locus-tag	class	description
SLINC_RS00015	COG1024	Enoyl-CoA hydratase
SLINC_RS00015	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS00030	COG1902	pentaerythritol trinitrate reductase activity
SLINC_RS00065	COG1309	transcriptional regulator
SLINC_RS00090	COG1309	transcriptional regulator
SLINC_RS00095	COG1609	Transcriptional regulator
SLINC_RS00140	COG0604	alcohol dehydrogenase
SLINC_RS00140	COG3321	synthase
SLINC_RS00155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLINC_RS00165	COG1309	transcriptional regulator
SLINC_RS00170	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS00175	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS00180	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS00190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS00215	COG1024	Enoyl-CoA hydratase
SLINC_RS00215	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS00225	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS00270	COG1063	alcohol dehydrogenase
SLINC_RS00280	COG1850	ribulose-bisphosphate carboxylase activity
SLINC_RS00395	COG3547	Transposase (IS116 IS110 IS902 family)
SLINC_RS00410	COG0326	Molecular chaperone. Has ATPase activity
SLINC_RS00450	COG2814	Major facilitator Superfamily
SLINC_RS00455	COG0513	Belongs to the DEAD box helicase family
SLINC_RS00465	COG3328	transposase activity
SLINC_RS00480	COG1902	pentaerythritol trinitrate reductase activity
SLINC_RS00485	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS00495	COG1309	transcriptional regulator
SLINC_RS00500	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SLINC_RS00510	COG1082	Xylose isomerase domain protein TIM barrel
SLINC_RS00515	COG0673	inositol 2-dehydrogenase activity
SLINC_RS00530	COG1609	Transcriptional regulator
SLINC_RS00580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS00585	COG0515	serine threonine protein kinase
SLINC_RS00585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLINC_RS00605	COG0702	epimerase
SLINC_RS00650	COG2226	methyltransferase
SLINC_RS00705	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SLINC_RS00705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLINC_RS00780	COG0583	DNA-binding transcription factor activity
SLINC_RS00810	COG2226	methyltransferase
SLINC_RS00850	COG0456	acetyltransferase
SLINC_RS00955	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLINC_RS01015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLINC_RS01060	COG1595	DNA-templated transcription, initiation
SLINC_RS01075	COG1252	NADH dehydrogenase
SLINC_RS01080	COG1595	DNA-templated transcription, initiation
SLINC_RS01085	COG0494	nUDIX hydrolase
SLINC_RS01115	COG1309	transcriptional regulator
SLINC_RS01120	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS01150	COG0395	ABC-type sugar transport system, permease component
SLINC_RS01170	COG0577	efflux transmembrane transporter activity
SLINC_RS01170	COG1136	(ABC) transporter
SLINC_RS01175	COG1136	(ABC) transporter
SLINC_RS01190	COG0745	RESPONSE REGULATOR receiver
SLINC_RS01195	COG2205	protein histidine kinase activity
SLINC_RS01200	COG1733	regulation of RNA biosynthetic process
SLINC_RS01215	COG1120	ATPase activity
SLINC_RS01220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS01260	COG2226	methyltransferase
SLINC_RS01310	COG1733	regulation of RNA biosynthetic process
SLINC_RS01360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS01370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLINC_RS01390	COG2226	methyltransferase
SLINC_RS01395	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SLINC_RS01425	COG0746	molybdenum cofactor guanylyltransferase activity
SLINC_RS01430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SLINC_RS01435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLINC_RS01465	COG0384	phenazine biosynthesis protein PhzF
SLINC_RS01470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS01480	COG0488	(ABC) transporter
SLINC_RS01505	COG4585	Histidine kinase
SLINC_RS01510	COG2197	response regulator
SLINC_RS01515	COG1695	Transcriptional regulator
SLINC_RS01550	COG1595	DNA-templated transcription, initiation
SLINC_RS01565	COG4585	Histidine kinase
SLINC_RS01570	COG2409	Drug exporters of the RND superfamily
SLINC_RS01585	COG0116	Belongs to the methyltransferase superfamily
SLINC_RS01585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SLINC_RS01600	COG0346	lactoylglutathione lyase activity
SLINC_RS01625	COG3903	Transcriptional regulator
SLINC_RS01625	COG3629	intracellular signal transduction
SLINC_RS01630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS01665	COG1414	Transcriptional regulator
SLINC_RS01675	COG0765	amino acid transport
SLINC_RS01680	COG0765	amino acid transport
SLINC_RS01685	COG1126	abc transporter atp-binding protein
SLINC_RS01690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLINC_RS01715	COG3903	Transcriptional regulator
SLINC_RS01715	COG3629	intracellular signal transduction
SLINC_RS01725	COG1733	regulation of RNA biosynthetic process
SLINC_RS01730	COG0747	negative chemotaxis
SLINC_RS01740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLINC_RS01745	COG0444	Belongs to the ABC transporter superfamily
SLINC_RS01750	COG4608	Belongs to the ABC transporter superfamily
SLINC_RS01770	COG1252	NADH dehydrogenase
SLINC_RS01780	COG0823	Involved in the tonB-independent uptake of proteins
SLINC_RS01780	COG1506	peptidase
SLINC_RS01855	COG2353	YceI-like domain
SLINC_RS01860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLINC_RS01880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SLINC_RS01890	COG0577	efflux transmembrane transporter activity
SLINC_RS01890	COG1136	(ABC) transporter
SLINC_RS01900	COG2197	response regulator
SLINC_RS01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS01925	COG1120	ATPase activity
SLINC_RS01965	COG3629	intracellular signal transduction
SLINC_RS01965	COG3903	Transcriptional regulator
SLINC_RS01970	COG0596	Alpha beta hydrolase
SLINC_RS01990	COG0789	Transcriptional regulator
SLINC_RS01995	COG0009	L-threonylcarbamoyladenylate synthase
SLINC_RS02005	COG3300	MHYT domain
SLINC_RS02005	COG5001	Diguanylate cyclase
SLINC_RS02040	COG1621	beta-fructofuranosidase activity
SLINC_RS02050	COG1175	transmembrane transport
SLINC_RS02055	COG0395	ABC-type sugar transport system, permease component
SLINC_RS02065	COG1609	Transcriptional regulator
SLINC_RS02070	COG0656	L-ascorbic acid biosynthetic process
SLINC_RS02080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS02090	COG1846	Transcriptional regulator
SLINC_RS02110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SLINC_RS02110	COG0512	Glutamine amidotransferase of anthranilate synthase
SLINC_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS02140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLINC_RS02145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLINC_RS02155	COG2030	dehydratase
SLINC_RS02165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS02170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLINC_RS02195	COG2207	Transcriptional regulator
SLINC_RS02200	COG2223	nitrite transmembrane transporter activity
SLINC_RS02225	COG0745	RESPONSE REGULATOR receiver
SLINC_RS02240	COG2197	response regulator
SLINC_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS02255	COG1793	dna ligase
SLINC_RS02280	COG0181	hydroxymethylbilane synthase activity
SLINC_RS02290	COG0842	Transport permease protein
SLINC_RS02330	COG0366	Alpha amylase catalytic
SLINC_RS02340	COG3281	Trehalose synthase
SLINC_RS02345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLINC_RS02350	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLINC_RS02385	COG1366	Belongs to the anti-sigma-factor antagonist family
SLINC_RS02390	COG1366	Belongs to the anti-sigma-factor antagonist family
SLINC_RS02395	COG2172	sigma factor antagonist activity
SLINC_RS02410	COG1252	NADH dehydrogenase
SLINC_RS02455	COG1982	Orn Lys Arg decarboxylase major
SLINC_RS02465	COG0477	Major facilitator Superfamily
SLINC_RS02500	COG5002	protein histidine kinase activity
SLINC_RS02505	COG0745	RESPONSE REGULATOR receiver
SLINC_RS02520	COG3189	MarR family transcriptional regulator
SLINC_RS02540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLINC_RS02560	COG0492	ferredoxin-NADP+ reductase activity
SLINC_RS02565	COG3852	Histidine kinase
SLINC_RS02575	COG2197	response regulator
SLINC_RS02595	COG3345	alpha-galactosidase
SLINC_RS02600	COG1846	Transcriptional regulator
SLINC_RS02600	COG1940	carbohydrate kinase activity
SLINC_RS02610	COG2340	Cysteine-rich secretory protein family
SLINC_RS02625	COG0142	geranyltranstransferase activity
SLINC_RS02630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SLINC_RS02635	COG0515	serine threonine protein kinase
SLINC_RS02635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLINC_RS02645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS02675	COG0667	Aldo Keto reductase
SLINC_RS02705	COG0328	RNA-DNA hybrid ribonuclease activity
SLINC_RS02715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLINC_RS02725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLINC_RS02745	COG0596	Alpha beta hydrolase
SLINC_RS02750	COG0740	serine-type endopeptidase activity
SLINC_RS02755	COG0740	serine-type endopeptidase activity
SLINC_RS02760	COG1396	sequence-specific DNA binding
SLINC_RS02765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SLINC_RS02770	COG1191	sigma factor activity
SLINC_RS02795	COG0515	serine threonine protein kinase
SLINC_RS02795	COG2815	serine threonine protein kinase
SLINC_RS02805	COG1716	ATPase activity
SLINC_RS02805	COG1131	(ABC) transporter
SLINC_RS02805	COG0842	Transport permease protein
SLINC_RS02825	COG0667	Aldo Keto reductase
SLINC_RS02830	COG0583	DNA-binding transcription factor activity
SLINC_RS02840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLINC_RS02845	COG0346	lactoylglutathione lyase activity
SLINC_RS02850	COG0412	Dienelactone hydrolase
SLINC_RS02860	COG0667	Aldo Keto reductase
SLINC_RS02870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SLINC_RS02870	COG4106	trans-aconitate 2-methyltransferase activity
SLINC_RS02875	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS02895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS02905	COG0431	NADPH-dependent FMN reductase
SLINC_RS02920	COG0583	DNA-binding transcription factor activity
SLINC_RS03005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SLINC_RS03010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLINC_RS03015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLINC_RS03035	COG3387	PFAM Glycoside hydrolase 15-related
SLINC_RS03055	COG0367	asparagine synthase
SLINC_RS03110	COG0589	response to stress
SLINC_RS03135	COG1024	Enoyl-CoA hydratase
SLINC_RS03155	COG2267	carboxylic ester hydrolase activity
SLINC_RS03205	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS03210	COG2366	antibiotic biosynthetic process
SLINC_RS03235	COG2188	Transcriptional regulator
SLINC_RS03250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS03260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SLINC_RS03275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLINC_RS03280	COG1126	abc transporter atp-binding protein
SLINC_RS03285	COG0765	amino acid transport
SLINC_RS03295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS03300	COG0745	RESPONSE REGULATOR receiver
SLINC_RS03355	COG1609	Transcriptional regulator
SLINC_RS03360	COG1653	transport
SLINC_RS03375	COG0366	Alpha amylase catalytic
SLINC_RS03395	COG5297	Belongs to the glycosyl hydrolase family 6
SLINC_RS03410	COG0300	oxidoreductase activity
SLINC_RS03420	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SLINC_RS03425	COG4585	Histidine kinase
SLINC_RS03430	COG2197	response regulator
SLINC_RS03460	COG1522	sequence-specific DNA binding
SLINC_RS03495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS03500	COG0778	Nitroreductase
SLINC_RS03520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SLINC_RS03525	COG0738	Major facilitator superfamily
SLINC_RS03535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SLINC_RS03570	COG3250	beta-galactosidase activity
SLINC_RS03580	COG2755	lipolytic protein G-D-S-L family
SLINC_RS03605	COG2070	2-Nitropropane dioxygenase
SLINC_RS03610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS03630	COG2815	serine threonine protein kinase
SLINC_RS03630	COG0515	serine threonine protein kinase
SLINC_RS03645	COG4171	peptide transport system, permease
SLINC_RS03670	COG0789	Transcriptional regulator
SLINC_RS03705	COG1309	transcriptional regulator
SLINC_RS03715	COG0300	oxidoreductase activity
SLINC_RS03720	COG0604	alcohol dehydrogenase
SLINC_RS03720	COG3321	synthase
SLINC_RS03745	COG2226	methyltransferase
SLINC_RS03780	COG1609	Transcriptional regulator
SLINC_RS03790	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLINC_RS03800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLINC_RS03815	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLINC_RS03825	COG1609	Transcriptional regulator
SLINC_RS03830	COG1609	Transcriptional regulator
SLINC_RS03855	COG1609	Transcriptional regulator
SLINC_RS03860	COG1175	transmembrane transport
SLINC_RS03865	COG0395	ABC-type sugar transport system, permease component
SLINC_RS03875	COG0673	inositol 2-dehydrogenase activity
SLINC_RS03885	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS03885	COG2319	Wd-40 repeat
SLINC_RS03920	COG0604	alcohol dehydrogenase
SLINC_RS03920	COG3321	synthase
SLINC_RS03955	COG1404	Belongs to the peptidase S8 family
SLINC_RS03975	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS04010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS04020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS04045	COG0137	argininosuccinate synthase activity
SLINC_RS04070	COG2376	Dihydroxyacetone kinase
SLINC_RS04080	COG1461	Dihydroxyacetone kinase
SLINC_RS04120	COG1309	transcriptional regulator
SLINC_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS04160	COG1902	pentaerythritol trinitrate reductase activity
SLINC_RS04160	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLINC_RS04180	COG0475	glutathione-regulated potassium exporter activity
SLINC_RS04225	COG2890	protein-(glutamine-N5) methyltransferase activity
SLINC_RS04245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLINC_RS04265	COG3458	cephalosporin-C deacetylase activity
SLINC_RS04270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS04275	COG2226	methyltransferase
SLINC_RS04290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS04295	COG3284	Transcriptional regulator
SLINC_RS04305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SLINC_RS04320	COG2066	Belongs to the glutaminase family
SLINC_RS04335	COG1113	amino acid transport
SLINC_RS04340	COG2186	Transcriptional regulator
SLINC_RS04345	COG1968	undecaprenyl-diphosphatase activity
SLINC_RS04350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLINC_RS04355	COG1993	acr, cog1993
SLINC_RS04360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLINC_RS04410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS04415	COG1116	anion transmembrane transporter activity
SLINC_RS04440	COG0277	FAD linked oxidase domain protein
SLINC_RS04455	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS04510	COG0443	Heat shock 70 kDa protein
SLINC_RS04555	COG3386	PFAM SMP-30 Gluconolaconase
SLINC_RS04565	COG0800	Aldolase
SLINC_RS04575	COG0129	dihydroxy-acid dehydratase activity
SLINC_RS04580	COG1063	alcohol dehydrogenase
SLINC_RS04620	COG0395	ABC-type sugar transport system, permease component
SLINC_RS04625	COG1175	transmembrane transport
SLINC_RS04635	COG1609	Transcriptional regulator
SLINC_RS04645	COG3940	Belongs to the glycosyl hydrolase 43 family
SLINC_RS04660	COG1819	glycosyl
SLINC_RS04665	COG3973	AAA domain
SLINC_RS04670	COG2814	Major facilitator Superfamily
SLINC_RS04680	COG1846	Transcriptional regulator
SLINC_RS04685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLINC_RS04700	COG1937	Protein conserved in bacteria
SLINC_RS04705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SLINC_RS04710	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS04710	COG2319	Wd-40 repeat
SLINC_RS04720	COG2186	Transcriptional regulator
SLINC_RS04730	COG0134	indole-3-glycerol-phosphate synthase activity
SLINC_RS04735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS04735	COG0723	plastoquinol--plastocyanin reductase activity
SLINC_RS04745	COG0667	Aldo Keto reductase
SLINC_RS04760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLINC_RS04775	COG3842	ATPase activity
SLINC_RS04785	COG3608	succinylglutamate desuccinylase aspartoacylase
SLINC_RS04810	COG0247	lactate metabolic process
SLINC_RS04810	COG0277	FAD linked oxidase domain protein
SLINC_RS04815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLINC_RS04835	COG2409	Drug exporters of the RND superfamily
SLINC_RS04840	COG0477	Major facilitator Superfamily
SLINC_RS04850	COG2197	response regulator
SLINC_RS04855	COG3851	Histidine kinase
SLINC_RS04860	COG2409	Drug exporters of the RND superfamily
SLINC_RS04865	COG0789	Transcriptional regulator
SLINC_RS04880	COG0640	Transcriptional regulator
SLINC_RS04885	COG2072	flavoprotein involved in K transport
SLINC_RS04890	COG0798	PFAM Bile acid sodium symporter
SLINC_RS04900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLINC_RS04920	COG1090	epimerase
SLINC_RS04935	COG0604	alcohol dehydrogenase
SLINC_RS04945	COG2188	Transcriptional regulator
SLINC_RS04960	COG0596	Alpha beta hydrolase
SLINC_RS04970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLINC_RS04975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLINC_RS04985	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS04990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLINC_RS05010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SLINC_RS05030	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS05055	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SLINC_RS05060	COG1215	transferase activity, transferring glycosyl groups
SLINC_RS05095	COG1349	DNA-binding transcription factor activity
SLINC_RS05110	COG1366	Belongs to the anti-sigma-factor antagonist family
SLINC_RS05110	COG2208	phosphoserine phosphatase activity
SLINC_RS05110	COG2172	sigma factor antagonist activity
SLINC_RS05120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLINC_RS05135	COG0577	efflux transmembrane transporter activity
SLINC_RS05175	COG0698	ribose 5-phosphate isomerase
SLINC_RS05180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SLINC_RS05195	COG1940	carbohydrate kinase activity
SLINC_RS05205	COG2813	Specifically methylates the guanine in position
SLINC_RS05225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLINC_RS05230	COG1349	DNA-binding transcription factor activity
SLINC_RS05235	COG3387	PFAM Glycoside hydrolase 15-related
SLINC_RS05240	COG0477	Major facilitator Superfamily
SLINC_RS05260	COG0395	ABC-type sugar transport system, permease component
SLINC_RS05265	COG1175	transmembrane transport
SLINC_RS05300	COG2197	response regulator
SLINC_RS05325	COG4565	transcriptional regulatory protein
SLINC_RS05350	COG1316	TRANSCRIPTIONal
SLINC_RS05405	COG1126	abc transporter atp-binding protein
SLINC_RS05410	COG0765	amino acid transport
SLINC_RS05415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLINC_RS05420	COG3835	regulator
SLINC_RS05430	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SLINC_RS05440	COG1609	Transcriptional regulator
SLINC_RS05445	COG0667	Aldo Keto reductase
SLINC_RS05460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLINC_RS05480	COG2186	Transcriptional regulator
SLINC_RS05485	COG2267	carboxylic ester hydrolase activity
SLINC_RS05505	COG0444	Belongs to the ABC transporter superfamily
SLINC_RS05510	COG4608	Belongs to the ABC transporter superfamily
SLINC_RS05525	COG1454	alcohol dehydrogenase
SLINC_RS05530	COG3485	protocatechuate 3,4-dioxygenase
SLINC_RS05540	COG3284	Transcriptional regulator
SLINC_RS05575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SLINC_RS05580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLINC_RS05595	COG1349	DNA-binding transcription factor activity
SLINC_RS05635	COG0477	Major facilitator Superfamily
SLINC_RS05640	COG4948	Mandelate Racemase Muconate Lactonizing
SLINC_RS05645	COG2610	gluconate transmembrane transporter activity
SLINC_RS05650	COG1414	Transcriptional regulator
SLINC_RS05670	COG2223	nitrite transmembrane transporter activity
SLINC_RS05690	COG0596	Alpha beta hydrolase
SLINC_RS05705	COG0789	Transcriptional regulator
SLINC_RS05710	COG0659	secondary active sulfate transmembrane transporter activity
SLINC_RS05720	COG3795	YCII-related domain
SLINC_RS05725	COG4941	Belongs to the sigma-70 factor family
SLINC_RS05730	COG0583	DNA-binding transcription factor activity
SLINC_RS05750	COG1802	Transcriptional regulator
SLINC_RS05770	COG0748	coenzyme F420 binding
SLINC_RS05780	COG1733	regulation of RNA biosynthetic process
SLINC_RS05795	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SLINC_RS05800	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SLINC_RS05805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SLINC_RS05820	COG0745	RESPONSE REGULATOR receiver
SLINC_RS05825	COG2205	protein histidine kinase activity
SLINC_RS05835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLINC_RS05835	COG0515	serine threonine protein kinase
SLINC_RS05870	COG1609	Transcriptional regulator
SLINC_RS05890	COG1131	(ABC) transporter
SLINC_RS05920	COG1121	(ABC) transporter
SLINC_RS05925	COG0488	(ABC) transporter
SLINC_RS05940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLINC_RS05950	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS05965	COG0596	Alpha beta hydrolase
SLINC_RS05975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS05990	COG0697	spore germination
SLINC_RS06005	COG0673	inositol 2-dehydrogenase activity
SLINC_RS06015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLINC_RS06020	COG0583	DNA-binding transcription factor activity
SLINC_RS06025	COG2851	Citrate transporter
SLINC_RS06060	COG2197	response regulator
SLINC_RS06065	COG4585	Histidine kinase
SLINC_RS06070	COG2409	Drug exporters of the RND superfamily
SLINC_RS06075	COG3903	Transcriptional regulator
SLINC_RS06075	COG3629	intracellular signal transduction
SLINC_RS06090	COG0445	tRNA wobble uridine modification
SLINC_RS06105	COG4608	Belongs to the ABC transporter superfamily
SLINC_RS06110	COG0444	Belongs to the ABC transporter superfamily
SLINC_RS06115	COG0601	transmembrane transport
SLINC_RS06120	COG0747	negative chemotaxis
SLINC_RS06125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLINC_RS06130	COG1660	Displays ATPase and GTPase activities
SLINC_RS06140	COG1090	epimerase
SLINC_RS06160	COG2815	serine threonine protein kinase
SLINC_RS06160	COG0515	serine threonine protein kinase
SLINC_RS06175	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SLINC_RS06200	COG0204	Acyl-transferase
SLINC_RS06235	COG0584	glycerophosphoryl diester phosphodiesterase
SLINC_RS06285	COG0671	phosphoesterase, PA-phosphatase related
SLINC_RS06295	COG1309	transcriptional regulator
SLINC_RS06315	COG0493	'glutamate synthase
SLINC_RS06325	COG0640	Transcriptional regulator
SLINC_RS06330	COG1902	pentaerythritol trinitrate reductase activity
SLINC_RS06335	COG3509	depolymerase
SLINC_RS06350	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS06370	COG0187	DNA topoisomerase II activity
SLINC_RS06385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLINC_RS06400	COG2706	6-phosphogluconolactonase activity
SLINC_RS06415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLINC_RS06425	COG1404	Belongs to the peptidase S8 family
SLINC_RS06435	COG1672	PFAM Archaeal ATPase
SLINC_RS06435	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLINC_RS06475	COG1653	transport
SLINC_RS06480	COG1175	transmembrane transport
SLINC_RS06485	COG0395	ABC-type sugar transport system, permease component
SLINC_RS06490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLINC_RS06495	COG4948	Mandelate Racemase Muconate Lactonizing
SLINC_RS06505	COG2197	response regulator
SLINC_RS06535	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SLINC_RS06565	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SLINC_RS06585	COG0246	Mannitol dehydrogenase
SLINC_RS06590	COG0477	Major facilitator Superfamily
SLINC_RS06595	COG1063	alcohol dehydrogenase
SLINC_RS06615	COG0714	Associated with various cellular activities
SLINC_RS06660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS06710	COG0657	acetylesterase activity
SLINC_RS06715	COG0432	Pfam Uncharacterised protein family UPF0047
SLINC_RS06720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS06725	COG1116	anion transmembrane transporter activity
SLINC_RS06745	COG1132	(ABC) transporter
SLINC_RS06755	COG1301	dicarboxylic acid transport
SLINC_RS06770	COG1132	(ABC) transporter
SLINC_RS06775	COG1132	(ABC) transporter
SLINC_RS06785	COG0254	rRNA binding
SLINC_RS06800	COG1946	Acyl-CoA thioesterase
SLINC_RS06810	COG2018	Roadblock/LC7 domain
SLINC_RS06865	COG3239	Fatty acid desaturase
SLINC_RS06870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLINC_RS06890	COG2115	Belongs to the xylose isomerase family
SLINC_RS06900	COG1846	Transcriptional regulator
SLINC_RS06900	COG1940	carbohydrate kinase activity
SLINC_RS06915	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS06945	COG0602	queuosine metabolic process
SLINC_RS06960	COG1609	Transcriptional regulator
SLINC_RS06970	COG1175	transmembrane transport
SLINC_RS06980	COG1472	Belongs to the glycosyl hydrolase 3 family
SLINC_RS06990	COG0129	dihydroxy-acid dehydratase activity
SLINC_RS07040	COG3693	PFAM glycoside hydrolase, family 10
SLINC_RS07060	COG0019	diaminopimelate decarboxylase activity
SLINC_RS07065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLINC_RS07070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLINC_RS07080	COG1169	isochorismate synthase
SLINC_RS07085	COG1021	2,3-dihydroxybenzoate-AMP ligase
SLINC_RS07090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS07090	COG2226	methyltransferase
SLINC_RS07090	COG3433	isochorismatase activity
SLINC_RS07095	COG3433	isochorismatase activity
SLINC_RS07095	COG2226	methyltransferase
SLINC_RS07095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS07130	COG1132	(ABC) transporter
SLINC_RS07130	COG2375	cellular response to nickel ion
SLINC_RS07140	COG0477	Major facilitator Superfamily
SLINC_RS07150	COG4172	Belongs to the ABC transporter superfamily
SLINC_RS07165	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS07165	COG1703	isobutyryl-CoA mutase activity
SLINC_RS07165	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS07175	COG3833	ABC-type maltose transport systems, permease component
SLINC_RS07185	COG2182	Extracellular solute-binding protein
SLINC_RS07205	COG4585	Histidine kinase
SLINC_RS07235	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS07240	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS07255	COG0492	ferredoxin-NADP+ reductase activity
SLINC_RS07260	COG1793	dna ligase
SLINC_RS07280	COG3424	synthase
SLINC_RS07285	COG2124	cytochrome p450
SLINC_RS07295	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS07305	COG0242	peptide deformylase activity
SLINC_RS07310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLINC_RS07315	COG3442	glutamine amidotransferase
SLINC_RS07320	COG0205	6-phosphofructokinase activity
SLINC_RS07340	COG3275	phosphorelay sensor kinase activity
SLINC_RS07345	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLINC_RS07355	COG3279	Response regulator of the LytR AlgR family
SLINC_RS07360	COG1522	sequence-specific DNA binding
SLINC_RS07365	COG1834	amidinotransferase
SLINC_RS07370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLINC_RS07415	COG0829	nickel cation binding
SLINC_RS07420	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SLINC_RS07430	COG0804	urea catabolic process
SLINC_RS07435	COG0832	Belongs to the urease beta subunit family
SLINC_RS07440	COG0831	urea catabolic process
SLINC_RS07445	COG1309	transcriptional regulator
SLINC_RS07470	COG1940	carbohydrate kinase activity
SLINC_RS07495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SLINC_RS07505	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS07515	COG1126	abc transporter atp-binding protein
SLINC_RS07520	COG0765	amino acid transport
SLINC_RS07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLINC_RS07530	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS07540	COG0251	oxidation-reduction process
SLINC_RS07560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS07580	COG0740	serine-type endopeptidase activity
SLINC_RS07600	COG1280	lysine exporter protein (LysE YggA)
SLINC_RS07605	COG0583	DNA-binding transcription factor activity
SLINC_RS07630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SLINC_RS07635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLINC_RS07640	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SLINC_RS07655	COG2226	methyltransferase
SLINC_RS07670	COG1136	(ABC) transporter
SLINC_RS07675	COG0577	efflux transmembrane transporter activity
SLINC_RS07675	COG1136	(ABC) transporter
SLINC_RS07690	COG0456	acetyltransferase
SLINC_RS07715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLINC_RS07720	COG3663	DNA glycosylase
SLINC_RS07740	COG4585	Histidine kinase
SLINC_RS07745	COG2197	response regulator
SLINC_RS07750	COG1940	carbohydrate kinase activity
SLINC_RS07755	COG2188	Transcriptional regulator
SLINC_RS07760	COG1595	DNA-templated transcription, initiation
SLINC_RS07770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS07805	COG1522	sequence-specific DNA binding
SLINC_RS07810	COG0419	ATPase involved in DNA repair
SLINC_RS07815	COG0420	3'-5' exonuclease activity
SLINC_RS07850	COG1739	Uncharacterized protein family UPF0029
SLINC_RS07860	COG0215	cysteine-tRNA ligase activity
SLINC_RS07865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLINC_RS07870	COG3842	ATPase activity
SLINC_RS07880	COG1176	ABC-type spermidine putrescine transport system, permease component I
SLINC_RS07890	COG2188	Transcriptional regulator
SLINC_RS07900	COG1278	Cold shock
SLINC_RS07910	COG1832	CoA-binding protein
SLINC_RS07915	COG0531	amino acid
SLINC_RS07925	COG0640	Transcriptional regulator
SLINC_RS07950	COG0110	maltose O-acetyltransferase activity
SLINC_RS08000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLINC_RS08025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLINC_RS08035	COG0183	Belongs to the thiolase family
SLINC_RS08045	COG1968	undecaprenyl-diphosphatase activity
SLINC_RS08060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SLINC_RS08065	COG0673	inositol 2-dehydrogenase activity
SLINC_RS08070	COG2318	DinB family
SLINC_RS08085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLINC_RS08090	COG0747	negative chemotaxis
SLINC_RS08135	COG0697	spore germination
SLINC_RS08180	COG1695	Transcriptional regulator
SLINC_RS08185	COG2226	methyltransferase
SLINC_RS08220	COG1609	Transcriptional regulator
SLINC_RS08230	COG0395	ABC-type sugar transport system, permease component
SLINC_RS08245	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS08275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLINC_RS08275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLINC_RS08285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SLINC_RS08325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLINC_RS08360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLINC_RS08375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS08380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLINC_RS08405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLINC_RS08415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLINC_RS08420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLINC_RS08455	COG0531	amino acid
SLINC_RS08480	COG2814	Major facilitator Superfamily
SLINC_RS08485	COG4336	lyase activity
SLINC_RS08490	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SLINC_RS08495	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SLINC_RS08500	COG1984	allophanate hydrolase subunit 2
SLINC_RS08505	COG2755	lipolytic protein G-D-S-L family
SLINC_RS08510	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS08540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS08545	COG2364	Membrane
SLINC_RS08555	COG2270	Major facilitator Superfamily
SLINC_RS08570	COG1216	Glycosyl transferase, family 2
SLINC_RS08590	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS08635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SLINC_RS08640	COG0140	phosphoribosyl-ATP diphosphatase activity
SLINC_RS08645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SLINC_RS08650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLINC_RS08650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLINC_RS08655	COG3201	nicotinamide mononucleotide transporter
SLINC_RS08665	COG1846	Transcriptional regulator
SLINC_RS08665	COG1940	carbohydrate kinase activity
SLINC_RS08670	COG2223	nitrite transmembrane transporter activity
SLINC_RS08675	COG2233	PERMEase
SLINC_RS08695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLINC_RS08720	COG0531	amino acid
SLINC_RS08745	COG3629	intracellular signal transduction
SLINC_RS08745	COG3903	Transcriptional regulator
SLINC_RS08755	COG2390	Transcriptional regulator
SLINC_RS08760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SLINC_RS08765	COG2409	Drug exporters of the RND superfamily
SLINC_RS08775	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SLINC_RS08790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLINC_RS08800	COG1758	RNA polymerase activity
SLINC_RS08805	COG0194	GDP metabolic process
SLINC_RS08815	COG0284	orotidine-5'-phosphate decarboxylase activity
SLINC_RS08820	COG0167	dihydroorotate dehydrogenase activity
SLINC_RS08825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SLINC_RS08830	COG0505	Belongs to the CarA family
SLINC_RS08840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLINC_RS08845	COG0540	Belongs to the ATCase OTCase family
SLINC_RS08850	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SLINC_RS08860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SLINC_RS08865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SLINC_RS08870	COG0006	proline dipeptidase activity
SLINC_RS08880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SLINC_RS08885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SLINC_RS08890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SLINC_RS08895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SLINC_RS08910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SLINC_RS08915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SLINC_RS08935	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SLINC_RS08950	COG1131	(ABC) transporter
SLINC_RS08960	COG4585	Histidine kinase
SLINC_RS08965	COG2197	response regulator
SLINC_RS08970	COG0124	histidyl-tRNA synthetase
SLINC_RS08980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SLINC_RS08985	COG1196	nuclear chromosome segregation
SLINC_RS08990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLINC_RS08995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SLINC_RS09000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLINC_RS09005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLINC_RS09015	COG2255	four-way junction helicase activity
SLINC_RS09020	COG0632	four-way junction helicase activity
SLINC_RS09025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SLINC_RS09030	COG0217	transcriptional regulatory protein
SLINC_RS09035	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SLINC_RS09040	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SLINC_RS09050	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS09055	COG1560	Kdo2-lipid A biosynthetic process
SLINC_RS09060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SLINC_RS09080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLINC_RS09095	COG5002	protein histidine kinase activity
SLINC_RS09095	COG2176	DNA-directed DNA polymerase activity
SLINC_RS09125	COG0395	ABC-type sugar transport system, permease component
SLINC_RS09130	COG1175	transmembrane transport
SLINC_RS09135	COG1653	transport
SLINC_RS09240	COG1648	precorrin-2 dehydrogenase activity
SLINC_RS09240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SLINC_RS09245	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLINC_RS09260	COG1464	Belongs to the NlpA lipoprotein family
SLINC_RS09265	COG2011	ABC-type metal ion transport system permease component
SLINC_RS09270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLINC_RS09295	COG0584	glycerophosphoryl diester phosphodiesterase
SLINC_RS09300	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS09300	COG0204	Acyl-transferase
SLINC_RS09305	COG2205	protein histidine kinase activity
SLINC_RS09310	COG0745	RESPONSE REGULATOR receiver
SLINC_RS09315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLINC_RS09320	COG2304	oxidoreductase activity
SLINC_RS09330	COG0714	Associated with various cellular activities
SLINC_RS09340	COG0477	Major facilitator Superfamily
SLINC_RS09355	COG0165	Argininosuccinate lyase
SLINC_RS09390	COG1438	arginine binding
SLINC_RS09395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLINC_RS09400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SLINC_RS09405	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SLINC_RS09410	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SLINC_RS09415	COG1120	ATPase activity
SLINC_RS09420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLINC_RS09445	COG2207	Transcriptional regulator
SLINC_RS09445	COG3708	Transcriptional regulator
SLINC_RS09475	COG0697	spore germination
SLINC_RS09485	COG1649	PFAM Uncharacterised BCR, COG1649
SLINC_RS09515	COG0072	phenylalanine-tRNA ligase activity
SLINC_RS09515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLINC_RS09520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SLINC_RS09525	COG5002	protein histidine kinase activity
SLINC_RS09530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SLINC_RS09535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SLINC_RS09540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SLINC_RS09545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SLINC_RS09590	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS09595	COG0174	glutamine synthetase
SLINC_RS09605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SLINC_RS09630	COG4176	ABC-type proline glycine betaine transport system permease component
SLINC_RS09640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLINC_RS09670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SLINC_RS09700	COG2124	cytochrome p450
SLINC_RS09770	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SLINC_RS09775	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLINC_RS09785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SLINC_RS09795	COG2205	protein histidine kinase activity
SLINC_RS09800	COG0805	protein transport
SLINC_RS09805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLINC_RS09835	COG0545	Peptidyl-prolyl cis-trans isomerase
SLINC_RS09840	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLINC_RS09850	COG1609	Transcriptional regulator
SLINC_RS09855	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLINC_RS09860	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLINC_RS09870	COG4122	O-methyltransferase activity
SLINC_RS09875	COG1222	aaa ATPase
SLINC_RS09895	COG0517	IMP dehydrogenase activity
SLINC_RS09895	COG1994	Peptidase M50
SLINC_RS09905	COG2197	response regulator
SLINC_RS09915	COG4166	transmembrane transport
SLINC_RS09920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLINC_RS09925	COG0646	methionine synthase
SLINC_RS09925	COG1410	methionine synthase
SLINC_RS09930	COG1414	Transcriptional regulator
SLINC_RS09935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLINC_RS09940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLINC_RS09945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SLINC_RS09950	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
SLINC_RS09960	COG1129	ABC transporter
SLINC_RS09970	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SLINC_RS09975	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SLINC_RS09980	COG0235	Class ii aldolase
SLINC_RS09985	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SLINC_RS09985	COG0235	Class ii aldolase
SLINC_RS09995	COG2186	Transcriptional regulator
SLINC_RS10010	COG1404	Belongs to the peptidase S8 family
SLINC_RS10020	COG0215	cysteine-tRNA ligase activity
SLINC_RS10035	COG0588	phosphoglycerate mutase activity
SLINC_RS10040	COG0598	Magnesium transport protein CorA
SLINC_RS10050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS10055	COG0667	Aldo Keto reductase
SLINC_RS10085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLINC_RS10100	COG0308	aminopeptidase N
SLINC_RS10110	COG3012	SEC-C Motif Domain Protein
SLINC_RS10115	COG2186	Transcriptional regulator
SLINC_RS10120	COG3265	gluconokinase activity
SLINC_RS10130	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS10135	COG1063	alcohol dehydrogenase
SLINC_RS10175	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLINC_RS10180	COG2149	membrane
SLINC_RS10210	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS10220	COG3876	Protein conserved in bacteria
SLINC_RS10275	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS10285	COG0640	Transcriptional regulator
SLINC_RS10295	COG0477	Major facilitator Superfamily
SLINC_RS10325	COG2851	Citrate transporter
SLINC_RS10330	COG0243	molybdopterin cofactor binding
SLINC_RS10345	COG1309	transcriptional regulator
SLINC_RS10355	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SLINC_RS10360	COG2188	Transcriptional regulator
SLINC_RS10395	COG1595	DNA-templated transcription, initiation
SLINC_RS10415	COG2815	serine threonine protein kinase
SLINC_RS10415	COG0515	serine threonine protein kinase
SLINC_RS10420	COG2755	lipolytic protein G-D-S-L family
SLINC_RS10445	COG1216	Glycosyl transferase, family 2
SLINC_RS10450	COG0726	polysaccharide deacetylase
SLINC_RS10450	COG1649	PFAM Uncharacterised BCR, COG1649
SLINC_RS10475	COG1725	Transcriptional regulator
SLINC_RS10520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SLINC_RS10525	COG0587	DNA-directed DNA polymerase activity
SLINC_RS10540	COG0330	HflC and HflK could
SLINC_RS10555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS10565	COG0765	amino acid transport
SLINC_RS10570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLINC_RS10580	COG1799	cell septum assembly
SLINC_RS10585	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS10590	COG0477	Major facilitator Superfamily
SLINC_RS10600	COG0671	phosphoesterase, PA-phosphatase related
SLINC_RS10610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SLINC_RS10635	COG1129	ABC transporter
SLINC_RS10645	COG1652	LysM domain
SLINC_RS10660	COG1160	GTP binding
SLINC_RS10670	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SLINC_RS10700	COG1397	ADP-ribosylglycohydrolase
SLINC_RS10710	COG0477	Major facilitator Superfamily
SLINC_RS10725	COG1187	pseudouridine synthase activity
SLINC_RS10730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SLINC_RS10735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SLINC_RS10750	COG0686	Belongs to the AlaDH PNT family
SLINC_RS10760	COG0494	nUDIX hydrolase
SLINC_RS10765	COG0504	CTP synthase activity
SLINC_RS10770	COG3387	PFAM Glycoside hydrolase 15-related
SLINC_RS10785	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS10790	COG0497	DNA recombination
SLINC_RS10795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SLINC_RS10810	COG1120	ATPase activity
SLINC_RS10815	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS10820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS10830	COG0647	UMP catabolic process
SLINC_RS10870	COG2094	Belongs to the DNA glycosylase MPG family
SLINC_RS10880	COG1881	PFAM PEBP family protein
SLINC_RS10900	COG1119	ATPase activity
SLINC_RS10920	COG2197	response regulator
SLINC_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS10935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SLINC_RS10945	COG1131	(ABC) transporter
SLINC_RS10945	COG0842	Transport permease protein
SLINC_RS10945	COG1716	ATPase activity
SLINC_RS10955	COG0560	Phosphoserine phosphatase
SLINC_RS10955	COG3830	Belongs to the UPF0237 family
SLINC_RS10960	COG0588	phosphoglycerate mutase activity
SLINC_RS10975	COG2186	Transcriptional regulator
SLINC_RS10990	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS10995	COG0312	modulator of DNA gyrase
SLINC_RS11005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SLINC_RS11025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SLINC_RS11030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLINC_RS11050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLINC_RS11060	COG2176	DNA-directed DNA polymerase activity
SLINC_RS11075	COG3387	PFAM Glycoside hydrolase 15-related
SLINC_RS11115	COG1024	Enoyl-CoA hydratase
SLINC_RS11125	COG0488	(ABC) transporter
SLINC_RS11145	COG0235	Class ii aldolase
SLINC_RS11165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SLINC_RS11170	COG1492	cobalamin metabolic process
SLINC_RS11190	COG1797	cobyrinic acid a,c-diamide synthase activity
SLINC_RS11250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLINC_RS11260	COG0765	amino acid transport
SLINC_RS11270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SLINC_RS11275	COG0456	acetyltransferase
SLINC_RS11280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLINC_RS11285	COG1917	Cupin 2, conserved barrel domain protein
SLINC_RS11290	COG5285	phytanoyl-CoA dioxygenase
SLINC_RS11300	COG1595	DNA-templated transcription, initiation
SLINC_RS11305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLINC_RS11335	COG1414	Transcriptional regulator
SLINC_RS11345	COG4585	Histidine kinase
SLINC_RS11350	COG2197	response regulator
SLINC_RS11360	COG2252	PERMEase
SLINC_RS11365	COG1595	DNA-templated transcription, initiation
SLINC_RS11395	COG4733	cellulase activity
SLINC_RS11410	COG4677	pectinesterase activity
SLINC_RS11415	COG4677	pectinesterase activity
SLINC_RS11425	COG2755	lipolytic protein G-D-S-L family
SLINC_RS11435	COG4677	pectinesterase activity
SLINC_RS11440	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS11455	COG3866	Pectate lyase
SLINC_RS11460	COG0395	ABC-type sugar transport system, permease component
SLINC_RS11465	COG1175	transmembrane transport
SLINC_RS11480	COG1802	Transcriptional regulator
SLINC_RS11505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLINC_RS11510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLINC_RS11515	COG1349	DNA-binding transcription factor activity
SLINC_RS11530	COG0395	ABC-type sugar transport system, permease component
SLINC_RS11535	COG1063	alcohol dehydrogenase
SLINC_RS11560	COG0395	ABC-type sugar transport system, permease component
SLINC_RS11565	COG1175	transmembrane transport
SLINC_RS11585	COG1802	Transcriptional regulator
SLINC_RS11640	COG1295	ribonuclease BN
SLINC_RS11640	COG1959	2 iron, 2 sulfur cluster binding
SLINC_RS11665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLINC_RS11675	COG1595	DNA-templated transcription, initiation
SLINC_RS11685	COG2171	N-acyltransferase activity
SLINC_RS11690	COG3226	Transcriptional regulator
SLINC_RS11695	COG2076	Multidrug Resistance protein
SLINC_RS11705	COG2151	metal-sulfur cluster biosynthetic enzyme
SLINC_RS11710	COG0822	iron-sulfur transferase activity
SLINC_RS11715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLINC_RS11720	COG0396	ATPase activity
SLINC_RS11730	COG0719	Fe-S assembly protein
SLINC_RS11745	COG2746	aminoglycoside 3-N-acetyltransferase activity
SLINC_RS11760	COG3903	Transcriptional regulator
SLINC_RS11760	COG3629	intracellular signal transduction
SLINC_RS11785	COG0109	protoheme IX farnesyltransferase activity
SLINC_RS11795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLINC_RS11810	COG0363	glucosamine-6-phosphate deaminase activity
SLINC_RS11815	COG0166	Belongs to the GPI family
SLINC_RS11830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SLINC_RS11835	COG0149	triose-phosphate isomerase activity
SLINC_RS11840	COG0126	phosphoglycerate kinase activity
SLINC_RS11845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SLINC_RS11855	COG1481	regulation of sporulation
SLINC_RS11860	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLINC_RS11865	COG1660	Displays ATPase and GTPase activities
SLINC_RS11870	COG0322	excinuclease ABC activity
SLINC_RS11875	COG2197	response regulator
SLINC_RS11880	COG4585	Histidine kinase
SLINC_RS11890	COG2197	response regulator
SLINC_RS11910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLINC_RS11925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLINC_RS11930	COG0765	amino acid transport
SLINC_RS11940	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SLINC_RS11945	COG1619	proteins homologs of microcin C7 resistance protein MccF
SLINC_RS11950	COG0477	Major facilitator Superfamily
SLINC_RS11955	COG0387	Pfam Sodium calcium exchanger
SLINC_RS11980	COG0556	nucleotide-excision repair
SLINC_RS11990	COG0584	glycerophosphoryl diester phosphodiesterase
SLINC_RS11995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLINC_RS12000	COG1063	alcohol dehydrogenase
SLINC_RS12010	COG2313	pseudouridylate synthase activity
SLINC_RS12015	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SLINC_RS12015	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SLINC_RS12020	COG2226	methyltransferase
SLINC_RS12025	COG0598	Magnesium transport protein CorA
SLINC_RS12055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS12060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS12100	COG1132	(ABC) transporter
SLINC_RS12110	COG0402	S-adenosylhomocysteine deaminase activity
SLINC_RS12150	COG1953	Uracil, thiamine, allantoin
SLINC_RS12155	COG1802	Transcriptional regulator
SLINC_RS12195	COG0237	dephospho-CoA kinase activity
SLINC_RS12210	COG2226	methyltransferase
SLINC_RS12215	COG1643	Atp-dependent helicase
SLINC_RS12250	COG2050	protein possibly involved in aromatic compounds catabolism
SLINC_RS12310	COG0737	Belongs to the 5'-nucleotidase family
SLINC_RS12335	COG1605	Chorismate mutase
SLINC_RS12335	COG0287	Prephenate dehydrogenase
SLINC_RS12365	COG1024	Enoyl-CoA hydratase
SLINC_RS12385	COG0183	Belongs to the thiolase family
SLINC_RS12390	COG1309	transcriptional regulator
SLINC_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS12400	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS12405	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS12410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLINC_RS12415	COG2304	oxidoreductase activity
SLINC_RS12425	COG0069	glutamate synthase activity
SLINC_RS12425	COG0067	glutamate synthase
SLINC_RS12425	COG0070	glutamate synthase
SLINC_RS12435	COG1397	ADP-ribosylglycohydrolase
SLINC_RS12455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLINC_RS12460	COG2301	Belongs to the HpcH HpaI aldolase family
SLINC_RS12465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SLINC_RS12475	COG0159	tryptophan synthase activity
SLINC_RS12480	COG0133	tryptophan synthase activity
SLINC_RS12485	COG0134	indole-3-glycerol-phosphate synthase activity
SLINC_RS12505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SLINC_RS12510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SLINC_RS12530	COG0107	imidazoleglycerol-phosphate synthase activity
SLINC_RS12535	COG0251	oxidation-reduction process
SLINC_RS12540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SLINC_RS12545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SLINC_RS12550	COG0131	Imidazoleglycerol-phosphate dehydratase
SLINC_RS12555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLINC_RS12560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SLINC_RS12600	COG1432	Conserved Protein
SLINC_RS12605	COG0587	DNA-directed DNA polymerase activity
SLINC_RS12660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SLINC_RS12670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SLINC_RS12675	COG3599	regulation of cell shape
SLINC_RS12685	COG1799	cell septum assembly
SLINC_RS12695	COG1496	oxidoreductase activity
SLINC_RS12700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SLINC_RS12705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SLINC_RS12710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SLINC_RS12720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLINC_RS12725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLINC_RS12735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SLINC_RS12740	COG0768	penicillin binding
SLINC_RS12750	COG0275	rRNA processing
SLINC_RS12760	COG0714	Associated with various cellular activities
SLINC_RS12780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLINC_RS12790	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SLINC_RS12800	COG1309	transcriptional regulator
SLINC_RS12820	COG0352	thiamine-phosphate diphosphorylase activity
SLINC_RS12840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS12840	COG2022	thiamine diphosphate biosynthetic process
SLINC_RS12850	COG2022	thiamine diphosphate biosynthetic process
SLINC_RS12855	COG2815	serine threonine protein kinase
SLINC_RS12855	COG0515	serine threonine protein kinase
SLINC_RS12860	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SLINC_RS12865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLINC_RS12870	COG2193	ferroxidase activity
SLINC_RS12875	COG0243	molybdopterin cofactor binding
SLINC_RS12880	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SLINC_RS12890	COG0205	6-phosphofructokinase activity
SLINC_RS12895	COG2197	response regulator
SLINC_RS12900	COG4585	Histidine kinase
SLINC_RS12925	COG1940	carbohydrate kinase activity
SLINC_RS12935	COG0003	Pfam Anion-transporting ATPase
SLINC_RS12950	COG1022	Amp-dependent synthetase and ligase
SLINC_RS13010	COG5002	protein histidine kinase activity
SLINC_RS13015	COG0745	RESPONSE REGULATOR receiver
SLINC_RS13025	COG1929	Belongs to the glycerate kinase type-1 family
SLINC_RS13030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLINC_RS13035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SLINC_RS13040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLINC_RS13045	COG0723	plastoquinol--plastocyanin reductase activity
SLINC_RS13050	COG2010	Cytochrome c
SLINC_RS13055	COG1845	cytochrome c oxidase, subunit III
SLINC_RS13065	COG1376	ErfK ybiS ycfS ynhG family protein
SLINC_RS13075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SLINC_RS13080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SLINC_RS13090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLINC_RS13110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SLINC_RS13115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLINC_RS13115	COG0515	serine threonine protein kinase
SLINC_RS13120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SLINC_RS13125	COG2197	response regulator
SLINC_RS13130	COG4585	Histidine kinase
SLINC_RS13170	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLINC_RS13185	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SLINC_RS13215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SLINC_RS13220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SLINC_RS13225	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLINC_RS13240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLINC_RS13280	COG1090	epimerase
SLINC_RS13295	COG0321	lipoyl(octanoyl) transferase activity
SLINC_RS13300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SLINC_RS13320	COG0174	glutamine synthetase
SLINC_RS13330	COG0501	Belongs to the peptidase M48B family
SLINC_RS13375	COG0745	RESPONSE REGULATOR receiver
SLINC_RS13385	COG4585	Histidine kinase
SLINC_RS13390	COG2197	response regulator
SLINC_RS13415	COG1309	transcriptional regulator
SLINC_RS13450	COG0366	Alpha amylase catalytic
SLINC_RS13455	COG3833	ABC-type maltose transport systems, permease component
SLINC_RS13460	COG1175	transmembrane transport
SLINC_RS13470	COG1609	Transcriptional regulator
SLINC_RS13480	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SLINC_RS13505	COG0174	glutamine synthetase
SLINC_RS13530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SLINC_RS13530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLINC_RS13535	COG0574	Belongs to the PEP-utilizing enzyme family
SLINC_RS13535	COG3848	Pyruvate phosphate dikinase
SLINC_RS13565	COG1309	transcriptional regulator
SLINC_RS13570	COG0477	Major facilitator Superfamily
SLINC_RS13575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SLINC_RS13600	COG1994	Peptidase M50
SLINC_RS13645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS13650	COG1120	ATPase activity
SLINC_RS13660	COG2837	iron assimilation
SLINC_RS13665	COG0672	)-iron permease
SLINC_RS13680	COG0584	glycerophosphoryl diester phosphodiesterase
SLINC_RS13695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS13700	COG2814	Major facilitator Superfamily
SLINC_RS13710	COG3540	Alkaline phosphatase
SLINC_RS13730	COG2259	Doxx family
SLINC_RS13750	COG0395	ABC-type sugar transport system, permease component
SLINC_RS13755	COG1175	transmembrane transport
SLINC_RS13840	COG0557	exoribonuclease II activity
SLINC_RS13845	COG3022	response to hydroperoxide
SLINC_RS13850	COG0800	Aldolase
SLINC_RS13865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SLINC_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS13885	COG2030	dehydratase
SLINC_RS13890	COG4585	Histidine kinase
SLINC_RS13895	COG2197	response regulator
SLINC_RS13915	COG0860	N-Acetylmuramoyl-L-alanine amidase
SLINC_RS13925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS13960	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS13965	COG1309	transcriptional regulator
SLINC_RS14005	COG3845	ABC transporter
SLINC_RS14020	COG3619	membrane
SLINC_RS14035	COG0640	Transcriptional regulator
SLINC_RS14055	COG0183	Belongs to the thiolase family
SLINC_RS14060	COG2124	cytochrome p450
SLINC_RS14075	COG4122	O-methyltransferase activity
SLINC_RS14150	COG2259	Doxx family
SLINC_RS14175	COG2814	Major facilitator Superfamily
SLINC_RS14185	COG2318	DinB family
SLINC_RS14195	COG0596	Alpha beta hydrolase
SLINC_RS14235	COG0586	Pfam SNARE associated Golgi protein
SLINC_RS14245	COG1358	cellular component organization or biogenesis
SLINC_RS14290	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLINC_RS14295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLINC_RS14305	COG0477	Major facilitator Superfamily
SLINC_RS14310	COG1309	transcriptional regulator
SLINC_RS14325	COG0667	Aldo Keto reductase
SLINC_RS14330	COG0789	Transcriptional regulator
SLINC_RS14345	COG1741	Belongs to the pirin family
SLINC_RS14360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLINC_RS14365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLINC_RS14370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLINC_RS14435	COG2130	NADP-dependent
SLINC_RS14455	COG4948	Mandelate Racemase Muconate Lactonizing
SLINC_RS14475	COG1129	ABC transporter
SLINC_RS14480	COG4214	carbohydrate transport
SLINC_RS14495	COG3940	Belongs to the glycosyl hydrolase 43 family
SLINC_RS14500	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS14565	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS14570	COG0395	ABC-type sugar transport system, permease component
SLINC_RS14575	COG1175	transmembrane transport
SLINC_RS14605	COG3386	PFAM SMP-30 Gluconolaconase
SLINC_RS14610	COG1414	Transcriptional regulator
SLINC_RS14640	COG4981	capsule polysaccharide biosynthetic process
SLINC_RS14685	COG2186	Transcriptional regulator
SLINC_RS14695	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS14700	COG0825	malonyl-CoA metabolic process
SLINC_RS14700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SLINC_RS14725	COG1077	Cell shape determining protein MreB Mrl
SLINC_RS14760	COG3903	Transcriptional regulator
SLINC_RS14760	COG3629	intracellular signal transduction
SLINC_RS14790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS14815	COG0515	serine threonine protein kinase
SLINC_RS14815	COG2815	serine threonine protein kinase
SLINC_RS14845	COG2197	response regulator
SLINC_RS14850	COG4585	Histidine kinase
SLINC_RS14855	COG1132	(ABC) transporter
SLINC_RS14890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS14900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS14905	COG1116	anion transmembrane transporter activity
SLINC_RS14915	COG0745	RESPONSE REGULATOR receiver
SLINC_RS14920	COG2205	protein histidine kinase activity
SLINC_RS14925	COG2409	Drug exporters of the RND superfamily
SLINC_RS14965	COG1070	Carbohydrate kinase
SLINC_RS14980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLINC_RS14985	COG0358	DNA primase activity
SLINC_RS14995	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SLINC_RS15005	COG2949	membrane
SLINC_RS15015	COG0243	molybdopterin cofactor binding
SLINC_RS15030	COG2072	flavoprotein involved in K transport
SLINC_RS15060	COG1733	regulation of RNA biosynthetic process
SLINC_RS15080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLINC_RS15085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLINC_RS15085	COG2146	nitrite reductase [NAD(P)H] activity
SLINC_RS15095	COG1309	transcriptional regulator
SLINC_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS15115	COG0659	secondary active sulfate transmembrane transporter activity
SLINC_RS15125	COG0745	RESPONSE REGULATOR receiver
SLINC_RS15145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLINC_RS15145	COG0574	Belongs to the PEP-utilizing enzyme family
SLINC_RS15150	COG1940	carbohydrate kinase activity
SLINC_RS15150	COG1846	Transcriptional regulator
SLINC_RS15155	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SLINC_RS15180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLINC_RS15205	COG0667	Aldo Keto reductase
SLINC_RS15210	COG1280	lysine exporter protein (LysE YggA)
SLINC_RS15215	COG0423	glycine-tRNA ligase activity
SLINC_RS15220	COG0803	Belongs to the bacterial solute-binding protein 9 family
SLINC_RS15220	COG3443	Belongs to the bacterial solute-binding protein 9 family
SLINC_RS15225	COG1121	(ABC) transporter
SLINC_RS15230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLINC_RS15240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLINC_RS15245	COG1381	Involved in DNA repair and RecF pathway recombination
SLINC_RS15290	COG1595	DNA-templated transcription, initiation
SLINC_RS15305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLINC_RS15315	COG2197	response regulator
SLINC_RS15320	COG4585	Histidine kinase
SLINC_RS15325	COG2409	Drug exporters of the RND superfamily
SLINC_RS15335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLINC_RS15350	COG2723	6-phospho-beta-galactosidase activity
SLINC_RS15370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SLINC_RS15395	COG2315	Protein conserved in bacteria
SLINC_RS15405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SLINC_RS15420	COG4948	Mandelate Racemase Muconate Lactonizing
SLINC_RS15425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLINC_RS15430	COG1414	Transcriptional regulator
SLINC_RS15435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLINC_RS15440	COG1234	tRNA 3'-trailer cleavage
SLINC_RS15445	COG0537	adenosine 5'-monophosphoramidase activity
SLINC_RS15450	COG4946	Tricorn protease homolog
SLINC_RS15450	COG0793	Belongs to the peptidase S41A family
SLINC_RS15480	COG0484	heat shock protein binding
SLINC_RS15485	COG1420	regulation of RNA biosynthetic process
SLINC_RS15525	COG0481	GTPase activity
SLINC_RS15530	COG0268	Binds directly to 16S ribosomal RNA
SLINC_RS15550	COG2353	YceI-like domain
SLINC_RS15555	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SLINC_RS15560	COG0658	competence protein
SLINC_RS15560	COG2333	competence protein COMEC
SLINC_RS15565	COG1555	photosystem II stabilization
SLINC_RS15565	COG1596	polysaccharide export
SLINC_RS15570	COG1307	EDD domain protein, DegV family
SLINC_RS15580	COG0495	leucyl-tRNA aminoacylation
SLINC_RS15590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLINC_RS15605	COG0477	Major facilitator Superfamily
SLINC_RS15620	COG0588	phosphoglycerate mutase activity
SLINC_RS15625	COG0799	negative regulation of ribosome biogenesis
SLINC_RS15635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SLINC_RS15640	COG0501	Belongs to the peptidase M48B family
SLINC_RS15655	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SLINC_RS15665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SLINC_RS15675	COG1216	Glycosyl transferase, family 2
SLINC_RS15675	COG1442	glycosyl transferase family 8
SLINC_RS15690	COG3540	Alkaline phosphatase
SLINC_RS15700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SLINC_RS15705	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SLINC_RS15710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SLINC_RS15740	COG1530	ribonuclease E activity
SLINC_RS15760	COG2195	Cleaves the N-terminal amino acid of tripeptides
SLINC_RS15765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SLINC_RS15805	COG0772	Belongs to the SEDS family
SLINC_RS15810	COG0768	penicillin binding
SLINC_RS15825	COG1077	Cell shape determining protein MreB Mrl
SLINC_RS15830	COG0105	UTP biosynthetic process
SLINC_RS15840	COG0285	dihydrofolate synthase activity
SLINC_RS15845	COG0525	valine-tRNA ligase activity
SLINC_RS15855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SLINC_RS15860	COG0740	serine-type endopeptidase activity
SLINC_RS15865	COG0740	serine-type endopeptidase activity
SLINC_RS15870	COG0544	peptidyl-prolyl cis-trans isomerase activity
SLINC_RS15890	COG3594	Acyltransferase
SLINC_RS15905	COG1136	(ABC) transporter
SLINC_RS15905	COG0577	efflux transmembrane transporter activity
SLINC_RS15915	COG4552	Acetyltransferase involved in intracellular survival and related
SLINC_RS15925	COG0698	ribose 5-phosphate isomerase
SLINC_RS15930	COG1113	amino acid transport
SLINC_RS15935	COG0515	serine threonine protein kinase
SLINC_RS15955	COG1113	amino acid transport
SLINC_RS15970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SLINC_RS15980	COG0588	phosphoglycerate mutase activity
SLINC_RS15985	COG1070	Carbohydrate kinase
SLINC_RS16010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SLINC_RS16090	COG0697	spore germination
SLINC_RS16095	COG1846	Transcriptional regulator
SLINC_RS16100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLINC_RS16125	COG1595	DNA-templated transcription, initiation
SLINC_RS16135	COG1131	(ABC) transporter
SLINC_RS16155	COG0668	transmembrane transport
SLINC_RS16165	COG1653	transport
SLINC_RS16170	COG1175	transmembrane transport
SLINC_RS16175	COG0395	ABC-type sugar transport system, permease component
SLINC_RS16180	COG1486	melibiose metabolic process
SLINC_RS16245	COG1136	(ABC) transporter
SLINC_RS16245	COG0577	efflux transmembrane transporter activity
SLINC_RS16270	COG0515	serine threonine protein kinase
SLINC_RS16270	COG2815	serine threonine protein kinase
SLINC_RS16280	COG1278	Cold shock
SLINC_RS16295	COG0629	single-stranded DNA binding
SLINC_RS16340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLINC_RS16395	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS16420	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS16480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLINC_RS16510	COG3962	Belongs to the TPP enzyme family
SLINC_RS16515	COG3718	enzyme involved in inositol metabolism
SLINC_RS16525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLINC_RS16555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SLINC_RS16575	COG1129	ABC transporter
SLINC_RS16585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLINC_RS16590	COG1869	D-ribose catabolic process
SLINC_RS16610	COG0673	inositol 2-dehydrogenase activity
SLINC_RS16615	COG1609	Transcriptional regulator
SLINC_RS16625	COG3896	Chloramphenicol phosphotransferase-like protein
SLINC_RS16645	COG0456	acetyltransferase
SLINC_RS16645	COG1846	Transcriptional regulator
SLINC_RS16665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SLINC_RS16670	COG1472	Belongs to the glycosyl hydrolase 3 family
SLINC_RS16705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLINC_RS16710	COG2356	endonuclease I
SLINC_RS16715	COG0028	Belongs to the TPP enzyme family
SLINC_RS16725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLINC_RS16740	COG1946	Acyl-CoA thioesterase
SLINC_RS16750	COG1309	transcriptional regulator
SLINC_RS16755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLINC_RS16770	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS16790	COG3409	Peptidoglycan-binding domain 1 protein
SLINC_RS16820	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLINC_RS16850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLINC_RS16860	COG0589	response to stress
SLINC_RS16870	COG4977	sequence-specific DNA binding
SLINC_RS16875	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SLINC_RS16910	COG0395	ABC-type sugar transport system, permease component
SLINC_RS16920	COG5002	protein histidine kinase activity
SLINC_RS16925	COG0745	RESPONSE REGULATOR receiver
SLINC_RS16950	COG0406	alpha-ribazole phosphatase activity
SLINC_RS17000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS17035	COG0765	amino acid transport
SLINC_RS17040	COG0765	amino acid transport
SLINC_RS17045	COG1126	abc transporter atp-binding protein
SLINC_RS17060	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS17070	COG3397	chitin binding
SLINC_RS17090	COG2186	Transcriptional regulator
SLINC_RS17135	COG1940	carbohydrate kinase activity
SLINC_RS17140	COG0673	inositol 2-dehydrogenase activity
SLINC_RS17145	COG4702	Belongs to the UPF0303 family
SLINC_RS17160	COG0706	membrane insertase activity
SLINC_RS17255	COG0071	Belongs to the small heat shock protein (HSP20) family
SLINC_RS17285	COG2733	membrane
SLINC_RS17300	COG4555	ABC transporter
SLINC_RS17315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLINC_RS17320	COG2076	Multidrug Resistance protein
SLINC_RS17355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SLINC_RS17365	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SLINC_RS17370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SLINC_RS17375	COG1263	PTS System
SLINC_RS17380	COG1263	PTS System
SLINC_RS17385	COG1234	tRNA 3'-trailer cleavage
SLINC_RS17415	COG1113	amino acid transport
SLINC_RS17425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SLINC_RS17435	COG1335	isochorismatase
SLINC_RS17470	COG0277	FAD linked oxidase domain protein
SLINC_RS17495	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SLINC_RS17505	COG1174	glycine betaine transport
SLINC_RS17515	COG1174	glycine betaine transport
SLINC_RS17545	COG3654	unkown
SLINC_RS17575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLINC_RS17590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLINC_RS17595	COG0395	ABC-type sugar transport system, permease component
SLINC_RS17600	COG1175	transmembrane transport
SLINC_RS17615	COG1678	Uncharacterized ACR, COG1678
SLINC_RS17620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLINC_RS17625	COG0776	regulation of translation
SLINC_RS17635	COG3973	AAA domain
SLINC_RS17665	COG2223	nitrite transmembrane transporter activity
SLINC_RS17685	COG0583	DNA-binding transcription factor activity
SLINC_RS17700	COG4209	transmembrane transport
SLINC_RS17705	COG0395	ABC-type sugar transport system, permease component
SLINC_RS17710	COG1501	Belongs to the glycosyl hydrolase 31 family
SLINC_RS17720	COG1472	Belongs to the glycosyl hydrolase 3 family
SLINC_RS17735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SLINC_RS17740	COG0793	Belongs to the peptidase S41A family
SLINC_RS17750	COG2884	Cell division ATP-binding protein ftsE
SLINC_RS17765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SLINC_RS17770	COG0515	serine threonine protein kinase
SLINC_RS17775	COG0515	serine threonine protein kinase
SLINC_RS17785	COG1653	transport
SLINC_RS17790	COG1175	transmembrane transport
SLINC_RS17795	COG0395	ABC-type sugar transport system, permease component
SLINC_RS17800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLINC_RS17805	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLINC_RS17810	COG1216	Glycosyl transferase, family 2
SLINC_RS17825	COG1764	response to oxidative stress
SLINC_RS17830	COG1846	Transcriptional regulator
SLINC_RS17860	COG1388	LysM domain
SLINC_RS17860	COG1134	teichoic acid transport
SLINC_RS17890	COG0653	protein targeting
SLINC_RS17900	COG3214	Protein conserved in bacteria
SLINC_RS17905	COG2197	response regulator
SLINC_RS17910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SLINC_RS17920	COG0823	Involved in the tonB-independent uptake of proteins
SLINC_RS17925	COG5002	protein histidine kinase activity
SLINC_RS17930	COG0745	RESPONSE REGULATOR receiver
SLINC_RS17935	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SLINC_RS17955	COG0714	Associated with various cellular activities
SLINC_RS18000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SLINC_RS18005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLINC_RS18005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SLINC_RS18005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SLINC_RS18020	COG1482	cell wall glycoprotein biosynthetic process
SLINC_RS18030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLINC_RS18035	COG1620	l-lactate permease
SLINC_RS18070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLINC_RS18075	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SLINC_RS18075	COG0778	Nitroreductase
SLINC_RS18100	COG1316	TRANSCRIPTIONal
SLINC_RS18110	COG1316	TRANSCRIPTIONal
SLINC_RS18115	COG1316	TRANSCRIPTIONal
SLINC_RS18120	COG0463	Glycosyl transferase, family 2
SLINC_RS18125	COG1316	TRANSCRIPTIONal
SLINC_RS18135	COG1316	TRANSCRIPTIONal
SLINC_RS18160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLINC_RS18170	COG1276	copper resistance
SLINC_RS18210	COG0745	RESPONSE REGULATOR receiver
SLINC_RS18220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SLINC_RS18235	COG2205	protein histidine kinase activity
SLINC_RS18240	COG0745	RESPONSE REGULATOR receiver
SLINC_RS18245	COG3104	oligopeptide transport
SLINC_RS18270	COG1366	Belongs to the anti-sigma-factor antagonist family
SLINC_RS18275	COG1191	sigma factor activity
SLINC_RS18305	COG1228	amidohydrolase
SLINC_RS18315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLINC_RS18320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SLINC_RS18370	COG1174	glycine betaine transport
SLINC_RS18375	COG1174	glycine betaine transport
SLINC_RS18395	COG2755	lipolytic protein G-D-S-L family
SLINC_RS18400	COG0183	Belongs to the thiolase family
SLINC_RS18435	COG1136	(ABC) transporter
SLINC_RS18440	COG0577	efflux transmembrane transporter activity
SLINC_RS18445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLINC_RS18450	COG1252	NADH dehydrogenase
SLINC_RS18470	COG0148	phosphopyruvate hydratase activity
SLINC_RS18480	COG1652	LysM domain
SLINC_RS18485	COG2124	cytochrome p450
SLINC_RS18530	COG0577	efflux transmembrane transporter activity
SLINC_RS18535	COG1136	(ABC) transporter
SLINC_RS18540	COG0477	Major facilitator Superfamily
SLINC_RS18565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLINC_RS18595	COG4585	Histidine kinase
SLINC_RS18610	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SLINC_RS18615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLINC_RS18620	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SLINC_RS18625	COG0193	aminoacyl-tRNA hydrolase activity
SLINC_RS18640	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SLINC_RS18650	COG1309	transcriptional regulator
SLINC_RS18665	COG4106	trans-aconitate 2-methyltransferase activity
SLINC_RS18675	COG2197	response regulator
SLINC_RS18710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SLINC_RS18750	COG0488	(ABC) transporter
SLINC_RS18755	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SLINC_RS18760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SLINC_RS18765	COG3584	3D domain protein
SLINC_RS18765	COG3583	domain protein
SLINC_RS18770	COG0084	hydrolase, TatD family'
SLINC_RS18810	COG0310	cobalt ion transport
SLINC_RS18820	COG1122	ATPase activity
SLINC_RS18825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS18845	COG0442	prolyl-tRNA aminoacylation
SLINC_RS18860	COG0456	acetyltransferase
SLINC_RS18875	COG2409	Drug exporters of the RND superfamily
SLINC_RS18885	COG4946	Tricorn protease homolog
SLINC_RS18885	COG0793	Belongs to the peptidase S41A family
SLINC_RS18895	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS18900	COG2267	carboxylic ester hydrolase activity
SLINC_RS18905	COG2072	flavoprotein involved in K transport
SLINC_RS18920	COG0708	Exodeoxyribonuclease III
SLINC_RS18925	COG0454	-acetyltransferase
SLINC_RS18930	COG2197	response regulator
SLINC_RS18935	COG4585	Histidine kinase
SLINC_RS18940	COG0577	efflux transmembrane transporter activity
SLINC_RS18940	COG1136	(ABC) transporter
SLINC_RS18945	COG0577	efflux transmembrane transporter activity
SLINC_RS18965	COG0521	Mo-molybdopterin cofactor biosynthetic process
SLINC_RS18965	COG0315	cyclic pyranopterin monophosphate synthase activity
SLINC_RS18970	COG0315	cyclic pyranopterin monophosphate synthase activity
SLINC_RS18980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLINC_RS18985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SLINC_RS19010	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SLINC_RS19020	COG1970	mechanosensitive ion channel activity
SLINC_RS19030	COG3191	aminopeptidase activity
SLINC_RS19035	COG1376	ErfK ybiS ycfS ynhG family protein
SLINC_RS19060	COG1349	DNA-binding transcription factor activity
SLINC_RS19065	COG0477	Major facilitator Superfamily
SLINC_RS19075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLINC_RS19080	COG3384	dioxygenase
SLINC_RS19085	COG1846	Transcriptional regulator
SLINC_RS19105	COG1414	Transcriptional regulator
SLINC_RS19115	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS19115	COG1024	Enoyl-CoA hydratase
SLINC_RS19140	COG0477	Major facilitator Superfamily
SLINC_RS19155	COG1309	transcriptional regulator
SLINC_RS19160	COG1621	beta-fructofuranosidase activity
SLINC_RS19170	COG0596	Alpha beta hydrolase
SLINC_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS19235	COG3852	Histidine kinase
SLINC_RS19240	COG0492	ferredoxin-NADP+ reductase activity
SLINC_RS19295	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS19300	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS19310	COG1879	ABC-type sugar transport system periplasmic component
SLINC_RS19315	COG1132	(ABC) transporter
SLINC_RS19320	COG1132	(ABC) transporter
SLINC_RS19320	COG2375	cellular response to nickel ion
SLINC_RS19330	COG2197	response regulator
SLINC_RS19335	COG4585	Histidine kinase
SLINC_RS19365	COG3629	intracellular signal transduction
SLINC_RS19365	COG3903	Transcriptional regulator
SLINC_RS19380	COG0386	Belongs to the glutathione peroxidase family
SLINC_RS19405	COG1686	Belongs to the peptidase S11 family
SLINC_RS19430	COG1404	Belongs to the peptidase S8 family
SLINC_RS19455	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLINC_RS19525	COG0640	Transcriptional regulator
SLINC_RS19550	COG2267	carboxylic ester hydrolase activity
SLINC_RS19555	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS19560	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SLINC_RS19585	COG2197	response regulator
SLINC_RS19600	COG3629	intracellular signal transduction
SLINC_RS19600	COG3903	Transcriptional regulator
SLINC_RS19610	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS19625	COG1024	Enoyl-CoA hydratase
SLINC_RS19630	COG0596	Alpha beta hydrolase
SLINC_RS19640	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLINC_RS19640	COG0515	serine threonine protein kinase
SLINC_RS19650	COG1309	transcriptional regulator
SLINC_RS19655	COG1522	sequence-specific DNA binding
SLINC_RS19660	COG1280	lysine exporter protein (LysE YggA)
SLINC_RS19670	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS19685	COG0259	pyridoxamine-phosphate oxidase activity
SLINC_RS19715	COG2072	flavoprotein involved in K transport
SLINC_RS19725	COG1024	Enoyl-CoA hydratase
SLINC_RS19755	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS19760	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS19775	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS19780	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS19805	COG1595	DNA-templated transcription, initiation
SLINC_RS19845	COG1131	(ABC) transporter
SLINC_RS19855	COG2945	thiolester hydrolase activity
SLINC_RS19855	COG0596	Alpha beta hydrolase
SLINC_RS19865	COG4821	SIS domain
SLINC_RS19890	COG0259	pyridoxamine-phosphate oxidase activity
SLINC_RS19905	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS19920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLINC_RS19975	COG2226	methyltransferase
SLINC_RS20010	COG0277	FAD linked oxidase domain protein
SLINC_RS20010	COG0247	lactate metabolic process
SLINC_RS20015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SLINC_RS20020	COG0596	Alpha beta hydrolase
SLINC_RS20025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SLINC_RS20070	COG0667	Aldo Keto reductase
SLINC_RS20100	COG2252	PERMEase
SLINC_RS20110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLINC_RS20150	COG2814	Major facilitator Superfamily
SLINC_RS20160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SLINC_RS20165	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLINC_RS20170	COG1278	Cold shock
SLINC_RS20190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SLINC_RS20205	COG1061	Type III restriction enzyme res subunit
SLINC_RS20215	COG3973	AAA domain
SLINC_RS20220	COG3142	Participates in the control of copper homeostasis
SLINC_RS20240	COG0326	Molecular chaperone. Has ATPase activity
SLINC_RS20265	COG1737	Transcriptional regulator
SLINC_RS20270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SLINC_RS20290	COG0667	Aldo Keto reductase
SLINC_RS20320	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS20320	COG2319	Wd-40 repeat
SLINC_RS20350	COG0459	protein refolding
SLINC_RS20370	COG0463	Glycosyl transferase, family 2
SLINC_RS20390	COG1653	transport
SLINC_RS20395	COG1940	carbohydrate kinase activity
SLINC_RS20400	COG1228	amidohydrolase
SLINC_RS20405	COG1105	Belongs to the carbohydrate kinase PfkB family
SLINC_RS20415	COG3300	MHYT domain
SLINC_RS20415	COG5001	Diguanylate cyclase
SLINC_RS20530	COG3842	ATPase activity
SLINC_RS20555	COG0215	cysteine-tRNA ligase activity
SLINC_RS20560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SLINC_RS20565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SLINC_RS20570	COG1329	Transcriptional regulator
SLINC_RS20615	COG1404	Belongs to the peptidase S8 family
SLINC_RS20650	COG0588	phosphoglycerate mutase activity
SLINC_RS20680	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS20725	COG0494	nUDIX hydrolase
SLINC_RS20740	COG2226	methyltransferase
SLINC_RS20755	COG4221	oxidoreductase activity
SLINC_RS20760	COG0300	oxidoreductase activity
SLINC_RS20775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SLINC_RS20785	COG3973	AAA domain
SLINC_RS20810	COG0546	phosphoglycolate phosphatase activity
SLINC_RS20815	COG2188	Transcriptional regulator
SLINC_RS20825	COG2188	Transcriptional regulator
SLINC_RS20835	COG4552	Acetyltransferase involved in intracellular survival and related
SLINC_RS20845	COG1490	D-aminoacyl-tRNA deacylase activity
SLINC_RS20850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLINC_RS20855	COG0735	belongs to the Fur family
SLINC_RS20860	COG3485	protocatechuate 3,4-dioxygenase
SLINC_RS20890	COG2897	thiosulfate sulfurtransferase activity
SLINC_RS20920	COG0745	RESPONSE REGULATOR receiver
SLINC_RS20925	COG1609	Transcriptional regulator
SLINC_RS20930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLINC_RS20940	COG0745	RESPONSE REGULATOR receiver
SLINC_RS20970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLINC_RS20980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS20990	COG1132	(ABC) transporter
SLINC_RS21000	COG0737	Belongs to the 5'-nucleotidase family
SLINC_RS21005	COG0456	acetyltransferase
SLINC_RS21035	COG1725	Transcriptional regulator
SLINC_RS21040	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SLINC_RS21055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SLINC_RS21065	COG0406	alpha-ribazole phosphatase activity
SLINC_RS21065	COG0494	nUDIX hydrolase
SLINC_RS21085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SLINC_RS21090	COG0306	phosphate transporter
SLINC_RS21100	COG1937	Protein conserved in bacteria
SLINC_RS21115	COG0277	FAD linked oxidase domain protein
SLINC_RS21120	COG0671	phosphoesterase, PA-phosphatase related
SLINC_RS21125	COG0741	lytic transglycosylase activity
SLINC_RS21125	COG0739	heme binding
SLINC_RS21125	COG1196	nuclear chromosome segregation
SLINC_RS21130	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLINC_RS21130	COG0515	serine threonine protein kinase
SLINC_RS21150	COG4221	oxidoreductase activity
SLINC_RS21200	COG4585	Histidine kinase
SLINC_RS21205	COG2197	response regulator
SLINC_RS21245	COG1252	NADH dehydrogenase
SLINC_RS21275	COG0579	oxidoreductase
SLINC_RS21280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SLINC_RS21310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SLINC_RS21310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SLINC_RS21320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLINC_RS21325	COG2197	response regulator
SLINC_RS21335	COG3409	Peptidoglycan-binding domain 1 protein
SLINC_RS21355	COG0475	glutathione-regulated potassium exporter activity
SLINC_RS21385	COG1278	Cold shock
SLINC_RS21405	COG0513	Belongs to the DEAD box helicase family
SLINC_RS21410	COG1278	Cold shock
SLINC_RS21445	COG0513	Belongs to the DEAD box helicase family
SLINC_RS21480	COG1643	Atp-dependent helicase
SLINC_RS21505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SLINC_RS21515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SLINC_RS21550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLINC_RS21555	COG0047	phosphoribosylformylglycinamidine synthase activity
SLINC_RS21560	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLINC_RS21595	COG2197	response regulator
SLINC_RS21605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SLINC_RS21620	COG0151	Belongs to the GarS family
SLINC_RS21695	COG2188	Transcriptional regulator
SLINC_RS21705	COG2188	Transcriptional regulator
SLINC_RS21765	COG0702	epimerase
SLINC_RS21780	COG0745	RESPONSE REGULATOR receiver
SLINC_RS21800	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS21800	COG2319	Wd-40 repeat
SLINC_RS21825	COG2409	Drug exporters of the RND superfamily
SLINC_RS21830	COG2197	response regulator
SLINC_RS21835	COG4585	Histidine kinase
SLINC_RS21855	COG2372	response to copper ion
SLINC_RS21855	COG1276	copper resistance
SLINC_RS21860	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS21880	COG2375	cellular response to nickel ion
SLINC_RS21880	COG1132	(ABC) transporter
SLINC_RS21900	COG0433	COG0433 Predicted ATPase
SLINC_RS21915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SLINC_RS21965	COG1191	sigma factor activity
SLINC_RS21970	COG1191	sigma factor activity
SLINC_RS21985	COG0477	Major facilitator Superfamily
SLINC_RS21990	COG2353	YceI-like domain
SLINC_RS22015	COG3467	pyridoxamine 5'-phosphate
SLINC_RS22025	COG0477	Major facilitator Superfamily
SLINC_RS22030	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLINC_RS22040	COG2205	protein histidine kinase activity
SLINC_RS22045	COG0745	RESPONSE REGULATOR receiver
SLINC_RS22055	COG1090	epimerase
SLINC_RS22060	COG1595	DNA-templated transcription, initiation
SLINC_RS22075	COG1846	Transcriptional regulator
SLINC_RS22125	COG1309	transcriptional regulator
SLINC_RS22130	COG2814	Major facilitator Superfamily
SLINC_RS22135	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS22145	COG1595	DNA-templated transcription, initiation
SLINC_RS22190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLINC_RS22205	COG0653	protein targeting
SLINC_RS22225	COG0006	proline dipeptidase activity
SLINC_RS22230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS22240	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SLINC_RS22275	COG2837	iron assimilation
SLINC_RS22290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SLINC_RS22295	COG0561	phosphatase activity
SLINC_RS22340	COG0789	Transcriptional regulator
SLINC_RS22345	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SLINC_RS22360	COG0561	phosphatase activity
SLINC_RS22375	COG4988	ABC transporter
SLINC_RS22380	COG1294	oxidase, subunit
SLINC_RS22385	COG1271	oxidase subunit
SLINC_RS22390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLINC_RS22395	COG1609	Transcriptional regulator
SLINC_RS22410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SLINC_RS22440	COG0662	Cupin 2, conserved barrel domain protein
SLINC_RS22445	COG1950	PFAM Membrane protein of
SLINC_RS22450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLINC_RS22455	COG0626	cystathionine gamma-synthase activity
SLINC_RS22485	COG2814	Major facilitator Superfamily
SLINC_RS22525	COG0305	Participates in initiation and elongation during chromosome replication
SLINC_RS22535	COG0359	binds to the 23S rRNA
SLINC_RS22540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLINC_RS22545	COG0629	single-stranded DNA binding
SLINC_RS22550	COG0360	Binds together with S18 to 16S ribosomal RNA
SLINC_RS22580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLINC_RS22600	COG0617	tRNA 3'-terminal CCA addition
SLINC_RS22615	COG0515	serine threonine protein kinase
SLINC_RS22615	COG2815	serine threonine protein kinase
SLINC_RS22620	COG1595	DNA-templated transcription, initiation
SLINC_RS22630	COG0492	ferredoxin-NADP+ reductase activity
SLINC_RS22635	COG3118	belongs to the thioredoxin family
SLINC_RS22650	COG1192	Involved in chromosome partitioning
SLINC_RS22655	COG0357	Ribosomal RNA small subunit methyltransferase G
SLINC_RS22665	COG0706	membrane insertase activity
SLINC_RS22670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SLINC_RS22685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SLINC_RS22690	COG0592	DNA-directed DNA polymerase activity
SLINC_RS22695	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SLINC_RS22700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SLINC_RS22705	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SLINC_RS22710	COG0187	DNA topoisomerase II activity
SLINC_RS22715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLINC_RS22740	COG0515	serine threonine protein kinase
SLINC_RS22765	COG0705	Rhomboid family
SLINC_RS22780	COG3764	Sortase (surface protein transpeptidase)
SLINC_RS22795	COG3764	Sortase (surface protein transpeptidase)
SLINC_RS22800	COG3764	Sortase (surface protein transpeptidase)
SLINC_RS22805	COG0515	serine threonine protein kinase
SLINC_RS22810	COG0768	penicillin binding
SLINC_RS22825	COG1716	ATPase activity
SLINC_RS22830	COG1716	ATPase activity
SLINC_RS22840	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SLINC_RS22845	COG1733	regulation of RNA biosynthetic process
SLINC_RS22860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SLINC_RS22890	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS22895	COG1309	transcriptional regulator
SLINC_RS22900	COG1522	sequence-specific DNA binding
SLINC_RS22930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLINC_RS22945	COG3321	synthase
SLINC_RS22945	COG0604	alcohol dehydrogenase
SLINC_RS22945	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS22960	COG0515	serine threonine protein kinase
SLINC_RS22965	COG0515	serine threonine protein kinase
SLINC_RS22990	COG0022	dehydrogenase e1 component
SLINC_RS22995	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLINC_RS23060	COG1362	aminopeptidase activity
SLINC_RS23065	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS23085	COG0477	Major facilitator Superfamily
SLINC_RS23090	COG1741	Belongs to the pirin family
SLINC_RS23110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SLINC_RS23135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLINC_RS23150	COG3866	Pectate lyase
SLINC_RS23180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLINC_RS23195	COG1289	transmembrane transporter activity
SLINC_RS23205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SLINC_RS23210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS23280	COG0701	Predicted permease
SLINC_RS23300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLINC_RS23305	COG1957	nucleoside hydrolase
SLINC_RS23335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS23385	COG0366	Alpha amylase catalytic
SLINC_RS23440	COG1278	Cold shock
SLINC_RS23465	COG4585	Histidine kinase
SLINC_RS23475	COG4213	ABC transporter substrate-binding protein
SLINC_RS23480	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS23485	COG0477	Major facilitator Superfamily
SLINC_RS23510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLINC_RS23520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLINC_RS23525	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS23540	COG0477	Major facilitator Superfamily
SLINC_RS23555	COG0135	phosphoribosylanthranilate isomerase activity
SLINC_RS23595	COG4948	Mandelate Racemase Muconate Lactonizing
SLINC_RS23635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS23640	COG1595	DNA-templated transcription, initiation
SLINC_RS23665	COG1609	Transcriptional regulator
SLINC_RS23675	COG0494	nUDIX hydrolase
SLINC_RS23715	COG4585	Histidine kinase
SLINC_RS23720	COG0586	Pfam SNARE associated Golgi protein
SLINC_RS23730	COG1309	transcriptional regulator
SLINC_RS23735	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS23760	COG0513	Belongs to the DEAD box helicase family
SLINC_RS23765	COG1278	Cold shock
SLINC_RS23780	COG0714	Associated with various cellular activities
SLINC_RS23815	COG3629	intracellular signal transduction
SLINC_RS23815	COG3903	Transcriptional regulator
SLINC_RS23850	COG1376	ErfK ybiS ycfS ynhG family protein
SLINC_RS23865	COG0745	RESPONSE REGULATOR receiver
SLINC_RS23870	COG2205	protein histidine kinase activity
SLINC_RS23905	COG1309	transcriptional regulator
SLINC_RS23910	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS23925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLINC_RS23930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SLINC_RS23935	COG2080	2 iron, 2 sulfur cluster binding
SLINC_RS23950	COG2197	response regulator
SLINC_RS23955	COG4585	Histidine kinase
SLINC_RS23970	COG4585	Histidine kinase
SLINC_RS24000	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SLINC_RS24030	COG2815	serine threonine protein kinase
SLINC_RS24030	COG0515	serine threonine protein kinase
SLINC_RS24055	COG3693	PFAM glycoside hydrolase, family 10
SLINC_RS24100	COG4591	ABC-type transport system involved in lipoprotein release permease component
SLINC_RS24100	COG1136	(ABC) transporter
SLINC_RS24180	COG0297	glycogen (starch) synthase activity
SLINC_RS24200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLINC_RS24285	COG0717	Belongs to the dCTP deaminase family
SLINC_RS24290	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SLINC_RS24325	COG2181	nitrate reductase activity
SLINC_RS24325	COG0247	lactate metabolic process
SLINC_RS24330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLINC_RS24335	COG0443	Heat shock 70 kDa protein
SLINC_RS24340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SLINC_RS24345	COG0484	heat shock protein binding
SLINC_RS24350	COG0789	Transcriptional regulator
SLINC_RS24380	COG4213	ABC transporter substrate-binding protein
SLINC_RS24385	COG1305	Transglutaminase-like
SLINC_RS24400	COG2311	Membrane
SLINC_RS24410	COG1131	(ABC) transporter
SLINC_RS24460	COG0542	response to heat
SLINC_RS24490	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SLINC_RS24505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SLINC_RS24510	COG0191	fructose-bisphosphate aldolase activity
SLINC_RS24515	COG0477	Major facilitator Superfamily
SLINC_RS24530	COG3844	kynureninase activity
SLINC_RS24550	COG4585	Histidine kinase
SLINC_RS24555	COG2197	response regulator
SLINC_RS24565	COG2197	response regulator
SLINC_RS24580	COG3559	Exporter of polyketide antibiotics
SLINC_RS24585	COG1131	(ABC) transporter
SLINC_RS24615	COG4303	Ethanolamine ammonia lyase large subunit
SLINC_RS24630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SLINC_RS24635	COG0737	Belongs to the 5'-nucleotidase family
SLINC_RS24655	COG1802	Transcriptional regulator
SLINC_RS24660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLINC_RS24665	COG0693	protein deglycase activity
SLINC_RS24690	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SLINC_RS24695	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SLINC_RS24750	COG2205	protein histidine kinase activity
SLINC_RS24755	COG0745	RESPONSE REGULATOR receiver
SLINC_RS24770	COG1595	DNA-templated transcription, initiation
SLINC_RS24800	COG0701	Predicted permease
SLINC_RS24815	COG2249	NAD(P)H dehydrogenase (quinone) activity
SLINC_RS24820	COG2815	serine threonine protein kinase
SLINC_RS24820	COG0515	serine threonine protein kinase
SLINC_RS24840	COG2319	Wd-40 repeat
SLINC_RS24840	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS24860	COG1309	transcriptional regulator
SLINC_RS24875	COG1408	metallophosphoesterase
SLINC_RS24915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLINC_RS24925	COG0003	Pfam Anion-transporting ATPase
SLINC_RS24945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLINC_RS24970	COG2267	carboxylic ester hydrolase activity
SLINC_RS24980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SLINC_RS24985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLINC_RS25045	COG1205	dead DEAH box helicase
SLINC_RS25045	COG1111	helicase
SLINC_RS25050	COG1366	Belongs to the anti-sigma-factor antagonist family
SLINC_RS25055	COG2172	sigma factor antagonist activity
SLINC_RS25060	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SLINC_RS25085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SLINC_RS25085	COG1754	DNA topoisomerase type I activity
SLINC_RS25090	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SLINC_RS25185	COG1733	regulation of RNA biosynthetic process
SLINC_RS25205	COG1136	(ABC) transporter
SLINC_RS25215	COG2197	response regulator
SLINC_RS25255	COG3629	intracellular signal transduction
SLINC_RS25255	COG3903	Transcriptional regulator
SLINC_RS25260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLINC_RS25260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLINC_RS25290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLINC_RS25295	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLINC_RS25300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLINC_RS25305	COG0254	rRNA binding
SLINC_RS25315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLINC_RS25335	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS25340	COG2318	DinB family
SLINC_RS25360	COG0076	glutamate decarboxylase activity
SLINC_RS25365	COG0789	Transcriptional regulator
SLINC_RS25370	COG0393	Putative heavy-metal-binding
SLINC_RS25375	COG0586	Pfam SNARE associated Golgi protein
SLINC_RS25385	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SLINC_RS25390	COG2027	D-alanyl-D-alanine carboxypeptidase
SLINC_RS25400	COG0037	tRNA processing
SLINC_RS25415	COG0302	gtp cyclohydrolase
SLINC_RS25430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SLINC_RS25470	COG0649	NAD binding
SLINC_RS25490	COG1660	Displays ATPase and GTPase activities
SLINC_RS25505	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SLINC_RS25515	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SLINC_RS25520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SLINC_RS25530	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SLINC_RS25550	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SLINC_RS25585	COG0739	heme binding
SLINC_RS25595	COG0477	Major facilitator Superfamily
SLINC_RS25610	COG2205	protein histidine kinase activity
SLINC_RS25615	COG0745	RESPONSE REGULATOR receiver
SLINC_RS25625	COG1595	DNA-templated transcription, initiation
SLINC_RS25630	COG1194	a g-specific adenine glycosylase
SLINC_RS25635	COG4585	Histidine kinase
SLINC_RS25655	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SLINC_RS25675	COG0248	Ppx GppA phosphatase
SLINC_RS25680	COG3537	Alpha-1,2-mannosidase
SLINC_RS25685	COG1082	Xylose isomerase domain protein TIM barrel
SLINC_RS25690	COG1309	transcriptional regulator
SLINC_RS25695	COG0129	dihydroxy-acid dehydratase activity
SLINC_RS25705	COG4991	sh3 domain protein
SLINC_RS25720	COG0842	Transport permease protein
SLINC_RS25720	COG1129	ABC transporter
SLINC_RS25730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SLINC_RS25735	COG0180	Tryptophanyl-tRNA synthetase
SLINC_RS25755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLINC_RS25765	COG0738	Major facilitator superfamily
SLINC_RS25770	COG0123	including yeast histone deacetylase and acetoin utilization protein
SLINC_RS25815	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SLINC_RS25820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SLINC_RS25825	COG0181	hydroxymethylbilane synthase activity
SLINC_RS25840	COG0113	porphobilinogen synthase activity
SLINC_RS25855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS25870	COG0018	arginyl-trna synthetase
SLINC_RS25875	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SLINC_RS25895	COG1690	Belongs to the RtcB family
SLINC_RS25920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS25940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLINC_RS25960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS25995	COG2175	clavaminate synthase activity
SLINC_RS26010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SLINC_RS26055	COG0477	Major facilitator Superfamily
SLINC_RS26095	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SLINC_RS26100	COG0406	alpha-ribazole phosphatase activity
SLINC_RS26110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLINC_RS26115	COG0785	Cytochrome C biogenesis protein
SLINC_RS26120	COG1333	cytochrome c biogenesis protein
SLINC_RS26125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SLINC_RS26150	COG0789	Transcriptional regulator
SLINC_RS26155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLINC_RS26165	COG0697	spore germination
SLINC_RS26170	COG0583	DNA-binding transcription factor activity
SLINC_RS26180	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SLINC_RS26195	COG0163	prenyltransferase activity
SLINC_RS26205	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLINC_RS26210	COG1573	uracil-dna glycosylase
SLINC_RS26235	COG1309	transcriptional regulator
SLINC_RS26245	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS26290	COG1053	succinate dehydrogenase
SLINC_RS26310	COG1396	sequence-specific DNA binding
SLINC_RS26315	COG1278	Cold shock
SLINC_RS26320	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLINC_RS26325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLINC_RS26325	COG0515	serine threonine protein kinase
SLINC_RS26335	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLINC_RS26345	COG3979	chitinase
SLINC_RS26350	COG2226	methyltransferase
SLINC_RS26380	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS26385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS26390	COG0649	NAD binding
SLINC_RS26400	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLINC_RS26405	COG1034	ATP synthesis coupled electron transport
SLINC_RS26410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLINC_RS26415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS26420	COG0839	Belongs to the complex I subunit 6 family
SLINC_RS26425	COG0713	ATP synthesis coupled electron transport
SLINC_RS26430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLINC_RS26440	COG1007	ATP synthesis coupled electron transport
SLINC_RS26470	COG1175	transmembrane transport
SLINC_RS26475	COG0395	ABC-type sugar transport system, permease component
SLINC_RS26485	COG0561	phosphatase activity
SLINC_RS26490	COG3953	SLT domain
SLINC_RS26490	COG5280	Phage tail tape measure protein TP901
SLINC_RS26500	COG3104	oligopeptide transport
SLINC_RS26505	COG0142	geranyltranstransferase activity
SLINC_RS26520	COG1131	(ABC) transporter
SLINC_RS26560	COG1733	regulation of RNA biosynthetic process
SLINC_RS26575	COG0702	epimerase
SLINC_RS26590	COG1013	pyruvate-flavodoxin oxidoreductase activity
SLINC_RS26595	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SLINC_RS26595	COG0674	pyruvate-flavodoxin oxidoreductase activity
SLINC_RS26615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS26620	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS26625	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS26630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLINC_RS26635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS26640	COG0839	Belongs to the complex I subunit 6 family
SLINC_RS26645	COG0713	ATP synthesis coupled electron transport
SLINC_RS26650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLINC_RS26655	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS26660	COG1007	ATP synthesis coupled electron transport
SLINC_RS26665	COG0501	Belongs to the peptidase M48B family
SLINC_RS26670	COG3304	Inner membrane component domain
SLINC_RS26685	COG2261	transglycosylase associated protein
SLINC_RS26690	COG1666	GTP binding
SLINC_RS26725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLINC_RS26730	COG2030	dehydratase
SLINC_RS26745	COG0477	Major facilitator Superfamily
SLINC_RS26750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SLINC_RS26760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLINC_RS26765	COG0436	Aminotransferase
SLINC_RS26785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SLINC_RS26790	COG0081	regulation of translation
SLINC_RS26805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SLINC_RS26810	COG0222	ribosome binding
SLINC_RS26815	COG0085	RNA polymerase activity
SLINC_RS26820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SLINC_RS26860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SLINC_RS26865	COG0049	tRNA binding
SLINC_RS26870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLINC_RS26875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLINC_RS26890	COG0051	transcription antitermination factor activity, RNA binding
SLINC_RS26895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SLINC_RS26900	COG0088	Forms part of the polypeptide exit tunnel
SLINC_RS26905	COG0089	rRNA binding
SLINC_RS26910	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SLINC_RS26915	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SLINC_RS26920	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SLINC_RS26925	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SLINC_RS26930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SLINC_RS26935	COG0255	Belongs to the universal ribosomal protein uL29 family
SLINC_RS26940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SLINC_RS26945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SLINC_RS26950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SLINC_RS26955	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SLINC_RS26960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLINC_RS26965	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SLINC_RS26970	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SLINC_RS26975	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SLINC_RS26980	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SLINC_RS26985	COG1841	ribosomal large subunit assembly
SLINC_RS26990	COG0200	Binds to the 23S rRNA
SLINC_RS27000	COG0563	adenylate kinase activity
SLINC_RS27010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SLINC_RS27015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SLINC_RS27020	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SLINC_RS27025	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SLINC_RS27030	COG0202	RNA polymerase activity
SLINC_RS27035	COG0203	ribosomal protein L17
SLINC_RS27040	COG0101	tRNA pseudouridine synthase activity
SLINC_RS27055	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SLINC_RS27060	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SLINC_RS27065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLINC_RS27075	COG1072	(Pantothenic acid kinase))
SLINC_RS27080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLINC_RS27130	COG0736	holo-[acyl-carrier-protein] synthase activity
SLINC_RS27145	COG0789	Transcriptional regulator
SLINC_RS27150	COG2814	Major facilitator Superfamily
SLINC_RS27170	COG0583	DNA-binding transcription factor activity
SLINC_RS27180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS27185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLINC_RS27190	COG1082	Xylose isomerase domain protein TIM barrel
SLINC_RS27205	COG1940	carbohydrate kinase activity
SLINC_RS27230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SLINC_RS27240	COG0802	atpase or kinase
SLINC_RS27260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SLINC_RS27280	COG1609	Transcriptional regulator
SLINC_RS27305	COG4941	Belongs to the sigma-70 factor family
SLINC_RS27315	COG0726	polysaccharide deacetylase
SLINC_RS27320	COG0726	polysaccharide deacetylase
SLINC_RS27325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SLINC_RS27330	COG0459	protein refolding
SLINC_RS27340	COG4221	oxidoreductase activity
SLINC_RS27350	COG0583	DNA-binding transcription factor activity
SLINC_RS27365	COG1595	DNA-templated transcription, initiation
SLINC_RS27375	COG0516	GMP reductase activity
SLINC_RS27390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SLINC_RS27405	COG0515	serine threonine protein kinase
SLINC_RS27405	COG2815	serine threonine protein kinase
SLINC_RS27410	COG0515	serine threonine protein kinase
SLINC_RS27415	COG0515	serine threonine protein kinase
SLINC_RS27420	COG0515	serine threonine protein kinase
SLINC_RS27425	COG0515	serine threonine protein kinase
SLINC_RS27430	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS27455	COG0519	Catalyzes the synthesis of GMP from XMP
SLINC_RS27455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SLINC_RS27500	COG2197	response regulator
SLINC_RS27505	COG0791	NLP P60 protein
SLINC_RS27530	COG0739	heme binding
SLINC_RS27540	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS27540	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS27555	COG0714	Associated with various cellular activities
SLINC_RS27560	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SLINC_RS27570	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SLINC_RS27585	COG0045	succinate-CoA ligase (ADP-forming) activity
SLINC_RS27615	COG0138	bifunctional purine biosynthesis protein purh
SLINC_RS27635	COG2815	serine threonine protein kinase
SLINC_RS27635	COG0515	serine threonine protein kinase
SLINC_RS27645	COG2815	serine threonine protein kinase
SLINC_RS27645	COG0515	serine threonine protein kinase
SLINC_RS27660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SLINC_RS27680	COG0039	L-malate dehydrogenase activity
SLINC_RS27710	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS27720	COG4175	Glycine betaine
SLINC_RS27720	COG0517	IMP dehydrogenase activity
SLINC_RS27725	COG4176	ABC-type proline glycine betaine transport system permease component
SLINC_RS27740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS27745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS27750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLINC_RS27770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLINC_RS27795	COG0180	Tryptophanyl-tRNA synthetase
SLINC_RS27815	COG0671	phosphoesterase, PA-phosphatase related
SLINC_RS27830	COG1295	ribonuclease BN
SLINC_RS27835	COG1686	Belongs to the peptidase S11 family
SLINC_RS27845	COG1408	metallophosphoesterase
SLINC_RS27865	COG2205	protein histidine kinase activity
SLINC_RS27870	COG0745	RESPONSE REGULATOR receiver
SLINC_RS27875	COG2409	Drug exporters of the RND superfamily
SLINC_RS27930	COG1053	succinate dehydrogenase
SLINC_RS27940	COG2009	succinate dehydrogenase
SLINC_RS27985	COG1595	DNA-templated transcription, initiation
SLINC_RS28000	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS28000	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS28020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SLINC_RS28050	COG0463	Glycosyl transferase, family 2
SLINC_RS28065	COG1216	Glycosyl transferase, family 2
SLINC_RS28080	COG2089	acid synthase
SLINC_RS28090	COG2226	methyltransferase
SLINC_RS28100	COG1473	amidohydrolase
SLINC_RS28100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLINC_RS28105	COG1744	ABC transporter substrate-binding protein PnrA-like
SLINC_RS28110	COG3845	ABC transporter
SLINC_RS28115	COG4603	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS28120	COG1079	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS28150	COG2814	Major facilitator Superfamily
SLINC_RS28155	COG0583	DNA-binding transcription factor activity
SLINC_RS28165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLINC_RS28190	COG2205	protein histidine kinase activity
SLINC_RS28195	COG0745	RESPONSE REGULATOR receiver
SLINC_RS28200	COG1595	DNA-templated transcription, initiation
SLINC_RS28205	COG0572	uridine kinase
SLINC_RS28220	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS28240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLINC_RS28270	COG4770	biotin carboxylase activity
SLINC_RS28280	COG0424	maF-like protein
SLINC_RS28285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLINC_RS28295	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLINC_RS28305	COG1024	Enoyl-CoA hydratase
SLINC_RS28315	COG2986	histidine ammonia-lyase
SLINC_RS28345	COG1136	(ABC) transporter
SLINC_RS28350	COG1404	Belongs to the peptidase S8 family
SLINC_RS28365	COG1064	alcohol dehydrogenase
SLINC_RS28370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS28375	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS28380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS28415	COG3835	regulator
SLINC_RS28425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLINC_RS28425	COG5549	protein import
SLINC_RS28430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLINC_RS28455	COG2255	four-way junction helicase activity
SLINC_RS28460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SLINC_RS28475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SLINC_RS28485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLINC_RS28500	COG2255	four-way junction helicase activity
SLINC_RS28505	COG1331	Highly conserved protein containing a thioredoxin domain
SLINC_RS28520	COG1215	transferase activity, transferring glycosyl groups
SLINC_RS28530	COG1309	transcriptional regulator
SLINC_RS28535	COG0477	Major facilitator Superfamily
SLINC_RS28545	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SLINC_RS28590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SLINC_RS28605	COG1414	Transcriptional regulator
SLINC_RS28610	COG0251	oxidation-reduction process
SLINC_RS28615	COG2610	gluconate transmembrane transporter activity
SLINC_RS28710	COG2045	Belongs to the ComB family
SLINC_RS28750	COG2894	cell division
SLINC_RS28780	COG4585	Histidine kinase
SLINC_RS28830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLINC_RS28835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SLINC_RS28840	COG0741	lytic transglycosylase activity
SLINC_RS28860	COG1136	(ABC) transporter
SLINC_RS28880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLINC_RS28925	COG0114	fumarate hydratase activity
SLINC_RS28930	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SLINC_RS28930	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SLINC_RS28955	COG0778	Nitroreductase
SLINC_RS28960	COG1722	exodeoxyribonuclease VII activity
SLINC_RS28965	COG1570	exodeoxyribonuclease VII activity
SLINC_RS28975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SLINC_RS28990	COG0012	GTP binding
SLINC_RS29005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLINC_RS29010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLINC_RS29015	COG1410	methionine synthase
SLINC_RS29015	COG0646	methionine synthase
SLINC_RS29060	COG1917	Cupin 2, conserved barrel domain protein
SLINC_RS29075	COG1672	PFAM Archaeal ATPase
SLINC_RS29075	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLINC_RS29085	COG0778	Nitroreductase
SLINC_RS29115	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SLINC_RS29120	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS29130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SLINC_RS29150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS29160	COG2197	response regulator
SLINC_RS29230	COG1053	succinate dehydrogenase
SLINC_RS29255	COG1217	gtp-binding protein TYPA
SLINC_RS29270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLINC_RS29280	COG4608	Belongs to the ABC transporter superfamily
SLINC_RS29290	COG4608	Belongs to the ABC transporter superfamily
SLINC_RS29300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLINC_RS29305	COG0601	transmembrane transport
SLINC_RS29310	COG0747	negative chemotaxis
SLINC_RS29320	COG4608	Belongs to the ABC transporter superfamily
SLINC_RS29335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLINC_RS29350	COG1131	(ABC) transporter
SLINC_RS29360	COG4585	Histidine kinase
SLINC_RS29365	COG2197	response regulator
SLINC_RS29400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLINC_RS29410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SLINC_RS29420	COG2818	Glycosylase
SLINC_RS29425	COG1024	Enoyl-CoA hydratase
SLINC_RS29440	COG1595	DNA-templated transcription, initiation
SLINC_RS29450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLINC_RS29455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLINC_RS29490	COG0598	Magnesium transport protein CorA
SLINC_RS29500	COG2814	Major facilitator Superfamily
SLINC_RS29515	COG2095	MarC family integral membrane protein
SLINC_RS29520	COG1432	Conserved Protein
SLINC_RS29570	COG0747	negative chemotaxis
SLINC_RS29575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLINC_RS29580	COG0601	transmembrane transport
SLINC_RS29590	COG0297	glycogen (starch) synthase activity
SLINC_RS29640	COG0210	DNA helicase
SLINC_RS29675	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SLINC_RS29730	COG3480	Lon protease (S16) C-terminal proteolytic domain
SLINC_RS29740	COG1615	UPF0182 protein
SLINC_RS29785	COG0483	inositol monophosphate 1-phosphatase activity
SLINC_RS29800	COG1162	GTPase activity
SLINC_RS29805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SLINC_RS29815	COG2135	peptidase activity
SLINC_RS29825	COG1595	DNA-templated transcription, initiation
SLINC_RS29830	COG5662	AntiSigma factor
SLINC_RS29855	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SLINC_RS29855	COG2199	diguanylate cyclase activity
SLINC_RS29870	COG0242	peptide deformylase activity
SLINC_RS29880	COG2124	cytochrome p450
SLINC_RS29930	COG1966	Carbon starvation protein
SLINC_RS29935	COG2188	Transcriptional regulator
SLINC_RS29940	COG2182	Extracellular solute-binding protein
SLINC_RS29945	COG1175	transmembrane transport
SLINC_RS29950	COG0395	ABC-type sugar transport system, permease component
SLINC_RS29955	COG1472	Belongs to the glycosyl hydrolase 3 family
SLINC_RS29960	COG0363	glucosamine-6-phosphate deaminase activity
SLINC_RS29965	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS29985	COG1597	lipid kinase activity
SLINC_RS30015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SLINC_RS30025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLINC_RS30060	COG4941	Belongs to the sigma-70 factor family
SLINC_RS30080	COG4977	sequence-specific DNA binding
SLINC_RS30095	COG2326	polyphosphate kinase activity
SLINC_RS30140	COG1136	(ABC) transporter
SLINC_RS30145	COG0577	efflux transmembrane transporter activity
SLINC_RS30145	COG1136	(ABC) transporter
SLINC_RS30150	COG1126	abc transporter atp-binding protein
SLINC_RS30165	COG0281	malic enzyme
SLINC_RS30170	COG0604	alcohol dehydrogenase
SLINC_RS30230	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SLINC_RS30250	COG0567	Dehydrogenase, E1 component
SLINC_RS30250	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLINC_RS30255	COG2205	protein histidine kinase activity
SLINC_RS30260	COG0745	RESPONSE REGULATOR receiver
SLINC_RS30275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SLINC_RS30345	COG1309	transcriptional regulator
SLINC_RS30375	COG2205	protein histidine kinase activity
SLINC_RS30400	COG1793	dna ligase
SLINC_RS30400	COG3285	dna ligase
SLINC_RS30405	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SLINC_RS30470	COG2816	NAD+ diphosphatase activity
SLINC_RS30580	COG0745	RESPONSE REGULATOR receiver
SLINC_RS30585	COG0018	arginyl-trna synthetase
SLINC_RS30590	COG0019	diaminopimelate decarboxylase activity
SLINC_RS30595	COG0460	homoserine dehydrogenase
SLINC_RS30600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SLINC_RS30605	COG0083	homoserine kinase activity
SLINC_RS30620	COG0254	rRNA binding
SLINC_RS30625	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SLINC_RS30630	COG2890	protein-(glutamine-N5) methyltransferase activity
SLINC_RS30640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLINC_RS30645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLINC_RS30665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLINC_RS30670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SLINC_RS30675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLINC_RS30680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SLINC_RS30685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SLINC_RS30690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SLINC_RS30695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SLINC_RS30710	COG2197	response regulator
SLINC_RS30735	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS30750	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SLINC_RS30785	COG1131	(ABC) transporter
SLINC_RS30805	COG0346	lactoylglutathione lyase activity
SLINC_RS30810	COG0183	Belongs to the thiolase family
SLINC_RS30825	COG0745	RESPONSE REGULATOR receiver
SLINC_RS30910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS30910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS30950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SLINC_RS30955	COG0857	belongs to the CobB CobQ family
SLINC_RS30955	COG0280	phosphate acetyltransferase
SLINC_RS30960	COG0205	6-phosphofructokinase activity
SLINC_RS31000	COG0395	ABC-type sugar transport system, permease component
SLINC_RS31005	COG1175	transmembrane transport
SLINC_RS31010	COG1653	transport
SLINC_RS31015	COG4565	transcriptional regulatory protein
SLINC_RS31020	COG3290	protein histidine kinase activity
SLINC_RS31025	COG1301	dicarboxylic acid transport
SLINC_RS31050	COG1132	(ABC) transporter
SLINC_RS31060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SLINC_RS31070	COG0612	Peptidase, M16
SLINC_RS31090	COG1131	(ABC) transporter
SLINC_RS31115	COG0477	Major facilitator Superfamily
SLINC_RS31140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLINC_RS31150	COG0667	Aldo Keto reductase
SLINC_RS31160	COG1522	sequence-specific DNA binding
SLINC_RS31170	COG0492	ferredoxin-NADP+ reductase activity
SLINC_RS31170	COG3118	belongs to the thioredoxin family
SLINC_RS31185	COG2124	cytochrome p450
SLINC_RS31200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLINC_RS31205	COG3281	Trehalose synthase
SLINC_RS31215	COG0366	Alpha amylase catalytic
SLINC_RS31225	COG0058	SHG alpha-glucan phosphorylase activity
SLINC_RS31245	COG1132	(ABC) transporter
SLINC_RS31250	COG1132	(ABC) transporter
SLINC_RS31255	COG1132	(ABC) transporter
SLINC_RS31260	COG1132	(ABC) transporter
SLINC_RS31275	COG4585	Histidine kinase
SLINC_RS31280	COG2197	response regulator
SLINC_RS31350	COG3757	hydrolase, family 25
SLINC_RS31350	COG3409	Peptidoglycan-binding domain 1 protein
SLINC_RS31355	COG0300	oxidoreductase activity
SLINC_RS31355	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS31355	COG3321	synthase
SLINC_RS31355	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS31355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS31375	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SLINC_RS31375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS31405	COG1760	l-serine dehydratase
SLINC_RS31410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLINC_RS31415	COG0509	glycine decarboxylation via glycine cleavage system
SLINC_RS31420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLINC_RS31455	COG0444	Belongs to the ABC transporter superfamily
SLINC_RS31460	COG4608	Belongs to the ABC transporter superfamily
SLINC_RS31465	COG2860	membrane
SLINC_RS31480	COG2378	regulation of single-species biofilm formation
SLINC_RS31505	COG3023	N-Acetylmuramoyl-L-alanine amidase
SLINC_RS31510	COG0482	sulfurtransferase activity
SLINC_RS31520	COG1611	Belongs to the LOG family
SLINC_RS31525	COG4221	oxidoreductase activity
SLINC_RS31535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLINC_RS31545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLINC_RS31550	COG0154	amidase activity
SLINC_RS31560	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLINC_RS31565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLINC_RS31575	COG2409	Drug exporters of the RND superfamily
SLINC_RS31580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLINC_RS31595	COG1672	PFAM Archaeal ATPase
SLINC_RS31595	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLINC_RS31605	COG2133	pyrroloquinoline quinone binding
SLINC_RS31610	COG0667	Aldo Keto reductase
SLINC_RS31620	COG5001	Diguanylate cyclase
SLINC_RS31630	COG0440	acetolactate synthase activity
SLINC_RS31635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SLINC_RS31640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLINC_RS31645	COG0477	Major facilitator Superfamily
SLINC_RS31655	COG4608	Belongs to the ABC transporter superfamily
SLINC_RS31665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLINC_RS31670	COG0747	negative chemotaxis
SLINC_RS31695	COG0506	proline dehydrogenase activity
SLINC_RS31700	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS31715	COG0473	3-isopropylmalate dehydrogenase activity
SLINC_RS31720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SLINC_RS31725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS31740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLINC_RS31775	COG2319	Wd-40 repeat
SLINC_RS31775	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS31785	COG2353	YceI-like domain
SLINC_RS31790	COG5492	domain, Protein
SLINC_RS31795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLINC_RS31815	COG2018	Roadblock/LC7 domain
SLINC_RS31835	COG2018	Roadblock/LC7 domain
SLINC_RS31840	COG5002	protein histidine kinase activity
SLINC_RS31850	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLINC_RS31855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SLINC_RS31895	COG1414	Transcriptional regulator
SLINC_RS31900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SLINC_RS31905	COG0066	3-isopropylmalate dehydratase activity
SLINC_RS31915	COG0776	regulation of translation
SLINC_RS31925	COG1920	GTP binding
SLINC_RS31935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SLINC_RS31940	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLINC_RS31960	COG0351	phosphomethylpyrimidine kinase
SLINC_RS31970	COG1461	Dihydroxyacetone kinase
SLINC_RS31980	COG0326	Molecular chaperone. Has ATPase activity
SLINC_RS31990	COG0742	ribosomal rna small subunit methyltransferase
SLINC_RS31995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SLINC_RS32010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SLINC_RS32015	COG0571	ribonuclease III activity
SLINC_RS32020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLINC_RS32025	COG1733	regulation of RNA biosynthetic process
SLINC_RS32030	COG2340	Cysteine-rich secretory protein family
SLINC_RS32035	COG1254	Belongs to the acylphosphatase family
SLINC_RS32045	COG1196	nuclear chromosome segregation
SLINC_RS32050	COG0477	Major facilitator Superfamily
SLINC_RS32085	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SLINC_RS32095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLINC_RS32105	COG0442	prolyl-tRNA aminoacylation
SLINC_RS32115	COG0228	four-way junction DNA binding
SLINC_RS32120	COG1837	Belongs to the UPF0109 family
SLINC_RS32125	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SLINC_RS32130	COG0336	Belongs to the RNA methyltransferase TrmD family
SLINC_RS32135	COG0335	large ribosomal subunit rRNA binding
SLINC_RS32145	COG0681	Belongs to the peptidase S26 family
SLINC_RS32150	COG0681	Belongs to the peptidase S26 family
SLINC_RS32170	COG0792	nuclease activity
SLINC_RS32185	COG1191	sigma factor activity
SLINC_RS32200	COG0052	Belongs to the universal ribosomal protein uS2 family
SLINC_RS32205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SLINC_RS32210	COG0528	UMP kinase activity
SLINC_RS32215	COG0233	cytoplasmic translational termination
SLINC_RS32220	COG0575	Belongs to the CDS family
SLINC_RS32250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SLINC_RS32260	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SLINC_RS32265	COG3842	ATPase activity
SLINC_RS32295	COG1136	(ABC) transporter
SLINC_RS32300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLINC_RS32310	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS32350	COG0584	glycerophosphoryl diester phosphodiesterase
SLINC_RS32355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLINC_RS32385	COG3842	ATPase activity
SLINC_RS32390	COG1176	ABC-type spermidine putrescine transport system, permease component I
SLINC_RS32395	COG1177	transmembrane transport
SLINC_RS32400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS32430	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS32440	COG1653	transport
SLINC_RS32445	COG4209	transmembrane transport
SLINC_RS32450	COG0395	ABC-type sugar transport system, permease component
SLINC_RS32500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLINC_RS32500	COG0515	serine threonine protein kinase
SLINC_RS32510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SLINC_RS32515	COG0750	zinc metalloprotease
SLINC_RS32520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLINC_RS32535	COG0442	prolyl-tRNA aminoacylation
SLINC_RS32555	COG0779	Required for maturation of 30S ribosomal subunits
SLINC_RS32570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SLINC_RS32580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SLINC_RS32585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SLINC_RS32600	COG0455	bacterial-type flagellum organization
SLINC_RS32620	COG1404	Belongs to the peptidase S8 family
SLINC_RS32680	COG1674	ftsk spoiiie
SLINC_RS32695	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SLINC_RS32700	COG1185	polyribonucleotide nucleotidyltransferase activity
SLINC_RS32705	COG0612	Peptidase, M16
SLINC_RS32710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SLINC_RS32730	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SLINC_RS32735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLINC_RS32740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SLINC_RS32775	COG2208	phosphoserine phosphatase activity
SLINC_RS32775	COG2770	Histidine kinase
SLINC_RS32780	COG2205	protein histidine kinase activity
SLINC_RS32780	COG3850	Histidine kinase
SLINC_RS32780	COG4999	Histidine kinase
SLINC_RS32780	COG3437	response regulator, receiver
SLINC_RS32795	COG1674	ftsk spoiiie
SLINC_RS32805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLINC_RS32815	COG1058	Belongs to the CinA family
SLINC_RS32815	COG1546	Belongs to the CinA family
SLINC_RS32820	COG1396	sequence-specific DNA binding
SLINC_RS32825	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS32830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLINC_RS32835	COG1201	RNA secondary structure unwinding
SLINC_RS32860	COG0628	permease
SLINC_RS32880	COG0577	efflux transmembrane transporter activity
SLINC_RS32895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLINC_RS32900	COG0765	amino acid transport
SLINC_RS32905	COG0765	amino acid transport
SLINC_RS32910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLINC_RS32915	COG1126	abc transporter atp-binding protein
SLINC_RS32920	COG0745	RESPONSE REGULATOR receiver
SLINC_RS32925	COG2205	protein histidine kinase activity
SLINC_RS32930	COG2358	TRAP transporter, solute receptor (TAXI family
SLINC_RS32945	COG3851	Histidine kinase
SLINC_RS32950	COG2197	response regulator
SLINC_RS32965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS32970	COG0488	(ABC) transporter
SLINC_RS32975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLINC_RS32995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SLINC_RS33005	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SLINC_RS33010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLINC_RS33020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SLINC_RS33055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SLINC_RS33060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SLINC_RS33065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SLINC_RS33080	COG0588	phosphoglycerate mutase activity
SLINC_RS33100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SLINC_RS33115	COG0514	ATP-dependent DNA helicase (RecQ)
SLINC_RS33140	COG1802	Transcriptional regulator
SLINC_RS33145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLINC_RS33160	COG0187	DNA topoisomerase II activity
SLINC_RS33175	COG2197	response regulator
SLINC_RS33185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLINC_RS33190	COG4565	transcriptional regulatory protein
SLINC_RS33195	COG3290	protein histidine kinase activity
SLINC_RS33210	COG0372	Belongs to the citrate synthase family
SLINC_RS33230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLINC_RS33235	COG0612	Peptidase, M16
SLINC_RS33250	COG1802	Transcriptional regulator
SLINC_RS33255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLINC_RS33260	COG0045	succinate-CoA ligase (ADP-forming) activity
SLINC_RS33260	COG1042	CoA-binding domain protein
SLINC_RS33260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLINC_RS33275	COG1435	thymidine kinase activity
SLINC_RS33305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SLINC_RS33315	COG0745	RESPONSE REGULATOR receiver
SLINC_RS33320	COG2205	protein histidine kinase activity
SLINC_RS33345	COG0756	dUTP diphosphatase activity
SLINC_RS33360	COG1136	(ABC) transporter
SLINC_RS33360	COG0577	efflux transmembrane transporter activity
SLINC_RS33390	COG0569	domain protein
SLINC_RS33395	COG0531	amino acid
SLINC_RS33400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SLINC_RS33420	COG1201	RNA secondary structure unwinding
SLINC_RS33465	COG4974	Belongs to the 'phage' integrase family
SLINC_RS33495	COG1869	D-ribose catabolic process
SLINC_RS33500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLINC_RS33510	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS33515	COG1879	ABC-type sugar transport system periplasmic component
SLINC_RS33520	COG1609	Transcriptional regulator
SLINC_RS33540	COG2304	oxidoreductase activity
SLINC_RS33570	COG0640	Transcriptional regulator
SLINC_RS33575	COG0657	acetylesterase activity
SLINC_RS33620	COG0243	molybdopterin cofactor binding
SLINC_RS33625	COG1799	cell septum assembly
SLINC_RS33630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SLINC_RS33660	COG1216	Glycosyl transferase, family 2
SLINC_RS33670	COG1131	(ABC) transporter
SLINC_RS33720	COG0367	asparagine synthase
SLINC_RS33725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLINC_RS33730	COG1132	(ABC) transporter
SLINC_RS33735	COG1132	(ABC) transporter
SLINC_RS33740	COG0156	8-amino-7-oxononanoate synthase activity
SLINC_RS33745	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS33755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SLINC_RS33765	COG2255	four-way junction helicase activity
SLINC_RS33775	COG0475	glutathione-regulated potassium exporter activity
SLINC_RS33800	COG2235	arginine
SLINC_RS33805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SLINC_RS33815	COG1024	Enoyl-CoA hydratase
SLINC_RS33820	COG1902	pentaerythritol trinitrate reductase activity
SLINC_RS33865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLINC_RS33870	COG2226	methyltransferase
SLINC_RS33880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SLINC_RS33890	COG2205	protein histidine kinase activity
SLINC_RS33900	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS33905	COG3739	integral membrane protein
SLINC_RS33915	COG3458	cephalosporin-C deacetylase activity
SLINC_RS33920	COG4209	transmembrane transport
SLINC_RS33925	COG0395	ABC-type sugar transport system, permease component
SLINC_RS33930	COG1653	transport
SLINC_RS33960	COG1653	transport
SLINC_RS33965	COG1175	transmembrane transport
SLINC_RS33970	COG0395	ABC-type sugar transport system, permease component
SLINC_RS33975	COG1940	carbohydrate kinase activity
SLINC_RS33980	COG4213	ABC transporter substrate-binding protein
SLINC_RS33990	COG4214	carbohydrate transport
SLINC_RS33995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLINC_RS34000	COG0531	amino acid
SLINC_RS34010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SLINC_RS34040	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS34040	COG1024	Enoyl-CoA hydratase
SLINC_RS34045	COG0183	Belongs to the thiolase family
SLINC_RS34050	COG1609	Transcriptional regulator
SLINC_RS34055	COG3250	beta-galactosidase activity
SLINC_RS34065	COG1175	transmembrane transport
SLINC_RS34075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SLINC_RS34090	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SLINC_RS34095	COG2197	response regulator
SLINC_RS34110	COG2226	methyltransferase
SLINC_RS34115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLINC_RS34125	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS34130	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS34135	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS34145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLINC_RS34160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLINC_RS34180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLINC_RS34185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLINC_RS34200	COG2197	response regulator
SLINC_RS34205	COG4585	Histidine kinase
SLINC_RS34230	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLINC_RS34245	COG3253	May function as heme-dependent peroxidase
SLINC_RS34265	COG3220	belongs to the UPF0276 family
SLINC_RS34275	COG4152	abc transporter atp-binding protein
SLINC_RS34290	COG0726	polysaccharide deacetylase
SLINC_RS34295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS34295	COG0723	plastoquinol--plastocyanin reductase activity
SLINC_RS34305	COG0330	HflC and HflK could
SLINC_RS34340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SLINC_RS34345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLINC_RS34350	COG2814	Major facilitator Superfamily
SLINC_RS34355	COG0640	Transcriptional regulator
SLINC_RS34370	COG1472	Belongs to the glycosyl hydrolase 3 family
SLINC_RS34390	COG0395	ABC-type sugar transport system, permease component
SLINC_RS34395	COG1175	transmembrane transport
SLINC_RS34415	COG1737	Transcriptional regulator
SLINC_RS34420	COG4821	SIS domain
SLINC_RS34425	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLINC_RS34445	COG0747	negative chemotaxis
SLINC_RS34450	COG0601	transmembrane transport
SLINC_RS34455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLINC_RS34495	COG0745	RESPONSE REGULATOR receiver
SLINC_RS34500	COG5002	protein histidine kinase activity
SLINC_RS34505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SLINC_RS34510	COG2205	protein histidine kinase activity
SLINC_RS34515	COG0745	RESPONSE REGULATOR receiver
SLINC_RS34540	COG2124	cytochrome p450
SLINC_RS34560	COG1174	glycine betaine transport
SLINC_RS34580	COG2018	Roadblock/LC7 domain
SLINC_RS34595	COG2755	lipolytic protein G-D-S-L family
SLINC_RS34600	COG1940	carbohydrate kinase activity
SLINC_RS34665	COG0640	Transcriptional regulator
SLINC_RS34670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLINC_RS34675	COG1316	TRANSCRIPTIONal
SLINC_RS34680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLINC_RS34705	COG1404	Belongs to the peptidase S8 family
SLINC_RS34710	COG0702	epimerase
SLINC_RS34725	COG1309	transcriptional regulator
SLINC_RS34745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS34765	COG0504	CTP synthase activity
SLINC_RS34775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLINC_RS34780	COG1280	lysine exporter protein (LysE YggA)
SLINC_RS34860	COG0583	DNA-binding transcription factor activity
SLINC_RS34885	COG1175	transmembrane transport
SLINC_RS34905	COG0745	RESPONSE REGULATOR receiver
SLINC_RS34910	COG2205	protein histidine kinase activity
SLINC_RS34965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS34970	COG1116	anion transmembrane transporter activity
SLINC_RS34990	COG0529	Catalyzes the synthesis of activated sulfate
SLINC_RS34995	COG0175	sulfate reduction
SLINC_RS35025	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS35030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLINC_RS35035	COG2423	ornithine cyclodeaminase activity
SLINC_RS35150	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS35160	COG1175	transmembrane transport
SLINC_RS35170	COG1609	Transcriptional regulator
SLINC_RS35175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLINC_RS35185	COG1175	transmembrane transport
SLINC_RS35190	COG0395	ABC-type sugar transport system, permease component
SLINC_RS35215	COG1609	Transcriptional regulator
SLINC_RS35220	COG2040	homocysteine
SLINC_RS35225	COG0531	amino acid
SLINC_RS35260	COG2755	lipolytic protein G-D-S-L family
SLINC_RS35280	COG0596	Alpha beta hydrolase
SLINC_RS35310	COG0738	Major facilitator superfamily
SLINC_RS35325	COG1131	(ABC) transporter
SLINC_RS35340	COG1175	transmembrane transport
SLINC_RS35355	COG0277	FAD linked oxidase domain protein
SLINC_RS35375	COG1162	GTPase activity
SLINC_RS35385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLINC_RS35430	COG1802	Transcriptional regulator
SLINC_RS35455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLINC_RS35460	COG2252	PERMEase
SLINC_RS35480	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SLINC_RS35485	COG3940	Belongs to the glycosyl hydrolase 43 family
SLINC_RS35490	COG3940	Belongs to the glycosyl hydrolase 43 family
SLINC_RS35520	COG1742	UPF0060 membrane protein
SLINC_RS35530	COG0385	Bile acid
SLINC_RS35555	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS35560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLINC_RS35595	COG0598	Magnesium transport protein CorA
SLINC_RS35680	COG0583	DNA-binding transcription factor activity
SLINC_RS35700	COG2197	response regulator
SLINC_RS35705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLINC_RS35710	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS35725	COG1472	Belongs to the glycosyl hydrolase 3 family
SLINC_RS35730	COG5297	Belongs to the glycosyl hydrolase family 6
SLINC_RS35745	COG3960	tartronate-semialdehyde synthase activity
SLINC_RS35750	COG2084	Dehydrogenase
SLINC_RS35755	COG3622	Belongs to the hyi family
SLINC_RS35775	COG2351	hydroxyisourate hydrolase activity
SLINC_RS35790	COG2233	PERMEase
SLINC_RS35810	COG1733	regulation of RNA biosynthetic process
SLINC_RS35825	COG0436	Aminotransferase
SLINC_RS35830	COG1733	regulation of RNA biosynthetic process
SLINC_RS35845	COG4264	IucA IucC family
SLINC_RS35870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLINC_RS35925	COG1132	(ABC) transporter
SLINC_RS35930	COG1132	(ABC) transporter
SLINC_RS35955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SLINC_RS35960	COG0746	molybdenum cofactor guanylyltransferase activity
SLINC_RS35975	COG1414	Transcriptional regulator
SLINC_RS35980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLINC_RS35985	COG4266	Belongs to the allantoicase family
SLINC_RS35990	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS36015	COG2197	response regulator
SLINC_RS36025	COG0673	inositol 2-dehydrogenase activity
SLINC_RS36030	COG2188	Transcriptional regulator
SLINC_RS36035	COG1940	carbohydrate kinase activity
SLINC_RS36045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLINC_RS36055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS36060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SLINC_RS36080	COG2936	dipeptidyl-peptidase activity
SLINC_RS36090	COG0405	Gamma-glutamyltransferase
SLINC_RS36100	COG0702	epimerase
SLINC_RS36115	COG0583	DNA-binding transcription factor activity
SLINC_RS36120	COG0542	response to heat
SLINC_RS36145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLINC_RS36160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLINC_RS36170	COG1953	Uracil, thiamine, allantoin
SLINC_RS36185	COG3851	Histidine kinase
SLINC_RS36190	COG2197	response regulator
SLINC_RS36195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLINC_RS36205	COG0483	inositol monophosphate 1-phosphatase activity
SLINC_RS36215	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SLINC_RS36240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLINC_RS36255	COG0529	Catalyzes the synthesis of activated sulfate
SLINC_RS36260	COG2814	Major facilitator Superfamily
SLINC_RS36265	COG4977	sequence-specific DNA binding
SLINC_RS36275	COG2197	response regulator
SLINC_RS36290	COG4171	peptide transport system, permease
SLINC_RS36295	COG0601	transmembrane transport
SLINC_RS36300	COG0747	negative chemotaxis
SLINC_RS36315	COG0640	Transcriptional regulator
SLINC_RS36335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SLINC_RS36350	COG1929	Belongs to the glycerate kinase type-1 family
SLINC_RS36375	COG0559	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS36395	COG0688	phosphatidylethanolamine metabolic process
SLINC_RS36400	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS36415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS36415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLINC_RS36420	COG0604	alcohol dehydrogenase
SLINC_RS36430	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS36450	COG0596	Alpha beta hydrolase
SLINC_RS36470	COG2208	phosphoserine phosphatase activity
SLINC_RS36470	COG1366	Belongs to the anti-sigma-factor antagonist family
SLINC_RS36470	COG2172	sigma factor antagonist activity
SLINC_RS36475	COG2226	methyltransferase
SLINC_RS36535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLINC_RS36540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLINC_RS36570	COG2814	Major facilitator Superfamily
SLINC_RS36580	COG2362	D-Aminopeptidase
SLINC_RS36585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLINC_RS36590	COG4946	Tricorn protease homolog
SLINC_RS36590	COG0823	Involved in the tonB-independent uptake of proteins
SLINC_RS36590	COG1506	peptidase
SLINC_RS36595	COG1619	proteins homologs of microcin C7 resistance protein MccF
SLINC_RS36625	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS36630	COG4948	Mandelate Racemase Muconate Lactonizing
SLINC_RS36635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS36650	COG1793	dna ligase
SLINC_RS36650	COG3285	dna ligase
SLINC_RS36715	COG1597	lipid kinase activity
SLINC_RS36720	COG0488	(ABC) transporter
SLINC_RS36740	COG0693	protein deglycase activity
SLINC_RS36750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SLINC_RS36750	COG0517	IMP dehydrogenase activity
SLINC_RS36770	COG0028	Belongs to the TPP enzyme family
SLINC_RS36800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SLINC_RS36840	COG0443	Heat shock 70 kDa protein
SLINC_RS36870	COG2154	pterin-4-alpha-carbinolamine dehydratase
SLINC_RS36875	COG2226	methyltransferase
SLINC_RS36890	COG2378	regulation of single-species biofilm formation
SLINC_RS36895	COG3401	FG-GAP repeat protein
SLINC_RS36905	COG5297	Belongs to the glycosyl hydrolase family 6
SLINC_RS36905	COG4733	cellulase activity
SLINC_RS36910	COG5297	Belongs to the glycosyl hydrolase family 6
SLINC_RS36965	COG1335	isochorismatase
SLINC_RS36975	COG0583	DNA-binding transcription factor activity
SLINC_RS36980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SLINC_RS36990	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLINC_RS36995	COG3383	formate dehydrogenase (NAD+) activity
SLINC_RS37000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SLINC_RS37015	COG2409	Drug exporters of the RND superfamily
SLINC_RS37025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLINC_RS37040	COG1940	carbohydrate kinase activity
SLINC_RS37045	COG1129	ABC transporter
SLINC_RS37050	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS37060	COG0673	inositol 2-dehydrogenase activity
SLINC_RS37070	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS37085	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SLINC_RS37125	COG2223	nitrite transmembrane transporter activity
SLINC_RS37135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLINC_RS37145	COG0045	succinate-CoA ligase (ADP-forming) activity
SLINC_RS37155	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS37170	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLINC_RS37175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS37180	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS37185	COG1120	ATPase activity
SLINC_RS37195	COG1132	(ABC) transporter
SLINC_RS37205	COG1132	(ABC) transporter
SLINC_RS37230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS37235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLINC_RS37265	COG0747	negative chemotaxis
SLINC_RS37300	COG0297	glycogen (starch) synthase activity
SLINC_RS37315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLINC_RS37320	COG2423	ornithine cyclodeaminase activity
SLINC_RS37325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS37350	COG3467	pyridoxamine 5'-phosphate
SLINC_RS37355	COG0346	lactoylglutathione lyase activity
SLINC_RS37365	COG0477	Major facilitator Superfamily
SLINC_RS37375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SLINC_RS37380	COG1082	Xylose isomerase domain protein TIM barrel
SLINC_RS37380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SLINC_RS37390	COG0588	phosphoglycerate mutase activity
SLINC_RS37395	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SLINC_RS37400	COG0166	Belongs to the GPI family
SLINC_RS37415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLINC_RS37440	COG2409	Drug exporters of the RND superfamily
SLINC_RS37450	COG2197	response regulator
SLINC_RS37455	COG3850	Histidine kinase
SLINC_RS37470	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS37495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLINC_RS37500	COG3250	beta-galactosidase activity
SLINC_RS37510	COG1175	transmembrane transport
SLINC_RS37520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLINC_RS37530	COG1486	melibiose metabolic process
SLINC_RS37555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLINC_RS37585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS37595	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLINC_RS37600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLINC_RS37605	COG3938	Belongs to the proline racemase family
SLINC_RS37615	COG1116	anion transmembrane transporter activity
SLINC_RS37620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS37625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS37635	COG1414	Transcriptional regulator
SLINC_RS37655	COG2197	response regulator
SLINC_RS37705	COG1175	transmembrane transport
SLINC_RS37710	COG0395	ABC-type sugar transport system, permease component
SLINC_RS37715	COG1940	carbohydrate kinase activity
SLINC_RS37735	COG0477	Major facilitator Superfamily
SLINC_RS37740	COG3511	phospholipase C
SLINC_RS37770	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SLINC_RS37775	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLINC_RS37775	COG1672	PFAM Archaeal ATPase
SLINC_RS37785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS37790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLINC_RS37795	COG3485	protocatechuate 3,4-dioxygenase
SLINC_RS37800	COG3485	protocatechuate 3,4-dioxygenase
SLINC_RS37805	COG0183	Belongs to the thiolase family
SLINC_RS37835	COG1793	dna ligase
SLINC_RS37885	COG1834	amidinotransferase
SLINC_RS37890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLINC_RS37895	COG0488	(ABC) transporter
SLINC_RS37920	COG1515	deoxyribonuclease V activity
SLINC_RS37925	COG3268	Saccharopine dehydrogenase
SLINC_RS37935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLINC_RS37940	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS37945	COG0183	Belongs to the thiolase family
SLINC_RS37950	COG1024	Enoyl-CoA hydratase
SLINC_RS37950	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS37960	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS37970	COG1113	amino acid transport
SLINC_RS37975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLINC_RS37985	COG2936	dipeptidyl-peptidase activity
SLINC_RS37995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SLINC_RS38010	COG0488	(ABC) transporter
SLINC_RS38020	COG2183	response to ionizing radiation
SLINC_RS38030	COG4977	sequence-specific DNA binding
SLINC_RS38040	COG1024	Enoyl-CoA hydratase
SLINC_RS38055	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLINC_RS38100	COG1134	teichoic acid transport
SLINC_RS38105	COG1562	ergosterol biosynthetic process
SLINC_RS38115	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLINC_RS38125	COG1657	PFAM Prenyltransferase squalene oxidase
SLINC_RS38140	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLINC_RS38145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLINC_RS38195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SLINC_RS38240	COG1063	alcohol dehydrogenase
SLINC_RS38245	COG0156	8-amino-7-oxononanoate synthase activity
SLINC_RS38250	COG0583	DNA-binding transcription factor activity
SLINC_RS38300	COG0174	glutamine synthetase
SLINC_RS38315	COG2197	response regulator
SLINC_RS38325	COG1136	(ABC) transporter
SLINC_RS38340	COG0006	proline dipeptidase activity
SLINC_RS38345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SLINC_RS38350	COG0022	dehydrogenase e1 component
SLINC_RS38355	COG0402	S-adenosylhomocysteine deaminase activity
SLINC_RS38360	COG1917	Cupin 2, conserved barrel domain protein
SLINC_RS38365	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS38390	COG0183	Belongs to the thiolase family
SLINC_RS38445	COG1132	(ABC) transporter
SLINC_RS38465	COG0494	nUDIX hydrolase
SLINC_RS38475	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SLINC_RS38480	COG2188	Transcriptional regulator
SLINC_RS38485	COG3962	Belongs to the TPP enzyme family
SLINC_RS38515	COG0673	inositol 2-dehydrogenase activity
SLINC_RS38520	COG0673	inositol 2-dehydrogenase activity
SLINC_RS38530	COG0673	inositol 2-dehydrogenase activity
SLINC_RS38535	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS38545	COG1609	Transcriptional regulator
SLINC_RS38555	COG1609	Transcriptional regulator
SLINC_RS38565	COG0477	Major facilitator Superfamily
SLINC_RS38570	COG1063	alcohol dehydrogenase
SLINC_RS38580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLINC_RS38585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SLINC_RS38605	COG0477	Major facilitator Superfamily
SLINC_RS38635	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS38645	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLINC_RS38665	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLINC_RS38670	COG1007	ATP synthesis coupled electron transport
SLINC_RS38685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS38690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS38700	COG2197	response regulator
SLINC_RS38725	COG2124	cytochrome p450
SLINC_RS38740	COG2838	Isocitrate dehydrogenase
SLINC_RS38745	COG0668	transmembrane transport
SLINC_RS38760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLINC_RS38775	COG1024	Enoyl-CoA hydratase
SLINC_RS38785	COG1132	(ABC) transporter
SLINC_RS38805	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SLINC_RS38835	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SLINC_RS38855	COG0297	glycogen (starch) synthase activity
SLINC_RS38860	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SLINC_RS38880	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS38925	COG2186	Transcriptional regulator
SLINC_RS38930	COG1879	ABC-type sugar transport system periplasmic component
SLINC_RS38935	COG1129	ABC transporter
SLINC_RS38940	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS38945	COG4948	Mandelate Racemase Muconate Lactonizing
SLINC_RS38950	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS38965	COG3618	amidohydrolase
SLINC_RS38985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLINC_RS39020	COG2945	thiolester hydrolase activity
SLINC_RS39020	COG0596	Alpha beta hydrolase
SLINC_RS39025	COG0531	amino acid
SLINC_RS39040	COG0726	polysaccharide deacetylase
SLINC_RS39085	COG0583	DNA-binding transcription factor activity
SLINC_RS39095	COG1053	succinate dehydrogenase
SLINC_RS39100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SLINC_RS39130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS39140	COG0523	cobalamin synthesis protein
SLINC_RS39165	COG1733	regulation of RNA biosynthetic process
SLINC_RS39175	COG3360	Dodecin
SLINC_RS39180	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SLINC_RS39185	COG0121	glutamine amidotransferase
SLINC_RS39190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLINC_RS39210	COG2268	Band 7 protein
SLINC_RS39230	COG0596	Alpha beta hydrolase
SLINC_RS39235	COG1414	Transcriptional regulator
SLINC_RS39240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLINC_RS39295	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS39340	COG2197	response regulator
SLINC_RS39345	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS39350	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS39390	COG3409	Peptidoglycan-binding domain 1 protein
SLINC_RS39415	COG1408	metallophosphoesterase
SLINC_RS39430	COG4585	Histidine kinase
SLINC_RS39435	COG2197	response regulator
SLINC_RS39440	COG1802	Transcriptional regulator
SLINC_RS39470	COG2132	Multicopper oxidase
SLINC_RS39475	COG2132	Multicopper oxidase
SLINC_RS39480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SLINC_RS39510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLINC_RS39520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLINC_RS39525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SLINC_RS39540	COG3250	beta-galactosidase activity
SLINC_RS39555	COG0477	Major facilitator Superfamily
SLINC_RS39565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLINC_RS39570	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS39580	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SLINC_RS39590	COG0583	DNA-binding transcription factor activity
SLINC_RS39595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SLINC_RS39610	COG0148	phosphopyruvate hydratase activity
SLINC_RS39620	COG1609	Transcriptional regulator
SLINC_RS39625	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLINC_RS39630	COG2271	Major facilitator Superfamily
SLINC_RS39635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLINC_RS39670	COG0726	polysaccharide deacetylase
SLINC_RS39675	COG2319	Wd-40 repeat
SLINC_RS39675	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS39680	COG1404	Belongs to the peptidase S8 family
SLINC_RS39690	COG2197	response regulator
SLINC_RS39710	COG0477	Major facilitator Superfamily
SLINC_RS39715	COG0300	oxidoreductase activity
SLINC_RS39760	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS39765	COG1278	Cold shock
SLINC_RS39770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLINC_RS39780	COG1902	pentaerythritol trinitrate reductase activity
SLINC_RS39790	COG2255	four-way junction helicase activity
SLINC_RS39820	COG1959	2 iron, 2 sulfur cluster binding
SLINC_RS39825	COG1511	domain protein
SLINC_RS39860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLINC_RS39900	COG2409	Drug exporters of the RND superfamily
SLINC_RS39915	COG4585	Histidine kinase
SLINC_RS39920	COG2197	response regulator
SLINC_RS39930	COG3594	Acyltransferase
SLINC_RS39945	COG1609	Transcriptional regulator
SLINC_RS39955	COG1175	transmembrane transport
SLINC_RS39960	COG0395	ABC-type sugar transport system, permease component
SLINC_RS39975	COG4221	oxidoreductase activity
SLINC_RS39985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLINC_RS40025	COG0583	DNA-binding transcription factor activity
SLINC_RS40045	COG1609	Transcriptional regulator
SLINC_RS40055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLINC_RS40075	COG0242	peptide deformylase activity
SLINC_RS40100	COG1131	(ABC) transporter
SLINC_RS40120	COG2409	Drug exporters of the RND superfamily
SLINC_RS40125	COG4585	Histidine kinase
SLINC_RS40130	COG2197	response regulator
SLINC_RS40145	COG0436	Aminotransferase
SLINC_RS40150	COG1819	glycosyl
SLINC_RS40160	COG1609	Transcriptional regulator
SLINC_RS40170	COG1175	transmembrane transport
SLINC_RS40180	COG3250	beta-galactosidase activity
SLINC_RS40230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SLINC_RS40240	COG0601	transmembrane transport
SLINC_RS40245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLINC_RS40250	COG0444	Belongs to the ABC transporter superfamily
SLINC_RS40255	COG1124	(ABC) transporter
SLINC_RS40260	COG3396	Phenylacetate-CoA oxygenase
SLINC_RS40265	COG3460	Phenylacetate-CoA oxygenase
SLINC_RS40270	COG3396	Phenylacetate-CoA oxygenase
SLINC_RS40275	COG2151	metal-sulfur cluster biosynthetic enzyme
SLINC_RS40280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLINC_RS40285	COG1609	Transcriptional regulator
SLINC_RS40335	COG3321	synthase
SLINC_RS40335	COG0604	alcohol dehydrogenase
SLINC_RS40335	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS40360	COG1136	(ABC) transporter
SLINC_RS40370	COG1556	Lactate utilization protein
SLINC_RS40375	COG1139	Iron-sulfur cluster binding protein
SLINC_RS40380	COG0247	lactate metabolic process
SLINC_RS40385	COG1070	Carbohydrate kinase
SLINC_RS40390	COG3347	Dehydrogenase
SLINC_RS40390	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS40400	COG2814	Major facilitator Superfamily
SLINC_RS40405	COG3250	beta-galactosidase activity
SLINC_RS40420	COG1129	ABC transporter
SLINC_RS40425	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS40430	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS40435	COG1879	ABC-type sugar transport system periplasmic component
SLINC_RS40450	COG1609	Transcriptional regulator
SLINC_RS40480	COG1357	PFAM Pentapeptide repeats (8 copies)
SLINC_RS40490	COG1309	transcriptional regulator
SLINC_RS40500	COG2706	6-phosphogluconolactonase activity
SLINC_RS40520	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS40520	COG2319	Wd-40 repeat
SLINC_RS40525	COG0583	DNA-binding transcription factor activity
SLINC_RS40605	COG1796	DNA polymerase
SLINC_RS40605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SLINC_RS40610	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS40630	COG2124	cytochrome p450
SLINC_RS40640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLINC_RS40660	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS40700	COG0531	amino acid
SLINC_RS40720	COG0435	Glutathione S-transferase
SLINC_RS40735	COG2124	cytochrome p450
SLINC_RS40750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SLINC_RS40770	COG0667	Aldo Keto reductase
SLINC_RS40805	COG3250	beta-galactosidase activity
SLINC_RS40815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLINC_RS40870	COG2890	protein-(glutamine-N5) methyltransferase activity
SLINC_RS40885	COG0248	Ppx GppA phosphatase
SLINC_RS40895	COG2274	protein secretion by the type I secretion system
SLINC_RS40925	COG1132	(ABC) transporter
SLINC_RS40930	COG1132	(ABC) transporter
SLINC_RS40940	COG0515	serine threonine protein kinase
SLINC_RS40950	COG0517	IMP dehydrogenase activity
SLINC_RS40995	COG0515	serine threonine protein kinase
SLINC_RS41000	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS41045	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SLINC_RS41085	COG0789	Transcriptional regulator
SLINC_RS41105	COG1819	glycosyl
SLINC_RS41130	COG2814	Major facilitator Superfamily
SLINC_RS41145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SLINC_RS41150	COG1120	ATPase activity
SLINC_RS41155	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS41160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLINC_RS41170	COG1132	(ABC) transporter
SLINC_RS41190	COG4221	oxidoreductase activity
SLINC_RS41195	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS41215	COG2182	Extracellular solute-binding protein
SLINC_RS41220	COG0395	ABC-type sugar transport system, permease component
SLINC_RS41225	COG1175	transmembrane transport
SLINC_RS41230	COG1940	carbohydrate kinase activity
SLINC_RS41230	COG1846	Transcriptional regulator
SLINC_RS41250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SLINC_RS41265	COG0673	inositol 2-dehydrogenase activity
SLINC_RS41275	COG1309	transcriptional regulator
SLINC_RS41330	COG1940	carbohydrate kinase activity
SLINC_RS41340	COG1175	transmembrane transport
SLINC_RS41345	COG0395	ABC-type sugar transport system, permease component
SLINC_RS41365	COG1072	(Pantothenic acid kinase))
SLINC_RS41395	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLINC_RS41400	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SLINC_RS41445	COG0673	inositol 2-dehydrogenase activity
SLINC_RS41450	COG0667	Aldo Keto reductase
SLINC_RS41480	COG1741	Belongs to the pirin family
SLINC_RS41485	COG1132	(ABC) transporter
SLINC_RS41530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLINC_RS41535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SLINC_RS41540	COG2080	2 iron, 2 sulfur cluster binding
SLINC_RS41585	COG3321	synthase
SLINC_RS41585	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS41585	COG0604	alcohol dehydrogenase
SLINC_RS41590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLINC_RS41605	COG3290	protein histidine kinase activity
SLINC_RS41640	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS41640	COG2319	Wd-40 repeat
SLINC_RS41640	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS41640	COG2319	Wd-40 repeat
SLINC_RS41690	COG1473	amidohydrolase
SLINC_RS41725	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SLINC_RS41740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SLINC_RS41755	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS41755	COG1454	alcohol dehydrogenase
SLINC_RS41795	COG1042	CoA-binding domain protein
SLINC_RS41795	COG0045	succinate-CoA ligase (ADP-forming) activity
SLINC_RS41795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLINC_RS41825	COG0574	Belongs to the PEP-utilizing enzyme family
SLINC_RS41825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLINC_RS41845	COG1366	Belongs to the anti-sigma-factor antagonist family
SLINC_RS41850	COG1063	alcohol dehydrogenase
SLINC_RS41885	COG0667	Aldo Keto reductase
SLINC_RS41900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLINC_RS41975	COG2192	nodulation
SLINC_RS42025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SLINC_RS42050	COG4716	Myosin-crossreactive antigen
SLINC_RS42070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLINC_RS42090	COG1733	regulation of RNA biosynthetic process
SLINC_RS42120	COG1846	Transcriptional regulator
SLINC_RS42130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS42135	COG2326	polyphosphate kinase activity
SLINC_RS42150	COG2239	Acts as a magnesium transporter
SLINC_RS42180	COG2267	carboxylic ester hydrolase activity
SLINC_RS42190	COG0604	alcohol dehydrogenase
SLINC_RS42195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLINC_RS42225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLINC_RS42235	COG1609	Transcriptional regulator
SLINC_RS42245	COG1082	Xylose isomerase domain protein TIM barrel
SLINC_RS42255	COG1082	Xylose isomerase domain protein TIM barrel
SLINC_RS42260	COG2409	Drug exporters of the RND superfamily
SLINC_RS42285	COG0753	catalase activity
SLINC_RS42320	COG0277	FAD linked oxidase domain protein
SLINC_RS42325	COG1597	lipid kinase activity
SLINC_RS42355	COG3321	synthase
SLINC_RS42355	COG3321	synthase
SLINC_RS42355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS42355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS42360	COG0318	PFAM AMP-dependent synthetase and ligase
SLINC_RS42365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLINC_RS42405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLINC_RS42410	COG0395	ABC-type sugar transport system, permease component
SLINC_RS42415	COG1175	transmembrane transport
SLINC_RS42425	COG1349	DNA-binding transcription factor activity
SLINC_RS42440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS42450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SLINC_RS42465	COG1280	lysine exporter protein (LysE YggA)
SLINC_RS42475	COG2076	Multidrug Resistance protein
SLINC_RS42490	COG4585	Histidine kinase
SLINC_RS42495	COG2197	response regulator
SLINC_RS42545	COG3594	Acyltransferase
SLINC_RS42560	COG1609	Transcriptional regulator
SLINC_RS42570	COG1175	transmembrane transport
SLINC_RS42575	COG0395	ABC-type sugar transport system, permease component
SLINC_RS42585	COG3540	Alkaline phosphatase
SLINC_RS42610	COG0640	Transcriptional regulator
SLINC_RS42625	COG0583	DNA-binding transcription factor activity
SLINC_RS42635	COG1765	OsmC-like protein
SLINC_RS42645	COG4977	sequence-specific DNA binding
SLINC_RS42675	COG0154	amidase activity
SLINC_RS42685	COG3833	ABC-type maltose transport systems, permease component
SLINC_RS42705	COG1122	ATPase activity
SLINC_RS42715	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
SLINC_RS42720	COG0310	cobalt ion transport
SLINC_RS42750	COG0726	polysaccharide deacetylase
SLINC_RS42770	COG2318	DinB family
SLINC_RS42790	COG0657	acetylesterase activity
SLINC_RS42795	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS42805	COG1082	Xylose isomerase domain protein TIM barrel
SLINC_RS42845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLINC_RS42850	COG4638	Rieske (2fe-2S)
SLINC_RS42860	COG1609	Transcriptional regulator
SLINC_RS42895	COG1621	beta-fructofuranosidase activity
SLINC_RS42900	COG1609	Transcriptional regulator
SLINC_RS42910	COG1175	transmembrane transport
SLINC_RS42915	COG0395	ABC-type sugar transport system, permease component
SLINC_RS42925	COG1621	beta-fructofuranosidase activity
SLINC_RS42945	COG0745	RESPONSE REGULATOR receiver
SLINC_RS42975	COG4585	Histidine kinase
SLINC_RS43010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SLINC_RS43015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLINC_RS43035	COG0367	asparagine synthase
SLINC_RS43060	COG0438	transferase activity, transferring glycosyl groups
SLINC_RS43070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLINC_RS43085	COG4310	Domain of unknown function (DUF2172)
SLINC_RS43095	COG1215	transferase activity, transferring glycosyl groups
SLINC_RS43110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SLINC_RS43130	COG0583	DNA-binding transcription factor activity
SLINC_RS43135	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SLINC_RS43140	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS43145	COG4175	Glycine betaine
SLINC_RS43145	COG0517	IMP dehydrogenase activity
SLINC_RS43150	COG4176	ABC-type proline glycine betaine transport system permease component
SLINC_RS43180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SLINC_RS43200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLINC_RS43210	COG0028	Belongs to the TPP enzyme family
SLINC_RS43215	COG0281	malic enzyme
SLINC_RS43235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SLINC_RS43245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS43255	COG0667	Aldo Keto reductase
SLINC_RS43275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLINC_RS43295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS43305	COG3321	synthase
SLINC_RS43305	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS43305	COG0604	alcohol dehydrogenase
SLINC_RS43315	COG1335	isochorismatase
SLINC_RS43345	COG0174	glutamine synthetase
SLINC_RS43360	COG4689	acetoacetate decarboxylase
SLINC_RS43375	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLINC_RS43390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SLINC_RS43390	COG0519	Catalyzes the synthesis of GMP from XMP
SLINC_RS43395	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS43400	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SLINC_RS43405	COG1846	Transcriptional regulator
SLINC_RS43410	COG2197	response regulator
SLINC_RS43420	COG1129	ABC transporter
SLINC_RS43465	COG1609	Transcriptional regulator
SLINC_RS43480	COG0395	ABC-type sugar transport system, permease component
SLINC_RS43500	COG1595	DNA-templated transcription, initiation
SLINC_RS43515	COG1131	(ABC) transporter
SLINC_RS43530	COG2197	response regulator
SLINC_RS43540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS43555	COG3842	ATPase activity
SLINC_RS43565	COG1177	transmembrane transport
SLINC_RS43570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLINC_RS43580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLINC_RS43590	COG1309	transcriptional regulator
SLINC_RS43600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLINC_RS43620	COG0142	geranyltranstransferase activity
SLINC_RS43635	COG2084	Dehydrogenase
SLINC_RS43640	COG1733	regulation of RNA biosynthetic process
SLINC_RS43645	COG0148	phosphopyruvate hydratase activity
SLINC_RS43660	COG0077	Prephenate dehydratase
SLINC_RS43660	COG1605	Chorismate mutase
SLINC_RS43700	COG4209	transmembrane transport
SLINC_RS43715	COG3345	alpha-galactosidase
SLINC_RS43720	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS43730	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS43755	COG2755	lipolytic protein G-D-S-L family
SLINC_RS43800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLINC_RS43830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SLINC_RS43850	COG3629	intracellular signal transduction
SLINC_RS43855	COG0738	Major facilitator superfamily
SLINC_RS43890	COG0583	DNA-binding transcription factor activity
SLINC_RS43905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS43915	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS43930	COG1509	lysine 2,3-aminomutase activity
SLINC_RS43950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SLINC_RS43965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLINC_RS43995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SLINC_RS44025	COG3693	PFAM glycoside hydrolase, family 10
SLINC_RS44030	COG3507	Belongs to the glycosyl hydrolase 43 family
SLINC_RS44060	COG1129	ABC transporter
SLINC_RS44065	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS44070	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLINC_RS44115	COG0395	ABC-type sugar transport system, permease component
SLINC_RS44120	COG4948	Mandelate Racemase Muconate Lactonizing
SLINC_RS44125	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS44160	COG0477	Major facilitator Superfamily
SLINC_RS44195	COG3396	Phenylacetate-CoA oxygenase
SLINC_RS44205	COG3396	Phenylacetate-CoA oxygenase
SLINC_RS44210	COG2151	metal-sulfur cluster biosynthetic enzyme
SLINC_RS44220	COG3483	tryptophan 2,3-dioxygenase activity
SLINC_RS44230	COG1595	DNA-templated transcription, initiation
SLINC_RS44260	COG2197	response regulator
SLINC_RS44270	COG1028	Short-chain dehydrogenase reductase Sdr
SLINC_RS44280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLINC_RS44290	COG0367	asparagine synthase
SLINC_RS44370	COG1733	regulation of RNA biosynthetic process
SLINC_RS44380	COG0640	Transcriptional regulator
SLINC_RS44390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SLINC_RS44395	COG1404	Belongs to the peptidase S8 family
SLINC_RS44405	COG1309	transcriptional regulator
SLINC_RS44435	COG2267	carboxylic ester hydrolase activity
SLINC_RS44485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SLINC_RS44505	COG4221	oxidoreductase activity
SLINC_RS44540	COG0300	oxidoreductase activity
SLINC_RS44550	COG1595	DNA-templated transcription, initiation
SLINC_RS44555	COG0346	lactoylglutathione lyase activity
SLINC_RS44580	COG0789	Transcriptional regulator
SLINC_RS44615	COG3293	Transposase
SLINC_RS44625	COG4249	Peptidase C14 caspase catalytic subunit p20
SLINC_RS44625	COG2319	Wd-40 repeat
SLINC_RS44645	COG3293	Transposase
SLINC_RS44650	COG3547	Transposase (IS116 IS110 IS902 family)
SLINC_RS44660	COG2318	DinB family
SLINC_RS44770	COG1051	belongs to the nudix hydrolase family
SLINC_RS44790	COG0583	DNA-binding transcription factor activity
SLINC_RS44795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLINC_RS44810	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLINC_RS44815	COG1960	acyl-CoA dehydrogenase activity
SLINC_RS44820	COG0583	DNA-binding transcription factor activity
SLINC_RS44825	COG0596	Alpha beta hydrolase
SLINC_RS44870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SLINC_RS44875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SLINC_RS44935	COG1012	belongs to the aldehyde dehydrogenase family
SLINC_RS44940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SLINC_RS44970	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SLINC_RS44980	COG1136	(ABC) transporter
SLINC_RS44980	COG0577	efflux transmembrane transporter activity
SLINC_RS44995	COG2197	response regulator
SLINC_RS45015	COG0583	DNA-binding transcription factor activity
SLINC_RS45095	COG4221	oxidoreductase activity
SLINC_RS45225	COG2267	carboxylic ester hydrolase activity
SLINC_RS45270	COG2197	response regulator
SLINC_RS45315	COG1309	transcriptional regulator
SLINC_RS45330	COG4257	antibiotic catabolic process
SLINC_RS45350	COG1609	Transcriptional regulator
SLINC_RS45355	COG1309	transcriptional regulator
SLINC_RS45380	COG1309	transcriptional regulator
SLINC_RS45415	COG1902	pentaerythritol trinitrate reductase activity
SLINC_RS45430	COG1024	Enoyl-CoA hydratase
SLINC_RS45430	COG1250	3-hydroxyacyl-CoA dehydrogenase