locus-tag	class	description
EKH77_RS00065	COG0028	Belongs to the TPP enzyme family
EKH77_RS00180	COG0242	peptide deformylase activity
EKH77_RS00195	COG1309	transcriptional regulator
EKH77_RS00210	COG2124	cytochrome p450
EKH77_RS00250	COG2226	methyltransferase
EKH77_RS00260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EKH77_RS00320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKH77_RS00325	COG0456	acetyltransferase
EKH77_RS00335	COG0657	acetylesterase activity
EKH77_RS00355	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EKH77_RS00390	COG4221	oxidoreductase activity
EKH77_RS00415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EKH77_RS00425	COG1597	lipid kinase activity
EKH77_RS00470	COG2313	pseudouridylate synthase activity
EKH77_RS00495	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EKH77_RS00585	COG0464	growth
EKH77_RS00595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKH77_RS00640	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EKH77_RS00645	COG1132	(ABC) transporter
EKH77_RS00660	COG2319	Wd-40 repeat
EKH77_RS00660	COG4249	Peptidase C14 caspase catalytic subunit p20
EKH77_RS00670	COG1752	Esterase of the alpha-beta hydrolase superfamily
EKH77_RS00675	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EKH77_RS00680	COG0640	Transcriptional regulator
EKH77_RS00685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKH77_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS00720	COG1309	transcriptional regulator
EKH77_RS00730	COG0154	amidase activity
EKH77_RS00770	COG1316	TRANSCRIPTIONal
EKH77_RS00800	COG2814	Major facilitator Superfamily
EKH77_RS00805	COG1316	TRANSCRIPTIONal
EKH77_RS00825	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKH77_RS00865	COG1511	domain protein
EKH77_RS00870	COG0688	phosphatidylethanolamine metabolic process
EKH77_RS00900	COG4977	sequence-specific DNA binding
EKH77_RS00920	COG0688	phosphatidylethanolamine metabolic process
EKH77_RS00935	COG1247	-acetyltransferase
EKH77_RS00945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EKH77_RS00955	COG2267	carboxylic ester hydrolase activity
EKH77_RS00985	COG1116	anion transmembrane transporter activity
EKH77_RS00990	COG0640	Transcriptional regulator
EKH77_RS01005	COG0488	(ABC) transporter
EKH77_RS01055	COG0488	(ABC) transporter
EKH77_RS01060	COG0346	lactoylglutathione lyase activity
EKH77_RS01070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EKH77_RS01080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKH77_RS01085	COG1764	response to oxidative stress
EKH77_RS01090	COG1846	Transcriptional regulator
EKH77_RS01105	COG0252	asparaginase activity
EKH77_RS01110	COG1027	Aspartate ammonia-lyase
EKH77_RS01145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EKH77_RS01190	COG2197	response regulator
EKH77_RS01195	COG4585	Histidine kinase
EKH77_RS01210	COG0657	acetylesterase activity
EKH77_RS01240	COG2070	2-Nitropropane dioxygenase
EKH77_RS01240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EKH77_RS01250	COG3321	synthase
EKH77_RS01250	COG0604	alcohol dehydrogenase
EKH77_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS01255	COG0583	DNA-binding transcription factor activity
EKH77_RS01295	COG0730	response to heat
EKH77_RS01305	COG2814	Major facilitator Superfamily
EKH77_RS01310	COG0156	8-amino-7-oxononanoate synthase activity
EKH77_RS01350	COG1113	amino acid transport
EKH77_RS01370	COG3135	benzoate transporter
EKH77_RS01385	COG0431	NADPH-dependent FMN reductase
EKH77_RS01390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EKH77_RS01410	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS01415	COG2124	cytochrome p450
EKH77_RS01425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EKH77_RS01435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKH77_RS01475	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKH77_RS01480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKH77_RS01480	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EKH77_RS01515	COG1349	DNA-binding transcription factor activity
EKH77_RS01525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKH77_RS01525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKH77_RS01525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKH77_RS01545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EKH77_RS01555	COG2340	Cysteine-rich secretory protein family
EKH77_RS01585	COG1309	transcriptional regulator
EKH77_RS01610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKH77_RS01625	COG4221	oxidoreductase activity
EKH77_RS01645	COG0693	protein deglycase activity
EKH77_RS01700	COG2957	Belongs to the agmatine deiminase family
EKH77_RS01710	COG0387	Pfam Sodium calcium exchanger
EKH77_RS01715	COG3268	Saccharopine dehydrogenase
EKH77_RS01720	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS01725	COG1982	Orn Lys Arg decarboxylase major
EKH77_RS01775	COG1595	DNA-templated transcription, initiation
EKH77_RS01790	COG0583	DNA-binding transcription factor activity
EKH77_RS01800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKH77_RS01800	COG2146	nitrite reductase [NAD(P)H] activity
EKH77_RS01805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKH77_RS01810	COG0243	molybdopterin cofactor binding
EKH77_RS01815	COG0745	RESPONSE REGULATOR receiver
EKH77_RS01825	COG3189	MarR family transcriptional regulator
EKH77_RS01830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKH77_RS01900	COG1396	sequence-specific DNA binding
EKH77_RS01945	COG4585	Histidine kinase
EKH77_RS01950	COG2197	response regulator
EKH77_RS01960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EKH77_RS01970	COG0477	Major facilitator Superfamily
EKH77_RS02015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EKH77_RS02035	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS02040	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EKH77_RS02105	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EKH77_RS02115	COG2234	aminopeptidase activity
EKH77_RS02135	COG1131	(ABC) transporter
EKH77_RS02140	COG3559	Exporter of polyketide antibiotics
EKH77_RS02190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EKH77_RS02215	COG3321	synthase
EKH77_RS02215	COG0604	alcohol dehydrogenase
EKH77_RS02220	COG2890	protein-(glutamine-N5) methyltransferase activity
EKH77_RS02245	COG0604	alcohol dehydrogenase
EKH77_RS02245	COG3321	synthase
EKH77_RS02255	COG0604	alcohol dehydrogenase
EKH77_RS02255	COG3321	synthase
EKH77_RS02260	COG0604	alcohol dehydrogenase
EKH77_RS02260	COG3321	synthase
EKH77_RS02275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EKH77_RS02495	COG0596	Alpha beta hydrolase
EKH77_RS02520	COG0659	secondary active sulfate transmembrane transporter activity
EKH77_RS02535	COG2824	Alkylphosphonate utilization operon protein PhnA
EKH77_RS02595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EKH77_RS02600	COG1733	regulation of RNA biosynthetic process
EKH77_RS02605	COG0252	asparaginase activity
EKH77_RS02615	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKH77_RS02620	COG0328	RNA-DNA hybrid ribonuclease activity
EKH77_RS02625	COG0277	FAD linked oxidase domain protein
EKH77_RS02640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKH77_RS02650	COG0300	oxidoreductase activity
EKH77_RS02660	COG2409	Drug exporters of the RND superfamily
EKH77_RS02670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKH77_RS02680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKH77_RS02730	COG3953	SLT domain
EKH77_RS02730	COG5280	Phage tail tape measure protein TP901
EKH77_RS03005	COG1796	DNA polymerase
EKH77_RS03005	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EKH77_RS03045	COG1063	alcohol dehydrogenase
EKH77_RS03050	COG0156	8-amino-7-oxononanoate synthase activity
EKH77_RS03065	COG2197	response regulator
EKH77_RS03075	COG0076	glutamate decarboxylase activity
EKH77_RS03080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EKH77_RS03165	COG2319	Wd-40 repeat
EKH77_RS03165	COG4249	Peptidase C14 caspase catalytic subunit p20
EKH77_RS03170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKH77_RS03180	COG2815	serine threonine protein kinase
EKH77_RS03180	COG0515	serine threonine protein kinase
EKH77_RS03195	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS03220	COG3227	Zinc metalloprotease (Elastase)
EKH77_RS03230	COG0842	Transport permease protein
EKH77_RS03230	COG1716	ATPase activity
EKH77_RS03230	COG1131	(ABC) transporter
EKH77_RS03265	COG0477	Major facilitator Superfamily
EKH77_RS03270	COG2770	Histidine kinase
EKH77_RS03270	COG2208	phosphoserine phosphatase activity
EKH77_RS03275	COG4977	sequence-specific DNA binding
EKH77_RS03280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKH77_RS03310	COG3795	YCII-related domain
EKH77_RS03315	COG4941	Belongs to the sigma-70 factor family
EKH77_RS03325	COG0583	DNA-binding transcription factor activity
EKH77_RS03375	COG2011	ABC-type metal ion transport system permease component
EKH77_RS03380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKH77_RS03395	COG2197	response regulator
EKH77_RS03410	COG0515	serine threonine protein kinase
EKH77_RS03415	COG0515	serine threonine protein kinase
EKH77_RS03420	COG0515	serine threonine protein kinase
EKH77_RS03430	COG0477	Major facilitator Superfamily
EKH77_RS03460	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKH77_RS03465	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EKH77_RS03495	COG3012	SEC-C Motif Domain Protein
EKH77_RS03510	COG0791	NLP P60 protein
EKH77_RS03530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EKH77_RS03535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKH77_RS03545	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS03600	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS03625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EKH77_RS03640	COG0367	asparagine synthase
EKH77_RS03650	COG2423	ornithine cyclodeaminase activity
EKH77_RS03655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EKH77_RS03730	COG3261	NADH dehydrogenase
EKH77_RS03730	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EKH77_RS03735	COG0651	ATP synthesis coupled electron transport
EKH77_RS03745	COG0650	Formate hydrogenlyase subunit 4
EKH77_RS03755	COG3260	NADH ubiquinone oxidoreductase 20
EKH77_RS03785	COG2124	cytochrome p450
EKH77_RS03830	COG1793	dna ligase
EKH77_RS03905	COG1024	Enoyl-CoA hydratase
EKH77_RS03930	COG2366	antibiotic biosynthetic process
EKH77_RS03940	COG2070	2-Nitropropane dioxygenase
EKH77_RS03945	COG0515	serine threonine protein kinase
EKH77_RS03960	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS03975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EKH77_RS03990	COG0667	Aldo Keto reductase
EKH77_RS04050	COG2376	Dihydroxyacetone kinase
EKH77_RS04065	COG1051	belongs to the nudix hydrolase family
EKH77_RS04080	COG1215	transferase activity, transferring glycosyl groups
EKH77_RS04105	COG0464	growth
EKH77_RS04110	COG1349	DNA-binding transcription factor activity
EKH77_RS04130	COG1940	carbohydrate kinase activity
EKH77_RS04135	COG2223	nitrite transmembrane transporter activity
EKH77_RS04145	COG0445	tRNA wobble uridine modification
EKH77_RS04225	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EKH77_RS04325	COG3757	hydrolase, family 25
EKH77_RS04325	COG3409	Peptidoglycan-binding domain 1 protein
EKH77_RS04375	COG1796	DNA polymerase
EKH77_RS04375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EKH77_RS04385	COG1793	dna ligase
EKH77_RS04385	COG3285	dna ligase
EKH77_RS04390	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EKH77_RS04395	COG1672	PFAM Archaeal ATPase
EKH77_RS04395	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EKH77_RS04430	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EKH77_RS04445	COG2318	DinB family
EKH77_RS04455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKH77_RS04490	COG0667	Aldo Keto reductase
EKH77_RS04500	COG1819	glycosyl
EKH77_RS04505	COG2124	cytochrome p450
EKH77_RS04545	COG2124	cytochrome p450
EKH77_RS04560	COG3510	cephalosporin hydroxylase
EKH77_RS04565	COG1819	glycosyl
EKH77_RS04570	COG2226	methyltransferase
EKH77_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS04620	COG1335	isochorismatase
EKH77_RS04635	COG0583	DNA-binding transcription factor activity
EKH77_RS04640	COG0697	spore germination
EKH77_RS04655	COG0697	spore germination
EKH77_RS04665	COG1472	Belongs to the glycosyl hydrolase 3 family
EKH77_RS04670	COG1695	Transcriptional regulator
EKH77_RS04685	COG0702	epimerase
EKH77_RS04725	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKH77_RS04725	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKH77_RS04735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKH77_RS04755	COG1716	ATPase activity
EKH77_RS04775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EKH77_RS04810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKH77_RS04820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EKH77_RS04830	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EKH77_RS04845	COG2018	Roadblock/LC7 domain
EKH77_RS04890	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EKH77_RS04895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EKH77_RS04900	COG1984	allophanate hydrolase subunit 2
EKH77_RS04905	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS04935	COG0745	RESPONSE REGULATOR receiver
EKH77_RS04945	COG0772	Belongs to the SEDS family
EKH77_RS04950	COG1793	dna ligase
EKH77_RS04985	COG3030	protein affecting phage T7 exclusion by the F plasmid
EKH77_RS04990	COG0463	Glycosyl transferase, family 2
EKH77_RS05015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EKH77_RS05020	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS05050	COG0662	Cupin 2, conserved barrel domain protein
EKH77_RS05055	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS05065	COG2076	Multidrug Resistance protein
EKH77_RS05070	COG2076	Multidrug Resistance protein
EKH77_RS05100	COG3835	regulator
EKH77_RS05125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKH77_RS05130	COG1120	ATPase activity
EKH77_RS05155	COG2124	cytochrome p450
EKH77_RS05200	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS05210	COG2066	Belongs to the glutaminase family
EKH77_RS05220	COG2267	carboxylic ester hydrolase activity
EKH77_RS05250	COG5001	Diguanylate cyclase
EKH77_RS05285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EKH77_RS05290	COG0140	phosphoribosyl-ATP diphosphatase activity
EKH77_RS05295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EKH77_RS05300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EKH77_RS05300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EKH77_RS05305	COG3201	nicotinamide mononucleotide transporter
EKH77_RS05325	COG0738	Major facilitator superfamily
EKH77_RS05335	COG2233	PERMEase
EKH77_RS05350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKH77_RS05375	COG0531	amino acid
EKH77_RS05385	COG2390	Transcriptional regulator
EKH77_RS05390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EKH77_RS05400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EKH77_RS05435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EKH77_RS05450	COG0194	GDP metabolic process
EKH77_RS05460	COG0284	orotidine-5'-phosphate decarboxylase activity
EKH77_RS05470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EKH77_RS05475	COG0505	Belongs to the CarA family
EKH77_RS05485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EKH77_RS05495	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EKH77_RS05505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKH77_RS05510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKH77_RS05515	COG0006	proline dipeptidase activity
EKH77_RS05525	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EKH77_RS05530	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EKH77_RS05535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EKH77_RS05540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EKH77_RS05560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKH77_RS05575	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EKH77_RS05595	COG0124	histidyl-tRNA synthetase
EKH77_RS05605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EKH77_RS05610	COG1196	nuclear chromosome segregation
EKH77_RS05615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKH77_RS05620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKH77_RS05625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKH77_RS05630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKH77_RS05640	COG2255	four-way junction helicase activity
EKH77_RS05645	COG0632	four-way junction helicase activity
EKH77_RS05650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EKH77_RS05655	COG0217	transcriptional regulatory protein
EKH77_RS05660	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EKH77_RS05665	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EKH77_RS05680	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS05685	COG1560	Kdo2-lipid A biosynthetic process
EKH77_RS05690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKH77_RS05720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKH77_RS05735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EKH77_RS05790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKH77_RS05840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EKH77_RS05840	COG1648	precorrin-2 dehydrogenase activity
EKH77_RS05860	COG1464	Belongs to the NlpA lipoprotein family
EKH77_RS05865	COG2011	ABC-type metal ion transport system permease component
EKH77_RS05870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKH77_RS05905	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EKH77_RS05910	COG0477	Major facilitator Superfamily
EKH77_RS05920	COG0165	Argininosuccinate lyase
EKH77_RS05925	COG0137	argininosuccinate synthase activity
EKH77_RS05940	COG1438	arginine binding
EKH77_RS05945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EKH77_RS05950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EKH77_RS05955	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EKH77_RS05960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EKH77_RS05990	COG1649	PFAM Uncharacterised BCR, COG1649
EKH77_RS06020	COG0072	phenylalanine-tRNA ligase activity
EKH77_RS06020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKH77_RS06025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EKH77_RS06030	COG5002	protein histidine kinase activity
EKH77_RS06035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKH77_RS06040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EKH77_RS06045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EKH77_RS06050	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EKH77_RS06065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EKH77_RS06105	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS06115	COG2186	Transcriptional regulator
EKH77_RS06120	COG0531	amino acid
EKH77_RS06125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EKH77_RS06145	COG4176	ABC-type proline glycine betaine transport system permease component
EKH77_RS06150	COG4175	Glycine betaine
EKH77_RS06150	COG0517	IMP dehydrogenase activity
EKH77_RS06155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKH77_RS06180	COG0805	protein transport
EKH77_RS06185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKH77_RS06220	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EKH77_RS06235	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EKH77_RS06240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EKH77_RS06250	COG4122	O-methyltransferase activity
EKH77_RS06255	COG1222	aaa ATPase
EKH77_RS06280	COG1994	Peptidase M50
EKH77_RS06280	COG0517	IMP dehydrogenase activity
EKH77_RS06290	COG2197	response regulator
EKH77_RS06300	COG4166	transmembrane transport
EKH77_RS06320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EKH77_RS06325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EKH77_RS06330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EKH77_RS06335	COG1414	Transcriptional regulator
EKH77_RS06340	COG1410	methionine synthase
EKH77_RS06340	COG0646	methionine synthase
EKH77_RS06365	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS06375	COG0215	cysteine-tRNA ligase activity
EKH77_RS06395	COG0598	Magnesium transport protein CorA
EKH77_RS06405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKH77_RS06410	COG0667	Aldo Keto reductase
EKH77_RS06440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EKH77_RS06470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EKH77_RS06480	COG0477	Major facilitator Superfamily
EKH77_RS06485	COG1846	Transcriptional regulator
EKH77_RS06505	COG1309	transcriptional regulator
EKH77_RS06535	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EKH77_RS06540	COG2188	Transcriptional regulator
EKH77_RS06550	COG0515	serine threonine protein kinase
EKH77_RS06555	COG2755	lipolytic protein G-D-S-L family
EKH77_RS06570	COG0463	Glycosyl transferase, family 2
EKH77_RS06575	COG1216	Glycosyl transferase, family 2
EKH77_RS06645	COG1725	Transcriptional regulator
EKH77_RS06650	COG0367	asparagine synthase
EKH77_RS06675	COG0587	DNA-directed DNA polymerase activity
EKH77_RS06715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKH77_RS06730	COG1799	cell septum assembly
EKH77_RS06735	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS06740	COG0477	Major facilitator Superfamily
EKH77_RS06750	COG0671	phosphoesterase, PA-phosphatase related
EKH77_RS06760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKH77_RS06770	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS06785	COG1160	GTP binding
EKH77_RS06795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EKH77_RS06810	COG1187	pseudouridine synthase activity
EKH77_RS06815	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EKH77_RS06820	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EKH77_RS06835	COG0686	Belongs to the AlaDH PNT family
EKH77_RS06845	COG0494	nUDIX hydrolase
EKH77_RS06850	COG0504	CTP synthase activity
EKH77_RS06855	COG3387	PFAM Glycoside hydrolase 15-related
EKH77_RS06860	COG2814	Major facilitator Superfamily
EKH77_RS06885	COG0497	DNA recombination
EKH77_RS06895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKH77_RS06915	COG1120	ATPase activity
EKH77_RS06920	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKH77_RS06925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKH77_RS06935	COG2375	cellular response to nickel ion
EKH77_RS06940	COG0647	UMP catabolic process
EKH77_RS06980	COG2094	Belongs to the DNA glycosylase MPG family
EKH77_RS06990	COG2732	(Barnase) inhibitor
EKH77_RS06995	COG4290	ribonuclease
EKH77_RS07000	COG1881	PFAM PEBP family protein
EKH77_RS07020	COG1119	ATPase activity
EKH77_RS07040	COG2197	response regulator
EKH77_RS07060	COG0842	Transport permease protein
EKH77_RS07060	COG1131	(ABC) transporter
EKH77_RS07060	COG1716	ATPase activity
EKH77_RS07065	COG3830	Belongs to the UPF0237 family
EKH77_RS07065	COG0560	Phosphoserine phosphatase
EKH77_RS07085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EKH77_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS07095	COG1357	PFAM Pentapeptide repeats (8 copies)
EKH77_RS07110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKH77_RS07115	COG2261	transglycosylase associated protein
EKH77_RS07130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EKH77_RS07135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKH77_RS07175	COG3387	PFAM Glycoside hydrolase 15-related
EKH77_RS07195	COG0235	Class ii aldolase
EKH77_RS07220	COG0488	(ABC) transporter
EKH77_RS07230	COG1024	Enoyl-CoA hydratase
EKH77_RS07260	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EKH77_RS07265	COG1492	cobalamin metabolic process
EKH77_RS07275	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EKH77_RS07280	COG1797	cobyrinic acid a,c-diamide synthase activity
EKH77_RS07305	COG4585	Histidine kinase
EKH77_RS07310	COG2197	response regulator
EKH77_RS07325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKH77_RS07340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKH77_RS07345	COG2171	N-acyltransferase activity
EKH77_RS07350	COG1404	Belongs to the peptidase S8 family
EKH77_RS07355	COG2957	Belongs to the agmatine deiminase family
EKH77_RS07365	COG0822	iron-sulfur transferase activity
EKH77_RS07370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKH77_RS07375	COG0396	ATPase activity
EKH77_RS07385	COG0719	Fe-S assembly protein
EKH77_RS07410	COG1612	heme a metabolic process
EKH77_RS07425	COG0109	protoheme IX farnesyltransferase activity
EKH77_RS07440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EKH77_RS07455	COG0363	glucosamine-6-phosphate deaminase activity
EKH77_RS07460	COG0166	Belongs to the GPI family
EKH77_RS07470	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EKH77_RS07475	COG0149	triose-phosphate isomerase activity
EKH77_RS07480	COG0126	phosphoglycerate kinase activity
EKH77_RS07485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EKH77_RS07495	COG1481	regulation of sporulation
EKH77_RS07500	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EKH77_RS07505	COG1660	Displays ATPase and GTPase activities
EKH77_RS07510	COG0322	excinuclease ABC activity
EKH77_RS07535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EKH77_RS07550	COG0477	Major facilitator Superfamily
EKH77_RS07570	COG0556	nucleotide-excision repair
EKH77_RS07575	COG0584	glycerophosphoryl diester phosphodiesterase
EKH77_RS07580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKH77_RS07610	COG0237	dephospho-CoA kinase activity
EKH77_RS07620	COG0539	negative regulation of cytoplasmic translation
EKH77_RS07630	COG2226	methyltransferase
EKH77_RS07635	COG1643	Atp-dependent helicase
EKH77_RS07665	COG2050	protein possibly involved in aromatic compounds catabolism
EKH77_RS07720	COG0737	Belongs to the 5'-nucleotidase family
EKH77_RS07730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKH77_RS07735	COG0287	Prephenate dehydrogenase
EKH77_RS07735	COG1605	Chorismate mutase
EKH77_RS07750	COG1470	cell adhesion involved in biofilm formation
EKH77_RS07750	COG0366	Alpha amylase catalytic
EKH77_RS07765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKH77_RS07775	COG2197	response regulator
EKH77_RS07800	COG1215	transferase activity, transferring glycosyl groups
EKH77_RS07805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EKH77_RS07830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EKH77_RS07845	COG0159	tryptophan synthase activity
EKH77_RS07850	COG0133	tryptophan synthase activity
EKH77_RS07860	COG0134	indole-3-glycerol-phosphate synthase activity
EKH77_RS07880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKH77_RS07885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EKH77_RS07895	COG2259	Doxx family
EKH77_RS07900	COG0107	imidazoleglycerol-phosphate synthase activity
EKH77_RS07905	COG0251	oxidation-reduction process
EKH77_RS07910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EKH77_RS07915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EKH77_RS07920	COG0131	Imidazoleglycerol-phosphate dehydratase
EKH77_RS07925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKH77_RS07930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EKH77_RS07940	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EKH77_RS07965	COG1432	Conserved Protein
EKH77_RS07970	COG0587	DNA-directed DNA polymerase activity
EKH77_RS08040	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKH77_RS08045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EKH77_RS08050	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EKH77_RS08065	COG1799	cell septum assembly
EKH77_RS08080	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EKH77_RS08085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EKH77_RS08090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKH77_RS08100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EKH77_RS08105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKH77_RS08115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKH77_RS08120	COG0768	penicillin binding
EKH77_RS08130	COG0275	rRNA processing
EKH77_RS08140	COG0714	Associated with various cellular activities
EKH77_RS08165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EKH77_RS08175	COG1309	transcriptional regulator
EKH77_RS08200	COG0352	thiamine-phosphate diphosphorylase activity
EKH77_RS08210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKH77_RS08215	COG2022	thiamine diphosphate biosynthetic process
EKH77_RS08215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKH77_RS08225	COG2022	thiamine diphosphate biosynthetic process
EKH77_RS08230	COG0515	serine threonine protein kinase
EKH77_RS08230	COG2815	serine threonine protein kinase
EKH77_RS08235	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EKH77_RS08240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EKH77_RS08245	COG2193	ferroxidase activity
EKH77_RS08250	COG0243	molybdopterin cofactor binding
EKH77_RS08255	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EKH77_RS08265	COG0205	6-phosphofructokinase activity
EKH77_RS08300	COG1940	carbohydrate kinase activity
EKH77_RS08310	COG0003	Pfam Anion-transporting ATPase
EKH77_RS08330	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS08345	COG0791	NLP P60 protein
EKH77_RS08365	COG0705	Rhomboid family
EKH77_RS08375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKH77_RS08380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EKH77_RS08385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EKH77_RS08390	COG0723	plastoquinol--plastocyanin reductase activity
EKH77_RS08395	COG2010	Cytochrome c
EKH77_RS08400	COG1845	cytochrome c oxidase, subunit III
EKH77_RS08410	COG1376	ErfK ybiS ycfS ynhG family protein
EKH77_RS08420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKH77_RS08425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EKH77_RS08435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKH77_RS08455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EKH77_RS08490	COG4585	Histidine kinase
EKH77_RS08495	COG2197	response regulator
EKH77_RS08500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EKH77_RS08505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EKH77_RS08505	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKH77_RS08520	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EKH77_RS08525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKH77_RS08530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKH77_RS08535	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKH77_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS08575	COG0321	lipoyl(octanoyl) transferase activity
EKH77_RS08580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EKH77_RS08605	COG0702	epimerase
EKH77_RS08615	COG0640	Transcriptional regulator
EKH77_RS08630	COG0745	RESPONSE REGULATOR receiver
EKH77_RS08645	COG2197	response regulator
EKH77_RS08655	COG2365	Tyrosine phosphatase family
EKH77_RS08680	COG1609	Transcriptional regulator
EKH77_RS08685	COG0366	Alpha amylase catalytic
EKH77_RS08690	COG3833	ABC-type maltose transport systems, permease component
EKH77_RS08720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EKH77_RS08725	COG0174	glutamine synthetase
EKH77_RS08735	COG2267	carboxylic ester hydrolase activity
EKH77_RS08740	COG0531	amino acid
EKH77_RS08750	COG2132	Multicopper oxidase
EKH77_RS08765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKH77_RS08765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EKH77_RS08795	COG2814	Major facilitator Superfamily
EKH77_RS08805	COG1309	transcriptional regulator
EKH77_RS08810	COG0477	Major facilitator Superfamily
EKH77_RS08815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EKH77_RS08835	COG1994	Peptidase M50
EKH77_RS08885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKH77_RS08890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKH77_RS08895	COG1120	ATPase activity
EKH77_RS08905	COG2837	iron assimilation
EKH77_RS08910	COG0672	)-iron permease
EKH77_RS08930	COG1834	amidinotransferase
EKH77_RS08945	COG2814	Major facilitator Superfamily
EKH77_RS08950	COG0384	phenazine biosynthesis protein PhzF
EKH77_RS09020	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS09030	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS09050	COG3227	Zinc metalloprotease (Elastase)
EKH77_RS09070	COG3022	response to hydroperoxide
EKH77_RS09075	COG0800	Aldolase
EKH77_RS09110	COG2197	response regulator
EKH77_RS09125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EKH77_RS09130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKH77_RS09150	COG2030	dehydratase
EKH77_RS09155	COG4585	Histidine kinase
EKH77_RS09160	COG2197	response regulator
EKH77_RS09170	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKH77_RS09180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKH77_RS09210	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS09215	COG1309	transcriptional regulator
EKH77_RS09220	COG2197	response regulator
EKH77_RS09230	COG1132	(ABC) transporter
EKH77_RS09245	COG0515	serine threonine protein kinase
EKH77_RS09250	COG0702	epimerase
EKH77_RS09300	COG3845	ABC transporter
EKH77_RS09315	COG2124	cytochrome p450
EKH77_RS09325	COG0183	Belongs to the thiolase family
EKH77_RS09380	COG1660	Displays ATPase and GTPase activities
EKH77_RS09390	COG2188	Transcriptional regulator
EKH77_RS09430	COG5640	endopeptidase activity
EKH77_RS09435	COG0583	DNA-binding transcription factor activity
EKH77_RS09450	COG3655	Transcriptional regulator
EKH77_RS09535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EKH77_RS09545	COG0477	Major facilitator Superfamily
EKH77_RS09565	COG4585	Histidine kinase
EKH77_RS09570	COG2197	response regulator
EKH77_RS09585	COG1285	pathogenesis
EKH77_RS09600	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EKH77_RS09605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKH77_RS09610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKH77_RS09615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKH77_RS09620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EKH77_RS09640	COG0789	Transcriptional regulator
EKH77_RS09645	COG0667	Aldo Keto reductase
EKH77_RS09655	COG2130	NADP-dependent
EKH77_RS09665	COG1335	isochorismatase
EKH77_RS09685	COG0406	alpha-ribazole phosphatase activity
EKH77_RS09690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKH77_RS09715	COG1070	Carbohydrate kinase
EKH77_RS09725	COG0358	DNA primase activity
EKH77_RS09735	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EKH77_RS09740	COG2949	membrane
EKH77_RS09765	COG0531	amino acid
EKH77_RS09795	COG2182	Extracellular solute-binding protein
EKH77_RS09805	COG0395	ABC-type sugar transport system, permease component
EKH77_RS09815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKH77_RS09815	COG0574	Belongs to the PEP-utilizing enzyme family
EKH77_RS09830	COG0477	Major facilitator Superfamily
EKH77_RS09835	COG0667	Aldo Keto reductase
EKH77_RS09840	COG1309	transcriptional regulator
EKH77_RS09845	COG2197	response regulator
EKH77_RS09860	COG0423	glycine-tRNA ligase activity
EKH77_RS09865	COG3443	Belongs to the bacterial solute-binding protein 9 family
EKH77_RS09865	COG0803	Belongs to the bacterial solute-binding protein 9 family
EKH77_RS09870	COG1121	(ABC) transporter
EKH77_RS09875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EKH77_RS09895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKH77_RS09900	COG1381	Involved in DNA repair and RecF pathway recombination
EKH77_RS09920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKH77_RS09940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EKH77_RS09970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EKH77_RS09980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKH77_RS09985	COG1486	melibiose metabolic process
EKH77_RS10020	COG1234	tRNA 3'-trailer cleavage
EKH77_RS10025	COG0537	adenosine 5'-monophosphoramidase activity
EKH77_RS10070	COG1733	regulation of RNA biosynthetic process
EKH77_RS10095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EKH77_RS10120	COG2814	Major facilitator Superfamily
EKH77_RS10160	COG0484	heat shock protein binding
EKH77_RS10165	COG1420	regulation of RNA biosynthetic process
EKH77_RS10190	COG1022	Amp-dependent synthetase and ligase
EKH77_RS10195	COG0481	GTPase activity
EKH77_RS10200	COG0268	Binds directly to 16S ribosomal RNA
EKH77_RS10225	COG1555	photosystem II stabilization
EKH77_RS10225	COG1596	polysaccharide export
EKH77_RS10230	COG1307	EDD domain protein, DegV family
EKH77_RS10240	COG0495	leucyl-tRNA aminoacylation
EKH77_RS10280	COG0588	phosphoglycerate mutase activity
EKH77_RS10285	COG0799	negative regulation of ribosome biogenesis
EKH77_RS10295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EKH77_RS10300	COG0501	Belongs to the peptidase M48B family
EKH77_RS10315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EKH77_RS10325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKH77_RS10335	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EKH77_RS10340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EKH77_RS10345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EKH77_RS10350	COG1530	ribonuclease E activity
EKH77_RS10365	COG5607	PFAM CHAD domain containing protein
EKH77_RS10365	COG3025	triphosphatase activity
EKH77_RS10370	COG0772	Belongs to the SEDS family
EKH77_RS10375	COG0768	penicillin binding
EKH77_RS10390	COG1077	Cell shape determining protein MreB Mrl
EKH77_RS10395	COG0105	UTP biosynthetic process
EKH77_RS10405	COG0285	dihydrofolate synthase activity
EKH77_RS10410	COG2205	protein histidine kinase activity
EKH77_RS10410	COG2202	Pas domain
EKH77_RS10415	COG0745	RESPONSE REGULATOR receiver
EKH77_RS10425	COG1215	transferase activity, transferring glycosyl groups
EKH77_RS10435	COG0525	valine-tRNA ligase activity
EKH77_RS10460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EKH77_RS10465	COG0740	serine-type endopeptidase activity
EKH77_RS10470	COG0740	serine-type endopeptidase activity
EKH77_RS10475	COG0544	peptidyl-prolyl cis-trans isomerase activity
EKH77_RS10500	COG1674	ftsk spoiiie
EKH77_RS10575	COG1733	regulation of RNA biosynthetic process
EKH77_RS10595	COG3629	intracellular signal transduction
EKH77_RS10595	COG3903	Transcriptional regulator
EKH77_RS10605	COG3629	intracellular signal transduction
EKH77_RS10615	COG4552	Acetyltransferase involved in intracellular survival and related
EKH77_RS10630	COG1113	amino acid transport
EKH77_RS10640	COG1113	amino acid transport
EKH77_RS10645	COG1113	amino acid transport
EKH77_RS10650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EKH77_RS10665	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EKH77_RS10725	COG3291	Pkd domain containing protein
EKH77_RS10725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EKH77_RS10735	COG0668	transmembrane transport
EKH77_RS10745	COG1846	Transcriptional regulator
EKH77_RS10745	COG1940	carbohydrate kinase activity
EKH77_RS10755	COG1175	transmembrane transport
EKH77_RS10760	COG0395	ABC-type sugar transport system, permease component
EKH77_RS10765	COG1486	melibiose metabolic process
EKH77_RS10790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EKH77_RS10800	COG0515	serine threonine protein kinase
EKH77_RS10845	COG0629	single-stranded DNA binding
EKH77_RS10920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKH77_RS10925	COG1993	acr, cog1993
EKH77_RS10930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKH77_RS10935	COG0583	DNA-binding transcription factor activity
EKH77_RS10945	COG1053	succinate dehydrogenase
EKH77_RS10955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EKH77_RS10970	COG3548	integral membrane protein
EKH77_RS10980	COG1132	(ABC) transporter
EKH77_RS11015	COG3226	Transcriptional regulator
EKH77_RS11020	COG1289	transmembrane transporter activity
EKH77_RS11030	COG3962	Belongs to the TPP enzyme family
EKH77_RS11035	COG3718	enzyme involved in inositol metabolism
EKH77_RS11045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKH77_RS11050	COG1082	Xylose isomerase domain protein TIM barrel
EKH77_RS11055	COG0673	inositol 2-dehydrogenase activity
EKH77_RS11060	COG0673	inositol 2-dehydrogenase activity
EKH77_RS11080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EKH77_RS11095	COG0583	DNA-binding transcription factor activity
EKH77_RS11120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EKH77_RS11155	COG1946	Acyl-CoA thioesterase
EKH77_RS11165	COG1309	transcriptional regulator
EKH77_RS11170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EKH77_RS11185	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS11200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EKH77_RS11205	COG0589	response to stress
EKH77_RS11215	COG4977	sequence-specific DNA binding
EKH77_RS11220	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EKH77_RS11230	COG1278	Cold shock
EKH77_RS11270	COG0406	alpha-ribazole phosphatase activity
EKH77_RS11320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKH77_RS11345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EKH77_RS11345	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EKH77_RS11350	COG0785	Cytochrome C biogenesis protein
EKH77_RS11360	COG0741	lytic transglycosylase activity
EKH77_RS11360	COG0791	NLP P60 protein
EKH77_RS11420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EKH77_RS11425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKH77_RS11430	COG2188	Transcriptional regulator
EKH77_RS11445	COG0673	inositol 2-dehydrogenase activity
EKH77_RS11490	COG0706	membrane insertase activity
EKH77_RS11500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKH77_RS11510	COG2733	membrane
EKH77_RS11525	COG1131	(ABC) transporter
EKH77_RS11550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EKH77_RS11565	COG2205	protein histidine kinase activity
EKH77_RS11590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EKH77_RS11595	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EKH77_RS11600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKH77_RS11605	COG1263	PTS System
EKH77_RS11610	COG1263	PTS System
EKH77_RS11615	COG1234	tRNA 3'-trailer cleavage
EKH77_RS11640	COG1113	amino acid transport
EKH77_RS11650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EKH77_RS11660	COG1335	isochorismatase
EKH77_RS11695	COG0277	FAD linked oxidase domain protein
EKH77_RS11700	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EKH77_RS11740	COG2855	membrane
EKH77_RS11750	COG0583	DNA-binding transcription factor activity
EKH77_RS11850	COG1404	Belongs to the peptidase S8 family
EKH77_RS11860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EKH77_RS11875	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EKH77_RS11880	COG0395	ABC-type sugar transport system, permease component
EKH77_RS11885	COG1175	transmembrane transport
EKH77_RS11890	COG2182	Extracellular solute-binding protein
EKH77_RS11900	COG1678	Uncharacterized ACR, COG1678
EKH77_RS11905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKH77_RS11910	COG0776	regulation of translation
EKH77_RS11925	COG3973	AAA domain
EKH77_RS11960	COG0655	NAD(P)H dehydrogenase (quinone) activity
EKH77_RS11965	COG0583	DNA-binding transcription factor activity
EKH77_RS11990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EKH77_RS11995	COG0793	Belongs to the peptidase S41A family
EKH77_RS12005	COG2884	Cell division ATP-binding protein ftsE
EKH77_RS12020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EKH77_RS12025	COG0515	serine threonine protein kinase
EKH77_RS12030	COG0515	serine threonine protein kinase
EKH77_RS12045	COG1653	transport
EKH77_RS12050	COG1175	transmembrane transport
EKH77_RS12055	COG0395	ABC-type sugar transport system, permease component
EKH77_RS12065	COG1215	transferase activity, transferring glycosyl groups
EKH77_RS12075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKH77_RS12090	COG0463	Glycosyl transferase, family 2
EKH77_RS12110	COG2902	Dehydrogenase
EKH77_RS12130	COG0653	protein targeting
EKH77_RS12145	COG2197	response regulator
EKH77_RS12150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EKH77_RS12160	COG0823	Involved in the tonB-independent uptake of proteins
EKH77_RS12165	COG5002	protein histidine kinase activity
EKH77_RS12165	COG5000	phosphorelay sensor kinase activity
EKH77_RS12170	COG0745	RESPONSE REGULATOR receiver
EKH77_RS12175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EKH77_RS12210	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EKH77_RS12215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKH77_RS12215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKH77_RS12215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKH77_RS12225	COG1482	cell wall glycoprotein biosynthetic process
EKH77_RS12235	COG2835	tetraacyldisaccharide 4'-kinase activity
EKH77_RS12240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKH77_RS12280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EKH77_RS12285	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EKH77_RS12285	COG0778	Nitroreductase
EKH77_RS12310	COG1316	TRANSCRIPTIONal
EKH77_RS12315	COG1316	TRANSCRIPTIONal
EKH77_RS12360	COG1316	TRANSCRIPTIONal
EKH77_RS12370	COG1316	TRANSCRIPTIONal
EKH77_RS12385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKH77_RS12410	COG2205	protein histidine kinase activity
EKH77_RS12415	COG0745	RESPONSE REGULATOR receiver
EKH77_RS12420	COG3104	oligopeptide transport
EKH77_RS12445	COG1366	Belongs to the anti-sigma-factor antagonist family
EKH77_RS12450	COG1191	sigma factor activity
EKH77_RS12490	COG1228	amidohydrolase
EKH77_RS12505	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EKH77_RS12530	COG0318	PFAM AMP-dependent synthetase and ligase
EKH77_RS12545	COG2755	lipolytic protein G-D-S-L family
EKH77_RS12550	COG0183	Belongs to the thiolase family
EKH77_RS12580	COG1136	(ABC) transporter
EKH77_RS12585	COG0577	efflux transmembrane transporter activity
EKH77_RS12590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EKH77_RS12595	COG1252	NADH dehydrogenase
EKH77_RS12650	COG0148	phosphopyruvate hydratase activity
EKH77_RS12660	COG1652	LysM domain
EKH77_RS12665	COG2124	cytochrome p450
EKH77_RS12695	COG0577	efflux transmembrane transporter activity
EKH77_RS12700	COG1136	(ABC) transporter
EKH77_RS12735	COG3547	Transposase (IS116 IS110 IS902 family)
EKH77_RS12755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EKH77_RS12760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKH77_RS12770	COG0193	aminoacyl-tRNA hydrolase activity
EKH77_RS12775	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EKH77_RS12785	COG1309	transcriptional regulator
EKH77_RS12790	COG4106	trans-aconitate 2-methyltransferase activity
EKH77_RS12800	COG2197	response regulator
EKH77_RS12810	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EKH77_RS12845	COG0488	(ABC) transporter
EKH77_RS12855	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EKH77_RS12860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EKH77_RS12865	COG3583	domain protein
EKH77_RS12865	COG3584	3D domain protein
EKH77_RS12870	COG0084	hydrolase, TatD family'
EKH77_RS12925	COG1725	Transcriptional regulator
EKH77_RS12940	COG1122	ATPase activity
EKH77_RS12950	COG0310	cobalt ion transport
EKH77_RS12965	COG2409	Drug exporters of the RND superfamily
EKH77_RS12975	COG4946	Tricorn protease homolog
EKH77_RS12975	COG0793	Belongs to the peptidase S41A family
EKH77_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS12990	COG2072	flavoprotein involved in K transport
EKH77_RS12995	COG0789	Transcriptional regulator
EKH77_RS13020	COG2205	protein histidine kinase activity
EKH77_RS13060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKH77_RS13065	COG0521	Mo-molybdopterin cofactor biosynthetic process
EKH77_RS13065	COG0315	cyclic pyranopterin monophosphate synthase activity
EKH77_RS13070	COG0315	cyclic pyranopterin monophosphate synthase activity
EKH77_RS13080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EKH77_RS13085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKH77_RS13095	COG3263	regulation of cellular component size
EKH77_RS13110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EKH77_RS13115	COG1970	mechanosensitive ion channel activity
EKH77_RS13135	COG0477	Major facilitator Superfamily
EKH77_RS13160	COG0514	ATP-dependent DNA helicase (RecQ)
EKH77_RS13215	COG1846	Transcriptional regulator
EKH77_RS13220	COG3384	dioxygenase
EKH77_RS13225	COG2207	Transcriptional regulator
EKH77_RS13225	COG3708	Transcriptional regulator
EKH77_RS13300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EKH77_RS13375	COG0515	serine threonine protein kinase
EKH77_RS13375	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EKH77_RS13385	COG1309	transcriptional regulator
EKH77_RS13395	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS13410	COG0045	succinate-CoA ligase (ADP-forming) activity
EKH77_RS13410	COG1042	CoA-binding domain protein
EKH77_RS13410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKH77_RS13415	COG1024	Enoyl-CoA hydratase
EKH77_RS13435	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS13440	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS13445	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS13460	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS13465	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS13475	COG1021	2,3-dihydroxybenzoate-AMP ligase
EKH77_RS13490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EKH77_RS13500	COG1077	Cell shape determining protein MreB Mrl
EKH77_RS13505	COG0516	GMP reductase activity
EKH77_RS13515	COG1595	DNA-templated transcription, initiation
EKH77_RS13520	COG2197	response regulator
EKH77_RS13530	COG0583	DNA-binding transcription factor activity
EKH77_RS13540	COG4221	oxidoreductase activity
EKH77_RS13555	COG0726	polysaccharide deacetylase
EKH77_RS13565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKH77_RS13590	COG0802	atpase or kinase
EKH77_RS13600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKH77_RS13610	COG0789	Transcriptional regulator
EKH77_RS13640	COG0736	holo-[acyl-carrier-protein] synthase activity
EKH77_RS13645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EKH77_RS13655	COG1072	(Pantothenic acid kinase))
EKH77_RS13660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKH77_RS13665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EKH77_RS13670	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EKH77_RS13675	COG0488	(ABC) transporter
EKH77_RS13695	COG0101	tRNA pseudouridine synthase activity
EKH77_RS13700	COG0203	ribosomal protein L17
EKH77_RS13710	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EKH77_RS13715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EKH77_RS13720	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EKH77_RS13725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKH77_RS13735	COG0563	adenylate kinase activity
EKH77_RS13745	COG0200	Binds to the 23S rRNA
EKH77_RS13755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EKH77_RS13760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EKH77_RS13765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EKH77_RS13770	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EKH77_RS13780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKH77_RS13785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EKH77_RS13790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EKH77_RS13795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EKH77_RS13800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EKH77_RS13805	COG0255	Belongs to the universal ribosomal protein uL29 family
EKH77_RS13810	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EKH77_RS13815	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EKH77_RS13820	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EKH77_RS13825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EKH77_RS13830	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EKH77_RS13835	COG0089	rRNA binding
EKH77_RS13840	COG0088	Forms part of the polypeptide exit tunnel
EKH77_RS13845	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EKH77_RS13850	COG0051	transcription antitermination factor activity, RNA binding
EKH77_RS13865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EKH77_RS13875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKH77_RS13880	COG0049	tRNA binding
EKH77_RS13885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EKH77_RS14025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKH77_RS14030	COG0085	RNA polymerase activity
EKH77_RS14045	COG0222	ribosome binding
EKH77_RS14055	COG0081	regulation of translation
EKH77_RS14065	COG0250	Participates in transcription elongation, termination and antitermination
EKH77_RS14080	COG0436	Aminotransferase
EKH77_RS14085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EKH77_RS14090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EKH77_RS14100	COG2030	dehydratase
EKH77_RS14105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EKH77_RS14125	COG0702	epimerase
EKH77_RS14135	COG1666	GTP binding
EKH77_RS14140	COG3304	Inner membrane component domain
EKH77_RS14155	COG0501	Belongs to the peptidase M48B family
EKH77_RS14160	COG1007	ATP synthesis coupled electron transport
EKH77_RS14170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EKH77_RS14175	COG0713	ATP synthesis coupled electron transport
EKH77_RS14180	COG0839	Belongs to the complex I subunit 6 family
EKH77_RS14185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKH77_RS14190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EKH77_RS14195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKH77_RS14205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKH77_RS14215	COG4585	Histidine kinase
EKH77_RS14225	COG0674	pyruvate-flavodoxin oxidoreductase activity
EKH77_RS14225	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EKH77_RS14230	COG1013	pyruvate-flavodoxin oxidoreductase activity
EKH77_RS14235	COG0531	amino acid
EKH77_RS14245	COG4935	Belongs to the peptidase S8 family
EKH77_RS14245	COG2234	aminopeptidase activity
EKH77_RS14265	COG0142	geranyltranstransferase activity
EKH77_RS14270	COG0492	ferredoxin-NADP+ reductase activity
EKH77_RS14295	COG1007	ATP synthesis coupled electron transport
EKH77_RS14305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EKH77_RS14310	COG0713	ATP synthesis coupled electron transport
EKH77_RS14315	COG0839	Belongs to the complex I subunit 6 family
EKH77_RS14320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKH77_RS14325	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EKH77_RS14330	COG1034	ATP synthesis coupled electron transport
EKH77_RS14335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EKH77_RS14345	COG0649	NAD binding
EKH77_RS14350	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKH77_RS14435	COG2226	methyltransferase
EKH77_RS14445	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EKH77_RS14450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EKH77_RS14450	COG0515	serine threonine protein kinase
EKH77_RS14455	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EKH77_RS14460	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EKH77_RS14465	COG1278	Cold shock
EKH77_RS14470	COG1022	Amp-dependent synthetase and ligase
EKH77_RS14500	COG1301	dicarboxylic acid transport
EKH77_RS14510	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EKH77_RS14520	COG0163	prenyltransferase activity
EKH77_RS14535	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EKH77_RS14550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EKH77_RS14555	COG1333	cytochrome c biogenesis protein
EKH77_RS14565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKH77_RS14575	COG0406	alpha-ribazole phosphatase activity
EKH77_RS14580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EKH77_RS14590	COG1742	UPF0060 membrane protein
EKH77_RS14610	COG1690	Belongs to the RtcB family
EKH77_RS14625	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EKH77_RS14630	COG0018	arginyl-trna synthetase
EKH77_RS14640	COG0113	porphobilinogen synthase activity
EKH77_RS14645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EKH77_RS14645	COG1648	precorrin-2 dehydrogenase activity
EKH77_RS14650	COG0181	hydroxymethylbilane synthase activity
EKH77_RS14655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EKH77_RS14660	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EKH77_RS14710	COG0123	including yeast histone deacetylase and acetoin utilization protein
EKH77_RS14735	COG0180	Tryptophanyl-tRNA synthetase
EKH77_RS14750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKH77_RS14780	COG1846	Transcriptional regulator
EKH77_RS14795	COG1252	NADH dehydrogenase
EKH77_RS14820	COG0579	oxidoreductase
EKH77_RS14830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EKH77_RS14880	COG3152	Membrane
EKH77_RS14900	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EKH77_RS14905	COG0667	Aldo Keto reductase
EKH77_RS14910	COG2814	Major facilitator Superfamily
EKH77_RS14930	COG1278	Cold shock
EKH77_RS14970	COG0432	Pfam Uncharacterised protein family UPF0047
EKH77_RS14980	COG0513	Belongs to the DEAD box helicase family
EKH77_RS15010	COG1643	Atp-dependent helicase
EKH77_RS15035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EKH77_RS15045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EKH77_RS15060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKH77_RS15065	COG0047	phosphoribosylformylglycinamidine synthase activity
EKH77_RS15070	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKH77_RS15110	COG4585	Histidine kinase
EKH77_RS15115	COG2197	response regulator
EKH77_RS15135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EKH77_RS15150	COG0151	Belongs to the GarS family
EKH77_RS15165	COG0463	Glycosyl transferase, family 2
EKH77_RS15170	COG1802	Transcriptional regulator
EKH77_RS15175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EKH77_RS15180	COG1278	Cold shock
EKH77_RS15185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EKH77_RS15185	COG0515	serine threonine protein kinase
EKH77_RS15220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EKH77_RS15230	COG2197	response regulator
EKH77_RS15235	COG4585	Histidine kinase
EKH77_RS15240	COG3844	kynureninase activity
EKH77_RS15245	COG3483	tryptophan 2,3-dioxygenase activity
EKH77_RS15255	COG0477	Major facilitator Superfamily
EKH77_RS15265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKH77_RS15290	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EKH77_RS15315	COG0542	response to heat
EKH77_RS15360	COG0789	Transcriptional regulator
EKH77_RS15365	COG0484	heat shock protein binding
EKH77_RS15370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EKH77_RS15375	COG0443	Heat shock 70 kDa protein
EKH77_RS15380	COG0247	lactate metabolic process
EKH77_RS15380	COG2181	nitrate reductase activity
EKH77_RS15400	COG0717	Belongs to the dCTP deaminase family
EKH77_RS15420	COG0640	Transcriptional regulator
EKH77_RS15425	COG0798	PFAM Bile acid sodium symporter
EKH77_RS15430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKH77_RS15435	COG3903	Transcriptional regulator
EKH77_RS15435	COG3629	intracellular signal transduction
EKH77_RS15440	COG2815	serine threonine protein kinase
EKH77_RS15440	COG0515	serine threonine protein kinase
EKH77_RS15520	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EKH77_RS15540	COG2205	protein histidine kinase activity
EKH77_RS15545	COG0745	RESPONSE REGULATOR receiver
EKH77_RS15565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKH77_RS15575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EKH77_RS15585	COG5634	Uncharacterized conserved protein (DUF2278)
EKH77_RS15590	COG1741	Belongs to the pirin family
EKH77_RS15605	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS15610	COG1362	aminopeptidase activity
EKH77_RS15635	COG2271	Major facilitator Superfamily
EKH77_RS15650	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKH77_RS15655	COG0022	dehydrogenase e1 component
EKH77_RS15680	COG0515	serine threonine protein kinase
EKH77_RS15685	COG0515	serine threonine protein kinase
EKH77_RS15700	COG0604	alcohol dehydrogenase
EKH77_RS15705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EKH77_RS15720	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKH77_RS15735	COG1522	sequence-specific DNA binding
EKH77_RS15740	COG1309	transcriptional regulator
EKH77_RS15745	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKH77_RS15770	COG3396	Phenylacetate-CoA oxygenase
EKH77_RS15775	COG3460	Phenylacetate-CoA oxygenase
EKH77_RS15780	COG3396	Phenylacetate-CoA oxygenase
EKH77_RS15785	COG2151	metal-sulfur cluster biosynthetic enzyme
EKH77_RS15790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EKH77_RS15800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKH77_RS15815	COG0442	prolyl-tRNA aminoacylation
EKH77_RS15825	COG1716	ATPase activity
EKH77_RS15830	COG1716	ATPase activity
EKH77_RS15845	COG0768	penicillin binding
EKH77_RS15850	COG0515	serine threonine protein kinase
EKH77_RS15855	COG3764	Sortase (surface protein transpeptidase)
EKH77_RS15875	COG3764	Sortase (surface protein transpeptidase)
EKH77_RS15890	COG0705	Rhomboid family
EKH77_RS15915	COG0515	serine threonine protein kinase
EKH77_RS15930	COG3266	domain, Protein
EKH77_RS15935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKH77_RS15945	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EKH77_RS15950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EKH77_RS15955	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EKH77_RS15960	COG0592	DNA-directed DNA polymerase activity
EKH77_RS15975	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EKH77_RS15985	COG0594	ribonuclease P activity
EKH77_RS15990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EKH77_RS15995	COG0706	membrane insertase activity
EKH77_RS16005	COG0357	Ribosomal RNA small subunit methyltransferase G
EKH77_RS16010	COG1192	Involved in chromosome partitioning
EKH77_RS16025	COG3118	belongs to the thioredoxin family
EKH77_RS16030	COG0492	ferredoxin-NADP+ reductase activity
EKH77_RS16040	COG1595	DNA-templated transcription, initiation
EKH77_RS16045	COG2815	serine threonine protein kinase
EKH77_RS16045	COG0515	serine threonine protein kinase
EKH77_RS16060	COG0617	tRNA 3'-terminal CCA addition
EKH77_RS16075	COG1260	myo-inositol-1-phosphate synthase
EKH77_RS16085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKH77_RS16110	COG0360	Binds together with S18 to 16S ribosomal RNA
EKH77_RS16115	COG0629	single-stranded DNA binding
EKH77_RS16120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EKH77_RS16125	COG0359	binds to the 23S rRNA
EKH77_RS16135	COG0305	Participates in initiation and elongation during chromosome replication
EKH77_RS16160	COG2814	Major facilitator Superfamily
EKH77_RS16185	COG1950	PFAM Membrane protein of
EKH77_RS16190	COG0662	Cupin 2, conserved barrel domain protein
EKH77_RS16205	COG2268	Band 7 protein
EKH77_RS16220	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EKH77_RS16235	COG1609	Transcriptional regulator
EKH77_RS16240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKH77_RS16245	COG1271	oxidase subunit
EKH77_RS16250	COG1294	oxidase, subunit
EKH77_RS16255	COG4988	ABC transporter
EKH77_RS16265	COG0739	heme binding
EKH77_RS16270	COG0561	phosphatase activity
EKH77_RS16280	COG0501	Belongs to the peptidase M48B family
EKH77_RS16300	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EKH77_RS16305	COG0789	Transcriptional regulator
EKH77_RS16325	COG1131	(ABC) transporter
EKH77_RS16345	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
EKH77_RS16350	COG2807	transmembrane transport
EKH77_RS16355	COG2188	Transcriptional regulator
EKH77_RS16365	COG0561	phosphatase activity
EKH77_RS16370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKH77_RS16380	COG2837	iron assimilation
EKH77_RS16385	COG2372	response to copper ion
EKH77_RS16420	COG0006	proline dipeptidase activity
EKH77_RS16440	COG0653	protein targeting
EKH77_RS16455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKH77_RS16500	COG0494	nUDIX hydrolase
EKH77_RS16505	COG0181	hydroxymethylbilane synthase activity
EKH77_RS16515	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EKH77_RS16520	COG2755	lipolytic protein G-D-S-L family
EKH77_RS16555	COG1595	DNA-templated transcription, initiation
EKH77_RS16575	COG0318	PFAM AMP-dependent synthetase and ligase
EKH77_RS16580	COG2814	Major facilitator Superfamily
EKH77_RS16585	COG1309	transcriptional regulator
EKH77_RS16590	COG0784	Response regulator, receiver
EKH77_RS16620	COG0745	RESPONSE REGULATOR receiver
EKH77_RS16625	COG0477	Major facilitator Superfamily
EKH77_RS16655	COG1191	sigma factor activity
EKH77_RS16660	COG1191	sigma factor activity
EKH77_RS16680	COG3629	intracellular signal transduction
EKH77_RS16680	COG3903	Transcriptional regulator
EKH77_RS16705	COG2409	Drug exporters of the RND superfamily
EKH77_RS16720	COG3903	Transcriptional regulator
EKH77_RS16720	COG3629	intracellular signal transduction
EKH77_RS16735	COG0318	PFAM AMP-dependent synthetase and ligase
EKH77_RS16740	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS16760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EKH77_RS16785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKH77_RS16800	COG1595	DNA-templated transcription, initiation
EKH77_RS16805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKH77_RS16810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKH77_RS16815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKH77_RS16815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKH77_RS16825	COG0590	tRNA wobble adenosine to inosine editing
EKH77_RS16840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EKH77_RS16865	COG2208	phosphoserine phosphatase activity
EKH77_RS16865	COG2770	Histidine kinase
EKH77_RS16895	COG4555	ABC transporter
EKH77_RS16915	COG1131	(ABC) transporter
EKH77_RS16960	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EKH77_RS16965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EKH77_RS17020	COG1595	DNA-templated transcription, initiation
EKH77_RS17180	COG1408	metallophosphoesterase
EKH77_RS17260	COG2267	carboxylic ester hydrolase activity
EKH77_RS17270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EKH77_RS17275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EKH77_RS17340	COG1205	dead DEAH box helicase
EKH77_RS17340	COG1111	helicase
EKH77_RS17345	COG1366	Belongs to the anti-sigma-factor antagonist family
EKH77_RS17355	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EKH77_RS17365	COG2890	protein-(glutamine-N5) methyltransferase activity
EKH77_RS17370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKH77_RS17370	COG1754	DNA topoisomerase type I activity
EKH77_RS17375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EKH77_RS17380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKH77_RS17470	COG2188	Transcriptional regulator
EKH77_RS17475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKH77_RS17490	COG2084	Dehydrogenase
EKH77_RS17500	COG3629	intracellular signal transduction
EKH77_RS17505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EKH77_RS17510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKH77_RS17565	COG1733	regulation of RNA biosynthetic process
EKH77_RS17585	COG1309	transcriptional regulator
EKH77_RS17595	COG4770	biotin carboxylase activity
EKH77_RS17620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKH77_RS17625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EKH77_RS17630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EKH77_RS17635	COG0254	rRNA binding
EKH77_RS17660	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS17665	COG2318	DinB family
EKH77_RS17705	COG0789	Transcriptional regulator
EKH77_RS17710	COG0393	Putative heavy-metal-binding
EKH77_RS17715	COG0586	Pfam SNARE associated Golgi protein
EKH77_RS17725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EKH77_RS17730	COG2027	D-alanyl-D-alanine carboxypeptidase
EKH77_RS17740	COG0037	tRNA processing
EKH77_RS17755	COG0302	gtp cyclohydrolase
EKH77_RS17765	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKH77_RS17765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EKH77_RS17780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EKH77_RS17785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EKH77_RS17795	COG1125	glycine betaine transport
EKH77_RS17795	COG0517	IMP dehydrogenase activity
EKH77_RS17800	COG1174	glycine betaine transport
EKH77_RS17805	COG1174	glycine betaine transport
EKH77_RS17820	COG0649	NAD binding
EKH77_RS17835	COG2197	response regulator
EKH77_RS17860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EKH77_RS17870	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EKH77_RS17895	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EKH77_RS17920	COG1280	lysine exporter protein (LysE YggA)
EKH77_RS17940	COG2205	protein histidine kinase activity
EKH77_RS17945	COG0745	RESPONSE REGULATOR receiver
EKH77_RS17955	COG1595	DNA-templated transcription, initiation
EKH77_RS17980	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EKH77_RS18000	COG0248	Ppx GppA phosphatase
EKH77_RS18005	COG1082	Xylose isomerase domain protein TIM barrel
EKH77_RS18010	COG1309	transcriptional regulator
EKH77_RS18015	COG0129	dihydroxy-acid dehydratase activity
EKH77_RS18020	COG0515	serine threonine protein kinase
EKH77_RS18020	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EKH77_RS18050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKH77_RS18055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EKH77_RS18090	COG0515	serine threonine protein kinase
EKH77_RS18090	COG2815	serine threonine protein kinase
EKH77_RS18165	COG0791	NLP P60 protein
EKH77_RS18170	COG0671	phosphoesterase, PA-phosphatase related
EKH77_RS18185	COG1937	Protein conserved in bacteria
EKH77_RS18195	COG0306	phosphate transporter
EKH77_RS18200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EKH77_RS18250	COG0590	tRNA wobble adenosine to inosine editing
EKH77_RS18265	COG0583	DNA-binding transcription factor activity
EKH77_RS18270	COG2890	protein-(glutamine-N5) methyltransferase activity
EKH77_RS18295	COG1490	D-aminoacyl-tRNA deacylase activity
EKH77_RS18305	COG4552	Acetyltransferase involved in intracellular survival and related
EKH77_RS18315	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS18325	COG0640	Transcriptional regulator
EKH77_RS18330	COG0477	Major facilitator Superfamily
EKH77_RS18345	COG4607	ABC-type enterochelin transport system periplasmic component
EKH77_RS18350	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EKH77_RS18355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKH77_RS18360	COG3485	protocatechuate 3,4-dioxygenase
EKH77_RS18380	COG2897	thiosulfate sulfurtransferase activity
EKH77_RS18420	COG0745	RESPONSE REGULATOR receiver
EKH77_RS18425	COG1609	Transcriptional regulator
EKH77_RS18430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKH77_RS18435	COG0745	RESPONSE REGULATOR receiver
EKH77_RS18440	COG2205	protein histidine kinase activity
EKH77_RS18495	COG0737	Belongs to the 5'-nucleotidase family
EKH77_RS18505	COG0456	acetyltransferase
EKH77_RS18510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EKH77_RS18530	COG2186	Transcriptional regulator
EKH77_RS18535	COG2807	transmembrane transport
EKH77_RS18540	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS18545	COG0477	Major facilitator Superfamily
EKH77_RS18560	COG0588	phosphoglycerate mutase activity
EKH77_RS18590	COG1329	Transcriptional regulator
EKH77_RS18595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EKH77_RS18600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EKH77_RS18605	COG3467	pyridoxamine 5'-phosphate
EKH77_RS18610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EKH77_RS18620	COG0215	cysteine-tRNA ligase activity
EKH77_RS18635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EKH77_RS18645	COG3842	ATPase activity
EKH77_RS18695	COG0789	Transcriptional regulator
EKH77_RS18700	COG1846	Transcriptional regulator
EKH77_RS18705	COG0697	spore germination
EKH77_RS18725	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EKH77_RS18730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKH77_RS18745	COG0191	fructose-bisphosphate aldolase activity
EKH77_RS18765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EKH77_RS18795	COG0463	Glycosyl transferase, family 2
EKH77_RS18810	COG1278	Cold shock
EKH77_RS18820	COG1061	Type III restriction enzyme res subunit
EKH77_RS18830	COG3973	AAA domain
EKH77_RS18835	COG3142	Participates in the control of copper homeostasis
EKH77_RS18845	COG2814	Major facilitator Superfamily
EKH77_RS18860	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EKH77_RS18865	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EKH77_RS18885	COG1120	ATPase activity
EKH77_RS18890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKH77_RS18895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKH77_RS18910	COG1278	Cold shock
EKH77_RS18915	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EKH77_RS18920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKH77_RS18930	COG2814	Major facilitator Superfamily
EKH77_RS18945	COG4195	phage-related replication protein
EKH77_RS18950	COG0515	serine threonine protein kinase
EKH77_RS19020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EKH77_RS19030	COG2252	PERMEase
EKH77_RS19040	COG2814	Major facilitator Superfamily
EKH77_RS19055	COG0701	Predicted permease
EKH77_RS19060	COG0667	Aldo Keto reductase
EKH77_RS19090	COG0596	Alpha beta hydrolase
EKH77_RS19095	COG1309	transcriptional regulator
EKH77_RS19110	COG1309	transcriptional regulator
EKH77_RS19130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EKH77_RS19140	COG0277	FAD linked oxidase domain protein
EKH77_RS19140	COG0247	lactate metabolic process
EKH77_RS19145	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EKH77_RS19170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EKH77_RS19175	COG2945	thiolester hydrolase activity
EKH77_RS19175	COG0596	Alpha beta hydrolase
EKH77_RS19185	COG4821	SIS domain
EKH77_RS19195	COG0259	pyridoxamine-phosphate oxidase activity
EKH77_RS19210	COG1131	(ABC) transporter
EKH77_RS19255	COG4585	Histidine kinase
EKH77_RS19260	COG2197	response regulator
EKH77_RS19320	COG0515	serine threonine protein kinase
EKH77_RS19320	COG2815	serine threonine protein kinase
EKH77_RS19325	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS19340	COG0519	Catalyzes the synthesis of GMP from XMP
EKH77_RS19340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EKH77_RS19360	COG1376	ErfK ybiS ycfS ynhG family protein
EKH77_RS19380	COG0515	serine threonine protein kinase
EKH77_RS19390	COG2197	response regulator
EKH77_RS19415	COG0739	heme binding
EKH77_RS19425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKH77_RS19440	COG0714	Associated with various cellular activities
EKH77_RS19450	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EKH77_RS19455	COG0045	succinate-CoA ligase (ADP-forming) activity
EKH77_RS19480	COG0138	bifunctional purine biosynthesis protein purh
EKH77_RS19485	COG1714	RDD family
EKH77_RS19490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EKH77_RS19500	COG0538	isocitrate dehydrogenase activity
EKH77_RS19525	COG0039	L-malate dehydrogenase activity
EKH77_RS19545	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS19555	COG4175	Glycine betaine
EKH77_RS19555	COG0517	IMP dehydrogenase activity
EKH77_RS19560	COG4176	ABC-type proline glycine betaine transport system permease component
EKH77_RS19580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKH77_RS19585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKH77_RS19645	COG0754	glutathionylspermidine amidase activity
EKH77_RS19650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EKH77_RS19660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EKH77_RS19665	COG0180	Tryptophanyl-tRNA synthetase
EKH77_RS19675	COG1295	ribonuclease BN
EKH77_RS19680	COG1686	Belongs to the peptidase S11 family
EKH77_RS19715	COG1053	succinate dehydrogenase
EKH77_RS19725	COG2009	succinate dehydrogenase
EKH77_RS19740	COG1595	DNA-templated transcription, initiation
EKH77_RS19750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKH77_RS19750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKH77_RS19785	COG2186	Transcriptional regulator
EKH77_RS19790	COG3265	gluconokinase activity
EKH77_RS19840	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EKH77_RS19850	COG1216	Glycosyl transferase, family 2
EKH77_RS19865	COG2089	acid synthase
EKH77_RS19875	COG1473	amidohydrolase
EKH77_RS19875	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EKH77_RS19880	COG1744	ABC transporter substrate-binding protein PnrA-like
EKH77_RS19890	COG4603	Belongs to the binding-protein-dependent transport system permease family
EKH77_RS19895	COG1079	Belongs to the binding-protein-dependent transport system permease family
EKH77_RS19910	COG2824	Alkylphosphonate utilization operon protein PhnA
EKH77_RS19935	COG2814	Major facilitator Superfamily
EKH77_RS19940	COG0583	DNA-binding transcription factor activity
EKH77_RS19950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EKH77_RS19975	COG2205	protein histidine kinase activity
EKH77_RS19980	COG0745	RESPONSE REGULATOR receiver
EKH77_RS20000	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS20005	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS20010	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EKH77_RS20030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKH77_RS20060	COG4770	biotin carboxylase activity
EKH77_RS20075	COG0424	maF-like protein
EKH77_RS20080	COG0768	penicillin binding
EKH77_RS20090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EKH77_RS20100	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EKH77_RS20105	COG1024	Enoyl-CoA hydratase
EKH77_RS20115	COG2986	histidine ammonia-lyase
EKH77_RS20125	COG1376	ErfK ybiS ycfS ynhG family protein
EKH77_RS20145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EKH77_RS20175	COG2226	methyltransferase
EKH77_RS20175	COG2867	negative regulation of translational initiation
EKH77_RS20180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKH77_RS20215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EKH77_RS20230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EKH77_RS20240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EKH77_RS20250	COG1331	Highly conserved protein containing a thioredoxin domain
EKH77_RS20270	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EKH77_RS20320	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EKH77_RS20335	COG1414	Transcriptional regulator
EKH77_RS20340	COG0251	oxidation-reduction process
EKH77_RS20410	COG2885	chlorophyll binding
EKH77_RS20455	COG2345	Transcriptional regulator
EKH77_RS20485	COG2132	Multicopper oxidase
EKH77_RS20490	COG1309	transcriptional regulator
EKH77_RS20495	COG2814	Major facilitator Superfamily
EKH77_RS20500	COG0667	Aldo Keto reductase
EKH77_RS20505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKH77_RS20510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EKH77_RS20525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKH77_RS20530	COG0450	alkyl hydroperoxide reductase
EKH77_RS20545	COG1136	(ABC) transporter
EKH77_RS20575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKH77_RS20600	COG0114	fumarate hydratase activity
EKH77_RS20605	COG2755	lipolytic protein G-D-S-L family
EKH77_RS20610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EKH77_RS20610	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EKH77_RS20635	COG0778	Nitroreductase
EKH77_RS20640	COG1722	exodeoxyribonuclease VII activity
EKH77_RS20645	COG1570	exodeoxyribonuclease VII activity
EKH77_RS20655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EKH77_RS20670	COG0012	GTP binding
EKH77_RS20675	COG2161	toxin-antitoxin pair type II binding
EKH77_RS20680	COG4115	mRNA cleavage
EKH77_RS20705	COG0531	amino acid
EKH77_RS20760	COG1217	gtp-binding protein TYPA
EKH77_RS20775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKH77_RS20780	COG0444	Belongs to the ABC transporter superfamily
EKH77_RS20785	COG4608	Belongs to the ABC transporter superfamily
EKH77_RS20795	COG1280	lysine exporter protein (LysE YggA)
EKH77_RS20800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EKH77_RS20845	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS20855	COG0601	transmembrane transport
EKH77_RS20860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKH77_RS20870	COG4608	Belongs to the ABC transporter superfamily
EKH77_RS20880	COG4608	Belongs to the ABC transporter superfamily
EKH77_RS20885	COG0444	Belongs to the ABC transporter superfamily
EKH77_RS20895	COG4166	transmembrane transport
EKH77_RS20900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKH77_RS20915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EKH77_RS20940	COG1131	(ABC) transporter
EKH77_RS20950	COG4585	Histidine kinase
EKH77_RS20955	COG2197	response regulator
EKH77_RS20990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EKH77_RS21000	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EKH77_RS21010	COG0519	Catalyzes the synthesis of GMP from XMP
EKH77_RS21015	COG1024	Enoyl-CoA hydratase
EKH77_RS21030	COG1595	DNA-templated transcription, initiation
EKH77_RS21040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKH77_RS21045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKH77_RS21055	COG3422	double-strand break repair
EKH77_RS21090	COG0598	Magnesium transport protein CorA
EKH77_RS21110	COG2095	MarC family integral membrane protein
EKH77_RS21125	COG0513	Belongs to the DEAD box helicase family
EKH77_RS21170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKH77_RS21255	COG0210	DNA helicase
EKH77_RS21260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EKH77_RS21340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EKH77_RS21390	COG3480	Lon protease (S16) C-terminal proteolytic domain
EKH77_RS21400	COG1615	UPF0182 protein
EKH77_RS21425	COG0753	catalase activity
EKH77_RS21435	COG0483	inositol monophosphate 1-phosphatase activity
EKH77_RS21445	COG2076	Multidrug Resistance protein
EKH77_RS21455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EKH77_RS21465	COG2135	peptidase activity
EKH77_RS21475	COG1595	DNA-templated transcription, initiation
EKH77_RS21480	COG5662	AntiSigma factor
EKH77_RS21485	COG2199	diguanylate cyclase activity
EKH77_RS21485	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EKH77_RS21500	COG0242	peptide deformylase activity
EKH77_RS21505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKH77_RS21530	COG0659	secondary active sulfate transmembrane transporter activity
EKH77_RS21580	COG2188	Transcriptional regulator
EKH77_RS21585	COG2182	Extracellular solute-binding protein
EKH77_RS21590	COG1175	transmembrane transport
EKH77_RS21595	COG0395	ABC-type sugar transport system, permease component
EKH77_RS21600	COG1472	Belongs to the glycosyl hydrolase 3 family
EKH77_RS21605	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EKH77_RS21610	COG0363	glucosamine-6-phosphate deaminase activity
EKH77_RS21625	COG1597	lipid kinase activity
EKH77_RS21665	COG2066	Belongs to the glutaminase family
EKH77_RS21675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKH77_RS21700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EKH77_RS21705	COG0640	Transcriptional regulator
EKH77_RS21730	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EKH77_RS21755	COG0765	amino acid transport
EKH77_RS21765	COG0281	malic enzyme
EKH77_RS21815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKH77_RS21820	COG0567	Dehydrogenase, E1 component
EKH77_RS21820	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKH77_RS21825	COG2205	protein histidine kinase activity
EKH77_RS21830	COG0745	RESPONSE REGULATOR receiver
EKH77_RS21845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EKH77_RS21910	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EKH77_RS21970	COG1116	anion transmembrane transporter activity
EKH77_RS21975	COG1309	transcriptional regulator
EKH77_RS22050	COG1660	Displays ATPase and GTPase activities
EKH77_RS22150	COG0745	RESPONSE REGULATOR receiver
EKH77_RS22155	COG0018	arginyl-trna synthetase
EKH77_RS22160	COG0019	diaminopimelate decarboxylase activity
EKH77_RS22165	COG0460	homoserine dehydrogenase
EKH77_RS22170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EKH77_RS22175	COG0083	homoserine kinase activity
EKH77_RS22190	COG0254	rRNA binding
EKH77_RS22195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EKH77_RS22200	COG2890	protein-(glutamine-N5) methyltransferase activity
EKH77_RS22210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKH77_RS22215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EKH77_RS22220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKH77_RS22235	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKH77_RS22240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKH77_RS22245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKH77_RS22250	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKH77_RS22255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EKH77_RS22260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EKH77_RS22265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EKH77_RS22280	COG4585	Histidine kinase
EKH77_RS22285	COG2197	response regulator
EKH77_RS22310	COG1309	transcriptional regulator
EKH77_RS22315	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKH77_RS22330	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EKH77_RS22370	COG1131	(ABC) transporter
EKH77_RS22390	COG0183	Belongs to the thiolase family
EKH77_RS22400	COG1846	Transcriptional regulator
EKH77_RS22460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKH77_RS22460	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKH77_RS22500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EKH77_RS22505	COG0857	belongs to the CobB CobQ family
EKH77_RS22505	COG0280	phosphate acetyltransferase
EKH77_RS22510	COG0205	6-phosphofructokinase activity
EKH77_RS22515	COG0577	efflux transmembrane transporter activity
EKH77_RS22515	COG1136	(ABC) transporter
EKH77_RS22520	COG1136	(ABC) transporter
EKH77_RS22535	COG3833	ABC-type maltose transport systems, permease component
EKH77_RS22560	COG1175	transmembrane transport
EKH77_RS22570	COG4565	transcriptional regulatory protein
EKH77_RS22575	COG3290	protein histidine kinase activity
EKH77_RS22580	COG1301	dicarboxylic acid transport
EKH77_RS22620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EKH77_RS22625	COG3281	Trehalose synthase
EKH77_RS22635	COG0366	Alpha amylase catalytic
EKH77_RS22640	COG0058	SHG alpha-glucan phosphorylase activity
EKH77_RS22650	COG1132	(ABC) transporter
EKH77_RS22665	COG1376	ErfK ybiS ycfS ynhG family protein
EKH77_RS22675	COG1024	Enoyl-CoA hydratase
EKH77_RS22700	COG1324	tolerance protein
EKH77_RS22710	COG2207	Transcriptional regulator
EKH77_RS22715	COG0346	lactoylglutathione lyase activity
EKH77_RS22720	COG0477	Major facilitator Superfamily
EKH77_RS22725	COG0346	lactoylglutathione lyase activity
EKH77_RS22730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EKH77_RS22780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EKH77_RS22785	COG1733	regulation of RNA biosynthetic process
EKH77_RS22790	COG4221	oxidoreductase activity
EKH77_RS22845	COG2188	Transcriptional regulator
EKH77_RS22875	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EKH77_RS22905	COG1760	l-serine dehydratase
EKH77_RS22910	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EKH77_RS22915	COG0509	glycine decarboxylation via glycine cleavage system
EKH77_RS22920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EKH77_RS22945	COG4166	transmembrane transport
EKH77_RS22955	COG0444	Belongs to the ABC transporter superfamily
EKH77_RS22960	COG4608	Belongs to the ABC transporter superfamily
EKH77_RS22970	COG2860	membrane
EKH77_RS22980	COG2378	regulation of single-species biofilm formation
EKH77_RS22990	COG0482	sulfurtransferase activity
EKH77_RS23020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EKH77_RS23030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKH77_RS23035	COG0154	amidase activity
EKH77_RS23045	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKH77_RS23055	COG2409	Drug exporters of the RND superfamily
EKH77_RS23060	COG2133	pyrroloquinoline quinone binding
EKH77_RS23065	COG0667	Aldo Keto reductase
EKH77_RS23095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EKH77_RS23100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EKH77_RS23105	COG2188	Transcriptional regulator
EKH77_RS23110	COG0477	Major facilitator Superfamily
EKH77_RS23120	COG2124	cytochrome p450
EKH77_RS23130	COG3835	regulator
EKH77_RS23135	COG0506	proline dehydrogenase activity
EKH77_RS23140	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS23150	COG0473	3-isopropylmalate dehydrogenase activity
EKH77_RS23155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EKH77_RS23160	COG0477	Major facilitator Superfamily
EKH77_RS23165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKH77_RS23180	COG2353	YceI-like domain
EKH77_RS23185	COG5492	domain, Protein
EKH77_RS23190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EKH77_RS23210	COG2018	Roadblock/LC7 domain
EKH77_RS23230	COG2018	Roadblock/LC7 domain
EKH77_RS23235	COG5002	protein histidine kinase activity
EKH77_RS23245	COG0179	Fumarylacetoacetate (FAA) hydrolase
EKH77_RS23250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKH77_RS23295	COG1414	Transcriptional regulator
EKH77_RS23300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKH77_RS23305	COG0066	3-isopropylmalate dehydratase activity
EKH77_RS23315	COG0776	regulation of translation
EKH77_RS23330	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EKH77_RS23335	COG1181	Belongs to the D-alanine--D-alanine ligase family
EKH77_RS23355	COG0351	phosphomethylpyrimidine kinase
EKH77_RS23360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EKH77_RS23365	COG1461	Dihydroxyacetone kinase
EKH77_RS23375	COG0742	ribosomal rna small subunit methyltransferase
EKH77_RS23380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EKH77_RS23395	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EKH77_RS23400	COG0571	ribonuclease III activity
EKH77_RS23405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EKH77_RS23410	COG1733	regulation of RNA biosynthetic process
EKH77_RS23425	COG1254	Belongs to the acylphosphatase family
EKH77_RS23440	COG1196	nuclear chromosome segregation
EKH77_RS23445	COG0477	Major facilitator Superfamily
EKH77_RS23450	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EKH77_RS23480	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EKH77_RS23495	COG0442	prolyl-tRNA aminoacylation
EKH77_RS23505	COG0228	four-way junction DNA binding
EKH77_RS23510	COG1837	Belongs to the UPF0109 family
EKH77_RS23515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EKH77_RS23520	COG0336	Belongs to the RNA methyltransferase TrmD family
EKH77_RS23525	COG0335	large ribosomal subunit rRNA binding
EKH77_RS23530	COG0681	Belongs to the peptidase S26 family
EKH77_RS23560	COG0792	nuclease activity
EKH77_RS23575	COG1191	sigma factor activity
EKH77_RS23590	COG0052	Belongs to the universal ribosomal protein uS2 family
EKH77_RS23595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EKH77_RS23600	COG0528	UMP kinase activity
EKH77_RS23605	COG0233	cytoplasmic translational termination
EKH77_RS23615	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EKH77_RS23630	COG3842	ATPase activity
EKH77_RS23655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EKH77_RS23665	COG1012	belongs to the aldehyde dehydrogenase family
EKH77_RS23680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EKH77_RS23695	COG3842	ATPase activity
EKH77_RS23700	COG1176	ABC-type spermidine putrescine transport system, permease component I
EKH77_RS23705	COG1177	transmembrane transport
EKH77_RS23710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKH77_RS23745	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EKH77_RS23750	COG0750	zinc metalloprotease
EKH77_RS23755	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EKH77_RS23770	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
EKH77_RS23785	COG0779	Required for maturation of 30S ribosomal subunits
EKH77_RS23800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EKH77_RS23810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EKH77_RS23815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EKH77_RS23830	COG0455	bacterial-type flagellum organization
EKH77_RS23850	COG1404	Belongs to the peptidase S8 family
EKH77_RS23890	COG1404	Belongs to the peptidase S8 family
EKH77_RS23940	COG1674	ftsk spoiiie
EKH77_RS23950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EKH77_RS23955	COG1185	polyribonucleotide nucleotidyltransferase activity
EKH77_RS23960	COG0612	Peptidase, M16
EKH77_RS23965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EKH77_RS23985	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EKH77_RS23990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKH77_RS23995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKH77_RS24030	COG2208	phosphoserine phosphatase activity
EKH77_RS24030	COG2770	Histidine kinase
EKH77_RS24035	COG3437	response regulator, receiver
EKH77_RS24035	COG2205	protein histidine kinase activity
EKH77_RS24035	COG3850	Histidine kinase
EKH77_RS24035	COG4999	Histidine kinase
EKH77_RS24055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKH77_RS24065	COG1546	Belongs to the CinA family
EKH77_RS24065	COG1058	Belongs to the CinA family
EKH77_RS24070	COG1396	sequence-specific DNA binding
EKH77_RS24075	COG0783	Belongs to the Dps family
EKH77_RS24085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EKH77_RS24090	COG1201	RNA secondary structure unwinding
EKH77_RS24105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EKH77_RS24115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKH77_RS24130	COG0765	amino acid transport
EKH77_RS24135	COG0765	amino acid transport
EKH77_RS24140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EKH77_RS24145	COG1126	abc transporter atp-binding protein
EKH77_RS24150	COG0745	RESPONSE REGULATOR receiver
EKH77_RS24155	COG2205	protein histidine kinase activity
EKH77_RS24165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKH77_RS24185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EKH77_RS24195	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EKH77_RS24200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKH77_RS24210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKH77_RS24240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKH77_RS24245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EKH77_RS24250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKH77_RS24265	COG0588	phosphoglycerate mutase activity
EKH77_RS24275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKH77_RS24310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKH77_RS24315	COG1802	Transcriptional regulator
EKH77_RS24320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKH77_RS24335	COG0187	DNA topoisomerase II activity
EKH77_RS24340	COG4585	Histidine kinase
EKH77_RS24345	COG2197	response regulator
EKH77_RS24350	COG4565	transcriptional regulatory protein
EKH77_RS24355	COG3290	protein histidine kinase activity
EKH77_RS24365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EKH77_RS24385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKH77_RS24390	COG0612	Peptidase, M16
EKH77_RS24405	COG1802	Transcriptional regulator
EKH77_RS24410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKH77_RS24430	COG1435	thymidine kinase activity
EKH77_RS24465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EKH77_RS24470	COG0483	inositol monophosphate 1-phosphatase activity
EKH77_RS24475	COG0745	RESPONSE REGULATOR receiver
EKH77_RS24480	COG2205	protein histidine kinase activity
EKH77_RS24505	COG0756	dUTP diphosphatase activity
EKH77_RS24520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EKH77_RS24525	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EKH77_RS24530	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EKH77_RS24570	COG0569	domain protein
EKH77_RS24600	COG2124	cytochrome p450
EKH77_RS24605	COG0531	amino acid
EKH77_RS24610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKH77_RS24645	COG2226	methyltransferase
EKH77_RS24655	COG1799	cell septum assembly
EKH77_RS24680	COG2040	homocysteine
EKH77_RS24690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EKH77_RS24695	COG2235	arginine
EKH77_RS24700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKH77_RS24705	COG1024	Enoyl-CoA hydratase
EKH77_RS24725	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS24745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKH77_RS24760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EKH77_RS24810	COG1653	transport
EKH77_RS24815	COG1175	transmembrane transport
EKH77_RS24820	COG0395	ABC-type sugar transport system, permease component
EKH77_RS24825	COG1940	carbohydrate kinase activity
EKH77_RS24830	COG4213	ABC transporter substrate-binding protein
EKH77_RS24840	COG4214	carbohydrate transport
EKH77_RS24845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKH77_RS24850	COG0531	amino acid
EKH77_RS24895	COG1024	Enoyl-CoA hydratase
EKH77_RS24895	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKH77_RS24900	COG0183	Belongs to the thiolase family
EKH77_RS24920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EKH77_RS24930	COG3485	protocatechuate 3,4-dioxygenase
EKH77_RS24935	COG0183	Belongs to the thiolase family
EKH77_RS24940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EKH77_RS24945	COG3253	May function as heme-dependent peroxidase
EKH77_RS24975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKH77_RS24995	COG1278	Cold shock
EKH77_RS25005	COG0583	DNA-binding transcription factor activity
EKH77_RS25010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKH77_RS25040	COG1136	(ABC) transporter
EKH77_RS25040	COG0577	efflux transmembrane transporter activity
EKH77_RS25045	COG0577	efflux transmembrane transporter activity
EKH77_RS25050	COG4585	Histidine kinase
EKH77_RS25055	COG2197	response regulator
EKH77_RS25060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EKH77_RS25065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKH77_RS25095	COG5002	protein histidine kinase activity
EKH77_RS25095	COG2176	DNA-directed DNA polymerase activity
EKH77_RS25150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EKH77_RS25155	COG1116	anion transmembrane transporter activity
EKH77_RS25180	COG0529	Catalyzes the synthesis of activated sulfate
EKH77_RS25185	COG0175	sulfate reduction
EKH77_RS25215	COG1162	GTPase activity
EKH77_RS25220	COG1802	Transcriptional regulator
EKH77_RS25245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKH77_RS25255	COG4264	IucA IucC family
EKH77_RS25285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EKH77_RS25290	COG2252	PERMEase
EKH77_RS25340	COG1285	pathogenesis
EKH77_RS25345	COG0135	phosphoribosylanthranilate isomerase activity
EKH77_RS25350	COG0019	diaminopimelate decarboxylase activity
EKH77_RS25355	COG0259	pyridoxamine-phosphate oxidase activity
EKH77_RS25375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EKH77_RS25380	COG0134	indole-3-glycerol-phosphate synthase activity
EKH77_RS25385	COG1280	lysine exporter protein (LysE YggA)
EKH77_RS25445	COG3226	Transcriptional regulator
EKH77_RS25465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EKH77_RS25470	COG0318	PFAM AMP-dependent synthetase and ligase
EKH77_RS25480	COG3960	tartronate-semialdehyde synthase activity
EKH77_RS25485	COG2084	Dehydrogenase
EKH77_RS25490	COG3622	Belongs to the hyi family
EKH77_RS25510	COG2351	hydroxyisourate hydrolase activity
EKH77_RS25525	COG2233	PERMEase
EKH77_RS25530	COG1288	antiporter activity
EKH77_RS25535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EKH77_RS25540	COG2068	MobA-Related Protein
EKH77_RS25550	COG1414	Transcriptional regulator
EKH77_RS25555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EKH77_RS25560	COG4266	Belongs to the allantoicase family
EKH77_RS25600	COG2188	Transcriptional regulator
EKH77_RS25605	COG1879	ABC-type sugar transport system periplasmic component
EKH77_RS25610	COG1172	Belongs to the binding-protein-dependent transport system permease family
EKH77_RS25620	COG1940	carbohydrate kinase activity
EKH77_RS25645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKH77_RS25675	COG1126	abc transporter atp-binding protein
EKH77_RS25680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EKH77_RS25685	COG0765	amino acid transport
EKH77_RS25690	COG0765	amino acid transport
EKH77_RS25695	COG2255	four-way junction helicase activity
EKH77_RS25705	COG1959	2 iron, 2 sulfur cluster binding
EKH77_RS25720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EKH77_RS25725	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS25735	COG0367	asparagine synthase
EKH77_RS25760	COG1045	serine acetyltransferase
EKH77_RS25805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EKH77_RS25810	COG0019	diaminopimelate decarboxylase activity
EKH77_RS25825	COG4166	transmembrane transport
EKH77_RS25830	COG0601	transmembrane transport
EKH77_RS25850	COG0405	Gamma-glutamyltransferase
EKH77_RS25865	COG1335	isochorismatase
EKH77_RS25880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EKH77_RS25905	COG0483	inositol monophosphate 1-phosphatase activity
EKH77_RS25915	COG4221	oxidoreductase activity
EKH77_RS25945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKH77_RS25950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EKH77_RS25955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EKH77_RS25960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKH77_RS25965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKH77_RS25975	COG1929	Belongs to the glycerate kinase type-1 family
EKH77_RS25985	COG0688	phosphatidylethanolamine metabolic process
EKH77_RS25990	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS26000	COG2301	Belongs to the HpcH HpaI aldolase family
EKH77_RS26005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKH77_RS26005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKH77_RS26070	COG1120	ATPase activity
EKH77_RS26075	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS26080	COG1169	isochorismate synthase
EKH77_RS26085	COG1021	2,3-dihydroxybenzoate-AMP ligase
EKH77_RS26090	COG1535	isochorismatase
EKH77_RS26090	COG3433	isochorismatase activity
EKH77_RS26095	COG1535	isochorismatase
EKH77_RS26095	COG3433	isochorismatase activity
EKH77_RS26100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EKH77_RS26155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EKH77_RS26165	COG0531	amino acid
EKH77_RS26175	COG1309	transcriptional regulator
EKH77_RS26190	COG2154	pterin-4-alpha-carbinolamine dehydratase
EKH77_RS26195	COG0656	L-ascorbic acid biosynthetic process
EKH77_RS26205	COG0583	DNA-binding transcription factor activity
EKH77_RS26235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EKH77_RS26255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EKH77_RS26270	COG1100	Small GTP-binding protein
EKH77_RS26310	COG0477	Major facilitator Superfamily
EKH77_RS26340	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EKH77_RS26365	COG1515	deoxyribonuclease V activity
EKH77_RS26390	COG2272	Belongs to the type-B carboxylesterase lipase family
EKH77_RS26395	COG2936	dipeptidyl-peptidase activity
EKH77_RS26410	COG1024	Enoyl-CoA hydratase
EKH77_RS26410	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKH77_RS26415	COG0183	Belongs to the thiolase family
EKH77_RS26420	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS26425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EKH77_RS26435	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS26445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EKH77_RS26470	COG0488	(ABC) transporter
EKH77_RS26485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKH77_RS26495	COG0318	PFAM AMP-dependent synthetase and ligase
EKH77_RS26500	COG2197	response regulator
EKH77_RS26505	COG4585	Histidine kinase
EKH77_RS26510	COG1131	(ABC) transporter
EKH77_RS26520	COG2183	response to ionizing radiation
EKH77_RS26530	COG4977	sequence-specific DNA binding
EKH77_RS26540	COG1024	Enoyl-CoA hydratase
EKH77_RS26550	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EKH77_RS26580	COG0371	Dehydrogenase
EKH77_RS26600	COG1134	teichoic acid transport
EKH77_RS26605	COG1562	ergosterol biosynthetic process
EKH77_RS26615	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EKH77_RS26625	COG1657	PFAM Prenyltransferase squalene oxidase
EKH77_RS26635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EKH77_RS26640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EKH77_RS26645	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKH77_RS26665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKH77_RS26690	COG2755	lipolytic protein G-D-S-L family
EKH77_RS26700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EKH77_RS26755	COG1228	amidohydrolase
EKH77_RS26890	COG4974	Belongs to the 'phage' integrase family
EKH77_RS26940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKH77_RS26945	COG0640	Transcriptional regulator
EKH77_RS27000	COG2124	cytochrome p450
EKH77_RS27055	COG0515	serine threonine protein kinase
EKH77_RS27120	COG1846	Transcriptional regulator
EKH77_RS27160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EKH77_RS27170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EKH77_RS27185	COG0488	(ABC) transporter
EKH77_RS27210	COG0477	Major facilitator Superfamily
EKH77_RS27220	COG0789	Transcriptional regulator
EKH77_RS27225	COG1819	glycosyl
EKH77_RS27240	COG1132	(ABC) transporter
EKH77_RS27255	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EKH77_RS27275	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EKH77_RS27280	COG5285	phytanoyl-CoA dioxygenase
EKH77_RS27285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EKH77_RS27345	COG1733	regulation of RNA biosynthetic process
EKH77_RS27350	COG0477	Major facilitator Superfamily
EKH77_RS27355	COG0460	homoserine dehydrogenase
EKH77_RS27380	COG2873	o-acetylhomoserine
EKH77_RS27395	COG2838	Isocitrate dehydrogenase
EKH77_RS27405	COG3290	protein histidine kinase activity
EKH77_RS27420	COG0583	DNA-binding transcription factor activity
EKH77_RS27480	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EKH77_RS27505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKH77_RS27515	COG1172	Belongs to the binding-protein-dependent transport system permease family
EKH77_RS27520	COG1129	ABC transporter
EKH77_RS27525	COG1609	Transcriptional regulator
EKH77_RS27560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKH77_RS27565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKH77_RS27615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EKH77_RS27680	COG0531	amino acid
EKH77_RS27685	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EKH77_RS27695	COG5002	protein histidine kinase activity
EKH77_RS27700	COG0745	RESPONSE REGULATOR receiver
EKH77_RS27715	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EKH77_RS27725	COG0531	amino acid
EKH77_RS27730	COG3537	Alpha-1,2-mannosidase
EKH77_RS27775	COG0204	Acyl-transferase
EKH77_RS27790	COG1335	isochorismatase
EKH77_RS27815	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EKH77_RS27820	COG0121	glutamine amidotransferase
EKH77_RS27825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EKH77_RS27860	COG1024	Enoyl-CoA hydratase
EKH77_RS27865	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS27875	COG0745	RESPONSE REGULATOR receiver
EKH77_RS27880	COG2205	protein histidine kinase activity
EKH77_RS27900	COG1846	Transcriptional regulator
EKH77_RS27910	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS27915	COG1960	acyl-CoA dehydrogenase activity
EKH77_RS27920	COG1024	Enoyl-CoA hydratase
EKH77_RS27930	COG1309	transcriptional regulator
EKH77_RS27935	COG0183	Belongs to the thiolase family
EKH77_RS27945	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EKH77_RS27950	COG1687	branched-chain amino acid
EKH77_RS27975	COG1024	Enoyl-CoA hydratase
EKH77_RS27985	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS28010	COG1124	(ABC) transporter
EKH77_RS28020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKH77_RS28040	COG4249	Peptidase C14 caspase catalytic subunit p20
EKH77_RS28040	COG2319	Wd-40 repeat
EKH77_RS28085	COG1609	Transcriptional regulator
EKH77_RS28095	COG1175	transmembrane transport
EKH77_RS28100	COG0395	ABC-type sugar transport system, permease component
EKH77_RS28120	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKH77_RS28120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EKH77_RS28155	COG2867	negative regulation of translational initiation
EKH77_RS28165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKH77_RS28170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKH77_RS28205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKH77_RS28210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKH77_RS28240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EKH77_RS28260	COG3511	phospholipase C
EKH77_RS28270	COG2018	Roadblock/LC7 domain
EKH77_RS28290	COG1132	(ABC) transporter
EKH77_RS28295	COG1132	(ABC) transporter
EKH77_RS28310	COG1132	(ABC) transporter
EKH77_RS28325	COG1556	Lactate utilization protein
EKH77_RS28330	COG1139	Iron-sulfur cluster binding protein
EKH77_RS28335	COG0247	lactate metabolic process
EKH77_RS28340	COG0492	ferredoxin-NADP+ reductase activity
EKH77_RS28345	COG0432	Pfam Uncharacterised protein family UPF0047
EKH77_RS28370	COG2706	6-phosphogluconolactonase activity
EKH77_RS28385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKH77_RS28400	COG1309	transcriptional regulator
EKH77_RS28415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKH77_RS28435	COG4106	trans-aconitate 2-methyltransferase activity
EKH77_RS28450	COG0463	Glycosyl transferase, family 2
EKH77_RS28455	COG0438	transferase activity, transferring glycosyl groups
EKH77_RS28460	COG0297	glycogen (starch) synthase activity
EKH77_RS28490	COG0596	Alpha beta hydrolase
EKH77_RS28515	COG1832	CoA-binding protein
EKH77_RS28520	COG1739	Uncharacterized protein family UPF0029
EKH77_RS28530	COG0419	ATPase involved in DNA repair
EKH77_RS28535	COG1522	sequence-specific DNA binding
EKH77_RS28555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKH77_RS28570	COG1595	DNA-templated transcription, initiation
EKH77_RS28575	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS28580	COG2188	Transcriptional regulator
EKH77_RS28585	COG1940	carbohydrate kinase activity
EKH77_RS28590	COG3663	DNA glycosylase
EKH77_RS28595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EKH77_RS28620	COG2226	methyltransferase
EKH77_RS28625	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EKH77_RS28645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EKH77_RS28650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EKH77_RS28655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EKH77_RS28690	COG0740	serine-type endopeptidase activity
EKH77_RS28700	COG0831	urea catabolic process
EKH77_RS28705	COG0832	Belongs to the urease beta subunit family
EKH77_RS28710	COG0804	urea catabolic process
EKH77_RS28715	COG0830	nickel cation binding
EKH77_RS28720	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EKH77_RS28725	COG0829	nickel cation binding
EKH77_RS28750	COG0251	oxidation-reduction process
EKH77_RS28770	COG3336	cytochrome c oxidase
EKH77_RS28775	COG0205	6-phosphofructokinase activity
EKH77_RS28790	COG0242	peptide deformylase activity
EKH77_RS28870	COG1819	glycosyl
EKH77_RS28920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKH77_RS28935	COG3251	PFAM MbtH domain protein
EKH77_RS28940	COG0477	Major facilitator Superfamily
EKH77_RS28945	COG2382	esterase
EKH77_RS28950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKH77_RS28955	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS29005	COG2329	Antibiotic biosynthesis monooxygenase
EKH77_RS29025	COG3629	intracellular signal transduction
EKH77_RS29025	COG3903	Transcriptional regulator
EKH77_RS29040	COG1064	alcohol dehydrogenase
EKH77_RS29045	COG2409	Drug exporters of the RND superfamily
EKH77_RS29050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKH77_RS29065	COG1970	mechanosensitive ion channel activity
EKH77_RS29070	COG4585	Histidine kinase
EKH77_RS29075	COG2197	response regulator
EKH77_RS29130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKH77_RS29180	COG1181	Belongs to the D-alanine--D-alanine ligase family
EKH77_RS29185	COG1181	Belongs to the D-alanine--D-alanine ligase family
EKH77_RS29195	COG2226	methyltransferase
EKH77_RS29210	COG0702	epimerase
EKH77_RS29215	COG1733	regulation of RNA biosynthetic process
EKH77_RS29225	COG2409	Drug exporters of the RND superfamily
EKH77_RS29245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EKH77_RS29275	COG2072	flavoprotein involved in K transport
EKH77_RS29285	COG2826	transposase and inactivated derivatives, IS30 family
EKH77_RS29310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKH77_RS29355	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EKH77_RS29410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKH77_RS29420	COG4106	trans-aconitate 2-methyltransferase activity
EKH77_RS29435	COG0028	Belongs to the TPP enzyme family
EKH77_RS29445	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EKH77_RS29465	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EKH77_RS29510	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EKH77_RS29510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EKH77_RS29515	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EKH77_RS29520	COG0297	glycogen (starch) synthase activity
EKH77_RS29535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EKH77_RS29545	COG2192	nodulation
EKH77_RS29550	COG1088	dTDP-glucose 4,6-dehydratase activity
EKH77_RS29575	COG1573	uracil-dna glycosylase
EKH77_RS29590	COG0693	protein deglycase activity
EKH77_RS29605	COG3237	CsbD-like
EKH77_RS29610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKH77_RS29620	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EKH77_RS29645	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EKH77_RS29650	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EKH77_RS29675	COG0298	carbon dioxide binding
EKH77_RS29680	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EKH77_RS29685	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EKH77_RS29690	COG0375	protein maturation
EKH77_RS29695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EKH77_RS29720	COG1006	Multisubunit Na H antiporter MnhC subunit
EKH77_RS29725	COG1007	ATP synthesis coupled electron transport
EKH77_RS29765	COG2936	dipeptidyl-peptidase activity
EKH77_RS29770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKH77_RS29805	COG3387	PFAM Glycoside hydrolase 15-related
EKH77_RS29835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKH77_RS29845	COG0318	PFAM AMP-dependent synthetase and ligase
EKH77_RS29860	COG2813	Specifically methylates the guanine in position
EKH77_RS29880	COG1309	transcriptional regulator
EKH77_RS29890	COG1231	oxidoreductase activity
EKH77_RS29900	COG2124	cytochrome p450
EKH77_RS29905	COG0110	maltose O-acetyltransferase activity
EKH77_RS29935	COG5635	Nacht domain
EKH77_RS29935	COG2319	Wd-40 repeat
EKH77_RS29950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EKH77_RS29955	COG3321	synthase
EKH77_RS29955	COG0604	alcohol dehydrogenase
EKH77_RS29955	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS29970	COG2267	carboxylic ester hydrolase activity
EKH77_RS29995	COG1113	amino acid transport
EKH77_RS30000	COG3511	phospholipase C
EKH77_RS30010	COG2175	clavaminate synthase activity
EKH77_RS30025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKH77_RS30070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKH77_RS30075	COG1215	transferase activity, transferring glycosyl groups
EKH77_RS30120	COG4608	Belongs to the ABC transporter superfamily
EKH77_RS30130	COG0601	transmembrane transport
EKH77_RS30135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKH77_RS30145	COG0006	proline dipeptidase activity
EKH77_RS30150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKH77_RS30170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKH77_RS30175	COG3938	Belongs to the proline racemase family
EKH77_RS30185	COG1802	Transcriptional regulator
EKH77_RS30275	COG0513	Belongs to the DEAD box helicase family
EKH77_RS30330	COG1073	alpha beta
EKH77_RS30455	COG2326	polyphosphate kinase activity
EKH77_RS30460	COG4191	Histidine kinase
EKH77_RS30525	COG4221	oxidoreductase activity
EKH77_RS30665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EKH77_RS30735	COG0142	geranyltranstransferase activity
EKH77_RS30740	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EKH77_RS30755	COG2197	response regulator
EKH77_RS30760	COG3851	Histidine kinase
EKH77_RS30805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKH77_RS30875	COG1280	lysine exporter protein (LysE YggA)
EKH77_RS30960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKH77_RS31000	COG2226	methyltransferase
EKH77_RS31025	COG2205	protein histidine kinase activity
EKH77_RS31030	COG0745	RESPONSE REGULATOR receiver
EKH77_RS31075	COG1942	4-Oxalocrotonate Tautomerase
EKH77_RS31110	COG0739	heme binding
EKH77_RS31185	COG0789	Transcriptional regulator
EKH77_RS31195	COG0477	Major facilitator Superfamily
EKH77_RS31215	COG1733	regulation of RNA biosynthetic process
EKH77_RS31220	COG3293	Transposase
EKH77_RS31250	COG0702	epimerase
EKH77_RS31290	COG0110	maltose O-acetyltransferase activity
EKH77_RS31295	COG1309	transcriptional regulator
EKH77_RS31310	COG0673	inositol 2-dehydrogenase activity
EKH77_RS31325	COG1819	glycosyl
EKH77_RS31340	COG0300	oxidoreductase activity
EKH77_RS31385	COG0523	cobalamin synthesis protein
EKH77_RS31405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKH77_RS31445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EKH77_RS31465	COG4221	oxidoreductase activity
EKH77_RS31505	COG2815	serine threonine protein kinase
EKH77_RS31505	COG0515	serine threonine protein kinase
EKH77_RS31515	COG0076	glutamate decarboxylase activity
EKH77_RS31530	COG4552	Acetyltransferase involved in intracellular survival and related
EKH77_RS31555	COG3321	synthase
EKH77_RS31555	COG0604	alcohol dehydrogenase
EKH77_RS31560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EKH77_RS31565	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS31570	COG1946	Acyl-CoA thioesterase
EKH77_RS31575	COG2409	Drug exporters of the RND superfamily
EKH77_RS31595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKH77_RS31660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKH77_RS31670	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS31670	COG0604	alcohol dehydrogenase
EKH77_RS31670	COG3321	synthase
EKH77_RS31680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKH77_RS31710	COG3387	PFAM Glycoside hydrolase 15-related
EKH77_RS31725	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS31735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKH77_RS31750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKH77_RS31765	COG0604	alcohol dehydrogenase
EKH77_RS31765	COG3321	synthase
EKH77_RS31820	COG1172	Belongs to the binding-protein-dependent transport system permease family
EKH77_RS31825	COG1129	ABC transporter
EKH77_RS31845	COG0628	permease
EKH77_RS31890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EKH77_RS31915	COG0367	asparagine synthase
EKH77_RS31970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKH77_RS31980	COG0028	Belongs to the TPP enzyme family
EKH77_RS31990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKH77_RS32020	COG2124	cytochrome p450
EKH77_RS32040	COG2208	phosphoserine phosphatase activity
EKH77_RS32065	COG0531	amino acid
EKH77_RS32090	COG1309	transcriptional regulator
EKH77_RS32105	COG0723	plastoquinol--plastocyanin reductase activity
EKH77_RS32105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKH77_RS32130	COG0535	radical SAM domain protein
EKH77_RS32135	COG0515	serine threonine protein kinase
EKH77_RS32140	COG3152	Membrane
EKH77_RS32145	COG0142	geranyltranstransferase activity
EKH77_RS32150	COG0586	Pfam SNARE associated Golgi protein
EKH77_RS32160	COG0531	amino acid
EKH77_RS32175	COG3619	membrane
EKH77_RS32185	COG0668	transmembrane transport
EKH77_RS32210	COG1595	DNA-templated transcription, initiation
EKH77_RS32235	COG1902	pentaerythritol trinitrate reductase activity
EKH77_RS32260	COG2226	methyltransferase
EKH77_RS32270	COG0346	lactoylglutathione lyase activity
EKH77_RS32275	COG4221	oxidoreductase activity
EKH77_RS32325	COG2814	Major facilitator Superfamily
EKH77_RS32330	COG1063	alcohol dehydrogenase
EKH77_RS32340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKH77_RS32370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EKH77_RS32370	COG2124	cytochrome p450
EKH77_RS32390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EKH77_RS32400	COG2124	cytochrome p450
EKH77_RS32415	COG1028	Short-chain dehydrogenase reductase Sdr
EKH77_RS32505	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKH77_RS32600	COG2205	protein histidine kinase activity
EKH77_RS32615	COG2175	clavaminate synthase activity
EKH77_RS32630	COG1335	isochorismatase
EKH77_RS32650	COG1090	epimerase
EKH77_RS32670	COG2197	response regulator
EKH77_RS32680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKH77_RS32685	COG0574	Belongs to the PEP-utilizing enzyme family
EKH77_RS32685	COG3848	Pyruvate phosphate dikinase
EKH77_RS32695	COG3547	Transposase (IS116 IS110 IS902 family)
EKH77_RS32700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase