locus-tag	class	description
SLIV_RS00080	COG2801	Transposase and inactivated derivatives
SLIV_RS00095	COG1349	DNA-binding transcription factor activity
SLIV_RS00135	COG3293	Transposase
SLIV_RS00150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLIV_RS00175	COG2197	response regulator
SLIV_RS00180	COG4585	Histidine kinase
SLIV_RS00185	COG1136	(ABC) transporter
SLIV_RS00185	COG0577	efflux transmembrane transporter activity
SLIV_RS00275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SLIV_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS00330	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLIV_RS00345	COG1309	transcriptional regulator
SLIV_RS00350	COG3547	Transposase (IS116 IS110 IS902 family)
SLIV_RS00355	COG2226	methyltransferase
SLIV_RS00475	COG0640	Transcriptional regulator
SLIV_RS00480	COG2814	Major facilitator Superfamily
SLIV_RS00505	COG0702	epimerase
SLIV_RS00605	COG2770	Histidine kinase
SLIV_RS00605	COG2208	phosphoserine phosphatase activity
SLIV_RS00615	COG3293	Transposase
SLIV_RS00630	COG0431	NADPH-dependent FMN reductase
SLIV_RS00640	COG3547	Transposase (IS116 IS110 IS902 family)
SLIV_RS00710	COG1335	isochorismatase
SLIV_RS00735	COG2318	DinB family
SLIV_RS00785	COG2197	response regulator
SLIV_RS00790	COG4585	Histidine kinase
SLIV_RS00800	COG1846	Transcriptional regulator
SLIV_RS00805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SLIV_RS00830	COG2807	transmembrane transport
SLIV_RS00840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLIV_RS00845	COG3170	Tfp pilus assembly protein FimV
SLIV_RS00850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLIV_RS00855	COG0789	Transcriptional regulator
SLIV_RS00860	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
SLIV_RS00895	COG1132	(ABC) transporter
SLIV_RS00900	COG1132	(ABC) transporter
SLIV_RS00900	COG2375	cellular response to nickel ion
SLIV_RS00910	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SLIV_RS00930	COG2226	methyltransferase
SLIV_RS00930	COG3433	isochorismatase activity
SLIV_RS00930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLIV_RS00935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLIV_RS00935	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SLIV_RS00940	COG1021	2,3-dihydroxybenzoate-AMP ligase
SLIV_RS00945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLIV_RS00955	COG0601	transmembrane transport
SLIV_RS00995	COG1755	Isoprenylcysteine carboxyl methyltransferase
SLIV_RS01010	COG0302	gtp cyclohydrolase
SLIV_RS01015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLIV_RS01020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SLIV_RS01035	COG0604	alcohol dehydrogenase
SLIV_RS01060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SLIV_RS01065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SLIV_RS01085	COG4989	oxidoreductase activity
SLIV_RS01090	COG0667	Aldo Keto reductase
SLIV_RS01100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLIV_RS01115	COG4585	Histidine kinase
SLIV_RS01120	COG2197	response regulator
SLIV_RS01160	COG0583	DNA-binding transcription factor activity
SLIV_RS01170	COG0148	phosphopyruvate hydratase activity
SLIV_RS01200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLIV_RS01210	COG0406	alpha-ribazole phosphatase activity
SLIV_RS01215	COG4948	Mandelate Racemase Muconate Lactonizing
SLIV_RS01230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLIV_RS01245	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SLIV_RS01250	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SLIV_RS01300	COG2353	YceI-like domain
SLIV_RS01305	COG2045	Belongs to the ComB family
SLIV_RS01325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLIV_RS01350	COG1309	transcriptional regulator
SLIV_RS01360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SLIV_RS01365	COG1737	Transcriptional regulator
SLIV_RS01370	COG2971	BadF BadG BcrA BcrD
SLIV_RS01375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLIV_RS01380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SLIV_RS01385	COG0667	Aldo Keto reductase
SLIV_RS01425	COG1902	pentaerythritol trinitrate reductase activity
SLIV_RS01440	COG4733	cellulase activity
SLIV_RS01490	COG1366	Belongs to the anti-sigma-factor antagonist family
SLIV_RS01520	COG4608	Belongs to the ABC transporter superfamily
SLIV_RS01525	COG0444	Belongs to the ABC transporter superfamily
SLIV_RS01530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLIV_RS01535	COG0601	transmembrane transport
SLIV_RS01540	COG4533	DNA binding
SLIV_RS01550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLIV_RS01570	COG0395	ABC-type sugar transport system, permease component
SLIV_RS01590	COG0604	alcohol dehydrogenase
SLIV_RS01595	COG1309	transcriptional regulator
SLIV_RS01605	COG0584	glycerophosphoryl diester phosphodiesterase
SLIV_RS01615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLIV_RS01620	COG3119	arylsulfatase activity
SLIV_RS01655	COG0516	GMP reductase activity
SLIV_RS01655	COG0517	IMP dehydrogenase activity
SLIV_RS01670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLIV_RS01675	COG2409	Drug exporters of the RND superfamily
SLIV_RS01685	COG2205	protein histidine kinase activity
SLIV_RS01690	COG0745	RESPONSE REGULATOR receiver
SLIV_RS01700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SLIV_RS01700	COG2755	lipolytic protein G-D-S-L family
SLIV_RS01740	COG0542	response to heat
SLIV_RS01745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLIV_RS01765	COG3226	Transcriptional regulator
SLIV_RS01770	COG2391	methyltransferase activity
SLIV_RS01775	COG0326	Molecular chaperone. Has ATPase activity
SLIV_RS01790	COG2755	lipolytic protein G-D-S-L family
SLIV_RS01795	COG4977	sequence-specific DNA binding
SLIV_RS01820	COG2175	clavaminate synthase activity
SLIV_RS01830	COG0395	ABC-type sugar transport system, permease component
SLIV_RS01835	COG1175	transmembrane transport
SLIV_RS01845	COG1609	Transcriptional regulator
SLIV_RS01850	COG3940	Belongs to the glycosyl hydrolase 43 family
SLIV_RS01855	COG1953	Uracil, thiamine, allantoin
SLIV_RS01895	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SLIV_RS01900	COG1082	Xylose isomerase domain protein TIM barrel
SLIV_RS01905	COG1063	alcohol dehydrogenase
SLIV_RS01920	COG0395	ABC-type sugar transport system, permease component
SLIV_RS01975	COG3415	Transposase
SLIV_RS01975	COG2801	Transposase and inactivated derivatives
SLIV_RS01980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLIV_RS01985	COG2151	metal-sulfur cluster biosynthetic enzyme
SLIV_RS01990	COG3396	Phenylacetate-CoA oxygenase
SLIV_RS01995	COG3460	Phenylacetate-CoA oxygenase
SLIV_RS02000	COG3396	Phenylacetate-CoA oxygenase
SLIV_RS02005	COG2050	protein possibly involved in aromatic compounds catabolism
SLIV_RS02050	COG5640	endopeptidase activity
SLIV_RS02060	COG1119	ATPase activity
SLIV_RS02080	COG1335	isochorismatase
SLIV_RS02135	COG2124	cytochrome p450
SLIV_RS02160	COG3340	Belongs to the peptidase S51 family
SLIV_RS02165	COG0583	DNA-binding transcription factor activity
SLIV_RS02180	COG2814	Major facilitator Superfamily
SLIV_RS02195	COG5640	endopeptidase activity
SLIV_RS02220	COG1959	2 iron, 2 sulfur cluster binding
SLIV_RS02230	COG2814	Major facilitator Superfamily
SLIV_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS02295	COG0028	Belongs to the TPP enzyme family
SLIV_RS02300	COG1609	Transcriptional regulator
SLIV_RS02305	COG4209	transmembrane transport
SLIV_RS02310	COG0395	ABC-type sugar transport system, permease component
SLIV_RS02330	COG0110	maltose O-acetyltransferase activity
SLIV_RS02355	COG1120	ATPase activity
SLIV_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS02430	COG0475	glutathione-regulated potassium exporter activity
SLIV_RS02470	COG0456	acetyltransferase
SLIV_RS02475	COG0243	molybdopterin cofactor binding
SLIV_RS02495	COG1088	dTDP-glucose 4,6-dehydratase activity
SLIV_RS02545	COG0009	L-threonylcarbamoyladenylate synthase
SLIV_RS02565	COG0656	L-ascorbic acid biosynthetic process
SLIV_RS02575	COG2208	phosphoserine phosphatase activity
SLIV_RS02595	COG2223	nitrite transmembrane transporter activity
SLIV_RS02610	COG1793	dna ligase
SLIV_RS02610	COG3285	dna ligase
SLIV_RS02620	COG0181	hydroxymethylbilane synthase activity
SLIV_RS02660	COG0366	Alpha amylase catalytic
SLIV_RS02675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLIV_RS02680	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLIV_RS02700	COG5002	protein histidine kinase activity
SLIV_RS02700	COG2205	protein histidine kinase activity
SLIV_RS02700	COG0784	Response regulator, receiver
SLIV_RS02715	COG1366	Belongs to the anti-sigma-factor antagonist family
SLIV_RS02720	COG1366	Belongs to the anti-sigma-factor antagonist family
SLIV_RS02725	COG2172	sigma factor antagonist activity
SLIV_RS02740	COG1252	NADH dehydrogenase
SLIV_RS02780	COG1982	Orn Lys Arg decarboxylase major
SLIV_RS02790	COG0477	Major facilitator Superfamily
SLIV_RS02830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLIV_RS02860	COG2197	response regulator
SLIV_RS02865	COG2340	Cysteine-rich secretory protein family
SLIV_RS02875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SLIV_RS02880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLIV_RS02880	COG0515	serine threonine protein kinase
SLIV_RS02885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLIV_RS02905	COG0667	Aldo Keto reductase
SLIV_RS02915	COG0328	RNA-DNA hybrid ribonuclease activity
SLIV_RS02930	COG0740	serine-type endopeptidase activity
SLIV_RS02935	COG0740	serine-type endopeptidase activity
SLIV_RS02940	COG1396	sequence-specific DNA binding
SLIV_RS02945	COG1191	sigma factor activity
SLIV_RS02980	COG0667	Aldo Keto reductase
SLIV_RS02985	COG0583	DNA-binding transcription factor activity
SLIV_RS02995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLIV_RS03000	COG0346	lactoylglutathione lyase activity
SLIV_RS03015	COG0667	Aldo Keto reductase
SLIV_RS03065	COG0673	inositol 2-dehydrogenase activity
SLIV_RS03115	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS03120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLIV_RS03135	COG0515	serine threonine protein kinase
SLIV_RS03155	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLIV_RS03165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SLIV_RS03180	COG2205	protein histidine kinase activity
SLIV_RS03185	COG0745	RESPONSE REGULATOR receiver
SLIV_RS03250	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SLIV_RS03255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLIV_RS03260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SLIV_RS03270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SLIV_RS03310	COG0596	Alpha beta hydrolase
SLIV_RS03345	COG1115	amino acid carrier protein
SLIV_RS03350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLIV_RS03370	COG2837	iron assimilation
SLIV_RS03395	COG1404	Belongs to the peptidase S8 family
SLIV_RS03465	COG1672	PFAM Archaeal ATPase
SLIV_RS03465	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLIV_RS03480	COG3507	Belongs to the glycosyl hydrolase 43 family
SLIV_RS03485	COG2186	Transcriptional regulator
SLIV_RS03495	COG1175	transmembrane transport
SLIV_RS03510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SLIV_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS03530	COG1289	transmembrane transporter activity
SLIV_RS03545	COG2807	transmembrane transport
SLIV_RS03560	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SLIV_RS03565	COG0477	Major facilitator Superfamily
SLIV_RS03595	COG0640	Transcriptional regulator
SLIV_RS03600	COG1846	Transcriptional regulator
SLIV_RS03605	COG1595	DNA-templated transcription, initiation
SLIV_RS03620	COG0778	Nitroreductase
SLIV_RS03640	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLIV_RS03640	COG1672	PFAM Archaeal ATPase
SLIV_RS03655	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLIV_RS03655	COG1672	PFAM Archaeal ATPase
SLIV_RS03685	COG0477	Major facilitator Superfamily
SLIV_RS03705	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLIV_RS03725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLIV_RS03765	COG1595	DNA-templated transcription, initiation
SLIV_RS03770	COG1764	response to oxidative stress
SLIV_RS03780	COG1053	succinate dehydrogenase
SLIV_RS03800	COG1595	DNA-templated transcription, initiation
SLIV_RS03855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLIV_RS03855	COG1017	nitric oxide dioxygenase activity
SLIV_RS03875	COG2409	Drug exporters of the RND superfamily
SLIV_RS03880	COG4585	Histidine kinase
SLIV_RS03885	COG2197	response regulator
SLIV_RS03895	COG0789	Transcriptional regulator
SLIV_RS03915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SLIV_RS03930	COG2409	Drug exporters of the RND superfamily
SLIV_RS03935	COG2205	protein histidine kinase activity
SLIV_RS03940	COG0745	RESPONSE REGULATOR receiver
SLIV_RS03950	COG2376	Dihydroxyacetone kinase
SLIV_RS03955	COG1461	Dihydroxyacetone kinase
SLIV_RS03985	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLIV_RS03985	COG1902	pentaerythritol trinitrate reductase activity
SLIV_RS04005	COG2890	protein-(glutamine-N5) methyltransferase activity
SLIV_RS04015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLIV_RS04030	COG3458	cephalosporin-C deacetylase activity
SLIV_RS04035	COG2188	Transcriptional regulator
SLIV_RS04040	COG2226	methyltransferase
SLIV_RS04045	COG1695	Transcriptional regulator
SLIV_RS04060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SLIV_RS04065	COG1686	Belongs to the peptidase S11 family
SLIV_RS04070	COG2066	Belongs to the glutaminase family
SLIV_RS04080	COG1968	undecaprenyl-diphosphatase activity
SLIV_RS04085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLIV_RS04090	COG1993	acr, cog1993
SLIV_RS04095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLIV_RS04100	COG0640	Transcriptional regulator
SLIV_RS04135	COG0137	argininosuccinate synthase activity
SLIV_RS04145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLIV_RS04160	COG1472	Belongs to the glycosyl hydrolase 3 family
SLIV_RS04170	COG1175	transmembrane transport
SLIV_RS04220	COG1874	Beta-galactosidase
SLIV_RS04220	COG0366	Alpha amylase catalytic
SLIV_RS04250	COG1653	transport
SLIV_RS04255	COG1175	transmembrane transport
SLIV_RS04260	COG0395	ABC-type sugar transport system, permease component
SLIV_RS04265	COG0366	Alpha amylase catalytic
SLIV_RS04275	COG1132	(ABC) transporter
SLIV_RS04295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLIV_RS04305	COG0531	amino acid
SLIV_RS04310	COG0668	transmembrane transport
SLIV_RS04315	COG2838	Isocitrate dehydrogenase
SLIV_RS04325	COG2124	cytochrome p450
SLIV_RS04350	COG2197	response regulator
SLIV_RS04370	COG0385	Bile acid
SLIV_RS04380	COG0673	inositol 2-dehydrogenase activity
SLIV_RS04390	COG1609	Transcriptional regulator
SLIV_RS04400	COG0673	inositol 2-dehydrogenase activity
SLIV_RS04430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLIV_RS04440	COG3718	enzyme involved in inositol metabolism
SLIV_RS04445	COG3962	Belongs to the TPP enzyme family
SLIV_RS04450	COG2188	Transcriptional regulator
SLIV_RS04485	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS04490	COG0183	Belongs to the thiolase family
SLIV_RS04495	COG2267	carboxylic ester hydrolase activity
SLIV_RS04520	COG0174	glutamine synthetase
SLIV_RS04535	COG1320	monovalent cation:proton antiporter activity
SLIV_RS04550	COG0651	ATP synthesis coupled electron transport
SLIV_RS04555	COG1006	Multisubunit Na H antiporter MnhC subunit
SLIV_RS04560	COG2111	Na H antiporter
SLIV_RS04560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLIV_RS04590	COG0583	DNA-binding transcription factor activity
SLIV_RS04595	COG0156	8-amino-7-oxononanoate synthase activity
SLIV_RS04600	COG1063	alcohol dehydrogenase
SLIV_RS04640	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS04650	COG1024	Enoyl-CoA hydratase
SLIV_RS04650	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLIV_RS04655	COG0183	Belongs to the thiolase family
SLIV_RS04660	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS04665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLIV_RS04670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLIV_RS04690	COG1309	transcriptional regulator
SLIV_RS04705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLIV_RS04720	COG2755	lipolytic protein G-D-S-L family
SLIV_RS04730	COG2365	Tyrosine phosphatase family
SLIV_RS04750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLIV_RS04755	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLIV_RS04770	COG1657	PFAM Prenyltransferase squalene oxidase
SLIV_RS04780	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLIV_RS04795	COG1562	ergosterol biosynthetic process
SLIV_RS04800	COG1134	teichoic acid transport
SLIV_RS04840	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLIV_RS04850	COG1024	Enoyl-CoA hydratase
SLIV_RS04870	COG2183	response to ionizing radiation
SLIV_RS04875	COG0488	(ABC) transporter
SLIV_RS04890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SLIV_RS04915	COG1113	amino acid transport
SLIV_RS04925	COG1024	Enoyl-CoA hydratase
SLIV_RS04925	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLIV_RS04930	COG0183	Belongs to the thiolase family
SLIV_RS04935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLIV_RS04940	COG3268	Saccharopine dehydrogenase
SLIV_RS04955	COG1515	deoxyribonuclease V activity
SLIV_RS04985	COG0488	(ABC) transporter
SLIV_RS04990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLIV_RS04995	COG1834	amidinotransferase
SLIV_RS05045	COG1793	dna ligase
SLIV_RS05055	COG1470	cell adhesion involved in biofilm formation
SLIV_RS05080	COG3485	protocatechuate 3,4-dioxygenase
SLIV_RS05085	COG3485	protocatechuate 3,4-dioxygenase
SLIV_RS05090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLIV_RS05095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLIV_RS05125	COG3511	phospholipase C
SLIV_RS05130	COG0477	Major facilitator Superfamily
SLIV_RS05155	COG2197	response regulator
SLIV_RS05160	COG1132	(ABC) transporter
SLIV_RS05165	COG1132	(ABC) transporter
SLIV_RS05175	COG0515	serine threonine protein kinase
SLIV_RS05220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLIV_RS05230	COG1486	melibiose metabolic process
SLIV_RS05240	COG4585	Histidine kinase
SLIV_RS05245	COG2197	response regulator
SLIV_RS05250	COG2409	Drug exporters of the RND superfamily
SLIV_RS05270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLIV_RS05285	COG0166	Belongs to the GPI family
SLIV_RS05290	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SLIV_RS05305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLIV_RS05320	COG0297	glycogen (starch) synthase activity
SLIV_RS05335	COG1183	phosphatidylcholine synthase activity
SLIV_RS05345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLIV_RS05350	COG0747	negative chemotaxis
SLIV_RS05395	COG0300	oxidoreductase activity
SLIV_RS05425	COG1733	regulation of RNA biosynthetic process
SLIV_RS05450	COG5434	Belongs to the glycosyl hydrolase 28 family
SLIV_RS05450	COG4632	Exopolysaccharide biosynthesis protein
SLIV_RS05465	COG2723	6-phospho-beta-galactosidase activity
SLIV_RS05470	COG0395	ABC-type sugar transport system, permease component
SLIV_RS05475	COG1175	transmembrane transport
SLIV_RS05480	COG2182	Extracellular solute-binding protein
SLIV_RS05540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLIV_RS05555	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS05565	COG0045	succinate-CoA ligase (ADP-forming) activity
SLIV_RS05575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLIV_RS05585	COG2223	nitrite transmembrane transporter activity
SLIV_RS05640	COG0673	inositol 2-dehydrogenase activity
SLIV_RS05650	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLIV_RS05655	COG1129	ABC transporter
SLIV_RS05670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLIV_RS05680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SLIV_RS05685	COG3383	formate dehydrogenase (NAD+) activity
SLIV_RS05690	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLIV_RS05700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SLIV_RS05725	COG0477	Major facilitator Superfamily
SLIV_RS05735	COG0656	L-ascorbic acid biosynthetic process
SLIV_RS05740	COG4221	oxidoreductase activity
SLIV_RS05745	COG2226	methyltransferase
SLIV_RS05750	COG5297	Belongs to the glycosyl hydrolase family 6
SLIV_RS05755	COG5297	Belongs to the glycosyl hydrolase family 6
SLIV_RS05755	COG4733	cellulase activity
SLIV_RS05775	COG3401	FG-GAP repeat protein
SLIV_RS05780	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SLIV_RS05780	COG4106	trans-aconitate 2-methyltransferase activity
SLIV_RS05785	COG2154	pterin-4-alpha-carbinolamine dehydratase
SLIV_RS05815	COG1140	nitrate reductase beta subunit
SLIV_RS05845	COG0531	amino acid
SLIV_RS05885	COG1191	sigma factor activity
SLIV_RS05900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLIV_RS05910	COG0693	protein deglycase activity
SLIV_RS05930	COG1597	lipid kinase activity
SLIV_RS05995	COG1793	dna ligase
SLIV_RS05995	COG3285	dna ligase
SLIV_RS06010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLIV_RS06040	COG1619	proteins homologs of microcin C7 resistance protein MccF
SLIV_RS06050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLIV_RS06055	COG2362	D-Aminopeptidase
SLIV_RS06065	COG1366	Belongs to the anti-sigma-factor antagonist family
SLIV_RS06065	COG2208	phosphoserine phosphatase activity
SLIV_RS06065	COG2172	sigma factor antagonist activity
SLIV_RS06090	COG0596	Alpha beta hydrolase
SLIV_RS06110	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLIV_RS06120	COG0604	alcohol dehydrogenase
SLIV_RS06125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLIV_RS06125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLIV_RS06130	COG2301	Belongs to the HpcH HpaI aldolase family
SLIV_RS06140	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS06145	COG0688	phosphatidylethanolamine metabolic process
SLIV_RS06155	COG1929	Belongs to the glycerate kinase type-1 family
SLIV_RS06165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SLIV_RS06175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLIV_RS06190	COG0640	Transcriptional regulator
SLIV_RS06210	COG1124	(ABC) transporter
SLIV_RS06215	COG0444	Belongs to the ABC transporter superfamily
SLIV_RS06220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLIV_RS06225	COG0601	transmembrane transport
SLIV_RS06235	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SLIV_RS06250	COG2249	NAD(P)H dehydrogenase (quinone) activity
SLIV_RS06260	COG0483	inositol monophosphate 1-phosphatase activity
SLIV_RS06270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLIV_RS06285	COG1891	lyase activity
SLIV_RS06290	COG1278	Cold shock
SLIV_RS06295	COG0019	diaminopimelate decarboxylase activity
SLIV_RS06305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLIV_RS06315	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLIV_RS06340	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLIV_RS06340	COG2308	Evidence 4 Homologs of previously reported genes of
SLIV_RS06355	COG1120	ATPase activity
SLIV_RS06365	COG4585	Histidine kinase
SLIV_RS06375	COG2197	response regulator
SLIV_RS06400	COG1953	Uracil, thiamine, allantoin
SLIV_RS06405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLIV_RS06410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLIV_RS06425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLIV_RS06445	COG0542	response to heat
SLIV_RS06450	COG0405	Gamma-glutamyltransferase
SLIV_RS06470	COG1609	Transcriptional regulator
SLIV_RS06475	COG0366	Alpha amylase catalytic
SLIV_RS06475	COG1470	cell adhesion involved in biofilm formation
SLIV_RS06490	COG0154	amidase activity
SLIV_RS06510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLIV_RS06525	COG0477	Major facilitator Superfamily
SLIV_RS06545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SLIV_RS06580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLIV_RS06670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLIV_RS06685	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLIV_RS06695	COG1472	Belongs to the glycosyl hydrolase 3 family
SLIV_RS06705	COG3246	L-lysine catabolic process to acetate
SLIV_RS06710	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLIV_RS06720	COG1132	(ABC) transporter
SLIV_RS06725	COG1802	Transcriptional regulator
SLIV_RS06730	COG3938	Belongs to the proline racemase family
SLIV_RS06735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLIV_RS06740	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLIV_RS06745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLIV_RS06745	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLIV_RS06750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLIV_RS06755	COG3629	intracellular signal transduction
SLIV_RS06775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLIV_RS06805	COG0477	Major facilitator Superfamily
SLIV_RS06810	COG0596	Alpha beta hydrolase
SLIV_RS06825	COG0604	alcohol dehydrogenase
SLIV_RS06825	COG3321	synthase
SLIV_RS06830	COG3321	synthase
SLIV_RS06830	COG0604	alcohol dehydrogenase
SLIV_RS06840	COG4770	biotin carboxylase activity
SLIV_RS06845	COG0674	pyruvate-flavodoxin oxidoreductase activity
SLIV_RS06845	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SLIV_RS06850	COG1013	pyruvate-flavodoxin oxidoreductase activity
SLIV_RS06860	COG0702	epimerase
SLIV_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS06885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLIV_RS06895	COG1940	carbohydrate kinase activity
SLIV_RS06915	COG2188	Transcriptional regulator
SLIV_RS06920	COG0673	inositol 2-dehydrogenase activity
SLIV_RS06925	COG2197	response regulator
SLIV_RS06940	COG0431	NADPH-dependent FMN reductase
SLIV_RS06950	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS06955	COG4266	Belongs to the allantoicase family
SLIV_RS06960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLIV_RS06965	COG1414	Transcriptional regulator
SLIV_RS06980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SLIV_RS07000	COG1595	DNA-templated transcription, initiation
SLIV_RS07030	COG1609	Transcriptional regulator
SLIV_RS07035	COG3250	beta-galactosidase activity
SLIV_RS07045	COG1175	transmembrane transport
SLIV_RS07050	COG3833	ABC-type maltose transport systems, permease component
SLIV_RS07065	COG4264	IucA IucC family
SLIV_RS07105	COG0406	alpha-ribazole phosphatase activity
SLIV_RS07120	COG2233	PERMEase
SLIV_RS07130	COG2233	PERMEase
SLIV_RS07140	COG2351	hydroxyisourate hydrolase activity
SLIV_RS07160	COG3622	Belongs to the hyi family
SLIV_RS07165	COG2084	Dehydrogenase
SLIV_RS07170	COG0753	catalase activity
SLIV_RS07185	COG3960	tartronate-semialdehyde synthase activity
SLIV_RS07210	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS07215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLIV_RS07220	COG2197	response regulator
SLIV_RS07255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SLIV_RS07255	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SLIV_RS07260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SLIV_RS07265	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS07275	COG0859	PFAM glycosyl transferase family 9
SLIV_RS07280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SLIV_RS07290	COG2192	nodulation
SLIV_RS07295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLIV_RS07300	COG0726	polysaccharide deacetylase
SLIV_RS07325	COG2252	PERMEase
SLIV_RS07330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLIV_RS07345	COG3835	regulator
SLIV_RS07375	COG3851	Histidine kinase
SLIV_RS07380	COG2197	response regulator
SLIV_RS07390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLIV_RS07395	COG1802	Transcriptional regulator
SLIV_RS07415	COG0028	Belongs to the TPP enzyme family
SLIV_RS07435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLIV_RS07445	COG1162	GTPase activity
SLIV_RS07455	COG0277	FAD linked oxidase domain protein
SLIV_RS07490	COG2197	response regulator
SLIV_RS07495	COG4585	Histidine kinase
SLIV_RS07505	COG2040	homocysteine
SLIV_RS07520	COG0714	Associated with various cellular activities
SLIV_RS07535	COG2027	D-alanyl-D-alanine carboxypeptidase
SLIV_RS07600	COG1917	Cupin 2, conserved barrel domain protein
SLIV_RS07600	COG4977	sequence-specific DNA binding
SLIV_RS07605	COG3142	Participates in the control of copper homeostasis
SLIV_RS07615	COG1940	carbohydrate kinase activity
SLIV_RS07615	COG1846	Transcriptional regulator
SLIV_RS07640	COG1940	carbohydrate kinase activity
SLIV_RS07660	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS07690	COG0175	sulfate reduction
SLIV_RS07695	COG0529	Catalyzes the synthesis of activated sulfate
SLIV_RS07715	COG1116	anion transmembrane transporter activity
SLIV_RS07720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLIV_RS07745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SLIV_RS07760	COG1175	transmembrane transport
SLIV_RS07805	COG3173	Aminoglycoside phosphotransferase
SLIV_RS07815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLIV_RS07835	COG1309	transcriptional regulator
SLIV_RS07865	COG1732	Glycine betaine
SLIV_RS07870	COG1174	glycine betaine transport
SLIV_RS07875	COG1174	glycine betaine transport
SLIV_RS07885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLIV_RS07890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SLIV_RS07925	COG0330	HflC and HflK could
SLIV_RS07935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLIV_RS07935	COG0723	plastoquinol--plastocyanin reductase activity
SLIV_RS07955	COG1116	anion transmembrane transporter activity
SLIV_RS07965	COG3220	belongs to the UPF0276 family
SLIV_RS07980	COG3253	May function as heme-dependent peroxidase
SLIV_RS07985	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLIV_RS07995	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLIV_RS08040	COG1472	Belongs to the glycosyl hydrolase 3 family
SLIV_RS08045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SLIV_RS08060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SLIV_RS08065	COG0183	Belongs to the thiolase family
SLIV_RS08070	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLIV_RS08070	COG1024	Enoyl-CoA hydratase
SLIV_RS08080	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS08085	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS08090	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS08095	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS08100	COG1316	TRANSCRIPTIONal
SLIV_RS08120	COG0531	amino acid
SLIV_RS08125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLIV_RS08130	COG3979	chitinase
SLIV_RS08135	COG4214	carbohydrate transport
SLIV_RS08145	COG4213	ABC transporter substrate-binding protein
SLIV_RS08150	COG1940	carbohydrate kinase activity
SLIV_RS08155	COG0395	ABC-type sugar transport system, permease component
SLIV_RS08160	COG1175	transmembrane transport
SLIV_RS08165	COG1653	transport
SLIV_RS08195	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SLIV_RS08200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLIV_RS08205	COG1760	l-serine dehydratase
SLIV_RS08275	COG2801	Transposase and inactivated derivatives
SLIV_RS08535	COG1011	Hydrolase
SLIV_RS08565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLIV_RS08585	COG2226	methyltransferase
SLIV_RS08600	COG2192	nodulation
SLIV_RS08605	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SLIV_RS08635	COG1324	tolerance protein
SLIV_RS08700	COG0785	Cytochrome C biogenesis protein
SLIV_RS08705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SLIV_RS08705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SLIV_RS08775	COG1024	Enoyl-CoA hydratase
SLIV_RS08785	COG0531	amino acid
SLIV_RS08790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SLIV_RS08795	COG2235	arginine
SLIV_RS08805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SLIV_RS08835	COG1799	cell septum assembly
SLIV_RS08840	COG0247	lactate metabolic process
SLIV_RS08840	COG0277	FAD linked oxidase domain protein
SLIV_RS08855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SLIV_RS08860	COG0789	Transcriptional regulator
SLIV_RS08865	COG0310	cobalt ion transport
SLIV_RS08870	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
SLIV_RS08880	COG1122	ATPase activity
SLIV_RS08885	COG0477	Major facilitator Superfamily
SLIV_RS08905	COG2319	Wd-40 repeat
SLIV_RS08940	COG3619	membrane
SLIV_RS08945	COG0405	Gamma-glutamyltransferase
SLIV_RS08955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SLIV_RS08965	COG0436	Aminotransferase
SLIV_RS08970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SLIV_RS09005	COG3693	PFAM glycoside hydrolase, family 10
SLIV_RS09030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SLIV_RS09040	COG1178	ABC-type Fe3 transport system permease component
SLIV_RS09045	COG3842	ATPase activity
SLIV_RS09050	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS09055	COG1278	Cold shock
SLIV_RS09060	COG0513	Belongs to the DEAD box helicase family
SLIV_RS09100	COG3291	Pkd domain containing protein
SLIV_RS09135	COG2409	Drug exporters of the RND superfamily
SLIV_RS09145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SLIV_RS09150	COG0531	amino acid
SLIV_RS09175	COG0500	methyltransferase
SLIV_RS09185	COG1088	dTDP-glucose 4,6-dehydratase activity
SLIV_RS09190	COG3321	synthase
SLIV_RS09190	COG0604	alcohol dehydrogenase
SLIV_RS09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLIV_RS09200	COG0156	8-amino-7-oxononanoate synthase activity
SLIV_RS09205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS09210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLIV_RS09215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS09225	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLIV_RS09255	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS09270	COG0569	domain protein
SLIV_RS09300	COG1136	(ABC) transporter
SLIV_RS09300	COG4591	ABC-type transport system involved in lipoprotein release permease component
SLIV_RS09310	COG0756	dUTP diphosphatase activity
SLIV_RS09335	COG2205	protein histidine kinase activity
SLIV_RS09340	COG0745	RESPONSE REGULATOR receiver
SLIV_RS09350	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SLIV_RS09400	COG2222	sugar isomerase
SLIV_RS09410	COG2188	Transcriptional regulator
SLIV_RS09420	COG1435	thymidine kinase activity
SLIV_RS09440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLIV_RS09445	COG1802	Transcriptional regulator
SLIV_RS09460	COG0612	Peptidase, M16
SLIV_RS09465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLIV_RS09485	COG0372	Belongs to the citrate synthase family
SLIV_RS09500	COG3290	protein histidine kinase activity
SLIV_RS09505	COG4565	transcriptional regulatory protein
SLIV_RS09510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLIV_RS09520	COG2197	response regulator
SLIV_RS09535	COG0187	DNA topoisomerase II activity
SLIV_RS09550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLIV_RS09555	COG2186	Transcriptional regulator
SLIV_RS09575	COG0514	ATP-dependent DNA helicase (RecQ)
SLIV_RS09590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SLIV_RS09625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SLIV_RS09630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SLIV_RS09635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SLIV_RS09670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SLIV_RS09680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLIV_RS09685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SLIV_RS09695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SLIV_RS09715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLIV_RS09725	COG2197	response regulator
SLIV_RS09730	COG3851	Histidine kinase
SLIV_RS09755	COG2205	protein histidine kinase activity
SLIV_RS09760	COG0745	RESPONSE REGULATOR receiver
SLIV_RS09765	COG1126	abc transporter atp-binding protein
SLIV_RS09770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLIV_RS09775	COG0765	amino acid transport
SLIV_RS09780	COG0765	amino acid transport
SLIV_RS09795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SLIV_RS09805	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SLIV_RS09815	COG0628	permease
SLIV_RS09840	COG1917	Cupin 2, conserved barrel domain protein
SLIV_RS09840	COG2207	Transcriptional regulator
SLIV_RS09845	COG1201	RNA secondary structure unwinding
SLIV_RS09850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLIV_RS09870	COG0783	Belongs to the Dps family
SLIV_RS09875	COG1396	sequence-specific DNA binding
SLIV_RS09880	COG1058	Belongs to the CinA family
SLIV_RS09880	COG1546	Belongs to the CinA family
SLIV_RS09890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLIV_RS09900	COG1674	ftsk spoiiie
SLIV_RS09910	COG2205	protein histidine kinase activity
SLIV_RS09910	COG0784	Response regulator, receiver
SLIV_RS09915	COG2208	phosphoserine phosphatase activity
SLIV_RS09915	COG2770	Histidine kinase
SLIV_RS09945	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SLIV_RS09950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLIV_RS09955	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SLIV_RS09975	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SLIV_RS09980	COG0612	Peptidase, M16
SLIV_RS09985	COG1185	polyribonucleotide nucleotidyltransferase activity
SLIV_RS09990	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SLIV_RS10005	COG1674	ftsk spoiiie
SLIV_RS10020	COG1404	Belongs to the peptidase S8 family
SLIV_RS10055	COG3266	domain, Protein
SLIV_RS10070	COG0455	bacterial-type flagellum organization
SLIV_RS10075	COG0747	negative chemotaxis
SLIV_RS10080	COG0601	transmembrane transport
SLIV_RS10095	COG4608	Belongs to the ABC transporter superfamily
SLIV_RS10110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SLIV_RS10115	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SLIV_RS10125	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SLIV_RS10140	COG0779	Required for maturation of 30S ribosomal subunits
SLIV_RS10160	COG0442	prolyl-tRNA aminoacylation
SLIV_RS10175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLIV_RS10180	COG0750	zinc metalloprotease
SLIV_RS10185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SLIV_RS10215	COG0395	ABC-type sugar transport system, permease component
SLIV_RS10220	COG4209	transmembrane transport
SLIV_RS10235	COG2197	response regulator
SLIV_RS10260	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS10265	COG2508	Transcriptional regulator
SLIV_RS10265	COG2508	Transcriptional regulator
SLIV_RS10300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLIV_RS10305	COG1177	transmembrane transport
SLIV_RS10310	COG1176	ABC-type spermidine putrescine transport system, permease component I
SLIV_RS10315	COG3842	ATPase activity
SLIV_RS10345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLIV_RS10350	COG0584	glycerophosphoryl diester phosphodiesterase
SLIV_RS10370	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS10380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLIV_RS10415	COG3842	ATPase activity
SLIV_RS10420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SLIV_RS10430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SLIV_RS10435	COG3629	intracellular signal transduction
SLIV_RS10435	COG3903	Transcriptional regulator
SLIV_RS10440	COG0575	Belongs to the CDS family
SLIV_RS10445	COG0233	cytoplasmic translational termination
SLIV_RS10450	COG0528	UMP kinase activity
SLIV_RS10455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SLIV_RS10460	COG0052	Belongs to the universal ribosomal protein uS2 family
SLIV_RS10475	COG1191	sigma factor activity
SLIV_RS10490	COG0792	nuclease activity
SLIV_RS10505	COG0681	Belongs to the peptidase S26 family
SLIV_RS10510	COG0681	Belongs to the peptidase S26 family
SLIV_RS10515	COG0681	Belongs to the peptidase S26 family
SLIV_RS10520	COG0335	large ribosomal subunit rRNA binding
SLIV_RS10525	COG0336	Belongs to the RNA methyltransferase TrmD family
SLIV_RS10530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SLIV_RS10535	COG1837	Belongs to the UPF0109 family
SLIV_RS10560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLIV_RS10570	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SLIV_RS10605	COG0477	Major facilitator Superfamily
SLIV_RS10610	COG1196	nuclear chromosome segregation
SLIV_RS10620	COG1254	Belongs to the acylphosphatase family
SLIV_RS10630	COG1733	regulation of RNA biosynthetic process
SLIV_RS10635	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLIV_RS10640	COG0571	ribonuclease III activity
SLIV_RS10645	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SLIV_RS10660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SLIV_RS10665	COG0742	ribosomal rna small subunit methyltransferase
SLIV_RS10675	COG1461	Dihydroxyacetone kinase
SLIV_RS10680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLIV_RS10685	COG0351	phosphomethylpyrimidine kinase
SLIV_RS10700	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLIV_RS10705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SLIV_RS10715	COG1920	GTP binding
SLIV_RS10725	COG0776	regulation of translation
SLIV_RS10735	COG0066	3-isopropylmalate dehydratase activity
SLIV_RS10740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SLIV_RS10745	COG1414	Transcriptional regulator
SLIV_RS10795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SLIV_RS10800	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLIV_RS10810	COG5002	protein histidine kinase activity
SLIV_RS10815	COG2018	Roadblock/LC7 domain
SLIV_RS10835	COG2018	Roadblock/LC7 domain
SLIV_RS10855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLIV_RS10865	COG2353	YceI-like domain
SLIV_RS10885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLIV_RS10895	COG2957	Belongs to the agmatine deiminase family
SLIV_RS10900	COG0804	urea catabolic process
SLIV_RS10905	COG0832	Belongs to the urease beta subunit family
SLIV_RS10905	COG0831	urea catabolic process
SLIV_RS10915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SLIV_RS10920	COG0473	3-isopropylmalate dehydrogenase activity
SLIV_RS10930	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS10935	COG0506	proline dehydrogenase activity
SLIV_RS10940	COG2508	Transcriptional regulator
SLIV_RS10950	COG0477	Major facilitator Superfamily
SLIV_RS10955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLIV_RS10960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SLIV_RS10965	COG0440	acetolactate synthase activity
SLIV_RS10975	COG5001	Diguanylate cyclase
SLIV_RS10985	COG0667	Aldo Keto reductase
SLIV_RS10990	COG2133	pyrroloquinoline quinone binding
SLIV_RS11000	COG2197	response regulator
SLIV_RS11015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLIV_RS11020	COG2409	Drug exporters of the RND superfamily
SLIV_RS11025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLIV_RS11035	COG0154	amidase activity
SLIV_RS11040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLIV_RS11060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLIV_RS11070	COG4221	oxidoreductase activity
SLIV_RS11075	COG1611	Belongs to the LOG family
SLIV_RS11090	COG0482	sulfurtransferase activity
SLIV_RS11125	COG2860	membrane
SLIV_RS11130	COG4608	Belongs to the ABC transporter superfamily
SLIV_RS11135	COG0444	Belongs to the ABC transporter superfamily
SLIV_RS11145	COG4166	transmembrane transport
SLIV_RS11150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLIV_RS11170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLIV_RS11175	COG0509	glycine decarboxylation via glycine cleavage system
SLIV_RS11180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLIV_RS11185	COG1760	l-serine dehydratase
SLIV_RS11190	COG0477	Major facilitator Superfamily
SLIV_RS11200	COG3757	hydrolase, family 25
SLIV_RS11200	COG3409	Peptidoglycan-binding domain 1 protein
SLIV_RS11205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLIV_RS11215	COG0789	Transcriptional regulator
SLIV_RS11240	COG1376	ErfK ybiS ycfS ynhG family protein
SLIV_RS11255	COG2197	response regulator
SLIV_RS11260	COG4585	Histidine kinase
SLIV_RS11270	COG1131	(ABC) transporter
SLIV_RS11275	COG1132	(ABC) transporter
SLIV_RS11280	COG1132	(ABC) transporter
SLIV_RS11285	COG2274	protein secretion by the type I secretion system
SLIV_RS11290	COG1132	(ABC) transporter
SLIV_RS11310	COG0058	SHG alpha-glucan phosphorylase activity
SLIV_RS11315	COG0366	Alpha amylase catalytic
SLIV_RS11320	COG0366	Alpha amylase catalytic
SLIV_RS11325	COG3281	Trehalose synthase
SLIV_RS11330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLIV_RS11340	COG0492	ferredoxin-NADP+ reductase activity
SLIV_RS11340	COG3118	belongs to the thioredoxin family
SLIV_RS11350	COG1301	dicarboxylic acid transport
SLIV_RS11355	COG3290	protein histidine kinase activity
SLIV_RS11360	COG4565	transcriptional regulatory protein
SLIV_RS11365	COG3903	Transcriptional regulator
SLIV_RS11365	COG3629	intracellular signal transduction
SLIV_RS11385	COG1653	transport
SLIV_RS11395	COG0395	ABC-type sugar transport system, permease component
SLIV_RS11405	COG0205	6-phosphofructokinase activity
SLIV_RS11410	COG0857	belongs to the CobB CobQ family
SLIV_RS11410	COG0280	phosphate acetyltransferase
SLIV_RS11415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SLIV_RS11455	COG4977	sequence-specific DNA binding
SLIV_RS11460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLIV_RS11460	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLIV_RS11510	COG0745	RESPONSE REGULATOR receiver
SLIV_RS11530	COG0183	Belongs to the thiolase family
SLIV_RS11550	COG1131	(ABC) transporter
SLIV_RS11585	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SLIV_RS11600	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLIV_RS11635	COG4585	Histidine kinase
SLIV_RS11640	COG2197	response regulator
SLIV_RS11655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SLIV_RS11660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SLIV_RS11665	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SLIV_RS11670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SLIV_RS11675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLIV_RS11680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SLIV_RS11685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLIV_RS11705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLIV_RS11710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLIV_RS11720	COG2890	protein-(glutamine-N5) methyltransferase activity
SLIV_RS11725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SLIV_RS11730	COG0254	rRNA binding
SLIV_RS11735	COG1316	TRANSCRIPTIONal
SLIV_RS11745	COG0083	homoserine kinase activity
SLIV_RS11750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SLIV_RS11755	COG0460	homoserine dehydrogenase
SLIV_RS11760	COG0019	diaminopimelate decarboxylase activity
SLIV_RS11765	COG0018	arginyl-trna synthetase
SLIV_RS11770	COG0745	RESPONSE REGULATOR receiver
SLIV_RS11800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLIV_RS11805	COG2329	Antibiotic biosynthesis monooxygenase
SLIV_RS11810	COG0662	Cupin 2, conserved barrel domain protein
SLIV_RS11815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLIV_RS11820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLIV_RS11825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS11830	COG2867	negative regulation of translational initiation
SLIV_RS11845	COG3467	pyridoxamine 5'-phosphate
SLIV_RS11860	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SLIV_RS11865	COG3285	dna ligase
SLIV_RS11865	COG1793	dna ligase
SLIV_RS11885	COG2205	protein histidine kinase activity
SLIV_RS11925	COG0791	NLP P60 protein
SLIV_RS11925	COG3883	PFAM NLP P60 protein
SLIV_RS11970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SLIV_RS11980	COG0745	RESPONSE REGULATOR receiver
SLIV_RS11985	COG2205	protein histidine kinase activity
SLIV_RS11990	COG0567	Dehydrogenase, E1 component
SLIV_RS11990	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLIV_RS12010	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SLIV_RS12090	COG0604	alcohol dehydrogenase
SLIV_RS12095	COG0281	malic enzyme
SLIV_RS12110	COG1126	abc transporter atp-binding protein
SLIV_RS12115	COG4106	trans-aconitate 2-methyltransferase activity
SLIV_RS12150	COG0142	geranyltranstransferase activity
SLIV_RS12155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLIV_RS12195	COG1597	lipid kinase activity
SLIV_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS12220	COG0363	glucosamine-6-phosphate deaminase activity
SLIV_RS12225	COG1472	Belongs to the glycosyl hydrolase 3 family
SLIV_RS12230	COG0395	ABC-type sugar transport system, permease component
SLIV_RS12235	COG1175	transmembrane transport
SLIV_RS12240	COG2182	Extracellular solute-binding protein
SLIV_RS12245	COG2188	Transcriptional regulator
SLIV_RS12290	COG2124	cytochrome p450
SLIV_RS12300	COG0242	peptide deformylase activity
SLIV_RS12320	COG5662	AntiSigma factor
SLIV_RS12325	COG1595	DNA-templated transcription, initiation
SLIV_RS12335	COG2135	peptidase activity
SLIV_RS12345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SLIV_RS12355	COG2076	Multidrug Resistance protein
SLIV_RS12365	COG0483	inositol monophosphate 1-phosphatase activity
SLIV_RS12395	COG1615	UPF0182 protein
SLIV_RS12405	COG3480	Lon protease (S16) C-terminal proteolytic domain
SLIV_RS12455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SLIV_RS12485	COG2816	NAD+ diphosphatase activity
SLIV_RS12495	COG0210	DNA helicase
SLIV_RS12520	COG0596	Alpha beta hydrolase
SLIV_RS12595	COG1432	Conserved Protein
SLIV_RS12605	COG2095	MarC family integral membrane protein
SLIV_RS12610	COG0613	PHP domain protein
SLIV_RS12620	COG2814	Major facilitator Superfamily
SLIV_RS12630	COG0598	Magnesium transport protein CorA
SLIV_RS12640	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SLIV_RS12665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLIV_RS12670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLIV_RS12680	COG1595	DNA-templated transcription, initiation
SLIV_RS12690	COG1024	Enoyl-CoA hydratase
SLIV_RS12695	COG0519	Catalyzes the synthesis of GMP from XMP
SLIV_RS12705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SLIV_RS12715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLIV_RS12750	COG2197	response regulator
SLIV_RS12755	COG4585	Histidine kinase
SLIV_RS12765	COG1131	(ABC) transporter
SLIV_RS12785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLIV_RS12810	COG4608	Belongs to the ABC transporter superfamily
SLIV_RS12815	COG0444	Belongs to the ABC transporter superfamily
SLIV_RS12820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLIV_RS12825	COG0601	transmembrane transport
SLIV_RS12835	COG4608	Belongs to the ABC transporter superfamily
SLIV_RS12840	COG0444	Belongs to the ABC transporter superfamily
SLIV_RS12850	COG4166	transmembrane transport
SLIV_RS12855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLIV_RS12860	COG1217	gtp-binding protein TYPA
SLIV_RS12885	COG1053	succinate dehydrogenase
SLIV_RS12890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SLIV_RS12935	COG0300	oxidoreductase activity
SLIV_RS12940	COG0583	DNA-binding transcription factor activity
SLIV_RS12955	COG2318	DinB family
SLIV_RS12960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SLIV_RS12970	COG2867	negative regulation of translational initiation
SLIV_RS12975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS12980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLIV_RS12985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLIV_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS12995	COG3629	intracellular signal transduction
SLIV_RS13000	COG2409	Drug exporters of the RND superfamily
SLIV_RS13005	COG0477	Major facilitator Superfamily
SLIV_RS13040	COG0477	Major facilitator Superfamily
SLIV_RS13060	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLIV_RS13075	COG0604	alcohol dehydrogenase
SLIV_RS13090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLIV_RS13100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLIV_RS13115	COG0012	GTP binding
SLIV_RS13130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SLIV_RS13140	COG1570	exodeoxyribonuclease VII activity
SLIV_RS13145	COG1722	exodeoxyribonuclease VII activity
SLIV_RS13175	COG0778	Nitroreductase
SLIV_RS13200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SLIV_RS13200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SLIV_RS13210	COG0114	fumarate hydratase activity
SLIV_RS13225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLIV_RS13245	COG1136	(ABC) transporter
SLIV_RS13260	COG0450	alkyl hydroperoxide reductase
SLIV_RS13265	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLIV_RS13275	COG0741	lytic transglycosylase activity
SLIV_RS13280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SLIV_RS13290	COG2226	methyltransferase
SLIV_RS13390	COG2894	cell division
SLIV_RS13470	COG2610	gluconate transmembrane transporter activity
SLIV_RS13475	COG0251	oxidation-reduction process
SLIV_RS13480	COG1414	Transcriptional regulator
SLIV_RS13495	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SLIV_RS13505	COG0436	Aminotransferase
SLIV_RS13530	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SLIV_RS13540	COG1309	transcriptional regulator
SLIV_RS13550	COG1331	Highly conserved protein containing a thioredoxin domain
SLIV_RS13555	COG0590	tRNA wobble adenosine to inosine editing
SLIV_RS13565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLIV_RS13585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLIV_RS13595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SLIV_RS13610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SLIV_RS13615	COG2255	four-way junction helicase activity
SLIV_RS13620	COG1595	DNA-templated transcription, initiation
SLIV_RS13640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLIV_RS13665	COG0667	Aldo Keto reductase
SLIV_RS13675	COG1090	epimerase
SLIV_RS13680	COG1064	alcohol dehydrogenase
SLIV_RS13690	COG0667	Aldo Keto reductase
SLIV_RS13695	COG1309	transcriptional regulator
SLIV_RS13710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SLIV_RS13715	COG1595	DNA-templated transcription, initiation
SLIV_RS13725	COG1136	(ABC) transporter
SLIV_RS13750	COG2986	histidine ammonia-lyase
SLIV_RS13760	COG1024	Enoyl-CoA hydratase
SLIV_RS13770	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLIV_RS13780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLIV_RS13795	COG0424	maF-like protein
SLIV_RS13805	COG4770	biotin carboxylase activity
SLIV_RS13830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLIV_RS13845	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS13850	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS13855	COG0515	serine threonine protein kinase
SLIV_RS13870	COG1595	DNA-templated transcription, initiation
SLIV_RS13875	COG0745	RESPONSE REGULATOR receiver
SLIV_RS13880	COG2205	protein histidine kinase activity
SLIV_RS13905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLIV_RS13925	COG0583	DNA-binding transcription factor activity
SLIV_RS13930	COG2814	Major facilitator Superfamily
SLIV_RS13970	COG1079	Belongs to the binding-protein-dependent transport system permease family
SLIV_RS13980	COG3845	ABC transporter
SLIV_RS13985	COG1744	ABC transporter substrate-binding protein PnrA-like
SLIV_RS13990	COG1744	ABC transporter substrate-binding protein PnrA-like
SLIV_RS13995	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLIV_RS13995	COG1473	amidohydrolase
SLIV_RS14005	COG2089	acid synthase
SLIV_RS14020	COG1216	Glycosyl transferase, family 2
SLIV_RS14035	COG0463	Glycosyl transferase, family 2
SLIV_RS14065	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLIV_RS14065	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLIV_RS14080	COG1595	DNA-templated transcription, initiation
SLIV_RS14090	COG1595	DNA-templated transcription, initiation
SLIV_RS14120	COG2009	succinate dehydrogenase
SLIV_RS14130	COG1053	succinate dehydrogenase
SLIV_RS14160	COG1309	transcriptional regulator
SLIV_RS14165	COG1408	metallophosphoesterase
SLIV_RS14175	COG1686	Belongs to the peptidase S11 family
SLIV_RS14180	COG1295	ribonuclease BN
SLIV_RS14195	COG0671	phosphoesterase, PA-phosphatase related
SLIV_RS14215	COG0180	Tryptophanyl-tRNA synthetase
SLIV_RS14225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLIV_RS14230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLIV_RS14235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLIV_RS14240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLIV_RS14260	COG4175	Glycine betaine
SLIV_RS14260	COG0517	IMP dehydrogenase activity
SLIV_RS14270	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS14275	COG0039	L-malate dehydrogenase activity
SLIV_RS14290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SLIV_RS14325	COG3409	Peptidoglycan-binding domain 1 protein
SLIV_RS14335	COG0138	bifunctional purine biosynthesis protein purh
SLIV_RS14365	COG0045	succinate-CoA ligase (ADP-forming) activity
SLIV_RS14375	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SLIV_RS14380	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SLIV_RS14385	COG0714	Associated with various cellular activities
SLIV_RS14400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLIV_RS14400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLIV_RS14410	COG0739	heme binding
SLIV_RS14440	COG2197	response regulator
SLIV_RS14480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SLIV_RS14480	COG0519	Catalyzes the synthesis of GMP from XMP
SLIV_RS14505	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS14510	COG0515	serine threonine protein kinase
SLIV_RS14520	COG0515	serine threonine protein kinase
SLIV_RS14525	COG2815	serine threonine protein kinase
SLIV_RS14525	COG0515	serine threonine protein kinase
SLIV_RS14545	COG0516	GMP reductase activity
SLIV_RS14555	COG1595	DNA-templated transcription, initiation
SLIV_RS14570	COG0583	DNA-binding transcription factor activity
SLIV_RS14580	COG4221	oxidoreductase activity
SLIV_RS14590	COG0459	protein refolding
SLIV_RS14595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SLIV_RS14600	COG0726	polysaccharide deacetylase
SLIV_RS14605	COG0726	polysaccharide deacetylase
SLIV_RS14615	COG4941	Belongs to the sigma-70 factor family
SLIV_RS14625	COG1316	TRANSCRIPTIONal
SLIV_RS14640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SLIV_RS14650	COG0456	acetyltransferase
SLIV_RS14650	COG1214	PFAM Peptidase M22, glycoprotease
SLIV_RS14665	COG0802	atpase or kinase
SLIV_RS14675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SLIV_RS14680	COG0736	holo-[acyl-carrier-protein] synthase activity
SLIV_RS14700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLIV_RS14710	COG1072	(Pantothenic acid kinase))
SLIV_RS14720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLIV_RS14725	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SLIV_RS14730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SLIV_RS14745	COG0101	tRNA pseudouridine synthase activity
SLIV_RS14750	COG0203	ribosomal protein L17
SLIV_RS14755	COG0202	RNA polymerase activity
SLIV_RS14760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SLIV_RS14765	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SLIV_RS14770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SLIV_RS14775	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SLIV_RS14785	COG0563	adenylate kinase activity
SLIV_RS14790	COG0201	protein transport
SLIV_RS14795	COG0200	Binds to the 23S rRNA
SLIV_RS14800	COG1841	ribosomal large subunit assembly
SLIV_RS14805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SLIV_RS14810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SLIV_RS14815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SLIV_RS14820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SLIV_RS14825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLIV_RS14830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SLIV_RS14835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SLIV_RS14840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SLIV_RS14845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SLIV_RS14850	COG0255	Belongs to the universal ribosomal protein uL29 family
SLIV_RS14855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SLIV_RS14860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SLIV_RS14865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SLIV_RS14870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SLIV_RS14875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SLIV_RS14880	COG0089	rRNA binding
SLIV_RS14885	COG0088	Forms part of the polypeptide exit tunnel
SLIV_RS14890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SLIV_RS14895	COG0051	transcription antitermination factor activity, RNA binding
SLIV_RS14950	COG0513	Belongs to the DEAD box helicase family
SLIV_RS14955	COG1278	Cold shock
SLIV_RS14960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SLIV_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS15035	COG2197	response regulator
SLIV_RS15045	COG3415	Transposase
SLIV_RS15045	COG2801	Transposase and inactivated derivatives
SLIV_RS15050	COG0577	efflux transmembrane transporter activity
SLIV_RS15050	COG1136	(ABC) transporter
SLIV_RS15065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLIV_RS15070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLIV_RS15075	COG0049	tRNA binding
SLIV_RS15080	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SLIV_RS15085	COG0463	Glycosyl transferase, family 2
SLIV_RS15100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SLIV_RS15105	COG0085	RNA polymerase activity
SLIV_RS15110	COG0222	ribosome binding
SLIV_RS15115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SLIV_RS15130	COG0081	regulation of translation
SLIV_RS15135	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SLIV_RS15140	COG0250	Participates in transcription elongation, termination and antitermination
SLIV_RS15145	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SLIV_RS15155	COG0436	Aminotransferase
SLIV_RS15160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLIV_RS15165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SLIV_RS15175	COG0477	Major facilitator Superfamily
SLIV_RS15200	COG2030	dehydratase
SLIV_RS15205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLIV_RS15220	COG0402	S-adenosylhomocysteine deaminase activity
SLIV_RS15225	COG0702	epimerase
SLIV_RS15230	COG3903	Transcriptional regulator
SLIV_RS15230	COG3629	intracellular signal transduction
SLIV_RS15240	COG1666	GTP binding
SLIV_RS15245	COG2261	transglycosylase associated protein
SLIV_RS15260	COG3304	Inner membrane component domain
SLIV_RS15265	COG0501	Belongs to the peptidase M48B family
SLIV_RS15270	COG1007	ATP synthesis coupled electron transport
SLIV_RS15285	COG0713	ATP synthesis coupled electron transport
SLIV_RS15295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLIV_RS15300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLIV_RS15305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLIV_RS15310	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLIV_RS15315	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLIV_RS15320	COG4585	Histidine kinase
SLIV_RS15335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SLIV_RS15335	COG0674	pyruvate-flavodoxin oxidoreductase activity
SLIV_RS15340	COG1013	pyruvate-flavodoxin oxidoreductase activity
SLIV_RS15345	COG0702	epimerase
SLIV_RS15375	COG0655	NAD(P)H dehydrogenase (quinone) activity
SLIV_RS15385	COG1131	(ABC) transporter
SLIV_RS15395	COG0142	geranyltranstransferase activity
SLIV_RS15405	COG0561	phosphatase activity
SLIV_RS15420	COG0514	ATP-dependent DNA helicase (RecQ)
SLIV_RS15430	COG1007	ATP synthesis coupled electron transport
SLIV_RS15440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLIV_RS15445	COG0713	ATP synthesis coupled electron transport
SLIV_RS15450	COG0839	Belongs to the complex I subunit 6 family
SLIV_RS15455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLIV_RS15460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLIV_RS15465	COG1034	ATP synthesis coupled electron transport
SLIV_RS15470	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLIV_RS15480	COG0649	NAD binding
SLIV_RS15485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLIV_RS15490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLIV_RS15505	COG0242	peptide deformylase activity
SLIV_RS15525	COG2226	methyltransferase
SLIV_RS15555	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLIV_RS15655	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
SLIV_RS15775	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLIV_RS15775	COG0515	serine threonine protein kinase
SLIV_RS15780	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLIV_RS15785	COG1278	Cold shock
SLIV_RS15800	COG0183	Belongs to the thiolase family
SLIV_RS15815	COG1309	transcriptional regulator
SLIV_RS15820	COG1301	dicarboxylic acid transport
SLIV_RS15835	COG1573	uracil-dna glycosylase
SLIV_RS15840	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLIV_RS15850	COG0163	prenyltransferase activity
SLIV_RS15855	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SLIV_RS15860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SLIV_RS15870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLIV_RS15870	COG0515	serine threonine protein kinase
SLIV_RS15900	COG0583	DNA-binding transcription factor activity
SLIV_RS15935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SLIV_RS15940	COG1333	cytochrome c biogenesis protein
SLIV_RS15945	COG0785	Cytochrome C biogenesis protein
SLIV_RS15950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLIV_RS15960	COG0406	alpha-ribazole phosphatase activity
SLIV_RS15965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SLIV_RS16000	COG1302	Protein conserved in bacteria
SLIV_RS16025	COG0582	viral genome integration into host DNA
SLIV_RS16085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SLIV_RS16090	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLIV_RS16100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SLIV_RS16145	COG1535	isochorismatase
SLIV_RS16145	COG3433	isochorismatase activity
SLIV_RS16150	COG0738	Major facilitator superfamily
SLIV_RS16155	COG3226	Transcriptional regulator
SLIV_RS16200	COG3795	YCII-related domain
SLIV_RS16205	COG4941	Belongs to the sigma-70 factor family
SLIV_RS16210	COG0477	Major facilitator Superfamily
SLIV_RS16215	COG1309	transcriptional regulator
SLIV_RS16220	COG4257	antibiotic catabolic process
SLIV_RS16245	COG0386	Belongs to the glutathione peroxidase family
SLIV_RS16270	COG1686	Belongs to the peptidase S11 family
SLIV_RS16325	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLIV_RS16340	COG3629	intracellular signal transduction
SLIV_RS16340	COG3903	Transcriptional regulator
SLIV_RS16355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLIV_RS16355	COG0515	serine threonine protein kinase
SLIV_RS16365	COG1309	transcriptional regulator
SLIV_RS16375	COG0259	pyridoxamine-phosphate oxidase activity
SLIV_RS16385	COG2072	flavoprotein involved in K transport
SLIV_RS16395	COG2271	Major facilitator Superfamily
SLIV_RS16420	COG1595	DNA-templated transcription, initiation
SLIV_RS16490	COG0596	Alpha beta hydrolase
SLIV_RS16490	COG2945	thiolester hydrolase activity
SLIV_RS16500	COG4821	SIS domain
SLIV_RS16510	COG1733	regulation of RNA biosynthetic process
SLIV_RS16530	COG0259	pyridoxamine-phosphate oxidase activity
SLIV_RS16550	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS16565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLIV_RS16580	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLIV_RS16580	COG0515	serine threonine protein kinase
SLIV_RS16610	COG2318	DinB family
SLIV_RS16625	COG0247	lactate metabolic process
SLIV_RS16625	COG0277	FAD linked oxidase domain protein
SLIV_RS16630	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SLIV_RS16640	COG2197	response regulator
SLIV_RS16690	COG0667	Aldo Keto reductase
SLIV_RS16730	COG0667	Aldo Keto reductase
SLIV_RS16755	COG2252	PERMEase
SLIV_RS16765	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLIV_RS16780	COG2814	Major facilitator Superfamily
SLIV_RS16790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SLIV_RS16795	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLIV_RS16800	COG1278	Cold shock
SLIV_RS16835	COG1061	Type III restriction enzyme res subunit
SLIV_RS16845	COG3973	AAA domain
SLIV_RS16890	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SLIV_RS16905	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS16910	COG1309	transcriptional regulator
SLIV_RS16945	COG0459	protein refolding
SLIV_RS16950	COG1278	Cold shock
SLIV_RS16965	COG0463	Glycosyl transferase, family 2
SLIV_RS16975	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SLIV_RS17000	COG1940	carbohydrate kinase activity
SLIV_RS17010	COG1105	Belongs to the carbohydrate kinase PfkB family
SLIV_RS17035	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SLIV_RS17045	COG2197	response regulator
SLIV_RS17065	COG0494	nUDIX hydrolase
SLIV_RS17075	COG1309	transcriptional regulator
SLIV_RS17110	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLIV_RS17110	COG1672	PFAM Archaeal ATPase
SLIV_RS17130	COG0464	growth
SLIV_RS17225	COG3842	ATPase activity
SLIV_RS17250	COG0215	cysteine-tRNA ligase activity
SLIV_RS17255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SLIV_RS17260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SLIV_RS17265	COG1329	Transcriptional regulator
SLIV_RS17280	COG5002	protein histidine kinase activity
SLIV_RS17305	COG2207	Transcriptional regulator
SLIV_RS17305	COG3708	Transcriptional regulator
SLIV_RS17355	COG0588	phosphoglycerate mutase activity
SLIV_RS17380	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS17420	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SLIV_RS17445	COG0546	phosphoglycolate phosphatase activity
SLIV_RS17450	COG2188	Transcriptional regulator
SLIV_RS17460	COG2188	Transcriptional regulator
SLIV_RS17470	COG4552	Acetyltransferase involved in intracellular survival and related
SLIV_RS17485	COG1490	D-aminoacyl-tRNA deacylase activity
SLIV_RS17490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLIV_RS17495	COG0735	belongs to the Fur family
SLIV_RS17500	COG3485	protocatechuate 3,4-dioxygenase
SLIV_RS17600	COG0745	RESPONSE REGULATOR receiver
SLIV_RS17605	COG1609	Transcriptional regulator
SLIV_RS17610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLIV_RS17615	COG0745	RESPONSE REGULATOR receiver
SLIV_RS17630	COG1733	regulation of RNA biosynthetic process
SLIV_RS17635	COG0737	Belongs to the 5'-nucleotidase family
SLIV_RS17640	COG0456	acetyltransferase
SLIV_RS17670	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SLIV_RS17680	COG0494	nUDIX hydrolase
SLIV_RS17680	COG0406	alpha-ribazole phosphatase activity
SLIV_RS17700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SLIV_RS17705	COG0306	phosphate transporter
SLIV_RS17715	COG1937	Protein conserved in bacteria
SLIV_RS17725	COG0277	FAD linked oxidase domain protein
SLIV_RS17730	COG0671	phosphoesterase, PA-phosphatase related
SLIV_RS17735	COG0741	lytic transglycosylase activity
SLIV_RS17735	COG0739	heme binding
SLIV_RS17735	COG1196	nuclear chromosome segregation
SLIV_RS17775	COG4585	Histidine kinase
SLIV_RS17780	COG2197	response regulator
SLIV_RS17815	COG1252	NADH dehydrogenase
SLIV_RS17845	COG0579	oxidoreductase
SLIV_RS17855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SLIV_RS17885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SLIV_RS17885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SLIV_RS17890	COG2860	membrane
SLIV_RS17920	COG0110	maltose O-acetyltransferase activity
SLIV_RS17935	COG0513	Belongs to the DEAD box helicase family
SLIV_RS17970	COG1643	Atp-dependent helicase
SLIV_RS17990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SLIV_RS18000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SLIV_RS18040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLIV_RS18045	COG0047	phosphoribosylformylglycinamidine synthase activity
SLIV_RS18050	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLIV_RS18085	COG2197	response regulator
SLIV_RS18095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SLIV_RS18110	COG0151	Belongs to the GarS family
SLIV_RS18135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLIV_RS18210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SLIV_RS18245	COG1191	sigma factor activity
SLIV_RS18250	COG1191	sigma factor activity
SLIV_RS18265	COG0477	Major facilitator Superfamily
SLIV_RS18290	COG3467	pyridoxamine 5'-phosphate
SLIV_RS18300	COG0477	Major facilitator Superfamily
SLIV_RS18305	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLIV_RS18315	COG2205	protein histidine kinase activity
SLIV_RS18320	COG0745	RESPONSE REGULATOR receiver
SLIV_RS18350	COG1733	regulation of RNA biosynthetic process
SLIV_RS18355	COG0768	penicillin binding
SLIV_RS18385	COG0784	Response regulator, receiver
SLIV_RS18390	COG1309	transcriptional regulator
SLIV_RS18395	COG2814	Major facilitator Superfamily
SLIV_RS18400	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS18405	COG1595	DNA-templated transcription, initiation
SLIV_RS18435	COG1309	transcriptional regulator
SLIV_RS18445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLIV_RS18460	COG0653	protein targeting
SLIV_RS18480	COG0006	proline dipeptidase activity
SLIV_RS18500	COG1999	signal sequence binding
SLIV_RS18515	COG2837	iron assimilation
SLIV_RS18520	COG0077	Prephenate dehydratase
SLIV_RS18525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SLIV_RS18530	COG0561	phosphatase activity
SLIV_RS18550	COG1131	(ABC) transporter
SLIV_RS18565	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SLIV_RS18580	COG0561	phosphatase activity
SLIV_RS18585	COG0739	heme binding
SLIV_RS18595	COG4988	ABC transporter
SLIV_RS18600	COG1294	oxidase, subunit
SLIV_RS18605	COG1271	oxidase subunit
SLIV_RS18610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLIV_RS18615	COG1609	Transcriptional regulator
SLIV_RS18640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SLIV_RS18665	COG0662	Cupin 2, conserved barrel domain protein
SLIV_RS18670	COG1950	PFAM Membrane protein of
SLIV_RS18675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLIV_RS18680	COG0626	cystathionine gamma-synthase activity
SLIV_RS18705	COG2814	Major facilitator Superfamily
SLIV_RS18725	COG0305	Participates in initiation and elongation during chromosome replication
SLIV_RS18735	COG0359	binds to the 23S rRNA
SLIV_RS18740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLIV_RS18745	COG0629	single-stranded DNA binding
SLIV_RS18750	COG0360	Binds together with S18 to 16S ribosomal RNA
SLIV_RS18775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLIV_RS18800	COG0617	tRNA 3'-terminal CCA addition
SLIV_RS18820	COG1595	DNA-templated transcription, initiation
SLIV_RS18830	COG0492	ferredoxin-NADP+ reductase activity
SLIV_RS18835	COG3118	belongs to the thioredoxin family
SLIV_RS18850	COG1192	Involved in chromosome partitioning
SLIV_RS18855	COG0357	Ribosomal RNA small subunit methyltransferase G
SLIV_RS18865	COG0706	membrane insertase activity
SLIV_RS18870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SLIV_RS18875	COG0594	ribonuclease P activity
SLIV_RS18880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SLIV_RS18885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SLIV_RS18890	COG0592	DNA-directed DNA polymerase activity
SLIV_RS18895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SLIV_RS18900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SLIV_RS18905	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SLIV_RS18910	COG0187	DNA topoisomerase II activity
SLIV_RS18915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLIV_RS18945	COG2319	Wd-40 repeat
SLIV_RS18945	COG4249	Peptidase C14 caspase catalytic subunit p20
SLIV_RS18945	COG2319	Wd-40 repeat
SLIV_RS18945	COG4249	Peptidase C14 caspase catalytic subunit p20
SLIV_RS18985	COG0515	serine threonine protein kinase
SLIV_RS19000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLIV_RS19015	COG0705	Rhomboid family
SLIV_RS19040	COG3764	Sortase (surface protein transpeptidase)
SLIV_RS19045	COG3764	Sortase (surface protein transpeptidase)
SLIV_RS19050	COG0515	serine threonine protein kinase
SLIV_RS19055	COG0768	penicillin binding
SLIV_RS19070	COG1716	ATPase activity
SLIV_RS19075	COG1716	ATPase activity
SLIV_RS19125	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLIV_RS19130	COG1309	transcriptional regulator
SLIV_RS19135	COG1522	sequence-specific DNA binding
SLIV_RS19180	COG0604	alcohol dehydrogenase
SLIV_RS19180	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS19180	COG3321	synthase
SLIV_RS19195	COG0515	serine threonine protein kinase
SLIV_RS19200	COG0515	serine threonine protein kinase
SLIV_RS19220	COG0022	dehydrogenase e1 component
SLIV_RS19225	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLIV_RS19310	COG1362	aminopeptidase activity
SLIV_RS19315	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS19325	COG1741	Belongs to the pirin family
SLIV_RS19340	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SLIV_RS19345	COG1215	transferase activity, transferring glycosyl groups
SLIV_RS19355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLIV_RS19415	COG0366	Alpha amylase catalytic
SLIV_RS19420	COG1957	nucleoside hydrolase
SLIV_RS19425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLIV_RS19530	COG3239	Fatty acid desaturase
SLIV_RS19535	COG4585	Histidine kinase
SLIV_RS19540	COG2197	response regulator
SLIV_RS19545	COG0577	efflux transmembrane transporter activity
SLIV_RS19545	COG1136	(ABC) transporter
SLIV_RS19560	COG1136	(ABC) transporter
SLIV_RS19560	COG0577	efflux transmembrane transporter activity
SLIV_RS19570	COG4585	Histidine kinase
SLIV_RS19580	COG1278	Cold shock
SLIV_RS19600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLIV_RS19615	COG0745	RESPONSE REGULATOR receiver
SLIV_RS19620	COG5002	protein histidine kinase activity
SLIV_RS19625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SLIV_RS19660	COG0513	Belongs to the DEAD box helicase family
SLIV_RS19665	COG1278	Cold shock
SLIV_RS19670	COG0667	Aldo Keto reductase
SLIV_RS19715	COG0288	reversible hydration of carbon dioxide
SLIV_RS19725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SLIV_RS19730	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SLIV_RS19735	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SLIV_RS19740	COG1595	DNA-templated transcription, initiation
SLIV_RS19745	COG1252	NADH dehydrogenase
SLIV_RS19805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLIV_RS19810	COG0640	Transcriptional regulator
SLIV_RS19815	COG0798	PFAM Bile acid sodium symporter
SLIV_RS19820	COG2072	flavoprotein involved in K transport
SLIV_RS19825	COG0640	Transcriptional regulator
SLIV_RS19860	COG0596	Alpha beta hydrolase
SLIV_RS19915	COG0717	Belongs to the dCTP deaminase family
SLIV_RS19920	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SLIV_RS19940	COG0247	lactate metabolic process
SLIV_RS19940	COG2181	nitrate reductase activity
SLIV_RS19945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLIV_RS19950	COG0443	Heat shock 70 kDa protein
SLIV_RS19955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SLIV_RS19960	COG0484	heat shock protein binding
SLIV_RS19965	COG0789	Transcriptional regulator
SLIV_RS19970	COG4213	ABC transporter substrate-binding protein
SLIV_RS20000	COG0542	response to heat
SLIV_RS20025	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SLIV_RS20030	COG4585	Histidine kinase
SLIV_RS20035	COG2197	response regulator
SLIV_RS20050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SLIV_RS20055	COG0191	fructose-bisphosphate aldolase activity
SLIV_RS20060	COG0477	Major facilitator Superfamily
SLIV_RS20075	COG3844	kynureninase activity
SLIV_RS20095	COG4585	Histidine kinase
SLIV_RS20100	COG2197	response regulator
SLIV_RS20105	COG4585	Histidine kinase
SLIV_RS20110	COG2197	response regulator
SLIV_RS20120	COG2124	cytochrome p450
SLIV_RS20135	COG3559	Exporter of polyketide antibiotics
SLIV_RS20140	COG1131	(ABC) transporter
SLIV_RS20160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SLIV_RS20190	COG1802	Transcriptional regulator
SLIV_RS20195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLIV_RS20210	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SLIV_RS20215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SLIV_RS20240	COG1595	DNA-templated transcription, initiation
SLIV_RS20265	COG1585	Membrane protein implicated in regulation of membrane protease activity
SLIV_RS20270	COG2268	Band 7 protein
SLIV_RS20290	COG3263	regulation of cellular component size
SLIV_RS20295	COG0475	glutathione-regulated potassium exporter activity
SLIV_RS20325	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SLIV_RS20330	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLIV_RS20355	COG0745	RESPONSE REGULATOR receiver
SLIV_RS20360	COG2205	protein histidine kinase activity
SLIV_RS20390	COG1408	metallophosphoesterase
SLIV_RS20400	COG4499	WXG100 protein secretion system (Wss), protein YukC
SLIV_RS20400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLIV_RS20410	COG0003	Pfam Anion-transporting ATPase
SLIV_RS20430	COG0596	Alpha beta hydrolase
SLIV_RS20440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLIV_RS20455	COG0494	nUDIX hydrolase
SLIV_RS20465	COG0596	Alpha beta hydrolase
SLIV_RS20475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SLIV_RS20480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLIV_RS20485	COG0659	secondary active sulfate transmembrane transporter activity
SLIV_RS20545	COG1111	helicase
SLIV_RS20545	COG1205	dead DEAH box helicase
SLIV_RS20550	COG1366	Belongs to the anti-sigma-factor antagonist family
SLIV_RS20555	COG2172	sigma factor antagonist activity
SLIV_RS20560	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SLIV_RS20580	COG1754	DNA topoisomerase type I activity
SLIV_RS20580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SLIV_RS20585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SLIV_RS20590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SLIV_RS20605	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS20610	COG0583	DNA-binding transcription factor activity
SLIV_RS20615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLIV_RS20615	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLIV_RS20640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLIV_RS20645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLIV_RS20650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLIV_RS20655	COG0254	rRNA binding
SLIV_RS20665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLIV_RS20690	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS20710	COG0076	glutamate decarboxylase activity
SLIV_RS20725	COG0789	Transcriptional regulator
SLIV_RS20730	COG0393	Putative heavy-metal-binding
SLIV_RS20735	COG0586	Pfam SNARE associated Golgi protein
SLIV_RS20745	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SLIV_RS20750	COG2027	D-alanyl-D-alanine carboxypeptidase
SLIV_RS20760	COG0037	tRNA processing
SLIV_RS20775	COG0302	gtp cyclohydrolase
SLIV_RS20790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SLIV_RS20805	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SLIV_RS20805	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SLIV_RS20830	COG0649	NAD binding
SLIV_RS20850	COG1660	Displays ATPase and GTPase activities
SLIV_RS20875	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SLIV_RS20880	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SLIV_RS20890	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SLIV_RS20910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SLIV_RS20950	COG0739	heme binding
SLIV_RS21000	COG2205	protein histidine kinase activity
SLIV_RS21005	COG0745	RESPONSE REGULATOR receiver
SLIV_RS21015	COG1595	DNA-templated transcription, initiation
SLIV_RS21020	COG1194	a g-specific adenine glycosylase
SLIV_RS21030	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SLIV_RS21050	COG0248	Ppx GppA phosphatase
SLIV_RS21055	COG1082	Xylose isomerase domain protein TIM barrel
SLIV_RS21065	COG0129	dihydroxy-acid dehydratase activity
SLIV_RS21070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLIV_RS21070	COG0515	serine threonine protein kinase
SLIV_RS21095	COG1129	ABC transporter
SLIV_RS21095	COG0842	Transport permease protein
SLIV_RS21105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SLIV_RS21110	COG1335	isochorismatase
SLIV_RS21120	COG0180	Tryptophanyl-tRNA synthetase
SLIV_RS21140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLIV_RS21150	COG2223	nitrite transmembrane transporter activity
SLIV_RS21155	COG0123	including yeast histone deacetylase and acetoin utilization protein
SLIV_RS21205	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SLIV_RS21210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SLIV_RS21215	COG0181	hydroxymethylbilane synthase activity
SLIV_RS21220	COG1648	precorrin-2 dehydrogenase activity
SLIV_RS21220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SLIV_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS21235	COG0604	alcohol dehydrogenase
SLIV_RS21235	COG3321	synthase
SLIV_RS21250	COG0113	porphobilinogen synthase activity
SLIV_RS21270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLIV_RS21275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SLIV_RS21280	COG0018	arginyl-trna synthetase
SLIV_RS21285	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SLIV_RS21305	COG1690	Belongs to the RtcB family
SLIV_RS21315	COG1742	UPF0060 membrane protein
SLIV_RS21320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLIV_RS21380	COG1366	Belongs to the anti-sigma-factor antagonist family
SLIV_RS21380	COG2172	sigma factor antagonist activity
SLIV_RS21380	COG2208	phosphoserine phosphatase activity
SLIV_RS21405	COG0569	domain protein
SLIV_RS21405	COG0475	glutathione-regulated potassium exporter activity
SLIV_RS21415	COG0659	secondary active sulfate transmembrane transporter activity
SLIV_RS21420	COG0789	Transcriptional regulator
SLIV_RS21450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS21455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLIV_RS21465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLIV_RS21485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SLIV_RS21515	COG2175	clavaminate synthase activity
SLIV_RS21520	COG1132	(ABC) transporter
SLIV_RS21525	COG0510	thiamine kinase activity
SLIV_RS21535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLIV_RS21540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLIV_RS21565	COG2197	response regulator
SLIV_RS21570	COG4585	Histidine kinase
SLIV_RS21610	COG3629	intracellular signal transduction
SLIV_RS21610	COG3903	Transcriptional regulator
SLIV_RS21615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLIV_RS21625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SLIV_RS21630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SLIV_RS21630	COG0512	Glutamine amidotransferase of anthranilate synthase
SLIV_RS21635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SLIV_RS21640	COG0134	indole-3-glycerol-phosphate synthase activity
SLIV_RS21645	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SLIV_RS21650	COG1414	Transcriptional regulator
SLIV_RS21670	COG1846	Transcriptional regulator
SLIV_RS21675	COG3384	dioxygenase
SLIV_RS21680	COG1247	-acetyltransferase
SLIV_RS21685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLIV_RS21700	COG0477	Major facilitator Superfamily
SLIV_RS21705	COG1349	DNA-binding transcription factor activity
SLIV_RS21715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SLIV_RS21715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SLIV_RS21715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLIV_RS21755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SLIV_RS21780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SLIV_RS21785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLIV_RS21795	COG0315	cyclic pyranopterin monophosphate synthase activity
SLIV_RS21800	COG0315	cyclic pyranopterin monophosphate synthase activity
SLIV_RS21800	COG0521	Mo-molybdopterin cofactor biosynthetic process
SLIV_RS21805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLIV_RS21830	COG0708	Exodeoxyribonuclease III
SLIV_RS21840	COG2072	flavoprotein involved in K transport
SLIV_RS21845	COG2267	carboxylic ester hydrolase activity
SLIV_RS21860	COG4946	Tricorn protease homolog
SLIV_RS21860	COG0793	Belongs to the peptidase S41A family
SLIV_RS21870	COG2409	Drug exporters of the RND superfamily
SLIV_RS21875	COG0442	prolyl-tRNA aminoacylation
SLIV_RS21890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLIV_RS21895	COG1122	ATPase activity
SLIV_RS21905	COG0310	cobalt ion transport
SLIV_RS21915	COG0768	penicillin binding
SLIV_RS21945	COG0084	hydrolase, TatD family'
SLIV_RS21955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SLIV_RS21960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SLIV_RS21965	COG0488	(ABC) transporter
SLIV_RS22005	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SLIV_RS22015	COG2197	response regulator
SLIV_RS22025	COG4106	trans-aconitate 2-methyltransferase activity
SLIV_RS22035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLIV_RS22040	COG1309	transcriptional regulator
SLIV_RS22050	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SLIV_RS22060	COG0193	aminoacyl-tRNA hydrolase activity
SLIV_RS22065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SLIV_RS22070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLIV_RS22075	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SLIV_RS22090	COG4585	Histidine kinase
SLIV_RS22130	COG1136	(ABC) transporter
SLIV_RS22135	COG0577	efflux transmembrane transporter activity
SLIV_RS22205	COG0148	phosphopyruvate hydratase activity
SLIV_RS22225	COG1252	NADH dehydrogenase
SLIV_RS22230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLIV_RS22235	COG0577	efflux transmembrane transporter activity
SLIV_RS22235	COG1136	(ABC) transporter
SLIV_RS22240	COG1136	(ABC) transporter
SLIV_RS22295	COG0183	Belongs to the thiolase family
SLIV_RS22300	COG2755	lipolytic protein G-D-S-L family
SLIV_RS22325	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SLIV_RS22330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLIV_RS22340	COG1228	amidohydrolase
SLIV_RS22350	COG1191	sigma factor activity
SLIV_RS22355	COG1366	Belongs to the anti-sigma-factor antagonist family
SLIV_RS22370	COG3104	oligopeptide transport
SLIV_RS22375	COG0745	RESPONSE REGULATOR receiver
SLIV_RS22380	COG2205	protein histidine kinase activity
SLIV_RS22430	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLIV_RS22450	COG1316	TRANSCRIPTIONal
SLIV_RS22455	COG1316	TRANSCRIPTIONal
SLIV_RS22460	COG1316	TRANSCRIPTIONal
SLIV_RS22465	COG1316	TRANSCRIPTIONal
SLIV_RS22470	COG1316	TRANSCRIPTIONal
SLIV_RS22475	COG1316	TRANSCRIPTIONal
SLIV_RS22480	COG1316	TRANSCRIPTIONal
SLIV_RS22505	COG0778	Nitroreductase
SLIV_RS22505	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SLIV_RS22510	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLIV_RS22545	COG1620	l-lactate permease
SLIV_RS22550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLIV_RS22555	COG2835	tetraacyldisaccharide 4'-kinase activity
SLIV_RS22565	COG1482	cell wall glycoprotein biosynthetic process
SLIV_RS22575	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SLIV_RS22615	COG0714	Associated with various cellular activities
SLIV_RS22635	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SLIV_RS22640	COG0745	RESPONSE REGULATOR receiver
SLIV_RS22645	COG5002	protein histidine kinase activity
SLIV_RS22645	COG5000	phosphorelay sensor kinase activity
SLIV_RS22650	COG0823	Involved in the tonB-independent uptake of proteins
SLIV_RS22660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SLIV_RS22665	COG2197	response regulator
SLIV_RS22670	COG3214	Protein conserved in bacteria
SLIV_RS22680	COG0653	protein targeting
SLIV_RS22710	COG2902	Dehydrogenase
SLIV_RS22715	COG1216	Glycosyl transferase, family 2
SLIV_RS22715	COG1442	glycosyl transferase family 8
SLIV_RS22720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLIV_RS22725	COG1134	teichoic acid transport
SLIV_RS22770	COG1846	Transcriptional regulator
SLIV_RS22775	COG1764	response to oxidative stress
SLIV_RS22790	COG1216	Glycosyl transferase, family 2
SLIV_RS22795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLIV_RS22805	COG0395	ABC-type sugar transport system, permease component
SLIV_RS22810	COG1175	transmembrane transport
SLIV_RS22835	COG0515	serine threonine protein kinase
SLIV_RS22840	COG0515	serine threonine protein kinase
SLIV_RS22845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SLIV_RS22860	COG2884	Cell division ATP-binding protein ftsE
SLIV_RS22870	COG0793	Belongs to the peptidase S41A family
SLIV_RS22875	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SLIV_RS22885	COG0583	DNA-binding transcription factor activity
SLIV_RS22910	COG2223	nitrite transmembrane transporter activity
SLIV_RS22940	COG3973	AAA domain
SLIV_RS22950	COG0776	regulation of translation
SLIV_RS22955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLIV_RS22960	COG1678	Uncharacterized ACR, COG1678
SLIV_RS22975	COG1175	transmembrane transport
SLIV_RS22980	COG0395	ABC-type sugar transport system, permease component
SLIV_RS22985	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLIV_RS23000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLIV_RS23010	COG0667	Aldo Keto reductase
SLIV_RS23030	COG3480	Lon protease (S16) C-terminal proteolytic domain
SLIV_RS23040	COG1174	glycine betaine transport
SLIV_RS23050	COG1174	glycine betaine transport
SLIV_RS23065	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SLIV_RS23075	COG0277	FAD linked oxidase domain protein
SLIV_RS23090	COG1714	RDD family
SLIV_RS23110	COG1335	isochorismatase
SLIV_RS23120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SLIV_RS23130	COG1113	amino acid transport
SLIV_RS23155	COG1234	tRNA 3'-trailer cleavage
SLIV_RS23160	COG1263	PTS System
SLIV_RS23165	COG1263	PTS System
SLIV_RS23170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SLIV_RS23175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SLIV_RS23185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SLIV_RS23215	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SLIV_RS23230	COG4555	ABC transporter
SLIV_RS23245	COG2733	membrane
SLIV_RS23270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLIV_RS23315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLIV_RS23330	COG0456	acetyltransferase
SLIV_RS23335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLIV_RS23415	COG4702	Belongs to the UPF0303 family
SLIV_RS23420	COG0673	inositol 2-dehydrogenase activity
SLIV_RS23430	COG2188	Transcriptional regulator
SLIV_RS23450	COG0583	DNA-binding transcription factor activity
SLIV_RS23490	COG3397	chitin binding
SLIV_RS23505	COG1126	abc transporter atp-binding protein
SLIV_RS23510	COG0765	amino acid transport
SLIV_RS23515	COG0765	amino acid transport
SLIV_RS23520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLIV_RS23540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLIV_RS23580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLIV_RS23590	COG4106	trans-aconitate 2-methyltransferase activity
SLIV_RS23595	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SLIV_RS23605	COG0640	Transcriptional regulator
SLIV_RS23645	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SLIV_RS23655	COG0745	RESPONSE REGULATOR receiver
SLIV_RS23665	COG3509	depolymerase
SLIV_RS23665	COG3693	PFAM glycoside hydrolase, family 10
SLIV_RS23675	COG0395	ABC-type sugar transport system, permease component
SLIV_RS23700	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SLIV_RS23705	COG4977	sequence-specific DNA binding
SLIV_RS23715	COG0589	response to stress
SLIV_RS23720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLIV_RS23750	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLIV_RS23770	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS23785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLIV_RS23790	COG1309	transcriptional regulator
SLIV_RS23800	COG1946	Acyl-CoA thioesterase
SLIV_RS23820	COG3960	tartronate-semialdehyde synthase activity
SLIV_RS23835	COG2356	endonuclease I
SLIV_RS23870	COG1472	Belongs to the glycosyl hydrolase 3 family
SLIV_RS23900	COG0673	inositol 2-dehydrogenase activity
SLIV_RS23915	COG1869	D-ribose catabolic process
SLIV_RS23920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLIV_RS23925	COG1879	ABC-type sugar transport system periplasmic component
SLIV_RS23930	COG1129	ABC transporter
SLIV_RS23950	COG1595	DNA-templated transcription, initiation
SLIV_RS23975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SLIV_RS23990	COG0583	DNA-binding transcription factor activity
SLIV_RS24015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLIV_RS24045	COG1131	(ABC) transporter
SLIV_RS24060	COG1022	Amp-dependent synthetase and ligase
SLIV_RS24105	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS24125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SLIV_RS24130	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS24160	COG2304	oxidoreductase activity
SLIV_RS24175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLIV_RS24180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLIV_RS24190	COG2175	clavaminate synthase activity
SLIV_RS24220	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLIV_RS24245	COG0629	single-stranded DNA binding
SLIV_RS24255	COG3903	Transcriptional regulator
SLIV_RS24255	COG3629	intracellular signal transduction
SLIV_RS24290	COG0577	efflux transmembrane transporter activity
SLIV_RS24290	COG1136	(ABC) transporter
SLIV_RS24310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLIV_RS24330	COG0515	serine threonine protein kinase
SLIV_RS24340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLIV_RS24355	COG1486	melibiose metabolic process
SLIV_RS24360	COG0395	ABC-type sugar transport system, permease component
SLIV_RS24365	COG1175	transmembrane transport
SLIV_RS24370	COG1653	transport
SLIV_RS24380	COG0668	transmembrane transport
SLIV_RS24400	COG1959	2 iron, 2 sulfur cluster binding
SLIV_RS24405	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS24425	COG1846	Transcriptional regulator
SLIV_RS24430	COG0697	spore germination
SLIV_RS24490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SLIV_RS24495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SLIV_RS24500	COG1113	amino acid transport
SLIV_RS24505	COG1268	BioY protein
SLIV_RS24510	COG1113	amino acid transport
SLIV_RS24525	COG4552	Acetyltransferase involved in intracellular survival and related
SLIV_RS24540	COG3594	Acyltransferase
SLIV_RS24560	COG0544	peptidyl-prolyl cis-trans isomerase activity
SLIV_RS24565	COG0740	serine-type endopeptidase activity
SLIV_RS24570	COG0740	serine-type endopeptidase activity
SLIV_RS24575	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SLIV_RS24585	COG0525	valine-tRNA ligase activity
SLIV_RS24590	COG0285	dihydrofolate synthase activity
SLIV_RS24600	COG0105	UTP biosynthetic process
SLIV_RS24605	COG1077	Cell shape determining protein MreB Mrl
SLIV_RS24620	COG0768	penicillin binding
SLIV_RS24625	COG0772	Belongs to the SEDS family
SLIV_RS24675	COG1530	ribonuclease E activity
SLIV_RS24680	COG0371	Dehydrogenase
SLIV_RS24685	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SLIV_RS24690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SLIV_RS24695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SLIV_RS24700	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS24710	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS24720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLIV_RS24725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SLIV_RS24735	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SLIV_RS24745	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SLIV_RS24760	COG0501	Belongs to the peptidase M48B family
SLIV_RS24775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SLIV_RS24785	COG0799	negative regulation of ribosome biogenesis
SLIV_RS24790	COG0406	alpha-ribazole phosphatase activity
SLIV_RS24810	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLIV_RS24820	COG0495	leucyl-tRNA aminoacylation
SLIV_RS24830	COG1307	EDD domain protein, DegV family
SLIV_RS24835	COG1555	photosystem II stabilization
SLIV_RS24840	COG1234	tRNA 3'-trailer cleavage
SLIV_RS24845	COG2353	YceI-like domain
SLIV_RS24860	COG0268	Binds directly to 16S ribosomal RNA
SLIV_RS24865	COG0481	GTPase activity
SLIV_RS24900	COG1420	regulation of RNA biosynthetic process
SLIV_RS24905	COG0484	heat shock protein binding
SLIV_RS24930	COG4946	Tricorn protease homolog
SLIV_RS24930	COG0793	Belongs to the peptidase S41A family
SLIV_RS24935	COG0537	adenosine 5'-monophosphoramidase activity
SLIV_RS24940	COG1234	tRNA 3'-trailer cleavage
SLIV_RS24945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLIV_RS24960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLIV_RS24965	COG4948	Mandelate Racemase Muconate Lactonizing
SLIV_RS24975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLIV_RS24980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SLIV_RS25000	COG2315	Protein conserved in bacteria
SLIV_RS25010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SLIV_RS25035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLIV_RS25080	COG2409	Drug exporters of the RND superfamily
SLIV_RS25090	COG2197	response regulator
SLIV_RS25125	COG1381	Involved in DNA repair and RecF pathway recombination
SLIV_RS25130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLIV_RS25140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLIV_RS25145	COG1121	(ABC) transporter
SLIV_RS25150	COG0803	Belongs to the bacterial solute-binding protein 9 family
SLIV_RS25150	COG3443	Belongs to the bacterial solute-binding protein 9 family
SLIV_RS25155	COG0423	glycine-tRNA ligase activity
SLIV_RS25165	COG0477	Major facilitator Superfamily
SLIV_RS25180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLIV_RS25205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLIV_RS25205	COG0574	Belongs to the PEP-utilizing enzyme family
SLIV_RS25210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SLIV_RS25225	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS25230	COG1309	transcriptional regulator
SLIV_RS25240	COG2146	nitrite reductase [NAD(P)H] activity
SLIV_RS25240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLIV_RS25295	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS25300	COG0583	DNA-binding transcription factor activity
SLIV_RS25310	COG0243	molybdopterin cofactor binding
SLIV_RS25325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SLIV_RS25335	COG0358	DNA primase activity
SLIV_RS25350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLIV_RS25365	COG1070	Carbohydrate kinase
SLIV_RS25410	COG3766	membrane
SLIV_RS25415	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SLIV_RS25420	COG2409	Drug exporters of the RND superfamily
SLIV_RS25435	COG1077	Cell shape determining protein MreB Mrl
SLIV_RS25440	COG0515	serine threonine protein kinase
SLIV_RS25440	COG2815	serine threonine protein kinase
SLIV_RS25460	COG1404	Belongs to the peptidase S8 family
SLIV_RS25465	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SLIV_RS25465	COG0825	malonyl-CoA metabolic process
SLIV_RS25470	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS25480	COG2186	Transcriptional regulator
SLIV_RS25490	COG1414	Transcriptional regulator
SLIV_RS25495	COG3386	PFAM SMP-30 Gluconolaconase
SLIV_RS25525	COG1175	transmembrane transport
SLIV_RS25530	COG0395	ABC-type sugar transport system, permease component
SLIV_RS25550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SLIV_RS25555	COG3507	Belongs to the glycosyl hydrolase 43 family
SLIV_RS25590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SLIV_RS25615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SLIV_RS25650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLIV_RS25660	COG4214	carbohydrate transport
SLIV_RS25665	COG1129	ABC transporter
SLIV_RS25705	COG2130	NADP-dependent
SLIV_RS25710	COG1764	response to oxidative stress
SLIV_RS25740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLIV_RS25745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS25750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLIV_RS25785	COG0789	Transcriptional regulator
SLIV_RS25790	COG0667	Aldo Keto reductase
SLIV_RS25805	COG1309	transcriptional regulator
SLIV_RS25810	COG0477	Major facilitator Superfamily
SLIV_RS25820	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLIV_RS25865	COG1358	cellular component organization or biogenesis
SLIV_RS25875	COG0586	Pfam SNARE associated Golgi protein
SLIV_RS25880	COG4585	Histidine kinase
SLIV_RS25885	COG2201	protein-glutamate methylesterase activity
SLIV_RS25990	COG4122	O-methyltransferase activity
SLIV_RS26095	COG3845	ABC transporter
SLIV_RS26120	COG1309	transcriptional regulator
SLIV_RS26125	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS26150	COG2247	cell wall binding repeat
SLIV_RS26150	COG0860	N-Acetylmuramoyl-L-alanine amidase
SLIV_RS26165	COG0477	Major facilitator Superfamily
SLIV_RS26175	COG2197	response regulator
SLIV_RS26180	COG4585	Histidine kinase
SLIV_RS26190	COG1131	(ABC) transporter
SLIV_RS26195	COG2030	dehydratase
SLIV_RS26210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SLIV_RS26225	COG0800	Aldolase
SLIV_RS26230	COG3022	response to hydroperoxide
SLIV_RS26280	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS26285	COG3540	Alkaline phosphatase
SLIV_RS26295	COG2814	Major facilitator Superfamily
SLIV_RS26300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLIV_RS26310	COG2197	response regulator
SLIV_RS26330	COG0672	)-iron permease
SLIV_RS26335	COG2837	iron assimilation
SLIV_RS26345	COG1120	ATPase activity
SLIV_RS26350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLIV_RS26375	COG0384	phenazine biosynthesis protein PhzF
SLIV_RS26380	COG5398	heme oxygenase
SLIV_RS26415	COG1994	Peptidase M50
SLIV_RS26435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SLIV_RS26445	COG2814	Major facilitator Superfamily
SLIV_RS26515	COG0174	glutamine synthetase
SLIV_RS26530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLIV_RS26530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SLIV_RS26540	COG4115	mRNA cleavage
SLIV_RS26545	COG2161	toxin-antitoxin pair type II binding
SLIV_RS26550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SLIV_RS26560	COG1609	Transcriptional regulator
SLIV_RS26565	COG1653	transport
SLIV_RS26570	COG1175	transmembrane transport
SLIV_RS26575	COG3833	ABC-type maltose transport systems, permease component
SLIV_RS26580	COG0366	Alpha amylase catalytic
SLIV_RS26605	COG1309	transcriptional regulator
SLIV_RS26640	COG2197	response regulator
SLIV_RS26655	COG0745	RESPONSE REGULATOR receiver
SLIV_RS26710	COG0501	Belongs to the peptidase M48B family
SLIV_RS26715	COG1733	regulation of RNA biosynthetic process
SLIV_RS26720	COG0702	epimerase
SLIV_RS26730	COG0174	glutamine synthetase
SLIV_RS26750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SLIV_RS26755	COG0321	lipoyl(octanoyl) transferase activity
SLIV_RS26770	COG1090	epimerase
SLIV_RS26800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLIV_RS26810	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLIV_RS26815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SLIV_RS26820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SLIV_RS26830	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SLIV_RS26840	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLIV_RS26860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLIV_RS26865	COG2226	methyltransferase
SLIV_RS26885	COG4585	Histidine kinase
SLIV_RS26890	COG2197	response regulator
SLIV_RS26895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SLIV_RS26900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SLIV_RS26920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLIV_RS26925	COG1104	cysteine desulfurase activity
SLIV_RS26930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SLIV_RS26935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SLIV_RS26945	COG1376	ErfK ybiS ycfS ynhG family protein
SLIV_RS26955	COG1845	cytochrome c oxidase, subunit III
SLIV_RS26960	COG2010	Cytochrome c
SLIV_RS26965	COG0723	plastoquinol--plastocyanin reductase activity
SLIV_RS26970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLIV_RS26975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SLIV_RS26980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLIV_RS26990	COG0745	RESPONSE REGULATOR receiver
SLIV_RS26995	COG2205	protein histidine kinase activity
SLIV_RS27045	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS27050	COG1022	Amp-dependent synthetase and ligase
SLIV_RS27065	COG0003	Pfam Anion-transporting ATPase
SLIV_RS27075	COG1940	carbohydrate kinase activity
SLIV_RS27100	COG4585	Histidine kinase
SLIV_RS27105	COG2197	response regulator
SLIV_RS27110	COG0205	6-phosphofructokinase activity
SLIV_RS27115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLIV_RS27130	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SLIV_RS27140	COG2193	ferroxidase activity
SLIV_RS27145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLIV_RS27150	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SLIV_RS27155	COG0515	serine threonine protein kinase
SLIV_RS27155	COG2815	serine threonine protein kinase
SLIV_RS27160	COG2022	thiamine diphosphate biosynthetic process
SLIV_RS27170	COG2022	thiamine diphosphate biosynthetic process
SLIV_RS27170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLIV_RS27175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLIV_RS27185	COG0352	thiamine-phosphate diphosphorylase activity
SLIV_RS27200	COG1233	COG1233 Phytoene dehydrogenase and related
SLIV_RS27205	COG1309	transcriptional regulator
SLIV_RS27235	COG0714	Associated with various cellular activities
SLIV_RS27245	COG0275	rRNA processing
SLIV_RS27255	COG0768	penicillin binding
SLIV_RS27260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SLIV_RS27270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLIV_RS27275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLIV_RS27285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SLIV_RS27290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SLIV_RS27295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SLIV_RS27300	COG1496	oxidoreductase activity
SLIV_RS27310	COG1799	cell septum assembly
SLIV_RS27320	COG3599	regulation of cell shape
SLIV_RS27325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SLIV_RS27335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SLIV_RS27350	COG0025	NhaP-type Na H and K H
SLIV_RS27385	COG0587	DNA-directed DNA polymerase activity
SLIV_RS27395	COG1432	Conserved Protein
SLIV_RS27415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SLIV_RS27435	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SLIV_RS27440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLIV_RS27445	COG0131	Imidazoleglycerol-phosphate dehydratase
SLIV_RS27455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SLIV_RS27460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SLIV_RS27465	COG0251	oxidation-reduction process
SLIV_RS27470	COG0107	imidazoleglycerol-phosphate synthase activity
SLIV_RS27490	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SLIV_RS27515	COG0134	indole-3-glycerol-phosphate synthase activity
SLIV_RS27525	COG0133	tryptophan synthase activity
SLIV_RS27530	COG0159	tryptophan synthase activity
SLIV_RS27540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SLIV_RS27545	COG2301	Belongs to the HpcH HpaI aldolase family
SLIV_RS27550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLIV_RS27580	COG0067	glutamate synthase
SLIV_RS27580	COG0070	glutamate synthase
SLIV_RS27580	COG0069	glutamate synthase activity
SLIV_RS27600	COG2304	oxidoreductase activity
SLIV_RS27605	COG2968	Membrane
SLIV_RS27615	COG1605	Chorismate mutase
SLIV_RS27615	COG0287	Prephenate dehydrogenase
SLIV_RS27635	COG0737	Belongs to the 5'-nucleotidase family
SLIV_RS27660	COG0411	ABC transporter
SLIV_RS27690	COG2050	protein possibly involved in aromatic compounds catabolism
SLIV_RS27715	COG1643	Atp-dependent helicase
SLIV_RS27720	COG2226	methyltransferase
SLIV_RS27735	COG0237	dephospho-CoA kinase activity
SLIV_RS27750	COG2226	methyltransferase
SLIV_RS27770	COG2267	carboxylic ester hydrolase activity
SLIV_RS27795	COG0402	S-adenosylhomocysteine deaminase activity
SLIV_RS27845	COG0598	Magnesium transport protein CorA
SLIV_RS27850	COG2226	methyltransferase
SLIV_RS27855	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SLIV_RS27855	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SLIV_RS27860	COG2313	pseudouridylate synthase activity
SLIV_RS27870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLIV_RS27875	COG0584	glycerophosphoryl diester phosphodiesterase
SLIV_RS27885	COG0556	nucleotide-excision repair
SLIV_RS27905	COG0387	Pfam Sodium calcium exchanger
SLIV_RS27910	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SLIV_RS27925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLIV_RS27950	COG0322	excinuclease ABC activity
SLIV_RS27955	COG1660	Displays ATPase and GTPase activities
SLIV_RS27960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLIV_RS27965	COG1481	regulation of sporulation
SLIV_RS27975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SLIV_RS27980	COG0126	phosphoglycerate kinase activity
SLIV_RS27985	COG0149	triose-phosphate isomerase activity
SLIV_RS27990	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SLIV_RS28000	COG0166	Belongs to the GPI family
SLIV_RS28015	COG0363	glucosamine-6-phosphate deaminase activity
SLIV_RS28030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLIV_RS28040	COG0109	protoheme IX farnesyltransferase activity
SLIV_RS28070	COG1131	(ABC) transporter
SLIV_RS28075	COG2746	aminoglycoside 3-N-acetyltransferase activity
SLIV_RS28090	COG0719	Fe-S assembly protein
SLIV_RS28100	COG0396	ATPase activity
SLIV_RS28105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLIV_RS28110	COG0822	iron-sulfur transferase activity
SLIV_RS28115	COG2151	metal-sulfur cluster biosynthetic enzyme
SLIV_RS28120	COG2076	Multidrug Resistance protein
SLIV_RS28125	COG3226	Transcriptional regulator
SLIV_RS28130	COG2171	N-acyltransferase activity
SLIV_RS28150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLIV_RS28195	COG1309	transcriptional regulator
SLIV_RS28210	COG1063	alcohol dehydrogenase
SLIV_RS28230	COG1349	DNA-binding transcription factor activity
SLIV_RS28235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLIV_RS28240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLIV_RS28265	COG1802	Transcriptional regulator
SLIV_RS28280	COG1175	transmembrane transport
SLIV_RS28285	COG0395	ABC-type sugar transport system, permease component
SLIV_RS28300	COG3507	Belongs to the glycosyl hydrolase 43 family
SLIV_RS28310	COG2755	lipolytic protein G-D-S-L family
SLIV_RS28315	COG3866	Pectate lyase
SLIV_RS28320	COG4677	pectinesterase activity
SLIV_RS28335	COG1595	DNA-templated transcription, initiation
SLIV_RS28340	COG0768	penicillin binding
SLIV_RS28350	COG1414	Transcriptional regulator
SLIV_RS28375	COG5285	phytanoyl-CoA dioxygenase
SLIV_RS28380	COG1917	Cupin 2, conserved barrel domain protein
SLIV_RS28385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLIV_RS28390	COG0456	acetyltransferase
SLIV_RS28395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SLIV_RS28450	COG1797	cobyrinic acid a,c-diamide synthase activity
SLIV_RS28470	COG1492	cobalamin metabolic process
SLIV_RS28475	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SLIV_RS28490	COG0235	Class ii aldolase
SLIV_RS28510	COG0488	(ABC) transporter
SLIV_RS28560	COG3387	PFAM Glycoside hydrolase 15-related
SLIV_RS28575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLIV_RS28590	COG1404	Belongs to the peptidase S8 family
SLIV_RS28600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLIV_RS28605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SLIV_RS28625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SLIV_RS28640	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS28650	COG2186	Transcriptional regulator
SLIV_RS28675	COG0560	Phosphoserine phosphatase
SLIV_RS28675	COG3830	Belongs to the UPF0237 family
SLIV_RS28685	COG1716	ATPase activity
SLIV_RS28685	COG0842	Transport permease protein
SLIV_RS28685	COG1131	(ABC) transporter
SLIV_RS28695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SLIV_RS28700	COG4221	oxidoreductase activity
SLIV_RS28705	COG4585	Histidine kinase
SLIV_RS28710	COG2197	response regulator
SLIV_RS28725	COG1119	ATPase activity
SLIV_RS28745	COG1881	PFAM PEBP family protein
SLIV_RS28755	COG2094	Belongs to the DNA glycosylase MPG family
SLIV_RS28790	COG0647	UMP catabolic process
SLIV_RS28795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLIV_RS28800	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLIV_RS28805	COG1120	ATPase activity
SLIV_RS28825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SLIV_RS28830	COG0497	DNA recombination
SLIV_RS28835	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS28845	COG3387	PFAM Glycoside hydrolase 15-related
SLIV_RS28850	COG0504	CTP synthase activity
SLIV_RS28855	COG0494	nUDIX hydrolase
SLIV_RS28865	COG0686	Belongs to the AlaDH PNT family
SLIV_RS28880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SLIV_RS28885	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SLIV_RS28890	COG1187	pseudouridine synthase activity
SLIV_RS28895	COG0494	nUDIX hydrolase
SLIV_RS28905	COG3541	Predicted nucleotidyltransferase
SLIV_RS28930	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SLIV_RS28940	COG1160	GTP binding
SLIV_RS28965	COG0671	phosphoesterase, PA-phosphatase related
SLIV_RS28975	COG0477	Major facilitator Superfamily
SLIV_RS28980	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS28985	COG1799	cell septum assembly
SLIV_RS29005	COG2197	response regulator
SLIV_RS29010	COG4585	Histidine kinase
SLIV_RS29035	COG0587	DNA-directed DNA polymerase activity
SLIV_RS29045	COG0662	Cupin 2, conserved barrel domain protein
SLIV_RS29045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SLIV_RS29090	COG1725	Transcriptional regulator
SLIV_RS29105	COG2755	lipolytic protein G-D-S-L family
SLIV_RS29115	COG1595	DNA-templated transcription, initiation
SLIV_RS29150	COG2188	Transcriptional regulator
SLIV_RS29155	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SLIV_RS29165	COG1309	transcriptional regulator
SLIV_RS29170	COG0243	molybdopterin cofactor binding
SLIV_RS29175	COG2851	Citrate transporter
SLIV_RS29190	COG3842	ATPase activity
SLIV_RS29210	COG0640	Transcriptional regulator
SLIV_RS29220	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS29240	COG0789	Transcriptional regulator
SLIV_RS29260	COG3876	Protein conserved in bacteria
SLIV_RS29290	COG2149	membrane
SLIV_RS29295	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLIV_RS29315	COG1063	alcohol dehydrogenase
SLIV_RS29320	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS29330	COG3265	gluconokinase activity
SLIV_RS29340	COG3012	SEC-C Motif Domain Protein
SLIV_RS29380	COG0667	Aldo Keto reductase
SLIV_RS29385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLIV_RS29395	COG0598	Magnesium transport protein CorA
SLIV_RS29400	COG0588	phosphoglycerate mutase activity
SLIV_RS29415	COG0215	cysteine-tRNA ligase activity
SLIV_RS29425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SLIV_RS29430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLIV_RS29435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLIV_RS29440	COG1414	Transcriptional regulator
SLIV_RS29445	COG1410	methionine synthase
SLIV_RS29445	COG0646	methionine synthase
SLIV_RS29450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLIV_RS29455	COG4166	transmembrane transport
SLIV_RS29460	COG2197	response regulator
SLIV_RS29470	COG0517	IMP dehydrogenase activity
SLIV_RS29470	COG1994	Peptidase M50
SLIV_RS29490	COG1222	aaa ATPase
SLIV_RS29495	COG4122	O-methyltransferase activity
SLIV_RS29510	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLIV_RS29515	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLIV_RS29520	COG1609	Transcriptional regulator
SLIV_RS29530	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLIV_RS29535	COG0545	Peptidyl-prolyl cis-trans isomerase
SLIV_RS29565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLIV_RS29570	COG0805	protein transport
SLIV_RS29605	COG0564	pseudouridine synthase activity
SLIV_RS29620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLIV_RS29625	COG0517	IMP dehydrogenase activity
SLIV_RS29625	COG4175	Glycine betaine
SLIV_RS29630	COG4176	ABC-type proline glycine betaine transport system permease component
SLIV_RS29655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SLIV_RS29660	COG2186	Transcriptional regulator
SLIV_RS29665	COG0174	glutamine synthetase
SLIV_RS29670	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS29720	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SLIV_RS29725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SLIV_RS29730	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SLIV_RS29735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SLIV_RS29740	COG5002	protein histidine kinase activity
SLIV_RS29745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SLIV_RS29750	COG0072	phenylalanine-tRNA ligase activity
SLIV_RS29750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLIV_RS29770	COG1649	PFAM Uncharacterised BCR, COG1649
SLIV_RS29780	COG0697	spore germination
SLIV_RS29820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SLIV_RS29825	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SLIV_RS29830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SLIV_RS29835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLIV_RS29840	COG1438	arginine binding
SLIV_RS29870	COG0165	Argininosuccinate lyase
SLIV_RS29885	COG0477	Major facilitator Superfamily
SLIV_RS29890	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS29890	COG0204	Acyl-transferase
SLIV_RS29895	COG0584	glycerophosphoryl diester phosphodiesterase
SLIV_RS29920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLIV_RS29925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLIV_RS29930	COG2011	ABC-type metal ion transport system permease component
SLIV_RS29935	COG1464	Belongs to the NlpA lipoprotein family
SLIV_RS29950	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLIV_RS29955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SLIV_RS29955	COG1648	precorrin-2 dehydrogenase activity
SLIV_RS30010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SLIV_RS30020	COG0456	acetyltransferase
SLIV_RS30065	COG1175	transmembrane transport
SLIV_RS30070	COG0395	ABC-type sugar transport system, permease component
SLIV_RS30095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SLIV_RS30110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLIV_RS30130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SLIV_RS30135	COG1560	Kdo2-lipid A biosynthetic process
SLIV_RS30140	COG0438	transferase activity, transferring glycosyl groups
SLIV_RS30150	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SLIV_RS30155	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SLIV_RS30160	COG0217	transcriptional regulatory protein
SLIV_RS30165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SLIV_RS30170	COG0632	four-way junction helicase activity
SLIV_RS30175	COG2255	four-way junction helicase activity
SLIV_RS30185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLIV_RS30190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLIV_RS30195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SLIV_RS30200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLIV_RS30205	COG1196	nuclear chromosome segregation
SLIV_RS30210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SLIV_RS30220	COG0124	histidyl-tRNA synthetase
SLIV_RS30235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SLIV_RS30255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SLIV_RS30260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SLIV_RS30270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SLIV_RS30280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SLIV_RS30285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SLIV_RS30290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SLIV_RS30300	COG0006	proline dipeptidase activity
SLIV_RS30305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SLIV_RS30310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SLIV_RS30320	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SLIV_RS30325	COG0540	Belongs to the ATCase OTCase family
SLIV_RS30330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLIV_RS30340	COG0505	Belongs to the CarA family
SLIV_RS30345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SLIV_RS30350	COG0167	dihydroorotate dehydrogenase activity
SLIV_RS30355	COG0284	orotidine-5'-phosphate decarboxylase activity
SLIV_RS30365	COG0194	GDP metabolic process
SLIV_RS30370	COG1758	RNA polymerase activity
SLIV_RS30380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLIV_RS30395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SLIV_RS30415	COG0515	serine threonine protein kinase
SLIV_RS30430	COG1653	transport
SLIV_RS30435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SLIV_RS30440	COG2390	Transcriptional regulator
SLIV_RS30460	COG0531	amino acid
SLIV_RS30480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLIV_RS30505	COG2233	PERMEase
SLIV_RS30515	COG2223	nitrite transmembrane transporter activity
SLIV_RS30545	COG3201	nicotinamide mononucleotide transporter
SLIV_RS30550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLIV_RS30550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLIV_RS30555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SLIV_RS30560	COG0140	phosphoribosyl-ATP diphosphatase activity
SLIV_RS30565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SLIV_RS30610	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS30635	COG0463	Glycosyl transferase, family 2
SLIV_RS30650	COG2270	Major facilitator Superfamily
SLIV_RS30660	COG2364	Membrane
SLIV_RS30690	COG4336	lyase activity
SLIV_RS30695	COG2814	Major facilitator Superfamily
SLIV_RS30725	COG0326	Molecular chaperone. Has ATPase activity
SLIV_RS30745	COG2018	Roadblock/LC7 domain
SLIV_RS30760	COG3706	GGDEF domain
SLIV_RS30765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SLIV_RS30780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLIV_RS30790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLIV_RS30820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLIV_RS30840	COG1716	ATPase activity
SLIV_RS30860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SLIV_RS30870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLIV_RS30870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLIV_RS30880	COG1609	Transcriptional regulator
SLIV_RS30905	COG0384	phenazine biosynthesis protein PhzF
SLIV_RS30910	COG2197	response regulator
SLIV_RS30915	COG4585	Histidine kinase
SLIV_RS30925	COG1136	(ABC) transporter
SLIV_RS30965	COG0697	spore germination
SLIV_RS30980	COG0723	plastoquinol--plastocyanin reductase activity
SLIV_RS31000	COG0006	proline dipeptidase activity
SLIV_RS31045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLIV_RS31060	COG2318	DinB family
SLIV_RS31070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLIV_RS31080	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SLIV_RS31085	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS31115	COG2801	Transposase and inactivated derivatives
SLIV_RS31120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLIV_RS31135	COG2770	Histidine kinase
SLIV_RS31135	COG2208	phosphoserine phosphatase activity
SLIV_RS31140	COG1968	undecaprenyl-diphosphatase activity
SLIV_RS31150	COG0183	Belongs to the thiolase family
SLIV_RS31165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLIV_RS31200	COG0110	maltose O-acetyltransferase activity
SLIV_RS31225	COG0640	Transcriptional regulator
SLIV_RS31240	COG0714	Associated with various cellular activities
SLIV_RS31245	COG3864	Putative metallopeptidase domain
SLIV_RS31250	COG1832	CoA-binding protein
SLIV_RS31260	COG1739	Uncharacterized protein family UPF0029
SLIV_RS31265	COG0420	3'-5' exonuclease activity
SLIV_RS31270	COG0419	ATPase involved in DNA repair
SLIV_RS31275	COG1522	sequence-specific DNA binding
SLIV_RS31300	COG0626	cystathionine gamma-synthase activity
SLIV_RS31325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLIV_RS31365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLIV_RS31365	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SLIV_RS31375	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLIV_RS31380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SLIV_RS31405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS31405	COG3320	Male sterility
SLIV_RS31410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS31415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLIV_RS31420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SLIV_RS31425	COG0022	dehydrogenase e1 component
SLIV_RS31430	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLIV_RS31435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS31440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLIV_RS31450	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLIV_RS31450	COG0596	Alpha beta hydrolase
SLIV_RS31455	COG1595	DNA-templated transcription, initiation
SLIV_RS31460	COG2188	Transcriptional regulator
SLIV_RS31465	COG1940	carbohydrate kinase activity
SLIV_RS31470	COG2197	response regulator
SLIV_RS31475	COG4585	Histidine kinase
SLIV_RS31500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLIV_RS31520	COG0456	acetyltransferase
SLIV_RS31535	COG2226	methyltransferase
SLIV_RS31540	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SLIV_RS31545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLIV_RS31550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SLIV_RS31555	COG0156	8-amino-7-oxononanoate synthase activity
SLIV_RS31585	COG0740	serine-type endopeptidase activity
SLIV_RS31590	COG2161	toxin-antitoxin pair type II binding
SLIV_RS31595	COG0831	urea catabolic process
SLIV_RS31600	COG0832	Belongs to the urease beta subunit family
SLIV_RS31605	COG0804	urea catabolic process
SLIV_RS31615	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SLIV_RS31620	COG0829	nickel cation binding
SLIV_RS31635	COG0204	Acyl-transferase
SLIV_RS31650	COG0477	Major facilitator Superfamily
SLIV_RS31660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLIV_RS31665	COG1834	amidinotransferase
SLIV_RS31670	COG1522	sequence-specific DNA binding
SLIV_RS31675	COG3279	Response regulator of the LytR AlgR family
SLIV_RS31685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLIV_RS31690	COG3275	phosphorelay sensor kinase activity
SLIV_RS31705	COG0205	6-phosphofructokinase activity
SLIV_RS31710	COG3442	glutamine amidotransferase
SLIV_RS31715	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLIV_RS31720	COG0242	peptide deformylase activity
SLIV_RS31730	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS31740	COG2124	cytochrome p450
SLIV_RS31745	COG3424	synthase
SLIV_RS31755	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS31765	COG1793	dna ligase
SLIV_RS31775	COG3800	Transcriptional regulator
SLIV_RS31775	COG1396	sequence-specific DNA binding
SLIV_RS31785	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS31790	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS31805	COG0477	Major facilitator Superfamily
SLIV_RS31825	COG0477	Major facilitator Superfamily
SLIV_RS31860	COG0714	Associated with various cellular activities
SLIV_RS31875	COG0592	DNA-directed DNA polymerase activity
SLIV_RS31895	COG0129	dihydroxy-acid dehydratase activity
SLIV_RS31910	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS31925	COG1940	carbohydrate kinase activity
SLIV_RS31930	COG1070	Carbohydrate kinase
SLIV_RS31935	COG2115	Belongs to the xylose isomerase family
SLIV_RS31945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLIV_RS32005	COG2018	Roadblock/LC7 domain
SLIV_RS32015	COG1946	Acyl-CoA thioesterase
SLIV_RS32030	COG0254	rRNA binding
SLIV_RS32040	COG1132	(ABC) transporter
SLIV_RS32045	COG1132	(ABC) transporter
SLIV_RS32060	COG1132	(ABC) transporter
SLIV_RS32070	COG2072	flavoprotein involved in K transport
SLIV_RS32075	COG0432	Pfam Uncharacterised protein family UPF0047
SLIV_RS32095	COG3290	protein histidine kinase activity
SLIV_RS32100	COG4565	transcriptional regulatory protein
SLIV_RS32110	COG2080	2 iron, 2 sulfur cluster binding
SLIV_RS32115	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SLIV_RS32120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLIV_RS32130	COG3387	PFAM Glycoside hydrolase 15-related
SLIV_RS32145	COG4221	oxidoreductase activity
SLIV_RS32180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLIV_RS32210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLIV_RS32220	COG1960	acyl-CoA dehydrogenase activity
SLIV_RS32235	COG1902	pentaerythritol trinitrate reductase activity
SLIV_RS32240	COG0640	Transcriptional regulator
SLIV_RS32260	COG1309	transcriptional regulator
SLIV_RS32270	COG0671	phosphoesterase, PA-phosphatase related
SLIV_RS32305	COG1309	transcriptional regulator
SLIV_RS32325	COG0584	glycerophosphoryl diester phosphodiesterase
SLIV_RS32350	COG0204	Acyl-transferase
SLIV_RS32370	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SLIV_RS32400	COG1660	Displays ATPase and GTPase activities
SLIV_RS32410	COG0445	tRNA wobble uridine modification
SLIV_RS32415	COG4585	Histidine kinase
SLIV_RS32420	COG2197	response regulator
SLIV_RS32440	COG0738	Major facilitator superfamily
SLIV_RS32445	COG1609	Transcriptional regulator
SLIV_RS32455	COG1175	transmembrane transport
SLIV_RS32460	COG0395	ABC-type sugar transport system, permease component
SLIV_RS32465	COG3250	beta-galactosidase activity
SLIV_RS32480	COG2723	6-phospho-beta-galactosidase activity
SLIV_RS32485	COG0395	ABC-type sugar transport system, permease component
SLIV_RS32490	COG1175	transmembrane transport
SLIV_RS32495	COG1653	transport
SLIV_RS32500	COG1501	Belongs to the glycosyl hydrolase 31 family
SLIV_RS32525	COG0783	Belongs to the Dps family
SLIV_RS32530	COG0673	inositol 2-dehydrogenase activity
SLIV_RS32550	COG2608	mercury ion transmembrane transporter activity
SLIV_RS32565	COG2813	Specifically methylates the guanine in position
SLIV_RS32575	COG1940	carbohydrate kinase activity
SLIV_RS32610	COG1136	(ABC) transporter
SLIV_RS32615	COG0577	efflux transmembrane transporter activity
SLIV_RS32630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLIV_RS32640	COG1349	DNA-binding transcription factor activity
SLIV_RS32675	COG0463	Glycosyl transferase, family 2
SLIV_RS32680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SLIV_RS32705	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS32785	COG2801	Transposase and inactivated derivatives
SLIV_RS32800	COG0531	amino acid
SLIV_RS32840	COG0667	Aldo Keto reductase
SLIV_RS32865	COG2267	carboxylic ester hydrolase activity
SLIV_RS32870	COG0673	inositol 2-dehydrogenase activity
SLIV_RS32890	COG1012	belongs to the aldehyde dehydrogenase family
SLIV_RS32900	COG1733	regulation of RNA biosynthetic process
SLIV_RS32910	COG0604	alcohol dehydrogenase
SLIV_RS32910	COG3321	synthase
SLIV_RS32925	COG4585	Histidine kinase
SLIV_RS32930	COG2197	response regulator
SLIV_RS32945	COG4566	intracellular signal transduction
SLIV_RS32970	COG2801	Transposase and inactivated derivatives
SLIV_RS33010	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SLIV_RS33025	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SLIV_RS33040	COG0583	DNA-binding transcription factor activity
SLIV_RS33045	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS33085	COG0297	glycogen (starch) synthase activity
SLIV_RS33090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SLIV_RS33100	COG3537	Alpha-1,2-mannosidase
SLIV_RS33130	COG1609	Transcriptional regulator
SLIV_RS33135	COG1653	transport
SLIV_RS33140	COG1175	transmembrane transport
SLIV_RS33145	COG0395	ABC-type sugar transport system, permease component
SLIV_RS33170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLIV_RS33205	COG0531	amino acid
SLIV_RS33215	COG0726	polysaccharide deacetylase
SLIV_RS33260	COG0583	DNA-binding transcription factor activity
SLIV_RS33270	COG0583	DNA-binding transcription factor activity
SLIV_RS33280	COG1053	succinate dehydrogenase
SLIV_RS33285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SLIV_RS33310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLIV_RS33320	COG3360	Dodecin
SLIV_RS33325	COG2182	Extracellular solute-binding protein
SLIV_RS33330	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SLIV_RS33335	COG0121	glutamine amidotransferase
SLIV_RS33340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLIV_RS33345	COG3572	ergothioneine biosynthetic process
SLIV_RS33390	COG0596	Alpha beta hydrolase
SLIV_RS33395	COG3629	intracellular signal transduction
SLIV_RS33395	COG3903	Transcriptional regulator
SLIV_RS33415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLIV_RS33420	COG3976	FMN-binding domain protein
SLIV_RS33420	COG1053	succinate dehydrogenase
SLIV_RS33440	COG4221	oxidoreductase activity
SLIV_RS33450	COG0583	DNA-binding transcription factor activity
SLIV_RS33465	COG1609	Transcriptional regulator
SLIV_RS33470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLIV_RS33475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SLIV_RS33480	COG0242	peptide deformylase activity
SLIV_RS33500	COG1131	(ABC) transporter
SLIV_RS33540	COG4251	negative regulation of phosphorylation
SLIV_RS33545	COG0784	Response regulator, receiver
SLIV_RS33610	COG1309	transcriptional regulator
SLIV_RS33635	COG0800	Aldolase
SLIV_RS33690	COG0702	epimerase
SLIV_RS33695	COG1846	Transcriptional regulator
SLIV_RS33700	COG2409	Drug exporters of the RND superfamily
SLIV_RS33715	COG0668	transmembrane transport
SLIV_RS33755	COG3540	Alkaline phosphatase
SLIV_RS33775	COG1131	(ABC) transporter
SLIV_RS33780	COG1725	Transcriptional regulator
SLIV_RS33805	COG0577	efflux transmembrane transporter activity
SLIV_RS33805	COG1136	(ABC) transporter
SLIV_RS33810	COG1556	Lactate utilization protein
SLIV_RS33815	COG1139	Iron-sulfur cluster binding protein
SLIV_RS33820	COG0247	lactate metabolic process
SLIV_RS33825	COG1070	Carbohydrate kinase
SLIV_RS33830	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS33830	COG3347	Dehydrogenase
SLIV_RS33835	COG4952	isomerase
SLIV_RS33840	COG1129	ABC transporter
SLIV_RS33845	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLIV_RS33855	COG1879	ABC-type sugar transport system periplasmic component
SLIV_RS33865	COG1609	Transcriptional regulator
SLIV_RS33880	COG1595	DNA-templated transcription, initiation
SLIV_RS33885	COG1357	PFAM Pentapeptide repeats (8 copies)
SLIV_RS33895	COG1309	transcriptional regulator
SLIV_RS33905	COG2706	6-phosphogluconolactonase activity
SLIV_RS33950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SLIV_RS33950	COG1796	DNA polymerase
SLIV_RS33985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLIV_RS33990	COG1366	Belongs to the anti-sigma-factor antagonist family
SLIV_RS34010	COG0435	Glutathione S-transferase
SLIV_RS34025	COG2124	cytochrome p450
SLIV_RS34050	COG0667	Aldo Keto reductase
SLIV_RS34065	COG3250	beta-galactosidase activity
SLIV_RS34095	COG2890	protein-(glutamine-N5) methyltransferase activity
SLIV_RS34110	COG0248	Ppx GppA phosphatase
SLIV_RS34115	COG5265	(ABC) transporter
SLIV_RS34185	COG1132	(ABC) transporter
SLIV_RS34200	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS34220	COG0673	inositol 2-dehydrogenase activity
SLIV_RS34225	COG1846	Transcriptional regulator
SLIV_RS34225	COG1940	carbohydrate kinase activity
SLIV_RS34255	COG1309	transcriptional regulator
SLIV_RS34325	COG0673	inositol 2-dehydrogenase activity
SLIV_RS34340	COG2508	Transcriptional regulator
SLIV_RS34345	COG0410	ABC transporter
SLIV_RS34395	COG1132	(ABC) transporter
SLIV_RS34440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLIV_RS34445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SLIV_RS34450	COG2080	2 iron, 2 sulfur cluster binding
SLIV_RS34460	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS34465	COG1295	ribonuclease BN
SLIV_RS34495	COG0477	Major facilitator Superfamily
SLIV_RS34510	COG3290	protein histidine kinase activity
SLIV_RS34550	COG0277	FAD linked oxidase domain protein
SLIV_RS34575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLIV_RS34580	COG0395	ABC-type sugar transport system, permease component
SLIV_RS34585	COG1175	transmembrane transport
SLIV_RS34595	COG1609	Transcriptional regulator
SLIV_RS34655	COG4221	oxidoreductase activity
SLIV_RS34675	COG3397	chitin binding
SLIV_RS34710	COG0488	(ABC) transporter
SLIV_RS34730	COG1595	DNA-templated transcription, initiation
SLIV_RS34750	COG1233	COG1233 Phytoene dehydrogenase and related
SLIV_RS34785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SLIV_RS34790	COG1937	Protein conserved in bacteria
SLIV_RS34805	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SLIV_RS34825	COG2235	arginine
SLIV_RS34875	COG0505	Belongs to the CarA family
SLIV_RS34885	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SLIV_RS34890	COG1191	sigma factor activity
SLIV_RS34910	COG0783	Belongs to the Dps family
SLIV_RS34915	COG0655	NAD(P)H dehydrogenase (quinone) activity
SLIV_RS34945	COG0583	DNA-binding transcription factor activity
SLIV_RS34955	COG2018	Roadblock/LC7 domain
SLIV_RS34970	COG2124	cytochrome p450
SLIV_RS34975	COG2124	cytochrome p450
SLIV_RS34980	COG2186	Transcriptional regulator
SLIV_RS34990	COG2376	Dihydroxyacetone kinase
SLIV_RS34995	COG0698	ribose 5-phosphate isomerase
SLIV_RS35000	COG0149	triose-phosphate isomerase activity
SLIV_RS35005	COG1082	Xylose isomerase domain protein TIM barrel
SLIV_RS35010	COG2084	Dehydrogenase
SLIV_RS35015	COG3340	Belongs to the peptidase S51 family
SLIV_RS35030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SLIV_RS35035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLIV_RS35040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLIV_RS35045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SLIV_RS35055	COG0142	geranyltranstransferase activity
SLIV_RS35065	COG0142	geranyltranstransferase activity
SLIV_RS35090	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SLIV_RS35105	COG0789	Transcriptional regulator
SLIV_RS35135	COG0745	RESPONSE REGULATOR receiver
SLIV_RS35140	COG2205	protein histidine kinase activity
SLIV_RS35145	COG2340	Cysteine-rich secretory protein family
SLIV_RS35150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLIV_RS35155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLIV_RS35160	COG3321	synthase
SLIV_RS35160	COG0604	alcohol dehydrogenase
SLIV_RS35180	COG0739	heme binding
SLIV_RS35190	COG1486	melibiose metabolic process
SLIV_RS35195	COG0395	ABC-type sugar transport system, permease component
SLIV_RS35220	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SLIV_RS35230	COG0395	ABC-type sugar transport system, permease component
SLIV_RS35235	COG1175	transmembrane transport
SLIV_RS35240	COG2182	Extracellular solute-binding protein
SLIV_RS35245	COG2188	Transcriptional regulator
SLIV_RS35250	COG0673	inositol 2-dehydrogenase activity
SLIV_RS35260	COG1278	Cold shock
SLIV_RS35275	COG3386	PFAM SMP-30 Gluconolaconase
SLIV_RS35280	COG1522	sequence-specific DNA binding
SLIV_RS35285	COG4221	oxidoreductase activity
SLIV_RS35300	COG4221	oxidoreductase activity
SLIV_RS35315	COG0666	response to abiotic stimulus
SLIV_RS35335	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS35345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLIV_RS35360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SLIV_RS35370	COG0513	Belongs to the DEAD box helicase family
SLIV_RS35400	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLIV_RS35405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLIV_RS35410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLIV_RS35415	COG1120	ATPase activity
SLIV_RS35425	COG1132	(ABC) transporter
SLIV_RS35435	COG1132	(ABC) transporter
SLIV_RS35440	COG2382	esterase
SLIV_RS35450	COG3408	Glycogen debranching enzyme
SLIV_RS35495	COG0483	inositol monophosphate 1-phosphatase activity
SLIV_RS35505	COG0346	lactoylglutathione lyase activity
SLIV_RS35510	COG1120	ATPase activity
SLIV_RS35515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLIV_RS35545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLIV_RS35555	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SLIV_RS35585	COG0596	Alpha beta hydrolase
SLIV_RS35610	COG1609	Transcriptional regulator
SLIV_RS35615	COG0395	ABC-type sugar transport system, permease component
SLIV_RS35620	COG1175	transmembrane transport
SLIV_RS35630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SLIV_RS35650	COG0477	Major facilitator Superfamily
SLIV_RS35675	COG1984	allophanate hydrolase subunit 2
SLIV_RS35685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SLIV_RS35700	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SLIV_RS35715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SLIV_RS35720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SLIV_RS35720	COG1263	PTS System
SLIV_RS35730	COG1404	Belongs to the peptidase S8 family
SLIV_RS35745	COG0667	Aldo Keto reductase
SLIV_RS35775	COG2409	Drug exporters of the RND superfamily
SLIV_RS35780	COG4585	Histidine kinase
SLIV_RS35785	COG2197	response regulator
SLIV_RS35820	COG1595	DNA-templated transcription, initiation
SLIV_RS35840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SLIV_RS35845	COG0739	heme binding
SLIV_RS35885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SLIV_RS35900	COG1215	transferase activity, transferring glycosyl groups
SLIV_RS35910	COG4310	Domain of unknown function (DUF2172)
SLIV_RS35925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLIV_RS35960	COG0367	asparagine synthase
SLIV_RS35980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLIV_RS35995	COG0753	catalase activity
SLIV_RS36015	COG0477	Major facilitator Superfamily
SLIV_RS36020	COG1132	(ABC) transporter
SLIV_RS36045	COG3408	Glycogen debranching enzyme
SLIV_RS36075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLIV_RS36085	COG1609	Transcriptional regulator
SLIV_RS36095	COG4948	Mandelate Racemase Muconate Lactonizing
SLIV_RS36105	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS36125	COG1653	transport
SLIV_RS36135	COG3618	amidohydrolase
SLIV_RS36145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLIV_RS36155	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLIV_RS36160	COG1414	Transcriptional regulator
SLIV_RS36165	COG1802	Transcriptional regulator
SLIV_RS36190	COG0129	dihydroxy-acid dehydratase activity
SLIV_RS36195	COG0589	response to stress
SLIV_RS36200	COG3387	PFAM Glycoside hydrolase 15-related
SLIV_RS36205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SLIV_RS36240	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS36265	COG0488	(ABC) transporter
SLIV_RS36290	COG2508	Transcriptional regulator
SLIV_RS36290	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SLIV_RS36295	COG0019	diaminopimelate decarboxylase activity
SLIV_RS36300	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SLIV_RS36315	COG0318	PFAM AMP-dependent synthetase and ligase
SLIV_RS36320	COG1309	transcriptional regulator
SLIV_RS36340	COG1073	alpha beta
SLIV_RS36345	COG2319	Wd-40 repeat
SLIV_RS36370	COG2072	flavoprotein involved in K transport
SLIV_RS36375	COG0667	Aldo Keto reductase
SLIV_RS36380	COG0583	DNA-binding transcription factor activity
SLIV_RS36400	COG0110	maltose O-acetyltransferase activity
SLIV_RS36405	COG1472	Belongs to the glycosyl hydrolase 3 family
SLIV_RS36415	COG1175	transmembrane transport
SLIV_RS36425	COG1609	Transcriptional regulator
SLIV_RS36445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SLIV_RS36445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SLIV_RS36450	COG3345	alpha-galactosidase
SLIV_RS36470	COG0494	nUDIX hydrolase
SLIV_RS36480	COG0494	nUDIX hydrolase
SLIV_RS36495	COG1940	carbohydrate kinase activity
SLIV_RS36500	COG3345	alpha-galactosidase
SLIV_RS36510	COG0395	ABC-type sugar transport system, permease component
SLIV_RS36565	COG0110	maltose O-acetyltransferase activity
SLIV_RS36575	COG1063	alcohol dehydrogenase
SLIV_RS36610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLIV_RS36625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLIV_RS36690	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SLIV_RS36705	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS36725	COG1309	transcriptional regulator
SLIV_RS36755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLIV_RS36780	COG1140	nitrate reductase beta subunit
SLIV_RS36820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLIV_RS36820	COG0574	Belongs to the PEP-utilizing enzyme family
SLIV_RS36910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLIV_RS36915	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SLIV_RS36935	COG0142	geranyltranstransferase activity
SLIV_RS36940	COG3046	protein related to deoxyribodipyrimidine photolyase
SLIV_RS36950	COG0702	epimerase
SLIV_RS36970	COG2205	protein histidine kinase activity
SLIV_RS36975	COG0745	RESPONSE REGULATOR receiver
SLIV_RS37005	COG0589	response to stress
SLIV_RS37010	COG1063	alcohol dehydrogenase
SLIV_RS37040	COG0589	response to stress
SLIV_RS37070	COG2326	polyphosphate kinase activity
SLIV_RS37105	COG1595	DNA-templated transcription, initiation
SLIV_RS37135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLIV_RS37145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLIV_RS37150	COG3655	Transcriptional regulator
SLIV_RS37170	COG1309	transcriptional regulator
SLIV_RS37235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLIV_RS37245	COG3321	synthase
SLIV_RS37245	COG0604	alcohol dehydrogenase
SLIV_RS37250	COG2070	2-Nitropropane dioxygenase
SLIV_RS37250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SLIV_RS37265	COG2072	flavoprotein involved in K transport
SLIV_RS37270	COG1131	(ABC) transporter
SLIV_RS37285	COG3507	Belongs to the glycosyl hydrolase 43 family
SLIV_RS37315	COG1028	Short-chain dehydrogenase reductase Sdr
SLIV_RS37335	COG3293	Transposase
SLIV_RS37340	COG0726	polysaccharide deacetylase
SLIV_RS37380	COG0583	DNA-binding transcription factor activity
SLIV_RS37390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SLIV_RS37415	COG2801	Transposase and inactivated derivatives
SLIV_RS37425	COG2814	Major facilitator Superfamily
SLIV_RS37440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLIV_RS37455	COG3293	Transposase
SLIV_RS37495	COG1349	DNA-binding transcription factor activity
SLIV_RS37510	COG2801	Transposase and inactivated derivatives
SLIV_RS37635	COG3629	intracellular signal transduction