RS30820	COG0671	phosphoesterase, PA-phosphatase related
Srufu_RS30850	COG0765	amino acid transport
Srufu_RS30860	COG0584	glycerophosphoryl diester phosphodiesterase
Srufu_RS30905	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Srufu_RS30910	COG2318	DinB family
Srufu_RS30940	COG3345	alpha-galactosidase
Srufu_RS30955	COG0395	ABC-type sugar transport system, permease component
Srufu_RS30975	COG0445	tRNA wobble uridine modification
Srufu_RS30980	COG4585	Histidine kinase
Srufu_RS30985	COG2197	response regulator
Srufu_RS30995	COG2223	nitrite transmembrane transporter activity
Srufu_RS31000	COG1940	carbohydrate kinase activity
Srufu_RS31065	COG1349	DNA-binding transcription factor activity
Srufu_RS31110	COG1215	transferase activity, transferring glycosyl groups
Srufu_RS31115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Srufu_RS31135	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS31235	COG3415	Transposase
Srufu_RS31235	COG2801	Transposase and inactivated derivatives
Srufu_RS31250	COG0647	UMP catabolic process
Srufu_RS31255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Srufu_RS31270	COG0590	tRNA wobble adenosine to inosine editing
Srufu_RS31275	COG3224	Antibiotic biosynthesis monooxygenase
Srufu_RS31280	COG0277	FAD linked oxidase domain protein
Srufu_RS31285	COG1793	dna ligase
Srufu_RS31300	COG0789	Transcriptional regulator
Srufu_RS31315	COG1063	alcohol dehydrogenase
Srufu_RS31320	COG0395	ABC-type sugar transport system, permease component
Srufu_RS31365	COG1461	Dihydroxyacetone kinase
Srufu_RS31370	COG2376	Dihydroxyacetone kinase
Srufu_RS31455	COG0783	Belongs to the Dps family
Srufu_RS31460	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS31490	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Srufu_RS31525	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Srufu_RS31560	COG0243	molybdopterin cofactor binding
Srufu_RS31575	COG4264	IucA IucC family
Srufu_RS31580	COG2814	Major facilitator Superfamily
Srufu_RS31590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Srufu_RS31595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Srufu_RS31600	COG1120	ATPase activity
Srufu_RS31605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Srufu_RS31610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Srufu_RS31640	COG0515	serine threonine protein kinase
Srufu_RS31655	COG2070	2-Nitropropane dioxygenase
Srufu_RS31665	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS31685	COG1605	Chorismate mutase
Srufu_RS31780	COG0438	transferase activity, transferring glycosyl groups
Srufu_RS31800	COG0477	Major facilitator Superfamily
Srufu_RS31810	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Srufu_RS31815	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Srufu_RS31835	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Srufu_RS31860	COG1414	Transcriptional regulator
Srufu_RS31865	COG2146	nitrite reductase [NAD(P)H] activity
Srufu_RS31900	COG0596	Alpha beta hydrolase
Srufu_RS31915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Srufu_RS31920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Srufu_RS31945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Srufu_RS31955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Srufu_RS31985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Srufu_RS32005	COG1716	ATPase activity
Srufu_RS32025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Srufu_RS32035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Srufu_RS32035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Srufu_RS32110	COG0697	spore germination
Srufu_RS32115	COG0583	DNA-binding transcription factor activity
Srufu_RS32120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Srufu_RS32120	COG0825	malonyl-CoA metabolic process
Srufu_RS32125	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS32155	COG2986	histidine ammonia-lyase
Srufu_RS32180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS32185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS32190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Srufu_RS32205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Srufu_RS32220	COG3629	intracellular signal transduction
Srufu_RS32235	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS32250	COG0738	Major facilitator superfamily
Srufu_RS32285	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Srufu_RS32290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Srufu_RS32295	COG1280	lysine exporter protein (LysE YggA)
Srufu_RS32305	COG3548	integral membrane protein
Srufu_RS32345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Srufu_RS32350	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS32355	COG2197	response regulator
Srufu_RS32375	COG2197	response regulator
Srufu_RS32440	COG3321	synthase
Srufu_RS32440	COG0604	alcohol dehydrogenase
Srufu_RS32450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS32490	COG0154	amidase activity
Srufu_RS32495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Srufu_RS32535	COG4585	Histidine kinase
Srufu_RS32540	COG2197	response regulator
Srufu_RS32545	COG2304	oxidoreductase activity
Srufu_RS32560	COG4221	oxidoreductase activity
Srufu_RS32570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Srufu_RS32605	COG1191	sigma factor activity
Srufu_RS32620	COG0154	amidase activity
Srufu_RS32625	COG0477	Major facilitator Superfamily
Srufu_RS32630	COG1012	belongs to the aldehyde dehydrogenase family
Srufu_RS32645	COG2267	carboxylic ester hydrolase activity
Srufu_RS32685	COG1846	Transcriptional regulator
Srufu_RS32715	COG2124	cytochrome p450
Srufu_RS32720	COG2124	cytochrome p450
Srufu_RS32740	COG2313	pseudouridylate synthase activity
Srufu_RS32745	COG3971	2-oxopent-4-enoate hydratase activity
Srufu_RS32750	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Srufu_RS32755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Srufu_RS32775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Srufu_RS32825	COG2801	Transposase and inactivated derivatives
Srufu_RS32825	COG3415	Transposase
Srufu_RS32975	COG4974	Belongs to the 'phage' integrase family
Srufu_RS33005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Srufu_RS33030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Srufu_RS33040	COG1132	(ABC) transporter
Srufu_RS33055	COG0386	Belongs to the glutathione peroxidase family
Srufu_RS33085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Srufu_RS33130	COG0640	Transcriptional regulator
Srufu_RS33155	COG0438	transferase activity, transferring glycosyl groups
Srufu_RS33180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Srufu_RS33210	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Srufu_RS33265	COG3585	molybdate ion transport
Srufu_RS33300	COG0477	Major facilitator Superfamily
Srufu_RS33325	COG0745	RESPONSE REGULATOR receiver
Srufu_RS33345	COG2318	DinB family
Srufu_RS33375	COG1063	alcohol dehydrogenase
Srufu_RS33380	COG0156	8-amino-7-oxononanoate synthase activity
Srufu_RS33385	COG0583	DNA-binding transcription factor activity
Srufu_RS33400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Srufu_RS33400	COG1796	DNA polymerase
Srufu_RS33420	COG2274	protein secretion by the type I secretion system
Srufu_RS33480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Srufu_RS33485	COG1120	ATPase activity
Srufu_RS33560	COG2423	ornithine cyclodeaminase activity
Srufu_RS33570	COG0626	cystathionine gamma-synthase activity
Srufu_RS33575	COG3135	benzoate transporter
Srufu_RS33580	COG1902	pentaerythritol trinitrate reductase activity
Srufu_RS33590	COG2268	Band 7 protein
Srufu_RS33610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Srufu_RS33645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Srufu_RS33660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Srufu_RS33680	COG1595	DNA-templated transcription, initiation
Srufu_RS33700	COG0247	lactate metabolic process
Srufu_RS33705	COG1139	Iron-sulfur cluster binding protein
Srufu_RS33710	COG1556	Lactate utilization protein
Srufu_RS33735	COG2186	Transcriptional regulator
Srufu_RS33745	COG4565	transcriptional regulatory protein
Srufu_RS33750	COG3290	protein histidine kinase activity
Srufu_RS33760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Srufu_RS33790	COG3591	Belongs to the peptidase S1B family
Srufu_RS33790	COG1864	DNA RNA non-specific endonuclease
Srufu_RS33810	COG0542	response to heat
Srufu_RS33835	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS33840	COG1960	acyl-CoA dehydrogenase activity
Srufu_RS33845	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS33850	COG0183	Belongs to the thiolase family
Srufu_RS33885	COG2814	Major facilitator Superfamily
Srufu_RS33895	COG1802	Transcriptional regulator
Srufu_RS33900	COG0006	proline dipeptidase activity
Srufu_RS33920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Srufu_RS33945	COG2326	polyphosphate kinase activity
Srufu_RS33965	COG4214	carbohydrate transport
Srufu_RS33975	COG4213	ABC transporter substrate-binding protein
Srufu_RS34030	COG1113	amino acid transport
Srufu_RS34055	COG1968	undecaprenyl-diphosphatase activity
Srufu_RS34080	COG0179	Fumarylacetoacetate (FAA) hydrolase
Srufu_RS34085	COG1414	Transcriptional regulator
Srufu_RS34090	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Srufu_RS34160	COG1132	(ABC) transporter
Srufu_RS34165	COG1132	(ABC) transporter
Srufu_RS34170	COG2197	response regulator
Srufu_RS34230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Srufu_RS34235	COG0443	Heat shock 70 kDa protein
Srufu_RS34240	COG3424	synthase
Srufu_RS34250	COG4221	oxidoreductase activity
Srufu_RS34270	COG0513	Belongs to the DEAD box helicase family
Srufu_RS34275	COG1278	Cold shock
Srufu_RS34280	COG0516	GMP reductase activity
Srufu_RS34280	COG0517	IMP dehydrogenase activity
Srufu_RS34300	COG0516	GMP reductase activity
Srufu_RS34300	COG0517	IMP dehydrogenase activity
Srufu_RS34335	COG2814	Major facilitator Superfamily
Srufu_RS34350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Srufu_RS34355	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS34370	COG1121	(ABC) transporter
Srufu_RS34385	COG0384	phenazine biosynthesis protein PhzF
Srufu_RS34420	COG4191	Histidine kinase
Srufu_RS34450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Srufu_RS34550	COG1172	Belongs to the binding-protein-dependent transport system permease family
Srufu_RS34555	COG1129	ABC transporter
Srufu_RS34570	COG0277	FAD linked oxidase domain protein
Srufu_RS34615	COG1573	uracil-dna glycosylase
Srufu_RS34660	COG0477	Major facilitator Superfamily
Srufu_RS34665	COG1051	belongs to the nudix hydrolase family
Srufu_RS34740	COG2318	DinB family
Srufu_RS34745	COG3655	Transcriptional regulator
Srufu_RS34765	COG1132	(ABC) transporter
Srufu_RS34770	COG0583	DNA-binding transcription factor activity
Srufu_RS34845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Srufu_RS34855	COG3186	Phenylalanine-4-hydroxylase
Srufu_RS34865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Srufu_RS34870	COG1509	lysine 2,3-aminomutase activity
Srufu_RS34880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Srufu_RS34885	COG0473	3-isopropylmalate dehydrogenase activity
Srufu_RS34890	COG0010	Belongs to the arginase family
Srufu_RS34895	COG0066	3-isopropylmalate dehydratase activity
Srufu_RS34900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Srufu_RS34905	COG0778	Nitroreductase
Srufu_RS34910	COG0542	response to heat
Srufu_RS34915	COG0475	glutathione-regulated potassium exporter activity
Srufu_RS34935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Srufu_RS34950	COG1366	Belongs to the anti-sigma-factor antagonist family
Srufu_RS34955	COG1366	Belongs to the anti-sigma-factor antagonist family
Srufu_RS34960	COG2172	sigma factor antagonist activity
Srufu_RS34970	COG2208	phosphoserine phosphatase activity
Srufu_RS35015	COG1819	glycosyl
Srufu_RS35140	COG3842	ATPase activity
Srufu_RS35260	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS35265	COG2124	cytochrome p450
Srufu_RS35315	COG0745	RESPONSE REGULATOR receiver
Srufu_RS35325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Srufu_RS35335	COG1509	lysine 2,3-aminomutase activity
Srufu_RS35340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Srufu_RS35360	COG2226	methyltransferase
Srufu_RS35395	COG0626	cystathionine gamma-synthase activity
Srufu_RS35405	COG2897	thiosulfate sulfurtransferase activity
Srufu_RS35425	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS35430	COG0513	Belongs to the DEAD box helicase family
Srufu_RS35465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Srufu_RS35500	COG0069	glutamate synthase activity
Srufu_RS35565	COG0829	nickel cation binding
Srufu_RS35570	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Srufu_RS35585	COG0832	Belongs to the urease beta subunit family
Srufu_RS35585	COG0831	urea catabolic process
Srufu_RS35600	COG1280	lysine exporter protein (LysE YggA)
Srufu_RS35615	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Srufu_RS35625	COG1733	regulation of RNA biosynthetic process
Srufu_RS35675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Srufu_RS35740	COG0300	oxidoreductase activity
Srufu_RS35750	COG4948	Mandelate Racemase Muconate Lactonizing
Srufu_RS35755	COG0028	Belongs to the TPP enzyme family
Srufu_RS35760	COG0277	FAD linked oxidase domain protein
Srufu_RS35760	COG0247	lactate metabolic process
Srufu_RS35765	COG2890	protein-(glutamine-N5) methyltransferase activity
Srufu_RS35790	COG1028	Short-chain dehydrogenase reductase Sdr
Srufu_RS35840	COG2046	Belongs to the sulfate adenylyltransferase family
Srufu_RS35840	COG0529	Catalyzes the synthesis of activated sulfate
Srufu_RS35860	COG0659	secondary active sulfate transmembrane transporter activity
Srufu_RS35865	COG0789	Transcriptional regulator
Srufu_RS35895	COG1595	DNA-templated transcription, initiation
Srufu_RS35915	COG1595	DNA-templated transcription, initiation
Srufu_RS35925	COG1131	(ABC) transporter
Srufu_RS35965	COG1819	glycosyl
Srufu_RS35985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Srufu_RS36035	COG1794	racemase activity, acting on amino acids and derivatives
Srufu_RS36050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Srufu_RS36080	COG0181	hydroxymethylbilane synthase activity
Srufu_RS36115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Srufu_RS36150	COG3387	PFAM Glycoside hydrolase 15-related
Srufu_RS36170	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Srufu_RS36250	COG0655	NAD(P)H dehydrogenase (quinone) activity
Srufu_RS36285	COG0402	S-adenosylhomocysteine deaminase activity
Srufu_RS36325	COG1113	amino acid transport
Srufu_RS36345	COG0300	oxidoreductase activity
Srufu_RS36365	COG1271	oxidase subunit
Srufu_RS36405	COG2226	methyltransferase
Srufu_RS36410	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Srufu_RS36435	COG2814	Major facilitator Superfamily
Srufu_RS36440	COG1063	alcohol dehydrogenase
Srufu_RS36445	COG1349	DNA-binding transcription factor activity
Srufu_RS36460	COG0395	ABC-type sugar transport system, permease component
Srufu_RS36470	COG1653	transport
Srufu_RS36475	COG0366	Alpha amylase catalytic
Srufu_RS36480	COG1653	transport
Srufu_RS36490	COG0577	efflux transmembrane transporter activity
Srufu_RS36490	COG1136	(ABC) transporter
Srufu_RS36555	COG2340	Cysteine-rich secretory protein family
Srufu_RS36590	COG3647	Membrane
Srufu_RS36635	COG0009	L-threonylcarbamoyladenylate synthase
Srufu_RS36695	COG0601	transmembrane transport
Srufu_RS36700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Srufu_RS36705	COG4172	Belongs to the ABC transporter superfamily
Srufu_RS36725	COG4941	Belongs to the sigma-70 factor family
Srufu_RS36740	COG0529	Catalyzes the synthesis of activated sulfate
Srufu_RS36760	COG2364	Membrane
Srufu_RS36765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Srufu_RS36770	COG5504	Zn-dependent protease
Srufu_RS36785	COG0454	-acetyltransferase
Srufu_RS36815	COG3153	acetyltransferase
Srufu_RS36840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Srufu_RS36855	COG3963	phosphatidate phosphatase activity
Srufu_RS36885	COG0318	PFAM AMP-dependent synthetase and ligase
Srufu_RS36925	COG2801	Transposase and inactivated derivatives
Srufu_RS36925	COG3415	Transposase
Srufu_RS37025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Srufu_RS37385	COG1335	isochorismatase
Srufu_RS37390	COG3634	alkyl hydroperoxide reductase activity
Srufu_RS37410	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Srufu_RS37485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Srufu_RS37530	COG2197	response regulator