locus-tag	class	description
NCG97_RS00040	COG0667	Aldo Keto reductase
NCG97_RS00070	COG3293	Transposase
NCG97_RS00075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NCG97_RS00120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NCG97_RS00275	COG3293	Transposase
NCG97_RS00360	COG2319	Wd-40 repeat
NCG97_RS00360	COG4249	Peptidase C14 caspase catalytic subunit p20
NCG97_RS00395	COG1660	Displays ATPase and GTPase activities
NCG97_RS00400	COG2319	Wd-40 repeat
NCG97_RS00400	COG4249	Peptidase C14 caspase catalytic subunit p20
NCG97_RS00495	COG2391	methyltransferase activity
NCG97_RS00500	COG0515	serine threonine protein kinase
NCG97_RS00580	COG1169	isochorismate synthase
NCG97_RS00855	COG0672	)-iron permease
NCG97_RS00895	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NCG97_RS00910	COG0577	efflux transmembrane transporter activity
NCG97_RS00915	COG1136	(ABC) transporter
NCG97_RS00920	COG2197	response regulator
NCG97_RS00925	COG4585	Histidine kinase
NCG97_RS00945	COG0201	protein transport
NCG97_RS01010	COG0300	oxidoreductase activity
NCG97_RS01030	COG3226	Transcriptional regulator
NCG97_RS01055	COG2318	DinB family
NCG97_RS01075	COG2197	response regulator
NCG97_RS01075	COG3903	Transcriptional regulator
NCG97_RS01105	COG0832	Belongs to the urease beta subunit family
NCG97_RS01110	COG0804	urea catabolic process
NCG97_RS01115	COG0830	nickel cation binding
NCG97_RS01120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NCG97_RS01125	COG0829	nickel cation binding
NCG97_RS01135	COG1113	amino acid transport
NCG97_RS01145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NCG97_RS01150	COG0509	glycine decarboxylation via glycine cleavage system
NCG97_RS01155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NCG97_RS01205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NCG97_RS01235	COG3118	belongs to the thioredoxin family
NCG97_RS01245	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NCG97_RS01260	COG1846	Transcriptional regulator
NCG97_RS01265	COG2271	Major facilitator Superfamily
NCG97_RS01280	COG3293	Transposase
NCG97_RS01290	COG1309	transcriptional regulator
NCG97_RS01320	COG1309	transcriptional regulator
NCG97_RS01350	COG0367	asparagine synthase
NCG97_RS01355	COG2814	Major facilitator Superfamily
NCG97_RS01365	COG1120	ATPase activity
NCG97_RS01415	COG2205	protein histidine kinase activity
NCG97_RS01435	COG2124	cytochrome p450
NCG97_RS01510	COG1752	Esterase of the alpha-beta hydrolase superfamily
NCG97_RS01515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NCG97_RS01525	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NCG97_RS01595	COG2226	methyltransferase
NCG97_RS01615	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NCG97_RS01645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NCG97_RS01685	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NCG97_RS01685	COG1672	PFAM Archaeal ATPase
NCG97_RS01690	COG3629	intracellular signal transduction
NCG97_RS01715	COG1802	Transcriptional regulator
NCG97_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS01725	COG3938	Belongs to the proline racemase family
NCG97_RS01770	COG3979	chitinase
NCG97_RS01800	COG4585	Histidine kinase
NCG97_RS01835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCG97_RS01835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCG97_RS01840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NCG97_RS01860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NCG97_RS01905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NCG97_RS02015	COG1191	sigma factor activity
NCG97_RS02025	COG2208	phosphoserine phosphatase activity
NCG97_RS02025	COG2770	Histidine kinase
NCG97_RS02060	COG0583	DNA-binding transcription factor activity
NCG97_RS02065	COG0531	amino acid
NCG97_RS02070	COG0583	DNA-binding transcription factor activity
NCG97_RS02080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NCG97_RS02095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NCG97_RS02155	COG1959	2 iron, 2 sulfur cluster binding
NCG97_RS02160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NCG97_RS02160	COG1017	nitric oxide dioxygenase activity
NCG97_RS02175	COG2252	PERMEase
NCG97_RS02210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NCG97_RS02210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NCG97_RS02250	COG0431	NADPH-dependent FMN reductase
NCG97_RS02255	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NCG97_RS02260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NCG97_RS02270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NCG97_RS02335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NCG97_RS02335	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NCG97_RS02355	COG0142	geranyltranstransferase activity
NCG97_RS02360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NCG97_RS02365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NCG97_RS02370	COG0477	Major facilitator Superfamily
NCG97_RS02390	COG0477	Major facilitator Superfamily
NCG97_RS02405	COG4585	Histidine kinase
NCG97_RS02410	COG2197	response regulator
NCG97_RS02450	COG0328	RNA-DNA hybrid ribonuclease activity
NCG97_RS02460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NCG97_RS02465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NCG97_RS02470	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NCG97_RS02475	COG0110	maltose O-acetyltransferase activity
NCG97_RS02550	COG2197	response regulator
NCG97_RS02555	COG0151	Belongs to the GarS family
NCG97_RS02610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS02610	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NCG97_RS02640	COG4221	oxidoreductase activity
NCG97_RS02675	COG1652	LysM domain
NCG97_RS02685	COG0339	signal peptide processing
NCG97_RS02700	COG0583	DNA-binding transcription factor activity
NCG97_RS02715	COG1846	Transcriptional regulator
NCG97_RS02740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NCG97_RS02745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NCG97_RS02785	COG3227	Zinc metalloprotease (Elastase)
NCG97_RS02795	COG2124	cytochrome p450
NCG97_RS02825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NCG97_RS02830	COG3395	kinase activity
NCG97_RS02840	COG1349	DNA-binding transcription factor activity
NCG97_RS02870	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS02885	COG1793	dna ligase
NCG97_RS02900	COG0531	amino acid
NCG97_RS02910	COG2837	iron assimilation
NCG97_RS02925	COG0298	carbon dioxide binding
NCG97_RS02930	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NCG97_RS02935	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NCG97_RS02940	COG0375	protein maturation
NCG97_RS02970	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NCG97_RS02990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NCG97_RS03000	COG0477	Major facilitator Superfamily
NCG97_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS03025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NCG97_RS03055	COG3960	tartronate-semialdehyde synthase activity
NCG97_RS03060	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS03080	COG3442	glutamine amidotransferase
NCG97_RS03085	COG0205	6-phosphofructokinase activity
NCG97_RS03155	COG0829	nickel cation binding
NCG97_RS03160	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NCG97_RS03165	COG0830	nickel cation binding
NCG97_RS03170	COG0804	urea catabolic process
NCG97_RS03175	COG0832	Belongs to the urease beta subunit family
NCG97_RS03180	COG0831	urea catabolic process
NCG97_RS03195	COG0740	serine-type endopeptidase activity
NCG97_RS03230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NCG97_RS03240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NCG97_RS03245	COG2226	methyltransferase
NCG97_RS03265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NCG97_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS03310	COG0456	acetyltransferase
NCG97_RS03330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NCG97_RS03340	COG3511	phospholipase C
NCG97_RS03360	COG1940	carbohydrate kinase activity
NCG97_RS03365	COG2188	Transcriptional regulator
NCG97_RS03375	COG1595	DNA-templated transcription, initiation
NCG97_RS03400	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS03410	COG0420	3'-5' exonuclease activity
NCG97_RS03415	COG1739	Uncharacterized protein family UPF0029
NCG97_RS03445	COG0110	maltose O-acetyltransferase activity
NCG97_RS03535	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NCG97_RS03550	COG1968	undecaprenyl-diphosphatase activity
NCG97_RS03590	COG2770	Histidine kinase
NCG97_RS03590	COG2208	phosphoserine phosphatase activity
NCG97_RS03610	COG1940	carbohydrate kinase activity
NCG97_RS03620	COG1175	transmembrane transport
NCG97_RS03625	COG0395	ABC-type sugar transport system, permease component
NCG97_RS03635	COG1764	response to oxidative stress
NCG97_RS03640	COG1846	Transcriptional regulator
NCG97_RS03690	COG0739	heme binding
NCG97_RS03700	COG1609	Transcriptional regulator
NCG97_RS03710	COG1175	transmembrane transport
NCG97_RS03715	COG0395	ABC-type sugar transport system, permease component
NCG97_RS03750	COG1278	Cold shock
NCG97_RS03760	COG2356	endonuclease I
NCG97_RS03765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NCG97_RS03775	COG3285	dna ligase
NCG97_RS03775	COG1793	dna ligase
NCG97_RS03790	COG3012	SEC-C Motif Domain Protein
NCG97_RS03835	COG1216	Glycosyl transferase, family 2
NCG97_RS03845	COG1228	amidohydrolase
NCG97_RS03875	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS03890	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS03905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NCG97_RS03935	COG0584	glycerophosphoryl diester phosphodiesterase
NCG97_RS03965	COG0069	glutamate synthase activity
NCG97_RS03980	COG0596	Alpha beta hydrolase
NCG97_RS03990	COG0640	Transcriptional regulator
NCG97_RS04020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NCG97_RS04035	COG2124	cytochrome p450
NCG97_RS04050	COG0531	amino acid
NCG97_RS04085	COG0504	CTP synthase activity
NCG97_RS04180	COG1231	oxidoreductase activity
NCG97_RS04185	COG3961	Belongs to the TPP enzyme family
NCG97_RS04195	COG2205	protein histidine kinase activity
NCG97_RS04275	COG1609	Transcriptional regulator
NCG97_RS04280	COG1957	nucleoside hydrolase
NCG97_RS04285	COG0477	Major facilitator Superfamily
NCG97_RS04310	COG1335	isochorismatase
NCG97_RS04320	COG0243	molybdopterin cofactor binding
NCG97_RS04320	COG3383	formate dehydrogenase (NAD+) activity
NCG97_RS04325	COG0437	4 iron, 4 sulfur cluster binding
NCG97_RS04335	COG1252	NADH dehydrogenase
NCG97_RS04360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NCG97_RS04370	COG1113	amino acid transport
NCG97_RS04390	COG0604	alcohol dehydrogenase
NCG97_RS04395	COG1309	transcriptional regulator
NCG97_RS04425	COG1902	pentaerythritol trinitrate reductase activity
NCG97_RS04435	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NCG97_RS04465	COG2706	6-phosphogluconolactonase activity
NCG97_RS04480	COG4213	ABC transporter substrate-binding protein
NCG97_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS04500	COG1304	FMN binding
NCG97_RS04505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCG97_RS04510	COG2271	Major facilitator Superfamily
NCG97_RS04525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NCG97_RS04550	COG1254	Belongs to the acylphosphatase family
NCG97_RS04620	COG3291	Pkd domain containing protein
NCG97_RS04645	COG1473	amidohydrolase
NCG97_RS04665	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NCG97_RS04670	COG2197	response regulator
NCG97_RS04710	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NCG97_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS04740	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS04775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NCG97_RS04790	COG2814	Major facilitator Superfamily
NCG97_RS04800	COG3629	intracellular signal transduction
NCG97_RS04875	COG0492	ferredoxin-NADP+ reductase activity
NCG97_RS04910	COG0432	Pfam Uncharacterised protein family UPF0047
NCG97_RS04915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NCG97_RS04920	COG1116	anion transmembrane transporter activity
NCG97_RS04930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS04935	COG2072	flavoprotein involved in K transport
NCG97_RS04950	COG2018	Roadblock/LC7 domain
NCG97_RS04965	COG0477	Major facilitator Superfamily
NCG97_RS05005	COG0242	peptide deformylase activity
NCG97_RS05015	COG1132	(ABC) transporter
NCG97_RS05045	COG1132	(ABC) transporter
NCG97_RS05050	COG1132	(ABC) transporter
NCG97_RS05060	COG3973	AAA domain
NCG97_RS05065	COG4552	Acetyltransferase involved in intracellular survival and related
NCG97_RS05080	COG1946	Acyl-CoA thioesterase
NCG97_RS05090	COG2018	Roadblock/LC7 domain
NCG97_RS05105	COG4106	trans-aconitate 2-methyltransferase activity
NCG97_RS05145	COG2040	homocysteine
NCG97_RS05150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NCG97_RS05155	COG0765	amino acid transport
NCG97_RS05175	COG3458	cephalosporin-C deacetylase activity
NCG97_RS05185	COG1070	Carbohydrate kinase
NCG97_RS05195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCG97_RS05200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCG97_RS05200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCG97_RS05230	COG3511	phospholipase C
NCG97_RS05250	COG0596	Alpha beta hydrolase
NCG97_RS05305	COG0588	phosphoglycerate mutase activity
NCG97_RS05310	COG1070	Carbohydrate kinase
NCG97_RS05320	COG2814	Major facilitator Superfamily
NCG97_RS05330	COG0667	Aldo Keto reductase
NCG97_RS05340	COG4221	oxidoreductase activity
NCG97_RS05405	COG1388	LysM domain
NCG97_RS05405	COG3858	chitin binding
NCG97_RS05430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NCG97_RS05440	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NCG97_RS05480	COG3360	Dodecin
NCG97_RS05500	COG0583	DNA-binding transcription factor activity
NCG97_RS05510	COG3537	Alpha-1,2-mannosidase
NCG97_RS05580	COG2133	pyrroloquinoline quinone binding
NCG97_RS05580	COG5183	chlorophyll binding
NCG97_RS05610	COG1113	amino acid transport
NCG97_RS05615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NCG97_RS05635	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS05690	COG0174	glutamine synthetase
NCG97_RS05705	COG3246	L-lysine catabolic process to acetate
NCG97_RS05710	COG1250	3-hydroxyacyl-CoA dehydrogenase
NCG97_RS05750	COG1686	Belongs to the peptidase S11 family
NCG97_RS05755	COG2124	cytochrome p450
NCG97_RS05800	COG3958	Transketolase
NCG97_RS05805	COG2267	carboxylic ester hydrolase activity
NCG97_RS05815	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS05835	COG2018	Roadblock/LC7 domain
NCG97_RS05855	COG2267	carboxylic ester hydrolase activity
NCG97_RS05870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCG97_RS05895	COG2755	lipolytic protein G-D-S-L family
NCG97_RS05900	COG2365	Tyrosine phosphatase family
NCG97_RS05925	COG1657	PFAM Prenyltransferase squalene oxidase
NCG97_RS05935	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NCG97_RS05950	COG1134	teichoic acid transport
NCG97_RS05985	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NCG97_RS06025	COG2183	response to ionizing radiation
NCG97_RS06065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NCG97_RS06075	COG2936	dipeptidyl-peptidase activity
NCG97_RS06100	COG3568	Endonuclease Exonuclease Phosphatase
NCG97_RS06105	COG2197	response regulator
NCG97_RS06125	COG1113	amino acid transport
NCG97_RS06140	COG0183	Belongs to the thiolase family
NCG97_RS06145	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS06150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NCG97_RS06165	COG3268	Saccharopine dehydrogenase
NCG97_RS06170	COG1515	deoxyribonuclease V activity
NCG97_RS06185	COG2814	Major facilitator Superfamily
NCG97_RS06190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NCG97_RS06200	COG1349	DNA-binding transcription factor activity
NCG97_RS06210	COG1309	transcriptional regulator
NCG97_RS06220	COG1309	transcriptional regulator
NCG97_RS06230	COG1846	Transcriptional regulator
NCG97_RS06275	COG0745	RESPONSE REGULATOR receiver
NCG97_RS06280	COG2205	protein histidine kinase activity
NCG97_RS06325	COG0583	DNA-binding transcription factor activity
NCG97_RS06350	COG1309	transcriptional regulator
NCG97_RS06380	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS06405	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS06410	COG0287	Prephenate dehydrogenase
NCG97_RS06410	COG1605	Chorismate mutase
NCG97_RS06430	COG0604	alcohol dehydrogenase
NCG97_RS06460	COG0656	L-ascorbic acid biosynthetic process
NCG97_RS06470	COG4106	trans-aconitate 2-methyltransferase activity
NCG97_RS06485	COG1295	ribonuclease BN
NCG97_RS06490	COG2154	pterin-4-alpha-carbinolamine dehydratase
NCG97_RS06525	COG0531	amino acid
NCG97_RS06535	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NCG97_RS06555	COG0454	-acetyltransferase
NCG97_RS06555	COG0456	acetyltransferase
NCG97_RS06585	COG2207	Transcriptional regulator
NCG97_RS06590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NCG97_RS06600	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS06610	COG0010	Belongs to the arginase family
NCG97_RS06640	COG2124	cytochrome p450
NCG97_RS06655	COG1619	proteins homologs of microcin C7 resistance protein MccF
NCG97_RS06660	COG4946	Tricorn protease homolog
NCG97_RS06660	COG0823	Involved in the tonB-independent uptake of proteins
NCG97_RS06660	COG1506	peptidase
NCG97_RS06665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NCG97_RS06670	COG2362	D-Aminopeptidase
NCG97_RS06695	COG0596	Alpha beta hydrolase
NCG97_RS06700	COG2814	Major facilitator Superfamily
NCG97_RS06740	COG1250	3-hydroxyacyl-CoA dehydrogenase
NCG97_RS06760	COG2301	Belongs to the HpcH HpaI aldolase family
NCG97_RS06770	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS06775	COG0688	phosphatidylethanolamine metabolic process
NCG97_RS06785	COG1929	Belongs to the glycerate kinase type-1 family
NCG97_RS06840	COG0483	inositol monophosphate 1-phosphatase activity
NCG97_RS06860	COG1953	Uracil, thiamine, allantoin
NCG97_RS06865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS06870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NCG97_RS06880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NCG97_RS06900	COG0405	Gamma-glutamyltransferase
NCG97_RS06920	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS06930	COG2409	Drug exporters of the RND superfamily
NCG97_RS06940	COG0435	Glutathione S-transferase
NCG97_RS06950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NCG97_RS06955	COG0596	Alpha beta hydrolase
NCG97_RS06965	COG0765	amino acid transport
NCG97_RS06970	COG0765	amino acid transport
NCG97_RS06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NCG97_RS06980	COG1126	abc transporter atp-binding protein
NCG97_RS07000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NCG97_RS07005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NCG97_RS07075	COG0159	tryptophan synthase activity
NCG97_RS07170	COG4585	Histidine kinase
NCG97_RS07180	COG1136	(ABC) transporter
NCG97_RS07185	COG0577	efflux transmembrane transporter activity
NCG97_RS07220	COG0745	RESPONSE REGULATOR receiver
NCG97_RS07225	COG2205	protein histidine kinase activity
NCG97_RS07295	COG2197	response regulator
NCG97_RS07350	COG1595	DNA-templated transcription, initiation
NCG97_RS07535	COG3693	PFAM glycoside hydrolase, family 10
NCG97_RS07710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS07715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS07740	COG0765	amino acid transport
NCG97_RS07755	COG1733	regulation of RNA biosynthetic process
NCG97_RS07765	COG0784	Response regulator, receiver
NCG97_RS07765	COG5002	protein histidine kinase activity
NCG97_RS07765	COG2205	protein histidine kinase activity
NCG97_RS07805	COG0477	Major facilitator Superfamily
NCG97_RS07820	COG0574	Belongs to the PEP-utilizing enzyme family
NCG97_RS07820	COG3848	Pyruvate phosphate dikinase
NCG97_RS07835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NCG97_RS07870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NCG97_RS07880	COG0789	Transcriptional regulator
NCG97_RS07915	COG1172	Belongs to the binding-protein-dependent transport system permease family
NCG97_RS07930	COG2188	Transcriptional regulator
NCG97_RS07950	COG0800	Aldolase
NCG97_RS07985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NCG97_RS07990	COG1953	Uracil, thiamine, allantoin
NCG97_RS08000	COG1414	Transcriptional regulator
NCG97_RS08025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NCG97_RS08055	COG0174	glutamine synthetase
NCG97_RS08065	COG1473	amidohydrolase
NCG97_RS08070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NCG97_RS08090	COG2233	PERMEase
NCG97_RS08110	COG2351	hydroxyisourate hydrolase activity
NCG97_RS08130	COG3622	Belongs to the hyi family
NCG97_RS08135	COG2084	Dehydrogenase
NCG97_RS08140	COG0753	catalase activity
NCG97_RS08165	COG2315	Protein conserved in bacteria
NCG97_RS08170	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS08175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NCG97_RS08190	COG0583	DNA-binding transcription factor activity
NCG97_RS08195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NCG97_RS08200	COG2318	DinB family
NCG97_RS08205	COG4552	Acetyltransferase involved in intracellular survival and related
NCG97_RS08210	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NCG97_RS08210	COG3608	succinylglutamate desuccinylase aspartoacylase
NCG97_RS08215	COG2252	PERMEase
NCG97_RS08220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NCG97_RS08250	COG1802	Transcriptional regulator
NCG97_RS08275	COG0460	homoserine dehydrogenase
NCG97_RS08280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS08310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS08335	COG0667	Aldo Keto reductase
NCG97_RS08360	COG1162	GTPase activity
NCG97_RS08400	COG0028	Belongs to the TPP enzyme family
NCG97_RS08420	COG1162	GTPase activity
NCG97_RS08425	COG2318	DinB family
NCG97_RS08430	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS08450	COG1073	alpha beta
NCG97_RS08455	COG1073	alpha beta
NCG97_RS08490	COG2755	lipolytic protein G-D-S-L family
NCG97_RS08490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NCG97_RS08495	COG1215	transferase activity, transferring glycosyl groups
NCG97_RS08510	COG0842	Transport permease protein
NCG97_RS08510	COG1131	(ABC) transporter
NCG97_RS08510	COG1716	ATPase activity
NCG97_RS08535	COG1376	ErfK ybiS ycfS ynhG family protein
NCG97_RS08545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NCG97_RS08550	COG3511	phospholipase C
NCG97_RS08555	COG4106	trans-aconitate 2-methyltransferase activity
NCG97_RS08565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NCG97_RS08585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NCG97_RS08590	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NCG97_RS08625	COG1309	transcriptional regulator
NCG97_RS08665	COG2208	phosphoserine phosphatase activity
NCG97_RS08665	COG2770	Histidine kinase
NCG97_RS08675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NCG97_RS08685	COG3485	protocatechuate 3,4-dioxygenase
NCG97_RS08690	COG3485	protocatechuate 3,4-dioxygenase
NCG97_RS08695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NCG97_RS08715	COG2814	Major facilitator Superfamily
NCG97_RS08725	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS08740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS08755	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NCG97_RS08765	COG0175	sulfate reduction
NCG97_RS08770	COG0529	Catalyzes the synthesis of activated sulfate
NCG97_RS08785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NCG97_RS08790	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NCG97_RS08795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NCG97_RS08805	COG0366	Alpha amylase catalytic
NCG97_RS08825	COG1609	Transcriptional regulator
NCG97_RS08830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NCG97_RS08860	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS08865	COG0583	DNA-binding transcription factor activity
NCG97_RS08885	COG0583	DNA-binding transcription factor activity
NCG97_RS08925	COG1511	domain protein
NCG97_RS08955	COG1063	alcohol dehydrogenase
NCG97_RS08965	COG1136	(ABC) transporter
NCG97_RS08965	COG0577	efflux transmembrane transporter activity
NCG97_RS08970	COG1136	(ABC) transporter
NCG97_RS08975	COG2197	response regulator
NCG97_RS09020	COG2318	DinB family
NCG97_RS09030	COG0477	Major facilitator Superfamily
NCG97_RS09070	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS09110	COG0583	DNA-binding transcription factor activity
NCG97_RS09130	COG0693	protein deglycase activity
NCG97_RS09140	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NCG97_RS09165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NCG97_RS09170	COG2197	response regulator
NCG97_RS09185	COG1136	(ABC) transporter
NCG97_RS09245	COG3253	May function as heme-dependent peroxidase
NCG97_RS09250	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NCG97_RS09255	COG0183	Belongs to the thiolase family
NCG97_RS09260	COG0446	pyridine nucleotide-disulphide oxidoreductase
NCG97_RS09300	COG0183	Belongs to the thiolase family
NCG97_RS09305	COG1250	3-hydroxyacyl-CoA dehydrogenase
NCG97_RS09305	COG1024	Enoyl-CoA hydratase
NCG97_RS09315	COG0531	amino acid
NCG97_RS09320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NCG97_RS09325	COG4214	carbohydrate transport
NCG97_RS09340	COG4213	ABC transporter substrate-binding protein
NCG97_RS09345	COG1940	carbohydrate kinase activity
NCG97_RS09350	COG0395	ABC-type sugar transport system, permease component
NCG97_RS09355	COG1175	transmembrane transport
NCG97_RS09360	COG1653	transport
NCG97_RS09370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NCG97_RS09420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCG97_RS09455	COG0546	phosphoglycolate phosphatase activity
NCG97_RS09485	COG1024	Enoyl-CoA hydratase
NCG97_RS09500	COG0531	amino acid
NCG97_RS09505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NCG97_RS09515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NCG97_RS09550	COG1799	cell septum assembly
NCG97_RS09555	COG0598	Magnesium transport protein CorA
NCG97_RS09575	COG1733	regulation of RNA biosynthetic process
NCG97_RS09580	COG0142	geranyltranstransferase activity
NCG97_RS09630	COG2814	Major facilitator Superfamily
NCG97_RS09640	COG1191	sigma factor activity
NCG97_RS09660	COG1191	sigma factor activity
NCG97_RS09690	COG2770	Histidine kinase
NCG97_RS09690	COG2208	phosphoserine phosphatase activity
NCG97_RS09715	COG0302	gtp cyclohydrolase
NCG97_RS09855	COG1132	(ABC) transporter
NCG97_RS09870	COG1131	(ABC) transporter
NCG97_RS09890	COG0531	amino acid
NCG97_RS09900	COG0569	domain protein
NCG97_RS09935	COG0577	efflux transmembrane transporter activity
NCG97_RS09935	COG1136	(ABC) transporter
NCG97_RS09940	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NCG97_RS09945	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NCG97_RS09950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NCG97_RS09995	COG0745	RESPONSE REGULATOR receiver
NCG97_RS10010	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NCG97_RS10045	COG1435	thymidine kinase activity
NCG97_RS10065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NCG97_RS10070	COG1802	Transcriptional regulator
NCG97_RS10085	COG0612	Peptidase, M16
NCG97_RS10090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCG97_RS10100	COG0372	Belongs to the citrate synthase family
NCG97_RS10120	COG4565	transcriptional regulatory protein
NCG97_RS10125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NCG97_RS10135	COG2197	response regulator
NCG97_RS10150	COG0187	DNA topoisomerase II activity
NCG97_RS10165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NCG97_RS10170	COG2186	Transcriptional regulator
NCG97_RS10210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NCG97_RS10225	COG0488	(ABC) transporter
NCG97_RS10245	COG3226	Transcriptional regulator
NCG97_RS10260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NCG97_RS10265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NCG97_RS10270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NCG97_RS10320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NCG97_RS10345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NCG97_RS10360	COG1278	Cold shock
NCG97_RS10375	COG1126	abc transporter atp-binding protein
NCG97_RS10380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NCG97_RS10385	COG0765	amino acid transport
NCG97_RS10390	COG0765	amino acid transport
NCG97_RS10420	COG0628	permease
NCG97_RS10455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NCG97_RS10460	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS10470	COG0783	Belongs to the Dps family
NCG97_RS10475	COG1396	sequence-specific DNA binding
NCG97_RS10480	COG1546	Belongs to the CinA family
NCG97_RS10480	COG1058	Belongs to the CinA family
NCG97_RS10490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NCG97_RS10500	COG1674	ftsk spoiiie
NCG97_RS10510	COG4999	Histidine kinase
NCG97_RS10510	COG2205	protein histidine kinase activity
NCG97_RS10510	COG3437	response regulator, receiver
NCG97_RS10510	COG3850	Histidine kinase
NCG97_RS10550	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NCG97_RS10555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NCG97_RS10560	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NCG97_RS10580	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NCG97_RS10585	COG0612	Peptidase, M16
NCG97_RS10590	COG1185	polyribonucleotide nucleotidyltransferase activity
NCG97_RS10595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NCG97_RS10725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NCG97_RS10730	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NCG97_RS10740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NCG97_RS10750	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NCG97_RS10765	COG0779	Required for maturation of 30S ribosomal subunits
NCG97_RS10785	COG0442	prolyl-tRNA aminoacylation
NCG97_RS10805	COG0750	zinc metalloprotease
NCG97_RS10820	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS10845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NCG97_RS10850	COG1177	transmembrane transport
NCG97_RS10855	COG1176	ABC-type spermidine putrescine transport system, permease component I
NCG97_RS10860	COG3842	ATPase activity
NCG97_RS10880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NCG97_RS10890	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS10900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NCG97_RS10930	COG3842	ATPase activity
NCG97_RS10945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NCG97_RS10960	COG0233	cytoplasmic translational termination
NCG97_RS10965	COG0528	UMP kinase activity
NCG97_RS10975	COG0052	Belongs to the universal ribosomal protein uS2 family
NCG97_RS10990	COG1191	sigma factor activity
NCG97_RS11015	COG4974	Belongs to the 'phage' integrase family
NCG97_RS11025	COG0792	nuclease activity
NCG97_RS11050	COG0681	Belongs to the peptidase S26 family
NCG97_RS11065	COG0335	large ribosomal subunit rRNA binding
NCG97_RS11070	COG0336	Belongs to the RNA methyltransferase TrmD family
NCG97_RS11075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NCG97_RS11080	COG1837	Belongs to the UPF0109 family
NCG97_RS11085	COG0228	four-way junction DNA binding
NCG97_RS11140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NCG97_RS11150	COG0477	Major facilitator Superfamily
NCG97_RS11165	COG1254	Belongs to the acylphosphatase family
NCG97_RS11170	COG2340	Cysteine-rich secretory protein family
NCG97_RS11180	COG1733	regulation of RNA biosynthetic process
NCG97_RS11190	COG0571	ribonuclease III activity
NCG97_RS11195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NCG97_RS11210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NCG97_RS11215	COG0742	ribosomal rna small subunit methyltransferase
NCG97_RS11225	COG1461	Dihydroxyacetone kinase
NCG97_RS11230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NCG97_RS11255	COG1181	Belongs to the D-alanine--D-alanine ligase family
NCG97_RS11260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NCG97_RS11270	COG1920	GTP binding
NCG97_RS11280	COG0776	regulation of translation
NCG97_RS11290	COG0066	3-isopropylmalate dehydratase activity
NCG97_RS11295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NCG97_RS11300	COG1414	Transcriptional regulator
NCG97_RS11335	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NCG97_RS11340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NCG97_RS11345	COG0179	Fumarylacetoacetate (FAA) hydrolase
NCG97_RS11360	COG2018	Roadblock/LC7 domain
NCG97_RS11380	COG2018	Roadblock/LC7 domain
NCG97_RS11405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NCG97_RS11425	COG0477	Major facilitator Superfamily
NCG97_RS11435	COG1309	transcriptional regulator
NCG97_RS11440	COG2957	Belongs to the agmatine deiminase family
NCG97_RS11445	COG0804	urea catabolic process
NCG97_RS11450	COG0832	Belongs to the urease beta subunit family
NCG97_RS11450	COG0831	urea catabolic process
NCG97_RS11460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NCG97_RS11465	COG0473	3-isopropylmalate dehydrogenase activity
NCG97_RS11475	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS11480	COG0506	proline dehydrogenase activity
NCG97_RS11505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NCG97_RS11510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NCG97_RS11515	COG0440	acetolactate synthase activity
NCG97_RS11535	COG0667	Aldo Keto reductase
NCG97_RS11540	COG2133	pyrroloquinoline quinone binding
NCG97_RS11580	COG2409	Drug exporters of the RND superfamily
NCG97_RS11585	COG3511	phospholipase C
NCG97_RS11620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NCG97_RS11630	COG0154	amidase activity
NCG97_RS11635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NCG97_RS11650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NCG97_RS11670	COG4221	oxidoreductase activity
NCG97_RS11675	COG1611	Belongs to the LOG family
NCG97_RS11680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NCG97_RS11720	COG3903	Transcriptional regulator
NCG97_RS11720	COG3629	intracellular signal transduction
NCG97_RS11755	COG2860	membrane
NCG97_RS11760	COG0308	aminopeptidase N
NCG97_RS11765	COG4608	Belongs to the ABC transporter superfamily
NCG97_RS11770	COG0444	Belongs to the ABC transporter superfamily
NCG97_RS11780	COG0747	negative chemotaxis
NCG97_RS11805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NCG97_RS11810	COG0509	glycine decarboxylation via glycine cleavage system
NCG97_RS11815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NCG97_RS11855	COG0745	RESPONSE REGULATOR receiver
NCG97_RS11870	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NCG97_RS11880	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NCG97_RS11885	COG0785	Cytochrome C biogenesis protein
NCG97_RS11890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NCG97_RS11890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NCG97_RS11905	COG1376	ErfK ybiS ycfS ynhG family protein
NCG97_RS11925	COG1132	(ABC) transporter
NCG97_RS11935	COG1132	(ABC) transporter
NCG97_RS11960	COG4585	Histidine kinase
NCG97_RS11970	COG0366	Alpha amylase catalytic
NCG97_RS11985	COG1301	dicarboxylic acid transport
NCG97_RS11990	COG3290	protein histidine kinase activity
NCG97_RS11995	COG4565	transcriptional regulatory protein
NCG97_RS12005	COG1175	transmembrane transport
NCG97_RS12010	COG0395	ABC-type sugar transport system, permease component
NCG97_RS12020	COG1136	(ABC) transporter
NCG97_RS12020	COG0577	efflux transmembrane transporter activity
NCG97_RS12025	COG1136	(ABC) transporter
NCG97_RS12025	COG0577	efflux transmembrane transporter activity
NCG97_RS12030	COG0205	6-phosphofructokinase activity
NCG97_RS12035	COG0280	phosphate acetyltransferase
NCG97_RS12035	COG0857	belongs to the CobB CobQ family
NCG97_RS12040	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCG97_RS12080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NCG97_RS12090	COG2205	protein histidine kinase activity
NCG97_RS12095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NCG97_RS12095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NCG97_RS12155	COG0745	RESPONSE REGULATOR receiver
NCG97_RS12170	COG0183	Belongs to the thiolase family
NCG97_RS12225	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NCG97_RS12240	COG1250	3-hydroxyacyl-CoA dehydrogenase
NCG97_RS12270	COG2197	response regulator
NCG97_RS12280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NCG97_RS12285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NCG97_RS12290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NCG97_RS12295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NCG97_RS12305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NCG97_RS12310	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCG97_RS12335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCG97_RS12350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NCG97_RS12355	COG0254	rRNA binding
NCG97_RS12370	COG0083	homoserine kinase activity
NCG97_RS12380	COG0460	homoserine dehydrogenase
NCG97_RS12385	COG0019	diaminopimelate decarboxylase activity
NCG97_RS12390	COG0018	arginyl-trna synthetase
NCG97_RS12405	COG2124	cytochrome p450
NCG97_RS12420	COG0768	penicillin binding
NCG97_RS12430	COG1119	ATPase activity
NCG97_RS12440	COG0596	Alpha beta hydrolase
NCG97_RS12510	COG1357	PFAM Pentapeptide repeats (8 copies)
NCG97_RS12535	COG0745	RESPONSE REGULATOR receiver
NCG97_RS12545	COG0567	Dehydrogenase, E1 component
NCG97_RS12545	COG0508	dehydrogenase complex catalyzes the overall conversion of
NCG97_RS12635	COG0604	alcohol dehydrogenase
NCG97_RS12655	COG1126	abc transporter atp-binding protein
NCG97_RS12660	COG4106	trans-aconitate 2-methyltransferase activity
NCG97_RS12715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCG97_RS12720	COG1993	acr, cog1993
NCG97_RS12725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCG97_RS12730	COG0598	Magnesium transport protein CorA
NCG97_RS12750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NCG97_RS12765	COG2066	Belongs to the glutaminase family
NCG97_RS12780	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NCG97_RS12815	COG1597	lipid kinase activity
NCG97_RS12830	COG1309	transcriptional regulator
NCG97_RS12835	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS12840	COG0363	glucosamine-6-phosphate deaminase activity
NCG97_RS12850	COG0395	ABC-type sugar transport system, permease component
NCG97_RS12860	COG2182	Extracellular solute-binding protein
NCG97_RS12865	COG2188	Transcriptional regulator
NCG97_RS12890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NCG97_RS12915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NCG97_RS12935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NCG97_RS12935	COG2199	diguanylate cyclase activity
NCG97_RS12940	COG5662	AntiSigma factor
NCG97_RS12945	COG1595	DNA-templated transcription, initiation
NCG97_RS12980	COG2076	Multidrug Resistance protein
NCG97_RS12990	COG0483	inositol monophosphate 1-phosphatase activity
NCG97_RS12995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NCG97_RS12995	COG0517	IMP dehydrogenase activity
NCG97_RS13000	COG0753	catalase activity
NCG97_RS13040	COG1615	UPF0182 protein
NCG97_RS13050	COG3480	Lon protease (S16) C-terminal proteolytic domain
NCG97_RS13150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NCG97_RS13215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NCG97_RS13215	COG0596	Alpha beta hydrolase
NCG97_RS13260	COG1432	Conserved Protein
NCG97_RS13285	COG2814	Major facilitator Superfamily
NCG97_RS13295	COG0598	Magnesium transport protein CorA
NCG97_RS13330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NCG97_RS13345	COG1595	DNA-templated transcription, initiation
NCG97_RS13360	COG1024	Enoyl-CoA hydratase
NCG97_RS13375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NCG97_RS13380	COG1611	Belongs to the LOG family
NCG97_RS13385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NCG97_RS13425	COG2197	response regulator
NCG97_RS13430	COG4585	Histidine kinase
NCG97_RS13440	COG1131	(ABC) transporter
NCG97_RS13455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NCG97_RS13475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NCG97_RS13480	COG4166	transmembrane transport
NCG97_RS13485	COG0601	transmembrane transport
NCG97_RS13490	COG0444	Belongs to the ABC transporter superfamily
NCG97_RS13495	COG4608	Belongs to the ABC transporter superfamily
NCG97_RS13500	COG4608	Belongs to the ABC transporter superfamily
NCG97_RS13510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NCG97_RS13515	COG0601	transmembrane transport
NCG97_RS13525	COG1217	gtp-binding protein TYPA
NCG97_RS13590	COG0596	Alpha beta hydrolase
NCG97_RS13595	COG0288	reversible hydration of carbon dioxide
NCG97_RS13605	COG1414	Transcriptional regulator
NCG97_RS13610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NCG97_RS13630	COG4115	mRNA cleavage
NCG97_RS13635	COG2161	toxin-antitoxin pair type II binding
NCG97_RS13640	COG0012	GTP binding
NCG97_RS13655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NCG97_RS13665	COG1570	exodeoxyribonuclease VII activity
NCG97_RS13670	COG1722	exodeoxyribonuclease VII activity
NCG97_RS13675	COG0778	Nitroreductase
NCG97_RS13700	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NCG97_RS13700	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NCG97_RS13745	COG0114	fumarate hydratase activity
NCG97_RS13790	COG1136	(ABC) transporter
NCG97_RS13810	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NCG97_RS13820	COG0450	alkyl hydroperoxide reductase
NCG97_RS13825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NCG97_RS13840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NCG97_RS13845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NCG97_RS13870	COG2885	chlorophyll binding
NCG97_RS13915	COG2894	cell division
NCG97_RS13950	COG2610	gluconate transmembrane transporter activity
NCG97_RS13955	COG0251	oxidation-reduction process
NCG97_RS13960	COG1414	Transcriptional regulator
NCG97_RS13965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCG97_RS13975	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NCG97_RS13990	COG0436	Aminotransferase
NCG97_RS14020	COG1331	Highly conserved protein containing a thioredoxin domain
NCG97_RS14035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NCG97_RS14045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NCG97_RS14060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NCG97_RS14065	COG2255	four-way junction helicase activity
NCG97_RS14090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NCG97_RS14110	COG3293	Transposase
NCG97_RS14155	COG4221	oxidoreductase activity
NCG97_RS14180	COG4585	Histidine kinase
NCG97_RS14185	COG2197	response regulator
NCG97_RS14190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NCG97_RS14205	COG0456	acetyltransferase
NCG97_RS14205	COG0454	-acetyltransferase
NCG97_RS14210	COG1376	ErfK ybiS ycfS ynhG family protein
NCG97_RS14225	COG2986	histidine ammonia-lyase
NCG97_RS14240	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NCG97_RS14250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NCG97_RS14260	COG0768	penicillin binding
NCG97_RS14265	COG0424	maF-like protein
NCG97_RS14275	COG0693	protein deglycase activity
NCG97_RS14335	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NCG97_RS14345	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS14360	COG1595	DNA-templated transcription, initiation
NCG97_RS14365	COG0745	RESPONSE REGULATOR receiver
NCG97_RS14370	COG2205	protein histidine kinase activity
NCG97_RS14375	COG2205	protein histidine kinase activity
NCG97_RS14400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NCG97_RS14415	COG2814	Major facilitator Superfamily
NCG97_RS14455	COG1079	Belongs to the binding-protein-dependent transport system permease family
NCG97_RS14460	COG4603	Belongs to the binding-protein-dependent transport system permease family
NCG97_RS14465	COG3845	ABC transporter
NCG97_RS14470	COG1744	ABC transporter substrate-binding protein PnrA-like
NCG97_RS14485	COG2089	acid synthase
NCG97_RS14490	COG1083	cytidylyl-transferase
NCG97_RS14500	COG1216	Glycosyl transferase, family 2
NCG97_RS14530	COG3265	gluconokinase activity
NCG97_RS14535	COG2186	Transcriptional regulator
NCG97_RS14545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NCG97_RS14545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NCG97_RS14560	COG1595	DNA-templated transcription, initiation
NCG97_RS14575	COG2009	succinate dehydrogenase
NCG97_RS14585	COG1053	succinate dehydrogenase
NCG97_RS14590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NCG97_RS14635	COG1686	Belongs to the peptidase S11 family
NCG97_RS14650	COG0180	Tryptophanyl-tRNA synthetase
NCG97_RS14655	COG2124	cytochrome p450
NCG97_RS14660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NCG97_RS14710	COG0456	acetyltransferase
NCG97_RS14715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NCG97_RS14720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NCG97_RS14725	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NCG97_RS14735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NCG97_RS14770	COG4176	ABC-type proline glycine betaine transport system permease component
NCG97_RS14780	COG0517	IMP dehydrogenase activity
NCG97_RS14780	COG4175	Glycine betaine
NCG97_RS14790	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS14865	COG0039	L-malate dehydrogenase activity
NCG97_RS14900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NCG97_RS14915	COG0138	bifunctional purine biosynthesis protein purh
NCG97_RS14950	COG0045	succinate-CoA ligase (ADP-forming) activity
NCG97_RS14980	COG0714	Associated with various cellular activities
NCG97_RS14995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NCG97_RS15040	COG2197	response regulator
NCG97_RS15050	COG2815	serine threonine protein kinase
NCG97_RS15050	COG0515	serine threonine protein kinase
NCG97_RS15090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NCG97_RS15090	COG0519	Catalyzes the synthesis of GMP from XMP
NCG97_RS15110	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS15115	COG0515	serine threonine protein kinase
NCG97_RS15130	COG2814	Major facilitator Superfamily
NCG97_RS15140	COG4585	Histidine kinase
NCG97_RS15145	COG1366	Belongs to the anti-sigma-factor antagonist family
NCG97_RS15190	COG1131	(ABC) transporter
NCG97_RS15220	COG0596	Alpha beta hydrolase
NCG97_RS15220	COG2945	thiolester hydrolase activity
NCG97_RS15230	COG4821	SIS domain
NCG97_RS15250	COG1309	transcriptional regulator
NCG97_RS15260	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS15275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NCG97_RS15290	COG5006	permease, DMT superfamily
NCG97_RS15295	COG0583	DNA-binding transcription factor activity
NCG97_RS15330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NCG97_RS15365	COG0667	Aldo Keto reductase
NCG97_RS15390	COG2252	PERMEase
NCG97_RS15410	COG0681	Belongs to the peptidase S26 family
NCG97_RS15490	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NCG97_RS15545	COG1061	Type III restriction enzyme res subunit
NCG97_RS15560	COG3973	AAA domain
NCG97_RS15565	COG0515	serine threonine protein kinase
NCG97_RS15565	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NCG97_RS15570	COG3142	Participates in the control of copper homeostasis
NCG97_RS15605	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NCG97_RS15615	COG0745	RESPONSE REGULATOR receiver
NCG97_RS15645	COG0459	protein refolding
NCG97_RS15650	COG1278	Cold shock
NCG97_RS15665	COG0463	Glycosyl transferase, family 2
NCG97_RS15670	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NCG97_RS15720	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NCG97_RS15785	COG0745	RESPONSE REGULATOR receiver
NCG97_RS15790	COG2205	protein histidine kinase activity
NCG97_RS15810	COG3842	ATPase activity
NCG97_RS15845	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NCG97_RS15850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NCG97_RS15855	COG1329	Transcriptional regulator
NCG97_RS15895	COG0588	phosphoglycerate mutase activity
NCG97_RS15910	COG0438	transferase activity, transferring glycosyl groups
NCG97_RS15925	COG0667	Aldo Keto reductase
NCG97_RS15980	COG1131	(ABC) transporter
NCG97_RS15990	COG0456	acetyltransferase
NCG97_RS15995	COG0737	Belongs to the 5'-nucleotidase family
NCG97_RS16040	COG1609	Transcriptional regulator
NCG97_RS16045	COG0745	RESPONSE REGULATOR receiver
NCG97_RS16075	COG2897	thiosulfate sulfurtransferase activity
NCG97_RS16095	COG3485	protocatechuate 3,4-dioxygenase
NCG97_RS16100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NCG97_RS16105	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NCG97_RS16125	COG1490	D-aminoacyl-tRNA deacylase activity
NCG97_RS16145	COG0431	NADPH-dependent FMN reductase
NCG97_RS16150	COG1733	regulation of RNA biosynthetic process
NCG97_RS16175	COG0667	Aldo Keto reductase
NCG97_RS16190	COG2890	protein-(glutamine-N5) methyltransferase activity
NCG97_RS16240	COG0306	phosphate transporter
NCG97_RS16250	COG1937	Protein conserved in bacteria
NCG97_RS16270	COG0277	FAD linked oxidase domain protein
NCG97_RS16275	COG0671	phosphoesterase, PA-phosphatase related
NCG97_RS16280	COG0741	lytic transglycosylase activity
NCG97_RS16280	COG1196	nuclear chromosome segregation
NCG97_RS16280	COG0739	heme binding
NCG97_RS16335	COG0180	Tryptophanyl-tRNA synthetase
NCG97_RS16340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NCG97_RS16375	COG1595	DNA-templated transcription, initiation
NCG97_RS16395	COG0515	serine threonine protein kinase
NCG97_RS16395	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NCG97_RS16425	COG1082	Xylose isomerase domain protein TIM barrel
NCG97_RS16430	COG0248	Ppx GppA phosphatase
NCG97_RS16485	COG0671	phosphoesterase, PA-phosphatase related
NCG97_RS16495	COG1194	a g-specific adenine glycosylase
NCG97_RS16500	COG1595	DNA-templated transcription, initiation
NCG97_RS16510	COG0745	RESPONSE REGULATOR receiver
NCG97_RS16515	COG2205	protein histidine kinase activity
NCG97_RS16530	COG0739	heme binding
NCG97_RS16565	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NCG97_RS16585	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NCG97_RS16595	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NCG97_RS16610	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
NCG97_RS16620	COG0640	Transcriptional regulator
NCG97_RS16625	COG2197	response regulator
NCG97_RS16655	COG1174	glycine betaine transport
NCG97_RS16660	COG1174	glycine betaine transport
NCG97_RS16675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NCG97_RS16680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NCG97_RS16695	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NCG97_RS16695	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NCG97_RS16705	COG0302	gtp cyclohydrolase
NCG97_RS16730	COG2027	D-alanyl-D-alanine carboxypeptidase
NCG97_RS16735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NCG97_RS16750	COG0393	Putative heavy-metal-binding
NCG97_RS16755	COG0789	Transcriptional regulator
NCG97_RS16765	COG0655	NAD(P)H dehydrogenase (quinone) activity
NCG97_RS16780	COG2318	DinB family
NCG97_RS16785	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS16805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NCG97_RS16815	COG0254	rRNA binding
NCG97_RS16820	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NCG97_RS16830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCG97_RS16835	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NCG97_RS16840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NCG97_RS16840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NCG97_RS16890	COG1309	transcriptional regulator
NCG97_RS16905	COG3594	Acyltransferase
NCG97_RS16910	COG0584	glycerophosphoryl diester phosphodiesterase
NCG97_RS16915	COG2197	response regulator
NCG97_RS16940	COG0745	RESPONSE REGULATOR receiver
NCG97_RS16945	COG2205	protein histidine kinase activity
NCG97_RS16985	COG2124	cytochrome p450
NCG97_RS17000	COG0475	glutathione-regulated potassium exporter activity
NCG97_RS17030	COG3251	PFAM MbtH domain protein
NCG97_RS17035	COG2175	clavaminate synthase activity
NCG97_RS17075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS17090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS17100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS17115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS17160	COG2197	response regulator
NCG97_RS17165	COG4585	Histidine kinase
NCG97_RS17175	COG0515	serine threonine protein kinase
NCG97_RS17185	COG1132	(ABC) transporter
NCG97_RS17190	COG2197	response regulator
NCG97_RS17200	COG1136	(ABC) transporter
NCG97_RS17200	COG0577	efflux transmembrane transporter activity
NCG97_RS17220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NCG97_RS17225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NCG97_RS17230	COG1754	DNA topoisomerase type I activity
NCG97_RS17230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NCG97_RS17255	COG2890	protein-(glutamine-N5) methyltransferase activity
NCG97_RS17265	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NCG97_RS17270	COG2172	sigma factor antagonist activity
NCG97_RS17275	COG1366	Belongs to the anti-sigma-factor antagonist family
NCG97_RS17280	COG1111	helicase
NCG97_RS17280	COG1205	dead DEAH box helicase
NCG97_RS17340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NCG97_RS17345	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NCG97_RS17355	COG2267	carboxylic ester hydrolase activity
NCG97_RS17390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NCG97_RS17425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NCG97_RS17455	COG2188	Transcriptional regulator
NCG97_RS17465	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NCG97_RS17490	COG1316	TRANSCRIPTIONal
NCG97_RS17495	COG1215	transferase activity, transferring glycosyl groups
NCG97_RS17500	COG1309	transcriptional regulator
NCG97_RS17505	COG2124	cytochrome p450
NCG97_RS17540	COG1595	DNA-templated transcription, initiation
NCG97_RS17560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NCG97_RS17565	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NCG97_RS17600	COG4585	Histidine kinase
NCG97_RS17605	COG2197	response regulator
NCG97_RS17645	COG0531	amino acid
NCG97_RS17655	COG0577	efflux transmembrane transporter activity
NCG97_RS17655	COG1136	(ABC) transporter
NCG97_RS17660	COG0577	efflux transmembrane transporter activity
NCG97_RS17660	COG1136	(ABC) transporter
NCG97_RS17675	COG0745	RESPONSE REGULATOR receiver
NCG97_RS17680	COG2205	protein histidine kinase activity
NCG97_RS17700	COG2197	response regulator
NCG97_RS17705	COG2378	regulation of single-species biofilm formation
NCG97_RS17715	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NCG97_RS17780	COG2267	carboxylic ester hydrolase activity
NCG97_RS17790	COG1834	amidinotransferase
NCG97_RS17795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NCG97_RS17835	COG2268	Band 7 protein
NCG97_RS17925	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NCG97_RS17940	COG0590	tRNA wobble adenosine to inosine editing
NCG97_RS17965	COG1191	sigma factor activity
NCG97_RS17970	COG1191	sigma factor activity
NCG97_RS17990	COG0402	S-adenosylhomocysteine deaminase activity
NCG97_RS18005	COG0477	Major facilitator Superfamily
NCG97_RS18010	COG2353	YceI-like domain
NCG97_RS18020	COG0477	Major facilitator Superfamily
NCG97_RS18025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NCG97_RS18025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NCG97_RS18040	COG0745	RESPONSE REGULATOR receiver
NCG97_RS18045	COG0431	NADPH-dependent FMN reductase
NCG97_RS18045	COG1053	succinate dehydrogenase
NCG97_RS18045	COG3976	FMN-binding domain protein
NCG97_RS18065	COG2249	NAD(P)H dehydrogenase (quinone) activity
NCG97_RS18120	COG0784	Response regulator, receiver
NCG97_RS18125	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS18210	COG1595	DNA-templated transcription, initiation
NCG97_RS18225	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS18235	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS18270	COG3409	Peptidoglycan-binding domain 1 protein
NCG97_RS18270	COG5632	N-Acetylmuramoyl-L-alanine amidase
NCG97_RS18310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NCG97_RS18325	COG0653	protein targeting
NCG97_RS18345	COG0006	proline dipeptidase activity
NCG97_RS18350	COG1309	transcriptional regulator
NCG97_RS18385	COG2837	iron assimilation
NCG97_RS18390	COG0077	Prephenate dehydratase
NCG97_RS18400	COG0561	phosphatase activity
NCG97_RS18440	COG2186	Transcriptional regulator
NCG97_RS18470	COG1131	(ABC) transporter
NCG97_RS18495	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
NCG97_RS18510	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NCG97_RS18530	COG0561	phosphatase activity
NCG97_RS18535	COG0561	phosphatase activity
NCG97_RS18550	COG1294	oxidase, subunit
NCG97_RS18555	COG1271	oxidase subunit
NCG97_RS18560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NCG97_RS18565	COG1609	Transcriptional regulator
NCG97_RS18570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NCG97_RS18580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NCG97_RS18605	COG0662	Cupin 2, conserved barrel domain protein
NCG97_RS18610	COG1950	PFAM Membrane protein of
NCG97_RS18615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCG97_RS18620	COG0626	cystathionine gamma-synthase activity
NCG97_RS18665	COG2814	Major facilitator Superfamily
NCG97_RS18700	COG4977	sequence-specific DNA binding
NCG97_RS18730	COG0305	Participates in initiation and elongation during chromosome replication
NCG97_RS18745	COG0359	binds to the 23S rRNA
NCG97_RS18750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NCG97_RS18755	COG0629	single-stranded DNA binding
NCG97_RS18760	COG0360	Binds together with S18 to 16S ribosomal RNA
NCG97_RS18785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NCG97_RS18810	COG0617	tRNA 3'-terminal CCA addition
NCG97_RS18825	COG2815	serine threonine protein kinase
NCG97_RS18825	COG0515	serine threonine protein kinase
NCG97_RS18830	COG1595	DNA-templated transcription, initiation
NCG97_RS18840	COG0492	ferredoxin-NADP+ reductase activity
NCG97_RS18845	COG3118	belongs to the thioredoxin family
NCG97_RS18860	COG1192	Involved in chromosome partitioning
NCG97_RS18865	COG0357	Ribosomal RNA small subunit methyltransferase G
NCG97_RS18870	COG1847	R3H domain protein
NCG97_RS18875	COG0706	membrane insertase activity
NCG97_RS18880	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NCG97_RS18890	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NCG97_RS18900	COG0592	DNA-directed DNA polymerase activity
NCG97_RS18905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NCG97_RS18910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NCG97_RS18920	COG0187	DNA topoisomerase II activity
NCG97_RS18925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCG97_RS18985	COG0705	Rhomboid family
NCG97_RS19000	COG3764	Sortase (surface protein transpeptidase)
NCG97_RS19020	COG3764	Sortase (surface protein transpeptidase)
NCG97_RS19025	COG3764	Sortase (surface protein transpeptidase)
NCG97_RS19030	COG0515	serine threonine protein kinase
NCG97_RS19055	COG1716	ATPase activity
NCG97_RS19060	COG1716	ATPase activity
NCG97_RS19080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NCG97_RS19085	COG1733	regulation of RNA biosynthetic process
NCG97_RS19120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NCG97_RS19125	COG2151	metal-sulfur cluster biosynthetic enzyme
NCG97_RS19130	COG3396	Phenylacetate-CoA oxygenase
NCG97_RS19135	COG3460	Phenylacetate-CoA oxygenase
NCG97_RS19140	COG3396	Phenylacetate-CoA oxygenase
NCG97_RS19170	COG1309	transcriptional regulator
NCG97_RS19175	COG1522	sequence-specific DNA binding
NCG97_RS19225	COG0515	serine threonine protein kinase
NCG97_RS19230	COG0515	serine threonine protein kinase
NCG97_RS19250	COG0022	dehydrogenase e1 component
NCG97_RS19255	COG0508	dehydrogenase complex catalyzes the overall conversion of
NCG97_RS19330	COG3903	Transcriptional regulator
NCG97_RS19330	COG3629	intracellular signal transduction
NCG97_RS19335	COG1362	aminopeptidase activity
NCG97_RS19340	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS19365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NCG97_RS19380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NCG97_RS19390	COG2304	oxidoreductase activity
NCG97_RS19415	COG1174	glycine betaine transport
NCG97_RS19420	COG1174	glycine betaine transport
NCG97_RS19425	COG1732	Glycine betaine
NCG97_RS19435	COG0745	RESPONSE REGULATOR receiver
NCG97_RS19490	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NCG97_RS19520	COG3739	integral membrane protein
NCG97_RS19565	COG1316	TRANSCRIPTIONal
NCG97_RS19620	COG2197	response regulator
NCG97_RS19625	COG4585	Histidine kinase
NCG97_RS19670	COG2815	serine threonine protein kinase
NCG97_RS19670	COG0515	serine threonine protein kinase
NCG97_RS19705	COG0515	serine threonine protein kinase
NCG97_RS19705	COG2815	serine threonine protein kinase
NCG97_RS19720	COG2076	Multidrug Resistance protein
NCG97_RS19725	COG2076	Multidrug Resistance protein
NCG97_RS19770	COG0798	PFAM Bile acid sodium symporter
NCG97_RS19775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCG97_RS19845	COG1136	(ABC) transporter
NCG97_RS19870	COG0717	Belongs to the dCTP deaminase family
NCG97_RS19905	COG0247	lactate metabolic process
NCG97_RS19905	COG2181	nitrate reductase activity
NCG97_RS19910	COG0443	Heat shock 70 kDa protein
NCG97_RS19915	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NCG97_RS19920	COG0484	heat shock protein binding
NCG97_RS19925	COG0789	Transcriptional regulator
NCG97_RS19985	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NCG97_RS19990	COG0191	fructose-bisphosphate aldolase activity
NCG97_RS20010	COG3844	kynureninase activity
NCG97_RS20020	COG4585	Histidine kinase
NCG97_RS20035	COG3559	Exporter of polyketide antibiotics
NCG97_RS20040	COG1131	(ABC) transporter
NCG97_RS20055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NCG97_RS20075	COG0693	protein deglycase activity
NCG97_RS20085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NCG97_RS20090	COG1802	Transcriptional regulator
NCG97_RS20130	COG0583	DNA-binding transcription factor activity
NCG97_RS20140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NCG97_RS20150	COG2197	response regulator
NCG97_RS20165	COG1131	(ABC) transporter
NCG97_RS20185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NCG97_RS20190	COG0047	phosphoribosylformylglycinamidine synthase activity
NCG97_RS20195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NCG97_RS20205	COG1196	nuclear chromosome segregation
NCG97_RS20205	COG0741	lytic transglycosylase activity
NCG97_RS20205	COG0739	heme binding
NCG97_RS20220	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NCG97_RS20255	COG1643	Atp-dependent helicase
NCG97_RS20325	COG0513	Belongs to the DEAD box helicase family
NCG97_RS20330	COG1278	Cold shock
NCG97_RS20350	COG0667	Aldo Keto reductase
NCG97_RS20400	COG0579	oxidoreductase
NCG97_RS20440	COG1846	Transcriptional regulator
NCG97_RS20470	COG0123	including yeast histone deacetylase and acetoin utilization protein
NCG97_RS20520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NCG97_RS20525	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NCG97_RS20535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NCG97_RS20535	COG1648	precorrin-2 dehydrogenase activity
NCG97_RS20540	COG0113	porphobilinogen synthase activity
NCG97_RS20545	COG3237	CsbD-like
NCG97_RS20550	COG0018	arginyl-trna synthetase
NCG97_RS20555	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NCG97_RS20580	COG1690	Belongs to the RtcB family
NCG97_RS20585	COG1714	RDD family
NCG97_RS20600	COG1742	UPF0060 membrane protein
NCG97_RS20605	COG4181	ATPase activity
NCG97_RS20645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NCG97_RS20650	COG0406	alpha-ribazole phosphatase activity
NCG97_RS20665	COG0785	Cytochrome C biogenesis protein
NCG97_RS20670	COG1333	cytochrome c biogenesis protein
NCG97_RS20675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NCG97_RS20700	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NCG97_RS20705	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NCG97_RS20725	COG0163	prenyltransferase activity
NCG97_RS20750	COG1301	dicarboxylic acid transport
NCG97_RS20775	COG1278	Cold shock
NCG97_RS20780	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NCG97_RS20785	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NCG97_RS20795	COG2226	methyltransferase
NCG97_RS20830	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCG97_RS20835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCG97_RS20840	COG0649	NAD binding
NCG97_RS20850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NCG97_RS20860	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NCG97_RS20865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCG97_RS20870	COG0839	Belongs to the complex I subunit 6 family
NCG97_RS20875	COG0713	ATP synthesis coupled electron transport
NCG97_RS20880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NCG97_RS20890	COG1007	ATP synthesis coupled electron transport
NCG97_RS20910	COG0142	geranyltranstransferase activity
NCG97_RS20920	COG1131	(ABC) transporter
NCG97_RS20935	COG0702	epimerase
NCG97_RS20940	COG1013	pyruvate-flavodoxin oxidoreductase activity
NCG97_RS20945	COG0674	pyruvate-flavodoxin oxidoreductase activity
NCG97_RS20945	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NCG97_RS20955	COG4585	Histidine kinase
NCG97_RS20960	COG4585	Histidine kinase
NCG97_RS20980	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCG97_RS20985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCG97_RS20995	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NCG97_RS21000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCG97_RS21010	COG0713	ATP synthesis coupled electron transport
NCG97_RS21035	COG3304	Inner membrane component domain
NCG97_RS21045	COG1666	GTP binding
NCG97_RS21055	COG0702	epimerase
NCG97_RS21060	COG0402	S-adenosylhomocysteine deaminase activity
NCG97_RS21075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NCG97_RS21080	COG2030	dehydratase
NCG97_RS21095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NCG97_RS21100	COG0436	Aminotransferase
NCG97_RS21115	COG0250	Participates in transcription elongation, termination and antitermination
NCG97_RS21120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NCG97_RS21125	COG0081	regulation of translation
NCG97_RS21130	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NCG97_RS21135	COG0222	ribosome binding
NCG97_RS21140	COG0085	RNA polymerase activity
NCG97_RS21145	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCG97_RS21155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NCG97_RS21160	COG0049	tRNA binding
NCG97_RS21165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NCG97_RS21170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NCG97_RS21175	COG0051	transcription antitermination factor activity, RNA binding
NCG97_RS21180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NCG97_RS21185	COG0088	Forms part of the polypeptide exit tunnel
NCG97_RS21190	COG0089	rRNA binding
NCG97_RS21195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NCG97_RS21200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NCG97_RS21205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NCG97_RS21210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NCG97_RS21215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NCG97_RS21220	COG0255	Belongs to the universal ribosomal protein uL29 family
NCG97_RS21225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NCG97_RS21230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NCG97_RS21235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NCG97_RS21240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NCG97_RS21245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCG97_RS21250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NCG97_RS21255	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NCG97_RS21260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NCG97_RS21270	COG1841	ribosomal large subunit assembly
NCG97_RS21275	COG0200	Binds to the 23S rRNA
NCG97_RS21285	COG0563	adenylate kinase activity
NCG97_RS21295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NCG97_RS21300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NCG97_RS21305	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NCG97_RS21315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NCG97_RS21320	COG0202	RNA polymerase activity
NCG97_RS21325	COG0203	ribosomal protein L17
NCG97_RS21330	COG0101	tRNA pseudouridine synthase activity
NCG97_RS21345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NCG97_RS21350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NCG97_RS21355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NCG97_RS21380	COG0736	holo-[acyl-carrier-protein] synthase activity
NCG97_RS21425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NCG97_RS21445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NCG97_RS21460	COG4221	oxidoreductase activity
NCG97_RS21470	COG0583	DNA-binding transcription factor activity
NCG97_RS21500	COG0516	GMP reductase activity
NCG97_RS21510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NCG97_RS21555	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS21595	COG1024	Enoyl-CoA hydratase
NCG97_RS21615	COG0259	pyridoxamine-phosphate oxidase activity
NCG97_RS21645	COG3391	amine dehydrogenase activity
NCG97_RS21690	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NCG97_RS21755	COG2319	Wd-40 repeat
NCG97_RS21765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS21820	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NCG97_RS21850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCG97_RS21860	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS21865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NCG97_RS21890	COG1686	Belongs to the peptidase S11 family
NCG97_RS21915	COG0514	ATP-dependent DNA helicase (RecQ)
NCG97_RS21935	COG2197	response regulator
NCG97_RS21940	COG0154	amidase activity
NCG97_RS21990	COG0297	glycogen (starch) synthase activity
NCG97_RS22010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCG97_RS22055	COG4974	Belongs to the 'phage' integrase family
NCG97_RS22085	COG1309	transcriptional regulator
NCG97_RS22105	COG1846	Transcriptional regulator
NCG97_RS22130	COG1247	-acetyltransferase
NCG97_RS22140	COG1349	DNA-binding transcription factor activity
NCG97_RS22180	COG0431	NADPH-dependent FMN reductase
NCG97_RS22280	COG2188	Transcriptional regulator
NCG97_RS22290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NCG97_RS22300	COG1970	mechanosensitive ion channel activity
NCG97_RS22325	COG3263	regulation of cellular component size
NCG97_RS22335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NCG97_RS22340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NCG97_RS22350	COG0315	cyclic pyranopterin monophosphate synthase activity
NCG97_RS22355	COG0521	Mo-molybdopterin cofactor biosynthetic process
NCG97_RS22355	COG0315	cyclic pyranopterin monophosphate synthase activity
NCG97_RS22390	COG0789	Transcriptional regulator
NCG97_RS22395	COG1725	Transcriptional regulator
NCG97_RS22405	COG1131	(ABC) transporter
NCG97_RS22415	COG0708	Exodeoxyribonuclease III
NCG97_RS22430	COG3629	intracellular signal transduction
NCG97_RS22430	COG3903	Transcriptional regulator
NCG97_RS22445	COG2072	flavoprotein involved in K transport
NCG97_RS22450	COG2267	carboxylic ester hydrolase activity
NCG97_RS22455	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS22480	COG4946	Tricorn protease homolog
NCG97_RS22480	COG0793	Belongs to the peptidase S41A family
NCG97_RS22520	COG0768	penicillin binding
NCG97_RS22540	COG0084	hydrolase, TatD family'
NCG97_RS22605	COG2226	methyltransferase
NCG97_RS22605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS22605	COG3433	isochorismatase activity
NCG97_RS22620	COG1280	lysine exporter protein (LysE YggA)
NCG97_RS22690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NCG97_RS22695	COG2197	response regulator
NCG97_RS22700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NCG97_RS22720	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS22730	COG4106	trans-aconitate 2-methyltransferase activity
NCG97_RS22735	COG1309	transcriptional regulator
NCG97_RS22745	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NCG97_RS22755	COG0193	aminoacyl-tRNA hydrolase activity
NCG97_RS22760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NCG97_RS22765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NCG97_RS22770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NCG97_RS22810	COG1316	TRANSCRIPTIONal
NCG97_RS22825	COG2814	Major facilitator Superfamily
NCG97_RS22860	COG2815	serine threonine protein kinase
NCG97_RS22860	COG0515	serine threonine protein kinase
NCG97_RS22875	COG2814	Major facilitator Superfamily
NCG97_RS22900	COG0148	phosphopyruvate hydratase activity
NCG97_RS22930	COG0577	efflux transmembrane transporter activity
NCG97_RS22930	COG1136	(ABC) transporter
NCG97_RS22935	COG1136	(ABC) transporter
NCG97_RS22935	COG0577	efflux transmembrane transporter activity
NCG97_RS23005	COG1609	Transcriptional regulator
NCG97_RS23020	COG1174	glycine betaine transport
NCG97_RS23025	COG1174	glycine betaine transport
NCG97_RS23070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NCG97_RS23075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NCG97_RS23090	COG1191	sigma factor activity
NCG97_RS23095	COG1366	Belongs to the anti-sigma-factor antagonist family
NCG97_RS23125	COG3104	oligopeptide transport
NCG97_RS23130	COG0745	RESPONSE REGULATOR receiver
NCG97_RS23135	COG2205	protein histidine kinase activity
NCG97_RS23155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NCG97_RS23175	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NCG97_RS23200	COG1316	TRANSCRIPTIONal
NCG97_RS23215	COG1316	TRANSCRIPTIONal
NCG97_RS23245	COG0778	Nitroreductase
NCG97_RS23245	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NCG97_RS23250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NCG97_RS23300	COG1482	cell wall glycoprotein biosynthetic process
NCG97_RS23310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NCG97_RS23310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NCG97_RS23310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NCG97_RS23315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NCG97_RS23375	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NCG97_RS23380	COG0745	RESPONSE REGULATOR receiver
NCG97_RS23390	COG0823	Involved in the tonB-independent uptake of proteins
NCG97_RS23400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NCG97_RS23405	COG2197	response regulator
NCG97_RS23410	COG3214	Protein conserved in bacteria
NCG97_RS23420	COG0653	protein targeting
NCG97_RS23435	COG0546	phosphoglycolate phosphatase activity
NCG97_RS23440	COG2902	Dehydrogenase
NCG97_RS23445	COG1134	teichoic acid transport
NCG97_RS23455	COG1309	transcriptional regulator
NCG97_RS23460	COG0463	Glycosyl transferase, family 2
NCG97_RS23460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NCG97_RS23465	COG1215	transferase activity, transferring glycosyl groups
NCG97_RS23485	COG2226	methyltransferase
NCG97_RS23500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NCG97_RS23520	COG0395	ABC-type sugar transport system, permease component
NCG97_RS23530	COG1653	transport
NCG97_RS23540	COG0515	serine threonine protein kinase
NCG97_RS23545	COG0515	serine threonine protein kinase
NCG97_RS23550	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NCG97_RS23565	COG2884	Cell division ATP-binding protein ftsE
NCG97_RS23570	COG2177	Part of the ABC transporter FtsEX involved in
NCG97_RS23575	COG0793	Belongs to the peptidase S41A family
NCG97_RS23580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NCG97_RS23595	COG0583	DNA-binding transcription factor activity
NCG97_RS23615	COG2223	nitrite transmembrane transporter activity
NCG97_RS23625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NCG97_RS23650	COG3973	AAA domain
NCG97_RS23660	COG0776	regulation of translation
NCG97_RS23670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCG97_RS23675	COG1678	Uncharacterized ACR, COG1678
NCG97_RS23760	COG1174	glycine betaine transport
NCG97_RS23765	COG1125	glycine betaine transport
NCG97_RS23765	COG0517	IMP dehydrogenase activity
NCG97_RS23770	COG1174	glycine betaine transport
NCG97_RS23780	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NCG97_RS23810	COG0222	ribosome binding
NCG97_RS23815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NCG97_RS23850	COG1335	isochorismatase
NCG97_RS23860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NCG97_RS23870	COG1113	amino acid transport
NCG97_RS23900	COG1263	PTS System
NCG97_RS23905	COG1263	PTS System
NCG97_RS23910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NCG97_RS23930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NCG97_RS23950	COG0477	Major facilitator Superfamily
NCG97_RS23960	COG2205	protein histidine kinase activity
NCG97_RS23975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NCG97_RS24020	COG2733	membrane
NCG97_RS24025	COG3764	Sortase (surface protein transpeptidase)
NCG97_RS24095	COG0179	Fumarylacetoacetate (FAA) hydrolase
NCG97_RS24185	COG1126	abc transporter atp-binding protein
NCG97_RS24190	COG0765	amino acid transport
NCG97_RS24195	COG0765	amino acid transport
NCG97_RS24230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS24290	COG0492	ferredoxin-NADP+ reductase activity
NCG97_RS24300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NCG97_RS24315	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NCG97_RS24335	COG3979	chitinase
NCG97_RS24345	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NCG97_RS24360	COG0589	response to stress
NCG97_RS24365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NCG97_RS24380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NCG97_RS24390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCG97_RS24395	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS24410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NCG97_RS24415	COG1309	transcriptional regulator
NCG97_RS24425	COG1946	Acyl-CoA thioesterase
NCG97_RS24430	COG0586	Pfam SNARE associated Golgi protein
NCG97_RS24435	COG3963	phosphatidate phosphatase activity
NCG97_RS24470	COG0028	Belongs to the TPP enzyme family
NCG97_RS24475	COG1309	transcriptional regulator
NCG97_RS24485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NCG97_RS24505	COG1472	Belongs to the glycosyl hydrolase 3 family
NCG97_RS24520	COG0673	inositol 2-dehydrogenase activity
NCG97_RS24535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NCG97_RS24550	COG2608	mercury ion transmembrane transporter activity
NCG97_RS24555	COG0586	Pfam SNARE associated Golgi protein
NCG97_RS24560	COG0673	inositol 2-dehydrogenase activity
NCG97_RS24565	COG1609	Transcriptional regulator
NCG97_RS24575	COG3409	Peptidoglycan-binding domain 1 protein
NCG97_RS24580	COG2814	Major facilitator Superfamily
NCG97_RS24585	COG0673	inositol 2-dehydrogenase activity
NCG97_RS24595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCG97_RS24605	COG3718	enzyme involved in inositol metabolism
NCG97_RS24625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NCG97_RS24645	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NCG97_RS24660	COG0596	Alpha beta hydrolase
NCG97_RS24690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NCG97_RS24715	COG3321	synthase
NCG97_RS24715	COG0604	alcohol dehydrogenase
NCG97_RS24715	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS24740	COG1113	amino acid transport
NCG97_RS24755	COG1063	alcohol dehydrogenase
NCG97_RS24770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NCG97_RS24775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NCG97_RS24800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS24815	COG0583	DNA-binding transcription factor activity
NCG97_RS24820	COG2226	methyltransferase
NCG97_RS24840	COG0604	alcohol dehydrogenase
NCG97_RS24845	COG1902	pentaerythritol trinitrate reductase activity
NCG97_RS24865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NCG97_RS24900	COG1136	(ABC) transporter
NCG97_RS24920	COG2346	COG2346, Truncated hemoglobins
NCG97_RS24945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NCG97_RS24955	COG2186	Transcriptional regulator
NCG97_RS24970	COG1486	melibiose metabolic process
NCG97_RS24975	COG1846	Transcriptional regulator
NCG97_RS24975	COG1940	carbohydrate kinase activity
NCG97_RS24980	COG0668	transmembrane transport
NCG97_RS25030	COG4266	Belongs to the allantoicase family
NCG97_RS25065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NCG97_RS25070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NCG97_RS25075	COG1113	amino acid transport
NCG97_RS25080	COG1113	amino acid transport
NCG97_RS25090	COG1113	amino acid transport
NCG97_RS25095	COG0698	ribose 5-phosphate isomerase
NCG97_RS25105	COG4552	Acetyltransferase involved in intracellular survival and related
NCG97_RS25115	COG3594	Acyltransferase
NCG97_RS25140	COG0544	peptidyl-prolyl cis-trans isomerase activity
NCG97_RS25145	COG0740	serine-type endopeptidase activity
NCG97_RS25150	COG0740	serine-type endopeptidase activity
NCG97_RS25155	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NCG97_RS25165	COG0525	valine-tRNA ligase activity
NCG97_RS25185	COG0105	UTP biosynthetic process
NCG97_RS25190	COG1077	Cell shape determining protein MreB Mrl
NCG97_RS25205	COG0768	penicillin binding
NCG97_RS25210	COG0772	Belongs to the SEDS family
NCG97_RS25250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NCG97_RS25255	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NCG97_RS25260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NCG97_RS25270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NCG97_RS25280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NCG97_RS25295	COG0501	Belongs to the peptidase M48B family
NCG97_RS25310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NCG97_RS25320	COG0799	negative regulation of ribosome biogenesis
NCG97_RS25325	COG0588	phosphoglycerate mutase activity
NCG97_RS25360	COG0495	leucyl-tRNA aminoacylation
NCG97_RS25370	COG1307	EDD domain protein, DegV family
NCG97_RS25385	COG1959	2 iron, 2 sulfur cluster binding
NCG97_RS25390	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NCG97_RS25410	COG0268	Binds directly to 16S ribosomal RNA
NCG97_RS25415	COG0481	GTPase activity
NCG97_RS25420	COG1022	Amp-dependent synthetase and ligase
NCG97_RS25450	COG1420	regulation of RNA biosynthetic process
NCG97_RS25455	COG0484	heat shock protein binding
NCG97_RS25490	COG0537	adenosine 5'-monophosphoramidase activity
NCG97_RS25495	COG1234	tRNA 3'-trailer cleavage
NCG97_RS25505	COG4948	Mandelate Racemase Muconate Lactonizing
NCG97_RS25550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NCG97_RS25575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NCG97_RS25580	COG2211	Major facilitator Superfamily
NCG97_RS25600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NCG97_RS25605	COG2755	lipolytic protein G-D-S-L family
NCG97_RS25620	COG2124	cytochrome p450
NCG97_RS25650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NCG97_RS25660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NCG97_RS25665	COG1121	(ABC) transporter
NCG97_RS25675	COG0423	glycine-tRNA ligase activity
NCG97_RS25710	COG1309	transcriptional regulator
NCG97_RS25715	COG0667	Aldo Keto reductase
NCG97_RS25760	COG0477	Major facilitator Superfamily
NCG97_RS25770	COG0519	Catalyzes the synthesis of GMP from XMP
NCG97_RS25770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NCG97_RS25775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NCG97_RS25775	COG0574	Belongs to the PEP-utilizing enzyme family
NCG97_RS25795	COG0395	ABC-type sugar transport system, permease component
NCG97_RS25800	COG1175	transmembrane transport
NCG97_RS25855	COG0531	amino acid
NCG97_RS25870	COG0640	Transcriptional regulator
NCG97_RS25885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NCG97_RS25885	COG2146	nitrite reductase [NAD(P)H] activity
NCG97_RS25940	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NCG97_RS25975	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NCG97_RS25995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NCG97_RS26065	COG0588	phosphoglycerate mutase activity
NCG97_RS26120	COG0500	methyltransferase
NCG97_RS26150	COG0477	Major facilitator Superfamily
NCG97_RS26165	COG1764	response to oxidative stress
NCG97_RS26180	COG1129	ABC transporter
NCG97_RS26190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCG97_RS26245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NCG97_RS26250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NCG97_RS26255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NCG97_RS26280	COG0789	Transcriptional regulator
NCG97_RS26285	COG0667	Aldo Keto reductase
NCG97_RS26295	COG2197	response regulator
NCG97_RS26315	COG1309	transcriptional regulator
NCG97_RS26320	COG0477	Major facilitator Superfamily
NCG97_RS26330	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NCG97_RS26385	COG0586	Pfam SNARE associated Golgi protein
NCG97_RS26390	COG4585	Histidine kinase
NCG97_RS26425	COG2186	Transcriptional regulator
NCG97_RS26450	COG0583	DNA-binding transcription factor activity
NCG97_RS26470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NCG97_RS26475	COG1024	Enoyl-CoA hydratase
NCG97_RS26480	COG2259	Doxx family
NCG97_RS26490	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NCG97_RS26495	COG0596	Alpha beta hydrolase
NCG97_RS26510	COG1072	(Pantothenic acid kinase))
NCG97_RS26560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NCG97_RS26595	COG0477	Major facilitator Superfamily
NCG97_RS26610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NCG97_RS26635	COG2124	cytochrome p450
NCG97_RS26640	COG0183	Belongs to the thiolase family
NCG97_RS26650	COG3845	ABC transporter
NCG97_RS26670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NCG97_RS26685	COG1309	transcriptional regulator
NCG97_RS26690	COG0438	transferase activity, transferring glycosyl groups
NCG97_RS26710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS26720	COG0860	N-Acetylmuramoyl-L-alanine amidase
NCG97_RS26730	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS26735	COG0183	Belongs to the thiolase family
NCG97_RS26745	COG2197	response regulator
NCG97_RS26765	COG1131	(ABC) transporter
NCG97_RS26810	COG0800	Aldolase
NCG97_RS26840	COG2070	2-Nitropropane dioxygenase
NCG97_RS26855	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS26870	COG2814	Major facilitator Superfamily
NCG97_RS26910	COG0672	)-iron permease
NCG97_RS26915	COG2837	iron assimilation
NCG97_RS26930	COG5398	heme oxygenase
NCG97_RS26955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NCG97_RS26960	COG2186	Transcriptional regulator
NCG97_RS26975	COG1175	transmembrane transport
NCG97_RS26995	COG1994	Peptidase M50
NCG97_RS27015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NCG97_RS27020	COG0477	Major facilitator Superfamily
NCG97_RS27025	COG1309	transcriptional regulator
NCG97_RS27045	COG2132	Multicopper oxidase
NCG97_RS27050	COG0174	glutamine synthetase
NCG97_RS27075	COG1609	Transcriptional regulator
NCG97_RS27080	COG0366	Alpha amylase catalytic
NCG97_RS27085	COG2182	Extracellular solute-binding protein
NCG97_RS27090	COG1175	transmembrane transport
NCG97_RS27095	COG0395	ABC-type sugar transport system, permease component
NCG97_RS27100	COG0366	Alpha amylase catalytic
NCG97_RS27235	COG0745	RESPONSE REGULATOR receiver
NCG97_RS27265	COG1695	Transcriptional regulator
NCG97_RS27270	COG1902	pentaerythritol trinitrate reductase activity
NCG97_RS27270	COG0446	pyridine nucleotide-disulphide oxidoreductase
NCG97_RS27290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NCG97_RS27290	COG0515	serine threonine protein kinase
NCG97_RS27340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NCG97_RS27345	COG0321	lipoyl(octanoyl) transferase activity
NCG97_RS27385	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS27405	COG0508	dehydrogenase complex catalyzes the overall conversion of
NCG97_RS27410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NCG97_RS27415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NCG97_RS27420	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NCG97_RS27435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NCG97_RS27435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NCG97_RS27440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NCG97_RS27480	COG2197	response regulator
NCG97_RS27490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NCG97_RS27500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NCG97_RS27520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCG97_RS27530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NCG97_RS27535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NCG97_RS27545	COG1376	ErfK ybiS ycfS ynhG family protein
NCG97_RS27555	COG1845	cytochrome c oxidase, subunit III
NCG97_RS27560	COG2010	Cytochrome c
NCG97_RS27565	COG0723	plastoquinol--plastocyanin reductase activity
NCG97_RS27570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NCG97_RS27575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NCG97_RS27630	COG0438	transferase activity, transferring glycosyl groups
NCG97_RS27650	COG0003	Pfam Anion-transporting ATPase
NCG97_RS27660	COG1940	carbohydrate kinase activity
NCG97_RS27690	COG2197	response regulator
NCG97_RS27695	COG0205	6-phosphofructokinase activity
NCG97_RS27700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCG97_RS27710	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NCG97_RS27720	COG2193	ferroxidase activity
NCG97_RS27725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NCG97_RS27735	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NCG97_RS27745	COG2022	thiamine diphosphate biosynthetic process
NCG97_RS27770	COG0352	thiamine-phosphate diphosphorylase activity
NCG97_RS27785	COG1233	COG1233 Phytoene dehydrogenase and related
NCG97_RS27795	COG1309	transcriptional regulator
NCG97_RS27815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NCG97_RS27845	COG0275	rRNA processing
NCG97_RS27860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NCG97_RS27865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NCG97_RS27870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NCG97_RS27885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NCG97_RS27905	COG1799	cell septum assembly
NCG97_RS27930	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NCG97_RS27985	COG0587	DNA-directed DNA polymerase activity
NCG97_RS27995	COG1432	Conserved Protein
NCG97_RS28015	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NCG97_RS28030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NCG97_RS28035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NCG97_RS28040	COG0131	Imidazoleglycerol-phosphate dehydratase
NCG97_RS28050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NCG97_RS28055	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NCG97_RS28080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NCG97_RS28085	COG1053	succinate dehydrogenase
NCG97_RS28095	COG0583	DNA-binding transcription factor activity
NCG97_RS28110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NCG97_RS28135	COG0134	indole-3-glycerol-phosphate synthase activity
NCG97_RS28140	COG0133	tryptophan synthase activity
NCG97_RS28155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NCG97_RS28195	COG0067	glutamate synthase
NCG97_RS28195	COG0069	glutamate synthase activity
NCG97_RS28195	COG0070	glutamate synthase
NCG97_RS28210	COG0640	Transcriptional regulator
NCG97_RS28215	COG1846	Transcriptional regulator
NCG97_RS28225	COG3467	pyridoxamine 5'-phosphate
NCG97_RS28235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NCG97_RS28275	COG0366	Alpha amylase catalytic
NCG97_RS28275	COG1470	cell adhesion involved in biofilm formation
NCG97_RS28365	COG2050	protein possibly involved in aromatic compounds catabolism
NCG97_RS28430	COG0237	dephospho-CoA kinase activity
NCG97_RS28510	COG0584	glycerophosphoryl diester phosphodiesterase
NCG97_RS28515	COG0556	nucleotide-excision repair
NCG97_RS28555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NCG97_RS28565	COG1609	Transcriptional regulator
NCG97_RS28590	COG0322	excinuclease ABC activity
NCG97_RS28595	COG1660	Displays ATPase and GTPase activities
NCG97_RS28605	COG1481	regulation of sporulation
NCG97_RS28610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NCG97_RS28615	COG0126	phosphoglycerate kinase activity
NCG97_RS28620	COG0149	triose-phosphate isomerase activity
NCG97_RS28625	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NCG97_RS28640	COG0166	Belongs to the GPI family
NCG97_RS28645	COG0363	glucosamine-6-phosphate deaminase activity
NCG97_RS28660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NCG97_RS28670	COG0109	protoheme IX farnesyltransferase activity
NCG97_RS28715	COG0719	Fe-S assembly protein
NCG97_RS28725	COG0396	ATPase activity
NCG97_RS28735	COG0822	iron-sulfur transferase activity
NCG97_RS28740	COG2151	metal-sulfur cluster biosynthetic enzyme
NCG97_RS28745	COG2076	Multidrug Resistance protein
NCG97_RS28750	COG3226	Transcriptional regulator
NCG97_RS28755	COG2171	N-acyltransferase activity
NCG97_RS28765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NCG97_RS28800	COG2261	transglycosylase associated protein
NCG97_RS28805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NCG97_RS28810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NCG97_RS28825	COG1414	Transcriptional regulator
NCG97_RS28840	COG2226	methyltransferase
NCG97_RS28855	COG1902	pentaerythritol trinitrate reductase activity
NCG97_RS28865	COG1917	Cupin 2, conserved barrel domain protein
NCG97_RS28870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NCG97_RS28895	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NCG97_RS28905	COG1797	cobyrinic acid a,c-diamide synthase activity
NCG97_RS28925	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NCG97_RS28945	COG1653	transport
NCG97_RS28980	COG0488	(ABC) transporter
NCG97_RS29000	COG1302	Protein conserved in bacteria
NCG97_RS29030	COG3387	PFAM Glycoside hydrolase 15-related
NCG97_RS29045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NCG97_RS29100	COG1404	Belongs to the peptidase S8 family
NCG97_RS29110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NCG97_RS29115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NCG97_RS29135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NCG97_RS29150	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS29155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NCG97_RS29160	COG2186	Transcriptional regulator
NCG97_RS29220	COG2197	response regulator
NCG97_RS29240	COG1119	ATPase activity
NCG97_RS29265	COG1881	PFAM PEBP family protein
NCG97_RS29275	COG2094	Belongs to the DNA glycosylase MPG family
NCG97_RS29315	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NCG97_RS29330	COG0647	UMP catabolic process
NCG97_RS29380	COG0497	DNA recombination
NCG97_RS29390	COG4941	Belongs to the sigma-70 factor family
NCG97_RS29395	COG3795	YCII-related domain
NCG97_RS29425	COG3387	PFAM Glycoside hydrolase 15-related
NCG97_RS29430	COG0504	CTP synthase activity
NCG97_RS29435	COG0494	nUDIX hydrolase
NCG97_RS29445	COG0686	Belongs to the AlaDH PNT family
NCG97_RS29460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NCG97_RS29465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NCG97_RS29470	COG1187	pseudouridine synthase activity
NCG97_RS29500	COG1160	GTP binding
NCG97_RS29540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NCG97_RS29550	COG0671	phosphoesterase, PA-phosphatase related
NCG97_RS29570	COG1799	cell septum assembly
NCG97_RS29580	COG0330	HflC and HflK could
NCG97_RS29610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NCG97_RS29640	COG0531	amino acid
NCG97_RS29645	COG1522	sequence-specific DNA binding
NCG97_RS29670	COG1725	Transcriptional regulator
NCG97_RS29675	COG1834	amidinotransferase
NCG97_RS29700	COG1012	belongs to the aldehyde dehydrogenase family
NCG97_RS29770	COG2197	response regulator
NCG97_RS29785	COG4865	methylaspartate mutase activity
NCG97_RS29795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS29820	COG0367	asparagine synthase
NCG97_RS29830	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS29865	COG2188	Transcriptional regulator
NCG97_RS29880	COG2851	Citrate transporter
NCG97_RS29905	COG0477	Major facilitator Superfamily
NCG97_RS29925	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS29965	COG0477	Major facilitator Superfamily
NCG97_RS29980	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS29985	COG1309	transcriptional regulator
NCG97_RS29990	COG3963	phosphatidate phosphatase activity
NCG97_RS30020	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NCG97_RS30060	COG2205	protein histidine kinase activity
NCG97_RS30065	COG0745	RESPONSE REGULATOR receiver
NCG97_RS30085	COG0488	(ABC) transporter
NCG97_RS30135	COG0515	serine threonine protein kinase
NCG97_RS30135	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NCG97_RS30145	COG0564	pseudouridine synthase activity
NCG97_RS30155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NCG97_RS30185	COG0667	Aldo Keto reductase
NCG97_RS30190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS30200	COG0598	Magnesium transport protein CorA
NCG97_RS30220	COG0215	cysteine-tRNA ligase activity
NCG97_RS30235	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS30270	COG2186	Transcriptional regulator
NCG97_RS30280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NCG97_RS30285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NCG97_RS30290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NCG97_RS30295	COG1414	Transcriptional regulator
NCG97_RS30300	COG0646	methionine synthase
NCG97_RS30300	COG1410	methionine synthase
NCG97_RS30310	COG4166	transmembrane transport
NCG97_RS30320	COG2197	response regulator
NCG97_RS30330	COG1994	Peptidase M50
NCG97_RS30330	COG0517	IMP dehydrogenase activity
NCG97_RS30350	COG1222	aaa ATPase
NCG97_RS30355	COG4122	O-methyltransferase activity
NCG97_RS30370	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NCG97_RS30375	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NCG97_RS30380	COG1609	Transcriptional regulator
NCG97_RS30390	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NCG97_RS30395	COG0545	Peptidyl-prolyl cis-trans isomerase
NCG97_RS30425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NCG97_RS30430	COG0805	protein transport
NCG97_RS30465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NCG97_RS30470	COG4175	Glycine betaine
NCG97_RS30470	COG0517	IMP dehydrogenase activity
NCG97_RS30510	COG2186	Transcriptional regulator
NCG97_RS30525	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS30565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NCG97_RS30570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NCG97_RS30575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NCG97_RS30580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NCG97_RS30585	COG5002	protein histidine kinase activity
NCG97_RS30590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NCG97_RS30655	COG1649	PFAM Uncharacterised BCR, COG1649
NCG97_RS30665	COG0697	spore germination
NCG97_RS30705	COG4106	trans-aconitate 2-methyltransferase activity
NCG97_RS30715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NCG97_RS30725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NCG97_RS30735	COG1438	arginine binding
NCG97_RS30740	COG0668	transmembrane transport
NCG97_RS30745	COG1720	tRNA m6t6A37 methyltransferase activity
NCG97_RS30765	COG0165	Argininosuccinate lyase
NCG97_RS30775	COG0477	Major facilitator Superfamily
NCG97_RS30785	COG0204	Acyl-transferase
NCG97_RS30785	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS30790	COG0584	glycerophosphoryl diester phosphodiesterase
NCG97_RS30815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NCG97_RS30820	COG2011	ABC-type metal ion transport system permease component
NCG97_RS30825	COG1464	Belongs to the NlpA lipoprotein family
NCG97_RS30900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NCG97_RS30960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NCG97_RS30975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NCG97_RS31015	COG1560	Kdo2-lipid A biosynthetic process
NCG97_RS31030	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NCG97_RS31035	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NCG97_RS31040	COG0217	transcriptional regulatory protein
NCG97_RS31045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NCG97_RS31050	COG0632	four-way junction helicase activity
NCG97_RS31055	COG2255	four-way junction helicase activity
NCG97_RS31065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NCG97_RS31070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NCG97_RS31075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NCG97_RS31080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NCG97_RS31100	COG0124	histidyl-tRNA synthetase
NCG97_RS31120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NCG97_RS31155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NCG97_RS31160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NCG97_RS31170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NCG97_RS31175	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NCG97_RS31185	COG0006	proline dipeptidase activity
NCG97_RS31190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NCG97_RS31195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NCG97_RS31205	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NCG97_RS31210	COG0540	Belongs to the ATCase OTCase family
NCG97_RS31215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NCG97_RS31225	COG0505	Belongs to the CarA family
NCG97_RS31235	COG0167	dihydroorotate dehydrogenase activity
NCG97_RS31240	COG0284	orotidine-5'-phosphate decarboxylase activity
NCG97_RS31265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NCG97_RS31280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NCG97_RS31290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NCG97_RS31315	COG0531	amino acid
NCG97_RS31345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NCG97_RS31370	COG1335	isochorismatase
NCG97_RS31380	COG2223	nitrite transmembrane transporter activity
NCG97_RS31390	COG1090	epimerase
NCG97_RS31405	COG3201	nicotinamide mononucleotide transporter
NCG97_RS31410	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NCG97_RS31410	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NCG97_RS31415	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NCG97_RS31420	COG0140	phosphoribosyl-ATP diphosphatase activity
NCG97_RS31425	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NCG97_RS31465	COG0667	Aldo Keto reductase
NCG97_RS31470	COG0589	response to stress
NCG97_RS31475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NCG97_RS31495	COG0583	DNA-binding transcription factor activity
NCG97_RS31505	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS31510	COG0583	DNA-binding transcription factor activity
NCG97_RS31610	COG3903	Transcriptional regulator
NCG97_RS31610	COG3629	intracellular signal transduction
NCG97_RS31615	COG3903	Transcriptional regulator
NCG97_RS31615	COG3629	intracellular signal transduction
NCG97_RS31625	COG1222	aaa ATPase
NCG97_RS31635	COG2197	response regulator
NCG97_RS31665	COG2838	Isocitrate dehydrogenase
NCG97_RS31680	COG0671	phosphoesterase, PA-phosphatase related
NCG97_RS31710	COG0765	amino acid transport
NCG97_RS31720	COG0584	glycerophosphoryl diester phosphodiesterase
NCG97_RS31770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NCG97_RS31775	COG2318	DinB family
NCG97_RS31785	COG1309	transcriptional regulator
NCG97_RS31815	COG3345	alpha-galactosidase
NCG97_RS31825	COG1175	transmembrane transport
NCG97_RS31830	COG0395	ABC-type sugar transport system, permease component
NCG97_RS31845	COG0445	tRNA wobble uridine modification
NCG97_RS31855	COG2197	response regulator
NCG97_RS31865	COG2223	nitrite transmembrane transporter activity
NCG97_RS31870	COG1940	carbohydrate kinase activity
NCG97_RS31920	COG1349	DNA-binding transcription factor activity
NCG97_RS31950	COG0633	Ferredoxin
NCG97_RS31950	COG3217	Mosc domain protein beta barrel domain protein
NCG97_RS31965	COG0463	Glycosyl transferase, family 2
NCG97_RS31970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NCG97_RS31990	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS32080	COG0647	UMP catabolic process
NCG97_RS32085	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NCG97_RS32100	COG0590	tRNA wobble adenosine to inosine editing
NCG97_RS32105	COG3224	Antibiotic biosynthesis monooxygenase
NCG97_RS32135	COG0789	Transcriptional regulator
NCG97_RS32155	COG0395	ABC-type sugar transport system, permease component
NCG97_RS32200	COG1461	Dihydroxyacetone kinase
NCG97_RS32210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NCG97_RS32290	COG0783	Belongs to the Dps family
NCG97_RS32325	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NCG97_RS32345	COG1793	dna ligase
NCG97_RS32345	COG3285	dna ligase
NCG97_RS32360	COG1007	ATP synthesis coupled electron transport
NCG97_RS32365	COG1006	Multisubunit Na H antiporter MnhC subunit
NCG97_RS32390	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NCG97_RS32405	COG0243	molybdopterin cofactor binding
NCG97_RS32425	COG2814	Major facilitator Superfamily
NCG97_RS32435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NCG97_RS32440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NCG97_RS32445	COG1120	ATPase activity
NCG97_RS32455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NCG97_RS32475	COG1960	acyl-CoA dehydrogenase activity
NCG97_RS32485	COG0515	serine threonine protein kinase
NCG97_RS32500	COG2070	2-Nitropropane dioxygenase
NCG97_RS32510	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS32530	COG1605	Chorismate mutase
NCG97_RS32645	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NCG97_RS32665	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NCG97_RS32690	COG1414	Transcriptional regulator
NCG97_RS32695	COG2146	nitrite reductase [NAD(P)H] activity
NCG97_RS32745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NCG97_RS32750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NCG97_RS32770	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NCG97_RS32775	COG1176	ABC-type spermidine putrescine transport system, permease component I
NCG97_RS32780	COG1177	transmembrane transport
NCG97_RS32785	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NCG97_RS32805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NCG97_RS32835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NCG97_RS32855	COG1716	ATPase activity
NCG97_RS32875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NCG97_RS32960	COG0697	spore germination
NCG97_RS32965	COG0583	DNA-binding transcription factor activity
NCG97_RS32975	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS33020	COG0738	Major facilitator superfamily
NCG97_RS33065	COG1280	lysine exporter protein (LysE YggA)
NCG97_RS33075	COG2233	PERMEase
NCG97_RS33080	COG0402	S-adenosylhomocysteine deaminase activity
NCG97_RS33095	COG3548	integral membrane protein
NCG97_RS33145	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS33150	COG2197	response regulator
NCG97_RS33170	COG2197	response regulator
NCG97_RS33195	COG0604	alcohol dehydrogenase
NCG97_RS33195	COG3321	synthase
NCG97_RS33220	COG0604	alcohol dehydrogenase
NCG97_RS33220	COG3321	synthase
NCG97_RS33235	COG3321	synthase
NCG97_RS33235	COG0604	alcohol dehydrogenase
NCG97_RS33240	COG0604	alcohol dehydrogenase
NCG97_RS33240	COG3321	synthase
NCG97_RS33250	COG0604	alcohol dehydrogenase
NCG97_RS33250	COG3321	synthase
NCG97_RS33270	COG0604	alcohol dehydrogenase
NCG97_RS33270	COG3321	synthase
NCG97_RS33285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NCG97_RS33330	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NCG97_RS33385	COG4585	Histidine kinase
NCG97_RS33390	COG2197	response regulator
NCG97_RS33415	COG4221	oxidoreductase activity
NCG97_RS33435	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS33480	COG1191	sigma factor activity
NCG97_RS33555	COG0667	Aldo Keto reductase
NCG97_RS33560	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NCG97_RS33585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NCG97_RS33595	COG1132	(ABC) transporter
NCG97_RS33610	COG0386	Belongs to the glutathione peroxidase family
NCG97_RS33645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NCG97_RS33690	COG0640	Transcriptional regulator
NCG97_RS33715	COG0438	transferase activity, transferring glycosyl groups
NCG97_RS33730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NCG97_RS33730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NCG97_RS33740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NCG97_RS33770	COG2015	COG2015, Alkyl sulfatase and related hydrolases
NCG97_RS33830	COG3585	molybdate ion transport
NCG97_RS33875	COG2814	Major facilitator Superfamily
NCG97_RS33900	COG0745	RESPONSE REGULATOR receiver
NCG97_RS33920	COG2318	DinB family
NCG97_RS33950	COG1063	alcohol dehydrogenase
NCG97_RS33955	COG0156	8-amino-7-oxononanoate synthase activity
NCG97_RS33960	COG0583	DNA-binding transcription factor activity
NCG97_RS33975	COG1796	DNA polymerase
NCG97_RS33975	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NCG97_RS33990	COG2274	protein secretion by the type I secretion system
NCG97_RS34110	COG2423	ornithine cyclodeaminase activity
NCG97_RS34120	COG0626	cystathionine gamma-synthase activity
NCG97_RS34125	COG3135	benzoate transporter
NCG97_RS34165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NCG97_RS34175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NCG97_RS34185	COG1414	Transcriptional regulator
NCG97_RS34200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NCG97_RS34215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NCG97_RS34235	COG1595	DNA-templated transcription, initiation
NCG97_RS34245	COG2186	Transcriptional regulator
NCG97_RS34250	COG1620	l-lactate permease
NCG97_RS34255	COG0247	lactate metabolic process
NCG97_RS34265	COG1556	Lactate utilization protein
NCG97_RS34290	COG2186	Transcriptional regulator
NCG97_RS34300	COG4565	transcriptional regulatory protein
NCG97_RS34315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NCG97_RS34360	COG1864	DNA RNA non-specific endonuclease
NCG97_RS34360	COG3591	Belongs to the peptidase S1B family
NCG97_RS34380	COG0542	response to heat
NCG97_RS34395	COG0542	response to heat
NCG97_RS34430	COG0183	Belongs to the thiolase family
NCG97_RS34450	COG1024	Enoyl-CoA hydratase
NCG97_RS34480	COG1802	Transcriptional regulator
NCG97_RS34485	COG0006	proline dipeptidase activity
NCG97_RS34505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NCG97_RS34530	COG2326	polyphosphate kinase activity
NCG97_RS34560	COG4213	ABC transporter substrate-binding protein
NCG97_RS34630	COG1113	amino acid transport
NCG97_RS34680	COG0179	Fumarylacetoacetate (FAA) hydrolase
NCG97_RS34685	COG1414	Transcriptional regulator
NCG97_RS34690	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NCG97_RS34735	COG0515	serine threonine protein kinase
NCG97_RS34745	COG1132	(ABC) transporter
NCG97_RS34755	COG2197	response regulator
NCG97_RS34815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NCG97_RS34820	COG0443	Heat shock 70 kDa protein
NCG97_RS34825	COG3424	synthase
NCG97_RS34835	COG4221	oxidoreductase activity
NCG97_RS34855	COG0513	Belongs to the DEAD box helicase family
NCG97_RS34860	COG1278	Cold shock
NCG97_RS34870	COG0517	IMP dehydrogenase activity
NCG97_RS34870	COG0516	GMP reductase activity
NCG97_RS34885	COG0517	IMP dehydrogenase activity
NCG97_RS34885	COG0516	GMP reductase activity
NCG97_RS34940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NCG97_RS34960	COG1121	(ABC) transporter
NCG97_RS34975	COG0384	phenazine biosynthesis protein PhzF
NCG97_RS34995	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NCG97_RS35130	COG1129	ABC transporter
NCG97_RS35145	COG0277	FAD linked oxidase domain protein
NCG97_RS35230	COG1573	uracil-dna glycosylase
NCG97_RS35260	COG0494	nUDIX hydrolase
NCG97_RS35340	COG3655	Transcriptional regulator
NCG97_RS35365	COG1132	(ABC) transporter
NCG97_RS35370	COG0583	DNA-binding transcription factor activity
NCG97_RS35410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NCG97_RS35410	COG0515	serine threonine protein kinase
NCG97_RS35430	COG0542	response to heat
NCG97_RS35445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NCG97_RS35465	COG1366	Belongs to the anti-sigma-factor antagonist family
NCG97_RS35470	COG1366	Belongs to the anti-sigma-factor antagonist family
NCG97_RS35475	COG2172	sigma factor antagonist activity
NCG97_RS35525	COG1819	glycosyl
NCG97_RS35540	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NCG97_RS35550	COG0515	serine threonine protein kinase
NCG97_RS35575	COG0626	cystathionine gamma-synthase activity
NCG97_RS35585	COG2814	Major facilitator Superfamily
NCG97_RS35615	COG1028	Short-chain dehydrogenase reductase Sdr
NCG97_RS35625	COG3227	Zinc metalloprotease (Elastase)
NCG97_RS35635	COG0513	Belongs to the DEAD box helicase family
NCG97_RS35675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NCG97_RS35730	COG1794	racemase activity, acting on amino acids and derivatives
NCG97_RS35750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NCG97_RS35780	COG0181	hydroxymethylbilane synthase activity
NCG97_RS35785	COG0583	DNA-binding transcription factor activity
NCG97_RS35815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NCG97_RS35840	COG4977	sequence-specific DNA binding
NCG97_RS35865	COG3387	PFAM Glycoside hydrolase 15-related
NCG97_RS35885	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NCG97_RS35975	COG1022	Amp-dependent synthetase and ligase
NCG97_RS35995	COG0402	S-adenosylhomocysteine deaminase activity
NCG97_RS36050	COG1113	amino acid transport
NCG97_RS36055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NCG97_RS36070	COG1271	oxidase subunit
NCG97_RS36105	COG2226	methyltransferase
NCG97_RS36110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NCG97_RS36140	COG2814	Major facilitator Superfamily
NCG97_RS36145	COG1063	alcohol dehydrogenase
NCG97_RS36150	COG1349	DNA-binding transcription factor activity
NCG97_RS36170	COG0395	ABC-type sugar transport system, permease component
NCG97_RS36175	COG1175	transmembrane transport
NCG97_RS36180	COG1653	transport
NCG97_RS36185	COG0366	Alpha amylase catalytic
NCG97_RS36190	COG1653	transport
NCG97_RS36200	COG1136	(ABC) transporter
NCG97_RS36200	COG0577	efflux transmembrane transporter activity
NCG97_RS36210	COG2340	Cysteine-rich secretory protein family
NCG97_RS36245	COG3647	Membrane
NCG97_RS36290	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NCG97_RS36300	COG0009	L-threonylcarbamoyladenylate synthase
NCG97_RS36335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NCG97_RS36340	COG4948	Mandelate Racemase Muconate Lactonizing
NCG97_RS36355	COG4533	DNA binding
NCG97_RS36360	COG0601	transmembrane transport
NCG97_RS36365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NCG97_RS36370	COG4172	Belongs to the ABC transporter superfamily
NCG97_RS36415	COG0529	Catalyzes the synthesis of activated sulfate
NCG97_RS36435	COG2364	Membrane
NCG97_RS36440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NCG97_RS36450	COG0405	Gamma-glutamyltransferase
NCG97_RS36460	COG0454	-acetyltransferase
NCG97_RS36515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCG97_RS36615	COG1280	lysine exporter protein (LysE YggA)
NCG97_RS36740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NCG97_RS36770	COG0302	gtp cyclohydrolase
NCG97_RS36795	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NCG97_RS36835	COG2890	protein-(glutamine-N5) methyltransferase activity
NCG97_RS36895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NCG97_RS36935	COG1051	belongs to the nudix hydrolase family
NCG97_RS36955	COG2197	response regulator
NCG97_RS36975	COG4585	Histidine kinase
NCG97_RS37015	COG0318	PFAM AMP-dependent synthetase and ligase
NCG97_RS37100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics