locus-tag	class	description
SL103_RS00010	COG0592	DNA-directed DNA polymerase activity
SL103_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SL103_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SL103_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SL103_RS00030	COG0187	DNA topoisomerase II activity
SL103_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SL103_RS00060	COG0515	serine threonine protein kinase
SL103_RS00085	COG0705	Rhomboid family
SL103_RS00100	COG3764	Sortase (surface protein transpeptidase)
SL103_RS00110	COG3764	Sortase (surface protein transpeptidase)
SL103_RS00115	COG3764	Sortase (surface protein transpeptidase)
SL103_RS00120	COG0515	serine threonine protein kinase
SL103_RS00130	COG0772	Belongs to the SEDS family
SL103_RS00140	COG1716	ATPase activity
SL103_RS00145	COG1716	ATPase activity
SL103_RS00155	COG0583	DNA-binding transcription factor activity
SL103_RS00160	COG2814	Major facilitator Superfamily
SL103_RS00165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SL103_RS00170	COG1733	regulation of RNA biosynthetic process
SL103_RS00205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SL103_RS00210	COG2151	metal-sulfur cluster biosynthetic enzyme
SL103_RS00215	COG3396	Phenylacetate-CoA oxygenase
SL103_RS00220	COG3460	Phenylacetate-CoA oxygenase
SL103_RS00225	COG3396	Phenylacetate-CoA oxygenase
SL103_RS00250	COG1250	3-hydroxyacyl-CoA dehydrogenase
SL103_RS00255	COG1309	transcriptional regulator
SL103_RS00260	COG1522	sequence-specific DNA binding
SL103_RS00290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SL103_RS00310	COG0515	serine threonine protein kinase
SL103_RS00340	COG0022	dehydrogenase e1 component
SL103_RS00345	COG0508	dehydrogenase complex catalyzes the overall conversion of
SL103_RS00350	COG0494	nUDIX hydrolase
SL103_RS00360	COG2814	Major facilitator Superfamily
SL103_RS00400	COG3629	intracellular signal transduction
SL103_RS00400	COG3903	Transcriptional regulator
SL103_RS00405	COG1362	aminopeptidase activity
SL103_RS00410	COG1960	acyl-CoA dehydrogenase activity
SL103_RS00435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SL103_RS00445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SL103_RS00475	COG1174	glycine betaine transport
SL103_RS00480	COG1174	glycine betaine transport
SL103_RS00490	COG0517	IMP dehydrogenase activity
SL103_RS00490	COG1125	glycine betaine transport
SL103_RS00495	COG0745	RESPONSE REGULATOR receiver
SL103_RS00535	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SL103_RS00600	COG1316	TRANSCRIPTIONal
SL103_RS00640	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS00645	COG2030	dehydratase
SL103_RS00650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SL103_RS00655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SL103_RS00700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SL103_RS00710	COG0515	serine threonine protein kinase
SL103_RS00720	COG2197	response regulator
SL103_RS00725	COG4585	Histidine kinase
SL103_RS00735	COG1652	LysM domain
SL103_RS00745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SL103_RS00750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SL103_RS00790	COG0515	serine threonine protein kinase
SL103_RS00800	COG2205	protein histidine kinase activity
SL103_RS00830	COG2197	response regulator
SL103_RS00890	COG1674	ftsk spoiiie
SL103_RS00950	COG0163	prenyltransferase activity
SL103_RS00965	COG0717	Belongs to the dCTP deaminase family
SL103_RS00970	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SL103_RS00990	COG0247	lactate metabolic process
SL103_RS00990	COG2181	nitrate reductase activity
SL103_RS00995	COG0443	Heat shock 70 kDa protein
SL103_RS01000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SL103_RS01005	COG0484	heat shock protein binding
SL103_RS01010	COG0789	Transcriptional regulator
SL103_RS01030	COG0542	response to heat
SL103_RS01055	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SL103_RS01070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SL103_RS01075	COG0191	fructose-bisphosphate aldolase activity
SL103_RS01080	COG0477	Major facilitator Superfamily
SL103_RS01090	COG3483	tryptophan 2,3-dioxygenase activity
SL103_RS01095	COG3844	kynureninase activity
SL103_RS01105	COG4585	Histidine kinase
SL103_RS01110	COG2197	response regulator
SL103_RS01115	COG3559	Exporter of polyketide antibiotics
SL103_RS01120	COG1131	(ABC) transporter
SL103_RS01135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SL103_RS01145	COG0515	serine threonine protein kinase
SL103_RS01145	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SL103_RS01155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SL103_RS01160	COG1802	Transcriptional regulator
SL103_RS01175	COG0151	Belongs to the GarS family
SL103_RS01190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SL103_RS01200	COG2197	response regulator
SL103_RS01215	COG1131	(ABC) transporter
SL103_RS01235	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SL103_RS01240	COG0047	phosphoribosylformylglycinamidine synthase activity
SL103_RS01245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SL103_RS01260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SL103_RS01295	COG1643	Atp-dependent helicase
SL103_RS01335	COG0513	Belongs to the DEAD box helicase family
SL103_RS01360	COG0667	Aldo Keto reductase
SL103_RS01380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SL103_RS01385	COG0579	oxidoreductase
SL103_RS01425	COG1846	Transcriptional regulator
SL103_RS01450	COG2223	nitrite transmembrane transporter activity
SL103_RS01455	COG0123	including yeast histone deacetylase and acetoin utilization protein
SL103_RS01500	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SL103_RS01505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SL103_RS01510	COG0181	hydroxymethylbilane synthase activity
SL103_RS01515	COG1648	precorrin-2 dehydrogenase activity
SL103_RS01515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SL103_RS01520	COG0113	porphobilinogen synthase activity
SL103_RS01525	COG3237	CsbD-like
SL103_RS01530	COG0018	arginyl-trna synthetase
SL103_RS01535	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SL103_RS01555	COG1690	Belongs to the RtcB family
SL103_RS01570	COG1742	UPF0060 membrane protein
SL103_RS01580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SL103_RS01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SL103_RS01615	COG0406	alpha-ribazole phosphatase activity
SL103_RS01635	COG1333	cytochrome c biogenesis protein
SL103_RS01640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SL103_RS01665	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SL103_RS01670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SL103_RS01680	COG0163	prenyltransferase activity
SL103_RS01690	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SL103_RS01705	COG1301	dicarboxylic acid transport
SL103_RS01720	COG0640	Transcriptional regulator
SL103_RS01725	COG0798	PFAM Bile acid sodium symporter
SL103_RS01730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SL103_RS01745	COG1309	transcriptional regulator
SL103_RS01785	COG1278	Cold shock
SL103_RS01790	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SL103_RS01795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SL103_RS01805	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SL103_RS01815	COG2226	methyltransferase
SL103_RS01850	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SL103_RS01855	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SL103_RS01860	COG0649	NAD binding
SL103_RS01870	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SL103_RS01875	COG1034	ATP synthesis coupled electron transport
SL103_RS01880	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SL103_RS01885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SL103_RS01890	COG0839	Belongs to the complex I subunit 6 family
SL103_RS01895	COG0713	ATP synthesis coupled electron transport
SL103_RS01900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SL103_RS01910	COG1007	ATP synthesis coupled electron transport
SL103_RS01940	COG0142	geranyltranstransferase activity
SL103_RS01950	COG1131	(ABC) transporter
SL103_RS01965	COG0702	epimerase
SL103_RS01970	COG1013	pyruvate-flavodoxin oxidoreductase activity
SL103_RS01975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SL103_RS01975	COG0674	pyruvate-flavodoxin oxidoreductase activity
SL103_RS01985	COG4585	Histidine kinase
SL103_RS01990	COG4585	Histidine kinase
SL103_RS02005	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SL103_RS02010	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SL103_RS02015	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SL103_RS02020	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SL103_RS02025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SL103_RS02030	COG0839	Belongs to the complex I subunit 6 family
SL103_RS02035	COG0713	ATP synthesis coupled electron transport
SL103_RS02040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SL103_RS02050	COG1007	ATP synthesis coupled electron transport
SL103_RS02055	COG0501	Belongs to the peptidase M48B family
SL103_RS02060	COG3304	Inner membrane component domain
SL103_RS02070	COG1666	GTP binding
SL103_RS02080	COG0702	epimerase
SL103_RS02085	COG0402	S-adenosylhomocysteine deaminase activity
SL103_RS02100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SL103_RS02105	COG2030	dehydratase
SL103_RS02115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SL103_RS02120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SL103_RS02125	COG0436	Aminotransferase
SL103_RS02140	COG0250	Participates in transcription elongation, termination and antitermination
SL103_RS02145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SL103_RS02150	COG0081	regulation of translation
SL103_RS02160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SL103_RS02165	COG0222	ribosome binding
SL103_RS02170	COG0085	RNA polymerase activity
SL103_RS02175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SL103_RS02185	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SL103_RS02190	COG0049	tRNA binding
SL103_RS02195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SL103_RS02200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SL103_RS02205	COG0051	transcription antitermination factor activity, RNA binding
SL103_RS02210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SL103_RS02215	COG0088	Forms part of the polypeptide exit tunnel
SL103_RS02220	COG0089	rRNA binding
SL103_RS02225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SL103_RS02230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SL103_RS02235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SL103_RS02240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SL103_RS02245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SL103_RS02250	COG0255	Belongs to the universal ribosomal protein uL29 family
SL103_RS02255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SL103_RS02260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SL103_RS02265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SL103_RS02270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SL103_RS02275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SL103_RS02280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SL103_RS02285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SL103_RS02290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SL103_RS02295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SL103_RS02300	COG1841	ribosomal large subunit assembly
SL103_RS02305	COG0200	Binds to the 23S rRNA
SL103_RS02315	COG0563	adenylate kinase activity
SL103_RS02325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SL103_RS02330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SL103_RS02335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SL103_RS02340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SL103_RS02345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SL103_RS02350	COG0202	RNA polymerase activity
SL103_RS02355	COG0203	ribosomal protein L17
SL103_RS02360	COG0101	tRNA pseudouridine synthase activity
SL103_RS02370	COG0488	(ABC) transporter
SL103_RS02375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SL103_RS02380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SL103_RS02385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SL103_RS02395	COG1072	(Pantothenic acid kinase))
SL103_RS02405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SL103_RS02410	COG0736	holo-[acyl-carrier-protein] synthase activity
SL103_RS02420	COG1376	ErfK ybiS ycfS ynhG family protein
SL103_RS02425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SL103_RS02435	COG0802	atpase or kinase
SL103_RS02460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SL103_RS02475	COG0772	Belongs to the SEDS family
SL103_RS02480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SL103_RS02500	COG4221	oxidoreductase activity
SL103_RS02510	COG0583	DNA-binding transcription factor activity
SL103_RS02525	COG1595	DNA-templated transcription, initiation
SL103_RS02535	COG0516	GMP reductase activity
SL103_RS02580	COG1960	acyl-CoA dehydrogenase activity
SL103_RS02585	COG1960	acyl-CoA dehydrogenase activity
SL103_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS02605	COG1960	acyl-CoA dehydrogenase activity
SL103_RS02620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SL103_RS02635	COG1024	Enoyl-CoA hydratase
SL103_RS02685	COG1960	acyl-CoA dehydrogenase activity
SL103_RS02695	COG1309	transcriptional regulator
SL103_RS02700	COG0515	serine threonine protein kinase
SL103_RS02700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SL103_RS02715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SL103_RS02780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS02795	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SL103_RS02830	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SL103_RS02845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SL103_RS02860	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS02865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SL103_RS02890	COG1686	Belongs to the peptidase S11 family
SL103_RS02910	COG0514	ATP-dependent DNA helicase (RecQ)
SL103_RS02930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SL103_RS02935	COG0604	alcohol dehydrogenase
SL103_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS02935	COG3321	synthase
SL103_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS02980	COG3387	PFAM Glycoside hydrolase 15-related
SL103_RS03050	COG3629	intracellular signal transduction
SL103_RS03050	COG3903	Transcriptional regulator
SL103_RS03060	COG0189	ligase activity
SL103_RS03075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SL103_RS03080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SL103_RS03085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SL103_RS03090	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SL103_RS03140	COG1309	transcriptional regulator
SL103_RS03160	COG1846	Transcriptional regulator
SL103_RS03165	COG3384	dioxygenase
SL103_RS03180	COG1247	-acetyltransferase
SL103_RS03190	COG1349	DNA-binding transcription factor activity
SL103_RS03195	COG1105	Belongs to the carbohydrate kinase PfkB family
SL103_RS03200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SL103_RS03200	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SL103_RS03200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SL103_RS03225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SL103_RS03280	COG0730	response to heat
SL103_RS03285	COG2188	Transcriptional regulator
SL103_RS03290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SL103_RS03295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SL103_RS03310	COG1970	mechanosensitive ion channel activity
SL103_RS03315	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SL103_RS03330	COG3263	regulation of cellular component size
SL103_RS03340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SL103_RS03345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SL103_RS03355	COG0315	cyclic pyranopterin monophosphate synthase activity
SL103_RS03360	COG0315	cyclic pyranopterin monophosphate synthase activity
SL103_RS03360	COG0521	Mo-molybdopterin cofactor biosynthetic process
SL103_RS03365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SL103_RS03400	COG0789	Transcriptional regulator
SL103_RS03405	COG1725	Transcriptional regulator
SL103_RS03425	COG0708	Exodeoxyribonuclease III
SL103_RS03435	COG3629	intracellular signal transduction
SL103_RS03435	COG3903	Transcriptional regulator
SL103_RS03445	COG2072	flavoprotein involved in K transport
SL103_RS03450	COG2267	carboxylic ester hydrolase activity
SL103_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS03465	COG0793	Belongs to the peptidase S41A family
SL103_RS03465	COG4946	Tricorn protease homolog
SL103_RS03475	COG0310	cobalt ion transport
SL103_RS03485	COG1122	ATPase activity
SL103_RS03525	COG0084	hydrolase, TatD family'
SL103_RS03535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SL103_RS03540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SL103_RS03545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SL103_RS03560	COG0488	(ABC) transporter
SL103_RS03565	COG3209	COG3209 Rhs family protein
SL103_RS03605	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SL103_RS03610	COG2197	response regulator
SL103_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS03630	COG4106	trans-aconitate 2-methyltransferase activity
SL103_RS03640	COG1309	transcriptional regulator
SL103_RS03650	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SL103_RS03660	COG0193	aminoacyl-tRNA hydrolase activity
SL103_RS03665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SL103_RS03670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SL103_RS03675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SL103_RS03685	COG4585	Histidine kinase
SL103_RS03710	COG1316	TRANSCRIPTIONal
SL103_RS03720	COG2814	Major facilitator Superfamily
SL103_RS03750	COG0515	serine threonine protein kinase
SL103_RS03750	COG2815	serine threonine protein kinase
SL103_RS03755	COG2318	DinB family
SL103_RS03775	COG2814	Major facilitator Superfamily
SL103_RS03780	COG0583	DNA-binding transcription factor activity
SL103_RS03785	COG2124	cytochrome p450
SL103_RS03800	COG0148	phosphopyruvate hydratase activity
SL103_RS03835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SL103_RS03840	COG0577	efflux transmembrane transporter activity
SL103_RS03845	COG0577	efflux transmembrane transporter activity
SL103_RS03845	COG1136	(ABC) transporter
SL103_RS03860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SL103_RS03885	COG0183	Belongs to the thiolase family
SL103_RS03890	COG2755	lipolytic protein G-D-S-L family
SL103_RS03905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SL103_RS03920	COG1609	Transcriptional regulator
SL103_RS03935	COG1174	glycine betaine transport
SL103_RS03940	COG1174	glycine betaine transport
SL103_RS03950	COG2986	histidine ammonia-lyase
SL103_RS03960	COG0019	diaminopimelate decarboxylase activity
SL103_RS03970	COG1131	(ABC) transporter
SL103_RS03985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SL103_RS04000	COG1228	amidohydrolase
SL103_RS04005	COG1191	sigma factor activity
SL103_RS04010	COG1366	Belongs to the anti-sigma-factor antagonist family
SL103_RS04040	COG3104	oligopeptide transport
SL103_RS04045	COG0745	RESPONSE REGULATOR receiver
SL103_RS04050	COG2205	protein histidine kinase activity
SL103_RS04090	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SL103_RS04100	COG1316	TRANSCRIPTIONal
SL103_RS04120	COG1316	TRANSCRIPTIONal
SL103_RS04165	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SL103_RS04165	COG0778	Nitroreductase
SL103_RS04170	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SL103_RS04205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SL103_RS04210	COG2835	tetraacyldisaccharide 4'-kinase activity
SL103_RS04220	COG1482	cell wall glycoprotein biosynthetic process
SL103_RS04230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SL103_RS04230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SL103_RS04230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SL103_RS04235	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SL103_RS04280	COG0714	Associated with various cellular activities
SL103_RS04300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SL103_RS04305	COG0745	RESPONSE REGULATOR receiver
SL103_RS04310	COG5002	protein histidine kinase activity
SL103_RS04315	COG0823	Involved in the tonB-independent uptake of proteins
SL103_RS04325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SL103_RS04330	COG2197	response regulator
SL103_RS04345	COG0653	protein targeting
SL103_RS04365	COG2902	Dehydrogenase
SL103_RS04370	COG1134	teichoic acid transport
SL103_RS04380	COG1309	transcriptional regulator
SL103_RS04385	COG0463	Glycosyl transferase, family 2
SL103_RS04385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SL103_RS04400	COG0463	Glycosyl transferase, family 2
SL103_RS04425	COG1215	transferase activity, transferring glycosyl groups
SL103_RS04425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SL103_RS04430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SL103_RS04445	COG0395	ABC-type sugar transport system, permease component
SL103_RS04450	COG1175	transmembrane transport
SL103_RS04455	COG1653	transport
SL103_RS04465	COG0515	serine threonine protein kinase
SL103_RS04470	COG0515	serine threonine protein kinase
SL103_RS04475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SL103_RS04490	COG2884	Cell division ATP-binding protein ftsE
SL103_RS04495	COG2177	Part of the ABC transporter FtsEX involved in
SL103_RS04500	COG0793	Belongs to the peptidase S41A family
SL103_RS04505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SL103_RS04520	COG0583	DNA-binding transcription factor activity
SL103_RS04535	COG2223	nitrite transmembrane transporter activity
SL103_RS04565	COG3973	AAA domain
SL103_RS04575	COG0776	regulation of translation
SL103_RS04580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SL103_RS04585	COG1678	Uncharacterized ACR, COG1678
SL103_RS04605	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SL103_RS04620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SL103_RS04635	COG0477	Major facilitator Superfamily
SL103_RS04660	COG1174	glycine betaine transport
SL103_RS04670	COG1174	glycine betaine transport
SL103_RS04680	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SL103_RS04685	COG0277	FAD linked oxidase domain protein
SL103_RS04695	COG0222	ribosome binding
SL103_RS04700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SL103_RS04740	COG1335	isochorismatase
SL103_RS04750	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SL103_RS04760	COG1113	amino acid transport
SL103_RS04780	COG1234	tRNA 3'-trailer cleavage
SL103_RS04785	COG1263	PTS System
SL103_RS04790	COG1263	PTS System
SL103_RS04795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SL103_RS04800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SL103_RS04810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SL103_RS04840	COG2205	protein histidine kinase activity
SL103_RS04855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SL103_RS04865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SL103_RS04895	COG2733	membrane
SL103_RS04900	COG3764	Sortase (surface protein transpeptidase)
SL103_RS04910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SL103_RS05010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SL103_RS05080	COG0706	membrane insertase activity
SL103_RS05085	COG0179	Fumarylacetoacetate (FAA) hydrolase
SL103_RS05090	COG0673	inositol 2-dehydrogenase activity
SL103_RS05150	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS05180	COG1126	abc transporter atp-binding protein
SL103_RS05185	COG0765	amino acid transport
SL103_RS05190	COG0765	amino acid transport
SL103_RS05205	COG0154	amidase activity
SL103_RS05210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SL103_RS05225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS05285	COG0492	ferredoxin-NADP+ reductase activity
SL103_RS05300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SL103_RS05335	COG3979	chitinase
SL103_RS05355	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SL103_RS05360	COG4977	sequence-specific DNA binding
SL103_RS05370	COG0589	response to stress
SL103_RS05375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SL103_RS05390	COG1960	acyl-CoA dehydrogenase activity
SL103_RS05405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SL103_RS05410	COG1309	transcriptional regulator
SL103_RS05420	COG1946	Acyl-CoA thioesterase
SL103_RS05465	COG0028	Belongs to the TPP enzyme family
SL103_RS05470	COG1309	transcriptional regulator
SL103_RS05480	COG0842	Transport permease protein
SL103_RS05480	COG1129	ABC transporter
SL103_RS05485	COG1554	hydrolase, family 65, central catalytic
SL103_RS05500	COG1472	Belongs to the glycosyl hydrolase 3 family
SL103_RS05510	COG1846	Transcriptional regulator
SL103_RS05510	COG0456	acetyltransferase
SL103_RS05515	COG1609	Transcriptional regulator
SL103_RS05520	COG0673	inositol 2-dehydrogenase activity
SL103_RS05535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SL103_RS05545	COG2608	mercury ion transmembrane transporter activity
SL103_RS05555	COG0673	inositol 2-dehydrogenase activity
SL103_RS05560	COG1609	Transcriptional regulator
SL103_RS05565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SL103_RS05580	COG2814	Major facilitator Superfamily
SL103_RS05585	COG0673	inositol 2-dehydrogenase activity
SL103_RS05595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SL103_RS05605	COG3718	enzyme involved in inositol metabolism
SL103_RS05610	COG3962	Belongs to the TPP enzyme family
SL103_RS05630	COG1131	(ABC) transporter
SL103_RS05640	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SL103_RS05655	COG0596	Alpha beta hydrolase
SL103_RS05665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SL103_RS05685	COG2326	polyphosphate kinase activity
SL103_RS05690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SL103_RS05710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SL103_RS05715	COG0629	single-stranded DNA binding
SL103_RS05740	COG1136	(ABC) transporter
SL103_RS05740	COG0577	efflux transmembrane transporter activity
SL103_RS05755	COG2346	COG2346, Truncated hemoglobins
SL103_RS05780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SL103_RS05790	COG2186	Transcriptional regulator
SL103_RS05805	COG1486	melibiose metabolic process
SL103_RS05810	COG0395	ABC-type sugar transport system, permease component
SL103_RS05815	COG1175	transmembrane transport
SL103_RS05825	COG1846	Transcriptional regulator
SL103_RS05825	COG1940	carbohydrate kinase activity
SL103_RS05830	COG0668	transmembrane transport
SL103_RS05880	COG4266	Belongs to the allantoicase family
SL103_RS05915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SL103_RS05920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SL103_RS05925	COG1113	amino acid transport
SL103_RS05930	COG1113	amino acid transport
SL103_RS05940	COG1113	amino acid transport
SL103_RS05945	COG0698	ribose 5-phosphate isomerase
SL103_RS05955	COG4552	Acetyltransferase involved in intracellular survival and related
SL103_RS05965	COG3594	Acyltransferase
SL103_RS05990	COG0544	peptidyl-prolyl cis-trans isomerase activity
SL103_RS05995	COG0740	serine-type endopeptidase activity
SL103_RS06000	COG0740	serine-type endopeptidase activity
SL103_RS06005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SL103_RS06015	COG0525	valine-tRNA ligase activity
SL103_RS06025	COG0768	penicillin binding
SL103_RS06030	COG0285	dihydrofolate synthase activity
SL103_RS06040	COG0105	UTP biosynthetic process
SL103_RS06045	COG1077	Cell shape determining protein MreB Mrl
SL103_RS06060	COG0768	penicillin binding
SL103_RS06065	COG0772	Belongs to the SEDS family
SL103_RS06100	COG1530	ribonuclease E activity
SL103_RS06105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SL103_RS06110	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SL103_RS06115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SL103_RS06125	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SL103_RS06135	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SL103_RS06150	COG0501	Belongs to the peptidase M48B family
SL103_RS06155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SL103_RS06165	COG0799	negative regulation of ribosome biogenesis
SL103_RS06170	COG0406	alpha-ribazole phosphatase activity
SL103_RS06190	COG1051	belongs to the nudix hydrolase family
SL103_RS06205	COG0495	leucyl-tRNA aminoacylation
SL103_RS06215	COG1307	EDD domain protein, DegV family
SL103_RS06220	COG1555	photosystem II stabilization
SL103_RS06225	COG1234	tRNA 3'-trailer cleavage
SL103_RS06230	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SL103_RS06250	COG0268	Binds directly to 16S ribosomal RNA
SL103_RS06255	COG0481	GTPase activity
SL103_RS06290	COG1420	regulation of RNA biosynthetic process
SL103_RS06295	COG0484	heat shock protein binding
SL103_RS06320	COG0537	adenosine 5'-monophosphoramidase activity
SL103_RS06325	COG1234	tRNA 3'-trailer cleavage
SL103_RS06335	COG4948	Mandelate Racemase Muconate Lactonizing
SL103_RS06350	COG1486	melibiose metabolic process
SL103_RS06355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SL103_RS06365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SL103_RS06380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SL103_RS06390	COG2723	6-phospho-beta-galactosidase activity
SL103_RS06405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SL103_RS06420	COG2124	cytochrome p450
SL103_RS06455	COG1381	Involved in DNA repair and RecF pathway recombination
SL103_RS06460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SL103_RS06470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SL103_RS06475	COG1121	(ABC) transporter
SL103_RS06480	COG0803	Belongs to the bacterial solute-binding protein 9 family
SL103_RS06480	COG3443	Belongs to the bacterial solute-binding protein 9 family
SL103_RS06485	COG0423	glycine-tRNA ligase activity
SL103_RS06505	COG2197	response regulator
SL103_RS06525	COG0667	Aldo Keto reductase
SL103_RS06530	COG0477	Major facilitator Superfamily
SL103_RS06555	COG1595	DNA-templated transcription, initiation
SL103_RS06560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SL103_RS06560	COG0574	Belongs to the PEP-utilizing enzyme family
SL103_RS06570	COG2175	clavaminate synthase activity
SL103_RS06575	COG0395	ABC-type sugar transport system, permease component
SL103_RS06580	COG1175	transmembrane transport
SL103_RS06585	COG2182	Extracellular solute-binding protein
SL103_RS06630	COG0531	amino acid
SL103_RS06635	COG0640	Transcriptional regulator
SL103_RS06650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SL103_RS06650	COG2146	nitrite reductase [NAD(P)H] activity
SL103_RS06660	COG2197	response regulator
SL103_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS06690	COG1473	amidohydrolase
SL103_RS06705	COG2124	cytochrome p450
SL103_RS06710	COG0667	Aldo Keto reductase
SL103_RS06750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SL103_RS06760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SL103_RS06775	COG0358	DNA primase activity
SL103_RS06780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SL103_RS06785	COG1070	Carbohydrate kinase
SL103_RS06825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SL103_RS06830	COG0588	phosphoglycerate mutase activity
SL103_RS06835	COG1077	Cell shape determining protein MreB Mrl
SL103_RS06850	COG0477	Major facilitator Superfamily
SL103_RS06855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SL103_RS06865	COG2130	NADP-dependent
SL103_RS06870	COG1764	response to oxidative stress
SL103_RS06875	COG1609	Transcriptional regulator
SL103_RS06880	COG1129	ABC transporter
SL103_RS06885	COG1172	Belongs to the binding-protein-dependent transport system permease family
SL103_RS06890	COG1879	ABC-type sugar transport system periplasmic component
SL103_RS06895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SL103_RS06900	COG2423	ornithine cyclodeaminase activity
SL103_RS06955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SL103_RS06960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SL103_RS06965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SL103_RS06970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SL103_RS06990	COG0789	Transcriptional regulator
SL103_RS07010	COG2197	response regulator
SL103_RS07015	COG4585	Histidine kinase
SL103_RS07030	COG1309	transcriptional regulator
SL103_RS07035	COG0477	Major facilitator Superfamily
SL103_RS07045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SL103_RS07090	COG1358	cellular component organization or biogenesis
SL103_RS07115	COG0800	Aldolase
SL103_RS07145	COG0582	viral genome integration into host DNA
SL103_RS07230	COG2816	NAD+ diphosphatase activity
SL103_RS07280	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SL103_RS07285	COG0596	Alpha beta hydrolase
SL103_RS07300	COG1072	(Pantothenic acid kinase))
SL103_RS07305	COG0662	Cupin 2, conserved barrel domain protein
SL103_RS07485	COG0477	Major facilitator Superfamily
SL103_RS07495	COG1595	DNA-templated transcription, initiation
SL103_RS07500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SL103_RS07525	COG2124	cytochrome p450
SL103_RS07530	COG0183	Belongs to the thiolase family
SL103_RS07545	COG3845	ABC transporter
SL103_RS07580	COG4221	oxidoreductase activity
SL103_RS07585	COG1309	transcriptional regulator
SL103_RS07590	COG1309	transcriptional regulator
SL103_RS07595	COG0438	transferase activity, transferring glycosyl groups
SL103_RS07615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS07625	COG0860	N-Acetylmuramoyl-L-alanine amidase
SL103_RS07630	COG3510	cephalosporin hydroxylase
SL103_RS07635	COG1960	acyl-CoA dehydrogenase activity
SL103_RS07640	COG0183	Belongs to the thiolase family
SL103_RS07670	COG2197	response regulator
SL103_RS07675	COG4585	Histidine kinase
SL103_RS07685	COG1131	(ABC) transporter
SL103_RS07690	COG2030	dehydratase
SL103_RS07700	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS07720	COG0800	Aldolase
SL103_RS07725	COG3022	response to hydroperoxide
SL103_RS07730	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
SL103_RS07820	COG2814	Major facilitator Superfamily
SL103_RS07825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SL103_RS07850	COG0672	)-iron permease
SL103_RS07855	COG2837	iron assimilation
SL103_RS07870	COG5398	heme oxygenase
SL103_RS07895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SL103_RS07900	COG2186	Transcriptional regulator
SL103_RS07915	COG1175	transmembrane transport
SL103_RS07920	COG0395	ABC-type sugar transport system, permease component
SL103_RS07935	COG1994	Peptidase M50
SL103_RS07955	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SL103_RS07960	COG0477	Major facilitator Superfamily
SL103_RS07965	COG1309	transcriptional regulator
SL103_RS07975	COG2814	Major facilitator Superfamily
SL103_RS07980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SL103_RS07980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SL103_RS07985	COG2132	Multicopper oxidase
SL103_RS07995	COG2267	carboxylic ester hydrolase activity
SL103_RS08015	COG0174	glutamine synthetase
SL103_RS08020	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SL103_RS08030	COG1609	Transcriptional regulator
SL103_RS08035	COG0366	Alpha amylase catalytic
SL103_RS08040	COG2182	Extracellular solute-binding protein
SL103_RS08045	COG1175	transmembrane transport
SL103_RS08050	COG0395	ABC-type sugar transport system, permease component
SL103_RS08055	COG0366	Alpha amylase catalytic
SL103_RS08100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SL103_RS08105	COG0456	acetyltransferase
SL103_RS08175	COG0745	RESPONSE REGULATOR receiver
SL103_RS08195	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS08210	COG1902	pentaerythritol trinitrate reductase activity
SL103_RS08210	COG0446	pyridine nucleotide-disulphide oxidoreductase
SL103_RS08320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SL103_RS08325	COG0321	lipoyl(octanoyl) transferase activity
SL103_RS08355	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS08365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SL103_RS08375	COG0508	dehydrogenase complex catalyzes the overall conversion of
SL103_RS08380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SL103_RS08385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SL103_RS08390	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SL103_RS08405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SL103_RS08405	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SL103_RS08410	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SL103_RS08445	COG4585	Histidine kinase
SL103_RS08450	COG2197	response regulator
SL103_RS08455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SL103_RS08480	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SL103_RS08500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SL103_RS08510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SL103_RS08515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SL103_RS08525	COG1376	ErfK ybiS ycfS ynhG family protein
SL103_RS08535	COG1845	cytochrome c oxidase, subunit III
SL103_RS08540	COG2010	Cytochrome c
SL103_RS08545	COG0723	plastoquinol--plastocyanin reductase activity
SL103_RS08550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SL103_RS08555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SL103_RS08560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SL103_RS08605	COG0438	transferase activity, transferring glycosyl groups
SL103_RS08625	COG0003	Pfam Anion-transporting ATPase
SL103_RS08635	COG1940	carbohydrate kinase activity
SL103_RS08665	COG2197	response regulator
SL103_RS08670	COG0205	6-phosphofructokinase activity
SL103_RS08675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SL103_RS08685	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SL103_RS08695	COG2193	ferroxidase activity
SL103_RS08700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SL103_RS08705	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SL103_RS08710	COG2815	serine threonine protein kinase
SL103_RS08710	COG0515	serine threonine protein kinase
SL103_RS08715	COG2022	thiamine diphosphate biosynthetic process
SL103_RS08725	COG2022	thiamine diphosphate biosynthetic process
SL103_RS08725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SL103_RS08740	COG0352	thiamine-phosphate diphosphorylase activity
SL103_RS08755	COG1233	COG1233 Phytoene dehydrogenase and related
SL103_RS08765	COG1309	transcriptional regulator
SL103_RS08775	COG1129	ABC transporter
SL103_RS08785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SL103_RS08805	COG0714	Associated with various cellular activities
SL103_RS08815	COG0275	rRNA processing
SL103_RS08830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SL103_RS08835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SL103_RS08840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SL103_RS08845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SL103_RS08855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SL103_RS08860	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SL103_RS08865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SL103_RS08870	COG1496	oxidoreductase activity
SL103_RS08880	COG1799	cell septum assembly
SL103_RS08895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SL103_RS08910	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SL103_RS08965	COG0587	DNA-directed DNA polymerase activity
SL103_RS08970	COG1432	Conserved Protein
SL103_RS08990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SL103_RS09005	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SL103_RS09010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SL103_RS09015	COG0131	Imidazoleglycerol-phosphate dehydratase
SL103_RS09020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SL103_RS09025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SL103_RS09030	COG0251	oxidation-reduction process
SL103_RS09035	COG0107	imidazoleglycerol-phosphate synthase activity
SL103_RS09040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SL103_RS09045	COG1053	succinate dehydrogenase
SL103_RS09055	COG0583	DNA-binding transcription factor activity
SL103_RS09065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SL103_RS09070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SL103_RS09090	COG0134	indole-3-glycerol-phosphate synthase activity
SL103_RS09100	COG0133	tryptophan synthase activity
SL103_RS09105	COG0159	tryptophan synthase activity
SL103_RS09115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SL103_RS09125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SL103_RS09155	COG0070	glutamate synthase
SL103_RS09155	COG0069	glutamate synthase activity
SL103_RS09155	COG0067	glutamate synthase
SL103_RS09170	COG0640	Transcriptional regulator
SL103_RS09175	COG3467	pyridoxamine 5'-phosphate
SL103_RS09195	COG0596	Alpha beta hydrolase
SL103_RS09225	COG0366	Alpha amylase catalytic
SL103_RS09225	COG1470	cell adhesion involved in biofilm formation
SL103_RS09255	COG0737	Belongs to the 5'-nucleotidase family
SL103_RS09300	COG0559	Belongs to the binding-protein-dependent transport system permease family
SL103_RS09310	COG2050	protein possibly involved in aromatic compounds catabolism
SL103_RS09345	COG1643	Atp-dependent helicase
SL103_RS09350	COG2226	methyltransferase
SL103_RS09365	COG0237	dephospho-CoA kinase activity
SL103_RS09390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SL103_RS09440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SL103_RS09445	COG0584	glycerophosphoryl diester phosphodiesterase
SL103_RS09450	COG0556	nucleotide-excision repair
SL103_RS09490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SL103_RS09500	COG1609	Transcriptional regulator
SL103_RS09505	COG1063	alcohol dehydrogenase
SL103_RS09510	COG2814	Major facilitator Superfamily
SL103_RS09535	COG0322	excinuclease ABC activity
SL103_RS09540	COG1660	Displays ATPase and GTPase activities
SL103_RS09545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SL103_RS09550	COG1481	regulation of sporulation
SL103_RS09555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SL103_RS09560	COG0126	phosphoglycerate kinase activity
SL103_RS09565	COG0149	triose-phosphate isomerase activity
SL103_RS09570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SL103_RS09580	COG0166	Belongs to the GPI family
SL103_RS09585	COG0363	glucosamine-6-phosphate deaminase activity
SL103_RS09600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SL103_RS09605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SL103_RS09610	COG0109	protoheme IX farnesyltransferase activity
SL103_RS09635	COG1131	(ABC) transporter
SL103_RS09650	COG0719	Fe-S assembly protein
SL103_RS09660	COG0396	ATPase activity
SL103_RS09665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SL103_RS09670	COG0822	iron-sulfur transferase activity
SL103_RS09675	COG2151	metal-sulfur cluster biosynthetic enzyme
SL103_RS09680	COG2076	Multidrug Resistance protein
SL103_RS09685	COG2171	N-acyltransferase activity
SL103_RS09695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SL103_RS09735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SL103_RS09740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SL103_RS09755	COG4585	Histidine kinase
SL103_RS09760	COG1414	Transcriptional regulator
SL103_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS09820	COG1902	pentaerythritol trinitrate reductase activity
SL103_RS09835	COG1917	Cupin 2, conserved barrel domain protein
SL103_RS09840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SL103_RS09865	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
SL103_RS09880	COG1797	cobyrinic acid a,c-diamide synthase activity
SL103_RS09895	COG1492	cobalamin metabolic process
SL103_RS09900	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SL103_RS09915	COG1653	transport
SL103_RS09930	COG0235	Class ii aldolase
SL103_RS09950	COG0488	(ABC) transporter
SL103_RS10000	COG3387	PFAM Glycoside hydrolase 15-related
SL103_RS10015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SL103_RS10020	COG3340	Belongs to the peptidase S51 family
SL103_RS10040	COG1404	Belongs to the peptidase S8 family
SL103_RS10055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SL103_RS10060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SL103_RS10075	COG2261	transglycosylase associated protein
SL103_RS10080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SL103_RS10115	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS10120	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SL103_RS10125	COG2186	Transcriptional regulator
SL103_RS10145	COG3830	Belongs to the UPF0237 family
SL103_RS10145	COG0560	Phosphoserine phosphatase
SL103_RS10150	COG1716	ATPase activity
SL103_RS10150	COG1131	(ABC) transporter
SL103_RS10150	COG0842	Transport permease protein
SL103_RS10175	COG4585	Histidine kinase
SL103_RS10180	COG2197	response regulator
SL103_RS10200	COG1119	ATPase activity
SL103_RS10225	COG1881	PFAM PEBP family protein
SL103_RS10235	COG2094	Belongs to the DNA glycosylase MPG family
SL103_RS10275	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SL103_RS10290	COG0647	UMP catabolic process
SL103_RS10305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SL103_RS10310	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SL103_RS10315	COG1120	ATPase activity
SL103_RS10335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SL103_RS10345	COG0497	DNA recombination
SL103_RS10385	COG3387	PFAM Glycoside hydrolase 15-related
SL103_RS10390	COG0504	CTP synthase activity
SL103_RS10395	COG0494	nUDIX hydrolase
SL103_RS10405	COG0686	Belongs to the AlaDH PNT family
SL103_RS10420	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SL103_RS10425	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SL103_RS10430	COG1187	pseudouridine synthase activity
SL103_RS10435	COG1397	ADP-ribosylglycohydrolase
SL103_RS10455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SL103_RS10465	COG1160	GTP binding
SL103_RS10480	COG3583	domain protein
SL103_RS10485	COG0438	transferase activity, transferring glycosyl groups
SL103_RS10505	COG0671	phosphoesterase, PA-phosphatase related
SL103_RS10515	COG0477	Major facilitator Superfamily
SL103_RS10520	COG1960	acyl-CoA dehydrogenase activity
SL103_RS10525	COG1799	cell septum assembly
SL103_RS10530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SL103_RS10540	COG0765	amino acid transport
SL103_RS10555	COG1126	abc transporter atp-binding protein
SL103_RS10560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SL103_RS10565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS10570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS10585	COG0330	HflC and HflK could
SL103_RS10605	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS10615	COG0587	DNA-directed DNA polymerase activity
SL103_RS10620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SL103_RS10645	COG0531	amino acid
SL103_RS10650	COG1522	sequence-specific DNA binding
SL103_RS10660	COG2226	methyltransferase
SL103_RS10670	COG0367	asparagine synthase
SL103_RS10675	COG1725	Transcriptional regulator
SL103_RS10680	COG1834	amidinotransferase
SL103_RS10715	COG1254	Belongs to the acylphosphatase family
SL103_RS10720	COG0156	8-amino-7-oxononanoate synthase activity
SL103_RS10725	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS10735	COG3664	PFAM glycoside hydrolase family 39
SL103_RS10755	COG0463	Glycosyl transferase, family 2
SL103_RS10790	COG2814	Major facilitator Superfamily
SL103_RS10790	COG0477	Major facilitator Superfamily
SL103_RS10795	COG2188	Transcriptional regulator
SL103_RS10800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SL103_RS10805	COG1309	transcriptional regulator
SL103_RS10810	COG0243	molybdopterin cofactor binding
SL103_RS10815	COG2851	Citrate transporter
SL103_RS10830	COG4106	trans-aconitate 2-methyltransferase activity
SL103_RS10845	COG1960	acyl-CoA dehydrogenase activity
SL103_RS10915	COG1819	glycosyl
SL103_RS10920	COG2226	methyltransferase
SL103_RS10930	COG3876	Protein conserved in bacteria
SL103_RS10940	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS10945	COG1309	transcriptional regulator
SL103_RS10970	COG2149	membrane
SL103_RS10975	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SL103_RS11015	COG2205	protein histidine kinase activity
SL103_RS11020	COG0745	RESPONSE REGULATOR receiver
SL103_RS11030	COG2124	cytochrome p450
SL103_RS11035	COG0488	(ABC) transporter
SL103_RS11065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SL103_RS11065	COG0515	serine threonine protein kinase
SL103_RS11085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SL103_RS11110	COG0667	Aldo Keto reductase
SL103_RS11115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS11125	COG0598	Magnesium transport protein CorA
SL103_RS11145	COG0215	cysteine-tRNA ligase activity
SL103_RS11155	COG4948	Mandelate Racemase Muconate Lactonizing
SL103_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS11170	COG1129	ABC transporter
SL103_RS11190	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS11195	COG2186	Transcriptional regulator
SL103_RS11205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SL103_RS11210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SL103_RS11215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SL103_RS11220	COG1414	Transcriptional regulator
SL103_RS11225	COG1410	methionine synthase
SL103_RS11225	COG0646	methionine synthase
SL103_RS11230	COG0546	phosphoglycolate phosphatase activity
SL103_RS11235	COG4166	transmembrane transport
SL103_RS11245	COG2197	response regulator
SL103_RS11255	COG0517	IMP dehydrogenase activity
SL103_RS11255	COG1994	Peptidase M50
SL103_RS11275	COG1222	aaa ATPase
SL103_RS11280	COG4122	O-methyltransferase activity
SL103_RS11290	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SL103_RS11295	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SL103_RS11300	COG1609	Transcriptional regulator
SL103_RS11310	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SL103_RS11325	COG2378	regulation of single-species biofilm formation
SL103_RS11345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SL103_RS11350	COG0805	protein transport
SL103_RS11360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS11365	COG3254	rhamnose metabolic process
SL103_RS11390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SL103_RS11395	COG0517	IMP dehydrogenase activity
SL103_RS11395	COG4175	Glycine betaine
SL103_RS11430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SL103_RS11435	COG0531	amino acid
SL103_RS11440	COG2186	Transcriptional regulator
SL103_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS11485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SL103_RS11495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SL103_RS11500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SL103_RS11505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SL103_RS11510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SL103_RS11515	COG5002	protein histidine kinase activity
SL103_RS11520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SL103_RS11525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SL103_RS11525	COG0072	phenylalanine-tRNA ligase activity
SL103_RS11540	COG1051	belongs to the nudix hydrolase family
SL103_RS11555	COG1649	PFAM Uncharacterised BCR, COG1649
SL103_RS11565	COG0697	spore germination
SL103_RS11610	COG4106	trans-aconitate 2-methyltransferase activity
SL103_RS11620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SL103_RS11625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SL103_RS11630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SL103_RS11635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SL103_RS11640	COG1438	arginine binding
SL103_RS11655	COG0137	argininosuccinate synthase activity
SL103_RS11660	COG0165	Argininosuccinate lyase
SL103_RS11670	COG0477	Major facilitator Superfamily
SL103_RS11685	COG0584	glycerophosphoryl diester phosphodiesterase
SL103_RS11710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SL103_RS11715	COG2011	ABC-type metal ion transport system permease component
SL103_RS11720	COG1464	Belongs to the NlpA lipoprotein family
SL103_RS11735	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SL103_RS11740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SL103_RS11740	COG1648	precorrin-2 dehydrogenase activity
SL103_RS11795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SL103_RS11850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SL103_RS11865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SL103_RS11900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SL103_RS11905	COG1560	Kdo2-lipid A biosynthetic process
SL103_RS11910	COG0438	transferase activity, transferring glycosyl groups
SL103_RS11920	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SL103_RS11925	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SL103_RS11930	COG0217	transcriptional regulatory protein
SL103_RS11935	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SL103_RS11940	COG0632	four-way junction helicase activity
SL103_RS11945	COG2255	four-way junction helicase activity
SL103_RS11955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SL103_RS11960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SL103_RS11965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SL103_RS11970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SL103_RS11975	COG1196	nuclear chromosome segregation
SL103_RS11980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SL103_RS11990	COG0124	histidyl-tRNA synthetase
SL103_RS12010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SL103_RS12030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SL103_RS12035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SL103_RS12045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SL103_RS12050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SL103_RS12055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SL103_RS12060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SL103_RS12065	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SL103_RS12075	COG0006	proline dipeptidase activity
SL103_RS12080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SL103_RS12085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SL103_RS12095	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SL103_RS12100	COG0540	Belongs to the ATCase OTCase family
SL103_RS12105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SL103_RS12115	COG0505	Belongs to the CarA family
SL103_RS12120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SL103_RS12125	COG0167	dihydroorotate dehydrogenase activity
SL103_RS12130	COG0284	orotidine-5'-phosphate decarboxylase activity
SL103_RS12155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SL103_RS12170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SL103_RS12180	COG1309	transcriptional regulator
SL103_RS12185	COG0300	oxidoreductase activity
SL103_RS12200	COG1309	transcriptional regulator
SL103_RS12210	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS12215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SL103_RS12220	COG2390	Transcriptional regulator
SL103_RS12240	COG0531	amino acid
SL103_RS12250	COG0477	Major facilitator Superfamily
SL103_RS12265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SL103_RS12275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS12285	COG2233	PERMEase
SL103_RS12295	COG2223	nitrite transmembrane transporter activity
SL103_RS12300	COG1846	Transcriptional regulator
SL103_RS12300	COG1940	carbohydrate kinase activity
SL103_RS12305	COG1090	epimerase
SL103_RS12320	COG3201	nicotinamide mononucleotide transporter
SL103_RS12325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SL103_RS12325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SL103_RS12330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SL103_RS12335	COG0140	phosphoribosyl-ATP diphosphatase activity
SL103_RS12340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SL103_RS12395	COG0456	acetyltransferase
SL103_RS12395	COG3153	acetyltransferase
SL103_RS12435	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS12465	COG0671	phosphoesterase, PA-phosphatase related
SL103_RS12495	COG0604	alcohol dehydrogenase
SL103_RS12495	COG3321	synthase
SL103_RS12515	COG2124	cytochrome p450
SL103_RS12560	COG0069	glutamate synthase activity
SL103_RS12565	COG0017	Asparaginyl-tRNA synthetase
SL103_RS12585	COG2124	cytochrome p450
SL103_RS12610	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SL103_RS12630	COG2197	response regulator
SL103_RS12640	COG0456	acetyltransferase
SL103_RS12650	COG0765	amino acid transport
SL103_RS12660	COG0584	glycerophosphoryl diester phosphodiesterase
SL103_RS12710	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SL103_RS12720	COG2318	DinB family
SL103_RS12740	COG0515	serine threonine protein kinase
SL103_RS12745	COG3345	alpha-galactosidase
SL103_RS12760	COG0395	ABC-type sugar transport system, permease component
SL103_RS12765	COG0494	nUDIX hydrolase
SL103_RS12775	COG0445	tRNA wobble uridine modification
SL103_RS12790	COG4585	Histidine kinase
SL103_RS12795	COG2197	response regulator
SL103_RS12805	COG2223	nitrite transmembrane transporter activity
SL103_RS12810	COG1940	carbohydrate kinase activity
SL103_RS12860	COG1349	DNA-binding transcription factor activity
SL103_RS12870	COG0464	growth
SL103_RS12890	COG3217	Mosc domain protein beta barrel domain protein
SL103_RS12890	COG0633	Ferredoxin
SL103_RS12905	COG0463	Glycosyl transferase, family 2
SL103_RS12910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SL103_RS12920	COG2816	NAD+ diphosphatase activity
SL103_RS12930	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS12965	COG1191	sigma factor activity
SL103_RS13015	COG0647	UMP catabolic process
SL103_RS13035	COG1309	transcriptional regulator
SL103_RS13040	COG0590	tRNA wobble adenosine to inosine editing
SL103_RS13045	COG3224	Antibiotic biosynthesis monooxygenase
SL103_RS13055	COG1793	dna ligase
SL103_RS13065	COG1063	alcohol dehydrogenase
SL103_RS13070	COG0395	ABC-type sugar transport system, permease component
SL103_RS13115	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS13140	COG1461	Dihydroxyacetone kinase
SL103_RS13145	COG2376	Dihydroxyacetone kinase
SL103_RS13150	COG2208	phosphoserine phosphatase activity
SL103_RS13150	COG2770	Histidine kinase
SL103_RS13240	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SL103_RS13250	COG1793	dna ligase
SL103_RS13250	COG3285	dna ligase
SL103_RS13265	COG1007	ATP synthesis coupled electron transport
SL103_RS13270	COG1006	Multisubunit Na H antiporter MnhC subunit
SL103_RS13290	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SL103_RS13305	COG0243	molybdopterin cofactor binding
SL103_RS13330	COG1960	acyl-CoA dehydrogenase activity
SL103_RS13340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SL103_RS13340	COG2080	2 iron, 2 sulfur cluster binding
SL103_RS13355	COG0515	serine threonine protein kinase
SL103_RS13370	COG2070	2-Nitropropane dioxygenase
SL103_RS13380	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS13395	COG2267	carboxylic ester hydrolase activity
SL103_RS13410	COG1024	Enoyl-CoA hydratase
SL103_RS13500	COG0438	transferase activity, transferring glycosyl groups
SL103_RS13530	COG3511	phospholipase C
SL103_RS13550	COG1984	allophanate hydrolase subunit 2
SL103_RS13555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SL103_RS13560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SL103_RS13580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SL103_RS13610	COG1414	Transcriptional regulator
SL103_RS13615	COG2146	nitrite reductase [NAD(P)H] activity
SL103_RS13650	COG0596	Alpha beta hydrolase
SL103_RS13665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SL103_RS13670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SL103_RS13680	COG0494	nUDIX hydrolase
SL103_RS13690	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SL103_RS13700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SL103_RS13710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SL103_RS13740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SL103_RS13780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SL103_RS13790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SL103_RS13790	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SL103_RS13825	COG0702	epimerase
SL103_RS13835	COG1819	glycosyl
SL103_RS13895	COG0697	spore germination
SL103_RS13900	COG0583	DNA-binding transcription factor activity
SL103_RS13910	COG0825	malonyl-CoA metabolic process
SL103_RS13910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SL103_RS13915	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS13995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS14000	COG2814	Major facilitator Superfamily
SL103_RS14035	COG2267	carboxylic ester hydrolase activity
SL103_RS14090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SL103_RS14120	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SL103_RS14130	COG1132	(ABC) transporter
SL103_RS14150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SL103_RS14160	COG0386	Belongs to the glutathione peroxidase family
SL103_RS14185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SL103_RS14190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SL103_RS14255	COG0297	glycogen (starch) synthase activity
SL103_RS14265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SL103_RS14265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SL103_RS14275	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SL103_RS14290	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SL103_RS14325	COG2814	Major facilitator Superfamily
SL103_RS14350	COG3585	molybdate ion transport
SL103_RS14375	COG1309	transcriptional regulator
SL103_RS14395	COG0477	Major facilitator Superfamily
SL103_RS14410	COG1024	Enoyl-CoA hydratase
SL103_RS14410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SL103_RS14415	COG0745	RESPONSE REGULATOR receiver
SL103_RS14445	COG2318	DinB family
SL103_RS14480	COG5001	Diguanylate cyclase
SL103_RS14490	COG3387	PFAM Glycoside hydrolase 15-related
SL103_RS14520	COG1063	alcohol dehydrogenase
SL103_RS14525	COG0156	8-amino-7-oxononanoate synthase activity
SL103_RS14530	COG0583	DNA-binding transcription factor activity
SL103_RS14540	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SL103_RS14540	COG1796	DNA polymerase
SL103_RS14555	COG2274	protein secretion by the type I secretion system
SL103_RS14575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SL103_RS14580	COG1120	ATPase activity
SL103_RS14650	COG0019	diaminopimelate decarboxylase activity
SL103_RS14655	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SL103_RS14655	COG2508	Transcriptional regulator
SL103_RS14665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS14670	COG1959	2 iron, 2 sulfur cluster binding
SL103_RS14710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SL103_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS14780	COG2268	Band 7 protein
SL103_RS14800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SL103_RS14805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SL103_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS14840	COG0531	amino acid
SL103_RS14855	COG0640	Transcriptional regulator
SL103_RS14880	COG2186	Transcriptional regulator
SL103_RS14885	COG4565	transcriptional regulatory protein
SL103_RS14890	COG3290	protein histidine kinase activity
SL103_RS14900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SL103_RS14930	COG0596	Alpha beta hydrolase
SL103_RS14935	COG1864	DNA RNA non-specific endonuclease
SL103_RS14935	COG3591	Belongs to the peptidase S1B family
SL103_RS14960	COG0542	response to heat
SL103_RS14965	COG1573	uracil-dna glycosylase
SL103_RS14995	COG1960	acyl-CoA dehydrogenase activity
SL103_RS15000	COG1024	Enoyl-CoA hydratase
SL103_RS15010	COG0183	Belongs to the thiolase family
SL103_RS15030	COG1024	Enoyl-CoA hydratase
SL103_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS15045	COG0789	Transcriptional regulator
SL103_RS15085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SL103_RS15105	COG3938	Belongs to the proline racemase family
SL103_RS15125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SL103_RS15150	COG0701	Predicted permease
SL103_RS15155	COG4214	carbohydrate transport
SL103_RS15165	COG4213	ABC transporter substrate-binding protein
SL103_RS15195	COG1113	amino acid transport
SL103_RS15215	COG1968	undecaprenyl-diphosphatase activity
SL103_RS15305	COG0697	spore germination
SL103_RS15340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SL103_RS15350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SL103_RS15365	COG2890	protein-(glutamine-N5) methyltransferase activity
SL103_RS15385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SL103_RS15400	COG1017	nitric oxide dioxygenase activity
SL103_RS15400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SL103_RS15405	COG0745	RESPONSE REGULATOR receiver
SL103_RS15410	COG2205	protein histidine kinase activity
SL103_RS15415	COG2326	polyphosphate kinase activity
SL103_RS15420	COG0516	GMP reductase activity
SL103_RS15420	COG0517	IMP dehydrogenase activity
SL103_RS15425	COG2239	Acts as a magnesium transporter
SL103_RS15460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SL103_RS15485	COG2837	iron assimilation
SL103_RS15500	COG0738	Major facilitator superfamily
SL103_RS15505	COG5634	Uncharacterized conserved protein (DUF2278)
SL103_RS15545	COG1733	regulation of RNA biosynthetic process
SL103_RS15570	COG0009	L-threonylcarbamoyladenylate synthase
SL103_RS15580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS15680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS15700	COG2017	converts alpha-aldose to the beta-anomer
SL103_RS15710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS15720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS15720	COG3321	synthase
SL103_RS15720	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS15720	COG0300	oxidoreductase activity
SL103_RS15760	COG1129	ABC transporter
SL103_RS15765	COG3284	Transcriptional regulator
SL103_RS15780	COG4948	Mandelate Racemase Muconate Lactonizing
SL103_RS15785	COG2610	gluconate transmembrane transporter activity
SL103_RS15790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SL103_RS15795	COG0668	transmembrane transport
SL103_RS15805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SL103_RS15825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SL103_RS15830	COG0640	Transcriptional regulator
SL103_RS15845	COG2318	DinB family
SL103_RS15850	COG1720	tRNA m6t6A37 methyltransferase activity
SL103_RS15860	COG2197	response regulator
SL103_RS15885	COG1132	(ABC) transporter
SL103_RS15890	COG1132	(ABC) transporter
SL103_RS15900	COG0515	serine threonine protein kinase
SL103_RS15910	COG2890	protein-(glutamine-N5) methyltransferase activity
SL103_RS15935	COG3469	chitinase activity
SL103_RS15950	COG0596	Alpha beta hydrolase
SL103_RS15975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SL103_RS16000	COG0596	Alpha beta hydrolase
SL103_RS16010	COG2204	response regulator
SL103_RS16015	COG4251	negative regulation of phosphorylation
SL103_RS16020	COG0784	Response regulator, receiver
SL103_RS16035	COG0028	Belongs to the TPP enzyme family
SL103_RS16040	COG0069	glutamate synthase activity
SL103_RS16070	COG3629	intracellular signal transduction
SL103_RS16070	COG3903	Transcriptional regulator
SL103_RS16125	COG0693	protein deglycase activity
SL103_RS16130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SL103_RS16135	COG1136	(ABC) transporter
SL103_RS16150	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS16155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SL103_RS16190	COG1473	amidohydrolase
SL103_RS16200	COG1366	Belongs to the anti-sigma-factor antagonist family
SL103_RS16205	COG1366	Belongs to the anti-sigma-factor antagonist family
SL103_RS16210	COG2172	sigma factor antagonist activity
SL103_RS16220	COG2770	Histidine kinase
SL103_RS16220	COG2208	phosphoserine phosphatase activity
SL103_RS16230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SL103_RS16250	COG3896	Chloramphenicol phosphotransferase-like protein
SL103_RS16260	COG4214	carbohydrate transport
SL103_RS16290	COG1414	Transcriptional regulator
SL103_RS16295	COG3386	PFAM SMP-30 Gluconolaconase
SL103_RS16315	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS16335	COG2010	Cytochrome c
SL103_RS16335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SL103_RS16420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
SL103_RS16425	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS16450	COG1595	DNA-templated transcription, initiation
SL103_RS16470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS16495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS16510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS16530	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SL103_RS16540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SL103_RS16545	COG0583	DNA-binding transcription factor activity
SL103_RS16560	COG0590	tRNA wobble adenosine to inosine editing
SL103_RS16570	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS16620	COG0598	Magnesium transport protein CorA
SL103_RS16645	COG1595	DNA-templated transcription, initiation
SL103_RS16655	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SL103_RS16660	COG3851	Histidine kinase
SL103_RS16665	COG2197	response regulator
SL103_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS16690	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SL103_RS16695	COG2814	Major facilitator Superfamily
SL103_RS16700	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SL103_RS16705	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SL103_RS16705	COG2508	Transcriptional regulator
SL103_RS16710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SL103_RS16720	COG4948	Mandelate Racemase Muconate Lactonizing
SL103_RS16725	COG0596	Alpha beta hydrolase
SL103_RS16730	COG2226	methyltransferase
SL103_RS16730	COG1073	alpha beta
SL103_RS16765	COG0583	DNA-binding transcription factor activity
SL103_RS16770	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS16795	COG0730	response to heat
SL103_RS16800	COG1937	Protein conserved in bacteria
SL103_RS16805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SL103_RS16905	COG2353	YceI-like domain
SL103_RS16910	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SL103_RS16935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SL103_RS16940	COG1414	Transcriptional regulator
SL103_RS17050	COG3629	intracellular signal transduction
SL103_RS17050	COG3903	Transcriptional regulator
SL103_RS17060	COG3903	Transcriptional regulator
SL103_RS17060	COG2197	response regulator
SL103_RS17070	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SL103_RS17075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SL103_RS17095	COG0657	acetylesterase activity
SL103_RS17125	COG0577	efflux transmembrane transporter activity
SL103_RS17130	COG1136	(ABC) transporter
SL103_RS17130	COG0577	efflux transmembrane transporter activity
SL103_RS17135	COG4585	Histidine kinase
SL103_RS17140	COG2197	response regulator
SL103_RS17190	COG1819	glycosyl
SL103_RS17205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SL103_RS17235	COG0702	epimerase
SL103_RS17240	COG1733	regulation of RNA biosynthetic process
SL103_RS17260	COG1191	sigma factor activity
SL103_RS17285	COG3594	Acyltransferase
SL103_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS17305	COG1733	regulation of RNA biosynthetic process
SL103_RS17315	COG2124	cytochrome p450
SL103_RS17330	COG1063	alcohol dehydrogenase
SL103_RS17335	COG1733	regulation of RNA biosynthetic process
SL103_RS17340	COG0596	Alpha beta hydrolase
SL103_RS17370	COG0477	Major facilitator Superfamily
SL103_RS17375	COG0596	Alpha beta hydrolase
SL103_RS17380	COG1597	lipid kinase activity
SL103_RS17430	COG0583	DNA-binding transcription factor activity
SL103_RS17450	COG4977	sequence-specific DNA binding
SL103_RS17480	COG2267	carboxylic ester hydrolase activity
SL103_RS17505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SL103_RS17515	COG0028	Belongs to the TPP enzyme family
SL103_RS17545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SL103_RS17615	COG0586	Pfam SNARE associated Golgi protein
SL103_RS17620	COG4585	Histidine kinase
SL103_RS17625	COG2197	response regulator
SL103_RS17655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SL103_RS17660	COG0583	DNA-binding transcription factor activity
SL103_RS17670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SL103_RS17690	COG2205	protein histidine kinase activity
SL103_RS17710	COG4656	Part of a membrane complex involved in electron transport
SL103_RS17720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SL103_RS17765	COG1794	racemase activity, acting on amino acids and derivatives
SL103_RS17780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SL103_RS17800	COG0477	Major facilitator Superfamily
SL103_RS17805	COG0181	hydroxymethylbilane synthase activity
SL103_RS17835	COG2409	Drug exporters of the RND superfamily
SL103_RS17840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SL103_RS17850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SL103_RS17860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SL103_RS17870	COG3387	PFAM Glycoside hydrolase 15-related
SL103_RS17925	COG1271	oxidase subunit
SL103_RS17930	COG1294	oxidase, subunit
SL103_RS17950	COG0583	DNA-binding transcription factor activity
SL103_RS17980	COG2301	Belongs to the HpcH HpaI aldolase family
SL103_RS18005	COG2197	response regulator
SL103_RS18010	COG4585	Histidine kinase
SL103_RS18035	COG3795	YCII-related domain
SL103_RS18040	COG4941	Belongs to the sigma-70 factor family
SL103_RS18050	COG2814	Major facilitator Superfamily
SL103_RS18055	COG1063	alcohol dehydrogenase
SL103_RS18060	COG1349	DNA-binding transcription factor activity
SL103_RS18115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SL103_RS18115	COG1017	nitric oxide dioxygenase activity
SL103_RS18120	COG1959	2 iron, 2 sulfur cluster binding
SL103_RS18130	COG1733	regulation of RNA biosynthetic process
SL103_RS18165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SL103_RS18175	COG2207	Transcriptional regulator
SL103_RS18215	COG0137	argininosuccinate synthase activity
SL103_RS18330	COG0523	cobalamin synthesis protein
SL103_RS18390	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS18400	COG1737	Transcriptional regulator
SL103_RS18415	COG0765	amino acid transport
SL103_RS18430	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS18435	COG0531	amino acid
SL103_RS18445	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS18455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SL103_RS18465	COG1960	acyl-CoA dehydrogenase activity
SL103_RS18480	COG1595	DNA-templated transcription, initiation
SL103_RS18505	COG0577	efflux transmembrane transporter activity
SL103_RS18510	COG1136	(ABC) transporter
SL103_RS18510	COG0577	efflux transmembrane transporter activity
SL103_RS18565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SL103_RS18565	COG0189	ligase activity
SL103_RS18575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SL103_RS18580	COG4948	Mandelate Racemase Muconate Lactonizing
SL103_RS18590	COG2226	methyltransferase
SL103_RS18595	COG0747	negative chemotaxis
SL103_RS18600	COG0601	transmembrane transport
SL103_RS18605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SL103_RS18610	COG4172	Belongs to the ABC transporter superfamily
SL103_RS18620	COG0789	Transcriptional regulator
SL103_RS18640	COG0463	Glycosyl transferase, family 2
SL103_RS18645	COG2815	serine threonine protein kinase
SL103_RS18645	COG0515	serine threonine protein kinase
SL103_RS18720	COG3848	Pyruvate phosphate dikinase
SL103_RS18720	COG0574	Belongs to the PEP-utilizing enzyme family
SL103_RS18780	COG0667	Aldo Keto reductase
SL103_RS18865	COG0515	serine threonine protein kinase
SL103_RS18870	COG1132	(ABC) transporter
SL103_RS18945	COG3293	Transposase
SL103_RS18965	COG0702	epimerase
SL103_RS18985	COG1595	DNA-templated transcription, initiation
SL103_RS18990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS19000	COG0436	Aminotransferase
SL103_RS19005	COG1396	sequence-specific DNA binding
SL103_RS19010	COG4733	cellulase activity
SL103_RS19010	COG5297	Belongs to the glycosyl hydrolase family 6
SL103_RS19035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS19040	COG1595	DNA-templated transcription, initiation
SL103_RS19045	COG3842	ATPase activity
SL103_RS19050	COG1511	domain protein
SL103_RS19070	COG0789	Transcriptional regulator
SL103_RS19075	COG1609	Transcriptional regulator
SL103_RS19080	COG3842	ATPase activity
SL103_RS19085	COG1653	transport
SL103_RS19100	COG0366	Alpha amylase catalytic
SL103_RS19120	COG2134	cdp-diacylglycerol pyrophosphatase
SL103_RS19145	COG0596	Alpha beta hydrolase
SL103_RS19165	COG0488	(ABC) transporter
SL103_RS19180	COG1595	DNA-templated transcription, initiation
SL103_RS19195	COG0753	catalase activity
SL103_RS19215	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SL103_RS19245	COG3973	AAA domain
SL103_RS19280	COG0596	Alpha beta hydrolase
SL103_RS19350	COG1309	transcriptional regulator
SL103_RS19360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SL103_RS19365	COG1316	TRANSCRIPTIONal
SL103_RS19370	COG1215	transferase activity, transferring glycosyl groups
SL103_RS19385	COG0531	amino acid
SL103_RS19410	COG0596	Alpha beta hydrolase
SL103_RS19415	COG3226	Transcriptional regulator
SL103_RS19420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SL103_RS19420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SL103_RS19425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SL103_RS19460	COG2208	phosphoserine phosphatase activity
SL103_RS19460	COG2770	Histidine kinase
SL103_RS19465	COG0142	geranyltranstransferase activity
SL103_RS19490	COG2226	methyltransferase
SL103_RS19500	COG3387	PFAM Glycoside hydrolase 15-related
SL103_RS19510	COG1191	sigma factor activity
SL103_RS19535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SL103_RS19540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SL103_RS19545	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SL103_RS19550	COG0110	maltose O-acetyltransferase activity
SL103_RS19555	COG0438	transferase activity, transferring glycosyl groups
SL103_RS19560	COG0297	glycogen (starch) synthase activity
SL103_RS19670	COG0789	Transcriptional regulator
SL103_RS19675	COG2814	Major facilitator Superfamily
SL103_RS19685	COG1686	Belongs to the peptidase S11 family
SL103_RS19690	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SL103_RS19710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SL103_RS19735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SL103_RS19770	COG2423	ornithine cyclodeaminase activity
SL103_RS19775	COG0431	NADPH-dependent FMN reductase
SL103_RS19780	COG4221	oxidoreductase activity
SL103_RS19800	COG0494	nUDIX hydrolase
SL103_RS19805	COG0277	FAD linked oxidase domain protein
SL103_RS19830	COG2207	Transcriptional regulator
SL103_RS19835	COG2223	nitrite transmembrane transporter activity
SL103_RS19840	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SL103_RS19845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SL103_RS19875	COG2205	protein histidine kinase activity
SL103_RS19895	COG0577	efflux transmembrane transporter activity
SL103_RS19895	COG1136	(ABC) transporter
SL103_RS19905	COG1653	transport
SL103_RS19910	COG0366	Alpha amylase catalytic
SL103_RS19915	COG1653	transport
SL103_RS19920	COG1175	transmembrane transport
SL103_RS19925	COG0395	ABC-type sugar transport system, permease component
SL103_RS19960	COG0583	DNA-binding transcription factor activity
SL103_RS19965	COG2340	Cysteine-rich secretory protein family
SL103_RS19975	COG0604	alcohol dehydrogenase
SL103_RS19980	COG1902	pentaerythritol trinitrate reductase activity
SL103_RS19985	COG1846	Transcriptional regulator
SL103_RS20030	COG0328	RNA-DNA hybrid ribonuclease activity
SL103_RS20045	COG0667	Aldo Keto reductase
SL103_RS20075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SL103_RS20130	COG4221	oxidoreductase activity
SL103_RS20150	COG1652	LysM domain
SL103_RS20160	COG0339	signal peptide processing
SL103_RS20170	COG0583	DNA-binding transcription factor activity
SL103_RS20200	COG2188	Transcriptional regulator
SL103_RS20215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SL103_RS20225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SL103_RS20240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SL103_RS20265	COG2124	cytochrome p450
SL103_RS20300	COG2226	methyltransferase
SL103_RS20310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SL103_RS20315	COG3395	kinase activity
SL103_RS20320	COG1349	DNA-binding transcription factor activity
SL103_RS20330	COG3290	protein histidine kinase activity
SL103_RS20355	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS20375	COG1793	dna ligase
SL103_RS20395	COG0531	amino acid
SL103_RS20400	COG0640	Transcriptional regulator
SL103_RS20405	COG0477	Major facilitator Superfamily
SL103_RS20420	COG2837	iron assimilation
SL103_RS20425	COG0309	Hydrogenase expression formation protein (HypE)
SL103_RS20435	COG0298	carbon dioxide binding
SL103_RS20440	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SL103_RS20450	COG0375	protein maturation
SL103_RS20480	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SL103_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS20535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SL103_RS20550	COG2124	cytochrome p450
SL103_RS20560	COG2084	Dehydrogenase
SL103_RS20565	COG3622	Belongs to the hyi family
SL103_RS20570	COG3960	tartronate-semialdehyde synthase activity
SL103_RS20580	COG1846	Transcriptional regulator
SL103_RS20610	COG1960	acyl-CoA dehydrogenase activity
SL103_RS20620	COG0242	peptide deformylase activity
SL103_RS20630	COG3442	glutamine amidotransferase
SL103_RS20635	COG0205	6-phosphofructokinase activity
SL103_RS20640	COG3336	cytochrome c oxidase
SL103_RS20700	COG0829	nickel cation binding
SL103_RS20705	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SL103_RS20710	COG0830	nickel cation binding
SL103_RS20715	COG0804	urea catabolic process
SL103_RS20720	COG0832	Belongs to the urease beta subunit family
SL103_RS20725	COG0831	urea catabolic process
SL103_RS20730	COG2234	aminopeptidase activity
SL103_RS20730	COG4935	Belongs to the peptidase S8 family
SL103_RS20745	COG1902	pentaerythritol trinitrate reductase activity
SL103_RS20750	COG2813	Specifically methylates the guanine in position
SL103_RS20765	COG0492	ferredoxin-NADP+ reductase activity
SL103_RS20775	COG0515	serine threonine protein kinase
SL103_RS20775	COG2815	serine threonine protein kinase
SL103_RS20780	COG2391	methyltransferase activity
SL103_RS20805	COG0488	(ABC) transporter
SL103_RS20820	COG2201	protein-glutamate methylesterase activity
SL103_RS20825	COG0740	serine-type endopeptidase activity
SL103_RS20855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SL103_RS20860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SL103_RS20865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SL103_RS20910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SL103_RS20920	COG3511	phospholipase C
SL103_RS20945	COG1940	carbohydrate kinase activity
SL103_RS20950	COG2188	Transcriptional regulator
SL103_RS20955	COG1595	DNA-templated transcription, initiation
SL103_RS20960	COG0346	lactoylglutathione lyase activity
SL103_RS20990	COG1522	sequence-specific DNA binding
SL103_RS20995	COG0419	ATPase involved in DNA repair
SL103_RS21000	COG0420	3'-5' exonuclease activity
SL103_RS21090	COG1739	Uncharacterized protein family UPF0029
SL103_RS21100	COG1832	CoA-binding protein
SL103_RS21180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SL103_RS21190	COG1968	undecaprenyl-diphosphatase activity
SL103_RS21215	COG2770	Histidine kinase
SL103_RS21215	COG2208	phosphoserine phosphatase activity
SL103_RS21245	COG1940	carbohydrate kinase activity
SL103_RS21255	COG1175	transmembrane transport
SL103_RS21260	COG0395	ABC-type sugar transport system, permease component
SL103_RS21265	COG2723	6-phospho-beta-galactosidase activity
SL103_RS21270	COG1764	response to oxidative stress
SL103_RS21275	COG1846	Transcriptional regulator
SL103_RS21285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SL103_RS21325	COG0739	heme binding
SL103_RS21335	COG1132	(ABC) transporter
SL103_RS21340	COG0702	epimerase
SL103_RS21345	COG1609	Transcriptional regulator
SL103_RS21350	COG1653	transport
SL103_RS21355	COG1175	transmembrane transport
SL103_RS21360	COG0395	ABC-type sugar transport system, permease component
SL103_RS21400	COG1278	Cold shock
SL103_RS21405	COG1686	Belongs to the peptidase S11 family
SL103_RS21410	COG2356	endonuclease I
SL103_RS21435	COG1793	dna ligase
SL103_RS21435	COG3285	dna ligase
SL103_RS21440	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SL103_RS21450	COG3012	SEC-C Motif Domain Protein
SL103_RS21470	COG2364	Membrane
SL103_RS21480	COG2270	Major facilitator Superfamily
SL103_RS21495	COG1216	Glycosyl transferase, family 2
SL103_RS21505	COG1228	amidohydrolase
SL103_RS21510	COG1522	sequence-specific DNA binding
SL103_RS21530	COG1960	acyl-CoA dehydrogenase activity
SL103_RS21545	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS21575	COG0640	Transcriptional regulator
SL103_RS21585	COG1335	isochorismatase
SL103_RS21605	COG3903	Transcriptional regulator
SL103_RS21605	COG3629	intracellular signal transduction
SL103_RS21610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS21615	COG3251	PFAM MbtH domain protein
SL103_RS21620	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SL103_RS21625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS21680	COG2304	oxidoreductase activity
SL103_RS21740	COG1191	sigma factor activity
SL103_RS21755	COG0662	Cupin 2, conserved barrel domain protein
SL103_RS21765	COG2135	peptidase activity
SL103_RS21770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SL103_RS21775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SL103_RS21785	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SL103_RS21810	COG1231	oxidoreductase activity
SL103_RS21815	COG3961	Belongs to the TPP enzyme family
SL103_RS21845	COG1609	Transcriptional regulator
SL103_RS21850	COG1957	nucleoside hydrolase
SL103_RS21855	COG0477	Major facilitator Superfamily
SL103_RS21875	COG1335	isochorismatase
SL103_RS21890	COG0243	molybdopterin cofactor binding
SL103_RS21890	COG3383	formate dehydrogenase (NAD+) activity
SL103_RS21895	COG0437	4 iron, 4 sulfur cluster binding
SL103_RS21905	COG1252	NADH dehydrogenase
SL103_RS21920	COG1302	Protein conserved in bacteria
SL103_RS21930	COG3903	Transcriptional regulator
SL103_RS21930	COG3629	intracellular signal transduction
SL103_RS21955	COG0142	geranyltranstransferase activity
SL103_RS21975	COG1309	transcriptional regulator
SL103_RS22005	COG1902	pentaerythritol trinitrate reductase activity
SL103_RS22015	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SL103_RS22040	COG2706	6-phosphogluconolactonase activity
SL103_RS22085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SL103_RS22090	COG4213	ABC transporter substrate-binding protein
SL103_RS22105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SL103_RS22155	COG2197	response regulator
SL103_RS22185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SL103_RS22190	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SL103_RS22195	COG2080	2 iron, 2 sulfur cluster binding
SL103_RS22205	COG4221	oxidoreductase activity
SL103_RS22210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SL103_RS22220	COG0156	8-amino-7-oxononanoate synthase activity
SL103_RS22230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SL103_RS22235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SL103_RS22240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SL103_RS22255	COG1122	ATPase activity
SL103_RS22260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SL103_RS22265	COG1268	BioY protein
SL103_RS22270	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS22275	COG0183	Belongs to the thiolase family
SL103_RS22380	COG0405	Gamma-glutamyltransferase
SL103_RS22390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SL103_RS22395	COG0583	DNA-binding transcription factor activity
SL103_RS22400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SL103_RS22415	COG2267	carboxylic ester hydrolase activity
SL103_RS22460	COG3291	Pkd domain containing protein
SL103_RS22475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SL103_RS22515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS22550	COG1132	(ABC) transporter
SL103_RS22555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SL103_RS22620	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SL103_RS22630	COG0302	gtp cyclohydrolase
SL103_RS22635	COG0720	synthase
SL103_RS22640	COG0602	queuosine metabolic process
SL103_RS22650	COG3629	intracellular signal transduction
SL103_RS22650	COG3903	Transcriptional regulator
SL103_RS22655	COG4977	sequence-specific DNA binding
SL103_RS22675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SL103_RS22680	COG1116	anion transmembrane transporter activity
SL103_RS22695	COG2072	flavoprotein involved in K transport
SL103_RS22700	COG0477	Major facilitator Superfamily
SL103_RS22705	COG0247	lactate metabolic process
SL103_RS22710	COG1139	Iron-sulfur cluster binding protein
SL103_RS22715	COG1556	Lactate utilization protein
SL103_RS22730	COG1051	belongs to the nudix hydrolase family
SL103_RS22750	COG1132	(ABC) transporter
SL103_RS22785	COG1132	(ABC) transporter
SL103_RS22800	COG1946	Acyl-CoA thioesterase
SL103_RS22810	COG2018	Roadblock/LC7 domain
SL103_RS22850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SL103_RS22875	COG0431	NADPH-dependent FMN reductase
SL103_RS22885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS22895	COG2040	homocysteine
SL103_RS22900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SL103_RS22905	COG0765	amino acid transport
SL103_RS22920	COG3458	cephalosporin-C deacetylase activity
SL103_RS22925	COG2115	Belongs to the xylose isomerase family
SL103_RS22930	COG1070	Carbohydrate kinase
SL103_RS22940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SL103_RS22945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SL103_RS22945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SL103_RS22950	COG3023	N-Acetylmuramoyl-L-alanine amidase
SL103_RS22970	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SL103_RS22970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SL103_RS22980	COG1366	Belongs to the anti-sigma-factor antagonist family
SL103_RS23020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SL103_RS23025	COG0588	phosphoglycerate mutase activity
SL103_RS23030	COG1070	Carbohydrate kinase
SL103_RS23035	COG1070	Carbohydrate kinase
SL103_RS23040	COG2814	Major facilitator Superfamily
SL103_RS23045	COG1349	DNA-binding transcription factor activity
SL103_RS23080	COG1960	acyl-CoA dehydrogenase activity
SL103_RS23085	COG1960	acyl-CoA dehydrogenase activity
SL103_RS23100	COG1388	LysM domain
SL103_RS23100	COG3858	chitin binding
SL103_RS23130	COG3572	ergothioneine biosynthetic process
SL103_RS23135	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SL103_RS23145	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SL103_RS23150	COG0823	Involved in the tonB-independent uptake of proteins
SL103_RS23200	COG3360	Dodecin
SL103_RS23205	COG0531	amino acid
SL103_RS23220	COG3537	Alpha-1,2-mannosidase
SL103_RS23280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SL103_RS23295	COG5183	chlorophyll binding
SL103_RS23295	COG2133	pyrroloquinoline quinone binding
SL103_RS23310	COG2706	6-phosphogluconolactonase activity
SL103_RS23315	COG1113	amino acid transport
SL103_RS23325	COG1960	acyl-CoA dehydrogenase activity
SL103_RS23330	COG1024	Enoyl-CoA hydratase
SL103_RS23340	COG2226	methyltransferase
SL103_RS23365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SL103_RS23375	COG0747	negative chemotaxis
SL103_RS23380	COG1940	carbohydrate kinase activity
SL103_RS23410	COG0174	glutamine synthetase
SL103_RS23425	COG3246	L-lysine catabolic process to acetate
SL103_RS23430	COG1250	3-hydroxyacyl-CoA dehydrogenase
SL103_RS23450	COG1686	Belongs to the peptidase S11 family
SL103_RS23455	COG2124	cytochrome p450
SL103_RS23485	COG3959	Transketolase, thiamine diphosphate binding domain
SL103_RS23490	COG3958	Transketolase
SL103_RS23495	COG2267	carboxylic ester hydrolase activity
SL103_RS23500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SL103_RS23505	COG1960	acyl-CoA dehydrogenase activity
SL103_RS23525	COG2018	Roadblock/LC7 domain
SL103_RS23535	COG0739	heme binding
SL103_RS23555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SL103_RS23580	COG2755	lipolytic protein G-D-S-L family
SL103_RS23585	COG2365	Tyrosine phosphatase family
SL103_RS23595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SL103_RS23610	COG1657	PFAM Prenyltransferase squalene oxidase
SL103_RS23620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SL103_RS23630	COG1562	ergosterol biosynthetic process
SL103_RS23635	COG1134	teichoic acid transport
SL103_RS23670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SL103_RS23700	COG4977	sequence-specific DNA binding
SL103_RS23710	COG2183	response to ionizing radiation
SL103_RS23745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SL103_RS23755	COG2936	dipeptidyl-peptidase activity
SL103_RS23770	COG3568	Endonuclease Exonuclease Phosphatase
SL103_RS23775	COG1113	amino acid transport
SL103_RS23780	COG0789	Transcriptional regulator
SL103_RS23785	COG1024	Enoyl-CoA hydratase
SL103_RS23785	COG1250	3-hydroxyacyl-CoA dehydrogenase
SL103_RS23790	COG0183	Belongs to the thiolase family
SL103_RS23795	COG1960	acyl-CoA dehydrogenase activity
SL103_RS23800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SL103_RS23805	COG1285	pathogenesis
SL103_RS23815	COG3268	Saccharopine dehydrogenase
SL103_RS23820	COG1515	deoxyribonuclease V activity
SL103_RS23825	COG0154	amidase activity
SL103_RS23835	COG2814	Major facilitator Superfamily
SL103_RS23840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SL103_RS23850	COG1349	DNA-binding transcription factor activity
SL103_RS23860	COG1309	transcriptional regulator
SL103_RS23870	COG1846	Transcriptional regulator
SL103_RS23890	COG3226	Transcriptional regulator
SL103_RS23915	COG0745	RESPONSE REGULATOR receiver
SL103_RS23920	COG2205	protein histidine kinase activity
SL103_RS23990	COG1136	(ABC) transporter
SL103_RS24005	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS24010	COG0531	amino acid
SL103_RS24025	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS24030	COG0287	Prephenate dehydrogenase
SL103_RS24030	COG1605	Chorismate mutase
SL103_RS24040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SL103_RS24045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SL103_RS24055	COG3321	synthase
SL103_RS24055	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS24055	COG0604	alcohol dehydrogenase
SL103_RS24070	COG0583	DNA-binding transcription factor activity
SL103_RS24085	COG0656	L-ascorbic acid biosynthetic process
SL103_RS24105	COG1295	ribonuclease BN
SL103_RS24110	COG2154	pterin-4-alpha-carbinolamine dehydratase
SL103_RS24125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SL103_RS24135	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SL103_RS24150	COG0531	amino acid
SL103_RS24160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SL103_RS24185	COG0671	phosphoesterase, PA-phosphatase related
SL103_RS24190	COG2226	methyltransferase
SL103_RS24220	COG0010	Belongs to the arginase family
SL103_RS24230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SL103_RS24245	COG2124	cytochrome p450
SL103_RS24260	COG1619	proteins homologs of microcin C7 resistance protein MccF
SL103_RS24270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SL103_RS24275	COG2362	D-Aminopeptidase
SL103_RS24330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SL103_RS24340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SL103_RS24350	COG1250	3-hydroxyacyl-CoA dehydrogenase
SL103_RS24360	COG0604	alcohol dehydrogenase
SL103_RS24365	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SL103_RS24365	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SL103_RS24370	COG2301	Belongs to the HpcH HpaI aldolase family
SL103_RS24380	COG1960	acyl-CoA dehydrogenase activity
SL103_RS24385	COG0688	phosphatidylethanolamine metabolic process
SL103_RS24395	COG1929	Belongs to the glycerate kinase type-1 family
SL103_RS24420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SL103_RS24430	COG2226	methyltransferase
SL103_RS24435	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SL103_RS24445	COG0483	inositol monophosphate 1-phosphatase activity
SL103_RS24455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SL103_RS24465	COG1953	Uracil, thiamine, allantoin
SL103_RS24470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SL103_RS24475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SL103_RS24485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SL103_RS24500	COG0477	Major facilitator Superfamily
SL103_RS24505	COG1335	isochorismatase
SL103_RS24525	COG0387	Pfam Sodium calcium exchanger
SL103_RS24540	COG2409	Drug exporters of the RND superfamily
SL103_RS24555	COG0435	Glutathione S-transferase
SL103_RS24565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SL103_RS24570	COG2267	carboxylic ester hydrolase activity
SL103_RS24575	COG2226	methyltransferase
SL103_RS24595	COG0765	amino acid transport
SL103_RS24600	COG0765	amino acid transport
SL103_RS24605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SL103_RS24610	COG1126	abc transporter atp-binding protein
SL103_RS24635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS24640	COG3693	PFAM glycoside hydrolase, family 10
SL103_RS24655	COG0431	NADPH-dependent FMN reductase
SL103_RS24665	COG0783	Belongs to the Dps family
SL103_RS24670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SL103_RS24690	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SL103_RS24695	COG1335	isochorismatase
SL103_RS24700	COG2259	Doxx family
SL103_RS24705	COG3619	membrane
SL103_RS24715	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SL103_RS24720	COG1132	(ABC) transporter
SL103_RS24725	COG1294	oxidase, subunit
SL103_RS24730	COG1271	oxidase subunit
SL103_RS24740	COG0395	ABC-type sugar transport system, permease component
SL103_RS24745	COG1175	transmembrane transport
SL103_RS24750	COG2182	Extracellular solute-binding protein
SL103_RS24770	COG2814	Major facilitator Superfamily
SL103_RS24785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS24795	COG2267	carboxylic ester hydrolase activity
SL103_RS24800	COG0531	amino acid
SL103_RS24815	COG1289	transmembrane transporter activity
SL103_RS24825	COG3835	regulator
SL103_RS24835	COG0443	Heat shock 70 kDa protein
SL103_RS24855	COG0542	response to heat
SL103_RS24885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SL103_RS24890	COG4569	acetaldehyde dehydrogenase (acetylating) activity
SL103_RS24895	COG3971	2-oxopent-4-enoate hydratase activity
SL103_RS24900	COG1414	Transcriptional regulator
SL103_RS24940	COG1132	(ABC) transporter
SL103_RS24960	COG0494	nUDIX hydrolase
SL103_RS24980	COG0069	glutamate synthase activity
SL103_RS25020	COG1940	carbohydrate kinase activity
SL103_RS25030	COG1172	Belongs to the binding-protein-dependent transport system permease family
SL103_RS25045	COG2188	Transcriptional regulator
SL103_RS25055	COG2249	NAD(P)H dehydrogenase (quinone) activity
SL103_RS25065	COG0800	Aldolase
SL103_RS25105	COG4266	Belongs to the allantoicase family
SL103_RS25110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SL103_RS25115	COG1953	Uracil, thiamine, allantoin
SL103_RS25125	COG1414	Transcriptional regulator
SL103_RS25150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SL103_RS25170	COG2233	PERMEase
SL103_RS25180	COG2233	PERMEase
SL103_RS25190	COG2351	hydroxyisourate hydrolase activity
SL103_RS25210	COG3622	Belongs to the hyi family
SL103_RS25215	COG2084	Dehydrogenase
SL103_RS25220	COG0028	Belongs to the TPP enzyme family
SL103_RS25225	COG0753	catalase activity
SL103_RS25265	COG2315	Protein conserved in bacteria
SL103_RS25280	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS25325	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS25335	COG0583	DNA-binding transcription factor activity
SL103_RS25350	COG2252	PERMEase
SL103_RS25355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SL103_RS25385	COG1802	Transcriptional regulator
SL103_RS25410	COG0028	Belongs to the TPP enzyme family
SL103_RS25430	COG1162	GTPase activity
SL103_RS25450	COG0346	lactoylglutathione lyase activity
SL103_RS25455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SL103_RS25465	COG3290	protein histidine kinase activity
SL103_RS25530	COG1215	transferase activity, transferring glycosyl groups
SL103_RS25545	COG1716	ATPase activity
SL103_RS25545	COG0842	Transport permease protein
SL103_RS25545	COG1131	(ABC) transporter
SL103_RS25570	COG1376	ErfK ybiS ycfS ynhG family protein
SL103_RS25585	COG0667	Aldo Keto reductase
SL103_RS25590	COG3511	phospholipase C
SL103_RS25600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SL103_RS25605	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SL103_RS25610	COG2080	2 iron, 2 sulfur cluster binding
SL103_RS25625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SL103_RS25670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS25680	COG3485	protocatechuate 3,4-dioxygenase
SL103_RS25685	COG3485	protocatechuate 3,4-dioxygenase
SL103_RS25695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SL103_RS25700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SL103_RS25705	COG1414	Transcriptional regulator
SL103_RS25710	COG2814	Major facilitator Superfamily
SL103_RS25720	COG1960	acyl-CoA dehydrogenase activity
SL103_RS25745	COG2208	phosphoserine phosphatase activity
SL103_RS25745	COG2770	Histidine kinase
SL103_RS25750	COG0596	Alpha beta hydrolase
SL103_RS25775	COG0175	sulfate reduction
SL103_RS25780	COG0529	Catalyzes the synthesis of activated sulfate
SL103_RS25800	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SL103_RS25805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SL103_RS25815	COG0366	Alpha amylase catalytic
SL103_RS25820	COG1609	Transcriptional regulator
SL103_RS25840	COG0477	Major facilitator Superfamily
SL103_RS25880	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS25930	COG0693	protein deglycase activity
SL103_RS25945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SL103_RS25955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SL103_RS26000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SL103_RS26010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SL103_RS26015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SL103_RS26020	COG2197	response regulator
SL103_RS26025	COG4585	Histidine kinase
SL103_RS26080	COG1136	(ABC) transporter
SL103_RS26090	COG1280	lysine exporter protein (LysE YggA)
SL103_RS26115	COG3253	May function as heme-dependent peroxidase
SL103_RS26120	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SL103_RS26125	COG0183	Belongs to the thiolase family
SL103_RS26135	COG0446	pyridine nucleotide-disulphide oxidoreductase
SL103_RS26145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SL103_RS26160	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SL103_RS26170	COG0183	Belongs to the thiolase family
SL103_RS26175	COG1024	Enoyl-CoA hydratase
SL103_RS26175	COG1250	3-hydroxyacyl-CoA dehydrogenase
SL103_RS26185	COG0531	amino acid
SL103_RS26190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SL103_RS26195	COG4214	carbohydrate transport
SL103_RS26205	COG4213	ABC transporter substrate-binding protein
SL103_RS26215	COG0395	ABC-type sugar transport system, permease component
SL103_RS26220	COG1175	transmembrane transport
SL103_RS26225	COG1653	transport
SL103_RS26240	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SL103_RS26245	COG1595	DNA-templated transcription, initiation
SL103_RS26250	COG3480	Lon protease (S16) C-terminal proteolytic domain
SL103_RS26270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SL103_RS26295	COG0484	heat shock protein binding
SL103_RS26360	COG1024	Enoyl-CoA hydratase
SL103_RS26370	COG0531	amino acid
SL103_RS26375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SL103_RS26385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SL103_RS26420	COG1799	cell septum assembly
SL103_RS26425	COG0598	Magnesium transport protein CorA
SL103_RS26430	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SL103_RS26445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SL103_RS26460	COG1796	DNA polymerase
SL103_RS26460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SL103_RS26470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SL103_RS26480	COG0842	Transport permease protein
SL103_RS26520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SL103_RS26525	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SL103_RS26530	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SL103_RS26535	COG0235	Class ii aldolase
SL103_RS26535	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SL103_RS26540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS26545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS26550	COG3251	PFAM MbtH domain protein
SL103_RS26585	COG2175	clavaminate synthase activity
SL103_RS26590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SL103_RS26595	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SL103_RS26615	COG3424	synthase
SL103_RS26620	COG0443	Heat shock 70 kDa protein
SL103_RS26625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SL103_RS26645	COG4044	May play a role in the intracellular transport of hydrophobic ligands
SL103_RS26650	COG0789	Transcriptional regulator
SL103_RS26655	COG0667	Aldo Keto reductase
SL103_RS26660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SL103_RS26675	COG0789	Transcriptional regulator
SL103_RS26695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SL103_RS26700	COG0531	amino acid
SL103_RS26710	COG0569	domain protein
SL103_RS26745	COG0667	Aldo Keto reductase
SL103_RS26750	COG1136	(ABC) transporter
SL103_RS26750	COG0577	efflux transmembrane transporter activity
SL103_RS26760	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SL103_RS26765	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SL103_RS26770	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SL103_RS26785	COG0756	dUTP diphosphatase activity
SL103_RS26810	COG2205	protein histidine kinase activity
SL103_RS26815	COG0745	RESPONSE REGULATOR receiver
SL103_RS26820	COG0483	inositol monophosphate 1-phosphatase activity
SL103_RS26825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SL103_RS26885	COG1435	thymidine kinase activity
SL103_RS26905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SL103_RS26910	COG1802	Transcriptional regulator
SL103_RS26925	COG0612	Peptidase, M16
SL103_RS26930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SL103_RS26940	COG0372	Belongs to the citrate synthase family
SL103_RS26960	COG3290	protein histidine kinase activity
SL103_RS26965	COG4565	transcriptional regulatory protein
SL103_RS26970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SL103_RS26980	COG2197	response regulator
SL103_RS26985	COG4585	Histidine kinase
SL103_RS26995	COG0187	DNA topoisomerase II activity
SL103_RS27010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SL103_RS27015	COG2186	Transcriptional regulator
SL103_RS27050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SL103_RS27065	COG0488	(ABC) transporter
SL103_RS27080	COG0154	amidase activity
SL103_RS27085	COG3226	Transcriptional regulator
SL103_RS27110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SL103_RS27115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SL103_RS27120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SL103_RS27155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SL103_RS27165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SL103_RS27170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SL103_RS27180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SL103_RS27195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SL103_RS27210	COG1278	Cold shock
SL103_RS27215	COG2205	protein histidine kinase activity
SL103_RS27225	COG1126	abc transporter atp-binding protein
SL103_RS27230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SL103_RS27235	COG0765	amino acid transport
SL103_RS27240	COG0765	amino acid transport
SL103_RS27245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SL103_RS27270	COG0628	permease
SL103_RS27300	COG1201	RNA secondary structure unwinding
SL103_RS27305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SL103_RS27315	COG0783	Belongs to the Dps family
SL103_RS27320	COG1396	sequence-specific DNA binding
SL103_RS27325	COG1546	Belongs to the CinA family
SL103_RS27325	COG1058	Belongs to the CinA family
SL103_RS27335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SL103_RS27345	COG1674	ftsk spoiiie
SL103_RS27355	COG3437	response regulator, receiver
SL103_RS27355	COG3850	Histidine kinase
SL103_RS27355	COG2205	protein histidine kinase activity
SL103_RS27355	COG4999	Histidine kinase
SL103_RS27360	COG2208	phosphoserine phosphatase activity
SL103_RS27360	COG2770	Histidine kinase
SL103_RS27390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SL103_RS27395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SL103_RS27400	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SL103_RS27420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SL103_RS27425	COG0612	Peptidase, M16
SL103_RS27430	COG1185	polyribonucleotide nucleotidyltransferase activity
SL103_RS27435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SL103_RS27445	COG1674	ftsk spoiiie
SL103_RS27535	COG0455	bacterial-type flagellum organization
SL103_RS27550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SL103_RS27555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SL103_RS27565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SL103_RS27575	COG0779	Required for maturation of 30S ribosomal subunits
SL103_RS27590	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SL103_RS27595	COG0442	prolyl-tRNA aminoacylation
SL103_RS27615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SL103_RS27620	COG0750	zinc metalloprotease
SL103_RS27625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SL103_RS27635	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS27660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SL103_RS27665	COG1177	transmembrane transport
SL103_RS27670	COG1176	ABC-type spermidine putrescine transport system, permease component I
SL103_RS27675	COG3842	ATPase activity
SL103_RS27685	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS27695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SL103_RS27705	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS27715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SL103_RS27720	COG4181	ATPase activity
SL103_RS27755	COG3842	ATPase activity
SL103_RS27760	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SL103_RS27770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SL103_RS27775	COG0575	Belongs to the CDS family
SL103_RS27780	COG0233	cytoplasmic translational termination
SL103_RS27785	COG0528	UMP kinase activity
SL103_RS27790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SL103_RS27795	COG0052	Belongs to the universal ribosomal protein uS2 family
SL103_RS27805	COG1191	sigma factor activity
SL103_RS27820	COG0792	nuclease activity
SL103_RS27840	COG0681	Belongs to the peptidase S26 family
SL103_RS27850	COG0681	Belongs to the peptidase S26 family
SL103_RS27855	COG0335	large ribosomal subunit rRNA binding
SL103_RS27860	COG0336	Belongs to the RNA methyltransferase TrmD family
SL103_RS27865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SL103_RS27870	COG1837	Belongs to the UPF0109 family
SL103_RS27875	COG0228	four-way junction DNA binding
SL103_RS27895	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SL103_RS27940	COG0477	Major facilitator Superfamily
SL103_RS27945	COG1196	nuclear chromosome segregation
SL103_RS27955	COG1254	Belongs to the acylphosphatase family
SL103_RS27960	COG2340	Cysteine-rich secretory protein family
SL103_RS27970	COG1733	regulation of RNA biosynthetic process
SL103_RS27975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SL103_RS27980	COG0571	ribonuclease III activity
SL103_RS27985	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SL103_RS28000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SL103_RS28005	COG0742	ribosomal rna small subunit methyltransferase
SL103_RS28015	COG1461	Dihydroxyacetone kinase
SL103_RS28020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SL103_RS28025	COG0351	phosphomethylpyrimidine kinase
SL103_RS28045	COG1181	Belongs to the D-alanine--D-alanine ligase family
SL103_RS28050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SL103_RS28060	COG1920	GTP binding
SL103_RS28070	COG0776	regulation of translation
SL103_RS28080	COG0066	3-isopropylmalate dehydratase activity
SL103_RS28085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SL103_RS28090	COG1414	Transcriptional regulator
SL103_RS28125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SL103_RS28130	COG0179	Fumarylacetoacetate (FAA) hydrolase
SL103_RS28145	COG2018	Roadblock/LC7 domain
SL103_RS28165	COG2018	Roadblock/LC7 domain
SL103_RS28190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SL103_RS28195	COG5492	domain, Protein
SL103_RS28205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SL103_RS28215	COG0477	Major facilitator Superfamily
SL103_RS28220	COG1309	transcriptional regulator
SL103_RS28225	COG2957	Belongs to the agmatine deiminase family
SL103_RS28230	COG0804	urea catabolic process
SL103_RS28235	COG0831	urea catabolic process
SL103_RS28235	COG0832	Belongs to the urease beta subunit family
SL103_RS28245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SL103_RS28250	COG0473	3-isopropylmalate dehydrogenase activity
SL103_RS28265	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS28270	COG0506	proline dehydrogenase activity
SL103_RS28295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SL103_RS28300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SL103_RS28305	COG0440	acetolactate synthase activity
SL103_RS28315	COG3300	MHYT domain
SL103_RS28315	COG5001	Diguanylate cyclase
SL103_RS28325	COG0667	Aldo Keto reductase
SL103_RS28330	COG2133	pyrroloquinoline quinone binding
SL103_RS28335	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SL103_RS28335	COG1672	PFAM Archaeal ATPase
SL103_RS28355	COG2409	Drug exporters of the RND superfamily
SL103_RS28380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SL103_RS28390	COG0154	amidase activity
SL103_RS28395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SL103_RS28405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SL103_RS28420	COG1846	Transcriptional regulator
SL103_RS28425	COG4221	oxidoreductase activity
SL103_RS28435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SL103_RS28480	COG0482	sulfurtransferase activity
SL103_RS28505	COG2860	membrane
SL103_RS28510	COG0308	aminopeptidase N
SL103_RS28515	COG4608	Belongs to the ABC transporter superfamily
SL103_RS28520	COG0444	Belongs to the ABC transporter superfamily
SL103_RS28525	COG0601	transmembrane transport
SL103_RS28530	COG0747	negative chemotaxis
SL103_RS28550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SL103_RS28555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SL103_RS28560	COG0509	glycine decarboxylation via glycine cleavage system
SL103_RS28565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SL103_RS28570	COG0531	amino acid
SL103_RS28575	COG1760	l-serine dehydratase
SL103_RS28585	COG0671	phosphoesterase, PA-phosphatase related
SL103_RS28595	COG0586	Pfam SNARE associated Golgi protein
SL103_RS28615	COG0745	RESPONSE REGULATOR receiver
SL103_RS28620	COG0438	transferase activity, transferring glycosyl groups
SL103_RS28630	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SL103_RS28640	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SL103_RS28645	COG0785	Cytochrome C biogenesis protein
SL103_RS28650	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SL103_RS28650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SL103_RS28670	COG1376	ErfK ybiS ycfS ynhG family protein
SL103_RS28675	COG1376	ErfK ybiS ycfS ynhG family protein
SL103_RS28685	COG1132	(ABC) transporter
SL103_RS28690	COG1132	(ABC) transporter
SL103_RS28710	COG1132	(ABC) transporter
SL103_RS28715	COG1132	(ABC) transporter
SL103_RS28735	COG4585	Histidine kinase
SL103_RS28740	COG0366	Alpha amylase catalytic
SL103_RS28755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SL103_RS28760	COG1301	dicarboxylic acid transport
SL103_RS28770	COG4565	transcriptional regulatory protein
SL103_RS28780	COG1175	transmembrane transport
SL103_RS28785	COG0395	ABC-type sugar transport system, permease component
SL103_RS28795	COG1136	(ABC) transporter
SL103_RS28795	COG0577	efflux transmembrane transporter activity
SL103_RS28800	COG0577	efflux transmembrane transporter activity
SL103_RS28805	COG0205	6-phosphofructokinase activity
SL103_RS28810	COG0857	belongs to the CobB CobQ family
SL103_RS28810	COG0280	phosphate acetyltransferase
SL103_RS28815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SL103_RS28850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SL103_RS28855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SL103_RS28860	COG0745	RESPONSE REGULATOR receiver
SL103_RS28865	COG2205	protein histidine kinase activity
SL103_RS28870	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SL103_RS28870	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SL103_RS28930	COG0745	RESPONSE REGULATOR receiver
SL103_RS28945	COG0183	Belongs to the thiolase family
SL103_RS29000	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SL103_RS29015	COG1250	3-hydroxyacyl-CoA dehydrogenase
SL103_RS29045	COG3850	Histidine kinase
SL103_RS29050	COG2197	response regulator
SL103_RS29060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SL103_RS29065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SL103_RS29070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SL103_RS29075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SL103_RS29080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SL103_RS29085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SL103_RS29090	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SL103_RS29110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SL103_RS29115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SL103_RS29125	COG2890	protein-(glutamine-N5) methyltransferase activity
SL103_RS29130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SL103_RS29135	COG0254	rRNA binding
SL103_RS29150	COG0083	homoserine kinase activity
SL103_RS29155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SL103_RS29160	COG0460	homoserine dehydrogenase
SL103_RS29165	COG0019	diaminopimelate decarboxylase activity
SL103_RS29170	COG0018	arginyl-trna synthetase
SL103_RS29185	COG2124	cytochrome p450
SL103_RS29190	COG0772	Belongs to the SEDS family
SL103_RS29195	COG0768	penicillin binding
SL103_RS29205	COG1119	ATPase activity
SL103_RS29280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SL103_RS29285	COG1357	PFAM Pentapeptide repeats (8 copies)
SL103_RS29305	COG0745	RESPONSE REGULATOR receiver
SL103_RS29310	COG2205	protein histidine kinase activity
SL103_RS29315	COG0567	Dehydrogenase, E1 component
SL103_RS29315	COG0508	dehydrogenase complex catalyzes the overall conversion of
SL103_RS29340	COG2255	four-way junction helicase activity
SL103_RS29395	COG0604	alcohol dehydrogenase
SL103_RS29400	COG0281	malic enzyme
SL103_RS29415	COG1126	abc transporter atp-binding protein
SL103_RS29420	COG4106	trans-aconitate 2-methyltransferase activity
SL103_RS29445	COG0513	Belongs to the DEAD box helicase family
SL103_RS29450	COG1278	Cold shock
SL103_RS29485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SL103_RS29490	COG1993	acr, cog1993
SL103_RS29495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SL103_RS29500	COG2186	Transcriptional regulator
SL103_RS29505	COG2807	transmembrane transport
SL103_RS29510	COG0598	Magnesium transport protein CorA
SL103_RS29515	COG0477	Major facilitator Superfamily
SL103_RS29530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SL103_RS29545	COG2066	Belongs to the glutaminase family
SL103_RS29600	COG1597	lipid kinase activity
SL103_RS29615	COG1309	transcriptional regulator
SL103_RS29620	COG1028	Short-chain dehydrogenase reductase Sdr
SL103_RS29625	COG0363	glucosamine-6-phosphate deaminase activity
SL103_RS29640	COG1472	Belongs to the glycosyl hydrolase 3 family
SL103_RS29645	COG0395	ABC-type sugar transport system, permease component
SL103_RS29650	COG1175	transmembrane transport
SL103_RS29655	COG2182	Extracellular solute-binding protein
SL103_RS29660	COG2188	Transcriptional regulator
SL103_RS29685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SL103_RS29690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SL103_RS29695	COG0242	peptide deformylase activity
SL103_RS29715	COG5662	AntiSigma factor
SL103_RS29720	COG1595	DNA-templated transcription, initiation
SL103_RS29725	COG1396	sequence-specific DNA binding
SL103_RS29725	COG3800	Transcriptional regulator
SL103_RS29735	COG2135	peptidase activity
SL103_RS29745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SL103_RS29755	COG2076	Multidrug Resistance protein
SL103_RS29765	COG0483	inositol monophosphate 1-phosphatase activity
SL103_RS29770	COG0517	IMP dehydrogenase activity
SL103_RS29770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SL103_RS29775	COG0753	catalase activity
SL103_RS29815	COG1615	UPF0182 protein
SL103_RS29825	COG3480	Lon protease (S16) C-terminal proteolytic domain
SL103_RS29880	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SL103_RS29920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SL103_RS29980	COG2267	carboxylic ester hydrolase activity
SL103_RS30025	COG1432	Conserved Protein
SL103_RS30030	COG2095	MarC family integral membrane protein
SL103_RS30035	COG0613	PHP domain protein
SL103_RS30045	COG2814	Major facilitator Superfamily
SL103_RS30055	COG0598	Magnesium transport protein CorA
SL103_RS30090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SL103_RS30095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SL103_RS30105	COG1595	DNA-templated transcription, initiation
SL103_RS30120	COG1024	Enoyl-CoA hydratase
SL103_RS30125	COG0519	Catalyzes the synthesis of GMP from XMP
SL103_RS30135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SL103_RS30140	COG1611	Belongs to the LOG family
SL103_RS30145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SL103_RS30170	COG0456	acetyltransferase
SL103_RS30185	COG2197	response regulator
SL103_RS30190	COG4585	Histidine kinase
SL103_RS30200	COG1131	(ABC) transporter
SL103_RS30215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SL103_RS30235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SL103_RS30240	COG4166	transmembrane transport
SL103_RS30250	COG0444	Belongs to the ABC transporter superfamily
SL103_RS30255	COG4608	Belongs to the ABC transporter superfamily
SL103_RS30265	COG4608	Belongs to the ABC transporter superfamily
SL103_RS30270	COG0444	Belongs to the ABC transporter superfamily
SL103_RS30275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SL103_RS30280	COG0601	transmembrane transport
SL103_RS30285	COG4166	transmembrane transport
SL103_RS30290	COG1217	gtp-binding protein TYPA
SL103_RS30345	COG0531	amino acid
SL103_RS30410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SL103_RS30420	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SL103_RS30470	COG0012	GTP binding
SL103_RS30480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SL103_RS30490	COG1570	exodeoxyribonuclease VII activity
SL103_RS30495	COG1722	exodeoxyribonuclease VII activity
SL103_RS30500	COG0778	Nitroreductase
SL103_RS30525	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SL103_RS30525	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SL103_RS30560	COG0114	fumarate hydratase activity
SL103_RS30605	COG1136	(ABC) transporter
SL103_RS30625	COG0450	alkyl hydroperoxide reductase
SL103_RS30630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS30645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SL103_RS30650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SL103_RS30655	COG0667	Aldo Keto reductase
SL103_RS30670	COG0640	Transcriptional regulator
SL103_RS30685	COG2885	chlorophyll binding
SL103_RS30725	COG2894	cell division
SL103_RS30770	COG2610	gluconate transmembrane transporter activity
SL103_RS30775	COG0251	oxidation-reduction process
SL103_RS30780	COG1414	Transcriptional regulator
SL103_RS30795	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SL103_RS30820	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SL103_RS30835	COG0154	amidase activity
SL103_RS30860	COG1331	Highly conserved protein containing a thioredoxin domain
SL103_RS30875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SL103_RS30885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SL103_RS30900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SL103_RS30905	COG2255	four-way junction helicase activity
SL103_RS30930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SL103_RS30950	COG0604	alcohol dehydrogenase
SL103_RS30965	COG1113	amino acid transport
SL103_RS30980	COG4585	Histidine kinase
SL103_RS30985	COG2197	response regulator
SL103_RS31010	COG2986	histidine ammonia-lyase
SL103_RS31020	COG1024	Enoyl-CoA hydratase
SL103_RS31025	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SL103_RS31035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SL103_RS31045	COG0768	penicillin binding
SL103_RS31050	COG0424	maF-like protein
SL103_RS31060	COG0693	protein deglycase activity
SL103_RS31065	COG0515	serine threonine protein kinase
SL103_RS31065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SL103_RS31070	COG0515	serine threonine protein kinase
SL103_RS31070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SL103_RS31085	COG4770	biotin carboxylase activity
SL103_RS31120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SL103_RS31130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SL103_RS31135	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS31140	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS31160	COG1595	DNA-templated transcription, initiation
SL103_RS31165	COG0745	RESPONSE REGULATOR receiver
SL103_RS31170	COG2205	protein histidine kinase activity
SL103_RS31195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SL103_RS31220	COG0583	DNA-binding transcription factor activity
SL103_RS31225	COG2814	Major facilitator Superfamily
SL103_RS31245	COG1079	Belongs to the binding-protein-dependent transport system permease family
SL103_RS31250	COG4603	Belongs to the binding-protein-dependent transport system permease family
SL103_RS31255	COG3845	ABC transporter
SL103_RS31260	COG1744	ABC transporter substrate-binding protein PnrA-like
SL103_RS31265	COG1473	amidohydrolase
SL103_RS31265	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SL103_RS31275	COG2089	acid synthase
SL103_RS31290	COG1216	Glycosyl transferase, family 2
SL103_RS31300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SL103_RS31320	COG3265	gluconokinase activity
SL103_RS31325	COG2186	Transcriptional regulator
SL103_RS31335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SL103_RS31335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SL103_RS31350	COG1595	DNA-templated transcription, initiation
SL103_RS31355	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SL103_RS31365	COG2009	succinate dehydrogenase
SL103_RS31380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SL103_RS31445	COG1408	metallophosphoesterase
SL103_RS31460	COG1686	Belongs to the peptidase S11 family
SL103_RS31465	COG1295	ribonuclease BN
SL103_RS31475	COG0180	Tryptophanyl-tRNA synthetase
SL103_RS31480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SL103_RS31485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SL103_RS31490	COG0754	glutathionylspermidine amidase activity
SL103_RS31510	COG0456	acetyltransferase
SL103_RS31515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SL103_RS31520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS31525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS31535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SL103_RS31540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SL103_RS31565	COG4176	ABC-type proline glycine betaine transport system permease component
SL103_RS31570	COG4175	Glycine betaine
SL103_RS31570	COG0517	IMP dehydrogenase activity
SL103_RS31580	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS31600	COG0039	L-malate dehydrogenase activity
SL103_RS31630	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SL103_RS31645	COG0138	bifunctional purine biosynthesis protein purh
SL103_RS31675	COG0045	succinate-CoA ligase (ADP-forming) activity
SL103_RS31690	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SL103_RS31695	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SL103_RS31700	COG0714	Associated with various cellular activities
SL103_RS31715	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SL103_RS31745	COG0791	NLP P60 protein
SL103_RS31755	COG2197	response regulator
SL103_RS31765	COG0515	serine threonine protein kinase
SL103_RS31765	COG2815	serine threonine protein kinase
SL103_RS31810	COG2084	Dehydrogenase
SL103_RS31815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SL103_RS31815	COG0519	Catalyzes the synthesis of GMP from XMP
SL103_RS31835	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS31840	COG0515	serine threonine protein kinase
SL103_RS31860	COG4585	Histidine kinase
SL103_RS31910	COG1131	(ABC) transporter
SL103_RS31935	COG0596	Alpha beta hydrolase
SL103_RS31935	COG2945	thiolester hydrolase activity
SL103_RS31945	COG4821	SIS domain
SL103_RS31955	COG0259	pyridoxamine-phosphate oxidase activity
SL103_RS31985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SL103_RS32000	COG5006	permease, DMT superfamily
SL103_RS32005	COG0583	DNA-binding transcription factor activity
SL103_RS32010	COG0277	FAD linked oxidase domain protein
SL103_RS32010	COG0247	lactate metabolic process
SL103_RS32020	COG2378	regulation of single-species biofilm formation
SL103_RS32025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SL103_RS32040	COG0667	Aldo Keto reductase
SL103_RS32065	COG2252	PERMEase
SL103_RS32075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SL103_RS32115	COG2814	Major facilitator Superfamily
SL103_RS32125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SL103_RS32130	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SL103_RS32135	COG1278	Cold shock
SL103_RS32160	COG1061	Type III restriction enzyme res subunit
SL103_RS32175	COG3973	AAA domain
SL103_RS32185	COG2814	Major facilitator Superfamily
SL103_RS32220	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SL103_RS32225	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SL103_RS32230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SL103_RS32230	COG1263	PTS System
SL103_RS32250	COG1278	Cold shock
SL103_RS32265	COG0463	Glycosyl transferase, family 2
SL103_RS32270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SL103_RS32300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SL103_RS32330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SL103_RS32360	COG2197	response regulator
SL103_RS32410	COG3842	ATPase activity
SL103_RS32420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SL103_RS32435	COG0215	cysteine-tRNA ligase activity
SL103_RS32440	COG3467	pyridoxamine 5'-phosphate
SL103_RS32445	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SL103_RS32450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SL103_RS32455	COG1329	Transcriptional regulator
SL103_RS32470	COG5002	protein histidine kinase activity
SL103_RS32490	COG2226	methyltransferase
SL103_RS32510	COG0588	phosphoglycerate mutase activity
SL103_RS32540	COG4106	trans-aconitate 2-methyltransferase activity
SL103_RS32545	COG0492	ferredoxin-NADP+ reductase activity
SL103_RS32555	COG0438	transferase activity, transferring glycosyl groups
SL103_RS32600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SL103_RS32625	COG0456	acetyltransferase
SL103_RS32630	COG0737	Belongs to the 5'-nucleotidase family
SL103_RS32635	COG0702	epimerase
SL103_RS32645	COG2972	Histidine kinase
SL103_RS32645	COG2205	protein histidine kinase activity
SL103_RS32650	COG0745	RESPONSE REGULATOR receiver
SL103_RS32655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SL103_RS32660	COG1609	Transcriptional regulator
SL103_RS32665	COG0745	RESPONSE REGULATOR receiver
SL103_RS32710	COG2897	thiosulfate sulfurtransferase activity
SL103_RS32730	COG3485	protocatechuate 3,4-dioxygenase
SL103_RS32735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SL103_RS32740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SL103_RS32750	COG0735	belongs to the Fur family
SL103_RS32760	COG1490	D-aminoacyl-tRNA deacylase activity
SL103_RS32795	COG1733	regulation of RNA biosynthetic process
SL103_RS32810	COG0583	DNA-binding transcription factor activity
SL103_RS32835	COG0667	Aldo Keto reductase
SL103_RS32850	COG2890	protein-(glutamine-N5) methyltransferase activity
SL103_RS32865	COG2378	regulation of single-species biofilm formation
SL103_RS32870	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SL103_RS32875	COG4988	ABC transporter
SL103_RS32885	COG1271	oxidase subunit
SL103_RS32935	COG0581	inorganic phosphate transmembrane transporter activity
SL103_RS32940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SL103_RS32945	COG0306	phosphate transporter
SL103_RS32955	COG1937	Protein conserved in bacteria
SL103_RS32970	COG0277	FAD linked oxidase domain protein
SL103_RS32975	COG0671	phosphoesterase, PA-phosphatase related
SL103_RS32980	COG1196	nuclear chromosome segregation
SL103_RS32980	COG0739	heme binding
SL103_RS32980	COG0741	lytic transglycosylase activity
SL103_RS33035	COG0180	Tryptophanyl-tRNA synthetase
SL103_RS33040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SL103_RS33050	COG0842	Transport permease protein
SL103_RS33050	COG1129	ABC transporter
SL103_RS33095	COG0515	serine threonine protein kinase
SL103_RS33095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SL103_RS33130	COG0129	dihydroxy-acid dehydratase activity
SL103_RS33140	COG1082	Xylose isomerase domain protein TIM barrel
SL103_RS33145	COG0248	Ppx GppA phosphatase
SL103_RS33165	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SL103_RS33180	COG0671	phosphoesterase, PA-phosphatase related
SL103_RS33190	COG1194	a g-specific adenine glycosylase
SL103_RS33195	COG1595	DNA-templated transcription, initiation
SL103_RS33205	COG0745	RESPONSE REGULATOR receiver
SL103_RS33210	COG2205	protein histidine kinase activity
SL103_RS33225	COG0739	heme binding
SL103_RS33250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SL103_RS33270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SL103_RS33280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SL103_RS33285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SL103_RS33305	COG0640	Transcriptional regulator
SL103_RS33315	COG2197	response regulator
SL103_RS33330	COG0649	NAD binding
SL103_RS33345	COG1174	glycine betaine transport
SL103_RS33350	COG1174	glycine betaine transport
SL103_RS33355	COG1125	glycine betaine transport
SL103_RS33355	COG0517	IMP dehydrogenase activity
SL103_RS33365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SL103_RS33370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SL103_RS33385	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SL103_RS33385	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SL103_RS33395	COG0302	gtp cyclohydrolase
SL103_RS33410	COG0037	tRNA processing
SL103_RS33420	COG2027	D-alanyl-D-alanine carboxypeptidase
SL103_RS33425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SL103_RS33440	COG0393	Putative heavy-metal-binding
SL103_RS33450	COG0655	NAD(P)H dehydrogenase (quinone) activity
SL103_RS33455	COG0076	glutamate decarboxylase activity
SL103_RS33465	COG2318	DinB family
SL103_RS33470	COG1012	belongs to the aldehyde dehydrogenase family
SL103_RS33490	COG0254	rRNA binding
SL103_RS33495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SL103_RS33510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SL103_RS33510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SL103_RS33545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SL103_RS33545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SL103_RS33570	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SL103_RS33575	COG3594	Acyltransferase
SL103_RS33580	COG0584	glycerophosphoryl diester phosphodiesterase
SL103_RS33600	COG0702	epimerase
SL103_RS33605	COG1846	Transcriptional regulator
SL103_RS33620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SL103_RS33625	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SL103_RS33630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SL103_RS33630	COG1754	DNA topoisomerase type I activity
SL103_RS33655	COG2890	protein-(glutamine-N5) methyltransferase activity
SL103_RS33665	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SL103_RS33670	COG2172	sigma factor antagonist activity
SL103_RS33675	COG1366	Belongs to the anti-sigma-factor antagonist family
SL103_RS33680	COG1205	dead DEAH box helicase
SL103_RS33680	COG1111	helicase
SL103_RS33735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SL103_RS33740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SL103_RS33750	COG2267	carboxylic ester hydrolase activity
SL103_RS33800	COG0003	Pfam Anion-transporting ATPase
SL103_RS33820	COG1408	metallophosphoesterase
SL103_RS33850	COG4249	Peptidase C14 caspase catalytic subunit p20
SL103_RS33850	COG2319	Wd-40 repeat
SL103_RS33890	COG0463	Glycosyl transferase, family 2
SL103_RS33945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SL103_RS33950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SL103_RS33970	COG2197	response regulator
SL103_RS33975	COG4585	Histidine kinase
SL103_RS34005	COG1309	transcriptional regulator
SL103_RS34045	COG1595	DNA-templated transcription, initiation
SL103_RS34065	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SL103_RS34070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SL103_RS34125	COG4980	gas vesicle protein
SL103_RS34125	COG1674	ftsk spoiiie
SL103_RS34220	COG1674	ftsk spoiiie
SL103_RS34220	COG4980	gas vesicle protein
SL103_RS34310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SL103_RS34315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SL103_RS34335	COG1132	(ABC) transporter
SL103_RS34340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SL103_RS34350	COG3631	Ketosteroid isomerase-related protein
SL103_RS34355	COG0702	epimerase
SL103_RS34370	COG0569	domain protein
SL103_RS34370	COG0189	ligase activity
SL103_RS34380	COG0402	S-adenosylhomocysteine deaminase activity
SL103_RS34385	COG0477	Major facilitator Superfamily
SL103_RS34400	COG1834	amidinotransferase
SL103_RS34405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SL103_RS34495	COG2030	dehydratase
SL103_RS34505	COG0477	Major facilitator Superfamily
SL103_RS34525	COG2268	Band 7 protein
SL103_RS34565	COG1064	alcohol dehydrogenase
SL103_RS34570	COG2409	Drug exporters of the RND superfamily
SL103_RS34615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SL103_RS34630	COG0590	tRNA wobble adenosine to inosine editing
SL103_RS34655	COG1191	sigma factor activity
SL103_RS34660	COG1191	sigma factor activity
SL103_RS34675	COG4221	oxidoreductase activity
SL103_RS34700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SL103_RS34725	COG0477	Major facilitator Superfamily
SL103_RS34750	COG0477	Major facilitator Superfamily
SL103_RS34755	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SL103_RS34755	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SL103_RS34765	COG2205	protein histidine kinase activity
SL103_RS34770	COG0745	RESPONSE REGULATOR receiver
SL103_RS34800	COG2249	NAD(P)H dehydrogenase (quinone) activity
SL103_RS34840	COG0494	nUDIX hydrolase
SL103_RS34865	COG2188	Transcriptional regulator
SL103_RS34930	COG0784	Response regulator, receiver
SL103_RS34935	COG0318	PFAM AMP-dependent synthetase and ligase
SL103_RS34950	COG4999	Histidine kinase
SL103_RS34950	COG3850	Histidine kinase
SL103_RS34950	COG2205	protein histidine kinase activity
SL103_RS34950	COG3437	response regulator, receiver
SL103_RS34955	COG3437	response regulator, receiver
SL103_RS35005	COG1595	DNA-templated transcription, initiation
SL103_RS35045	COG5632	N-Acetylmuramoyl-L-alanine amidase
SL103_RS35045	COG3409	Peptidoglycan-binding domain 1 protein
SL103_RS35090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SL103_RS35105	COG0653	protein targeting
SL103_RS35125	COG0006	proline dipeptidase activity
SL103_RS35160	COG2372	response to copper ion
SL103_RS35165	COG2837	iron assimilation
SL103_RS35170	COG0077	Prephenate dehydratase
SL103_RS35175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SL103_RS35180	COG0561	phosphatase activity
SL103_RS35200	COG0789	Transcriptional regulator
SL103_RS35215	COG2186	Transcriptional regulator
SL103_RS35220	COG2807	transmembrane transport
SL103_RS35245	COG1131	(ABC) transporter
SL103_RS35260	COG0789	Transcriptional regulator
SL103_RS35265	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SL103_RS35280	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SL103_RS35290	COG0501	Belongs to the peptidase M48B family
SL103_RS35300	COG0561	phosphatase activity
SL103_RS35310	COG4988	ABC transporter
SL103_RS35315	COG1294	oxidase, subunit
SL103_RS35320	COG1271	oxidase subunit
SL103_RS35330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SL103_RS35335	COG1609	Transcriptional regulator
SL103_RS35340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SL103_RS35350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SL103_RS35375	COG0662	Cupin 2, conserved barrel domain protein
SL103_RS35380	COG1950	PFAM Membrane protein of
SL103_RS35385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SL103_RS35390	COG0626	cystathionine gamma-synthase activity
SL103_RS35400	COG0494	nUDIX hydrolase
SL103_RS35435	COG2814	Major facilitator Superfamily
SL103_RS35440	COG1846	Transcriptional regulator
SL103_RS35470	COG4978	Transcriptional regulator
SL103_RS35470	COG0789	Transcriptional regulator
SL103_RS35480	COG0305	Participates in initiation and elongation during chromosome replication
SL103_RS35485	COG0534	Mate efflux family protein
SL103_RS35495	COG0359	binds to the 23S rRNA
SL103_RS35500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SL103_RS35505	COG0629	single-stranded DNA binding
SL103_RS35510	COG0360	Binds together with S18 to 16S ribosomal RNA
SL103_RS35535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SL103_RS35560	COG0617	tRNA 3'-terminal CCA addition
SL103_RS35570	COG0728	peptidoglycan biosynthetic process
SL103_RS35575	COG0515	serine threonine protein kinase
SL103_RS35575	COG2815	serine threonine protein kinase
SL103_RS35580	COG1595	DNA-templated transcription, initiation
SL103_RS35590	COG0492	ferredoxin-NADP+ reductase activity
SL103_RS35595	COG3118	belongs to the thioredoxin family
SL103_RS35610	COG1192	Involved in chromosome partitioning
SL103_RS35615	COG0357	Ribosomal RNA small subunit methyltransferase G
SL103_RS35620	COG1847	R3H domain protein
SL103_RS35625	COG0706	membrane insertase activity
SL103_RS35630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SL103_RS35640	COG0230	Belongs to the bacterial ribosomal protein bL34 family