locus-tag	class	description
SLCG_RS00020	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS00020	COG1024	Enoyl-CoA hydratase
SLCG_RS00080	COG1309	transcriptional regulator
SLCG_RS00105	COG1309	transcriptional regulator
SLCG_RS00115	COG1609	Transcriptional regulator
SLCG_RS00165	COG3321	synthase
SLCG_RS00165	COG0604	alcohol dehydrogenase
SLCG_RS00170	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS00170	COG1024	Enoyl-CoA hydratase
SLCG_RS00195	COG1309	transcriptional regulator
SLCG_RS00200	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS00210	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS00220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS00245	COG1024	Enoyl-CoA hydratase
SLCG_RS00245	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS00255	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS00305	COG1063	alcohol dehydrogenase
SLCG_RS00315	COG1850	ribulose-bisphosphate carboxylase activity
SLCG_RS00445	COG0326	Molecular chaperone. Has ATPase activity
SLCG_RS00495	COG2814	Major facilitator Superfamily
SLCG_RS00500	COG0513	Belongs to the DEAD box helicase family
SLCG_RS00510	COG3328	transposase activity
SLCG_RS00530	COG1902	pentaerythritol trinitrate reductase activity
SLCG_RS00535	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS00545	COG1309	transcriptional regulator
SLCG_RS00550	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SLCG_RS00560	COG2801	Transposase and inactivated derivatives
SLCG_RS00570	COG1082	Xylose isomerase domain protein TIM barrel
SLCG_RS00575	COG0673	inositol 2-dehydrogenase activity
SLCG_RS00590	COG1609	Transcriptional regulator
SLCG_RS00645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS00650	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLCG_RS00650	COG0515	serine threonine protein kinase
SLCG_RS00665	COG0702	epimerase
SLCG_RS00765	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SLCG_RS00765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLCG_RS00850	COG0583	DNA-binding transcription factor activity
SLCG_RS00885	COG2226	methyltransferase
SLCG_RS00925	COG0456	acetyltransferase
SLCG_RS01045	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLCG_RS01105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLCG_RS01150	COG1595	DNA-templated transcription, initiation
SLCG_RS01160	COG1252	NADH dehydrogenase
SLCG_RS01165	COG1595	DNA-templated transcription, initiation
SLCG_RS01170	COG0494	nUDIX hydrolase
SLCG_RS01200	COG1309	transcriptional regulator
SLCG_RS01205	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS01235	COG0395	ABC-type sugar transport system, permease component
SLCG_RS01255	COG0577	efflux transmembrane transporter activity
SLCG_RS01255	COG1136	(ABC) transporter
SLCG_RS01260	COG1136	(ABC) transporter
SLCG_RS01275	COG0745	RESPONSE REGULATOR receiver
SLCG_RS01280	COG2205	protein histidine kinase activity
SLCG_RS01290	COG1733	regulation of RNA biosynthetic process
SLCG_RS01305	COG1120	ATPase activity
SLCG_RS01310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS01355	COG2226	methyltransferase
SLCG_RS01405	COG1733	regulation of RNA biosynthetic process
SLCG_RS01455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLCG_RS01465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLCG_RS01485	COG2226	methyltransferase
SLCG_RS01490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SLCG_RS01520	COG0746	molybdenum cofactor guanylyltransferase activity
SLCG_RS01525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SLCG_RS01530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLCG_RS01560	COG0384	phenazine biosynthesis protein PhzF
SLCG_RS01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS01575	COG0488	(ABC) transporter
SLCG_RS01600	COG4585	Histidine kinase
SLCG_RS01605	COG2197	response regulator
SLCG_RS01610	COG1695	Transcriptional regulator
SLCG_RS01645	COG1595	DNA-templated transcription, initiation
SLCG_RS01660	COG4585	Histidine kinase
SLCG_RS01665	COG2409	Drug exporters of the RND superfamily
SLCG_RS01680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SLCG_RS01680	COG0116	Belongs to the methyltransferase superfamily
SLCG_RS01695	COG0346	lactoylglutathione lyase activity
SLCG_RS01720	COG3903	Transcriptional regulator
SLCG_RS01720	COG3629	intracellular signal transduction
SLCG_RS01725	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS01760	COG1414	Transcriptional regulator
SLCG_RS01770	COG0765	amino acid transport
SLCG_RS01775	COG0765	amino acid transport
SLCG_RS01780	COG1126	abc transporter atp-binding protein
SLCG_RS01785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLCG_RS01810	COG3903	Transcriptional regulator
SLCG_RS01810	COG3629	intracellular signal transduction
SLCG_RS01820	COG1733	regulation of RNA biosynthetic process
SLCG_RS01825	COG0747	negative chemotaxis
SLCG_RS01840	COG0444	Belongs to the ABC transporter superfamily
SLCG_RS01845	COG4608	Belongs to the ABC transporter superfamily
SLCG_RS01865	COG1252	NADH dehydrogenase
SLCG_RS01875	COG0823	Involved in the tonB-independent uptake of proteins
SLCG_RS01875	COG1506	peptidase
SLCG_RS01950	COG2353	YceI-like domain
SLCG_RS01955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLCG_RS01975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SLCG_RS01985	COG1136	(ABC) transporter
SLCG_RS01985	COG0577	efflux transmembrane transporter activity
SLCG_RS01995	COG2197	response regulator
SLCG_RS02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS02020	COG1120	ATPase activity
SLCG_RS02065	COG3629	intracellular signal transduction
SLCG_RS02065	COG3903	Transcriptional regulator
SLCG_RS02070	COG0596	Alpha beta hydrolase
SLCG_RS02090	COG0789	Transcriptional regulator
SLCG_RS02095	COG0009	L-threonylcarbamoyladenylate synthase
SLCG_RS02105	COG3300	MHYT domain
SLCG_RS02105	COG5001	Diguanylate cyclase
SLCG_RS02140	COG1621	beta-fructofuranosidase activity
SLCG_RS02150	COG1175	transmembrane transport
SLCG_RS02155	COG0395	ABC-type sugar transport system, permease component
SLCG_RS02165	COG1609	Transcriptional regulator
SLCG_RS02170	COG0656	L-ascorbic acid biosynthetic process
SLCG_RS02190	COG1846	Transcriptional regulator
SLCG_RS02210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SLCG_RS02210	COG0512	Glutamine amidotransferase of anthranilate synthase
SLCG_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS02240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLCG_RS02245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLCG_RS02255	COG2030	dehydratase
SLCG_RS02265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLCG_RS02270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLCG_RS02295	COG2207	Transcriptional regulator
SLCG_RS02325	COG0745	RESPONSE REGULATOR receiver
SLCG_RS02340	COG2197	response regulator
SLCG_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS02355	COG1793	dna ligase
SLCG_RS02380	COG0181	hydroxymethylbilane synthase activity
SLCG_RS02390	COG0842	Transport permease protein
SLCG_RS02430	COG0366	Alpha amylase catalytic
SLCG_RS02440	COG3281	Trehalose synthase
SLCG_RS02445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLCG_RS02450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLCG_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
SLCG_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
SLCG_RS02495	COG2172	sigma factor antagonist activity
SLCG_RS02510	COG1252	NADH dehydrogenase
SLCG_RS02555	COG1982	Orn Lys Arg decarboxylase major
SLCG_RS02565	COG0477	Major facilitator Superfamily
SLCG_RS02600	COG5002	protein histidine kinase activity
SLCG_RS02605	COG0745	RESPONSE REGULATOR receiver
SLCG_RS02620	COG3189	MarR family transcriptional regulator
SLCG_RS02640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLCG_RS02660	COG0492	ferredoxin-NADP+ reductase activity
SLCG_RS02665	COG3852	Histidine kinase
SLCG_RS02675	COG2197	response regulator
SLCG_RS02695	COG3345	alpha-galactosidase
SLCG_RS02700	COG1846	Transcriptional regulator
SLCG_RS02700	COG1940	carbohydrate kinase activity
SLCG_RS02710	COG2340	Cysteine-rich secretory protein family
SLCG_RS02725	COG0142	geranyltranstransferase activity
SLCG_RS02730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SLCG_RS02735	COG0515	serine threonine protein kinase
SLCG_RS02735	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLCG_RS02745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS02775	COG0667	Aldo Keto reductase
SLCG_RS02805	COG0328	RNA-DNA hybrid ribonuclease activity
SLCG_RS02815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLCG_RS02825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLCG_RS02845	COG0596	Alpha beta hydrolase
SLCG_RS02850	COG0740	serine-type endopeptidase activity
SLCG_RS02855	COG0740	serine-type endopeptidase activity
SLCG_RS02860	COG1396	sequence-specific DNA binding
SLCG_RS02865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SLCG_RS02870	COG1191	sigma factor activity
SLCG_RS02895	COG0515	serine threonine protein kinase
SLCG_RS02895	COG2815	serine threonine protein kinase
SLCG_RS02905	COG1131	(ABC) transporter
SLCG_RS02905	COG1716	ATPase activity
SLCG_RS02905	COG0842	Transport permease protein
SLCG_RS02925	COG0667	Aldo Keto reductase
SLCG_RS02930	COG0583	DNA-binding transcription factor activity
SLCG_RS02940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLCG_RS02945	COG0346	lactoylglutathione lyase activity
SLCG_RS02950	COG0412	Dienelactone hydrolase
SLCG_RS02960	COG0667	Aldo Keto reductase
SLCG_RS02970	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SLCG_RS02970	COG4106	trans-aconitate 2-methyltransferase activity
SLCG_RS02975	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS02995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS03105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SLCG_RS03110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLCG_RS03115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLCG_RS03135	COG3387	PFAM Glycoside hydrolase 15-related
SLCG_RS03155	COG0367	asparagine synthase
SLCG_RS03210	COG0589	response to stress
SLCG_RS03235	COG1024	Enoyl-CoA hydratase
SLCG_RS03255	COG2267	carboxylic ester hydrolase activity
SLCG_RS03310	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS03315	COG2366	antibiotic biosynthetic process
SLCG_RS03345	COG2188	Transcriptional regulator
SLCG_RS03360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLCG_RS03370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SLCG_RS03385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLCG_RS03390	COG1126	abc transporter atp-binding protein
SLCG_RS03395	COG0765	amino acid transport
SLCG_RS03405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS03410	COG0745	RESPONSE REGULATOR receiver
SLCG_RS03465	COG1609	Transcriptional regulator
SLCG_RS03470	COG1653	transport
SLCG_RS03485	COG0366	Alpha amylase catalytic
SLCG_RS03505	COG5297	Belongs to the glycosyl hydrolase family 6
SLCG_RS03525	COG0300	oxidoreductase activity
SLCG_RS03535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SLCG_RS03540	COG4585	Histidine kinase
SLCG_RS03545	COG2197	response regulator
SLCG_RS03575	COG1522	sequence-specific DNA binding
SLCG_RS03615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS03620	COG0778	Nitroreductase
SLCG_RS03645	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SLCG_RS03650	COG0738	Major facilitator superfamily
SLCG_RS03665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SLCG_RS03700	COG3250	beta-galactosidase activity
SLCG_RS03710	COG2755	lipolytic protein G-D-S-L family
SLCG_RS03735	COG2070	2-Nitropropane dioxygenase
SLCG_RS03740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLCG_RS03760	COG0515	serine threonine protein kinase
SLCG_RS03760	COG2815	serine threonine protein kinase
SLCG_RS03775	COG4171	peptide transport system, permease
SLCG_RS03800	COG0789	Transcriptional regulator
SLCG_RS03840	COG1309	transcriptional regulator
SLCG_RS03850	COG0300	oxidoreductase activity
SLCG_RS03855	COG0604	alcohol dehydrogenase
SLCG_RS03855	COG3321	synthase
SLCG_RS03880	COG2226	methyltransferase
SLCG_RS03920	COG1609	Transcriptional regulator
SLCG_RS03930	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLCG_RS03940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLCG_RS03955	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLCG_RS03965	COG1609	Transcriptional regulator
SLCG_RS03970	COG1609	Transcriptional regulator
SLCG_RS03995	COG1609	Transcriptional regulator
SLCG_RS04000	COG1175	transmembrane transport
SLCG_RS04005	COG0395	ABC-type sugar transport system, permease component
SLCG_RS04015	COG0673	inositol 2-dehydrogenase activity
SLCG_RS04035	COG2319	Wd-40 repeat
SLCG_RS04035	COG4249	Peptidase C14 caspase catalytic subunit p20
SLCG_RS04070	COG0604	alcohol dehydrogenase
SLCG_RS04070	COG3321	synthase
SLCG_RS04110	COG1404	Belongs to the peptidase S8 family
SLCG_RS04130	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS04165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLCG_RS04175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLCG_RS04200	COG0137	argininosuccinate synthase activity
SLCG_RS04225	COG2376	Dihydroxyacetone kinase
SLCG_RS04235	COG1461	Dihydroxyacetone kinase
SLCG_RS04275	COG1309	transcriptional regulator
SLCG_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS04315	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLCG_RS04315	COG1902	pentaerythritol trinitrate reductase activity
SLCG_RS04335	COG0475	glutathione-regulated potassium exporter activity
SLCG_RS04385	COG2890	protein-(glutamine-N5) methyltransferase activity
SLCG_RS04405	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLCG_RS04425	COG3458	cephalosporin-C deacetylase activity
SLCG_RS04430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLCG_RS04435	COG2226	methyltransferase
SLCG_RS04450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS04455	COG3284	Transcriptional regulator
SLCG_RS04465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SLCG_RS04470	COG1686	Belongs to the peptidase S11 family
SLCG_RS04475	COG5650	phosphatidylinositol metabolic process
SLCG_RS04485	COG2066	Belongs to the glutaminase family
SLCG_RS04500	COG1113	amino acid transport
SLCG_RS04505	COG2186	Transcriptional regulator
SLCG_RS04510	COG1968	undecaprenyl-diphosphatase activity
SLCG_RS04515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLCG_RS04520	COG1993	acr, cog1993
SLCG_RS04525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLCG_RS04575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLCG_RS04580	COG1116	anion transmembrane transporter activity
SLCG_RS04605	COG0277	FAD linked oxidase domain protein
SLCG_RS04620	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS04675	COG0443	Heat shock 70 kDa protein
SLCG_RS04720	COG3386	PFAM SMP-30 Gluconolaconase
SLCG_RS04730	COG0800	Aldolase
SLCG_RS04750	COG0129	dihydroxy-acid dehydratase activity
SLCG_RS04755	COG1063	alcohol dehydrogenase
SLCG_RS04795	COG0395	ABC-type sugar transport system, permease component
SLCG_RS04800	COG1175	transmembrane transport
SLCG_RS04810	COG1609	Transcriptional regulator
SLCG_RS04820	COG3940	Belongs to the glycosyl hydrolase 43 family
SLCG_RS04835	COG1819	glycosyl
SLCG_RS04840	COG3973	AAA domain
SLCG_RS04850	COG2814	Major facilitator Superfamily
SLCG_RS04860	COG1846	Transcriptional regulator
SLCG_RS04865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLCG_RS04880	COG1937	Protein conserved in bacteria
SLCG_RS04885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SLCG_RS04905	COG2186	Transcriptional regulator
SLCG_RS04915	COG0134	indole-3-glycerol-phosphate synthase activity
SLCG_RS04920	COG0723	plastoquinol--plastocyanin reductase activity
SLCG_RS04920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS04930	COG0667	Aldo Keto reductase
SLCG_RS04945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLCG_RS04960	COG3842	ATPase activity
SLCG_RS04970	COG3608	succinylglutamate desuccinylase aspartoacylase
SLCG_RS04995	COG0247	lactate metabolic process
SLCG_RS04995	COG0277	FAD linked oxidase domain protein
SLCG_RS05000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLCG_RS05020	COG2409	Drug exporters of the RND superfamily
SLCG_RS05025	COG0477	Major facilitator Superfamily
SLCG_RS05035	COG2197	response regulator
SLCG_RS05040	COG3851	Histidine kinase
SLCG_RS05045	COG2409	Drug exporters of the RND superfamily
SLCG_RS05050	COG0789	Transcriptional regulator
SLCG_RS05065	COG0640	Transcriptional regulator
SLCG_RS05070	COG2072	flavoprotein involved in K transport
SLCG_RS05075	COG0798	PFAM Bile acid sodium symporter
SLCG_RS05085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLCG_RS05110	COG1090	epimerase
SLCG_RS05125	COG0604	alcohol dehydrogenase
SLCG_RS05140	COG2188	Transcriptional regulator
SLCG_RS05155	COG0596	Alpha beta hydrolase
SLCG_RS05165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLCG_RS05170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLCG_RS05180	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS05185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLCG_RS05205	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SLCG_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS05250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SLCG_RS05255	COG1215	transferase activity, transferring glycosyl groups
SLCG_RS05290	COG1349	DNA-binding transcription factor activity
SLCG_RS05305	COG2208	phosphoserine phosphatase activity
SLCG_RS05305	COG1366	Belongs to the anti-sigma-factor antagonist family
SLCG_RS05305	COG2172	sigma factor antagonist activity
SLCG_RS05315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLCG_RS05330	COG0577	efflux transmembrane transporter activity
SLCG_RS05370	COG0698	ribose 5-phosphate isomerase
SLCG_RS05375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SLCG_RS05390	COG1940	carbohydrate kinase activity
SLCG_RS05400	COG2813	Specifically methylates the guanine in position
SLCG_RS05420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLCG_RS05425	COG1349	DNA-binding transcription factor activity
SLCG_RS05430	COG3387	PFAM Glycoside hydrolase 15-related
SLCG_RS05435	COG0477	Major facilitator Superfamily
SLCG_RS05455	COG0395	ABC-type sugar transport system, permease component
SLCG_RS05460	COG1175	transmembrane transport
SLCG_RS05500	COG2197	response regulator
SLCG_RS05525	COG4565	transcriptional regulatory protein
SLCG_RS05550	COG1316	TRANSCRIPTIONal
SLCG_RS05600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS05605	COG1126	abc transporter atp-binding protein
SLCG_RS05615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLCG_RS05620	COG3835	regulator
SLCG_RS05630	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SLCG_RS05645	COG1609	Transcriptional regulator
SLCG_RS05650	COG0667	Aldo Keto reductase
SLCG_RS05665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLCG_RS05685	COG2186	Transcriptional regulator
SLCG_RS05690	COG2267	carboxylic ester hydrolase activity
SLCG_RS05710	COG0444	Belongs to the ABC transporter superfamily
SLCG_RS05715	COG4608	Belongs to the ABC transporter superfamily
SLCG_RS05730	COG1454	alcohol dehydrogenase
SLCG_RS05735	COG3485	protocatechuate 3,4-dioxygenase
SLCG_RS05745	COG3284	Transcriptional regulator
SLCG_RS05780	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SLCG_RS05785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLCG_RS05800	COG1349	DNA-binding transcription factor activity
SLCG_RS05840	COG0477	Major facilitator Superfamily
SLCG_RS05845	COG4948	Mandelate Racemase Muconate Lactonizing
SLCG_RS05850	COG2610	gluconate transmembrane transporter activity
SLCG_RS05855	COG1414	Transcriptional regulator
SLCG_RS05875	COG2223	nitrite transmembrane transporter activity
SLCG_RS05895	COG0596	Alpha beta hydrolase
SLCG_RS05910	COG0789	Transcriptional regulator
SLCG_RS05915	COG0659	secondary active sulfate transmembrane transporter activity
SLCG_RS05925	COG3795	YCII-related domain
SLCG_RS05930	COG4941	Belongs to the sigma-70 factor family
SLCG_RS05935	COG0583	DNA-binding transcription factor activity
SLCG_RS05955	COG1802	Transcriptional regulator
SLCG_RS05985	COG0748	coenzyme F420 binding
SLCG_RS05995	COG1733	regulation of RNA biosynthetic process
SLCG_RS06010	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SLCG_RS06015	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SLCG_RS06020	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SLCG_RS06035	COG0745	RESPONSE REGULATOR receiver
SLCG_RS06040	COG2205	protein histidine kinase activity
SLCG_RS06050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLCG_RS06050	COG0515	serine threonine protein kinase
SLCG_RS06085	COG1609	Transcriptional regulator
SLCG_RS06105	COG1131	(ABC) transporter
SLCG_RS06140	COG0488	(ABC) transporter
SLCG_RS06155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLCG_RS06165	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS06180	COG0596	Alpha beta hydrolase
SLCG_RS06190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS06205	COG0697	spore germination
SLCG_RS06220	COG0673	inositol 2-dehydrogenase activity
SLCG_RS06230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLCG_RS06235	COG0583	DNA-binding transcription factor activity
SLCG_RS06240	COG2851	Citrate transporter
SLCG_RS06280	COG2197	response regulator
SLCG_RS06285	COG4585	Histidine kinase
SLCG_RS06290	COG2409	Drug exporters of the RND superfamily
SLCG_RS06295	COG3903	Transcriptional regulator
SLCG_RS06295	COG3629	intracellular signal transduction
SLCG_RS06310	COG0445	tRNA wobble uridine modification
SLCG_RS06325	COG4608	Belongs to the ABC transporter superfamily
SLCG_RS06330	COG0444	Belongs to the ABC transporter superfamily
SLCG_RS06335	COG0601	transmembrane transport
SLCG_RS06340	COG0747	negative chemotaxis
SLCG_RS06345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLCG_RS06350	COG1660	Displays ATPase and GTPase activities
SLCG_RS06360	COG1090	epimerase
SLCG_RS06380	COG2815	serine threonine protein kinase
SLCG_RS06380	COG0515	serine threonine protein kinase
SLCG_RS06395	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SLCG_RS06420	COG0204	Acyl-transferase
SLCG_RS06455	COG0584	glycerophosphoryl diester phosphodiesterase
SLCG_RS06505	COG0671	phosphoesterase, PA-phosphatase related
SLCG_RS06515	COG1309	transcriptional regulator
SLCG_RS06535	COG0493	'glutamate synthase
SLCG_RS06545	COG0640	Transcriptional regulator
SLCG_RS06550	COG1902	pentaerythritol trinitrate reductase activity
SLCG_RS06555	COG3509	depolymerase
SLCG_RS06575	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS06610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLCG_RS06625	COG2706	6-phosphogluconolactonase activity
SLCG_RS06640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLCG_RS06650	COG1404	Belongs to the peptidase S8 family
SLCG_RS06660	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLCG_RS06660	COG1672	PFAM Archaeal ATPase
SLCG_RS06700	COG1653	transport
SLCG_RS06705	COG1175	transmembrane transport
SLCG_RS06710	COG0395	ABC-type sugar transport system, permease component
SLCG_RS06715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLCG_RS06720	COG4948	Mandelate Racemase Muconate Lactonizing
SLCG_RS06765	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SLCG_RS06795	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SLCG_RS06815	COG0246	Mannitol dehydrogenase
SLCG_RS06820	COG0477	Major facilitator Superfamily
SLCG_RS06825	COG1063	alcohol dehydrogenase
SLCG_RS06845	COG0714	Associated with various cellular activities
SLCG_RS06890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS06940	COG0657	acetylesterase activity
SLCG_RS06945	COG0432	Pfam Uncharacterised protein family UPF0047
SLCG_RS06950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLCG_RS06955	COG1116	anion transmembrane transporter activity
SLCG_RS06975	COG1132	(ABC) transporter
SLCG_RS06985	COG1301	dicarboxylic acid transport
SLCG_RS07000	COG1132	(ABC) transporter
SLCG_RS07005	COG1132	(ABC) transporter
SLCG_RS07015	COG0254	rRNA binding
SLCG_RS07030	COG1946	Acyl-CoA thioesterase
SLCG_RS07040	COG2018	Roadblock/LC7 domain
SLCG_RS07095	COG3239	Fatty acid desaturase
SLCG_RS07100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLCG_RS07120	COG2115	Belongs to the xylose isomerase family
SLCG_RS07130	COG1846	Transcriptional regulator
SLCG_RS07130	COG1940	carbohydrate kinase activity
SLCG_RS07145	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS07175	COG0602	queuosine metabolic process
SLCG_RS07190	COG1609	Transcriptional regulator
SLCG_RS07200	COG1175	transmembrane transport
SLCG_RS07210	COG1472	Belongs to the glycosyl hydrolase 3 family
SLCG_RS07220	COG0129	dihydroxy-acid dehydratase activity
SLCG_RS07265	COG3693	PFAM glycoside hydrolase, family 10
SLCG_RS07285	COG0019	diaminopimelate decarboxylase activity
SLCG_RS07290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLCG_RS07295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLCG_RS07305	COG1169	isochorismate synthase
SLCG_RS07310	COG1021	2,3-dihydroxybenzoate-AMP ligase
SLCG_RS07315	COG3433	isochorismatase activity
SLCG_RS07315	COG2226	methyltransferase
SLCG_RS07315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLCG_RS07320	COG3433	isochorismatase activity
SLCG_RS07320	COG2226	methyltransferase
SLCG_RS07320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLCG_RS07355	COG1132	(ABC) transporter
SLCG_RS07355	COG2375	cellular response to nickel ion
SLCG_RS07365	COG0477	Major facilitator Superfamily
SLCG_RS07375	COG4172	Belongs to the ABC transporter superfamily
SLCG_RS07390	COG1703	isobutyryl-CoA mutase activity
SLCG_RS07390	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS07390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS07400	COG3833	ABC-type maltose transport systems, permease component
SLCG_RS07410	COG2182	Extracellular solute-binding protein
SLCG_RS07430	COG4585	Histidine kinase
SLCG_RS07460	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS07465	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS07480	COG0492	ferredoxin-NADP+ reductase activity
SLCG_RS07485	COG1793	dna ligase
SLCG_RS07505	COG3424	synthase
SLCG_RS07510	COG2124	cytochrome p450
SLCG_RS07520	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS07530	COG0242	peptide deformylase activity
SLCG_RS07535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLCG_RS07540	COG3442	glutamine amidotransferase
SLCG_RS07545	COG0205	6-phosphofructokinase activity
SLCG_RS07570	COG3275	phosphorelay sensor kinase activity
SLCG_RS07575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLCG_RS07585	COG3279	Response regulator of the LytR AlgR family
SLCG_RS07590	COG1522	sequence-specific DNA binding
SLCG_RS07595	COG1834	amidinotransferase
SLCG_RS07600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLCG_RS07645	COG0829	nickel cation binding
SLCG_RS07650	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SLCG_RS07660	COG0804	urea catabolic process
SLCG_RS07665	COG0832	Belongs to the urease beta subunit family
SLCG_RS07670	COG0831	urea catabolic process
SLCG_RS07675	COG1309	transcriptional regulator
SLCG_RS07705	COG1940	carbohydrate kinase activity
SLCG_RS07725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SLCG_RS07740	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS07750	COG1126	abc transporter atp-binding protein
SLCG_RS07755	COG0765	amino acid transport
SLCG_RS07760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLCG_RS07765	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS07775	COG0251	oxidation-reduction process
SLCG_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS07800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS07820	COG0740	serine-type endopeptidase activity
SLCG_RS07840	COG1280	lysine exporter protein (LysE YggA)
SLCG_RS07845	COG0583	DNA-binding transcription factor activity
SLCG_RS07870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SLCG_RS07875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLCG_RS07880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SLCG_RS07895	COG2226	methyltransferase
SLCG_RS07915	COG1136	(ABC) transporter
SLCG_RS07915	COG0577	efflux transmembrane transporter activity
SLCG_RS07930	COG0456	acetyltransferase
SLCG_RS07955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLCG_RS07960	COG3663	DNA glycosylase
SLCG_RS07980	COG4585	Histidine kinase
SLCG_RS07985	COG2197	response regulator
SLCG_RS07990	COG1940	carbohydrate kinase activity
SLCG_RS07995	COG2188	Transcriptional regulator
SLCG_RS08000	COG1595	DNA-templated transcription, initiation
SLCG_RS08010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS08045	COG1522	sequence-specific DNA binding
SLCG_RS08050	COG0419	ATPase involved in DNA repair
SLCG_RS08055	COG0420	3'-5' exonuclease activity
SLCG_RS08090	COG1739	Uncharacterized protein family UPF0029
SLCG_RS08100	COG0215	cysteine-tRNA ligase activity
SLCG_RS08105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLCG_RS08110	COG3842	ATPase activity
SLCG_RS08120	COG1176	ABC-type spermidine putrescine transport system, permease component I
SLCG_RS08130	COG2188	Transcriptional regulator
SLCG_RS08140	COG1278	Cold shock
SLCG_RS08150	COG1832	CoA-binding protein
SLCG_RS08155	COG0531	amino acid
SLCG_RS08165	COG0640	Transcriptional regulator
SLCG_RS08190	COG0110	maltose O-acetyltransferase activity
SLCG_RS08240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLCG_RS08265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLCG_RS08275	COG0183	Belongs to the thiolase family
SLCG_RS08285	COG1968	undecaprenyl-diphosphatase activity
SLCG_RS08305	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SLCG_RS08310	COG0673	inositol 2-dehydrogenase activity
SLCG_RS08315	COG2318	DinB family
SLCG_RS08330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLCG_RS08335	COG0747	negative chemotaxis
SLCG_RS08380	COG0697	spore germination
SLCG_RS08425	COG1695	Transcriptional regulator
SLCG_RS08430	COG2226	methyltransferase
SLCG_RS08465	COG1609	Transcriptional regulator
SLCG_RS08475	COG0395	ABC-type sugar transport system, permease component
SLCG_RS08490	COG3507	Belongs to the glycosyl hydrolase 43 family
SLCG_RS08520	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLCG_RS08520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLCG_RS08530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SLCG_RS08570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLCG_RS08605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLCG_RS08620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS08625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLCG_RS08650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLCG_RS08660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLCG_RS08665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLCG_RS08700	COG0531	amino acid
SLCG_RS08725	COG2814	Major facilitator Superfamily
SLCG_RS08730	COG4336	lyase activity
SLCG_RS08735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SLCG_RS08740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SLCG_RS08745	COG1984	allophanate hydrolase subunit 2
SLCG_RS08750	COG2755	lipolytic protein G-D-S-L family
SLCG_RS08755	COG0438	transferase activity, transferring glycosyl groups
SLCG_RS08790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS08795	COG2364	Membrane
SLCG_RS08805	COG2270	Major facilitator Superfamily
SLCG_RS08820	COG1216	Glycosyl transferase, family 2
SLCG_RS08845	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS08895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SLCG_RS08900	COG0140	phosphoribosyl-ATP diphosphatase activity
SLCG_RS08905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SLCG_RS08910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLCG_RS08910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLCG_RS08915	COG3201	nicotinamide mononucleotide transporter
SLCG_RS08925	COG1846	Transcriptional regulator
SLCG_RS08925	COG1940	carbohydrate kinase activity
SLCG_RS08935	COG2233	PERMEase
SLCG_RS08955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLCG_RS08980	COG0531	amino acid
SLCG_RS09005	COG3903	Transcriptional regulator
SLCG_RS09005	COG3629	intracellular signal transduction
SLCG_RS09015	COG2390	Transcriptional regulator
SLCG_RS09020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SLCG_RS09025	COG2409	Drug exporters of the RND superfamily
SLCG_RS09035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SLCG_RS09050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLCG_RS09060	COG1758	RNA polymerase activity
SLCG_RS09065	COG0194	GDP metabolic process
SLCG_RS09075	COG0284	orotidine-5'-phosphate decarboxylase activity
SLCG_RS09080	COG0167	dihydroorotate dehydrogenase activity
SLCG_RS09085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SLCG_RS09090	COG0505	Belongs to the CarA family
SLCG_RS09100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLCG_RS09105	COG0540	Belongs to the ATCase OTCase family
SLCG_RS09110	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SLCG_RS09120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SLCG_RS09125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SLCG_RS09130	COG0006	proline dipeptidase activity
SLCG_RS09140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SLCG_RS09145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SLCG_RS09150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SLCG_RS09155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SLCG_RS09170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SLCG_RS09175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SLCG_RS09195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SLCG_RS09210	COG1131	(ABC) transporter
SLCG_RS09220	COG4585	Histidine kinase
SLCG_RS09225	COG2197	response regulator
SLCG_RS09230	COG0124	histidyl-tRNA synthetase
SLCG_RS09240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SLCG_RS09355	COG0598	Magnesium transport protein CorA
SLCG_RS09395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLCG_RS09400	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS09425	COG0385	Bile acid
SLCG_RS09440	COG1742	UPF0060 membrane protein
SLCG_RS09470	COG3940	Belongs to the glycosyl hydrolase 43 family
SLCG_RS09475	COG3940	Belongs to the glycosyl hydrolase 43 family
SLCG_RS09480	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SLCG_RS09500	COG2252	PERMEase
SLCG_RS09505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLCG_RS09530	COG1802	Transcriptional regulator
SLCG_RS09575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLCG_RS09585	COG1162	GTPase activity
SLCG_RS09605	COG0277	FAD linked oxidase domain protein
SLCG_RS09620	COG1175	transmembrane transport
SLCG_RS09635	COG1131	(ABC) transporter
SLCG_RS09650	COG0738	Major facilitator superfamily
SLCG_RS09700	COG2755	lipolytic protein G-D-S-L family
SLCG_RS09735	COG0531	amino acid
SLCG_RS09740	COG2040	homocysteine
SLCG_RS09745	COG1609	Transcriptional regulator
SLCG_RS09770	COG0395	ABC-type sugar transport system, permease component
SLCG_RS09775	COG1175	transmembrane transport
SLCG_RS09785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLCG_RS09790	COG1609	Transcriptional regulator
SLCG_RS09800	COG1175	transmembrane transport
SLCG_RS09810	COG3507	Belongs to the glycosyl hydrolase 43 family
SLCG_RS09925	COG2423	ornithine cyclodeaminase activity
SLCG_RS09930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLCG_RS09935	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS09965	COG0175	sulfate reduction
SLCG_RS09970	COG0529	Catalyzes the synthesis of activated sulfate
SLCG_RS09995	COG1116	anion transmembrane transporter activity
SLCG_RS10000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLCG_RS10055	COG2205	protein histidine kinase activity
SLCG_RS10060	COG0745	RESPONSE REGULATOR receiver
SLCG_RS10080	COG1175	transmembrane transport
SLCG_RS10105	COG0583	DNA-binding transcription factor activity
SLCG_RS10185	COG1280	lysine exporter protein (LysE YggA)
SLCG_RS10190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLCG_RS10200	COG0504	CTP synthase activity
SLCG_RS10240	COG1309	transcriptional regulator
SLCG_RS10255	COG0702	epimerase
SLCG_RS10260	COG1404	Belongs to the peptidase S8 family
SLCG_RS10285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLCG_RS10290	COG1316	TRANSCRIPTIONal
SLCG_RS10295	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLCG_RS10300	COG0640	Transcriptional regulator
SLCG_RS10365	COG1940	carbohydrate kinase activity
SLCG_RS10370	COG2755	lipolytic protein G-D-S-L family
SLCG_RS10385	COG2018	Roadblock/LC7 domain
SLCG_RS10405	COG1174	glycine betaine transport
SLCG_RS10430	COG2124	cytochrome p450
SLCG_RS10455	COG0745	RESPONSE REGULATOR receiver
SLCG_RS10460	COG2205	protein histidine kinase activity
SLCG_RS10465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SLCG_RS10470	COG5002	protein histidine kinase activity
SLCG_RS10475	COG0745	RESPONSE REGULATOR receiver
SLCG_RS10520	COG0601	transmembrane transport
SLCG_RS10525	COG0747	negative chemotaxis
SLCG_RS10545	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLCG_RS10550	COG4821	SIS domain
SLCG_RS10555	COG1737	Transcriptional regulator
SLCG_RS10575	COG1175	transmembrane transport
SLCG_RS10580	COG0395	ABC-type sugar transport system, permease component
SLCG_RS10600	COG1472	Belongs to the glycosyl hydrolase 3 family
SLCG_RS10615	COG0640	Transcriptional regulator
SLCG_RS10620	COG2814	Major facilitator Superfamily
SLCG_RS10625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLCG_RS10630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SLCG_RS10665	COG0330	HflC and HflK could
SLCG_RS10675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS10675	COG0723	plastoquinol--plastocyanin reductase activity
SLCG_RS10680	COG0726	polysaccharide deacetylase
SLCG_RS10695	COG4152	abc transporter atp-binding protein
SLCG_RS10705	COG3220	belongs to the UPF0276 family
SLCG_RS10725	COG3253	May function as heme-dependent peroxidase
SLCG_RS10740	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLCG_RS10765	COG4585	Histidine kinase
SLCG_RS10770	COG2197	response regulator
SLCG_RS10785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLCG_RS10790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLCG_RS10810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLCG_RS10825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLCG_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS10845	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS10855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLCG_RS10860	COG2226	methyltransferase
SLCG_RS10875	COG2197	response regulator
SLCG_RS10880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SLCG_RS10895	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SLCG_RS10905	COG1175	transmembrane transport
SLCG_RS10915	COG3250	beta-galactosidase activity
SLCG_RS10920	COG1609	Transcriptional regulator
SLCG_RS10925	COG0183	Belongs to the thiolase family
SLCG_RS10930	COG1024	Enoyl-CoA hydratase
SLCG_RS10930	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS10960	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SLCG_RS10970	COG0531	amino acid
SLCG_RS10975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLCG_RS10980	COG4214	carbohydrate transport
SLCG_RS10990	COG4213	ABC transporter substrate-binding protein
SLCG_RS10995	COG1940	carbohydrate kinase activity
SLCG_RS11000	COG0395	ABC-type sugar transport system, permease component
SLCG_RS11005	COG1175	transmembrane transport
SLCG_RS11010	COG1653	transport
SLCG_RS11040	COG1653	transport
SLCG_RS11045	COG0395	ABC-type sugar transport system, permease component
SLCG_RS11050	COG4209	transmembrane transport
SLCG_RS11055	COG3458	cephalosporin-C deacetylase activity
SLCG_RS11065	COG3739	integral membrane protein
SLCG_RS11070	COG0438	transferase activity, transferring glycosyl groups
SLCG_RS11080	COG2205	protein histidine kinase activity
SLCG_RS11090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SLCG_RS11100	COG2226	methyltransferase
SLCG_RS11110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLCG_RS11155	COG1902	pentaerythritol trinitrate reductase activity
SLCG_RS11160	COG1024	Enoyl-CoA hydratase
SLCG_RS11170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SLCG_RS11175	COG2235	arginine
SLCG_RS11200	COG0475	glutathione-regulated potassium exporter activity
SLCG_RS11210	COG2255	four-way junction helicase activity
SLCG_RS11220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SLCG_RS11230	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS11235	COG0156	8-amino-7-oxononanoate synthase activity
SLCG_RS11240	COG1132	(ABC) transporter
SLCG_RS11245	COG1132	(ABC) transporter
SLCG_RS11250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLCG_RS11255	COG0367	asparagine synthase
SLCG_RS11305	COG1131	(ABC) transporter
SLCG_RS11315	COG1216	Glycosyl transferase, family 2
SLCG_RS11345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SLCG_RS11350	COG1799	cell septum assembly
SLCG_RS11355	COG0243	molybdopterin cofactor binding
SLCG_RS11405	COG0657	acetylesterase activity
SLCG_RS11410	COG0640	Transcriptional regulator
SLCG_RS11435	COG2304	oxidoreductase activity
SLCG_RS11460	COG1879	ABC-type sugar transport system periplasmic component
SLCG_RS11465	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS11475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLCG_RS11480	COG1869	D-ribose catabolic process
SLCG_RS11515	COG4974	Belongs to the 'phage' integrase family
SLCG_RS11560	COG1201	RNA secondary structure unwinding
SLCG_RS11580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SLCG_RS11585	COG0531	amino acid
SLCG_RS11590	COG0569	domain protein
SLCG_RS11620	COG1136	(ABC) transporter
SLCG_RS11620	COG0577	efflux transmembrane transporter activity
SLCG_RS11635	COG0756	dUTP diphosphatase activity
SLCG_RS11660	COG2205	protein histidine kinase activity
SLCG_RS11665	COG0745	RESPONSE REGULATOR receiver
SLCG_RS11675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SLCG_RS11710	COG1435	thymidine kinase activity
SLCG_RS11725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLCG_RS11725	COG1042	CoA-binding domain protein
SLCG_RS11725	COG0045	succinate-CoA ligase (ADP-forming) activity
SLCG_RS11735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLCG_RS11740	COG1802	Transcriptional regulator
SLCG_RS11755	COG0612	Peptidase, M16
SLCG_RS11760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLCG_RS11785	COG0372	Belongs to the citrate synthase family
SLCG_RS11800	COG3290	protein histidine kinase activity
SLCG_RS11805	COG4565	transcriptional regulatory protein
SLCG_RS11810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLCG_RS11820	COG2197	response regulator
SLCG_RS11835	COG0187	DNA topoisomerase II activity
SLCG_RS11850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLCG_RS11855	COG1802	Transcriptional regulator
SLCG_RS11880	COG0514	ATP-dependent DNA helicase (RecQ)
SLCG_RS11895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SLCG_RS11920	COG0588	phosphoglycerate mutase activity
SLCG_RS11935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SLCG_RS11940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SLCG_RS11945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SLCG_RS11985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SLCG_RS11995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLCG_RS12000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SLCG_RS12010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SLCG_RS12030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLCG_RS12035	COG0488	(ABC) transporter
SLCG_RS12040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS12055	COG2197	response regulator
SLCG_RS12060	COG3851	Histidine kinase
SLCG_RS12075	COG2358	TRAP transporter, solute receptor (TAXI family
SLCG_RS12080	COG2205	protein histidine kinase activity
SLCG_RS12085	COG0745	RESPONSE REGULATOR receiver
SLCG_RS12090	COG1126	abc transporter atp-binding protein
SLCG_RS12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLCG_RS12100	COG0765	amino acid transport
SLCG_RS12105	COG0765	amino acid transport
SLCG_RS12110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLCG_RS12125	COG0577	efflux transmembrane transporter activity
SLCG_RS12145	COG0628	permease
SLCG_RS12170	COG1201	RNA secondary structure unwinding
SLCG_RS12175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLCG_RS12180	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS12190	COG1396	sequence-specific DNA binding
SLCG_RS12195	COG1058	Belongs to the CinA family
SLCG_RS12195	COG1546	Belongs to the CinA family
SLCG_RS12205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLCG_RS12215	COG1674	ftsk spoiiie
SLCG_RS12225	COG4999	Histidine kinase
SLCG_RS12225	COG3850	Histidine kinase
SLCG_RS12225	COG3437	response regulator, receiver
SLCG_RS12225	COG2205	protein histidine kinase activity
SLCG_RS12235	COG2208	phosphoserine phosphatase activity
SLCG_RS12235	COG2770	Histidine kinase
SLCG_RS12275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLCG_RS12280	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SLCG_RS12300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SLCG_RS12305	COG0612	Peptidase, M16
SLCG_RS12310	COG1185	polyribonucleotide nucleotidyltransferase activity
SLCG_RS12315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SLCG_RS12335	COG1674	ftsk spoiiie
SLCG_RS12395	COG1404	Belongs to the peptidase S8 family
SLCG_RS12415	COG0455	bacterial-type flagellum organization
SLCG_RS12430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SLCG_RS12435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SLCG_RS12445	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SLCG_RS12460	COG0779	Required for maturation of 30S ribosomal subunits
SLCG_RS12485	COG0442	prolyl-tRNA aminoacylation
SLCG_RS12500	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLCG_RS12505	COG0750	zinc metalloprotease
SLCG_RS12510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SLCG_RS12520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLCG_RS12520	COG0515	serine threonine protein kinase
SLCG_RS12565	COG0395	ABC-type sugar transport system, permease component
SLCG_RS12570	COG4209	transmembrane transport
SLCG_RS12575	COG1653	transport
SLCG_RS12590	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS12615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS12620	COG1177	transmembrane transport
SLCG_RS12625	COG1176	ABC-type spermidine putrescine transport system, permease component I
SLCG_RS12630	COG3842	ATPase activity
SLCG_RS12660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLCG_RS12665	COG0584	glycerophosphoryl diester phosphodiesterase
SLCG_RS12705	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS12715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLCG_RS12720	COG1136	(ABC) transporter
SLCG_RS12750	COG3842	ATPase activity
SLCG_RS12755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SLCG_RS12765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SLCG_RS12810	COG0575	Belongs to the CDS family
SLCG_RS12815	COG0233	cytoplasmic translational termination
SLCG_RS12820	COG0528	UMP kinase activity
SLCG_RS12825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SLCG_RS12830	COG0052	Belongs to the universal ribosomal protein uS2 family
SLCG_RS12845	COG1191	sigma factor activity
SLCG_RS12860	COG0792	nuclease activity
SLCG_RS12880	COG0681	Belongs to the peptidase S26 family
SLCG_RS12885	COG0681	Belongs to the peptidase S26 family
SLCG_RS12895	COG0335	large ribosomal subunit rRNA binding
SLCG_RS12900	COG0336	Belongs to the RNA methyltransferase TrmD family
SLCG_RS12905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SLCG_RS12910	COG1837	Belongs to the UPF0109 family
SLCG_RS12915	COG0228	four-way junction DNA binding
SLCG_RS12925	COG0442	prolyl-tRNA aminoacylation
SLCG_RS12935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLCG_RS12945	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SLCG_RS12980	COG0477	Major facilitator Superfamily
SLCG_RS12985	COG1196	nuclear chromosome segregation
SLCG_RS13000	COG1254	Belongs to the acylphosphatase family
SLCG_RS13005	COG2340	Cysteine-rich secretory protein family
SLCG_RS13010	COG1733	regulation of RNA biosynthetic process
SLCG_RS13015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLCG_RS13020	COG0571	ribonuclease III activity
SLCG_RS13025	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SLCG_RS13040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SLCG_RS13055	COG0326	Molecular chaperone. Has ATPase activity
SLCG_RS13065	COG1461	Dihydroxyacetone kinase
SLCG_RS13070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLCG_RS13075	COG0351	phosphomethylpyrimidine kinase
SLCG_RS13095	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLCG_RS13100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SLCG_RS13110	COG1920	GTP binding
SLCG_RS13120	COG0776	regulation of translation
SLCG_RS13130	COG0066	3-isopropylmalate dehydratase activity
SLCG_RS13135	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SLCG_RS13140	COG1414	Transcriptional regulator
SLCG_RS13180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SLCG_RS13185	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLCG_RS13195	COG5002	protein histidine kinase activity
SLCG_RS13200	COG2018	Roadblock/LC7 domain
SLCG_RS13220	COG2018	Roadblock/LC7 domain
SLCG_RS13240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLCG_RS13245	COG5492	domain, Protein
SLCG_RS13250	COG2353	YceI-like domain
SLCG_RS13295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLCG_RS13315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLCG_RS13320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SLCG_RS13325	COG0473	3-isopropylmalate dehydrogenase activity
SLCG_RS13345	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS13350	COG0506	proline dehydrogenase activity
SLCG_RS13375	COG0747	negative chemotaxis
SLCG_RS13380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLCG_RS13390	COG4608	Belongs to the ABC transporter superfamily
SLCG_RS13400	COG0477	Major facilitator Superfamily
SLCG_RS13405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLCG_RS13410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SLCG_RS13415	COG0440	acetolactate synthase activity
SLCG_RS13430	COG5001	Diguanylate cyclase
SLCG_RS13440	COG0667	Aldo Keto reductase
SLCG_RS13445	COG2133	pyrroloquinoline quinone binding
SLCG_RS13455	COG1672	PFAM Archaeal ATPase
SLCG_RS13455	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLCG_RS13470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLCG_RS13475	COG2409	Drug exporters of the RND superfamily
SLCG_RS13485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLCG_RS13490	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLCG_RS13500	COG0154	amidase activity
SLCG_RS13505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLCG_RS13515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLCG_RS13525	COG4221	oxidoreductase activity
SLCG_RS13530	COG1611	Belongs to the LOG family
SLCG_RS13540	COG0482	sulfurtransferase activity
SLCG_RS13545	COG3023	N-Acetylmuramoyl-L-alanine amidase
SLCG_RS13575	COG2378	regulation of single-species biofilm formation
SLCG_RS13590	COG2860	membrane
SLCG_RS13595	COG4608	Belongs to the ABC transporter superfamily
SLCG_RS13600	COG0444	Belongs to the ABC transporter superfamily
SLCG_RS13635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLCG_RS13640	COG0509	glycine decarboxylation via glycine cleavage system
SLCG_RS13645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLCG_RS13650	COG1760	l-serine dehydratase
SLCG_RS13680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLCG_RS13680	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SLCG_RS13700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLCG_RS13700	COG3321	synthase
SLCG_RS13700	COG0300	oxidoreductase activity
SLCG_RS13700	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS13700	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS13705	COG3409	Peptidoglycan-binding domain 1 protein
SLCG_RS13705	COG3757	hydrolase, family 25
SLCG_RS13780	COG2197	response regulator
SLCG_RS13785	COG4585	Histidine kinase
SLCG_RS13800	COG1132	(ABC) transporter
SLCG_RS13805	COG1132	(ABC) transporter
SLCG_RS13810	COG1132	(ABC) transporter
SLCG_RS13815	COG1132	(ABC) transporter
SLCG_RS13835	COG0058	SHG alpha-glucan phosphorylase activity
SLCG_RS13845	COG0366	Alpha amylase catalytic
SLCG_RS13855	COG3281	Trehalose synthase
SLCG_RS13860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLCG_RS13875	COG2124	cytochrome p450
SLCG_RS13890	COG3118	belongs to the thioredoxin family
SLCG_RS13890	COG0492	ferredoxin-NADP+ reductase activity
SLCG_RS13900	COG1522	sequence-specific DNA binding
SLCG_RS13910	COG0667	Aldo Keto reductase
SLCG_RS13920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLCG_RS13945	COG0477	Major facilitator Superfamily
SLCG_RS13985	COG0612	Peptidase, M16
SLCG_RS13995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SLCG_RS14005	COG1132	(ABC) transporter
SLCG_RS14030	COG1301	dicarboxylic acid transport
SLCG_RS14035	COG3290	protein histidine kinase activity
SLCG_RS14040	COG4565	transcriptional regulatory protein
SLCG_RS14045	COG1653	transport
SLCG_RS14050	COG1175	transmembrane transport
SLCG_RS14055	COG0395	ABC-type sugar transport system, permease component
SLCG_RS14090	COG0205	6-phosphofructokinase activity
SLCG_RS14095	COG0857	belongs to the CobB CobQ family
SLCG_RS14095	COG0280	phosphate acetyltransferase
SLCG_RS14100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SLCG_RS14140	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS14140	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS14230	COG0745	RESPONSE REGULATOR receiver
SLCG_RS14245	COG0183	Belongs to the thiolase family
SLCG_RS14250	COG0346	lactoylglutathione lyase activity
SLCG_RS14275	COG1131	(ABC) transporter
SLCG_RS14310	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SLCG_RS14325	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS14350	COG2197	response regulator
SLCG_RS14365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SLCG_RS14370	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SLCG_RS14375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SLCG_RS14380	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SLCG_RS14385	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLCG_RS14390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SLCG_RS14395	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLCG_RS14415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLCG_RS14420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLCG_RS14430	COG2890	protein-(glutamine-N5) methyltransferase activity
SLCG_RS14435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SLCG_RS14440	COG0254	rRNA binding
SLCG_RS14455	COG0083	homoserine kinase activity
SLCG_RS14460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SLCG_RS14465	COG0460	homoserine dehydrogenase
SLCG_RS14470	COG0019	diaminopimelate decarboxylase activity
SLCG_RS14475	COG0018	arginyl-trna synthetase
SLCG_RS14480	COG0745	RESPONSE REGULATOR receiver
SLCG_RS14590	COG2816	NAD+ diphosphatase activity
SLCG_RS14660	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SLCG_RS14665	COG1793	dna ligase
SLCG_RS14665	COG3285	dna ligase
SLCG_RS14690	COG2205	protein histidine kinase activity
SLCG_RS14720	COG1309	transcriptional regulator
SLCG_RS14800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SLCG_RS14815	COG0745	RESPONSE REGULATOR receiver
SLCG_RS14820	COG2205	protein histidine kinase activity
SLCG_RS14825	COG0567	Dehydrogenase, E1 component
SLCG_RS14825	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLCG_RS14905	COG0604	alcohol dehydrogenase
SLCG_RS14915	COG0281	malic enzyme
SLCG_RS14935	COG1126	abc transporter atp-binding protein
SLCG_RS14940	COG1136	(ABC) transporter
SLCG_RS14940	COG0577	efflux transmembrane transporter activity
SLCG_RS14945	COG1136	(ABC) transporter
SLCG_RS14990	COG2326	polyphosphate kinase activity
SLCG_RS15005	COG4977	sequence-specific DNA binding
SLCG_RS15025	COG4941	Belongs to the sigma-70 factor family
SLCG_RS15060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLCG_RS15070	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SLCG_RS15100	COG1597	lipid kinase activity
SLCG_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS15125	COG0363	glucosamine-6-phosphate deaminase activity
SLCG_RS15130	COG1472	Belongs to the glycosyl hydrolase 3 family
SLCG_RS15135	COG0395	ABC-type sugar transport system, permease component
SLCG_RS15140	COG1175	transmembrane transport
SLCG_RS15145	COG2182	Extracellular solute-binding protein
SLCG_RS15150	COG2188	Transcriptional regulator
SLCG_RS15155	COG1966	Carbon starvation protein
SLCG_RS15205	COG2124	cytochrome p450
SLCG_RS15215	COG0242	peptide deformylase activity
SLCG_RS15230	COG2199	diguanylate cyclase activity
SLCG_RS15230	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SLCG_RS15260	COG5662	AntiSigma factor
SLCG_RS15265	COG1595	DNA-templated transcription, initiation
SLCG_RS15275	COG2135	peptidase activity
SLCG_RS15285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SLCG_RS15290	COG1162	GTPase activity
SLCG_RS15305	COG0483	inositol monophosphate 1-phosphatase activity
SLCG_RS15350	COG1615	UPF0182 protein
SLCG_RS15360	COG3480	Lon protease (S16) C-terminal proteolytic domain
SLCG_RS15415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SLCG_RS15455	COG0210	DNA helicase
SLCG_RS15505	COG0297	glycogen (starch) synthase activity
SLCG_RS15515	COG0601	transmembrane transport
SLCG_RS15520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLCG_RS15525	COG0747	negative chemotaxis
SLCG_RS15580	COG1432	Conserved Protein
SLCG_RS15590	COG2095	MarC family integral membrane protein
SLCG_RS15605	COG2814	Major facilitator Superfamily
SLCG_RS15615	COG0598	Magnesium transport protein CorA
SLCG_RS15650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLCG_RS15655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLCG_RS15665	COG1595	DNA-templated transcription, initiation
SLCG_RS15680	COG1024	Enoyl-CoA hydratase
SLCG_RS15685	COG2818	Glycosylase
SLCG_RS15695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SLCG_RS15710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLCG_RS15745	COG2197	response regulator
SLCG_RS15750	COG4585	Histidine kinase
SLCG_RS15780	COG3485	protocatechuate 3,4-dioxygenase
SLCG_RS15785	COG0735	belongs to the Fur family
SLCG_RS15790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLCG_RS15795	COG1490	D-aminoacyl-tRNA deacylase activity
SLCG_RS15805	COG4552	Acetyltransferase involved in intracellular survival and related
SLCG_RS15815	COG2188	Transcriptional regulator
SLCG_RS15825	COG2188	Transcriptional regulator
SLCG_RS15830	COG0546	phosphoglycolate phosphatase activity
SLCG_RS15855	COG3973	AAA domain
SLCG_RS15865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SLCG_RS15880	COG0300	oxidoreductase activity
SLCG_RS15885	COG4221	oxidoreductase activity
SLCG_RS15900	COG2226	methyltransferase
SLCG_RS15915	COG0494	nUDIX hydrolase
SLCG_RS15960	COG0438	transferase activity, transferring glycosyl groups
SLCG_RS15990	COG0588	phosphoglycerate mutase activity
SLCG_RS16030	COG1404	Belongs to the peptidase S8 family
SLCG_RS16080	COG1329	Transcriptional regulator
SLCG_RS16090	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SLCG_RS16095	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SLCG_RS16100	COG0215	cysteine-tRNA ligase activity
SLCG_RS16125	COG3842	ATPase activity
SLCG_RS16240	COG5001	Diguanylate cyclase
SLCG_RS16240	COG3300	MHYT domain
SLCG_RS16250	COG1105	Belongs to the carbohydrate kinase PfkB family
SLCG_RS16255	COG1228	amidohydrolase
SLCG_RS16265	COG1653	transport
SLCG_RS16285	COG0463	Glycosyl transferase, family 2
SLCG_RS16305	COG0459	protein refolding
SLCG_RS16335	COG2319	Wd-40 repeat
SLCG_RS16335	COG4249	Peptidase C14 caspase catalytic subunit p20
SLCG_RS16365	COG0667	Aldo Keto reductase
SLCG_RS16390	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SLCG_RS16395	COG1737	Transcriptional regulator
SLCG_RS16420	COG0326	Molecular chaperone. Has ATPase activity
SLCG_RS16440	COG3142	Participates in the control of copper homeostasis
SLCG_RS16445	COG3973	AAA domain
SLCG_RS16455	COG1061	Type III restriction enzyme res subunit
SLCG_RS16470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SLCG_RS16490	COG1278	Cold shock
SLCG_RS16495	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLCG_RS16500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SLCG_RS16510	COG2814	Major facilitator Superfamily
SLCG_RS16550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLCG_RS16560	COG2252	PERMEase
SLCG_RS16590	COG0667	Aldo Keto reductase
SLCG_RS16640	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SLCG_RS16645	COG0596	Alpha beta hydrolase
SLCG_RS16650	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SLCG_RS16655	COG0277	FAD linked oxidase domain protein
SLCG_RS16655	COG0247	lactate metabolic process
SLCG_RS16690	COG2226	methyltransferase
SLCG_RS16745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLCG_RS16760	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS16775	COG0259	pyridoxamine-phosphate oxidase activity
SLCG_RS16800	COG4821	SIS domain
SLCG_RS16810	COG2945	thiolester hydrolase activity
SLCG_RS16810	COG0596	Alpha beta hydrolase
SLCG_RS16820	COG1131	(ABC) transporter
SLCG_RS16860	COG1595	DNA-templated transcription, initiation
SLCG_RS16885	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS16890	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS16915	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS16945	COG1024	Enoyl-CoA hydratase
SLCG_RS16955	COG2072	flavoprotein involved in K transport
SLCG_RS16985	COG0259	pyridoxamine-phosphate oxidase activity
SLCG_RS17000	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS17010	COG1280	lysine exporter protein (LysE YggA)
SLCG_RS17015	COG1522	sequence-specific DNA binding
SLCG_RS17020	COG1309	transcriptional regulator
SLCG_RS17030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLCG_RS17030	COG0515	serine threonine protein kinase
SLCG_RS17040	COG0596	Alpha beta hydrolase
SLCG_RS17045	COG1024	Enoyl-CoA hydratase
SLCG_RS17060	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS17070	COG3903	Transcriptional regulator
SLCG_RS17070	COG3629	intracellular signal transduction
SLCG_RS17085	COG2197	response regulator
SLCG_RS17110	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SLCG_RS17115	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS17120	COG2267	carboxylic ester hydrolase activity
SLCG_RS17145	COG0640	Transcriptional regulator
SLCG_RS17215	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLCG_RS17240	COG1404	Belongs to the peptidase S8 family
SLCG_RS17265	COG1686	Belongs to the peptidase S11 family
SLCG_RS17290	COG0386	Belongs to the glutathione peroxidase family
SLCG_RS17305	COG3629	intracellular signal transduction
SLCG_RS17305	COG3903	Transcriptional regulator
SLCG_RS17335	COG4585	Histidine kinase
SLCG_RS17340	COG2197	response regulator
SLCG_RS17350	COG2375	cellular response to nickel ion
SLCG_RS17350	COG1132	(ABC) transporter
SLCG_RS17355	COG1132	(ABC) transporter
SLCG_RS17360	COG1879	ABC-type sugar transport system periplasmic component
SLCG_RS17370	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS17375	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS17430	COG0492	ferredoxin-NADP+ reductase activity
SLCG_RS17435	COG3852	Histidine kinase
SLCG_RS17485	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS17500	COG0596	Alpha beta hydrolase
SLCG_RS17520	COG1309	transcriptional regulator
SLCG_RS17535	COG0477	Major facilitator Superfamily
SLCG_RS17560	COG1024	Enoyl-CoA hydratase
SLCG_RS17560	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS17570	COG1414	Transcriptional regulator
SLCG_RS17590	COG1846	Transcriptional regulator
SLCG_RS17595	COG3384	dioxygenase
SLCG_RS17600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLCG_RS17610	COG0477	Major facilitator Superfamily
SLCG_RS17615	COG1349	DNA-binding transcription factor activity
SLCG_RS17640	COG1376	ErfK ybiS ycfS ynhG family protein
SLCG_RS17645	COG3191	aminopeptidase activity
SLCG_RS17655	COG1970	mechanosensitive ion channel activity
SLCG_RS17665	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SLCG_RS17695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SLCG_RS17700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLCG_RS17710	COG0315	cyclic pyranopterin monophosphate synthase activity
SLCG_RS17715	COG0521	Mo-molybdopterin cofactor biosynthetic process
SLCG_RS17715	COG0315	cyclic pyranopterin monophosphate synthase activity
SLCG_RS17735	COG0577	efflux transmembrane transporter activity
SLCG_RS17740	COG1136	(ABC) transporter
SLCG_RS17740	COG0577	efflux transmembrane transporter activity
SLCG_RS17745	COG4585	Histidine kinase
SLCG_RS17750	COG2197	response regulator
SLCG_RS17755	COG0454	-acetyltransferase
SLCG_RS17760	COG0708	Exodeoxyribonuclease III
SLCG_RS17775	COG2072	flavoprotein involved in K transport
SLCG_RS17780	COG2267	carboxylic ester hydrolase activity
SLCG_RS17785	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS17795	COG0793	Belongs to the peptidase S41A family
SLCG_RS17795	COG4946	Tricorn protease homolog
SLCG_RS17805	COG2409	Drug exporters of the RND superfamily
SLCG_RS17820	COG0456	acetyltransferase
SLCG_RS17835	COG0442	prolyl-tRNA aminoacylation
SLCG_RS17855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLCG_RS17860	COG1122	ATPase activity
SLCG_RS17870	COG0310	cobalt ion transport
SLCG_RS17910	COG0084	hydrolase, TatD family'
SLCG_RS17915	COG3584	3D domain protein
SLCG_RS17915	COG3583	domain protein
SLCG_RS17920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SLCG_RS17925	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SLCG_RS17930	COG0488	(ABC) transporter
SLCG_RS17970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SLCG_RS18005	COG2197	response regulator
SLCG_RS18015	COG4106	trans-aconitate 2-methyltransferase activity
SLCG_RS18030	COG1309	transcriptional regulator
SLCG_RS18040	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SLCG_RS18055	COG0193	aminoacyl-tRNA hydrolase activity
SLCG_RS18060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SLCG_RS18065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLCG_RS18070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SLCG_RS18085	COG4585	Histidine kinase
SLCG_RS18115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLCG_RS18140	COG0477	Major facilitator Superfamily
SLCG_RS18145	COG1136	(ABC) transporter
SLCG_RS18150	COG0577	efflux transmembrane transporter activity
SLCG_RS18195	COG2124	cytochrome p450
SLCG_RS18200	COG1652	LysM domain
SLCG_RS18210	COG0148	phosphopyruvate hydratase activity
SLCG_RS18230	COG1252	NADH dehydrogenase
SLCG_RS18235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLCG_RS18240	COG0577	efflux transmembrane transporter activity
SLCG_RS18245	COG1136	(ABC) transporter
SLCG_RS18285	COG0183	Belongs to the thiolase family
SLCG_RS18290	COG2755	lipolytic protein G-D-S-L family
SLCG_RS18310	COG1174	glycine betaine transport
SLCG_RS18315	COG1174	glycine betaine transport
SLCG_RS18365	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SLCG_RS18370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLCG_RS18380	COG1228	amidohydrolase
SLCG_RS18410	COG1191	sigma factor activity
SLCG_RS18415	COG1366	Belongs to the anti-sigma-factor antagonist family
SLCG_RS18450	COG3104	oligopeptide transport
SLCG_RS18455	COG0745	RESPONSE REGULATOR receiver
SLCG_RS18460	COG2205	protein histidine kinase activity
SLCG_RS18475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SLCG_RS18485	COG0745	RESPONSE REGULATOR receiver
SLCG_RS18525	COG1276	copper resistance
SLCG_RS18535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLCG_RS18560	COG1316	TRANSCRIPTIONal
SLCG_RS18570	COG1316	TRANSCRIPTIONal
SLCG_RS18575	COG0463	Glycosyl transferase, family 2
SLCG_RS18580	COG1316	TRANSCRIPTIONal
SLCG_RS18585	COG1316	TRANSCRIPTIONal
SLCG_RS18595	COG1316	TRANSCRIPTIONal
SLCG_RS18620	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SLCG_RS18620	COG0778	Nitroreductase
SLCG_RS18625	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLCG_RS18660	COG1620	l-lactate permease
SLCG_RS18665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLCG_RS18670	COG2835	tetraacyldisaccharide 4'-kinase activity
SLCG_RS18680	COG1482	cell wall glycoprotein biosynthetic process
SLCG_RS18695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLCG_RS18695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SLCG_RS18695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SLCG_RS18700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SLCG_RS18745	COG0714	Associated with various cellular activities
SLCG_RS18765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SLCG_RS18770	COG0745	RESPONSE REGULATOR receiver
SLCG_RS18775	COG5002	protein histidine kinase activity
SLCG_RS18780	COG0823	Involved in the tonB-independent uptake of proteins
SLCG_RS18790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SLCG_RS18795	COG2197	response regulator
SLCG_RS18800	COG3214	Protein conserved in bacteria
SLCG_RS18810	COG0653	protein targeting
SLCG_RS18840	COG1134	teichoic acid transport
SLCG_RS18840	COG1388	LysM domain
SLCG_RS18870	COG1846	Transcriptional regulator
SLCG_RS18875	COG1764	response to oxidative stress
SLCG_RS18890	COG1216	Glycosyl transferase, family 2
SLCG_RS18895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLCG_RS18900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLCG_RS18905	COG0395	ABC-type sugar transport system, permease component
SLCG_RS18910	COG1175	transmembrane transport
SLCG_RS18915	COG1653	transport
SLCG_RS18925	COG0515	serine threonine protein kinase
SLCG_RS18930	COG0515	serine threonine protein kinase
SLCG_RS18935	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SLCG_RS18950	COG2884	Cell division ATP-binding protein ftsE
SLCG_RS18960	COG0793	Belongs to the peptidase S41A family
SLCG_RS18965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SLCG_RS18980	COG1472	Belongs to the glycosyl hydrolase 3 family
SLCG_RS18990	COG1501	Belongs to the glycosyl hydrolase 31 family
SLCG_RS18995	COG0395	ABC-type sugar transport system, permease component
SLCG_RS19000	COG4209	transmembrane transport
SLCG_RS19015	COG0583	DNA-binding transcription factor activity
SLCG_RS19035	COG2223	nitrite transmembrane transporter activity
SLCG_RS19065	COG3973	AAA domain
SLCG_RS19075	COG0776	regulation of translation
SLCG_RS19080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLCG_RS19085	COG1678	Uncharacterized ACR, COG1678
SLCG_RS19100	COG1175	transmembrane transport
SLCG_RS19105	COG0395	ABC-type sugar transport system, permease component
SLCG_RS19110	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLCG_RS19125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLCG_RS19155	COG3654	unkown
SLCG_RS19195	COG1174	glycine betaine transport
SLCG_RS19205	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SLCG_RS19230	COG0277	FAD linked oxidase domain protein
SLCG_RS19265	COG1335	isochorismatase
SLCG_RS19275	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SLCG_RS19285	COG1113	amino acid transport
SLCG_RS19320	COG1234	tRNA 3'-trailer cleavage
SLCG_RS19325	COG1263	PTS System
SLCG_RS19330	COG1263	PTS System
SLCG_RS19335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SLCG_RS19340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SLCG_RS19350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SLCG_RS19385	COG2076	Multidrug Resistance protein
SLCG_RS19390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLCG_RS19420	COG2733	membrane
SLCG_RS19450	COG0071	Belongs to the small heat shock protein (HSP20) family
SLCG_RS19555	COG0706	membrane insertase activity
SLCG_RS19570	COG4702	Belongs to the UPF0303 family
SLCG_RS19575	COG0673	inositol 2-dehydrogenase activity
SLCG_RS19580	COG1940	carbohydrate kinase activity
SLCG_RS19640	COG0671	phosphoesterase, PA-phosphatase related
SLCG_RS19655	COG1295	ribonuclease BN
SLCG_RS19660	COG1686	Belongs to the peptidase S11 family
SLCG_RS19670	COG1408	metallophosphoesterase
SLCG_RS19690	COG2205	protein histidine kinase activity
SLCG_RS19695	COG0745	RESPONSE REGULATOR receiver
SLCG_RS19700	COG2409	Drug exporters of the RND superfamily
SLCG_RS19755	COG1053	succinate dehydrogenase
SLCG_RS19765	COG2009	succinate dehydrogenase
SLCG_RS19810	COG1595	DNA-templated transcription, initiation
SLCG_RS19825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS19825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS19845	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SLCG_RS19875	COG0463	Glycosyl transferase, family 2
SLCG_RS19890	COG1216	Glycosyl transferase, family 2
SLCG_RS19905	COG2089	acid synthase
SLCG_RS19915	COG2226	methyltransferase
SLCG_RS19925	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLCG_RS19925	COG1473	amidohydrolase
SLCG_RS19930	COG1744	ABC transporter substrate-binding protein PnrA-like
SLCG_RS19935	COG3845	ABC transporter
SLCG_RS19940	COG4603	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS19945	COG1079	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS19980	COG2814	Major facilitator Superfamily
SLCG_RS19985	COG0583	DNA-binding transcription factor activity
SLCG_RS19995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLCG_RS20020	COG2205	protein histidine kinase activity
SLCG_RS20025	COG0745	RESPONSE REGULATOR receiver
SLCG_RS20030	COG1595	DNA-templated transcription, initiation
SLCG_RS20035	COG0572	uridine kinase
SLCG_RS20050	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS20070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLCG_RS20100	COG4770	biotin carboxylase activity
SLCG_RS20110	COG0424	maF-like protein
SLCG_RS20125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLCG_RS20135	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLCG_RS20145	COG1024	Enoyl-CoA hydratase
SLCG_RS20155	COG2986	histidine ammonia-lyase
SLCG_RS20185	COG1136	(ABC) transporter
SLCG_RS20195	COG1404	Belongs to the peptidase S8 family
SLCG_RS20210	COG1064	alcohol dehydrogenase
SLCG_RS20215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS20220	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS20225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS20260	COG3835	regulator
SLCG_RS20270	COG5549	protein import
SLCG_RS20270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLCG_RS20275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLCG_RS20300	COG2255	four-way junction helicase activity
SLCG_RS20305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SLCG_RS20320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SLCG_RS20330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLCG_RS20345	COG2255	four-way junction helicase activity
SLCG_RS20350	COG1331	Highly conserved protein containing a thioredoxin domain
SLCG_RS20365	COG1215	transferase activity, transferring glycosyl groups
SLCG_RS20375	COG1309	transcriptional regulator
SLCG_RS20380	COG0477	Major facilitator Superfamily
SLCG_RS20390	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SLCG_RS20435	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SLCG_RS20450	COG1414	Transcriptional regulator
SLCG_RS20455	COG0251	oxidation-reduction process
SLCG_RS20460	COG2610	gluconate transmembrane transporter activity
SLCG_RS20565	COG2045	Belongs to the ComB family
SLCG_RS20605	COG2894	cell division
SLCG_RS20635	COG4585	Histidine kinase
SLCG_RS20685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLCG_RS20695	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SLCG_RS20700	COG0741	lytic transglycosylase activity
SLCG_RS20720	COG1136	(ABC) transporter
SLCG_RS20740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLCG_RS20785	COG0114	fumarate hydratase activity
SLCG_RS20790	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SLCG_RS20790	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SLCG_RS20815	COG0778	Nitroreductase
SLCG_RS20820	COG1722	exodeoxyribonuclease VII activity
SLCG_RS20825	COG1570	exodeoxyribonuclease VII activity
SLCG_RS20835	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SLCG_RS20850	COG0012	GTP binding
SLCG_RS20865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLCG_RS20870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLCG_RS20875	COG0646	methionine synthase
SLCG_RS20875	COG1410	methionine synthase
SLCG_RS20920	COG1917	Cupin 2, conserved barrel domain protein
SLCG_RS20935	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLCG_RS20935	COG1672	PFAM Archaeal ATPase
SLCG_RS20945	COG0778	Nitroreductase
SLCG_RS20975	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SLCG_RS20985	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS21000	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SLCG_RS21020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS21030	COG2197	response regulator
SLCG_RS21105	COG1053	succinate dehydrogenase
SLCG_RS21130	COG1217	gtp-binding protein TYPA
SLCG_RS21145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLCG_RS21155	COG4608	Belongs to the ABC transporter superfamily
SLCG_RS21165	COG4608	Belongs to the ABC transporter superfamily
SLCG_RS21175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLCG_RS21180	COG0601	transmembrane transport
SLCG_RS21185	COG0747	negative chemotaxis
SLCG_RS21210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLCG_RS21225	COG1131	(ABC) transporter
SLCG_RS21245	COG2897	thiosulfate sulfurtransferase activity
SLCG_RS21275	COG0745	RESPONSE REGULATOR receiver
SLCG_RS21280	COG1609	Transcriptional regulator
SLCG_RS21285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLCG_RS21295	COG0745	RESPONSE REGULATOR receiver
SLCG_RS21325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLCG_RS21335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS21350	COG1132	(ABC) transporter
SLCG_RS21360	COG0737	Belongs to the 5'-nucleotidase family
SLCG_RS21365	COG0456	acetyltransferase
SLCG_RS21395	COG1725	Transcriptional regulator
SLCG_RS21400	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SLCG_RS21415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SLCG_RS21425	COG0494	nUDIX hydrolase
SLCG_RS21425	COG0406	alpha-ribazole phosphatase activity
SLCG_RS21445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SLCG_RS21450	COG0306	phosphate transporter
SLCG_RS21460	COG1937	Protein conserved in bacteria
SLCG_RS21475	COG0277	FAD linked oxidase domain protein
SLCG_RS21480	COG0671	phosphoesterase, PA-phosphatase related
SLCG_RS21485	COG0741	lytic transglycosylase activity
SLCG_RS21485	COG1196	nuclear chromosome segregation
SLCG_RS21485	COG0739	heme binding
SLCG_RS21490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLCG_RS21490	COG0515	serine threonine protein kinase
SLCG_RS21510	COG4221	oxidoreductase activity
SLCG_RS21560	COG4585	Histidine kinase
SLCG_RS21565	COG2197	response regulator
SLCG_RS21605	COG1252	NADH dehydrogenase
SLCG_RS21635	COG0579	oxidoreductase
SLCG_RS21640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SLCG_RS21670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SLCG_RS21670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SLCG_RS21680	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLCG_RS21685	COG2197	response regulator
SLCG_RS21695	COG3409	Peptidoglycan-binding domain 1 protein
SLCG_RS21745	COG1278	Cold shock
SLCG_RS21765	COG0513	Belongs to the DEAD box helicase family
SLCG_RS21770	COG1278	Cold shock
SLCG_RS21805	COG0513	Belongs to the DEAD box helicase family
SLCG_RS21840	COG1643	Atp-dependent helicase
SLCG_RS21865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SLCG_RS21875	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SLCG_RS21910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLCG_RS21915	COG0047	phosphoribosylformylglycinamidine synthase activity
SLCG_RS21920	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLCG_RS21955	COG2197	response regulator
SLCG_RS21965	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SLCG_RS21980	COG0151	Belongs to the GarS family
SLCG_RS22055	COG2188	Transcriptional regulator
SLCG_RS22065	COG2188	Transcriptional regulator
SLCG_RS22135	COG0702	epimerase
SLCG_RS22150	COG0745	RESPONSE REGULATOR receiver
SLCG_RS22170	COG4249	Peptidase C14 caspase catalytic subunit p20
SLCG_RS22170	COG2319	Wd-40 repeat
SLCG_RS22195	COG2409	Drug exporters of the RND superfamily
SLCG_RS22200	COG2197	response regulator
SLCG_RS22205	COG4585	Histidine kinase
SLCG_RS22225	COG1276	copper resistance
SLCG_RS22225	COG2372	response to copper ion
SLCG_RS22230	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS22250	COG1132	(ABC) transporter
SLCG_RS22250	COG2375	cellular response to nickel ion
SLCG_RS22285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SLCG_RS22335	COG1191	sigma factor activity
SLCG_RS22340	COG1191	sigma factor activity
SLCG_RS22355	COG0477	Major facilitator Superfamily
SLCG_RS22360	COG2353	YceI-like domain
SLCG_RS22385	COG3467	pyridoxamine 5'-phosphate
SLCG_RS22395	COG0477	Major facilitator Superfamily
SLCG_RS22400	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLCG_RS22410	COG2205	protein histidine kinase activity
SLCG_RS22415	COG0745	RESPONSE REGULATOR receiver
SLCG_RS22425	COG1090	epimerase
SLCG_RS22430	COG1595	DNA-templated transcription, initiation
SLCG_RS22445	COG1846	Transcriptional regulator
SLCG_RS22495	COG1309	transcriptional regulator
SLCG_RS22500	COG2814	Major facilitator Superfamily
SLCG_RS22505	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS22515	COG1595	DNA-templated transcription, initiation
SLCG_RS22560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLCG_RS22580	COG0653	protein targeting
SLCG_RS22600	COG0006	proline dipeptidase activity
SLCG_RS22605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS22615	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SLCG_RS22650	COG2837	iron assimilation
SLCG_RS22665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SLCG_RS22670	COG0561	phosphatase activity
SLCG_RS22715	COG0789	Transcriptional regulator
SLCG_RS22720	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SLCG_RS22735	COG0561	phosphatase activity
SLCG_RS22750	COG4988	ABC transporter
SLCG_RS22755	COG1294	oxidase, subunit
SLCG_RS22760	COG1271	oxidase subunit
SLCG_RS22765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLCG_RS22770	COG1609	Transcriptional regulator
SLCG_RS22785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SLCG_RS22810	COG0662	Cupin 2, conserved barrel domain protein
SLCG_RS22815	COG1950	PFAM Membrane protein of
SLCG_RS22820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLCG_RS22825	COG0626	cystathionine gamma-synthase activity
SLCG_RS22855	COG2814	Major facilitator Superfamily
SLCG_RS22905	COG0305	Participates in initiation and elongation during chromosome replication
SLCG_RS22915	COG0359	binds to the 23S rRNA
SLCG_RS22920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLCG_RS22925	COG0629	single-stranded DNA binding
SLCG_RS22930	COG0360	Binds together with S18 to 16S ribosomal RNA
SLCG_RS22960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLCG_RS22980	COG0617	tRNA 3'-terminal CCA addition
SLCG_RS22995	COG0515	serine threonine protein kinase
SLCG_RS22995	COG2815	serine threonine protein kinase
SLCG_RS23000	COG1595	DNA-templated transcription, initiation
SLCG_RS23010	COG0492	ferredoxin-NADP+ reductase activity
SLCG_RS23015	COG3118	belongs to the thioredoxin family
SLCG_RS23030	COG1192	Involved in chromosome partitioning
SLCG_RS23035	COG0357	Ribosomal RNA small subunit methyltransferase G
SLCG_RS23045	COG0706	membrane insertase activity
SLCG_RS23050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SLCG_RS23055	COG0594	ribonuclease P activity
SLCG_RS23065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SLCG_RS23075	COG0592	DNA-directed DNA polymerase activity
SLCG_RS23080	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SLCG_RS23085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SLCG_RS23090	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SLCG_RS23095	COG0187	DNA topoisomerase II activity
SLCG_RS23100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLCG_RS23155	COG0705	Rhomboid family
SLCG_RS23170	COG3764	Sortase (surface protein transpeptidase)
SLCG_RS23185	COG3764	Sortase (surface protein transpeptidase)
SLCG_RS23190	COG3764	Sortase (surface protein transpeptidase)
SLCG_RS23195	COG0515	serine threonine protein kinase
SLCG_RS23205	COG0768	penicillin binding
SLCG_RS23220	COG1716	ATPase activity
SLCG_RS23225	COG1716	ATPase activity
SLCG_RS23235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SLCG_RS23240	COG1733	regulation of RNA biosynthetic process
SLCG_RS23255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SLCG_RS23285	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS23290	COG1309	transcriptional regulator
SLCG_RS23295	COG1522	sequence-specific DNA binding
SLCG_RS23325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLCG_RS23340	COG3321	synthase
SLCG_RS23340	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS23340	COG0604	alcohol dehydrogenase
SLCG_RS23355	COG0515	serine threonine protein kinase
SLCG_RS23360	COG0515	serine threonine protein kinase
SLCG_RS23385	COG0022	dehydrogenase e1 component
SLCG_RS23390	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLCG_RS23455	COG1362	aminopeptidase activity
SLCG_RS23460	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS23480	COG0477	Major facilitator Superfamily
SLCG_RS23485	COG1741	Belongs to the pirin family
SLCG_RS23500	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SLCG_RS23525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLCG_RS23540	COG3866	Pectate lyase
SLCG_RS23570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLCG_RS23585	COG1289	transmembrane transporter activity
SLCG_RS23595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SLCG_RS23600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS23675	COG0701	Predicted permease
SLCG_RS23695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLCG_RS23700	COG1957	nucleoside hydrolase
SLCG_RS23735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS23795	COG0366	Alpha amylase catalytic
SLCG_RS23850	COG1278	Cold shock
SLCG_RS23875	COG4585	Histidine kinase
SLCG_RS23890	COG4213	ABC transporter substrate-binding protein
SLCG_RS23895	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS23925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLCG_RS23935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLCG_RS23940	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS23955	COG0477	Major facilitator Superfamily
SLCG_RS23970	COG0135	phosphoribosylanthranilate isomerase activity
SLCG_RS24010	COG4948	Mandelate Racemase Muconate Lactonizing
SLCG_RS24050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS24055	COG1595	DNA-templated transcription, initiation
SLCG_RS24090	COG0494	nUDIX hydrolase
SLCG_RS24130	COG4585	Histidine kinase
SLCG_RS24135	COG0586	Pfam SNARE associated Golgi protein
SLCG_RS24145	COG1309	transcriptional regulator
SLCG_RS24150	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS24175	COG0513	Belongs to the DEAD box helicase family
SLCG_RS24180	COG1278	Cold shock
SLCG_RS24195	COG0714	Associated with various cellular activities
SLCG_RS24230	COG3629	intracellular signal transduction
SLCG_RS24230	COG3903	Transcriptional regulator
SLCG_RS24270	COG1376	ErfK ybiS ycfS ynhG family protein
SLCG_RS24285	COG0745	RESPONSE REGULATOR receiver
SLCG_RS24290	COG2205	protein histidine kinase activity
SLCG_RS24325	COG1309	transcriptional regulator
SLCG_RS24330	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS24345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLCG_RS24350	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SLCG_RS24355	COG2080	2 iron, 2 sulfur cluster binding
SLCG_RS24370	COG2197	response regulator
SLCG_RS24375	COG4585	Histidine kinase
SLCG_RS24390	COG4585	Histidine kinase
SLCG_RS24420	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SLCG_RS24450	COG2815	serine threonine protein kinase
SLCG_RS24450	COG0515	serine threonine protein kinase
SLCG_RS24475	COG3693	PFAM glycoside hydrolase, family 10
SLCG_RS24525	COG4591	ABC-type transport system involved in lipoprotein release permease component
SLCG_RS24525	COG1136	(ABC) transporter
SLCG_RS24605	COG0297	glycogen (starch) synthase activity
SLCG_RS24625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLCG_RS24715	COG0717	Belongs to the dCTP deaminase family
SLCG_RS24720	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SLCG_RS24755	COG2181	nitrate reductase activity
SLCG_RS24755	COG0247	lactate metabolic process
SLCG_RS24760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLCG_RS24765	COG0443	Heat shock 70 kDa protein
SLCG_RS24770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SLCG_RS24775	COG0484	heat shock protein binding
SLCG_RS24780	COG0789	Transcriptional regulator
SLCG_RS24810	COG4213	ABC transporter substrate-binding protein
SLCG_RS24815	COG1305	Transglutaminase-like
SLCG_RS24830	COG2311	Membrane
SLCG_RS24840	COG1131	(ABC) transporter
SLCG_RS24855	COG2197	response regulator
SLCG_RS24895	COG0542	response to heat
SLCG_RS24925	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SLCG_RS24940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SLCG_RS24945	COG0191	fructose-bisphosphate aldolase activity
SLCG_RS24950	COG0477	Major facilitator Superfamily
SLCG_RS24965	COG3844	kynureninase activity
SLCG_RS24985	COG4585	Histidine kinase
SLCG_RS24990	COG2197	response regulator
SLCG_RS25000	COG2197	response regulator
SLCG_RS25015	COG3559	Exporter of polyketide antibiotics
SLCG_RS25020	COG1131	(ABC) transporter
SLCG_RS25050	COG4303	Ethanolamine ammonia lyase large subunit
SLCG_RS25065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SLCG_RS25070	COG0737	Belongs to the 5'-nucleotidase family
SLCG_RS25090	COG1802	Transcriptional regulator
SLCG_RS25095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLCG_RS25100	COG0693	protein deglycase activity
SLCG_RS25125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SLCG_RS25130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SLCG_RS25190	COG2205	protein histidine kinase activity
SLCG_RS25195	COG0745	RESPONSE REGULATOR receiver
SLCG_RS25210	COG1595	DNA-templated transcription, initiation
SLCG_RS25240	COG0701	Predicted permease
SLCG_RS25255	COG2249	NAD(P)H dehydrogenase (quinone) activity
SLCG_RS25260	COG2815	serine threonine protein kinase
SLCG_RS25260	COG0515	serine threonine protein kinase
SLCG_RS25280	COG2319	Wd-40 repeat
SLCG_RS25280	COG4249	Peptidase C14 caspase catalytic subunit p20
SLCG_RS25300	COG1309	transcriptional regulator
SLCG_RS25315	COG1408	metallophosphoesterase
SLCG_RS25355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLCG_RS25370	COG0003	Pfam Anion-transporting ATPase
SLCG_RS25395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLCG_RS25425	COG2267	carboxylic ester hydrolase activity
SLCG_RS25435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SLCG_RS25440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLCG_RS25505	COG1205	dead DEAH box helicase
SLCG_RS25505	COG1111	helicase
SLCG_RS25510	COG1366	Belongs to the anti-sigma-factor antagonist family
SLCG_RS25515	COG2172	sigma factor antagonist activity
SLCG_RS25520	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SLCG_RS25545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SLCG_RS25545	COG1754	DNA topoisomerase type I activity
SLCG_RS25550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SLCG_RS25630	COG1733	regulation of RNA biosynthetic process
SLCG_RS25650	COG1136	(ABC) transporter
SLCG_RS25660	COG2197	response regulator
SLCG_RS25700	COG3629	intracellular signal transduction
SLCG_RS25700	COG3903	Transcriptional regulator
SLCG_RS25705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLCG_RS25705	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLCG_RS25735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLCG_RS25740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLCG_RS25745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLCG_RS25750	COG0254	rRNA binding
SLCG_RS25760	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLCG_RS25780	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS25785	COG2318	DinB family
SLCG_RS25805	COG0076	glutamate decarboxylase activity
SLCG_RS25810	COG0789	Transcriptional regulator
SLCG_RS25820	COG0586	Pfam SNARE associated Golgi protein
SLCG_RS25830	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SLCG_RS25835	COG2027	D-alanyl-D-alanine carboxypeptidase
SLCG_RS25845	COG0037	tRNA processing
SLCG_RS25860	COG0302	gtp cyclohydrolase
SLCG_RS25875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SLCG_RS25915	COG0649	NAD binding
SLCG_RS25935	COG1660	Displays ATPase and GTPase activities
SLCG_RS25950	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SLCG_RS25960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SLCG_RS25965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SLCG_RS25975	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SLCG_RS25995	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SLCG_RS26035	COG0739	heme binding
SLCG_RS26045	COG0477	Major facilitator Superfamily
SLCG_RS26060	COG2205	protein histidine kinase activity
SLCG_RS26065	COG0745	RESPONSE REGULATOR receiver
SLCG_RS26075	COG1595	DNA-templated transcription, initiation
SLCG_RS26080	COG1194	a g-specific adenine glycosylase
SLCG_RS26085	COG4585	Histidine kinase
SLCG_RS26105	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SLCG_RS26125	COG0248	Ppx GppA phosphatase
SLCG_RS26130	COG3537	Alpha-1,2-mannosidase
SLCG_RS26135	COG1082	Xylose isomerase domain protein TIM barrel
SLCG_RS26140	COG1309	transcriptional regulator
SLCG_RS26145	COG0129	dihydroxy-acid dehydratase activity
SLCG_RS26155	COG4991	sh3 domain protein
SLCG_RS26170	COG1129	ABC transporter
SLCG_RS26170	COG0842	Transport permease protein
SLCG_RS26180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SLCG_RS26185	COG0180	Tryptophanyl-tRNA synthetase
SLCG_RS26210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLCG_RS26220	COG0738	Major facilitator superfamily
SLCG_RS26225	COG0123	including yeast histone deacetylase and acetoin utilization protein
SLCG_RS26280	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SLCG_RS26285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SLCG_RS26290	COG0181	hydroxymethylbilane synthase activity
SLCG_RS26310	COG0113	porphobilinogen synthase activity
SLCG_RS26325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS26340	COG0018	arginyl-trna synthetase
SLCG_RS26345	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SLCG_RS26365	COG1690	Belongs to the RtcB family
SLCG_RS26395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS26415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLCG_RS26440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS26480	COG2175	clavaminate synthase activity
SLCG_RS26495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SLCG_RS26540	COG0477	Major facilitator Superfamily
SLCG_RS26585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SLCG_RS26590	COG0406	alpha-ribazole phosphatase activity
SLCG_RS26600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLCG_RS26605	COG0785	Cytochrome C biogenesis protein
SLCG_RS26610	COG1333	cytochrome c biogenesis protein
SLCG_RS26615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SLCG_RS26640	COG0789	Transcriptional regulator
SLCG_RS26645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLCG_RS26655	COG0697	spore germination
SLCG_RS26660	COG0583	DNA-binding transcription factor activity
SLCG_RS26670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SLCG_RS26685	COG0163	prenyltransferase activity
SLCG_RS26695	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLCG_RS26700	COG1573	uracil-dna glycosylase
SLCG_RS26710	COG1595	DNA-templated transcription, initiation
SLCG_RS26725	COG1309	transcriptional regulator
SLCG_RS26735	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS26780	COG1053	succinate dehydrogenase
SLCG_RS26800	COG1396	sequence-specific DNA binding
SLCG_RS26805	COG1278	Cold shock
SLCG_RS26810	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLCG_RS26815	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLCG_RS26815	COG0515	serine threonine protein kinase
SLCG_RS26825	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLCG_RS26835	COG3979	chitinase
SLCG_RS26840	COG2226	methyltransferase
SLCG_RS26875	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS26880	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS26885	COG0649	NAD binding
SLCG_RS26895	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLCG_RS26900	COG1034	ATP synthesis coupled electron transport
SLCG_RS26905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLCG_RS26910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS26915	COG0839	Belongs to the complex I subunit 6 family
SLCG_RS26920	COG0713	ATP synthesis coupled electron transport
SLCG_RS26925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLCG_RS26935	COG1007	ATP synthesis coupled electron transport
SLCG_RS26965	COG1175	transmembrane transport
SLCG_RS26970	COG0395	ABC-type sugar transport system, permease component
SLCG_RS26980	COG0561	phosphatase activity
SLCG_RS26985	COG5280	Phage tail tape measure protein TP901
SLCG_RS26985	COG3953	SLT domain
SLCG_RS26995	COG3104	oligopeptide transport
SLCG_RS27000	COG0142	geranyltranstransferase activity
SLCG_RS27015	COG1131	(ABC) transporter
SLCG_RS27055	COG1733	regulation of RNA biosynthetic process
SLCG_RS27070	COG0702	epimerase
SLCG_RS27085	COG1013	pyruvate-flavodoxin oxidoreductase activity
SLCG_RS27090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SLCG_RS27090	COG0674	pyruvate-flavodoxin oxidoreductase activity
SLCG_RS27110	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS27115	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS27120	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS27125	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLCG_RS27130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS27135	COG0839	Belongs to the complex I subunit 6 family
SLCG_RS27140	COG0713	ATP synthesis coupled electron transport
SLCG_RS27145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLCG_RS27150	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS27155	COG1007	ATP synthesis coupled electron transport
SLCG_RS27160	COG0501	Belongs to the peptidase M48B family
SLCG_RS27165	COG3304	Inner membrane component domain
SLCG_RS27185	COG2261	transglycosylase associated protein
SLCG_RS27190	COG1666	GTP binding
SLCG_RS27230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLCG_RS27235	COG2030	dehydratase
SLCG_RS27250	COG0477	Major facilitator Superfamily
SLCG_RS27260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SLCG_RS27270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLCG_RS27275	COG0436	Aminotransferase
SLCG_RS27295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SLCG_RS27300	COG0081	regulation of translation
SLCG_RS27315	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SLCG_RS27320	COG0222	ribosome binding
SLCG_RS27330	COG0085	RNA polymerase activity
SLCG_RS27335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SLCG_RS27375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SLCG_RS27380	COG0049	tRNA binding
SLCG_RS27385	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLCG_RS27390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLCG_RS27405	COG0051	transcription antitermination factor activity, RNA binding
SLCG_RS27410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SLCG_RS27415	COG0088	Forms part of the polypeptide exit tunnel
SLCG_RS27420	COG0089	rRNA binding
SLCG_RS27425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SLCG_RS27430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SLCG_RS27435	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SLCG_RS27440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SLCG_RS27445	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SLCG_RS27450	COG0255	Belongs to the universal ribosomal protein uL29 family
SLCG_RS27455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SLCG_RS27460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SLCG_RS27465	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SLCG_RS27470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SLCG_RS27475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLCG_RS27485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SLCG_RS27490	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SLCG_RS27495	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SLCG_RS27500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SLCG_RS27505	COG1841	ribosomal large subunit assembly
SLCG_RS27510	COG0200	Binds to the 23S rRNA
SLCG_RS27520	COG0563	adenylate kinase activity
SLCG_RS27530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SLCG_RS27535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SLCG_RS27540	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SLCG_RS27545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SLCG_RS27550	COG0202	RNA polymerase activity
SLCG_RS27555	COG0203	ribosomal protein L17
SLCG_RS27560	COG0101	tRNA pseudouridine synthase activity
SLCG_RS27575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SLCG_RS27580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SLCG_RS27585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLCG_RS27595	COG1072	(Pantothenic acid kinase))
SLCG_RS27600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLCG_RS27650	COG0736	holo-[acyl-carrier-protein] synthase activity
SLCG_RS27665	COG0789	Transcriptional regulator
SLCG_RS27670	COG2814	Major facilitator Superfamily
SLCG_RS27690	COG0583	DNA-binding transcription factor activity
SLCG_RS27700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLCG_RS27705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLCG_RS27710	COG1082	Xylose isomerase domain protein TIM barrel
SLCG_RS27725	COG1940	carbohydrate kinase activity
SLCG_RS27750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SLCG_RS27760	COG0802	atpase or kinase
SLCG_RS27780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SLCG_RS27800	COG1609	Transcriptional regulator
SLCG_RS27825	COG4941	Belongs to the sigma-70 factor family
SLCG_RS27835	COG0726	polysaccharide deacetylase
SLCG_RS27840	COG0726	polysaccharide deacetylase
SLCG_RS27845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SLCG_RS27850	COG0459	protein refolding
SLCG_RS27860	COG4221	oxidoreductase activity
SLCG_RS27870	COG0583	DNA-binding transcription factor activity
SLCG_RS27885	COG1595	DNA-templated transcription, initiation
SLCG_RS27895	COG0516	GMP reductase activity
SLCG_RS27910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SLCG_RS27925	COG2815	serine threonine protein kinase
SLCG_RS27925	COG0515	serine threonine protein kinase
SLCG_RS27930	COG0515	serine threonine protein kinase
SLCG_RS27935	COG0515	serine threonine protein kinase
SLCG_RS27940	COG0515	serine threonine protein kinase
SLCG_RS27945	COG0515	serine threonine protein kinase
SLCG_RS27950	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS27985	COG0519	Catalyzes the synthesis of GMP from XMP
SLCG_RS27985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SLCG_RS28030	COG2197	response regulator
SLCG_RS28035	COG0791	NLP P60 protein
SLCG_RS28060	COG0739	heme binding
SLCG_RS28070	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS28070	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS28085	COG0714	Associated with various cellular activities
SLCG_RS28090	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SLCG_RS28100	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SLCG_RS28115	COG0045	succinate-CoA ligase (ADP-forming) activity
SLCG_RS28145	COG0138	bifunctional purine biosynthesis protein purh
SLCG_RS28165	COG2815	serine threonine protein kinase
SLCG_RS28165	COG0515	serine threonine protein kinase
SLCG_RS28175	COG2815	serine threonine protein kinase
SLCG_RS28175	COG0515	serine threonine protein kinase
SLCG_RS28190	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SLCG_RS28210	COG0039	L-malate dehydrogenase activity
SLCG_RS28240	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS28250	COG4175	Glycine betaine
SLCG_RS28250	COG0517	IMP dehydrogenase activity
SLCG_RS28255	COG4176	ABC-type proline glycine betaine transport system permease component
SLCG_RS28270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS28275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS28280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS28300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLCG_RS28335	COG2186	Transcriptional regulator
SLCG_RS28355	COG3397	chitin binding
SLCG_RS28365	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS28380	COG1126	abc transporter atp-binding protein
SLCG_RS28385	COG0765	amino acid transport
SLCG_RS28390	COG0765	amino acid transport
SLCG_RS28425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS28475	COG0406	alpha-ribazole phosphatase activity
SLCG_RS28500	COG0745	RESPONSE REGULATOR receiver
SLCG_RS28505	COG5002	protein histidine kinase activity
SLCG_RS28515	COG0395	ABC-type sugar transport system, permease component
SLCG_RS28550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SLCG_RS28555	COG4977	sequence-specific DNA binding
SLCG_RS28565	COG0589	response to stress
SLCG_RS28575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLCG_RS28605	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLCG_RS28635	COG3409	Peptidoglycan-binding domain 1 protein
SLCG_RS28655	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS28670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLCG_RS28675	COG1309	transcriptional regulator
SLCG_RS28685	COG1946	Acyl-CoA thioesterase
SLCG_RS28700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLCG_RS28710	COG0028	Belongs to the TPP enzyme family
SLCG_RS28715	COG2356	endonuclease I
SLCG_RS28720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLCG_RS28755	COG1472	Belongs to the glycosyl hydrolase 3 family
SLCG_RS28760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SLCG_RS28780	COG1846	Transcriptional regulator
SLCG_RS28780	COG0456	acetyltransferase
SLCG_RS28800	COG3896	Chloramphenicol phosphotransferase-like protein
SLCG_RS28810	COG1609	Transcriptional regulator
SLCG_RS28815	COG0673	inositol 2-dehydrogenase activity
SLCG_RS28835	COG1869	D-ribose catabolic process
SLCG_RS28840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLCG_RS28850	COG1129	ABC transporter
SLCG_RS28870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SLCG_RS28900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLCG_RS28910	COG3718	enzyme involved in inositol metabolism
SLCG_RS28915	COG3962	Belongs to the TPP enzyme family
SLCG_RS28945	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLCG_RS29005	COG0438	transferase activity, transferring glycosyl groups
SLCG_RS29030	COG0438	transferase activity, transferring glycosyl groups
SLCG_RS29085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLCG_RS29130	COG0629	single-stranded DNA binding
SLCG_RS29145	COG1278	Cold shock
SLCG_RS29155	COG0515	serine threonine protein kinase
SLCG_RS29155	COG2815	serine threonine protein kinase
SLCG_RS29180	COG1136	(ABC) transporter
SLCG_RS29180	COG0577	efflux transmembrane transporter activity
SLCG_RS29245	COG1486	melibiose metabolic process
SLCG_RS29250	COG0395	ABC-type sugar transport system, permease component
SLCG_RS29255	COG1175	transmembrane transport
SLCG_RS29260	COG1653	transport
SLCG_RS29270	COG0668	transmembrane transport
SLCG_RS29290	COG1131	(ABC) transporter
SLCG_RS29300	COG1595	DNA-templated transcription, initiation
SLCG_RS29325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLCG_RS29330	COG1846	Transcriptional regulator
SLCG_RS29420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SLCG_RS29445	COG1070	Carbohydrate kinase
SLCG_RS29450	COG0588	phosphoglycerate mutase activity
SLCG_RS29460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SLCG_RS29470	COG1113	amino acid transport
SLCG_RS29490	COG0515	serine threonine protein kinase
SLCG_RS29495	COG1113	amino acid transport
SLCG_RS29500	COG0698	ribose 5-phosphate isomerase
SLCG_RS29510	COG4552	Acetyltransferase involved in intracellular survival and related
SLCG_RS29520	COG1136	(ABC) transporter
SLCG_RS29520	COG0577	efflux transmembrane transporter activity
SLCG_RS29535	COG3594	Acyltransferase
SLCG_RS29555	COG0544	peptidyl-prolyl cis-trans isomerase activity
SLCG_RS29560	COG0740	serine-type endopeptidase activity
SLCG_RS29565	COG0740	serine-type endopeptidase activity
SLCG_RS29570	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SLCG_RS29580	COG0525	valine-tRNA ligase activity
SLCG_RS29585	COG0285	dihydrofolate synthase activity
SLCG_RS29595	COG0105	UTP biosynthetic process
SLCG_RS29600	COG1077	Cell shape determining protein MreB Mrl
SLCG_RS29615	COG0768	penicillin binding
SLCG_RS29620	COG0772	Belongs to the SEDS family
SLCG_RS29660	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SLCG_RS29665	COG2195	Cleaves the N-terminal amino acid of tripeptides
SLCG_RS29685	COG1530	ribonuclease E activity
SLCG_RS29715	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SLCG_RS29720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SLCG_RS29725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SLCG_RS29735	COG3540	Alkaline phosphatase
SLCG_RS29755	COG1442	glycosyl transferase family 8
SLCG_RS29755	COG1216	Glycosyl transferase, family 2
SLCG_RS29765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SLCG_RS29775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SLCG_RS29790	COG0501	Belongs to the peptidase M48B family
SLCG_RS29800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SLCG_RS29810	COG0799	negative regulation of ribosome biogenesis
SLCG_RS29815	COG0588	phosphoglycerate mutase activity
SLCG_RS29830	COG0477	Major facilitator Superfamily
SLCG_RS29850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLCG_RS29860	COG0495	leucyl-tRNA aminoacylation
SLCG_RS29870	COG1307	EDD domain protein, DegV family
SLCG_RS29875	COG1555	photosystem II stabilization
SLCG_RS29875	COG1596	polysaccharide export
SLCG_RS29880	COG0658	competence protein
SLCG_RS29880	COG2333	competence protein COMEC
SLCG_RS29885	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SLCG_RS29890	COG2353	YceI-like domain
SLCG_RS29910	COG0268	Binds directly to 16S ribosomal RNA
SLCG_RS29915	COG0481	GTPase activity
SLCG_RS29960	COG1420	regulation of RNA biosynthetic process
SLCG_RS29965	COG0484	heat shock protein binding
SLCG_RS29995	COG0793	Belongs to the peptidase S41A family
SLCG_RS29995	COG4946	Tricorn protease homolog
SLCG_RS30000	COG0537	adenosine 5'-monophosphoramidase activity
SLCG_RS30005	COG1234	tRNA 3'-trailer cleavage
SLCG_RS30010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLCG_RS30015	COG1414	Transcriptional regulator
SLCG_RS30020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLCG_RS30025	COG4948	Mandelate Racemase Muconate Lactonizing
SLCG_RS30040	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SLCG_RS30050	COG2315	Protein conserved in bacteria
SLCG_RS30075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SLCG_RS30095	COG2723	6-phospho-beta-galactosidase activity
SLCG_RS30115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLCG_RS30125	COG2409	Drug exporters of the RND superfamily
SLCG_RS30130	COG4585	Histidine kinase
SLCG_RS30135	COG2197	response regulator
SLCG_RS30145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLCG_RS30165	COG1595	DNA-templated transcription, initiation
SLCG_RS30210	COG1381	Involved in DNA repair and RecF pathway recombination
SLCG_RS30215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLCG_RS30225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLCG_RS30230	COG1121	(ABC) transporter
SLCG_RS30235	COG3443	Belongs to the bacterial solute-binding protein 9 family
SLCG_RS30235	COG0803	Belongs to the bacterial solute-binding protein 9 family
SLCG_RS30240	COG0423	glycine-tRNA ligase activity
SLCG_RS30245	COG1280	lysine exporter protein (LysE YggA)
SLCG_RS30250	COG0667	Aldo Keto reductase
SLCG_RS30275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLCG_RS30300	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SLCG_RS30305	COG1940	carbohydrate kinase activity
SLCG_RS30305	COG1846	Transcriptional regulator
SLCG_RS30310	COG0574	Belongs to the PEP-utilizing enzyme family
SLCG_RS30310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLCG_RS30330	COG0745	RESPONSE REGULATOR receiver
SLCG_RS30340	COG0659	secondary active sulfate transmembrane transporter activity
SLCG_RS30355	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS30360	COG1309	transcriptional regulator
SLCG_RS30370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLCG_RS30370	COG2146	nitrite reductase [NAD(P)H] activity
SLCG_RS30375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLCG_RS30395	COG1733	regulation of RNA biosynthetic process
SLCG_RS30425	COG2072	flavoprotein involved in K transport
SLCG_RS30440	COG0243	molybdopterin cofactor binding
SLCG_RS30450	COG2949	membrane
SLCG_RS30460	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SLCG_RS30470	COG0358	DNA primase activity
SLCG_RS30475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLCG_RS30490	COG1070	Carbohydrate kinase
SLCG_RS30535	COG2409	Drug exporters of the RND superfamily
SLCG_RS30540	COG2205	protein histidine kinase activity
SLCG_RS30545	COG0745	RESPONSE REGULATOR receiver
SLCG_RS30560	COG1116	anion transmembrane transporter activity
SLCG_RS30565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLCG_RS30575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS30610	COG1132	(ABC) transporter
SLCG_RS30615	COG4585	Histidine kinase
SLCG_RS30620	COG2197	response regulator
SLCG_RS30650	COG0515	serine threonine protein kinase
SLCG_RS30650	COG2815	serine threonine protein kinase
SLCG_RS30675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS30705	COG3629	intracellular signal transduction
SLCG_RS30705	COG3903	Transcriptional regulator
SLCG_RS30740	COG1077	Cell shape determining protein MreB Mrl
SLCG_RS30765	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SLCG_RS30765	COG0825	malonyl-CoA metabolic process
SLCG_RS30770	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS30780	COG2186	Transcriptional regulator
SLCG_RS30825	COG4981	capsule polysaccharide biosynthetic process
SLCG_RS30850	COG1414	Transcriptional regulator
SLCG_RS30855	COG3386	PFAM SMP-30 Gluconolaconase
SLCG_RS30885	COG1175	transmembrane transport
SLCG_RS30890	COG0395	ABC-type sugar transport system, permease component
SLCG_RS30895	COG3507	Belongs to the glycosyl hydrolase 43 family
SLCG_RS30960	COG3507	Belongs to the glycosyl hydrolase 43 family
SLCG_RS30965	COG3940	Belongs to the glycosyl hydrolase 43 family
SLCG_RS30980	COG4214	carbohydrate transport
SLCG_RS30985	COG1129	ABC transporter
SLCG_RS31005	COG4948	Mandelate Racemase Muconate Lactonizing
SLCG_RS31025	COG2130	NADP-dependent
SLCG_RS31090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLCG_RS31095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLCG_RS31100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLCG_RS31115	COG1741	Belongs to the pirin family
SLCG_RS31130	COG0789	Transcriptional regulator
SLCG_RS31135	COG0667	Aldo Keto reductase
SLCG_RS31150	COG1309	transcriptional regulator
SLCG_RS31155	COG0477	Major facilitator Superfamily
SLCG_RS31170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLCG_RS31175	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLCG_RS31220	COG1358	cellular component organization or biogenesis
SLCG_RS31230	COG0586	Pfam SNARE associated Golgi protein
SLCG_RS31270	COG0596	Alpha beta hydrolase
SLCG_RS31280	COG2318	DinB family
SLCG_RS31290	COG2814	Major facilitator Superfamily
SLCG_RS31315	COG2259	Doxx family
SLCG_RS31390	COG4122	O-methyltransferase activity
SLCG_RS31405	COG2124	cytochrome p450
SLCG_RS31410	COG0183	Belongs to the thiolase family
SLCG_RS31435	COG0640	Transcriptional regulator
SLCG_RS31450	COG3619	membrane
SLCG_RS31465	COG3845	ABC transporter
SLCG_RS31505	COG1309	transcriptional regulator
SLCG_RS31510	COG0438	transferase activity, transferring glycosyl groups
SLCG_RS31545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS31555	COG0860	N-Acetylmuramoyl-L-alanine amidase
SLCG_RS31575	COG2197	response regulator
SLCG_RS31580	COG4585	Histidine kinase
SLCG_RS31585	COG2030	dehydratase
SLCG_RS31595	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS31605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SLCG_RS31620	COG0800	Aldolase
SLCG_RS31625	COG3022	response to hydroperoxide
SLCG_RS31630	COG0557	exoribonuclease II activity
SLCG_RS31730	COG1175	transmembrane transport
SLCG_RS31735	COG0395	ABC-type sugar transport system, permease component
SLCG_RS31755	COG2259	Doxx family
SLCG_RS31775	COG3540	Alkaline phosphatase
SLCG_RS31785	COG2814	Major facilitator Superfamily
SLCG_RS31790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLCG_RS31805	COG0584	glycerophosphoryl diester phosphodiesterase
SLCG_RS31820	COG0672	)-iron permease
SLCG_RS31825	COG2837	iron assimilation
SLCG_RS31835	COG1120	ATPase activity
SLCG_RS31845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS31890	COG1994	Peptidase M50
SLCG_RS31915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SLCG_RS31920	COG0477	Major facilitator Superfamily
SLCG_RS31925	COG1309	transcriptional regulator
SLCG_RS31955	COG0574	Belongs to the PEP-utilizing enzyme family
SLCG_RS31955	COG3848	Pyruvate phosphate dikinase
SLCG_RS31960	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SLCG_RS31960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLCG_RS31985	COG0174	glutamine synthetase
SLCG_RS32010	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SLCG_RS32020	COG1609	Transcriptional regulator
SLCG_RS32030	COG1175	transmembrane transport
SLCG_RS32035	COG3833	ABC-type maltose transport systems, permease component
SLCG_RS32040	COG0366	Alpha amylase catalytic
SLCG_RS32075	COG1309	transcriptional regulator
SLCG_RS32100	COG2197	response regulator
SLCG_RS32105	COG4585	Histidine kinase
SLCG_RS32115	COG0745	RESPONSE REGULATOR receiver
SLCG_RS32165	COG0501	Belongs to the peptidase M48B family
SLCG_RS32175	COG0174	glutamine synthetase
SLCG_RS32195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SLCG_RS32200	COG0321	lipoyl(octanoyl) transferase activity
SLCG_RS32215	COG1090	epimerase
SLCG_RS32255	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLCG_RS32270	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLCG_RS32275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SLCG_RS32285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SLCG_RS32315	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SLCG_RS32330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLCG_RS32370	COG4585	Histidine kinase
SLCG_RS32375	COG2197	response regulator
SLCG_RS32380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SLCG_RS32385	COG0515	serine threonine protein kinase
SLCG_RS32385	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLCG_RS32390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SLCG_RS32415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLCG_RS32425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SLCG_RS32430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SLCG_RS32440	COG1376	ErfK ybiS ycfS ynhG family protein
SLCG_RS32450	COG1845	cytochrome c oxidase, subunit III
SLCG_RS32455	COG2010	Cytochrome c
SLCG_RS32460	COG0723	plastoquinol--plastocyanin reductase activity
SLCG_RS32465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLCG_RS32470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SLCG_RS32475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLCG_RS32480	COG1929	Belongs to the glycerate kinase type-1 family
SLCG_RS32490	COG0745	RESPONSE REGULATOR receiver
SLCG_RS32495	COG5002	protein histidine kinase activity
SLCG_RS32555	COG1022	Amp-dependent synthetase and ligase
SLCG_RS32570	COG0003	Pfam Anion-transporting ATPase
SLCG_RS32580	COG1940	carbohydrate kinase activity
SLCG_RS32605	COG4585	Histidine kinase
SLCG_RS32610	COG2197	response regulator
SLCG_RS32615	COG0205	6-phosphofructokinase activity
SLCG_RS32630	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SLCG_RS32635	COG0243	molybdopterin cofactor binding
SLCG_RS32640	COG2193	ferroxidase activity
SLCG_RS32645	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLCG_RS32650	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SLCG_RS32655	COG2815	serine threonine protein kinase
SLCG_RS32655	COG0515	serine threonine protein kinase
SLCG_RS32660	COG2022	thiamine diphosphate biosynthetic process
SLCG_RS32670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS32670	COG2022	thiamine diphosphate biosynthetic process
SLCG_RS32690	COG0352	thiamine-phosphate diphosphorylase activity
SLCG_RS32710	COG1309	transcriptional regulator
SLCG_RS32720	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SLCG_RS32730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLCG_RS32750	COG0714	Associated with various cellular activities
SLCG_RS32760	COG0275	rRNA processing
SLCG_RS32770	COG0768	penicillin binding
SLCG_RS32775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SLCG_RS32785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLCG_RS32790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLCG_RS32800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SLCG_RS32805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SLCG_RS32810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SLCG_RS32815	COG1496	oxidoreductase activity
SLCG_RS32825	COG1799	cell septum assembly
SLCG_RS32835	COG3599	regulation of cell shape
SLCG_RS32840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SLCG_RS32855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SLCG_RS32910	COG0587	DNA-directed DNA polymerase activity
SLCG_RS32915	COG1432	Conserved Protein
SLCG_RS32955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SLCG_RS32960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLCG_RS32965	COG0131	Imidazoleglycerol-phosphate dehydratase
SLCG_RS32970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SLCG_RS32975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SLCG_RS32980	COG0251	oxidation-reduction process
SLCG_RS32985	COG0107	imidazoleglycerol-phosphate synthase activity
SLCG_RS33005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SLCG_RS33010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SLCG_RS33030	COG0134	indole-3-glycerol-phosphate synthase activity
SLCG_RS33035	COG0133	tryptophan synthase activity
SLCG_RS33040	COG0159	tryptophan synthase activity
SLCG_RS33050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SLCG_RS33055	COG2301	Belongs to the HpcH HpaI aldolase family
SLCG_RS33060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLCG_RS33090	COG0070	glutamate synthase
SLCG_RS33090	COG0069	glutamate synthase activity
SLCG_RS33090	COG0067	glutamate synthase
SLCG_RS33100	COG2304	oxidoreductase activity
SLCG_RS33105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLCG_RS33110	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS33115	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS33120	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS33125	COG1309	transcriptional regulator
SLCG_RS33130	COG0183	Belongs to the thiolase family
SLCG_RS33150	COG1024	Enoyl-CoA hydratase
SLCG_RS33180	COG1605	Chorismate mutase
SLCG_RS33180	COG0287	Prephenate dehydrogenase
SLCG_RS33205	COG0737	Belongs to the 5'-nucleotidase family
SLCG_RS33265	COG2050	protein possibly involved in aromatic compounds catabolism
SLCG_RS33305	COG1643	Atp-dependent helicase
SLCG_RS33310	COG2226	methyltransferase
SLCG_RS33325	COG0237	dephospho-CoA kinase activity
SLCG_RS33365	COG1802	Transcriptional regulator
SLCG_RS33370	COG1953	Uracil, thiamine, allantoin
SLCG_RS33410	COG0402	S-adenosylhomocysteine deaminase activity
SLCG_RS33425	COG1132	(ABC) transporter
SLCG_RS33465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLCG_RS33470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS33500	COG0598	Magnesium transport protein CorA
SLCG_RS33505	COG2226	methyltransferase
SLCG_RS33510	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SLCG_RS33510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SLCG_RS33515	COG2313	pseudouridylate synthase activity
SLCG_RS33525	COG1063	alcohol dehydrogenase
SLCG_RS33530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLCG_RS33535	COG0584	glycerophosphoryl diester phosphodiesterase
SLCG_RS33545	COG0556	nucleotide-excision repair
SLCG_RS33570	COG0387	Pfam Sodium calcium exchanger
SLCG_RS33575	COG0477	Major facilitator Superfamily
SLCG_RS33580	COG1619	proteins homologs of microcin C7 resistance protein MccF
SLCG_RS33585	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SLCG_RS33595	COG0765	amino acid transport
SLCG_RS33600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLCG_RS33615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLCG_RS33635	COG2197	response regulator
SLCG_RS33645	COG4585	Histidine kinase
SLCG_RS33650	COG2197	response regulator
SLCG_RS33655	COG0322	excinuclease ABC activity
SLCG_RS33660	COG1660	Displays ATPase and GTPase activities
SLCG_RS33665	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLCG_RS33670	COG1481	regulation of sporulation
SLCG_RS33680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SLCG_RS33685	COG0126	phosphoglycerate kinase activity
SLCG_RS33690	COG0149	triose-phosphate isomerase activity
SLCG_RS33695	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SLCG_RS33710	COG0166	Belongs to the GPI family
SLCG_RS33715	COG0363	glucosamine-6-phosphate deaminase activity
SLCG_RS33730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLCG_RS33745	COG0109	protoheme IX farnesyltransferase activity
SLCG_RS33770	COG3629	intracellular signal transduction
SLCG_RS33770	COG3903	Transcriptional regulator
SLCG_RS33785	COG2746	aminoglycoside 3-N-acetyltransferase activity
SLCG_RS33800	COG0719	Fe-S assembly protein
SLCG_RS33810	COG0396	ATPase activity
SLCG_RS33815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLCG_RS33820	COG0822	iron-sulfur transferase activity
SLCG_RS33825	COG2151	metal-sulfur cluster biosynthetic enzyme
SLCG_RS33835	COG2076	Multidrug Resistance protein
SLCG_RS33840	COG3226	Transcriptional regulator
SLCG_RS33845	COG2171	N-acyltransferase activity
SLCG_RS33855	COG1595	DNA-templated transcription, initiation
SLCG_RS33865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLCG_RS33885	COG1959	2 iron, 2 sulfur cluster binding
SLCG_RS33885	COG1295	ribonuclease BN
SLCG_RS33940	COG1802	Transcriptional regulator
SLCG_RS33960	COG1175	transmembrane transport
SLCG_RS33965	COG0395	ABC-type sugar transport system, permease component
SLCG_RS33990	COG1063	alcohol dehydrogenase
SLCG_RS33995	COG0395	ABC-type sugar transport system, permease component
SLCG_RS34010	COG1349	DNA-binding transcription factor activity
SLCG_RS34015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLCG_RS34020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLCG_RS34045	COG1802	Transcriptional regulator
SLCG_RS34060	COG1175	transmembrane transport
SLCG_RS34065	COG0395	ABC-type sugar transport system, permease component
SLCG_RS34070	COG3866	Pectate lyase
SLCG_RS34085	COG3507	Belongs to the glycosyl hydrolase 43 family
SLCG_RS34090	COG4677	pectinesterase activity
SLCG_RS34100	COG2755	lipolytic protein G-D-S-L family
SLCG_RS34110	COG4677	pectinesterase activity
SLCG_RS34115	COG4677	pectinesterase activity
SLCG_RS34130	COG4733	cellulase activity
SLCG_RS34160	COG1595	DNA-templated transcription, initiation
SLCG_RS34165	COG2252	PERMEase
SLCG_RS34175	COG2197	response regulator
SLCG_RS34180	COG4585	Histidine kinase
SLCG_RS34190	COG1414	Transcriptional regulator
SLCG_RS34220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLCG_RS34225	COG1595	DNA-templated transcription, initiation
SLCG_RS34235	COG5285	phytanoyl-CoA dioxygenase
SLCG_RS34240	COG1917	Cupin 2, conserved barrel domain protein
SLCG_RS34245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLCG_RS34250	COG0456	acetyltransferase
SLCG_RS34255	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SLCG_RS34265	COG0765	amino acid transport
SLCG_RS34275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLCG_RS34335	COG1797	cobyrinic acid a,c-diamide synthase activity
SLCG_RS34355	COG1492	cobalamin metabolic process
SLCG_RS34360	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SLCG_RS34380	COG0235	Class ii aldolase
SLCG_RS34400	COG0488	(ABC) transporter
SLCG_RS34410	COG1024	Enoyl-CoA hydratase
SLCG_RS34450	COG3387	PFAM Glycoside hydrolase 15-related
SLCG_RS34465	COG2176	DNA-directed DNA polymerase activity
SLCG_RS34475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLCG_RS34495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLCG_RS34500	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SLCG_RS34520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SLCG_RS34530	COG0312	modulator of DNA gyrase
SLCG_RS34535	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS34550	COG2186	Transcriptional regulator
SLCG_RS34565	COG0588	phosphoglycerate mutase activity
SLCG_RS34570	COG3830	Belongs to the UPF0237 family
SLCG_RS34570	COG0560	Phosphoserine phosphatase
SLCG_RS34580	COG0842	Transport permease protein
SLCG_RS34580	COG1131	(ABC) transporter
SLCG_RS34580	COG1716	ATPase activity
SLCG_RS34590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SLCG_RS34595	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS34605	COG2197	response regulator
SLCG_RS34625	COG1119	ATPase activity
SLCG_RS34645	COG1881	PFAM PEBP family protein
SLCG_RS34655	COG2094	Belongs to the DNA glycosylase MPG family
SLCG_RS34690	COG0647	UMP catabolic process
SLCG_RS34700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS34705	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS34710	COG1120	ATPase activity
SLCG_RS34730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SLCG_RS34735	COG0497	DNA recombination
SLCG_RS34740	COG0438	transferase activity, transferring glycosyl groups
SLCG_RS34755	COG3387	PFAM Glycoside hydrolase 15-related
SLCG_RS34760	COG0504	CTP synthase activity
SLCG_RS34765	COG0494	nUDIX hydrolase
SLCG_RS34775	COG0686	Belongs to the AlaDH PNT family
SLCG_RS34790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SLCG_RS34795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SLCG_RS34800	COG1187	pseudouridine synthase activity
SLCG_RS34815	COG0477	Major facilitator Superfamily
SLCG_RS34825	COG1397	ADP-ribosylglycohydrolase
SLCG_RS34855	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SLCG_RS34865	COG1160	GTP binding
SLCG_RS34880	COG1652	LysM domain
SLCG_RS34890	COG1129	ABC transporter
SLCG_RS34930	COG0671	phosphoesterase, PA-phosphatase related
SLCG_RS34940	COG0477	Major facilitator Superfamily
SLCG_RS34945	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS34950	COG1799	cell septum assembly
SLCG_RS34960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLCG_RS34965	COG0765	amino acid transport
SLCG_RS34975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS34990	COG0330	HflC and HflK could
SLCG_RS35005	COG0587	DNA-directed DNA polymerase activity
SLCG_RS35010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SLCG_RS35060	COG1725	Transcriptional regulator
SLCG_RS35085	COG0726	polysaccharide deacetylase
SLCG_RS35085	COG1649	PFAM Uncharacterised BCR, COG1649
SLCG_RS35090	COG1216	Glycosyl transferase, family 2
SLCG_RS35115	COG2755	lipolytic protein G-D-S-L family
SLCG_RS35120	COG2815	serine threonine protein kinase
SLCG_RS35120	COG0515	serine threonine protein kinase
SLCG_RS35140	COG1595	DNA-templated transcription, initiation
SLCG_RS35175	COG2188	Transcriptional regulator
SLCG_RS35180	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SLCG_RS35190	COG1309	transcriptional regulator
SLCG_RS35205	COG0243	molybdopterin cofactor binding
SLCG_RS35210	COG2851	Citrate transporter
SLCG_RS35240	COG0477	Major facilitator Superfamily
SLCG_RS35250	COG0640	Transcriptional regulator
SLCG_RS35260	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS35315	COG3876	Protein conserved in bacteria
SLCG_RS35325	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS35355	COG2149	membrane
SLCG_RS35360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLCG_RS35405	COG1063	alcohol dehydrogenase
SLCG_RS35410	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS35420	COG3265	gluconokinase activity
SLCG_RS35425	COG2186	Transcriptional regulator
SLCG_RS35430	COG3012	SEC-C Motif Domain Protein
SLCG_RS35440	COG0308	aminopeptidase N
SLCG_RS35455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLCG_RS35485	COG0667	Aldo Keto reductase
SLCG_RS35490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS35500	COG0598	Magnesium transport protein CorA
SLCG_RS35505	COG0588	phosphoglycerate mutase activity
SLCG_RS35520	COG0215	cysteine-tRNA ligase activity
SLCG_RS35530	COG1404	Belongs to the peptidase S8 family
SLCG_RS35545	COG2186	Transcriptional regulator
SLCG_RS35555	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SLCG_RS35555	COG0235	Class ii aldolase
SLCG_RS35560	COG0235	Class ii aldolase
SLCG_RS35565	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SLCG_RS35570	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SLCG_RS35580	COG1129	ABC transporter
SLCG_RS35590	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
SLCG_RS35595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SLCG_RS35600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLCG_RS35605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLCG_RS35610	COG1414	Transcriptional regulator
SLCG_RS35615	COG0646	methionine synthase
SLCG_RS35615	COG1410	methionine synthase
SLCG_RS35620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLCG_RS35625	COG4166	transmembrane transport
SLCG_RS35635	COG2197	response regulator
SLCG_RS35645	COG1994	Peptidase M50
SLCG_RS35645	COG0517	IMP dehydrogenase activity
SLCG_RS35670	COG1222	aaa ATPase
SLCG_RS35675	COG4122	O-methyltransferase activity
SLCG_RS35690	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLCG_RS35695	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLCG_RS35700	COG1609	Transcriptional regulator
SLCG_RS35710	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLCG_RS35715	COG0545	Peptidyl-prolyl cis-trans isomerase
SLCG_RS35745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLCG_RS35750	COG0805	protein transport
SLCG_RS35755	COG2205	protein histidine kinase activity
SLCG_RS35765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SLCG_RS35775	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLCG_RS35780	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SLCG_RS35850	COG2124	cytochrome p450
SLCG_RS35890	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SLCG_RS35920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLCG_RS35930	COG4176	ABC-type proline glycine betaine transport system permease component
SLCG_RS35955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SLCG_RS35965	COG0174	glutamine synthetase
SLCG_RS35970	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS36020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SLCG_RS36025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SLCG_RS36030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SLCG_RS36035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SLCG_RS36040	COG5002	protein histidine kinase activity
SLCG_RS36045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SLCG_RS36050	COG0072	phenylalanine-tRNA ligase activity
SLCG_RS36050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLCG_RS36080	COG1649	PFAM Uncharacterised BCR, COG1649
SLCG_RS36090	COG0697	spore germination
SLCG_RS36120	COG3708	Transcriptional regulator
SLCG_RS36120	COG2207	Transcriptional regulator
SLCG_RS36145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLCG_RS36150	COG1120	ATPase activity
SLCG_RS36155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SLCG_RS36160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SLCG_RS36165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SLCG_RS36170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLCG_RS36175	COG1438	arginine binding
SLCG_RS36210	COG0165	Argininosuccinate lyase
SLCG_RS36225	COG0477	Major facilitator Superfamily
SLCG_RS36235	COG0714	Associated with various cellular activities
SLCG_RS36245	COG2304	oxidoreductase activity
SLCG_RS36250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLCG_RS36255	COG0745	RESPONSE REGULATOR receiver
SLCG_RS36260	COG2205	protein histidine kinase activity
SLCG_RS36265	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS36265	COG0204	Acyl-transferase
SLCG_RS36270	COG0584	glycerophosphoryl diester phosphodiesterase
SLCG_RS36295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLCG_RS36300	COG2011	ABC-type metal ion transport system permease component
SLCG_RS36305	COG1464	Belongs to the NlpA lipoprotein family
SLCG_RS36320	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLCG_RS36325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SLCG_RS36325	COG1648	precorrin-2 dehydrogenase activity
SLCG_RS36435	COG1653	transport
SLCG_RS36440	COG1175	transmembrane transport
SLCG_RS36445	COG0395	ABC-type sugar transport system, permease component
SLCG_RS36475	COG5002	protein histidine kinase activity
SLCG_RS36475	COG2176	DNA-directed DNA polymerase activity
SLCG_RS36490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLCG_RS36510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SLCG_RS36515	COG1560	Kdo2-lipid A biosynthetic process
SLCG_RS36520	COG0438	transferase activity, transferring glycosyl groups
SLCG_RS36530	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SLCG_RS36535	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SLCG_RS36540	COG0217	transcriptional regulatory protein
SLCG_RS36545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SLCG_RS36550	COG0632	four-way junction helicase activity
SLCG_RS36555	COG2255	four-way junction helicase activity
SLCG_RS36565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLCG_RS36570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLCG_RS36575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SLCG_RS36585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLCG_RS36615	COG2197	response regulator
SLCG_RS36620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLCG_RS36625	COG0318	PFAM AMP-dependent synthetase and ligase
SLCG_RS36640	COG1472	Belongs to the glycosyl hydrolase 3 family
SLCG_RS36645	COG5297	Belongs to the glycosyl hydrolase family 6
SLCG_RS36660	COG3960	tartronate-semialdehyde synthase activity
SLCG_RS36665	COG2084	Dehydrogenase
SLCG_RS36670	COG3622	Belongs to the hyi family
SLCG_RS36690	COG2351	hydroxyisourate hydrolase activity
SLCG_RS36705	COG2233	PERMEase
SLCG_RS36725	COG1733	regulation of RNA biosynthetic process
SLCG_RS36740	COG0436	Aminotransferase
SLCG_RS36745	COG1733	regulation of RNA biosynthetic process
SLCG_RS36760	COG4264	IucA IucC family
SLCG_RS36785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLCG_RS36840	COG1132	(ABC) transporter
SLCG_RS36845	COG1132	(ABC) transporter
SLCG_RS36870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SLCG_RS36875	COG0746	molybdenum cofactor guanylyltransferase activity
SLCG_RS36890	COG1414	Transcriptional regulator
SLCG_RS36895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLCG_RS36900	COG4266	Belongs to the allantoicase family
SLCG_RS36905	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS36930	COG2197	response regulator
SLCG_RS36940	COG0673	inositol 2-dehydrogenase activity
SLCG_RS36945	COG2188	Transcriptional regulator
SLCG_RS36950	COG1940	carbohydrate kinase activity
SLCG_RS36960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLCG_RS36970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS36975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SLCG_RS36995	COG2936	dipeptidyl-peptidase activity
SLCG_RS37005	COG0405	Gamma-glutamyltransferase
SLCG_RS37015	COG0702	epimerase
SLCG_RS37030	COG0583	DNA-binding transcription factor activity
SLCG_RS37035	COG0542	response to heat
SLCG_RS37060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLCG_RS37075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLCG_RS37085	COG1953	Uracil, thiamine, allantoin
SLCG_RS37100	COG3851	Histidine kinase
SLCG_RS37105	COG2197	response regulator
SLCG_RS37110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLCG_RS37120	COG0483	inositol monophosphate 1-phosphatase activity
SLCG_RS37130	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SLCG_RS37155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLCG_RS37170	COG0529	Catalyzes the synthesis of activated sulfate
SLCG_RS37175	COG2814	Major facilitator Superfamily
SLCG_RS37180	COG4977	sequence-specific DNA binding
SLCG_RS37195	COG2197	response regulator
SLCG_RS37210	COG4171	peptide transport system, permease
SLCG_RS37215	COG0601	transmembrane transport
SLCG_RS37220	COG0747	negative chemotaxis
SLCG_RS37235	COG0640	Transcriptional regulator
SLCG_RS37255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SLCG_RS37270	COG1929	Belongs to the glycerate kinase type-1 family
SLCG_RS37295	COG0559	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS37315	COG0688	phosphatidylethanolamine metabolic process
SLCG_RS37320	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS37335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS37335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLCG_RS37340	COG0604	alcohol dehydrogenase
SLCG_RS37350	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS37370	COG0596	Alpha beta hydrolase
SLCG_RS37390	COG2208	phosphoserine phosphatase activity
SLCG_RS37390	COG1366	Belongs to the anti-sigma-factor antagonist family
SLCG_RS37390	COG2172	sigma factor antagonist activity
SLCG_RS37395	COG2226	methyltransferase
SLCG_RS37455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLCG_RS37460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLCG_RS37495	COG2814	Major facilitator Superfamily
SLCG_RS37505	COG2362	D-Aminopeptidase
SLCG_RS37510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLCG_RS37515	COG1506	peptidase
SLCG_RS37515	COG0823	Involved in the tonB-independent uptake of proteins
SLCG_RS37515	COG4946	Tricorn protease homolog
SLCG_RS37520	COG1619	proteins homologs of microcin C7 resistance protein MccF
SLCG_RS37550	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS37555	COG4948	Mandelate Racemase Muconate Lactonizing
SLCG_RS37560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS37575	COG1793	dna ligase
SLCG_RS37575	COG3285	dna ligase
SLCG_RS37640	COG1597	lipid kinase activity
SLCG_RS37645	COG0488	(ABC) transporter
SLCG_RS37665	COG0693	protein deglycase activity
SLCG_RS37675	COG0517	IMP dehydrogenase activity
SLCG_RS37675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SLCG_RS37695	COG0028	Belongs to the TPP enzyme family
SLCG_RS37725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SLCG_RS37765	COG0443	Heat shock 70 kDa protein
SLCG_RS37795	COG2154	pterin-4-alpha-carbinolamine dehydratase
SLCG_RS37800	COG2226	methyltransferase
SLCG_RS37815	COG2378	regulation of single-species biofilm formation
SLCG_RS37820	COG3401	FG-GAP repeat protein
SLCG_RS37830	COG5297	Belongs to the glycosyl hydrolase family 6
SLCG_RS37830	COG4733	cellulase activity
SLCG_RS37835	COG5297	Belongs to the glycosyl hydrolase family 6
SLCG_RS37890	COG1335	isochorismatase
SLCG_RS37900	COG0583	DNA-binding transcription factor activity
SLCG_RS37905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SLCG_RS37915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLCG_RS37920	COG3383	formate dehydrogenase (NAD+) activity
SLCG_RS37925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SLCG_RS37940	COG2409	Drug exporters of the RND superfamily
SLCG_RS37950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLCG_RS37965	COG1940	carbohydrate kinase activity
SLCG_RS37970	COG1129	ABC transporter
SLCG_RS37975	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS37985	COG0673	inositol 2-dehydrogenase activity
SLCG_RS37995	COG3507	Belongs to the glycosyl hydrolase 43 family
SLCG_RS38010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SLCG_RS38050	COG2223	nitrite transmembrane transporter activity
SLCG_RS38060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLCG_RS38070	COG0045	succinate-CoA ligase (ADP-forming) activity
SLCG_RS38080	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS38095	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLCG_RS38100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS38105	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS38110	COG1120	ATPase activity
SLCG_RS38120	COG1132	(ABC) transporter
SLCG_RS38130	COG1132	(ABC) transporter
SLCG_RS38155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLCG_RS38160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLCG_RS38190	COG0747	negative chemotaxis
SLCG_RS38225	COG0297	glycogen (starch) synthase activity
SLCG_RS38245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLCG_RS38250	COG2423	ornithine cyclodeaminase activity
SLCG_RS38280	COG3467	pyridoxamine 5'-phosphate
SLCG_RS38285	COG0346	lactoylglutathione lyase activity
SLCG_RS38295	COG0477	Major facilitator Superfamily
SLCG_RS38305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SLCG_RS38310	COG1082	Xylose isomerase domain protein TIM barrel
SLCG_RS38310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SLCG_RS38320	COG0588	phosphoglycerate mutase activity
SLCG_RS38325	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SLCG_RS38330	COG0166	Belongs to the GPI family
SLCG_RS38345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLCG_RS38370	COG2409	Drug exporters of the RND superfamily
SLCG_RS38380	COG2197	response regulator
SLCG_RS38385	COG3850	Histidine kinase
SLCG_RS38400	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS38425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLCG_RS38430	COG3250	beta-galactosidase activity
SLCG_RS38440	COG1175	transmembrane transport
SLCG_RS38460	COG1486	melibiose metabolic process
SLCG_RS38485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLCG_RS38515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLCG_RS38525	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLCG_RS38530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLCG_RS38535	COG3938	Belongs to the proline racemase family
SLCG_RS38545	COG1116	anion transmembrane transporter activity
SLCG_RS38550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLCG_RS38555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLCG_RS38565	COG1414	Transcriptional regulator
SLCG_RS38585	COG2197	response regulator
SLCG_RS38635	COG1175	transmembrane transport
SLCG_RS38640	COG0395	ABC-type sugar transport system, permease component
SLCG_RS38645	COG1940	carbohydrate kinase activity
SLCG_RS38665	COG0477	Major facilitator Superfamily
SLCG_RS38670	COG3511	phospholipase C
SLCG_RS38705	COG1672	PFAM Archaeal ATPase
SLCG_RS38705	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLCG_RS38715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS38720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLCG_RS38725	COG3485	protocatechuate 3,4-dioxygenase
SLCG_RS38730	COG3485	protocatechuate 3,4-dioxygenase
SLCG_RS38735	COG0183	Belongs to the thiolase family
SLCG_RS38765	COG1793	dna ligase
SLCG_RS38815	COG1834	amidinotransferase
SLCG_RS38820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLCG_RS38825	COG0488	(ABC) transporter
SLCG_RS38850	COG1515	deoxyribonuclease V activity
SLCG_RS38855	COG3268	Saccharopine dehydrogenase
SLCG_RS38865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLCG_RS38870	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS38875	COG0183	Belongs to the thiolase family
SLCG_RS38880	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLCG_RS38880	COG1024	Enoyl-CoA hydratase
SLCG_RS38890	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS38900	COG1113	amino acid transport
SLCG_RS38910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLCG_RS38920	COG2936	dipeptidyl-peptidase activity
SLCG_RS38930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SLCG_RS38945	COG0488	(ABC) transporter
SLCG_RS38955	COG2183	response to ionizing radiation
SLCG_RS38965	COG4977	sequence-specific DNA binding
SLCG_RS38975	COG1024	Enoyl-CoA hydratase
SLCG_RS38990	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLCG_RS39035	COG1134	teichoic acid transport
SLCG_RS39040	COG1562	ergosterol biosynthetic process
SLCG_RS39050	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLCG_RS39060	COG1657	PFAM Prenyltransferase squalene oxidase
SLCG_RS39075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLCG_RS39080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLCG_RS39130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SLCG_RS39175	COG1063	alcohol dehydrogenase
SLCG_RS39180	COG0156	8-amino-7-oxononanoate synthase activity
SLCG_RS39185	COG0583	DNA-binding transcription factor activity
SLCG_RS39235	COG0174	glutamine synthetase
SLCG_RS39250	COG2197	response regulator
SLCG_RS39260	COG1136	(ABC) transporter
SLCG_RS39275	COG0006	proline dipeptidase activity
SLCG_RS39280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SLCG_RS39285	COG0022	dehydrogenase e1 component
SLCG_RS39290	COG0402	S-adenosylhomocysteine deaminase activity
SLCG_RS39295	COG1917	Cupin 2, conserved barrel domain protein
SLCG_RS39300	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS39325	COG0183	Belongs to the thiolase family
SLCG_RS39380	COG1132	(ABC) transporter
SLCG_RS39400	COG0494	nUDIX hydrolase
SLCG_RS39410	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SLCG_RS39415	COG2188	Transcriptional regulator
SLCG_RS39420	COG3962	Belongs to the TPP enzyme family
SLCG_RS39450	COG0673	inositol 2-dehydrogenase activity
SLCG_RS39455	COG0673	inositol 2-dehydrogenase activity
SLCG_RS39465	COG0673	inositol 2-dehydrogenase activity
SLCG_RS39470	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS39480	COG1609	Transcriptional regulator
SLCG_RS39490	COG1609	Transcriptional regulator
SLCG_RS39500	COG0477	Major facilitator Superfamily
SLCG_RS39505	COG1063	alcohol dehydrogenase
SLCG_RS39515	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLCG_RS39520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SLCG_RS39540	COG0477	Major facilitator Superfamily
SLCG_RS39570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS39580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLCG_RS39600	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLCG_RS39605	COG1007	ATP synthesis coupled electron transport
SLCG_RS39620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS39625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS39635	COG2197	response regulator
SLCG_RS39660	COG2124	cytochrome p450
SLCG_RS39675	COG2838	Isocitrate dehydrogenase
SLCG_RS39680	COG0668	transmembrane transport
SLCG_RS39695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLCG_RS39710	COG1024	Enoyl-CoA hydratase
SLCG_RS39720	COG1132	(ABC) transporter
SLCG_RS39755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SLCG_RS39790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SLCG_RS39810	COG0297	glycogen (starch) synthase activity
SLCG_RS39815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SLCG_RS39835	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS39890	COG2186	Transcriptional regulator
SLCG_RS39895	COG1879	ABC-type sugar transport system periplasmic component
SLCG_RS39900	COG1129	ABC transporter
SLCG_RS39905	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS39915	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS39930	COG3618	amidohydrolase
SLCG_RS39950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLCG_RS39985	COG2945	thiolester hydrolase activity
SLCG_RS39985	COG0596	Alpha beta hydrolase
SLCG_RS39990	COG0531	amino acid
SLCG_RS40005	COG0726	polysaccharide deacetylase
SLCG_RS40050	COG0583	DNA-binding transcription factor activity
SLCG_RS40060	COG1053	succinate dehydrogenase
SLCG_RS40065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SLCG_RS40095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLCG_RS40105	COG0523	cobalamin synthesis protein
SLCG_RS40130	COG1733	regulation of RNA biosynthetic process
SLCG_RS40140	COG3360	Dodecin
SLCG_RS40145	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SLCG_RS40150	COG0121	glutamine amidotransferase
SLCG_RS40155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLCG_RS40175	COG2268	Band 7 protein
SLCG_RS40195	COG0596	Alpha beta hydrolase
SLCG_RS40200	COG1414	Transcriptional regulator
SLCG_RS40205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLCG_RS40260	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS40310	COG2197	response regulator
SLCG_RS40315	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS40320	COG1414	Transcriptional regulator
SLCG_RS40325	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS40365	COG3409	Peptidoglycan-binding domain 1 protein
SLCG_RS40395	COG1408	metallophosphoesterase
SLCG_RS40410	COG4585	Histidine kinase
SLCG_RS40415	COG2197	response regulator
SLCG_RS40420	COG1802	Transcriptional regulator
SLCG_RS40455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SLCG_RS40485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLCG_RS40495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLCG_RS40500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SLCG_RS40515	COG3250	beta-galactosidase activity
SLCG_RS40530	COG0477	Major facilitator Superfamily
SLCG_RS40540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLCG_RS40545	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS40555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SLCG_RS40565	COG0583	DNA-binding transcription factor activity
SLCG_RS40570	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SLCG_RS40585	COG0148	phosphopyruvate hydratase activity
SLCG_RS40595	COG1609	Transcriptional regulator
SLCG_RS40600	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLCG_RS40605	COG2271	Major facilitator Superfamily
SLCG_RS40610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLCG_RS40645	COG0726	polysaccharide deacetylase
SLCG_RS40650	COG4249	Peptidase C14 caspase catalytic subunit p20
SLCG_RS40650	COG2319	Wd-40 repeat
SLCG_RS40655	COG1404	Belongs to the peptidase S8 family
SLCG_RS40665	COG2197	response regulator
SLCG_RS40685	COG0477	Major facilitator Superfamily
SLCG_RS40690	COG0300	oxidoreductase activity
SLCG_RS40745	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS40750	COG1278	Cold shock
SLCG_RS40755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLCG_RS40765	COG1902	pentaerythritol trinitrate reductase activity
SLCG_RS40775	COG2255	four-way junction helicase activity
SLCG_RS40805	COG1959	2 iron, 2 sulfur cluster binding
SLCG_RS40810	COG1511	domain protein
SLCG_RS40845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLCG_RS40855	COG1595	DNA-templated transcription, initiation
SLCG_RS40885	COG2409	Drug exporters of the RND superfamily
SLCG_RS40900	COG4585	Histidine kinase
SLCG_RS40905	COG2197	response regulator
SLCG_RS40915	COG3594	Acyltransferase
SLCG_RS40930	COG1609	Transcriptional regulator
SLCG_RS40940	COG1175	transmembrane transport
SLCG_RS40945	COG0395	ABC-type sugar transport system, permease component
SLCG_RS40960	COG4221	oxidoreductase activity
SLCG_RS40970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLCG_RS41010	COG0583	DNA-binding transcription factor activity
SLCG_RS41030	COG1609	Transcriptional regulator
SLCG_RS41040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLCG_RS41060	COG0242	peptide deformylase activity
SLCG_RS41090	COG1131	(ABC) transporter
SLCG_RS41115	COG2409	Drug exporters of the RND superfamily
SLCG_RS41120	COG4585	Histidine kinase
SLCG_RS41125	COG2197	response regulator
SLCG_RS41140	COG0436	Aminotransferase
SLCG_RS41145	COG1819	glycosyl
SLCG_RS41155	COG1609	Transcriptional regulator
SLCG_RS41165	COG1175	transmembrane transport
SLCG_RS41175	COG3250	beta-galactosidase activity
SLCG_RS41225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SLCG_RS41235	COG0601	transmembrane transport
SLCG_RS41240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLCG_RS41245	COG0444	Belongs to the ABC transporter superfamily
SLCG_RS41250	COG1124	(ABC) transporter
SLCG_RS41255	COG3396	Phenylacetate-CoA oxygenase
SLCG_RS41260	COG3460	Phenylacetate-CoA oxygenase
SLCG_RS41265	COG3396	Phenylacetate-CoA oxygenase
SLCG_RS41270	COG2151	metal-sulfur cluster biosynthetic enzyme
SLCG_RS41275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLCG_RS41280	COG1609	Transcriptional regulator
SLCG_RS41330	COG0604	alcohol dehydrogenase
SLCG_RS41330	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS41330	COG3321	synthase
SLCG_RS41355	COG1136	(ABC) transporter
SLCG_RS41365	COG1556	Lactate utilization protein
SLCG_RS41370	COG1139	Iron-sulfur cluster binding protein
SLCG_RS41375	COG0247	lactate metabolic process
SLCG_RS41380	COG1070	Carbohydrate kinase
SLCG_RS41385	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS41385	COG3347	Dehydrogenase
SLCG_RS41395	COG2814	Major facilitator Superfamily
SLCG_RS41400	COG3250	beta-galactosidase activity
SLCG_RS41415	COG1129	ABC transporter
SLCG_RS41420	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS41425	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLCG_RS41430	COG1879	ABC-type sugar transport system periplasmic component
SLCG_RS41445	COG1609	Transcriptional regulator
SLCG_RS41460	COG1595	DNA-templated transcription, initiation
SLCG_RS41475	COG1357	PFAM Pentapeptide repeats (8 copies)
SLCG_RS41485	COG1309	transcriptional regulator
SLCG_RS41495	COG2706	6-phosphogluconolactonase activity
SLCG_RS41515	COG2319	Wd-40 repeat
SLCG_RS41515	COG4249	Peptidase C14 caspase catalytic subunit p20
SLCG_RS41520	COG0583	DNA-binding transcription factor activity
SLCG_RS41600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SLCG_RS41600	COG1796	DNA polymerase
SLCG_RS41605	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS41635	COG2124	cytochrome p450
SLCG_RS41645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLCG_RS41665	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS41705	COG0531	amino acid
SLCG_RS41725	COG0435	Glutathione S-transferase
SLCG_RS41740	COG2124	cytochrome p450
SLCG_RS41755	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SLCG_RS41775	COG0667	Aldo Keto reductase
SLCG_RS41810	COG3250	beta-galactosidase activity
SLCG_RS41830	COG1132	(ABC) transporter
SLCG_RS41840	COG0515	serine threonine protein kinase
SLCG_RS41850	COG0517	IMP dehydrogenase activity
SLCG_RS41895	COG0515	serine threonine protein kinase
SLCG_RS41900	COG1960	acyl-CoA dehydrogenase activity
SLCG_RS41945	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SLCG_RS41985	COG0789	Transcriptional regulator
SLCG_RS42005	COG1819	glycosyl
SLCG_RS42030	COG2814	Major facilitator Superfamily
SLCG_RS42045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SLCG_RS42050	COG1120	ATPase activity
SLCG_RS42055	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS42060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLCG_RS42070	COG1132	(ABC) transporter
SLCG_RS42090	COG4221	oxidoreductase activity
SLCG_RS42095	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS42120	COG2182	Extracellular solute-binding protein
SLCG_RS42125	COG0395	ABC-type sugar transport system, permease component
SLCG_RS42130	COG1175	transmembrane transport
SLCG_RS42135	COG1846	Transcriptional regulator
SLCG_RS42135	COG1940	carbohydrate kinase activity
SLCG_RS42155	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SLCG_RS42170	COG0673	inositol 2-dehydrogenase activity
SLCG_RS42180	COG1309	transcriptional regulator
SLCG_RS42235	COG1940	carbohydrate kinase activity
SLCG_RS42245	COG1175	transmembrane transport
SLCG_RS42250	COG0395	ABC-type sugar transport system, permease component
SLCG_RS42270	COG1072	(Pantothenic acid kinase))
SLCG_RS42300	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLCG_RS42305	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SLCG_RS42350	COG0673	inositol 2-dehydrogenase activity
SLCG_RS42355	COG0667	Aldo Keto reductase
SLCG_RS42385	COG1741	Belongs to the pirin family
SLCG_RS42430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLCG_RS42435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SLCG_RS42440	COG2080	2 iron, 2 sulfur cluster binding
SLCG_RS42485	COG3321	synthase
SLCG_RS42485	COG1028	Short-chain dehydrogenase reductase Sdr
SLCG_RS42485	COG0604	alcohol dehydrogenase
SLCG_RS42490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLCG_RS42505	COG3290	protein histidine kinase activity
SLCG_RS42540	COG4249	Peptidase C14 caspase catalytic subunit p20
SLCG_RS42540	COG2319	Wd-40 repeat
SLCG_RS42540	COG4249	Peptidase C14 caspase catalytic subunit p20
SLCG_RS42540	COG2319	Wd-40 repeat
SLCG_RS42590	COG1473	amidohydrolase
SLCG_RS42625	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SLCG_RS42640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SLCG_RS42655	COG1012	belongs to the aldehyde dehydrogenase family
SLCG_RS42655	COG1454	alcohol dehydrogenase
SLCG_RS42700	COG0045	succinate-CoA ligase (ADP-forming) activity
SLCG_RS42700	COG1042	CoA-binding domain protein
SLCG_RS42700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLCG_RS42730	COG0574	Belongs to the PEP-utilizing enzyme family
SLCG_RS42730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLCG_RS42750	COG1366	Belongs to the anti-sigma-factor antagonist family
SLCG_RS42755	COG1063	alcohol dehydrogenase
SLCG_RS42790	COG0667	Aldo Keto reductase
SLCG_RS42805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLCG_RS42870	COG2192	nodulation
SLCG_RS42920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SLCG_RS42930	COG4191	Histidine kinase
SLCG_RS42950	COG4716	Myosin-crossreactive antigen
SLCG_RS42970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLCG_RS42995	COG1733	regulation of RNA biosynthetic process
SLCG_RS43025	COG1846	Transcriptional regulator
SLCG_RS43035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLCG_RS43040	COG2326	polyphosphate kinase activity