locus-tag	class	description
BXT88_RS00045	COG1819	glycosyl
BXT88_RS00085	COG1819	glycosyl
BXT88_RS00090	COG0789	Transcriptional regulator
BXT88_RS00130	COG1309	transcriptional regulator
BXT88_RS00190	COG1132	(ABC) transporter
BXT88_RS00225	COG0028	Belongs to the TPP enzyme family
BXT88_RS00235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXT88_RS00240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXT88_RS00270	COG2826	transposase and inactivated derivatives, IS30 family
BXT88_RS00310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXT88_RS00370	COG0137	argininosuccinate synthase activity
BXT88_RS00430	COG1733	regulation of RNA biosynthetic process
BXT88_RS00445	COG1959	2 iron, 2 sulfur cluster binding
BXT88_RS00450	COG1017	nitric oxide dioxygenase activity
BXT88_RS00450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BXT88_RS00485	COG4221	oxidoreductase activity
BXT88_RS00500	COG1349	DNA-binding transcription factor activity
BXT88_RS00505	COG1063	alcohol dehydrogenase
BXT88_RS00510	COG2814	Major facilitator Superfamily
BXT88_RS00520	COG4941	Belongs to the sigma-70 factor family
BXT88_RS00525	COG3795	YCII-related domain
BXT88_RS00550	COG4585	Histidine kinase
BXT88_RS00555	COG2197	response regulator
BXT88_RS00590	COG2301	Belongs to the HpcH HpaI aldolase family
BXT88_RS00610	COG2814	Major facilitator Superfamily
BXT88_RS00615	COG0583	DNA-binding transcription factor activity
BXT88_RS00640	COG1271	oxidase subunit
BXT88_RS00665	COG3321	synthase
BXT88_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS00665	COG0604	alcohol dehydrogenase
BXT88_RS00680	COG2318	DinB family
BXT88_RS00700	COG3387	PFAM Glycoside hydrolase 15-related
BXT88_RS00710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BXT88_RS00720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXT88_RS00730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXT88_RS00735	COG2409	Drug exporters of the RND superfamily
BXT88_RS00765	COG0181	hydroxymethylbilane synthase activity
BXT88_RS00775	COG0477	Major facilitator Superfamily
BXT88_RS00795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BXT88_RS00810	COG1794	racemase activity, acting on amino acids and derivatives
BXT88_RS00855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXT88_RS00870	COG0456	acetyltransferase
BXT88_RS00885	COG1309	transcriptional regulator
BXT88_RS00905	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BXT88_RS00945	COG3903	Transcriptional regulator
BXT88_RS00945	COG2197	response regulator
BXT88_RS00985	COG1132	(ABC) transporter
BXT88_RS00995	COG4221	oxidoreductase activity
BXT88_RS01015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXT88_RS01045	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BXT88_RS01090	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS01100	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXT88_RS01115	COG4310	Domain of unknown function (DUF2172)
BXT88_RS01125	COG1215	transferase activity, transferring glycosyl groups
BXT88_RS01140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BXT88_RS01240	COG3387	PFAM Glycoside hydrolase 15-related
BXT88_RS01250	COG1597	lipid kinase activity
BXT88_RS01295	COG3631	Ketosteroid isomerase-related protein
BXT88_RS01300	COG0702	epimerase
BXT88_RS01315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXT88_RS01320	COG4221	oxidoreductase activity
BXT88_RS01330	COG0306	phosphate transporter
BXT88_RS01340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXT88_RS01460	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BXT88_RS01525	COG3293	Transposase
BXT88_RS01550	COG4941	Belongs to the sigma-70 factor family
BXT88_RS01555	COG3795	YCII-related domain
BXT88_RS01570	COG1733	regulation of RNA biosynthetic process
BXT88_RS01610	COG0346	lactoylglutathione lyase activity
BXT88_RS01675	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BXT88_RS01675	COG0778	Nitroreductase
BXT88_RS01685	COG1309	transcriptional regulator
BXT88_RS01695	COG5433	transposase activity
BXT88_RS01775	COG3594	Acyltransferase
BXT88_RS01780	COG1733	regulation of RNA biosynthetic process
BXT88_RS01785	COG0702	epimerase
BXT88_RS01805	COG0515	serine threonine protein kinase
BXT88_RS01805	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXT88_RS01830	COG2124	cytochrome p450
BXT88_RS01830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BXT88_RS01850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXT88_RS01910	COG0596	Alpha beta hydrolase
BXT88_RS01935	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS01935	COG3321	synthase
BXT88_RS01935	COG0604	alcohol dehydrogenase
BXT88_RS01955	COG0148	phosphopyruvate hydratase activity
BXT88_RS01960	COG4977	sequence-specific DNA binding
BXT88_RS01990	COG0640	Transcriptional regulator
BXT88_RS02030	COG0657	acetylesterase activity
BXT88_RS02075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS02095	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BXT88_RS02130	COG0477	Major facilitator Superfamily
BXT88_RS02140	COG1132	(ABC) transporter
BXT88_RS02200	COG0456	acetyltransferase
BXT88_RS02220	COG0302	gtp cyclohydrolase
BXT88_RS02250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BXT88_RS02255	COG2197	response regulator
BXT88_RS02270	COG4552	Acetyltransferase involved in intracellular survival and related
BXT88_RS02295	COG5006	permease, DMT superfamily
BXT88_RS02305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BXT88_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS02385	COG0583	DNA-binding transcription factor activity
BXT88_RS02390	COG2814	Major facilitator Superfamily
BXT88_RS02440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXT88_RS02455	COG4948	Mandelate Racemase Muconate Lactonizing
BXT88_RS02465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXT88_RS02485	COG2508	Transcriptional regulator
BXT88_RS02485	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BXT88_RS02490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BXT88_RS02500	COG0483	inositol monophosphate 1-phosphatase activity
BXT88_RS02520	COG2197	response regulator
BXT88_RS02525	COG3851	Histidine kinase
BXT88_RS02540	COG1595	DNA-templated transcription, initiation
BXT88_RS02570	COG0028	Belongs to the TPP enzyme family
BXT88_RS02585	COG0300	oxidoreductase activity
BXT88_RS02615	COG1132	(ABC) transporter
BXT88_RS02625	COG1132	(ABC) transporter
BXT88_RS02625	COG2375	cellular response to nickel ion
BXT88_RS02665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXT88_RS02675	COG0590	tRNA wobble adenosine to inosine editing
BXT88_RS02690	COG0583	DNA-binding transcription factor activity
BXT88_RS02695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXT88_RS02705	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BXT88_RS02720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS02735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS02760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS02775	COG5343	regulation of RNA biosynthetic process
BXT88_RS02780	COG1595	DNA-templated transcription, initiation
BXT88_RS02785	COG3290	protein histidine kinase activity
BXT88_RS02825	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BXT88_RS02910	COG2010	Cytochrome c
BXT88_RS02910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BXT88_RS02930	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS02960	COG1414	Transcriptional regulator
BXT88_RS02990	COG4214	carbohydrate transport
BXT88_RS02995	COG3896	Chloramphenicol phosphotransferase-like protein
BXT88_RS03005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BXT88_RS03020	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS03030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BXT88_RS03050	COG2208	phosphoserine phosphatase activity
BXT88_RS03050	COG2770	Histidine kinase
BXT88_RS03060	COG2172	sigma factor antagonist activity
BXT88_RS03065	COG1366	Belongs to the anti-sigma-factor antagonist family
BXT88_RS03070	COG1366	Belongs to the anti-sigma-factor antagonist family
BXT88_RS03080	COG1473	amidohydrolase
BXT88_RS03105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BXT88_RS03110	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS03125	COG0577	efflux transmembrane transporter activity
BXT88_RS03125	COG1136	(ABC) transporter
BXT88_RS03130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BXT88_RS03135	COG0693	protein deglycase activity
BXT88_RS03165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BXT88_RS03210	COG3629	intracellular signal transduction
BXT88_RS03210	COG3903	Transcriptional regulator
BXT88_RS03235	COG0069	glutamate synthase activity
BXT88_RS03240	COG0028	Belongs to the TPP enzyme family
BXT88_RS03245	COG1191	sigma factor activity
BXT88_RS03255	COG0784	Response regulator, receiver
BXT88_RS03260	COG4251	negative regulation of phosphorylation
BXT88_RS03290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXT88_RS03310	COG0531	amino acid
BXT88_RS03335	COG0596	Alpha beta hydrolase
BXT88_RS03350	COG3469	chitinase activity
BXT88_RS03370	COG1309	transcriptional regulator
BXT88_RS03390	COG0583	DNA-binding transcription factor activity
BXT88_RS03395	COG0504	CTP synthase activity
BXT88_RS03405	COG0515	serine threonine protein kinase
BXT88_RS03415	COG1132	(ABC) transporter
BXT88_RS03420	COG1132	(ABC) transporter
BXT88_RS03445	COG2197	response regulator
BXT88_RS03455	COG1720	tRNA m6t6A37 methyltransferase activity
BXT88_RS03465	COG1309	transcriptional regulator
BXT88_RS03470	COG2318	DinB family
BXT88_RS03525	COG0640	Transcriptional regulator
BXT88_RS03530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BXT88_RS03550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXT88_RS03560	COG0668	transmembrane transport
BXT88_RS03565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXT88_RS03570	COG2610	gluconate transmembrane transporter activity
BXT88_RS03575	COG4948	Mandelate Racemase Muconate Lactonizing
BXT88_RS03595	COG1129	ABC transporter
BXT88_RS03600	COG1172	Belongs to the binding-protein-dependent transport system permease family
BXT88_RS03635	COG0300	oxidoreductase activity
BXT88_RS03635	COG3321	synthase
BXT88_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS03635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS03635	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS03645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS03655	COG2017	converts alpha-aldose to the beta-anomer
BXT88_RS03675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS03695	COG2814	Major facilitator Superfamily
BXT88_RS03785	COG0009	L-threonylcarbamoyladenylate synthase
BXT88_RS03825	COG1733	regulation of RNA biosynthetic process
BXT88_RS03860	COG5634	Uncharacterized conserved protein (DUF2278)
BXT88_RS03865	COG0738	Major facilitator superfamily
BXT88_RS03880	COG2837	iron assimilation
BXT88_RS03905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXT88_RS03970	COG2239	Acts as a magnesium transporter
BXT88_RS03975	COG0517	IMP dehydrogenase activity
BXT88_RS03975	COG0516	GMP reductase activity
BXT88_RS03980	COG2326	polyphosphate kinase activity
BXT88_RS03985	COG0517	IMP dehydrogenase activity
BXT88_RS03985	COG0516	GMP reductase activity
BXT88_RS03990	COG2205	protein histidine kinase activity
BXT88_RS03995	COG0745	RESPONSE REGULATOR receiver
BXT88_RS04000	COG1017	nitric oxide dioxygenase activity
BXT88_RS04000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BXT88_RS04015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BXT88_RS04045	COG2890	protein-(glutamine-N5) methyltransferase activity
BXT88_RS04060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BXT88_RS04070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BXT88_RS04105	COG0697	spore germination
BXT88_RS04190	COG1968	undecaprenyl-diphosphatase activity
BXT88_RS04210	COG1113	amino acid transport
BXT88_RS04240	COG4213	ABC transporter substrate-binding protein
BXT88_RS04250	COG4214	carbohydrate transport
BXT88_RS04255	COG0701	Predicted permease
BXT88_RS04280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BXT88_RS04300	COG3938	Belongs to the proline racemase family
BXT88_RS04325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS04360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXT88_RS04365	COG1509	lysine 2,3-aminomutase activity
BXT88_RS04375	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXT88_RS04385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS04390	COG0477	Major facilitator Superfamily
BXT88_RS04395	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXT88_RS04430	COG0789	Transcriptional regulator
BXT88_RS04440	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS04450	COG1024	Enoyl-CoA hydratase
BXT88_RS04470	COG0183	Belongs to the thiolase family
BXT88_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS04480	COG1024	Enoyl-CoA hydratase
BXT88_RS04485	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS04510	COG2208	phosphoserine phosphatase activity
BXT88_RS04510	COG2770	Histidine kinase
BXT88_RS04515	COG1573	uracil-dna glycosylase
BXT88_RS04520	COG0542	response to heat
BXT88_RS04545	COG1864	DNA RNA non-specific endonuclease
BXT88_RS04545	COG3591	Belongs to the peptidase S1B family
BXT88_RS04580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXT88_RS04590	COG3290	protein histidine kinase activity
BXT88_RS04595	COG4565	transcriptional regulatory protein
BXT88_RS04600	COG2186	Transcriptional regulator
BXT88_RS04625	COG0640	Transcriptional regulator
BXT88_RS04640	COG0531	amino acid
BXT88_RS04645	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS04680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BXT88_RS04700	COG2268	Band 7 protein
BXT88_RS04765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXT88_RS04820	COG1959	2 iron, 2 sulfur cluster binding
BXT88_RS04825	COG1733	regulation of RNA biosynthetic process
BXT88_RS04840	COG2508	Transcriptional regulator
BXT88_RS04840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BXT88_RS04910	COG2207	Transcriptional regulator
BXT88_RS04910	COG1917	Cupin 2, conserved barrel domain protein
BXT88_RS04920	COG1120	ATPase activity
BXT88_RS04925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXT88_RS04935	COG1733	regulation of RNA biosynthetic process
BXT88_RS04940	COG0596	Alpha beta hydrolase
BXT88_RS04955	COG2274	protein secretion by the type I secretion system
BXT88_RS04970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BXT88_RS04970	COG1796	DNA polymerase
BXT88_RS04980	COG0583	DNA-binding transcription factor activity
BXT88_RS04985	COG0156	8-amino-7-oxononanoate synthase activity
BXT88_RS04990	COG1063	alcohol dehydrogenase
BXT88_RS05020	COG3387	PFAM Glycoside hydrolase 15-related
BXT88_RS05030	COG5001	Diguanylate cyclase
BXT88_RS05065	COG2318	DinB family
BXT88_RS05085	COG0745	RESPONSE REGULATOR receiver
BXT88_RS05090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BXT88_RS05090	COG1024	Enoyl-CoA hydratase
BXT88_RS05105	COG0477	Major facilitator Superfamily
BXT88_RS05145	COG3585	molybdate ion transport
BXT88_RS05155	COG3835	regulator
BXT88_RS05170	COG2814	Major facilitator Superfamily
BXT88_RS05205	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BXT88_RS05220	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BXT88_RS05230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXT88_RS05230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXT88_RS05310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXT88_RS05315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXT88_RS05340	COG0386	Belongs to the glutathione peroxidase family
BXT88_RS05350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXT88_RS05370	COG1132	(ABC) transporter
BXT88_RS05380	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BXT88_RS05410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BXT88_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS05490	COG0667	Aldo Keto reductase
BXT88_RS05505	COG0574	Belongs to the PEP-utilizing enzyme family
BXT88_RS05505	COG3848	Pyruvate phosphate dikinase
BXT88_RS05510	COG1819	glycosyl
BXT88_RS05515	COG1397	ADP-ribosylglycohydrolase
BXT88_RS05535	COG0640	Transcriptional regulator
BXT88_RS05540	COG0798	PFAM Bile acid sodium symporter
BXT88_RS05545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXT88_RS05550	COG2814	Major facilitator Superfamily
BXT88_RS05565	COG1595	DNA-templated transcription, initiation
BXT88_RS05605	COG2267	carboxylic ester hydrolase activity
BXT88_RS05610	COG1301	dicarboxylic acid transport
BXT88_RS05615	COG2828	Protein conserved in bacteria
BXT88_RS05655	COG2814	Major facilitator Superfamily
BXT88_RS05660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS05710	COG0789	Transcriptional regulator
BXT88_RS05725	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS05730	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BXT88_RS05730	COG0825	malonyl-CoA metabolic process
BXT88_RS05740	COG0583	DNA-binding transcription factor activity
BXT88_RS05745	COG0697	spore germination
BXT88_RS05810	COG0702	epimerase
BXT88_RS05845	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BXT88_RS05845	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BXT88_RS05855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BXT88_RS05895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXT88_RS05930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXT88_RS05940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXT88_RS05950	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BXT88_RS05955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BXT88_RS05970	COG0494	nUDIX hydrolase
BXT88_RS05980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BXT88_RS05985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BXT88_RS06000	COG0596	Alpha beta hydrolase
BXT88_RS06035	COG2146	nitrite reductase [NAD(P)H] activity
BXT88_RS06070	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BXT88_RS06090	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BXT88_RS06095	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BXT88_RS06100	COG1984	allophanate hydrolase subunit 2
BXT88_RS06115	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS06130	COG2226	methyltransferase
BXT88_RS06210	COG1024	Enoyl-CoA hydratase
BXT88_RS06240	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS06250	COG2070	2-Nitropropane dioxygenase
BXT88_RS06265	COG0515	serine threonine protein kinase
BXT88_RS06280	COG2080	2 iron, 2 sulfur cluster binding
BXT88_RS06280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BXT88_RS06290	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS06315	COG0243	molybdopterin cofactor binding
BXT88_RS06330	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BXT88_RS06350	COG1006	Multisubunit Na H antiporter MnhC subunit
BXT88_RS06355	COG0651	ATP synthesis coupled electron transport
BXT88_RS06365	COG1793	dna ligase
BXT88_RS06365	COG3285	dna ligase
BXT88_RS06380	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BXT88_RS06485	COG2376	Dihydroxyacetone kinase
BXT88_RS06490	COG1461	Dihydroxyacetone kinase
BXT88_RS06515	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS06560	COG0395	ABC-type sugar transport system, permease component
BXT88_RS06565	COG1063	alcohol dehydrogenase
BXT88_RS06575	COG1793	dna ligase
BXT88_RS06585	COG3224	Antibiotic biosynthesis monooxygenase
BXT88_RS06590	COG0590	tRNA wobble adenosine to inosine editing
BXT88_RS06605	COG1011	Hydrolase
BXT88_RS06660	COG1191	sigma factor activity
BXT88_RS06675	COG0494	nUDIX hydrolase
BXT88_RS06700	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS06720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BXT88_RS06740	COG0633	Ferredoxin
BXT88_RS06740	COG3217	Mosc domain protein beta barrel domain protein
BXT88_RS06760	COG0464	growth
BXT88_RS06770	COG1349	DNA-binding transcription factor activity
BXT88_RS06820	COG1940	carbohydrate kinase activity
BXT88_RS06825	COG2223	nitrite transmembrane transporter activity
BXT88_RS06835	COG2197	response regulator
BXT88_RS06840	COG4585	Histidine kinase
BXT88_RS06855	COG0445	tRNA wobble uridine modification
BXT88_RS06870	COG0395	ABC-type sugar transport system, permease component
BXT88_RS06885	COG3345	alpha-galactosidase
BXT88_RS06910	COG2318	DinB family
BXT88_RS06920	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BXT88_RS06975	COG0584	glycerophosphoryl diester phosphodiesterase
BXT88_RS06985	COG2197	response regulator
BXT88_RS07005	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BXT88_RS07030	COG2124	cytochrome p450
BXT88_RS07050	COG0017	Asparaginyl-tRNA synthetase
BXT88_RS07055	COG0069	glutamate synthase activity
BXT88_RS07105	COG2124	cytochrome p450
BXT88_RS07125	COG3321	synthase
BXT88_RS07125	COG0604	alcohol dehydrogenase
BXT88_RS07125	COG3321	synthase
BXT88_RS07125	COG0604	alcohol dehydrogenase
BXT88_RS07140	COG3321	synthase
BXT88_RS07140	COG0604	alcohol dehydrogenase
BXT88_RS07155	COG3321	synthase
BXT88_RS07155	COG0604	alcohol dehydrogenase
BXT88_RS07175	COG0604	alcohol dehydrogenase
BXT88_RS07175	COG3321	synthase
BXT88_RS07195	COG0604	alcohol dehydrogenase
BXT88_RS07195	COG3321	synthase
BXT88_RS07235	COG0671	phosphoesterase, PA-phosphatase related
BXT88_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS07340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BXT88_RS07345	COG0140	phosphoribosyl-ATP diphosphatase activity
BXT88_RS07350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BXT88_RS07355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BXT88_RS07355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BXT88_RS07360	COG3201	nicotinamide mononucleotide transporter
BXT88_RS07375	COG1090	epimerase
BXT88_RS07380	COG1846	Transcriptional regulator
BXT88_RS07380	COG1940	carbohydrate kinase activity
BXT88_RS07385	COG0738	Major facilitator superfamily
BXT88_RS07395	COG2233	PERMEase
BXT88_RS07415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXT88_RS07430	COG0477	Major facilitator Superfamily
BXT88_RS07440	COG0531	amino acid
BXT88_RS07460	COG2390	Transcriptional regulator
BXT88_RS07465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BXT88_RS07470	COG1846	Transcriptional regulator
BXT88_RS07485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BXT88_RS07500	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BXT88_RS07525	COG0284	orotidine-5'-phosphate decarboxylase activity
BXT88_RS07530	COG0167	dihydroorotate dehydrogenase activity
BXT88_RS07535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BXT88_RS07540	COG0505	Belongs to the CarA family
BXT88_RS07550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BXT88_RS07555	COG0540	Belongs to the ATCase OTCase family
BXT88_RS07560	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BXT88_RS07570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXT88_RS07575	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BXT88_RS07580	COG0006	proline dipeptidase activity
BXT88_RS07590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BXT88_RS07595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BXT88_RS07600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BXT88_RS07605	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BXT88_RS07610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BXT88_RS07620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BXT88_RS07625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BXT88_RS07645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BXT88_RS07665	COG0124	histidyl-tRNA synthetase
BXT88_RS07675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BXT88_RS07680	COG1196	nuclear chromosome segregation
BXT88_RS07685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXT88_RS07690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BXT88_RS07695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXT88_RS07700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXT88_RS07710	COG2255	four-way junction helicase activity
BXT88_RS07715	COG0632	four-way junction helicase activity
BXT88_RS07720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BXT88_RS07725	COG0217	transcriptional regulatory protein
BXT88_RS07730	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BXT88_RS07735	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BXT88_RS07745	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS07750	COG1560	Kdo2-lipid A biosynthetic process
BXT88_RS07755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BXT88_RS07790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BXT88_RS07805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXT88_RS07850	COG0456	acetyltransferase
BXT88_RS07860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXT88_RS07915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXT88_RS07915	COG1648	precorrin-2 dehydrogenase activity
BXT88_RS07920	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BXT88_RS07935	COG1464	Belongs to the NlpA lipoprotein family
BXT88_RS07940	COG2011	ABC-type metal ion transport system permease component
BXT88_RS07945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BXT88_RS07970	COG0584	glycerophosphoryl diester phosphodiesterase
BXT88_RS07985	COG0477	Major facilitator Superfamily
BXT88_RS07995	COG0165	Argininosuccinate lyase
BXT88_RS08000	COG0137	argininosuccinate synthase activity
BXT88_RS08015	COG1438	arginine binding
BXT88_RS08020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BXT88_RS08025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BXT88_RS08030	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BXT88_RS08035	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BXT88_RS08095	COG0697	spore germination
BXT88_RS08105	COG1649	PFAM Uncharacterised BCR, COG1649
BXT88_RS08145	COG1051	belongs to the nudix hydrolase family
BXT88_RS08160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXT88_RS08160	COG0072	phenylalanine-tRNA ligase activity
BXT88_RS08165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BXT88_RS08170	COG5002	protein histidine kinase activity
BXT88_RS08175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXT88_RS08180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BXT88_RS08185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BXT88_RS08190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BXT88_RS08200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BXT88_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS08240	COG0174	glutamine synthetase
BXT88_RS08245	COG2186	Transcriptional regulator
BXT88_RS08250	COG0531	amino acid
BXT88_RS08255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BXT88_RS08290	COG0517	IMP dehydrogenase activity
BXT88_RS08290	COG4175	Glycine betaine
BXT88_RS08295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXT88_RS08325	COG3254	rhamnose metabolic process
BXT88_RS08330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS08340	COG0805	protein transport
BXT88_RS08345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXT88_RS08365	COG2378	regulation of single-species biofilm formation
BXT88_RS08375	COG0544	peptidyl-prolyl cis-trans isomerase activity
BXT88_RS08380	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BXT88_RS08390	COG1609	Transcriptional regulator
BXT88_RS08395	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BXT88_RS08400	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BXT88_RS08410	COG4122	O-methyltransferase activity
BXT88_RS08415	COG1222	aaa ATPase
BXT88_RS08440	COG1994	Peptidase M50
BXT88_RS08440	COG0517	IMP dehydrogenase activity
BXT88_RS08450	COG2197	response regulator
BXT88_RS08460	COG4166	transmembrane transport
BXT88_RS08465	COG0546	phosphoglycolate phosphatase activity
BXT88_RS08470	COG0646	methionine synthase
BXT88_RS08470	COG1410	methionine synthase
BXT88_RS08475	COG1414	Transcriptional regulator
BXT88_RS08480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BXT88_RS08485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BXT88_RS08490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BXT88_RS08500	COG2186	Transcriptional regulator
BXT88_RS08525	COG1129	ABC transporter
BXT88_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS08540	COG4948	Mandelate Racemase Muconate Lactonizing
BXT88_RS08550	COG0215	cysteine-tRNA ligase activity
BXT88_RS08570	COG0598	Magnesium transport protein CorA
BXT88_RS08580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS08585	COG0667	Aldo Keto reductase
BXT88_RS08615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXT88_RS08640	COG0488	(ABC) transporter
BXT88_RS08645	COG2124	cytochrome p450
BXT88_RS08655	COG0745	RESPONSE REGULATOR receiver
BXT88_RS08660	COG5002	protein histidine kinase activity
BXT88_RS08700	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BXT88_RS08705	COG2149	membrane
BXT88_RS08730	COG1309	transcriptional regulator
BXT88_RS08735	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS08745	COG3876	Protein conserved in bacteria
BXT88_RS08760	COG1819	glycosyl
BXT88_RS08765	COG0477	Major facilitator Superfamily
BXT88_RS08835	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS08850	COG0477	Major facilitator Superfamily
BXT88_RS08875	COG2851	Citrate transporter
BXT88_RS08880	COG0243	molybdopterin cofactor binding
BXT88_RS08885	COG1309	transcriptional regulator
BXT88_RS08890	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BXT88_RS08895	COG2188	Transcriptional regulator
BXT88_RS08900	COG0583	DNA-binding transcription factor activity
BXT88_RS08905	COG2329	Antibiotic biosynthesis monooxygenase
BXT88_RS08910	COG2814	Major facilitator Superfamily
BXT88_RS08910	COG0477	Major facilitator Superfamily
BXT88_RS08945	COG0463	Glycosyl transferase, family 2
BXT88_RS08965	COG3664	PFAM glycoside hydrolase family 39
BXT88_RS08975	COG1254	Belongs to the acylphosphatase family
BXT88_RS09015	COG1834	amidinotransferase
BXT88_RS09020	COG1725	Transcriptional regulator
BXT88_RS09035	COG2264	protein methyltransferase activity
BXT88_RS09040	COG0583	DNA-binding transcription factor activity
BXT88_RS09060	COG1522	sequence-specific DNA binding
BXT88_RS09065	COG0531	amino acid
BXT88_RS09085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BXT88_RS09090	COG0587	DNA-directed DNA polymerase activity
BXT88_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS09125	COG0330	HflC and HflK could
BXT88_RS09145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS09150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXT88_RS09155	COG1126	abc transporter atp-binding protein
BXT88_RS09170	COG0765	amino acid transport
BXT88_RS09180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXT88_RS09185	COG1799	cell septum assembly
BXT88_RS09190	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS09195	COG0477	Major facilitator Superfamily
BXT88_RS09205	COG0671	phosphoesterase, PA-phosphatase related
BXT88_RS09225	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS09230	COG3583	domain protein
BXT88_RS09245	COG1160	GTP binding
BXT88_RS09255	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BXT88_RS09285	COG1187	pseudouridine synthase activity
BXT88_RS09290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BXT88_RS09295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BXT88_RS09310	COG0686	Belongs to the AlaDH PNT family
BXT88_RS09320	COG0494	nUDIX hydrolase
BXT88_RS09325	COG0504	CTP synthase activity
BXT88_RS09330	COG3387	PFAM Glycoside hydrolase 15-related
BXT88_RS09370	COG0497	DNA recombination
BXT88_RS09380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BXT88_RS09400	COG1120	ATPase activity
BXT88_RS09405	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXT88_RS09410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXT88_RS09425	COG0647	UMP catabolic process
BXT88_RS09440	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BXT88_RS09480	COG2094	Belongs to the DNA glycosylase MPG family
BXT88_RS09490	COG1881	PFAM PEBP family protein
BXT88_RS09515	COG1119	ATPase activity
BXT88_RS09535	COG2197	response regulator
BXT88_RS09540	COG4585	Histidine kinase
BXT88_RS09550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BXT88_RS09565	COG0842	Transport permease protein
BXT88_RS09565	COG1716	ATPase activity
BXT88_RS09565	COG1131	(ABC) transporter
BXT88_RS09570	COG0560	Phosphoserine phosphatase
BXT88_RS09570	COG3830	Belongs to the UPF0237 family
BXT88_RS09590	COG2186	Transcriptional regulator
BXT88_RS09595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BXT88_RS09600	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS09615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BXT88_RS09620	COG2261	transglycosylase associated protein
BXT88_RS09635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BXT88_RS09640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXT88_RS09655	COG1404	Belongs to the peptidase S8 family
BXT88_RS09675	COG3340	Belongs to the peptidase S51 family
BXT88_RS09680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BXT88_RS09695	COG3387	PFAM Glycoside hydrolase 15-related
BXT88_RS09725	COG1302	Protein conserved in bacteria
BXT88_RS09745	COG0488	(ABC) transporter
BXT88_RS09770	COG0235	Class ii aldolase
BXT88_RS09785	COG1653	transport
BXT88_RS09800	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BXT88_RS09805	COG1492	cobalamin metabolic process
BXT88_RS09820	COG1797	cobyrinic acid a,c-diamide synthase activity
BXT88_RS09835	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BXT88_RS09860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BXT88_RS09865	COG1917	Cupin 2, conserved barrel domain protein
BXT88_RS09880	COG1902	pentaerythritol trinitrate reductase activity
BXT88_RS09910	COG1414	Transcriptional regulator
BXT88_RS09920	COG4585	Histidine kinase
BXT88_RS09935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXT88_RS09940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXT88_RS09955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS09980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXT88_RS09990	COG2171	N-acyltransferase activity
BXT88_RS09995	COG2076	Multidrug Resistance protein
BXT88_RS10000	COG2151	metal-sulfur cluster biosynthetic enzyme
BXT88_RS10005	COG0822	iron-sulfur transferase activity
BXT88_RS10010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXT88_RS10015	COG0396	ATPase activity
BXT88_RS10025	COG0719	Fe-S assembly protein
BXT88_RS10040	COG1131	(ABC) transporter
BXT88_RS10065	COG0109	protoheme IX farnesyltransferase activity
BXT88_RS10070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BXT88_RS10075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BXT88_RS10090	COG0363	glucosamine-6-phosphate deaminase activity
BXT88_RS10095	COG0166	Belongs to the GPI family
BXT88_RS10105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BXT88_RS10110	COG0149	triose-phosphate isomerase activity
BXT88_RS10115	COG0126	phosphoglycerate kinase activity
BXT88_RS10120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BXT88_RS10125	COG1481	regulation of sporulation
BXT88_RS10130	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BXT88_RS10135	COG1660	Displays ATPase and GTPase activities
BXT88_RS10140	COG0322	excinuclease ABC activity
BXT88_RS10165	COG1609	Transcriptional regulator
BXT88_RS10175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BXT88_RS10215	COG0556	nucleotide-excision repair
BXT88_RS10220	COG0584	glycerophosphoryl diester phosphodiesterase
BXT88_RS10225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BXT88_RS10275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BXT88_RS10300	COG0237	dephospho-CoA kinase activity
BXT88_RS10325	COG2226	methyltransferase
BXT88_RS10330	COG1643	Atp-dependent helicase
BXT88_RS10365	COG2050	protein possibly involved in aromatic compounds catabolism
BXT88_RS10375	COG0559	Belongs to the binding-protein-dependent transport system permease family
BXT88_RS10420	COG0737	Belongs to the 5'-nucleotidase family
BXT88_RS10455	COG1470	cell adhesion involved in biofilm formation
BXT88_RS10455	COG0366	Alpha amylase catalytic
BXT88_RS10485	COG0596	Alpha beta hydrolase
BXT88_RS10495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXT88_RS10505	COG3467	pyridoxamine 5'-phosphate
BXT88_RS10510	COG0640	Transcriptional regulator
BXT88_RS10525	COG0070	glutamate synthase
BXT88_RS10525	COG0069	glutamate synthase activity
BXT88_RS10525	COG0067	glutamate synthase
BXT88_RS10555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BXT88_RS10565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BXT88_RS10575	COG0159	tryptophan synthase activity
BXT88_RS10580	COG0133	tryptophan synthase activity
BXT88_RS10590	COG0134	indole-3-glycerol-phosphate synthase activity
BXT88_RS10610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXT88_RS10615	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BXT88_RS10625	COG0583	DNA-binding transcription factor activity
BXT88_RS10635	COG1053	succinate dehydrogenase
BXT88_RS10640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BXT88_RS10645	COG0107	imidazoleglycerol-phosphate synthase activity
BXT88_RS10650	COG0251	oxidation-reduction process
BXT88_RS10655	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BXT88_RS10660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BXT88_RS10665	COG0131	Imidazoleglycerol-phosphate dehydratase
BXT88_RS10670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXT88_RS10675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BXT88_RS10690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BXT88_RS10710	COG1432	Conserved Protein
BXT88_RS10715	COG0587	DNA-directed DNA polymerase activity
BXT88_RS10770	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BXT88_RS10780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BXT88_RS10795	COG1799	cell septum assembly
BXT88_RS10805	COG1496	oxidoreductase activity
BXT88_RS10810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BXT88_RS10815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BXT88_RS10820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BXT88_RS10830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BXT88_RS10835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXT88_RS10840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BXT88_RS10845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BXT88_RS10860	COG0275	rRNA processing
BXT88_RS10870	COG0714	Associated with various cellular activities
BXT88_RS10890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXT88_RS10900	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BXT88_RS10910	COG1309	transcriptional regulator
BXT88_RS10920	COG1233	COG1233 Phytoene dehydrogenase and related
BXT88_RS10935	COG0352	thiamine-phosphate diphosphorylase activity
BXT88_RS10950	COG2022	thiamine diphosphate biosynthetic process
BXT88_RS10950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXT88_RS10960	COG2022	thiamine diphosphate biosynthetic process
BXT88_RS10965	COG0515	serine threonine protein kinase
BXT88_RS10965	COG2815	serine threonine protein kinase
BXT88_RS10970	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BXT88_RS10975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BXT88_RS10980	COG2193	ferroxidase activity
BXT88_RS10990	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BXT88_RS11000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BXT88_RS11005	COG0205	6-phosphofructokinase activity
BXT88_RS11010	COG2197	response regulator
BXT88_RS11040	COG1940	carbohydrate kinase activity
BXT88_RS11050	COG0003	Pfam Anion-transporting ATPase
BXT88_RS11070	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS11115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXT88_RS11120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BXT88_RS11125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BXT88_RS11130	COG0723	plastoquinol--plastocyanin reductase activity
BXT88_RS11135	COG2010	Cytochrome c
BXT88_RS11140	COG1845	cytochrome c oxidase, subunit III
BXT88_RS11150	COG1376	ErfK ybiS ycfS ynhG family protein
BXT88_RS11160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BXT88_RS11165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BXT88_RS11175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXT88_RS11195	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BXT88_RS11220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXT88_RS11225	COG2197	response regulator
BXT88_RS11230	COG4585	Histidine kinase
BXT88_RS11265	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BXT88_RS11270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BXT88_RS11270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BXT88_RS11285	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BXT88_RS11290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXT88_RS11295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXT88_RS11300	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXT88_RS11310	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BXT88_RS11320	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS11350	COG0321	lipoyl(octanoyl) transferase activity
BXT88_RS11355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BXT88_RS11405	COG1414	Transcriptional regulator
BXT88_RS11410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BXT88_RS11420	COG0583	DNA-binding transcription factor activity
BXT88_RS11440	COG1902	pentaerythritol trinitrate reductase activity
BXT88_RS11440	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXT88_RS11455	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS11485	COG0745	RESPONSE REGULATOR receiver
BXT88_RS11600	COG0366	Alpha amylase catalytic
BXT88_RS11605	COG0395	ABC-type sugar transport system, permease component
BXT88_RS11610	COG1175	transmembrane transport
BXT88_RS11615	COG2182	Extracellular solute-binding protein
BXT88_RS11620	COG0366	Alpha amylase catalytic
BXT88_RS11625	COG1609	Transcriptional regulator
BXT88_RS11635	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BXT88_RS11640	COG0174	glutamine synthetase
BXT88_RS11660	COG2267	carboxylic ester hydrolase activity
BXT88_RS11675	COG2132	Multicopper oxidase
BXT88_RS11680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXT88_RS11680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BXT88_RS11685	COG2814	Major facilitator Superfamily
BXT88_RS11695	COG1309	transcriptional regulator
BXT88_RS11700	COG0477	Major facilitator Superfamily
BXT88_RS11705	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BXT88_RS11725	COG1994	Peptidase M50
BXT88_RS11745	COG0395	ABC-type sugar transport system, permease component
BXT88_RS11750	COG1175	transmembrane transport
BXT88_RS11765	COG2186	Transcriptional regulator
BXT88_RS11770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXT88_RS11795	COG5398	heme oxygenase
BXT88_RS11810	COG2837	iron assimilation
BXT88_RS11815	COG0672	)-iron permease
BXT88_RS11830	COG1309	transcriptional regulator
BXT88_RS11835	COG1834	amidinotransferase
BXT88_RS11845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BXT88_RS11850	COG2814	Major facilitator Superfamily
BXT88_RS11855	COG3540	Alkaline phosphatase
BXT88_RS11890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BXT88_RS11950	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BXT88_RS11955	COG3022	response to hydroperoxide
BXT88_RS11960	COG0800	Aldolase
BXT88_RS11975	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BXT88_RS11985	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS11995	COG2030	dehydratase
BXT88_RS12000	COG1131	(ABC) transporter
BXT88_RS12010	COG4585	Histidine kinase
BXT88_RS12015	COG2197	response regulator
BXT88_RS12035	COG0183	Belongs to the thiolase family
BXT88_RS12040	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS12045	COG3510	cephalosporin hydroxylase
BXT88_RS12050	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXT88_RS12060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS12080	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS12085	COG1309	transcriptional regulator
BXT88_RS12120	COG3845	ABC transporter
BXT88_RS12135	COG0183	Belongs to the thiolase family
BXT88_RS12140	COG2124	cytochrome p450
BXT88_RS12165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BXT88_RS12180	COG0477	Major facilitator Superfamily
BXT88_RS12265	COG1309	transcriptional regulator
BXT88_RS12270	COG0662	Cupin 2, conserved barrel domain protein
BXT88_RS12275	COG1072	(Pantothenic acid kinase))
BXT88_RS12290	COG0596	Alpha beta hydrolase
BXT88_RS12295	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BXT88_RS12350	COG4974	Belongs to the 'phage' integrase family
BXT88_RS12380	COG0800	Aldolase
BXT88_RS12405	COG1358	cellular component organization or biogenesis
BXT88_RS12450	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BXT88_RS12460	COG0477	Major facilitator Superfamily
BXT88_RS12465	COG1309	transcriptional regulator
BXT88_RS12480	COG4585	Histidine kinase
BXT88_RS12485	COG2197	response regulator
BXT88_RS12500	COG0667	Aldo Keto reductase
BXT88_RS12505	COG0789	Transcriptional regulator
BXT88_RS12525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BXT88_RS12530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXT88_RS12535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXT88_RS12540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXT88_RS12575	COG1309	transcriptional regulator
BXT88_RS12595	COG2423	ornithine cyclodeaminase activity
BXT88_RS12600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXT88_RS12605	COG1879	ABC-type sugar transport system periplasmic component
BXT88_RS12610	COG1172	Belongs to the binding-protein-dependent transport system permease family
BXT88_RS12615	COG1129	ABC transporter
BXT88_RS12620	COG1609	Transcriptional regulator
BXT88_RS12630	COG1764	response to oxidative stress
BXT88_RS12635	COG2130	NADP-dependent
BXT88_RS12645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BXT88_RS12650	COG0477	Major facilitator Superfamily
BXT88_RS12665	COG1077	Cell shape determining protein MreB Mrl
BXT88_RS12670	COG0588	phosphoglycerate mutase activity
BXT88_RS12675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXT88_RS12715	COG1070	Carbohydrate kinase
BXT88_RS12720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXT88_RS12725	COG0358	DNA primase activity
BXT88_RS12740	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BXT88_RS12750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BXT88_RS12785	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BXT88_RS12800	COG0667	Aldo Keto reductase
BXT88_RS12825	COG1473	amidohydrolase
BXT88_RS12830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXT88_RS12850	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS12870	COG2197	response regulator
BXT88_RS12880	COG2146	nitrite reductase [NAD(P)H] activity
BXT88_RS12880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXT88_RS12895	COG0640	Transcriptional regulator
BXT88_RS12905	COG0531	amino acid
BXT88_RS12975	COG2182	Extracellular solute-binding protein
BXT88_RS12980	COG1175	transmembrane transport
BXT88_RS12985	COG0395	ABC-type sugar transport system, permease component
BXT88_RS12990	COG2175	clavaminate synthase activity
BXT88_RS13000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXT88_RS13000	COG0574	Belongs to the PEP-utilizing enzyme family
BXT88_RS13025	COG0477	Major facilitator Superfamily
BXT88_RS13030	COG0667	Aldo Keto reductase
BXT88_RS13065	COG2197	response regulator
BXT88_RS13085	COG0423	glycine-tRNA ligase activity
BXT88_RS13090	COG3443	Belongs to the bacterial solute-binding protein 9 family
BXT88_RS13090	COG0803	Belongs to the bacterial solute-binding protein 9 family
BXT88_RS13095	COG1121	(ABC) transporter
BXT88_RS13100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BXT88_RS13110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BXT88_RS13115	COG1381	Involved in DNA repair and RecF pathway recombination
BXT88_RS13150	COG2124	cytochrome p450
BXT88_RS13165	COG2755	lipolytic protein G-D-S-L family
BXT88_RS13170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXT88_RS13185	COG2723	6-phospho-beta-galactosidase activity
BXT88_RS13195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BXT88_RS13210	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BXT88_RS13220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXT88_RS13225	COG1486	melibiose metabolic process
BXT88_RS13240	COG4948	Mandelate Racemase Muconate Lactonizing
BXT88_RS13250	COG1234	tRNA 3'-trailer cleavage
BXT88_RS13255	COG0537	adenosine 5'-monophosphoramidase activity
BXT88_RS13275	COG0484	heat shock protein binding
BXT88_RS13280	COG1420	regulation of RNA biosynthetic process
BXT88_RS13315	COG0481	GTPase activity
BXT88_RS13320	COG0268	Binds directly to 16S ribosomal RNA
BXT88_RS13345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BXT88_RS13350	COG1234	tRNA 3'-trailer cleavage
BXT88_RS13355	COG1555	photosystem II stabilization
BXT88_RS13360	COG1307	EDD domain protein, DegV family
BXT88_RS13370	COG0495	leucyl-tRNA aminoacylation
BXT88_RS13385	COG1051	belongs to the nudix hydrolase family
BXT88_RS13405	COG0588	phosphoglycerate mutase activity
BXT88_RS13410	COG0799	negative regulation of ribosome biogenesis
BXT88_RS13420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BXT88_RS13425	COG0501	Belongs to the peptidase M48B family
BXT88_RS13440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BXT88_RS13450	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BXT88_RS13460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BXT88_RS13465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BXT88_RS13470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BXT88_RS13475	COG1530	ribonuclease E activity
BXT88_RS13510	COG0772	Belongs to the SEDS family
BXT88_RS13515	COG0768	penicillin binding
BXT88_RS13530	COG1077	Cell shape determining protein MreB Mrl
BXT88_RS13535	COG0105	UTP biosynthetic process
BXT88_RS13545	COG0285	dihydrofolate synthase activity
BXT88_RS13550	COG0768	penicillin binding
BXT88_RS13560	COG0525	valine-tRNA ligase activity
BXT88_RS13570	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BXT88_RS13575	COG0740	serine-type endopeptidase activity
BXT88_RS13580	COG0740	serine-type endopeptidase activity
BXT88_RS13585	COG0544	peptidyl-prolyl cis-trans isomerase activity
BXT88_RS13610	COG3594	Acyltransferase
BXT88_RS13620	COG4552	Acetyltransferase involved in intracellular survival and related
BXT88_RS13630	COG0698	ribose 5-phosphate isomerase
BXT88_RS13635	COG1113	amino acid transport
BXT88_RS13645	COG1113	amino acid transport
BXT88_RS13650	COG1113	amino acid transport
BXT88_RS13655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXT88_RS13660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BXT88_RS13695	COG4266	Belongs to the allantoicase family
BXT88_RS13745	COG0668	transmembrane transport
BXT88_RS13750	COG1940	carbohydrate kinase activity
BXT88_RS13750	COG1846	Transcriptional regulator
BXT88_RS13755	COG1653	transport
BXT88_RS13760	COG1175	transmembrane transport
BXT88_RS13765	COG0395	ABC-type sugar transport system, permease component
BXT88_RS13770	COG1486	melibiose metabolic process
BXT88_RS13785	COG2186	Transcriptional regulator
BXT88_RS13795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXT88_RS13820	COG2346	COG2346, Truncated hemoglobins
BXT88_RS13835	COG0577	efflux transmembrane transporter activity
BXT88_RS13835	COG1136	(ABC) transporter
BXT88_RS13860	COG0629	single-stranded DNA binding
BXT88_RS13865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BXT88_RS13915	COG1674	ftsk spoiiie
BXT88_RS13955	COG1051	belongs to the nudix hydrolase family
BXT88_RS13965	COG2186	Transcriptional regulator
BXT88_RS13985	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BXT88_RS13995	COG0596	Alpha beta hydrolase
BXT88_RS14010	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BXT88_RS14025	COG1131	(ABC) transporter
BXT88_RS14030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXT88_RS14045	COG3962	Belongs to the TPP enzyme family
BXT88_RS14050	COG3718	enzyme involved in inositol metabolism
BXT88_RS14060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXT88_RS14075	COG0673	inositol 2-dehydrogenase activity
BXT88_RS14080	COG2814	Major facilitator Superfamily
BXT88_RS14095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BXT88_RS14100	COG1609	Transcriptional regulator
BXT88_RS14105	COG0673	inositol 2-dehydrogenase activity
BXT88_RS14110	COG0586	Pfam SNARE associated Golgi protein
BXT88_RS14115	COG2608	mercury ion transmembrane transporter activity
BXT88_RS14125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BXT88_RS14140	COG0673	inositol 2-dehydrogenase activity
BXT88_RS14145	COG1609	Transcriptional regulator
BXT88_RS14160	COG1472	Belongs to the glycosyl hydrolase 3 family
BXT88_RS14175	COG1554	hydrolase, family 65, central catalytic
BXT88_RS14180	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BXT88_RS14190	COG1309	transcriptional regulator
BXT88_RS14195	COG0028	Belongs to the TPP enzyme family
BXT88_RS14235	COG1946	Acyl-CoA thioesterase
BXT88_RS14245	COG1309	transcriptional regulator
BXT88_RS14250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXT88_RS14265	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS14280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXT88_RS14285	COG0589	response to stress
BXT88_RS14295	COG4977	sequence-specific DNA binding
BXT88_RS14300	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BXT88_RS14320	COG3979	chitinase
BXT88_RS14355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BXT88_RS14370	COG0492	ferredoxin-NADP+ reductase activity
BXT88_RS14430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS14450	COG0154	amidase activity
BXT88_RS14470	COG0765	amino acid transport
BXT88_RS14475	COG0765	amino acid transport
BXT88_RS14480	COG1126	abc transporter atp-binding protein
BXT88_RS14510	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS14610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXT88_RS14615	COG2188	Transcriptional regulator
BXT88_RS14625	COG0673	inositol 2-dehydrogenase activity
BXT88_RS14630	COG4702	Belongs to the UPF0303 family
BXT88_RS14635	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXT88_RS14710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXT88_RS14755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXT88_RS14765	COG3764	Sortase (surface protein transpeptidase)
BXT88_RS14800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXT88_RS14805	COG2076	Multidrug Resistance protein
BXT88_RS14810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BXT88_RS14825	COG2205	protein histidine kinase activity
BXT88_RS14855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BXT88_RS14865	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BXT88_RS14870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BXT88_RS14875	COG1263	PTS System
BXT88_RS14880	COG1263	PTS System
BXT88_RS14885	COG1234	tRNA 3'-trailer cleavage
BXT88_RS14910	COG1113	amino acid transport
BXT88_RS14920	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BXT88_RS14930	COG1335	isochorismatase
BXT88_RS14970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXT88_RS14975	COG0222	ribosome binding
BXT88_RS14985	COG0277	FAD linked oxidase domain protein
BXT88_RS14990	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BXT88_RS15000	COG1174	glycine betaine transport
BXT88_RS15010	COG1174	glycine betaine transport
BXT88_RS15035	COG0477	Major facilitator Superfamily
BXT88_RS15055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BXT88_RS15070	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BXT88_RS15080	COG2814	Major facilitator Superfamily
BXT88_RS15085	COG0583	DNA-binding transcription factor activity
BXT88_RS15095	COG1678	Uncharacterized ACR, COG1678
BXT88_RS15100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BXT88_RS15105	COG0776	regulation of translation
BXT88_RS15115	COG3973	AAA domain
BXT88_RS15145	COG2223	nitrite transmembrane transporter activity
BXT88_RS15160	COG0583	DNA-binding transcription factor activity
BXT88_RS15175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BXT88_RS15180	COG0793	Belongs to the peptidase S41A family
BXT88_RS15185	COG2177	Part of the ABC transporter FtsEX involved in
BXT88_RS15190	COG2884	Cell division ATP-binding protein ftsE
BXT88_RS15205	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BXT88_RS15210	COG0515	serine threonine protein kinase
BXT88_RS15215	COG0515	serine threonine protein kinase
BXT88_RS15225	COG1653	transport
BXT88_RS15230	COG1175	transmembrane transport
BXT88_RS15235	COG0395	ABC-type sugar transport system, permease component
BXT88_RS15250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BXT88_RS15255	COG1215	transferase activity, transferring glycosyl groups
BXT88_RS15280	COG0463	Glycosyl transferase, family 2
BXT88_RS15295	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BXT88_RS15295	COG0463	Glycosyl transferase, family 2
BXT88_RS15300	COG1309	transcriptional regulator
BXT88_RS15310	COG1134	teichoic acid transport
BXT88_RS15315	COG2902	Dehydrogenase
BXT88_RS15335	COG0653	protein targeting
BXT88_RS15350	COG2197	response regulator
BXT88_RS15355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BXT88_RS15365	COG0823	Involved in the tonB-independent uptake of proteins
BXT88_RS15370	COG5002	protein histidine kinase activity
BXT88_RS15370	COG5000	phosphorelay sensor kinase activity
BXT88_RS15375	COG0745	RESPONSE REGULATOR receiver
BXT88_RS15380	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BXT88_RS15400	COG0714	Associated with various cellular activities
BXT88_RS15445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BXT88_RS15450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXT88_RS15450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXT88_RS15450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXT88_RS15460	COG1482	cell wall glycoprotein biosynthetic process
BXT88_RS15470	COG2835	tetraacyldisaccharide 4'-kinase activity
BXT88_RS15475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXT88_RS15510	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BXT88_RS15515	COG0778	Nitroreductase
BXT88_RS15515	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BXT88_RS15545	COG1316	TRANSCRIPTIONal
BXT88_RS15560	COG1316	TRANSCRIPTIONal
BXT88_RS15580	COG1316	TRANSCRIPTIONal
BXT88_RS15595	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BXT88_RS15635	COG2205	protein histidine kinase activity
BXT88_RS15640	COG0745	RESPONSE REGULATOR receiver
BXT88_RS15645	COG3104	oligopeptide transport
BXT88_RS15675	COG1366	Belongs to the anti-sigma-factor antagonist family
BXT88_RS15680	COG1191	sigma factor activity
BXT88_RS15685	COG1228	amidohydrolase
BXT88_RS15700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BXT88_RS15720	COG0842	Transport permease protein
BXT88_RS15725	COG0019	diaminopimelate decarboxylase activity
BXT88_RS15735	COG2986	histidine ammonia-lyase
BXT88_RS15745	COG1174	glycine betaine transport
BXT88_RS15750	COG1174	glycine betaine transport
BXT88_RS15765	COG2226	methyltransferase
BXT88_RS15770	COG1609	Transcriptional regulator
BXT88_RS15785	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BXT88_RS15800	COG2755	lipolytic protein G-D-S-L family
BXT88_RS15805	COG0183	Belongs to the thiolase family
BXT88_RS15830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BXT88_RS15845	COG1136	(ABC) transporter
BXT88_RS15845	COG0577	efflux transmembrane transporter activity
BXT88_RS15850	COG0577	efflux transmembrane transporter activity
BXT88_RS15855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BXT88_RS15880	COG0148	phosphopyruvate hydratase activity
BXT88_RS15895	COG2124	cytochrome p450
BXT88_RS15905	COG2814	Major facilitator Superfamily
BXT88_RS15925	COG2318	DinB family
BXT88_RS15930	COG2815	serine threonine protein kinase
BXT88_RS15930	COG0515	serine threonine protein kinase
BXT88_RS15960	COG2814	Major facilitator Superfamily
BXT88_RS15970	COG1316	TRANSCRIPTIONal
BXT88_RS15995	COG4585	Histidine kinase
BXT88_RS16005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BXT88_RS16010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BXT88_RS16015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BXT88_RS16020	COG0193	aminoacyl-tRNA hydrolase activity
BXT88_RS16030	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BXT88_RS16040	COG1309	transcriptional regulator
BXT88_RS16070	COG4106	trans-aconitate 2-methyltransferase activity
BXT88_RS16080	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS16090	COG2197	response regulator
BXT88_RS16095	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BXT88_RS16130	COG0488	(ABC) transporter
BXT88_RS16145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BXT88_RS16170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BXT88_RS16175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BXT88_RS16185	COG0084	hydrolase, TatD family'
BXT88_RS16225	COG1122	ATPase activity
BXT88_RS16235	COG0310	cobalt ion transport
BXT88_RS16245	COG4946	Tricorn protease homolog
BXT88_RS16245	COG0793	Belongs to the peptidase S41A family
BXT88_RS16265	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS16270	COG2267	carboxylic ester hydrolase activity
BXT88_RS16275	COG2072	flavoprotein involved in K transport
BXT88_RS16285	COG3629	intracellular signal transduction
BXT88_RS16285	COG3903	Transcriptional regulator
BXT88_RS16295	COG0708	Exodeoxyribonuclease III
BXT88_RS16305	COG1131	(ABC) transporter
BXT88_RS16315	COG1725	Transcriptional regulator
BXT88_RS16320	COG0789	Transcriptional regulator
BXT88_RS16350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXT88_RS16355	COG0521	Mo-molybdopterin cofactor biosynthetic process
BXT88_RS16355	COG0315	cyclic pyranopterin monophosphate synthase activity
BXT88_RS16360	COG0315	cyclic pyranopterin monophosphate synthase activity
BXT88_RS16370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BXT88_RS16375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BXT88_RS16385	COG3263	regulation of cellular component size
BXT88_RS16400	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BXT88_RS16405	COG1970	mechanosensitive ion channel activity
BXT88_RS16420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXT88_RS16425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BXT88_RS16430	COG2188	Transcriptional regulator
BXT88_RS16470	COG3191	aminopeptidase activity
BXT88_RS16490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BXT88_RS16505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BXT88_RS16520	COG1105	Belongs to the carbohydrate kinase PfkB family
BXT88_RS16525	COG1349	DNA-binding transcription factor activity
BXT88_RS16535	COG1247	-acetyltransferase
BXT88_RS16550	COG3384	dioxygenase
BXT88_RS16555	COG1846	Transcriptional regulator
BXT88_RS16575	COG1309	transcriptional regulator
BXT88_RS16625	COG0513	Belongs to the DEAD box helicase family
BXT88_RS16630	COG1278	Cold shock
BXT88_RS16635	COG1846	Transcriptional regulator
BXT88_RS16640	COG1902	pentaerythritol trinitrate reductase activity
BXT88_RS16665	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS16665	COG0604	alcohol dehydrogenase
BXT88_RS16665	COG3321	synthase
BXT88_RS16670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXT88_RS16690	COG0514	ATP-dependent DNA helicase (RecQ)
BXT88_RS16710	COG1686	Belongs to the peptidase S11 family
BXT88_RS16735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXT88_RS16740	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS16755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BXT88_RS16770	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BXT88_RS16870	COG1024	Enoyl-CoA hydratase
BXT88_RS16885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXT88_RS16885	COG0515	serine threonine protein kinase
BXT88_RS16900	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS16930	COG0259	pyridoxamine-phosphate oxidase activity
BXT88_RS16950	COG1024	Enoyl-CoA hydratase
BXT88_RS16980	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS16985	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS17000	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS17005	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS17050	COG0516	GMP reductase activity
BXT88_RS17060	COG1595	DNA-templated transcription, initiation
BXT88_RS17075	COG0583	DNA-binding transcription factor activity
BXT88_RS17085	COG4221	oxidoreductase activity
BXT88_RS17105	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BXT88_RS17110	COG0772	Belongs to the SEDS family
BXT88_RS17125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BXT88_RS17150	COG0802	atpase or kinase
BXT88_RS17160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BXT88_RS17165	COG1376	ErfK ybiS ycfS ynhG family protein
BXT88_RS17175	COG0736	holo-[acyl-carrier-protein] synthase activity
BXT88_RS17180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXT88_RS17190	COG1072	(Pantothenic acid kinase))
BXT88_RS17200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXT88_RS17205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BXT88_RS17210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BXT88_RS17215	COG0488	(ABC) transporter
BXT88_RS17225	COG0101	tRNA pseudouridine synthase activity
BXT88_RS17230	COG0203	ribosomal protein L17
BXT88_RS17235	COG0202	RNA polymerase activity
BXT88_RS17240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BXT88_RS17245	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BXT88_RS17250	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BXT88_RS17255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BXT88_RS17260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BXT88_RS17270	COG0563	adenylate kinase activity
BXT88_RS17280	COG0200	Binds to the 23S rRNA
BXT88_RS17285	COG1841	ribosomal large subunit assembly
BXT88_RS17290	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BXT88_RS17295	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BXT88_RS17300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BXT88_RS17305	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BXT88_RS17315	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BXT88_RS17320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BXT88_RS17325	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BXT88_RS17330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BXT88_RS17335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BXT88_RS17340	COG0255	Belongs to the universal ribosomal protein uL29 family
BXT88_RS17345	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BXT88_RS17350	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BXT88_RS17355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BXT88_RS17360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BXT88_RS17365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BXT88_RS17370	COG0089	rRNA binding
BXT88_RS17375	COG0088	Forms part of the polypeptide exit tunnel
BXT88_RS17380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BXT88_RS17385	COG0051	transcription antitermination factor activity, RNA binding
BXT88_RS17390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BXT88_RS17395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BXT88_RS17400	COG0049	tRNA binding
BXT88_RS17405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BXT88_RS17415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BXT88_RS17420	COG0085	RNA polymerase activity
BXT88_RS17430	COG0222	ribosome binding
BXT88_RS17435	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BXT88_RS17445	COG0081	regulation of translation
BXT88_RS17450	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BXT88_RS17455	COG0250	Participates in transcription elongation, termination and antitermination
BXT88_RS17470	COG0436	Aminotransferase
BXT88_RS17475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BXT88_RS17480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BXT88_RS17490	COG2030	dehydratase
BXT88_RS17495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BXT88_RS17510	COG0402	S-adenosylhomocysteine deaminase activity
BXT88_RS17515	COG0702	epimerase
BXT88_RS17525	COG1666	GTP binding
BXT88_RS17535	COG3304	Inner membrane component domain
BXT88_RS17540	COG0501	Belongs to the peptidase M48B family
BXT88_RS17545	COG1007	ATP synthesis coupled electron transport
BXT88_RS17555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXT88_RS17560	COG0713	ATP synthesis coupled electron transport
BXT88_RS17570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXT88_RS17575	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BXT88_RS17580	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXT88_RS17585	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXT88_RS17590	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXT88_RS17605	COG4585	Histidine kinase
BXT88_RS17610	COG4585	Histidine kinase
BXT88_RS17620	COG0674	pyruvate-flavodoxin oxidoreductase activity
BXT88_RS17620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BXT88_RS17625	COG1013	pyruvate-flavodoxin oxidoreductase activity
BXT88_RS17630	COG0702	epimerase
BXT88_RS17645	COG1131	(ABC) transporter
BXT88_RS17655	COG0142	geranyltranstransferase activity
BXT88_RS17685	COG1007	ATP synthesis coupled electron transport
BXT88_RS17695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXT88_RS17700	COG0713	ATP synthesis coupled electron transport
BXT88_RS17705	COG0839	Belongs to the complex I subunit 6 family
BXT88_RS17710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXT88_RS17715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BXT88_RS17720	COG1034	ATP synthesis coupled electron transport
BXT88_RS17725	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BXT88_RS17735	COG0649	NAD binding
BXT88_RS17740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXT88_RS17745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXT88_RS17755	COG3103	Sh3 type 3 domain protein
BXT88_RS17755	COG1388	LysM domain
BXT88_RS17755	COG0791	NLP P60 protein
BXT88_RS17785	COG2226	methyltransferase
BXT88_RS17795	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BXT88_RS17805	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BXT88_RS17810	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BXT88_RS17815	COG1278	Cold shock
BXT88_RS17860	COG1309	transcriptional regulator
BXT88_RS17870	COG1301	dicarboxylic acid transport
BXT88_RS17885	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BXT88_RS17895	COG0163	prenyltransferase activity
BXT88_RS17905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BXT88_RS17910	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BXT88_RS17945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXT88_RS17950	COG1333	cytochrome c biogenesis protein
BXT88_RS17970	COG0406	alpha-ribazole phosphatase activity
BXT88_RS17975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BXT88_RS17985	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS18010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXT88_RS18020	COG1742	UPF0060 membrane protein
BXT88_RS18030	COG1690	Belongs to the RtcB family
BXT88_RS18050	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BXT88_RS18055	COG0018	arginyl-trna synthetase
BXT88_RS18065	COG0113	porphobilinogen synthase activity
BXT88_RS18070	COG1648	precorrin-2 dehydrogenase activity
BXT88_RS18070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXT88_RS18075	COG0181	hydroxymethylbilane synthase activity
BXT88_RS18080	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BXT88_RS18085	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BXT88_RS18135	COG0123	including yeast histone deacetylase and acetoin utilization protein
BXT88_RS18140	COG2223	nitrite transmembrane transporter activity
BXT88_RS18165	COG1846	Transcriptional regulator
BXT88_RS18180	COG1252	NADH dehydrogenase
BXT88_RS18205	COG0579	oxidoreductase
BXT88_RS18215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BXT88_RS18235	COG0667	Aldo Keto reductase
BXT88_RS18260	COG0513	Belongs to the DEAD box helicase family
BXT88_RS18300	COG1643	Atp-dependent helicase
BXT88_RS18335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BXT88_RS18350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BXT88_RS18355	COG0047	phosphoribosylformylglycinamidine synthase activity
BXT88_RS18360	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BXT88_RS18380	COG1131	(ABC) transporter
BXT88_RS18395	COG2197	response regulator
BXT88_RS18405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BXT88_RS18420	COG0151	Belongs to the GarS family
BXT88_RS18435	COG1802	Transcriptional regulator
BXT88_RS18440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BXT88_RS18450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXT88_RS18450	COG0515	serine threonine protein kinase
BXT88_RS18460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BXT88_RS18480	COG1131	(ABC) transporter
BXT88_RS18485	COG3559	Exporter of polyketide antibiotics
BXT88_RS18490	COG2197	response regulator
BXT88_RS18495	COG4585	Histidine kinase
BXT88_RS18505	COG3844	kynureninase activity
BXT88_RS18510	COG3483	tryptophan 2,3-dioxygenase activity
BXT88_RS18520	COG0477	Major facilitator Superfamily
BXT88_RS18525	COG0191	fructose-bisphosphate aldolase activity
BXT88_RS18530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BXT88_RS18545	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BXT88_RS18570	COG0542	response to heat
BXT88_RS18595	COG0789	Transcriptional regulator
BXT88_RS18600	COG0484	heat shock protein binding
BXT88_RS18605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BXT88_RS18610	COG0443	Heat shock 70 kDa protein
BXT88_RS18615	COG2181	nitrate reductase activity
BXT88_RS18615	COG0247	lactate metabolic process
BXT88_RS18655	COG0717	Belongs to the dCTP deaminase family
BXT88_RS18665	COG1846	Transcriptional regulator
BXT88_RS18670	COG0778	Nitroreductase
BXT88_RS18685	COG0346	lactoylglutathione lyase activity
BXT88_RS18715	COG1674	ftsk spoiiie
BXT88_RS18795	COG2205	protein histidine kinase activity
BXT88_RS18800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BXT88_RS18805	COG0515	serine threonine protein kinase
BXT88_RS18845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BXT88_RS18850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXT88_RS18860	COG1652	LysM domain
BXT88_RS18875	COG2197	response regulator
BXT88_RS18885	COG0515	serine threonine protein kinase
BXT88_RS18895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXT88_RS18920	COG0028	Belongs to the TPP enzyme family
BXT88_RS18940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXT88_RS18950	COG2030	dehydratase
BXT88_RS18955	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS18995	COG1316	TRANSCRIPTIONal
BXT88_RS19065	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BXT88_RS19110	COG0745	RESPONSE REGULATOR receiver
BXT88_RS19115	COG0517	IMP dehydrogenase activity
BXT88_RS19115	COG1125	glycine betaine transport
BXT88_RS19125	COG1174	glycine betaine transport
BXT88_RS19130	COG1174	glycine betaine transport
BXT88_RS19160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXT88_RS19170	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BXT88_RS19195	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS19200	COG1362	aminopeptidase activity
BXT88_RS19205	COG3629	intracellular signal transduction
BXT88_RS19205	COG3903	Transcriptional regulator
BXT88_RS19255	COG0494	nUDIX hydrolase
BXT88_RS19260	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXT88_RS19265	COG0022	dehydrogenase e1 component
BXT88_RS19290	COG0515	serine threonine protein kinase
BXT88_RS19295	COG0515	serine threonine protein kinase
BXT88_RS19315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BXT88_RS19345	COG1522	sequence-specific DNA binding
BXT88_RS19350	COG1309	transcriptional regulator
BXT88_RS19355	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXT88_RS19380	COG3396	Phenylacetate-CoA oxygenase
BXT88_RS19385	COG3460	Phenylacetate-CoA oxygenase
BXT88_RS19390	COG3396	Phenylacetate-CoA oxygenase
BXT88_RS19395	COG2151	metal-sulfur cluster biosynthetic enzyme
BXT88_RS19400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BXT88_RS19435	COG1733	regulation of RNA biosynthetic process
BXT88_RS19440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BXT88_RS19445	COG2814	Major facilitator Superfamily
BXT88_RS19450	COG0583	DNA-binding transcription factor activity
BXT88_RS19460	COG1716	ATPase activity
BXT88_RS19465	COG1716	ATPase activity
BXT88_RS19475	COG0772	Belongs to the SEDS family
BXT88_RS19490	COG0515	serine threonine protein kinase
BXT88_RS19495	COG3764	Sortase (surface protein transpeptidase)
BXT88_RS19500	COG3764	Sortase (surface protein transpeptidase)
BXT88_RS19510	COG3764	Sortase (surface protein transpeptidase)
BXT88_RS19525	COG0705	Rhomboid family
BXT88_RS19565	COG0515	serine threonine protein kinase
BXT88_RS19595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BXT88_RS19600	COG0187	DNA topoisomerase II activity
BXT88_RS19605	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
BXT88_RS19610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXT88_RS19615	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BXT88_RS19620	COG0592	DNA-directed DNA polymerase activity
BXT88_RS19635	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BXT88_RS19645	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BXT88_RS19650	COG0706	membrane insertase activity
BXT88_RS19655	COG1847	R3H domain protein
BXT88_RS19660	COG0357	Ribosomal RNA small subunit methyltransferase G
BXT88_RS19665	COG1192	Involved in chromosome partitioning
BXT88_RS19680	COG3118	belongs to the thioredoxin family
BXT88_RS19685	COG0492	ferredoxin-NADP+ reductase activity
BXT88_RS19695	COG1595	DNA-templated transcription, initiation
BXT88_RS19700	COG0515	serine threonine protein kinase
BXT88_RS19700	COG2815	serine threonine protein kinase
BXT88_RS19705	COG0728	peptidoglycan biosynthetic process
BXT88_RS19715	COG0617	tRNA 3'-terminal CCA addition
BXT88_RS19740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BXT88_RS19765	COG0360	Binds together with S18 to 16S ribosomal RNA
BXT88_RS19770	COG0629	single-stranded DNA binding
BXT88_RS19775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BXT88_RS19780	COG0359	binds to the 23S rRNA
BXT88_RS19790	COG0534	Mate efflux family protein
BXT88_RS19795	COG0305	Participates in initiation and elongation during chromosome replication
BXT88_RS19805	COG0789	Transcriptional regulator
BXT88_RS19810	COG4978	Transcriptional regulator
BXT88_RS19810	COG0789	Transcriptional regulator
BXT88_RS19840	COG1846	Transcriptional regulator
BXT88_RS19845	COG2814	Major facilitator Superfamily
BXT88_RS19875	COG0494	nUDIX hydrolase
BXT88_RS19885	COG0626	cystathionine gamma-synthase activity
BXT88_RS19890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXT88_RS19895	COG1950	PFAM Membrane protein of
BXT88_RS19900	COG0662	Cupin 2, conserved barrel domain protein
BXT88_RS19925	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BXT88_RS19935	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BXT88_RS19940	COG1609	Transcriptional regulator
BXT88_RS19945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXT88_RS19955	COG1271	oxidase subunit
BXT88_RS19960	COG1294	oxidase, subunit
BXT88_RS19965	COG4988	ABC transporter
BXT88_RS19975	COG0561	phosphatase activity
BXT88_RS19985	COG0501	Belongs to the peptidase M48B family
BXT88_RS19995	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BXT88_RS20010	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BXT88_RS20015	COG0789	Transcriptional regulator
BXT88_RS20035	COG1131	(ABC) transporter
BXT88_RS20060	COG2807	transmembrane transport
BXT88_RS20065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXT88_RS20080	COG0789	Transcriptional regulator
BXT88_RS20100	COG0561	phosphatase activity
BXT88_RS20105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BXT88_RS20110	COG0077	Prephenate dehydratase
BXT88_RS20115	COG2837	iron assimilation
BXT88_RS20120	COG2372	response to copper ion
BXT88_RS20155	COG0667	Aldo Keto reductase
BXT88_RS20165	COG1132	(ABC) transporter
BXT88_RS20175	COG0006	proline dipeptidase activity
BXT88_RS20210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXT88_RS20230	COG0305	Participates in initiation and elongation during chromosome replication
BXT88_RS20275	COG2188	Transcriptional regulator
BXT88_RS20280	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BXT88_RS20315	COG3409	Peptidoglycan-binding domain 1 protein
BXT88_RS20315	COG5632	N-Acetylmuramoyl-L-alanine amidase
BXT88_RS20355	COG1595	DNA-templated transcription, initiation
BXT88_RS20405	COG3437	response regulator, receiver
BXT88_RS20410	COG2205	protein histidine kinase activity
BXT88_RS20410	COG3437	response regulator, receiver
BXT88_RS20410	COG3850	Histidine kinase
BXT88_RS20410	COG4999	Histidine kinase
BXT88_RS20425	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS20430	COG0784	Response regulator, receiver
BXT88_RS20505	COG2188	Transcriptional regulator
BXT88_RS20545	COG2249	NAD(P)H dehydrogenase (quinone) activity
BXT88_RS20570	COG0745	RESPONSE REGULATOR receiver
BXT88_RS20580	COG2205	protein histidine kinase activity
BXT88_RS20590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BXT88_RS20595	COG0477	Major facilitator Superfamily
BXT88_RS20610	COG0477	Major facilitator Superfamily
BXT88_RS20640	COG2226	methyltransferase
BXT88_RS20655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BXT88_RS20700	COG4221	oxidoreductase activity
BXT88_RS20715	COG1191	sigma factor activity
BXT88_RS20720	COG1191	sigma factor activity
BXT88_RS20745	COG0590	tRNA wobble adenosine to inosine editing
BXT88_RS20760	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BXT88_RS20805	COG2409	Drug exporters of the RND superfamily
BXT88_RS20810	COG1064	alcohol dehydrogenase
BXT88_RS20845	COG2268	Band 7 protein
BXT88_RS20865	COG0477	Major facilitator Superfamily
BXT88_RS20875	COG2030	dehydratase
BXT88_RS20905	COG3708	Transcriptional regulator
BXT88_RS20905	COG2207	Transcriptional regulator
BXT88_RS20940	COG2226	methyltransferase
BXT88_RS20975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BXT88_RS20980	COG1834	amidinotransferase
BXT88_RS20995	COG0477	Major facilitator Superfamily
BXT88_RS21000	COG0402	S-adenosylhomocysteine deaminase activity
BXT88_RS21020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXT88_RS21030	COG0477	Major facilitator Superfamily
BXT88_RS21035	COG1132	(ABC) transporter
BXT88_RS21055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BXT88_RS21060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BXT88_RS21110	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BXT88_RS21115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BXT88_RS21135	COG1595	DNA-templated transcription, initiation
BXT88_RS21180	COG1309	transcriptional regulator
BXT88_RS21210	COG4585	Histidine kinase
BXT88_RS21215	COG2197	response regulator
BXT88_RS21235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXT88_RS21240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXT88_RS21295	COG0463	Glycosyl transferase, family 2
BXT88_RS21335	COG4249	Peptidase C14 caspase catalytic subunit p20
BXT88_RS21335	COG2319	Wd-40 repeat
BXT88_RS21350	COG1408	metallophosphoesterase
BXT88_RS21360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXT88_RS21375	COG0003	Pfam Anion-transporting ATPase
BXT88_RS21400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXT88_RS21435	COG2267	carboxylic ester hydrolase activity
BXT88_RS21445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BXT88_RS21450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXT88_RS21510	COG1205	dead DEAH box helicase
BXT88_RS21510	COG1111	helicase
BXT88_RS21515	COG1366	Belongs to the anti-sigma-factor antagonist family
BXT88_RS21520	COG2172	sigma factor antagonist activity
BXT88_RS21525	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BXT88_RS21535	COG2890	protein-(glutamine-N5) methyltransferase activity
BXT88_RS21560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BXT88_RS21560	COG1754	DNA topoisomerase type I activity
BXT88_RS21565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BXT88_RS21570	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BXT88_RS21595	COG1175	transmembrane transport
BXT88_RS21605	COG0584	glycerophosphoryl diester phosphodiesterase
BXT88_RS21610	COG3594	Acyltransferase
BXT88_RS21615	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BXT88_RS21630	COG1309	transcriptional regulator
BXT88_RS21675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXT88_RS21675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BXT88_RS21690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BXT88_RS21695	COG0254	rRNA binding
BXT88_RS21720	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS21725	COG2318	DinB family
BXT88_RS21735	COG0076	glutamate decarboxylase activity
BXT88_RS21740	COG0655	NAD(P)H dehydrogenase (quinone) activity
BXT88_RS21750	COG0789	Transcriptional regulator
BXT88_RS21755	COG0393	Putative heavy-metal-binding
BXT88_RS21770	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BXT88_RS21775	COG2027	D-alanyl-D-alanine carboxypeptidase
BXT88_RS21785	COG0037	tRNA processing
BXT88_RS21800	COG0302	gtp cyclohydrolase
BXT88_RS21810	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BXT88_RS21810	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BXT88_RS21825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BXT88_RS21830	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BXT88_RS21840	COG0517	IMP dehydrogenase activity
BXT88_RS21840	COG1125	glycine betaine transport
BXT88_RS21845	COG1174	glycine betaine transport
BXT88_RS21850	COG1174	glycine betaine transport
BXT88_RS21865	COG0649	NAD binding
BXT88_RS21910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BXT88_RS21915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BXT88_RS21925	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BXT88_RS21945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BXT88_RS21975	COG0739	heme binding
BXT88_RS21990	COG2205	protein histidine kinase activity
BXT88_RS21995	COG0745	RESPONSE REGULATOR receiver
BXT88_RS22005	COG1595	DNA-templated transcription, initiation
BXT88_RS22010	COG1194	a g-specific adenine glycosylase
BXT88_RS22020	COG0671	phosphoesterase, PA-phosphatase related
BXT88_RS22035	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BXT88_RS22055	COG0248	Ppx GppA phosphatase
BXT88_RS22060	COG1082	Xylose isomerase domain protein TIM barrel
BXT88_RS22070	COG0129	dihydroxy-acid dehydratase activity
BXT88_RS22095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXT88_RS22095	COG0515	serine threonine protein kinase
BXT88_RS22140	COG0842	Transport permease protein
BXT88_RS22140	COG1129	ABC transporter
BXT88_RS22150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BXT88_RS22155	COG0180	Tryptophanyl-tRNA synthetase
BXT88_RS22205	COG0739	heme binding
BXT88_RS22205	COG0741	lytic transglycosylase activity
BXT88_RS22205	COG1196	nuclear chromosome segregation
BXT88_RS22210	COG0671	phosphoesterase, PA-phosphatase related
BXT88_RS22215	COG0277	FAD linked oxidase domain protein
BXT88_RS22230	COG1937	Protein conserved in bacteria
BXT88_RS22240	COG0306	phosphate transporter
BXT88_RS22245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BXT88_RS22250	COG0581	inorganic phosphate transmembrane transporter activity
BXT88_RS22300	COG1132	(ABC) transporter
BXT88_RS22305	COG2378	regulation of single-species biofilm formation
BXT88_RS22320	COG2890	protein-(glutamine-N5) methyltransferase activity
BXT88_RS22335	COG0667	Aldo Keto reductase
BXT88_RS22360	COG1733	regulation of RNA biosynthetic process
BXT88_RS22395	COG1490	D-aminoacyl-tRNA deacylase activity
BXT88_RS22405	COG0735	belongs to the Fur family
BXT88_RS22415	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BXT88_RS22420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXT88_RS22425	COG3485	protocatechuate 3,4-dioxygenase
BXT88_RS22445	COG2897	thiosulfate sulfurtransferase activity
BXT88_RS22490	COG0745	RESPONSE REGULATOR receiver
BXT88_RS22495	COG1609	Transcriptional regulator
BXT88_RS22500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXT88_RS22505	COG0745	RESPONSE REGULATOR receiver
BXT88_RS22520	COG0702	epimerase
BXT88_RS22530	COG0737	Belongs to the 5'-nucleotidase family
BXT88_RS22535	COG0456	acetyltransferase
BXT88_RS22545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXT88_RS22550	COG1131	(ABC) transporter
BXT88_RS22560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BXT88_RS22585	COG0667	Aldo Keto reductase
BXT88_RS22600	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS22615	COG4106	trans-aconitate 2-methyltransferase activity
BXT88_RS22645	COG0588	phosphoglycerate mutase activity
BXT88_RS22670	COG2226	methyltransferase
BXT88_RS22690	COG5002	protein histidine kinase activity
BXT88_RS22710	COG1329	Transcriptional regulator
BXT88_RS22715	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BXT88_RS22720	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BXT88_RS22725	COG3467	pyridoxamine 5'-phosphate
BXT88_RS22730	COG0215	cysteine-tRNA ligase activity
BXT88_RS22745	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BXT88_RS22755	COG3842	ATPase activity
BXT88_RS22795	COG2197	response regulator
BXT88_RS22825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BXT88_RS22855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BXT88_RS22885	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BXT88_RS22890	COG0463	Glycosyl transferase, family 2
BXT88_RS22905	COG1278	Cold shock
BXT88_RS22930	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BXT88_RS22935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BXT88_RS22970	COG2814	Major facilitator Superfamily
BXT88_RS22980	COG3973	AAA domain
BXT88_RS22995	COG1061	Type III restriction enzyme res subunit
BXT88_RS23010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BXT88_RS23015	COG1120	ATPase activity
BXT88_RS23020	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXT88_RS23025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXT88_RS23040	COG1278	Cold shock
BXT88_RS23045	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BXT88_RS23050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BXT88_RS23060	COG2814	Major facilitator Superfamily
BXT88_RS23100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BXT88_RS23110	COG2252	PERMEase
BXT88_RS23135	COG0667	Aldo Keto reductase
BXT88_RS23150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BXT88_RS23155	COG2378	regulation of single-species biofilm formation
BXT88_RS23165	COG0277	FAD linked oxidase domain protein
BXT88_RS23165	COG0247	lactate metabolic process
BXT88_RS23170	COG0583	DNA-binding transcription factor activity
BXT88_RS23175	COG5006	permease, DMT superfamily
BXT88_RS23185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BXT88_RS23200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXT88_RS23230	COG0259	pyridoxamine-phosphate oxidase activity
BXT88_RS23240	COG4821	SIS domain
BXT88_RS23250	COG0596	Alpha beta hydrolase
BXT88_RS23250	COG2945	thiolester hydrolase activity
BXT88_RS23275	COG1131	(ABC) transporter
BXT88_RS23330	COG4585	Histidine kinase
BXT88_RS23350	COG0515	serine threonine protein kinase
BXT88_RS23355	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS23375	COG0519	Catalyzes the synthesis of GMP from XMP
BXT88_RS23375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BXT88_RS23380	COG2084	Dehydrogenase
BXT88_RS23430	COG2815	serine threonine protein kinase
BXT88_RS23430	COG0515	serine threonine protein kinase
BXT88_RS23440	COG2197	response regulator
BXT88_RS23450	COG0791	NLP P60 protein
BXT88_RS23480	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BXT88_RS23495	COG0714	Associated with various cellular activities
BXT88_RS23500	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BXT88_RS23505	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BXT88_RS23520	COG0045	succinate-CoA ligase (ADP-forming) activity
BXT88_RS23555	COG0138	bifunctional purine biosynthesis protein purh
BXT88_RS23570	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BXT88_RS23600	COG0039	L-malate dehydrogenase activity
BXT88_RS23620	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS23630	COG0517	IMP dehydrogenase activity
BXT88_RS23630	COG4175	Glycine betaine
BXT88_RS23635	COG4176	ABC-type proline glycine betaine transport system permease component
BXT88_RS23665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXT88_RS23670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXT88_RS23675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXT88_RS23680	COG0456	acetyltransferase
BXT88_RS23750	COG0754	glutathionylspermidine amidase activity
BXT88_RS23760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BXT88_RS23765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BXT88_RS23770	COG0180	Tryptophanyl-tRNA synthetase
BXT88_RS23780	COG1295	ribonuclease BN
BXT88_RS23785	COG1686	Belongs to the peptidase S11 family
BXT88_RS23800	COG1408	metallophosphoesterase
BXT88_RS23850	COG0596	Alpha beta hydrolase
BXT88_RS23865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BXT88_RS23880	COG2009	succinate dehydrogenase
BXT88_RS23895	COG1595	DNA-templated transcription, initiation
BXT88_RS23910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BXT88_RS23910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BXT88_RS23925	COG2186	Transcriptional regulator
BXT88_RS23930	COG3265	gluconokinase activity
BXT88_RS23955	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BXT88_RS23965	COG1216	Glycosyl transferase, family 2
BXT88_RS23980	COG2089	acid synthase
BXT88_RS23990	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BXT88_RS23990	COG1473	amidohydrolase
BXT88_RS23995	COG1744	ABC transporter substrate-binding protein PnrA-like
BXT88_RS24000	COG3845	ABC transporter
BXT88_RS24005	COG4603	Belongs to the binding-protein-dependent transport system permease family
BXT88_RS24010	COG1079	Belongs to the binding-protein-dependent transport system permease family
BXT88_RS24025	COG2814	Major facilitator Superfamily
BXT88_RS24030	COG0583	DNA-binding transcription factor activity
BXT88_RS24055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BXT88_RS24080	COG2205	protein histidine kinase activity
BXT88_RS24085	COG0745	RESPONSE REGULATOR receiver
BXT88_RS24090	COG1595	DNA-templated transcription, initiation
BXT88_RS24110	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS24115	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS24120	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BXT88_RS24130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXT88_RS24165	COG4770	biotin carboxylase activity
BXT88_RS24185	COG0515	serine threonine protein kinase
BXT88_RS24185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXT88_RS24195	COG0693	protein deglycase activity
BXT88_RS24205	COG0424	maF-like protein
BXT88_RS24210	COG0768	penicillin binding
BXT88_RS24220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXT88_RS24230	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BXT88_RS24235	COG1024	Enoyl-CoA hydratase
BXT88_RS24245	COG2986	histidine ammonia-lyase
BXT88_RS24270	COG2197	response regulator
BXT88_RS24275	COG4585	Histidine kinase
BXT88_RS24290	COG1113	amino acid transport
BXT88_RS24310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXT88_RS24340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BXT88_RS24355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXT88_RS24365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BXT88_RS24380	COG1331	Highly conserved protein containing a thioredoxin domain
BXT88_RS24390	COG0154	amidase activity
BXT88_RS24405	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BXT88_RS24440	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BXT88_RS24455	COG1414	Transcriptional regulator
BXT88_RS24460	COG0251	oxidation-reduction process
BXT88_RS24465	COG2610	gluconate transmembrane transporter activity
BXT88_RS24510	COG2894	cell division
BXT88_RS24555	COG2885	chlorophyll binding
BXT88_RS24570	COG0640	Transcriptional regulator
BXT88_RS24585	COG0667	Aldo Keto reductase
BXT88_RS24590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BXT88_RS24595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BXT88_RS24610	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXT88_RS24615	COG0450	alkyl hydroperoxide reductase
BXT88_RS24635	COG1136	(ABC) transporter
BXT88_RS24650	COG1136	(ABC) transporter
BXT88_RS24690	COG0114	fumarate hydratase activity
BXT88_RS24710	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BXT88_RS24710	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BXT88_RS24735	COG0778	Nitroreductase
BXT88_RS24740	COG1722	exodeoxyribonuclease VII activity
BXT88_RS24745	COG1570	exodeoxyribonuclease VII activity
BXT88_RS24755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BXT88_RS24770	COG0012	GTP binding
BXT88_RS24775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BXT88_RS24780	COG0330	HflC and HflK could
BXT88_RS24820	COG0582	viral genome integration into host DNA
BXT88_RS24845	COG0531	amino acid
BXT88_RS24870	COG0402	S-adenosylhomocysteine deaminase activity
BXT88_RS24900	COG1217	gtp-binding protein TYPA
BXT88_RS24905	COG4166	transmembrane transport
BXT88_RS24910	COG0601	transmembrane transport
BXT88_RS24915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BXT88_RS24920	COG0444	Belongs to the ABC transporter superfamily
BXT88_RS24925	COG4608	Belongs to the ABC transporter superfamily
BXT88_RS24935	COG4608	Belongs to the ABC transporter superfamily
BXT88_RS24940	COG0444	Belongs to the ABC transporter superfamily
BXT88_RS24950	COG4166	transmembrane transport
BXT88_RS24955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BXT88_RS24975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BXT88_RS24990	COG1131	(ABC) transporter
BXT88_RS25000	COG4585	Histidine kinase
BXT88_RS25005	COG2197	response regulator
BXT88_RS25045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXT88_RS25050	COG1611	Belongs to the LOG family
BXT88_RS25055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BXT88_RS25065	COG0519	Catalyzes the synthesis of GMP from XMP
BXT88_RS25070	COG1024	Enoyl-CoA hydratase
BXT88_RS25085	COG1595	DNA-templated transcription, initiation
BXT88_RS25095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXT88_RS25100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXT88_RS25135	COG0598	Magnesium transport protein CorA
BXT88_RS25145	COG2814	Major facilitator Superfamily
BXT88_RS25155	COG0613	PHP domain protein
BXT88_RS25160	COG2095	MarC family integral membrane protein
BXT88_RS25165	COG1432	Conserved Protein
BXT88_RS25210	COG0596	Alpha beta hydrolase
BXT88_RS25210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXT88_RS25270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXT88_RS25310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXT88_RS25365	COG3480	Lon protease (S16) C-terminal proteolytic domain
BXT88_RS25375	COG1615	UPF0182 protein
BXT88_RS25415	COG0753	catalase activity
BXT88_RS25420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BXT88_RS25420	COG0517	IMP dehydrogenase activity
BXT88_RS25425	COG0483	inositol monophosphate 1-phosphatase activity
BXT88_RS25435	COG2076	Multidrug Resistance protein
BXT88_RS25440	COG1162	GTPase activity
BXT88_RS25445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BXT88_RS25455	COG2135	peptidase activity
BXT88_RS25465	COG3800	Transcriptional regulator
BXT88_RS25465	COG1396	sequence-specific DNA binding
BXT88_RS25470	COG1595	DNA-templated transcription, initiation
BXT88_RS25475	COG5662	AntiSigma factor
BXT88_RS25495	COG0242	peptide deformylase activity
BXT88_RS25500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXT88_RS25505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXT88_RS25530	COG2188	Transcriptional regulator
BXT88_RS25535	COG2182	Extracellular solute-binding protein
BXT88_RS25540	COG1175	transmembrane transport
BXT88_RS25545	COG0395	ABC-type sugar transport system, permease component
BXT88_RS25550	COG1472	Belongs to the glycosyl hydrolase 3 family
BXT88_RS25555	COG2364	Membrane
BXT88_RS25560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXT88_RS25565	COG0363	glucosamine-6-phosphate deaminase activity
BXT88_RS25570	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS25575	COG1309	transcriptional regulator
BXT88_RS25590	COG1597	lipid kinase activity
BXT88_RS25645	COG2066	Belongs to the glutaminase family
BXT88_RS25655	COG3415	Transposase
BXT88_RS25655	COG2801	Transposase and inactivated derivatives
BXT88_RS25665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXT88_RS25680	COG0477	Major facilitator Superfamily
BXT88_RS25685	COG0598	Magnesium transport protein CorA
BXT88_RS25690	COG2807	transmembrane transport
BXT88_RS25695	COG2186	Transcriptional regulator
BXT88_RS25700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BXT88_RS25705	COG1993	acr, cog1993
BXT88_RS25710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BXT88_RS25745	COG1278	Cold shock
BXT88_RS25750	COG0513	Belongs to the DEAD box helicase family
BXT88_RS25770	COG0681	Belongs to the peptidase S26 family
BXT88_RS25780	COG4106	trans-aconitate 2-methyltransferase activity
BXT88_RS25785	COG1126	abc transporter atp-binding protein
BXT88_RS25790	COG0765	amino acid transport
BXT88_RS25800	COG0281	malic enzyme
BXT88_RS25805	COG0604	alcohol dehydrogenase
BXT88_RS25865	COG2255	four-way junction helicase activity
BXT88_RS25890	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXT88_RS25890	COG0567	Dehydrogenase, E1 component
BXT88_RS25895	COG2205	protein histidine kinase activity
BXT88_RS25900	COG0745	RESPONSE REGULATOR receiver
BXT88_RS25920	COG1357	PFAM Pentapeptide repeats (8 copies)
BXT88_RS25925	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BXT88_RS26005	COG1119	ATPase activity
BXT88_RS26015	COG0768	penicillin binding
BXT88_RS26025	COG2124	cytochrome p450
BXT88_RS26035	COG0745	RESPONSE REGULATOR receiver
BXT88_RS26040	COG0018	arginyl-trna synthetase
BXT88_RS26045	COG0019	diaminopimelate decarboxylase activity
BXT88_RS26050	COG0460	homoserine dehydrogenase
BXT88_RS26055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BXT88_RS26060	COG0083	homoserine kinase activity
BXT88_RS26075	COG0254	rRNA binding
BXT88_RS26080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BXT88_RS26085	COG2890	protein-(glutamine-N5) methyltransferase activity
BXT88_RS26095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXT88_RS26100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BXT88_RS26120	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BXT88_RS26125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BXT88_RS26130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BXT88_RS26135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BXT88_RS26140	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BXT88_RS26145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BXT88_RS26150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BXT88_RS26160	COG2197	response regulator
BXT88_RS26165	COG3850	Histidine kinase
BXT88_RS26195	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXT88_RS26210	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BXT88_RS26270	COG0183	Belongs to the thiolase family
BXT88_RS26345	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BXT88_RS26345	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BXT88_RS26350	COG0642	Histidine kinase
BXT88_RS26350	COG3850	Histidine kinase
BXT88_RS26355	COG0745	RESPONSE REGULATOR receiver
BXT88_RS26360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BXT88_RS26365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXT88_RS26400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BXT88_RS26405	COG0857	belongs to the CobB CobQ family
BXT88_RS26405	COG0280	phosphate acetyltransferase
BXT88_RS26410	COG0205	6-phosphofructokinase activity
BXT88_RS26415	COG0577	efflux transmembrane transporter activity
BXT88_RS26420	COG0577	efflux transmembrane transporter activity
BXT88_RS26420	COG1136	(ABC) transporter
BXT88_RS26430	COG0395	ABC-type sugar transport system, permease component
BXT88_RS26445	COG4565	transcriptional regulatory protein
BXT88_RS26455	COG1301	dicarboxylic acid transport
BXT88_RS26465	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BXT88_RS26480	COG0366	Alpha amylase catalytic
BXT88_RS26485	COG4585	Histidine kinase
BXT88_RS26505	COG1132	(ABC) transporter
BXT88_RS26510	COG1132	(ABC) transporter
BXT88_RS26515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BXT88_RS26530	COG1132	(ABC) transporter
BXT88_RS26535	COG1132	(ABC) transporter
BXT88_RS26545	COG1376	ErfK ybiS ycfS ynhG family protein
BXT88_RS26550	COG1376	ErfK ybiS ycfS ynhG family protein
BXT88_RS26570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BXT88_RS26570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BXT88_RS26575	COG0785	Cytochrome C biogenesis protein
BXT88_RS26580	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BXT88_RS26590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BXT88_RS26600	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS26605	COG0745	RESPONSE REGULATOR receiver
BXT88_RS26630	COG0586	Pfam SNARE associated Golgi protein
BXT88_RS26650	COG1760	l-serine dehydratase
BXT88_RS26655	COG0531	amino acid
BXT88_RS26660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BXT88_RS26665	COG0509	glycine decarboxylation via glycine cleavage system
BXT88_RS26670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BXT88_RS26675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BXT88_RS26695	COG0747	negative chemotaxis
BXT88_RS26705	COG0444	Belongs to the ABC transporter superfamily
BXT88_RS26710	COG4608	Belongs to the ABC transporter superfamily
BXT88_RS26715	COG0308	aminopeptidase N
BXT88_RS26720	COG2860	membrane
BXT88_RS26745	COG0482	sulfurtransferase activity
BXT88_RS26755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BXT88_RS26765	COG4221	oxidoreductase activity
BXT88_RS26785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BXT88_RS26795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BXT88_RS26800	COG0154	amidase activity
BXT88_RS26810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BXT88_RS26835	COG2409	Drug exporters of the RND superfamily
BXT88_RS26855	COG1672	PFAM Archaeal ATPase
BXT88_RS26855	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BXT88_RS26860	COG2133	pyrroloquinoline quinone binding
BXT88_RS26865	COG0667	Aldo Keto reductase
BXT88_RS26875	COG3300	MHYT domain
BXT88_RS26875	COG5001	Diguanylate cyclase
BXT88_RS26885	COG0440	acetolactate synthase activity
BXT88_RS26890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BXT88_RS26895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXT88_RS26910	COG0583	DNA-binding transcription factor activity
BXT88_RS26925	COG0506	proline dehydrogenase activity
BXT88_RS26930	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS26940	COG0473	3-isopropylmalate dehydrogenase activity
BXT88_RS26945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BXT88_RS26955	COG0831	urea catabolic process
BXT88_RS26955	COG0832	Belongs to the urease beta subunit family
BXT88_RS26960	COG0804	urea catabolic process
BXT88_RS26965	COG2957	Belongs to the agmatine deiminase family
BXT88_RS26970	COG1309	transcriptional regulator
BXT88_RS26975	COG0477	Major facilitator Superfamily
BXT88_RS26985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXT88_RS26995	COG5492	domain, Protein
BXT88_RS27000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXT88_RS27025	COG2018	Roadblock/LC7 domain
BXT88_RS27045	COG2018	Roadblock/LC7 domain
BXT88_RS27060	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXT88_RS27065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXT88_RS27105	COG1414	Transcriptional regulator
BXT88_RS27110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BXT88_RS27115	COG0066	3-isopropylmalate dehydratase activity
BXT88_RS27125	COG0776	regulation of translation
BXT88_RS27135	COG1920	GTP binding
BXT88_RS27145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BXT88_RS27150	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXT88_RS27170	COG0351	phosphomethylpyrimidine kinase
BXT88_RS27175	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BXT88_RS27180	COG1461	Dihydroxyacetone kinase
BXT88_RS27190	COG0742	ribosomal rna small subunit methyltransferase
BXT88_RS27195	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BXT88_RS27210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BXT88_RS27215	COG0571	ribonuclease III activity
BXT88_RS27220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXT88_RS27225	COG1733	regulation of RNA biosynthetic process
BXT88_RS27235	COG2340	Cysteine-rich secretory protein family
BXT88_RS27240	COG1254	Belongs to the acylphosphatase family
BXT88_RS27250	COG1196	nuclear chromosome segregation
BXT88_RS27255	COG0477	Major facilitator Superfamily
BXT88_RS27270	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BXT88_RS27300	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BXT88_RS27320	COG0228	four-way junction DNA binding
BXT88_RS27325	COG1837	Belongs to the UPF0109 family
BXT88_RS27330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BXT88_RS27335	COG0336	Belongs to the RNA methyltransferase TrmD family
BXT88_RS27340	COG0335	large ribosomal subunit rRNA binding
BXT88_RS27345	COG0681	Belongs to the peptidase S26 family
BXT88_RS27355	COG0681	Belongs to the peptidase S26 family
BXT88_RS27360	COG0681	Belongs to the peptidase S26 family
BXT88_RS27375	COG0792	nuclease activity
BXT88_RS27390	COG1191	sigma factor activity
BXT88_RS27405	COG0052	Belongs to the universal ribosomal protein uS2 family
BXT88_RS27410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BXT88_RS27415	COG0528	UMP kinase activity
BXT88_RS27420	COG0233	cytoplasmic translational termination
BXT88_RS27425	COG0575	Belongs to the CDS family
BXT88_RS27430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BXT88_RS27440	COG4208	sulfate ABC transporter
BXT88_RS27445	COG3842	ATPase activity
BXT88_RS27480	COG4181	ATPase activity
BXT88_RS27485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BXT88_RS27495	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS27505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BXT88_RS27515	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS27525	COG3842	ATPase activity
BXT88_RS27530	COG1176	ABC-type spermidine putrescine transport system, permease component I
BXT88_RS27535	COG1177	transmembrane transport
BXT88_RS27540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXT88_RS27565	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS27575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BXT88_RS27580	COG0750	zinc metalloprotease
BXT88_RS27585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BXT88_RS27600	COG0442	prolyl-tRNA aminoacylation
BXT88_RS27605	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
BXT88_RS27620	COG0779	Required for maturation of 30S ribosomal subunits
BXT88_RS27635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BXT88_RS27645	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BXT88_RS27650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BXT88_RS27665	COG0455	bacterial-type flagellum organization
BXT88_RS27755	COG1674	ftsk spoiiie
BXT88_RS27765	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BXT88_RS27770	COG1185	polyribonucleotide nucleotidyltransferase activity
BXT88_RS27775	COG0612	Peptidase, M16
BXT88_RS27780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BXT88_RS27800	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BXT88_RS27805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXT88_RS27810	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BXT88_RS27840	COG2208	phosphoserine phosphatase activity
BXT88_RS27840	COG2770	Histidine kinase
BXT88_RS27845	COG4999	Histidine kinase
BXT88_RS27845	COG3850	Histidine kinase
BXT88_RS27845	COG3437	response regulator, receiver
BXT88_RS27845	COG2205	protein histidine kinase activity
BXT88_RS27855	COG1674	ftsk spoiiie
BXT88_RS27865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BXT88_RS27875	COG1058	Belongs to the CinA family
BXT88_RS27875	COG1546	Belongs to the CinA family
BXT88_RS27880	COG1396	sequence-specific DNA binding
BXT88_RS27885	COG0783	Belongs to the Dps family
BXT88_RS27895	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS27900	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXT88_RS27905	COG3415	Transposase
BXT88_RS27905	COG2801	Transposase and inactivated derivatives
BXT88_RS27910	COG1201	RNA secondary structure unwinding
BXT88_RS27940	COG0628	permease
BXT88_RS27965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXT88_RS27970	COG0765	amino acid transport
BXT88_RS27975	COG0765	amino acid transport
BXT88_RS27985	COG1126	abc transporter atp-binding protein
BXT88_RS27995	COG2205	protein histidine kinase activity
BXT88_RS28000	COG1278	Cold shock
BXT88_RS28015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BXT88_RS28030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXT88_RS28040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BXT88_RS28045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXT88_RS28055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BXT88_RS28090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BXT88_RS28095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BXT88_RS28100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXT88_RS28125	COG3226	Transcriptional regulator
BXT88_RS28130	COG0154	amidase activity
BXT88_RS28145	COG0488	(ABC) transporter
BXT88_RS28160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BXT88_RS28195	COG1802	Transcriptional regulator
BXT88_RS28200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXT88_RS28215	COG0187	DNA topoisomerase II activity
BXT88_RS28225	COG4585	Histidine kinase
BXT88_RS28230	COG2197	response regulator
BXT88_RS28240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXT88_RS28245	COG4565	transcriptional regulatory protein
BXT88_RS28250	COG3290	protein histidine kinase activity
BXT88_RS28265	COG0372	Belongs to the citrate synthase family
BXT88_RS28275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BXT88_RS28280	COG0612	Peptidase, M16
BXT88_RS28295	COG1802	Transcriptional regulator
BXT88_RS28300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXT88_RS28320	COG1435	thymidine kinase activity
BXT88_RS28355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BXT88_RS28360	COG0483	inositol monophosphate 1-phosphatase activity
BXT88_RS28365	COG0745	RESPONSE REGULATOR receiver
BXT88_RS28370	COG2205	protein histidine kinase activity
BXT88_RS28395	COG0756	dUTP diphosphatase activity
BXT88_RS28410	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BXT88_RS28415	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BXT88_RS28420	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BXT88_RS28430	COG1136	(ABC) transporter
BXT88_RS28430	COG4591	ABC-type transport system involved in lipoprotein release permease component
BXT88_RS28435	COG0667	Aldo Keto reductase
BXT88_RS28470	COG0569	domain protein
BXT88_RS28480	COG0531	amino acid
BXT88_RS28485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXT88_RS28495	COG2801	Transposase and inactivated derivatives
BXT88_RS28495	COG3415	Transposase
BXT88_RS28515	COG1201	RNA secondary structure unwinding
BXT88_RS28560	COG2197	response regulator
BXT88_RS28565	COG1674	ftsk spoiiie
BXT88_RS28585	COG0464	growth
BXT88_RS28630	COG3629	intracellular signal transduction
BXT88_RS28630	COG3903	Transcriptional regulator
BXT88_RS28640	COG2197	response regulator
BXT88_RS28640	COG3903	Transcriptional regulator
BXT88_RS28650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXT88_RS28655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXT88_RS28705	COG0154	amidase activity
BXT88_RS28720	COG0789	Transcriptional regulator
BXT88_RS28735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BXT88_RS28745	COG4044	May play a role in the intracellular transport of hydrophobic ligands
BXT88_RS28765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BXT88_RS28770	COG0443	Heat shock 70 kDa protein
BXT88_RS28775	COG3424	synthase
BXT88_RS28780	COG2124	cytochrome p450
BXT88_RS28795	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BXT88_RS28800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS28805	COG2175	clavaminate synthase activity
BXT88_RS28840	COG3251	PFAM MbtH domain protein
BXT88_RS28845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS28850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS28855	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BXT88_RS28855	COG0235	Class ii aldolase
BXT88_RS28860	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BXT88_RS28865	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BXT88_RS28870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BXT88_RS28890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXT88_RS28910	COG0842	Transport permease protein
BXT88_RS28920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXT88_RS28930	COG0598	Magnesium transport protein CorA
BXT88_RS28935	COG1799	cell septum assembly
BXT88_RS28965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BXT88_RS28975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BXT88_RS28985	COG1024	Enoyl-CoA hydratase
BXT88_RS29015	COG0546	phosphoglycolate phosphatase activity
BXT88_RS29050	COG0484	heat shock protein binding
BXT88_RS29075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BXT88_RS29095	COG3480	Lon protease (S16) C-terminal proteolytic domain
BXT88_RS29100	COG1595	DNA-templated transcription, initiation
BXT88_RS29105	COG1902	pentaerythritol trinitrate reductase activity
BXT88_RS29110	COG1595	DNA-templated transcription, initiation
BXT88_RS29120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BXT88_RS29135	COG1653	transport
BXT88_RS29140	COG1175	transmembrane transport
BXT88_RS29145	COG0395	ABC-type sugar transport system, permease component
BXT88_RS29155	COG4213	ABC transporter substrate-binding protein
BXT88_RS29165	COG4214	carbohydrate transport
BXT88_RS29170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BXT88_RS29175	COG0531	amino acid
BXT88_RS29185	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXT88_RS29185	COG1024	Enoyl-CoA hydratase
BXT88_RS29190	COG0183	Belongs to the thiolase family
BXT88_RS29200	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BXT88_RS29215	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BXT88_RS29225	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXT88_RS29235	COG0183	Belongs to the thiolase family
BXT88_RS29240	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BXT88_RS29245	COG3253	May function as heme-dependent peroxidase
BXT88_RS29270	COG1280	lysine exporter protein (LysE YggA)
BXT88_RS29280	COG1136	(ABC) transporter
BXT88_RS29335	COG4585	Histidine kinase
BXT88_RS29340	COG2197	response regulator
BXT88_RS29345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXT88_RS29350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXT88_RS29360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BXT88_RS29385	COG1295	ribonuclease BN
BXT88_RS29410	COG0693	protein deglycase activity
BXT88_RS29430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXT88_RS29435	COG0583	DNA-binding transcription factor activity
BXT88_RS29470	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS29510	COG0477	Major facilitator Superfamily
BXT88_RS29535	COG1609	Transcriptional regulator
BXT88_RS29540	COG0366	Alpha amylase catalytic
BXT88_RS29550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXT88_RS29555	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BXT88_RS29575	COG0529	Catalyzes the synthesis of activated sulfate
BXT88_RS29580	COG0175	sulfate reduction
BXT88_RS29605	COG0596	Alpha beta hydrolase
BXT88_RS29610	COG2770	Histidine kinase
BXT88_RS29610	COG2208	phosphoserine phosphatase activity
BXT88_RS29635	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS29645	COG2814	Major facilitator Superfamily
BXT88_RS29650	COG1414	Transcriptional regulator
BXT88_RS29655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BXT88_RS29660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BXT88_RS29670	COG3485	protocatechuate 3,4-dioxygenase
BXT88_RS29675	COG3485	protocatechuate 3,4-dioxygenase
BXT88_RS29685	COG0596	Alpha beta hydrolase
BXT88_RS29740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BXT88_RS29760	COG2080	2 iron, 2 sulfur cluster binding
BXT88_RS29765	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BXT88_RS29770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BXT88_RS29780	COG3511	phospholipase C
BXT88_RS29785	COG0667	Aldo Keto reductase
BXT88_RS29800	COG1376	ErfK ybiS ycfS ynhG family protein
BXT88_RS29825	COG0842	Transport permease protein
BXT88_RS29825	COG1716	ATPase activity
BXT88_RS29825	COG1131	(ABC) transporter
BXT88_RS29880	COG5001	Diguanylate cyclase
BXT88_RS29895	COG3290	protein histidine kinase activity
BXT88_RS29905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BXT88_RS29925	COG3321	synthase
BXT88_RS29925	COG0604	alcohol dehydrogenase
BXT88_RS29925	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS29930	COG1162	GTPase activity
BXT88_RS29950	COG0028	Belongs to the TPP enzyme family
BXT88_RS29975	COG1802	Transcriptional regulator
BXT88_RS30005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BXT88_RS30010	COG2252	PERMEase
BXT88_RS30025	COG0583	DNA-binding transcription factor activity
BXT88_RS30035	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS30085	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS30095	COG2315	Protein conserved in bacteria
BXT88_RS30130	COG0753	catalase activity
BXT88_RS30135	COG0028	Belongs to the TPP enzyme family
BXT88_RS30140	COG2084	Dehydrogenase
BXT88_RS30145	COG3622	Belongs to the hyi family
BXT88_RS30165	COG2351	hydroxyisourate hydrolase activity
BXT88_RS30175	COG2233	PERMEase
BXT88_RS30185	COG2233	PERMEase
BXT88_RS30205	COG1288	antiporter activity
BXT88_RS30210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BXT88_RS30235	COG1414	Transcriptional regulator
BXT88_RS30245	COG1953	Uracil, thiamine, allantoin
BXT88_RS30250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BXT88_RS30255	COG4266	Belongs to the allantoicase family
BXT88_RS30295	COG0800	Aldolase
BXT88_RS30305	COG2249	NAD(P)H dehydrogenase (quinone) activity
BXT88_RS30315	COG2188	Transcriptional regulator
BXT88_RS30330	COG1172	Belongs to the binding-protein-dependent transport system permease family
BXT88_RS30340	COG1940	carbohydrate kinase activity
BXT88_RS30350	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BXT88_RS30355	COG2197	response regulator
BXT88_RS30375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXT88_RS30380	COG2124	cytochrome p450
BXT88_RS30385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BXT88_RS30480	COG3391	amine dehydrogenase activity
BXT88_RS30550	COG0542	response to heat
BXT88_RS30565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BXT88_RS30570	COG0443	Heat shock 70 kDa protein
BXT88_RS30580	COG3835	regulator
BXT88_RS30590	COG1289	transmembrane transporter activity
BXT88_RS30615	COG1309	transcriptional regulator
BXT88_RS30625	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS30645	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS30660	COG0667	Aldo Keto reductase
BXT88_RS30705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXT88_RS30730	COG1126	abc transporter atp-binding protein
BXT88_RS30735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXT88_RS30740	COG0765	amino acid transport
BXT88_RS30745	COG0765	amino acid transport
BXT88_RS30765	COG2226	methyltransferase
BXT88_RS30770	COG2267	carboxylic ester hydrolase activity
BXT88_RS30775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXT88_RS30785	COG0435	Glutathione S-transferase
BXT88_RS30795	COG2409	Drug exporters of the RND superfamily
BXT88_RS30810	COG0387	Pfam Sodium calcium exchanger
BXT88_RS30825	COG1335	isochorismatase
BXT88_RS30830	COG0477	Major facilitator Superfamily
BXT88_RS30845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BXT88_RS30855	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BXT88_RS30860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS30865	COG1953	Uracil, thiamine, allantoin
BXT88_RS30870	COG0095	Lipoate-protein ligase
BXT88_RS30875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BXT88_RS30885	COG0483	inositol monophosphate 1-phosphatase activity
BXT88_RS30900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXT88_RS30905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BXT88_RS30910	COG1937	Protein conserved in bacteria
BXT88_RS30915	COG0730	response to heat
BXT88_RS30920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BXT88_RS30935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BXT88_RS30960	COG1929	Belongs to the glycerate kinase type-1 family
BXT88_RS30970	COG0688	phosphatidylethanolamine metabolic process
BXT88_RS30975	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS30985	COG2301	Belongs to the HpcH HpaI aldolase family
BXT88_RS30990	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BXT88_RS30990	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BXT88_RS31005	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXT88_RS31015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BXT88_RS31025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXT88_RS31030	COG0456	acetyltransferase
BXT88_RS31080	COG2362	D-Aminopeptidase
BXT88_RS31085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXT88_RS31095	COG1619	proteins homologs of microcin C7 resistance protein MccF
BXT88_RS31110	COG2124	cytochrome p450
BXT88_RS31125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BXT88_RS31135	COG0010	Belongs to the arginase family
BXT88_RS31145	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS31170	COG2226	methyltransferase
BXT88_RS31175	COG1597	lipid kinase activity
BXT88_RS31200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BXT88_RS31210	COG0531	amino acid
BXT88_RS31235	COG2154	pterin-4-alpha-carbinolamine dehydratase
BXT88_RS31240	COG1295	ribonuclease BN
BXT88_RS31265	COG0656	L-ascorbic acid biosynthetic process
BXT88_RS31275	COG0583	DNA-binding transcription factor activity
BXT88_RS31290	COG3321	synthase
BXT88_RS31290	COG0604	alcohol dehydrogenase
BXT88_RS31290	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS31300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BXT88_RS31305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXT88_RS31310	COG1605	Chorismate mutase
BXT88_RS31310	COG0287	Prephenate dehydrogenase
BXT88_RS31315	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS31330	COG0531	amino acid
BXT88_RS31335	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS31350	COG1136	(ABC) transporter
BXT88_RS31385	COG0583	DNA-binding transcription factor activity
BXT88_RS31425	COG2205	protein histidine kinase activity
BXT88_RS31430	COG0745	RESPONSE REGULATOR receiver
BXT88_RS31455	COG3226	Transcriptional regulator
BXT88_RS31470	COG1846	Transcriptional regulator
BXT88_RS31485	COG1309	transcriptional regulator
BXT88_RS31495	COG1349	DNA-binding transcription factor activity
BXT88_RS31505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXT88_RS31510	COG2814	Major facilitator Superfamily
BXT88_RS31525	COG1515	deoxyribonuclease V activity
BXT88_RS31530	COG3268	Saccharopine dehydrogenase
BXT88_RS31540	COG1285	pathogenesis
BXT88_RS31545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BXT88_RS31550	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS31555	COG0183	Belongs to the thiolase family
BXT88_RS31560	COG1024	Enoyl-CoA hydratase
BXT88_RS31560	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXT88_RS31565	COG0789	Transcriptional regulator
BXT88_RS31570	COG1113	amino acid transport
BXT88_RS31575	COG3568	Endonuclease Exonuclease Phosphatase
BXT88_RS31590	COG2936	dipeptidyl-peptidase activity
BXT88_RS31600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BXT88_RS31640	COG2183	response to ionizing radiation
BXT88_RS31650	COG4977	sequence-specific DNA binding
BXT88_RS31680	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BXT88_RS31715	COG1134	teichoic acid transport
BXT88_RS31720	COG1562	ergosterol biosynthetic process
BXT88_RS31730	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BXT88_RS31740	COG1657	PFAM Prenyltransferase squalene oxidase
BXT88_RS31755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BXT88_RS31765	COG2365	Tyrosine phosphatase family
BXT88_RS31770	COG2755	lipolytic protein G-D-S-L family
BXT88_RS31795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXT88_RS31825	COG2018	Roadblock/LC7 domain
BXT88_RS31850	COG1228	amidohydrolase
BXT88_RS31855	COG2267	carboxylic ester hydrolase activity
BXT88_RS31860	COG3958	Transketolase
BXT88_RS31865	COG3959	Transketolase, thiamine diphosphate binding domain
BXT88_RS31895	COG2124	cytochrome p450
BXT88_RS31900	COG1686	Belongs to the peptidase S11 family
BXT88_RS31905	COG3655	Transcriptional regulator
BXT88_RS31935	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXT88_RS31940	COG3246	L-lysine catabolic process to acetate
BXT88_RS31955	COG0174	glutamine synthetase
BXT88_RS31985	COG1940	carbohydrate kinase activity
BXT88_RS31990	COG0747	negative chemotaxis
BXT88_RS32000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BXT88_RS32035	COG1024	Enoyl-CoA hydratase
BXT88_RS32040	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS32050	COG1113	amino acid transport
BXT88_RS32055	COG2706	6-phosphogluconolactonase activity
BXT88_RS32070	COG2133	pyrroloquinoline quinone binding
BXT88_RS32070	COG5183	chlorophyll binding
BXT88_RS32085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BXT88_RS32145	COG3537	Alpha-1,2-mannosidase
BXT88_RS32160	COG0531	amino acid
BXT88_RS32165	COG3360	Dodecin
BXT88_RS32185	COG2226	methyltransferase
BXT88_RS32215	COG0823	Involved in the tonB-independent uptake of proteins
BXT88_RS32220	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BXT88_RS32230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXT88_RS32235	COG3572	ergothioneine biosynthetic process
BXT88_RS32265	COG1388	LysM domain
BXT88_RS32265	COG3858	chitin binding
BXT88_RS32280	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS32285	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS32315	COG0583	DNA-binding transcription factor activity
BXT88_RS32325	COG1024	Enoyl-CoA hydratase
BXT88_RS32335	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXT88_RS32340	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS32345	COG1349	DNA-binding transcription factor activity
BXT88_RS32350	COG2814	Major facilitator Superfamily
BXT88_RS32355	COG1070	Carbohydrate kinase
BXT88_RS32360	COG1070	Carbohydrate kinase
BXT88_RS32365	COG0588	phosphoglycerate mutase activity
BXT88_RS32370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXT88_RS32420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BXT88_RS32420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BXT88_RS32440	COG3023	N-Acetylmuramoyl-L-alanine amidase
BXT88_RS32445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXT88_RS32445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXT88_RS32450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXT88_RS32460	COG1070	Carbohydrate kinase
BXT88_RS32465	COG2115	Belongs to the xylose isomerase family
BXT88_RS32470	COG3458	cephalosporin-C deacetylase activity
BXT88_RS32490	COG0765	amino acid transport
BXT88_RS32495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXT88_RS32500	COG2040	homocysteine
BXT88_RS32510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXT88_RS32520	COG0431	NADPH-dependent FMN reductase
BXT88_RS32545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BXT88_RS32585	COG2018	Roadblock/LC7 domain
BXT88_RS32595	COG1946	Acyl-CoA thioesterase
BXT88_RS32610	COG1132	(ABC) transporter
BXT88_RS32615	COG1132	(ABC) transporter
BXT88_RS32645	COG1132	(ABC) transporter
BXT88_RS32665	COG0494	nUDIX hydrolase
BXT88_RS32680	COG1556	Lactate utilization protein
BXT88_RS32685	COG1139	Iron-sulfur cluster binding protein
BXT88_RS32690	COG0247	lactate metabolic process
BXT88_RS32695	COG0477	Major facilitator Superfamily
BXT88_RS32700	COG0492	ferredoxin-NADP+ reductase activity
BXT88_RS32715	COG1116	anion transmembrane transporter activity
BXT88_RS32720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXT88_RS32725	COG0432	Pfam Uncharacterised protein family UPF0047
BXT88_RS32765	COG3170	Tfp pilus assembly protein FimV
BXT88_RS32780	COG3291	Pkd domain containing protein
BXT88_RS32840	COG2267	carboxylic ester hydrolase activity
BXT88_RS32855	COG0583	DNA-binding transcription factor activity
BXT88_RS32860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BXT88_RS32870	COG0405	Gamma-glutamyltransferase
BXT88_RS32975	COG0183	Belongs to the thiolase family
BXT88_RS32980	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS32985	COG1268	BioY protein
BXT88_RS32990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BXT88_RS32995	COG1122	ATPase activity
BXT88_RS33010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BXT88_RS33015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BXT88_RS33020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BXT88_RS33030	COG0156	8-amino-7-oxononanoate synthase activity
BXT88_RS33040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXT88_RS33055	COG4221	oxidoreductase activity
BXT88_RS33065	COG2080	2 iron, 2 sulfur cluster binding
BXT88_RS33070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BXT88_RS33075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BXT88_RS33105	COG2197	response regulator
BXT88_RS33155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BXT88_RS33170	COG4213	ABC transporter substrate-binding protein
BXT88_RS33175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BXT88_RS33220	COG2706	6-phosphogluconolactonase activity
BXT88_RS33245	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BXT88_RS33255	COG1902	pentaerythritol trinitrate reductase activity
BXT88_RS33300	COG0142	geranyltranstransferase activity
BXT88_RS33325	COG3629	intracellular signal transduction
BXT88_RS33325	COG3903	Transcriptional regulator
BXT88_RS33335	COG1302	Protein conserved in bacteria
BXT88_RS33345	COG1252	NADH dehydrogenase
BXT88_RS33355	COG0437	4 iron, 4 sulfur cluster binding
BXT88_RS33360	COG0243	molybdopterin cofactor binding
BXT88_RS33360	COG3383	formate dehydrogenase (NAD+) activity
BXT88_RS33370	COG1335	isochorismatase
BXT88_RS33390	COG0477	Major facilitator Superfamily
BXT88_RS33395	COG1957	nucleoside hydrolase
BXT88_RS33400	COG1609	Transcriptional regulator
BXT88_RS33430	COG3961	Belongs to the TPP enzyme family
BXT88_RS33435	COG1231	oxidoreductase activity
BXT88_RS33445	COG1733	regulation of RNA biosynthetic process
BXT88_RS33460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BXT88_RS33470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BXT88_RS33475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BXT88_RS33485	COG2135	peptidase activity
BXT88_RS33495	COG0662	Cupin 2, conserved barrel domain protein
BXT88_RS33510	COG1191	sigma factor activity
BXT88_RS33570	COG2304	oxidoreductase activity
BXT88_RS33580	COG2318	DinB family
BXT88_RS33610	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BXT88_RS33615	COG3251	PFAM MbtH domain protein
BXT88_RS33620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS33625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS33630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS33635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BXT88_RS33640	COG3629	intracellular signal transduction
BXT88_RS33640	COG3903	Transcriptional regulator
BXT88_RS33670	COG1335	isochorismatase
BXT88_RS33710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BXT88_RS33715	COG3958	Transketolase
BXT88_RS33720	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BXT88_RS33725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXT88_RS33730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BXT88_RS33745	COG0189	ligase activity
BXT88_RS33755	COG3903	Transcriptional regulator
BXT88_RS33755	COG3629	intracellular signal transduction
BXT88_RS33760	COG0513	Belongs to the DEAD box helicase family
BXT88_RS33785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXT88_RS33805	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BXT88_RS33820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BXT88_RS33835	COG1012	belongs to the aldehyde dehydrogenase family
BXT88_RS33855	COG1309	transcriptional regulator
BXT88_RS33865	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS33890	COG1228	amidohydrolase
BXT88_RS33900	COG1216	Glycosyl transferase, family 2
BXT88_RS33915	COG2270	Major facilitator Superfamily
BXT88_RS33925	COG2364	Membrane
BXT88_RS33945	COG3012	SEC-C Motif Domain Protein
BXT88_RS33955	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BXT88_RS33960	COG1793	dna ligase
BXT88_RS33960	COG3285	dna ligase
BXT88_RS33975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXT88_RS33980	COG2814	Major facilitator Superfamily
BXT88_RS33985	COG2356	endonuclease I
BXT88_RS33990	COG1686	Belongs to the peptidase S11 family
BXT88_RS33995	COG1278	Cold shock
BXT88_RS34035	COG0395	ABC-type sugar transport system, permease component
BXT88_RS34040	COG1175	transmembrane transport
BXT88_RS34045	COG1653	transport
BXT88_RS34050	COG1609	Transcriptional regulator
BXT88_RS34055	COG0702	epimerase
BXT88_RS34060	COG1132	(ABC) transporter
BXT88_RS34070	COG0739	heme binding
BXT88_RS34110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXT88_RS34120	COG1846	Transcriptional regulator
BXT88_RS34125	COG1764	response to oxidative stress
BXT88_RS34130	COG2723	6-phospho-beta-galactosidase activity
BXT88_RS34135	COG0395	ABC-type sugar transport system, permease component
BXT88_RS34140	COG1175	transmembrane transport
BXT88_RS34150	COG1940	carbohydrate kinase activity
BXT88_RS34180	COG2770	Histidine kinase
BXT88_RS34180	COG2208	phosphoserine phosphatase activity
BXT88_RS34205	COG1968	undecaprenyl-diphosphatase activity
BXT88_RS34215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BXT88_RS34295	COG1832	CoA-binding protein
BXT88_RS34305	COG1739	Uncharacterized protein family UPF0029
BXT88_RS34310	COG0531	amino acid
BXT88_RS34320	COG0477	Major facilitator Superfamily
BXT88_RS34380	COG1136	(ABC) transporter
BXT88_RS34390	COG0420	3'-5' exonuclease activity
BXT88_RS34395	COG0419	ATPase involved in DNA repair
BXT88_RS34400	COG1522	sequence-specific DNA binding
BXT88_RS34410	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS34440	COG1595	DNA-templated transcription, initiation
BXT88_RS34445	COG2188	Transcriptional regulator
BXT88_RS34450	COG1940	carbohydrate kinase activity
BXT88_RS34455	COG2197	response regulator
BXT88_RS34460	COG4585	Histidine kinase
BXT88_RS34480	COG3511	phospholipase C
BXT88_RS34490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BXT88_RS34535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BXT88_RS34540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BXT88_RS34545	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BXT88_RS34550	COG0156	8-amino-7-oxononanoate synthase activity
BXT88_RS34565	COG0741	lytic transglycosylase activity
BXT88_RS34565	COG0791	NLP P60 protein
BXT88_RS34575	COG0740	serine-type endopeptidase activity
BXT88_RS34590	COG0831	urea catabolic process
BXT88_RS34595	COG0832	Belongs to the urease beta subunit family
BXT88_RS34600	COG0804	urea catabolic process
BXT88_RS34610	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BXT88_RS34615	COG0829	nickel cation binding
BXT88_RS34675	COG3336	cytochrome c oxidase
BXT88_RS34680	COG0205	6-phosphofructokinase activity
BXT88_RS34685	COG3442	glutamine amidotransferase
BXT88_RS34695	COG0242	peptide deformylase activity
BXT88_RS34705	COG1960	acyl-CoA dehydrogenase activity
BXT88_RS34740	COG3960	tartronate-semialdehyde synthase activity
BXT88_RS34745	COG3622	Belongs to the hyi family
BXT88_RS34750	COG2084	Dehydrogenase
BXT88_RS34760	COG2124	cytochrome p450
BXT88_RS34785	COG1028	Short-chain dehydrogenase reductase Sdr
BXT88_RS34820	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BXT88_RS34850	COG0375	protein maturation
BXT88_RS34860	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BXT88_RS34865	COG0298	carbon dioxide binding
BXT88_RS34875	COG0309	Hydrogenase expression formation protein (HypE)
BXT88_RS34880	COG2837	iron assimilation
BXT88_RS34900	COG0640	Transcriptional regulator
BXT88_RS34905	COG0531	amino acid
BXT88_RS34920	COG1793	dna ligase
BXT88_RS34940	COG0318	PFAM AMP-dependent synthetase and ligase
BXT88_RS34960	COG3290	protein histidine kinase activity
BXT88_RS34970	COG1349	DNA-binding transcription factor activity
BXT88_RS34975	COG3395	kinase activity
BXT88_RS34980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BXT88_RS34990	COG2226	methyltransferase
BXT88_RS35025	COG2124	cytochrome p450
BXT88_RS35055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BXT88_RS35070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BXT88_RS35080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXT88_RS35095	COG2188	Transcriptional regulator
BXT88_RS35125	COG0583	DNA-binding transcription factor activity
BXT88_RS35145	COG1652	LysM domain
BXT88_RS35165	COG4221	oxidoreductase activity
BXT88_RS35225	COG2226	methyltransferase
BXT88_RS35230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BXT88_RS35235	COG2318	DinB family
BXT88_RS35265	COG0328	RNA-DNA hybrid ribonuclease activity
BXT88_RS35310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXT88_RS35315	COG2267	carboxylic ester hydrolase activity
BXT88_RS35320	COG0583	DNA-binding transcription factor activity
BXT88_RS35335	COG2340	Cysteine-rich secretory protein family
BXT88_RS35340	COG0583	DNA-binding transcription factor activity
BXT88_RS35375	COG0395	ABC-type sugar transport system, permease component
BXT88_RS35380	COG1175	transmembrane transport
BXT88_RS35385	COG1653	transport
BXT88_RS35390	COG0366	Alpha amylase catalytic
BXT88_RS35395	COG1653	transport
BXT88_RS35405	COG1136	(ABC) transporter
BXT88_RS35405	COG0577	efflux transmembrane transporter activity
BXT88_RS35425	COG2205	protein histidine kinase activity
BXT88_RS35460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXT88_RS35465	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
BXT88_RS35470	COG2223	nitrite transmembrane transporter activity
BXT88_RS35475	COG2207	Transcriptional regulator
BXT88_RS35500	COG0277	FAD linked oxidase domain protein
BXT88_RS35505	COG0494	nUDIX hydrolase
BXT88_RS35525	COG4221	oxidoreductase activity
BXT88_RS35530	COG0431	NADPH-dependent FMN reductase
BXT88_RS35535	COG2423	ornithine cyclodeaminase activity
BXT88_RS35555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXT88_RS35580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXT88_RS35610	COG1660	Displays ATPase and GTPase activities
BXT88_RS35705	COG0297	glycogen (starch) synthase activity
BXT88_RS35710	COG0438	transferase activity, transferring glycosyl groups
BXT88_RS35715	COG0110	maltose O-acetyltransferase activity
BXT88_RS35720	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BXT88_RS35725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXT88_RS35730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BXT88_RS35755	COG1191	sigma factor activity
BXT88_RS35765	COG3387	PFAM Glycoside hydrolase 15-related
BXT88_RS35800	COG0142	geranyltranstransferase activity
BXT88_RS35810	COG2208	phosphoserine phosphatase activity
BXT88_RS35810	COG2770	Histidine kinase
BXT88_RS35845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXT88_RS35850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXT88_RS35850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXT88_RS35855	COG3226	Transcriptional regulator
BXT88_RS35860	COG0596	Alpha beta hydrolase
BXT88_RS35890	COG0531	amino acid
BXT88_RS35910	COG1215	transferase activity, transferring glycosyl groups
BXT88_RS35915	COG1316	TRANSCRIPTIONal
BXT88_RS35920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BXT88_RS36010	COG3973	AAA domain
BXT88_RS36040	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BXT88_RS36050	COG0583	DNA-binding transcription factor activity
BXT88_RS36075	COG0753	catalase activity
BXT88_RS36090	COG1595	DNA-templated transcription, initiation
BXT88_RS36115	COG0488	(ABC) transporter
BXT88_RS36140	COG0596	Alpha beta hydrolase
BXT88_RS36160	COG0583	DNA-binding transcription factor activity
BXT88_RS36195	COG0366	Alpha amylase catalytic
BXT88_RS36210	COG1653	transport
BXT88_RS36215	COG3842	ATPase activity
BXT88_RS36220	COG1609	Transcriptional regulator
BXT88_RS36225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BXT88_RS36230	COG0789	Transcriptional regulator
BXT88_RS36265	COG1511	domain protein
BXT88_RS36270	COG3842	ATPase activity
BXT88_RS36275	COG1595	DNA-templated transcription, initiation
BXT88_RS36280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXT88_RS36305	COG0436	Aminotransferase
BXT88_RS36315	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXT88_RS36320	COG1595	DNA-templated transcription, initiation
BXT88_RS36335	COG1476	TRANSCRIPTIONal
BXT88_RS36355	COG0477	Major facilitator Superfamily
BXT88_RS36360	COG4941	Belongs to the sigma-70 factor family
BXT88_RS36365	COG3795	YCII-related domain
BXT88_RS36405	COG1522	sequence-specific DNA binding
BXT88_RS36435	COG1733	regulation of RNA biosynthetic process
BXT88_RS36440	COG0702	epimerase
BXT88_RS36475	COG1309	transcriptional regulator